WO2008092435A3 - Biologisch abbaubare gefässstütze - Google Patents

Biologisch abbaubare gefässstütze Download PDF

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Publication number
WO2008092435A3
WO2008092435A3 PCT/DE2008/000160 DE2008000160W WO2008092435A3 WO 2008092435 A3 WO2008092435 A3 WO 2008092435A3 DE 2008000160 W DE2008000160 W DE 2008000160W WO 2008092435 A3 WO2008092435 A3 WO 2008092435A3
Authority
WO
WIPO (PCT)
Prior art keywords
biodegradable
vascular support
biodegradable vascular
athrombogenic
migrative
Prior art date
Application number
PCT/DE2008/000160
Other languages
English (en)
French (fr)
Other versions
WO2008092435A9 (de
WO2008092435A2 (de
Inventor
Erika Hoffmann
Michael Hoffmann
Roland Horres
Original Assignee
Hemoteq Ag
Erika Hoffmann
Michael Hoffmann
Roland Horres
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE200710034350 external-priority patent/DE102007034350A1/de
Priority to JP2009547528A priority Critical patent/JP5391082B2/ja
Priority to US12/520,976 priority patent/US20100076544A1/en
Priority to EP08706826.8A priority patent/EP2114481B1/de
Priority to CN200880003444.3A priority patent/CN101636187B/zh
Priority to AU2008210149A priority patent/AU2008210149B2/en
Priority to BRPI0807830A priority patent/BRPI0807830B8/pt
Priority to ES08706826.8T priority patent/ES2557170T3/es
Application filed by Hemoteq Ag, Erika Hoffmann, Michael Hoffmann, Roland Horres filed Critical Hemoteq Ag
Priority to MX2009008064A priority patent/MX2009008064A/es
Priority to CA2673914A priority patent/CA2673914C/en
Priority to PL08706826T priority patent/PL2114481T3/pl
Publication of WO2008092435A2 publication Critical patent/WO2008092435A2/de
Priority to IL199569A priority patent/IL199569A/en
Publication of WO2008092435A3 publication Critical patent/WO2008092435A3/de
Publication of WO2008092435A9 publication Critical patent/WO2008092435A9/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02—Inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/02—Inorganic materials
    • A61L31/022—Metals or alloys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/148—Materials at least partially resorbable by the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
    • A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/42—Anti-thrombotic agents, anticoagulants, anti-platelet agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Surgery (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Cardiology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Materials For Medical Uses (AREA)

Abstract

Die vorliegende Erfindung betrifft biologisch abbaubare Gefässstützen, welche aus einem inneren biodegradierbaren metallischen Gerüst und einer äusseren polymeren Beschichtung bestehen. Die bioabbaubare Beschichtung besteht bevorzugt aus biodegradierbaren Polymeren und kann zudem mindestens eine pharmakologisch aktive Substanz wie beispielsweise einen antiinflammatorischen, cytostatischen, cytotoxischen, antiproliferativen, anti-mikrotubuli, antiangiogenen, antirestenotischen (anti-Restenose), antifungiziden, antineoplastischen, antimigrativen, athrombogenen und/oder antithrombogenen Wirkstoff enthalten.
PCT/DE2008/000160 2007-01-30 2008-01-30 Biologisch abbaubare gefässstütze WO2008092435A2 (de)

Priority Applications (11)

Application Number Priority Date Filing Date Title
PL08706826T PL2114481T3 (pl) 2007-01-30 2008-01-30 Biodegradowalny stent
ES08706826.8T ES2557170T3 (es) 2007-01-30 2008-01-30 Soporte vascular biodegradable
EP08706826.8A EP2114481B1 (de) 2007-01-30 2008-01-30 Biologisch abbaubare gefässstütze
CN200880003444.3A CN101636187B (zh) 2007-01-30 2008-01-30 生物可降解性血管支持器
AU2008210149A AU2008210149B2 (en) 2007-01-30 2008-01-30 Biodegradable vascular support
BRPI0807830A BRPI0807830B8 (pt) 2007-01-30 2008-01-30 stent biodegradável
MX2009008064A MX2009008064A (es) 2007-01-30 2008-01-30 Soporte vascular biodegradable.
JP2009547528A JP5391082B2 (ja) 2007-01-30 2008-01-30 生分解性血管支持体
US12/520,976 US20100076544A1 (en) 2007-01-30 2008-01-30 Biodegradable vascular support
CA2673914A CA2673914C (en) 2007-01-30 2008-01-30 Biodegradable vascular support
IL199569A IL199569A (en) 2007-01-30 2009-06-25 Supplies biodegradable

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE102007005474.4 2007-01-30
DE102007005474 2007-01-30
DE200710034350 DE102007034350A1 (de) 2007-07-24 2007-07-24 Biologisch abbaubare Gefäßstütze
DE102007034350.9 2007-07-24

Publications (3)

Publication Number Publication Date
WO2008092435A2 WO2008092435A2 (de) 2008-08-07
WO2008092435A3 true WO2008092435A3 (de) 2009-07-30
WO2008092435A9 WO2008092435A9 (de) 2009-10-15

Family

ID=39674532

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE2008/000160 WO2008092435A2 (de) 2007-01-30 2008-01-30 Biologisch abbaubare gefässstütze

Country Status (13)

Country Link
US (1) US20100076544A1 (de)
EP (1) EP2114481B1 (de)
JP (1) JP5391082B2 (de)
KR (1) KR20090122202A (de)
AU (1) AU2008210149B2 (de)
BR (1) BRPI0807830B8 (de)
CA (1) CA2673914C (de)
ES (1) ES2557170T3 (de)
IL (1) IL199569A (de)
MX (1) MX2009008064A (de)
PL (1) PL2114481T3 (de)
RU (1) RU2452517C2 (de)
WO (1) WO2008092435A2 (de)

Families Citing this family (81)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU2002345328A1 (en) 2001-06-27 2003-03-03 Remon Medical Technologies Ltd. Method and device for electrochemical formation of therapeutic species in vivo
US8840660B2 (en) 2006-01-05 2014-09-23 Boston Scientific Scimed, Inc. Bioerodible endoprostheses and methods of making the same
US8089029B2 (en) 2006-02-01 2012-01-03 Boston Scientific Scimed, Inc. Bioabsorbable metal medical device and method of manufacture
US8048150B2 (en) 2006-04-12 2011-11-01 Boston Scientific Scimed, Inc. Endoprosthesis having a fiber meshwork disposed thereon
JP2009545407A (ja) 2006-08-02 2009-12-24 ボストン サイエンティフィック サイムド，インコーポレイテッド 三次元分解制御を備えたエンドプロテーゼ
US8808726B2 (en) 2006-09-15 2014-08-19 Boston Scientific Scimed. Inc. Bioerodible endoprostheses and methods of making the same
ATE517590T1 (de) 2006-09-15 2011-08-15 Boston Scient Ltd Biologisch erodierbare endoprothesen
ES2368125T3 (es) * 2006-09-15 2011-11-14 Boston Scientific Scimed, Inc. Endoprótesis bioerosionable con capas inorgánicas bioestables.
JP2010503485A (ja) 2006-09-15 2010-02-04 ボストン サイエンティフィック リミテッド 医療用デバイスおよび同デバイスの製造方法
US8002821B2 (en) 2006-09-18 2011-08-23 Boston Scientific Scimed, Inc. Bioerodible metallic ENDOPROSTHESES
ATE488259T1 (de) 2006-12-28 2010-12-15 Boston Scient Ltd Bioerodierbare endoprothesen und herstellungsverfahren dafür
DE102007038799A1 (de) * 2007-08-17 2009-02-19 Biotronik Vi Patent Ag Implantat aus einer biokorrodierbaren Magnesiumlegierung und mit einer Beschichtung aus einem biokorrodierbaren Polyphosphazen
US8052745B2 (en) 2007-09-13 2011-11-08 Boston Scientific Scimed, Inc. Endoprosthesis
WO2009102787A2 (en) * 2008-02-12 2009-08-20 Boston Scientific Scimed, Inc. Medical implants with polysaccharide drug eluting coatings
WO2009113605A1 (ja) * 2008-03-12 2009-09-17 アンジェスＭｇ株式会社 薬剤溶出型カテーテル及びその製造方法
DE102008020415A1 (de) * 2008-04-24 2009-10-29 Biotronik Vi Patent Ag Biodegradierbare metallische Stents mit Wachsschicht
US7998192B2 (en) 2008-05-09 2011-08-16 Boston Scientific Scimed, Inc. Endoprostheses
US8236046B2 (en) 2008-06-10 2012-08-07 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US7985252B2 (en) 2008-07-30 2011-07-26 Boston Scientific Scimed, Inc. Bioerodible endoprosthesis
US9119906B2 (en) * 2008-09-24 2015-09-01 Integran Technologies, Inc. In-vivo biodegradable medical implant
US8382824B2 (en) 2008-10-03 2013-02-26 Boston Scientific Scimed, Inc. Medical implant having NANO-crystal grains with barrier layers of metal nitrides or fluorides
DE102008043277A1 (de) * 2008-10-29 2010-05-06 Biotronik Vi Patent Ag Implantat aus einer biokorrodierbaren Eisen- oder Magnesiumlegierung
US8735354B2 (en) * 2008-11-07 2014-05-27 Uab Research Foundation Endothelium mimicking nanomatrix
US9283304B2 (en) * 2008-11-25 2016-03-15 CARDINAL HEALTH SWITZERLAND 515 GmbH Absorbable stent having a coating for controlling degradation of the stent and maintaining pH neutrality
EP2403546A2 (de) 2009-03-02 2012-01-11 Boston Scientific Scimed, Inc. Selbstpufferende medizinische implantate
US8435281B2 (en) 2009-04-10 2013-05-07 Boston Scientific Scimed, Inc. Bioerodible, implantable medical devices incorporating supersaturated magnesium alloys
AU2010249558A1 (en) * 2009-05-20 2011-12-08 Arsenal Medical, Inc. Medical implant
US20110319987A1 (en) * 2009-05-20 2011-12-29 Arsenal Medical Medical implant
US9265633B2 (en) 2009-05-20 2016-02-23 480 Biomedical, Inc. Drug-eluting medical implants
US8888840B2 (en) * 2009-05-20 2014-11-18 Boston Scientific Scimed, Inc. Drug eluting medical implant
US8252022B2 (en) * 2009-07-13 2012-08-28 Vascular Solutions, Inc. Metal vascular aperture closure device
US20130131814A1 (en) * 2009-12-07 2013-05-23 Ja-Kyo Koo Implant
EP2338536B1 (de) * 2009-12-21 2015-08-05 Biotronik VI Patent AG Biokorrodierbare Implantate mit funktionalisierter Beschichtung
US8668732B2 (en) 2010-03-23 2014-03-11 Boston Scientific Scimed, Inc. Surface treated bioerodible metal endoprostheses
US10292808B2 (en) 2010-06-07 2019-05-21 Q3 Medical Devices Limited Device and method for management of aneurism, perforation and other vascular abnormalities
EP2399620B1 (de) 2010-06-28 2016-08-10 Biotronik AG Implantat und Verfahren zur Herstellung desselben
CN102371006B (zh) * 2010-08-17 2014-08-20 上海微创医疗器械（集团）有限公司 一种生物可降解支架
EP2624834A4 (de) * 2010-10-04 2014-09-17 Elixir Medical Corp Makrocyclische lactonverbindungen und verfahren zu ihrer verwendung
US20120150282A1 (en) * 2010-12-10 2012-06-14 Biotronik Ag Implant having a paclitaxel-releasing coating
TWI548427B (zh) 2010-12-21 2016-09-11 星瑟斯有限公司 含有生物可降解鎂系合金之醫療植入物及其製造方法
RU2642254C2 (ru) * 2011-08-15 2018-01-24 Меко Лазерштраль-Материальбеарбайтунген Е.К. Рассасывающие стенты, которые содержат магниевые сплавы
SG11201402789TA (en) * 2012-01-23 2014-09-26 Cortronik GmbH Device for coating a stent, corresponding coating method, and stent produced according to said method
EP2630978B1 (de) * 2012-02-22 2018-10-31 Biotronik AG Implantat und verfahren zur herstellung desselben
CN107198792A (zh) * 2012-03-09 2017-09-26 Q3 医疗设备有限公司 生物可降解的支撑装置
US8834902B2 (en) 2012-03-09 2014-09-16 Q3 Medical Devices Limited Biodegradable supporting device
US9333099B2 (en) * 2012-03-30 2016-05-10 Abbott Cardiovascular Systems Inc. Magnesium alloy implants with controlled degradation
RU2519103C2 (ru) * 2012-08-13 2014-06-10 Федеральное государственное бюджетное учреждение "Научный центр сердечно-сосудистой хирургии имени А.Н. Бакулева" Российской академии медицинских наук Биорезорбируемая гидрогелевая полимерная композиция с биологически активными веществами (варианты)
US9700441B2 (en) * 2012-10-31 2017-07-11 W. L. Gore & Associates, Inc. Devices and methods related to deposited support structures
US10959715B2 (en) 2012-10-31 2021-03-30 W. L. Gore & Associates, Inc. Devices and methods related to deposited support structures
US11744594B2 (en) 2012-11-16 2023-09-05 W.L. Gore & Associates, Inc. Space filling devices
KR101461162B1 (ko) * 2013-01-29 2014-11-13 서울대학교산학협력단 접착성 물질을 이용하여 신체 이식 후 이동을 최소화하는 스텐트 및 방법
EP2767295B1 (de) 2013-02-13 2015-11-04 Biotronik AG Biokorrodierbares Implantat mit korrosionshemmender Beschichtung
EP2767294B1 (de) 2013-02-13 2018-03-21 Biotronik AG Biokorrodierbares Implantat mit korrosionshemmender Beschichtung
KR101722036B1 (ko) * 2013-12-26 2017-03-31 주식회사 삼양바이오팜 약물 방출 조절형 생분해성 스텐트용 약물 코팅제 및 그 제조방법, 및 이 코팅제로 코팅된 생분해성 스텐트 및 그 제조방법
CN103736152B (zh) * 2013-12-26 2016-12-07 西安爱德万思医疗科技有限公司 一种人体可吸收的耐蚀高强韧锌合金植入材料
JP2015180247A (ja) * 2014-03-03 2015-10-15 国立大学法人 岡山大学 薬剤放出層を有するインプラント
WO2015147183A1 (ja) * 2014-03-28 2015-10-01 古河電気工業株式会社 亜鉛合金管材とその製造方法、及びそれを用いてなるステントとその製造方法
CA2947494C (en) * 2014-05-02 2020-10-20 Research Institute At Nationwide Children's Hospital Compositions and methods for anti-lyst immunomodulation
WO2015171911A1 (en) * 2014-05-09 2015-11-12 Mayo Foundation For Medical Education And Research Devices and methods for forming stents in vivo
RU2551938C1 (ru) * 2014-07-14 2015-06-10 Общество с ограниченной ответственностью "Инновационная компания "Современные технологии" Многоцелевой сосудистый имплант
CN105797220B (zh) * 2014-12-31 2020-07-31 先健科技(深圳)有限公司 可降解铁基合金支架
KR102515652B1 (ko) 2015-02-20 2023-03-30 쓰리엠 이노베이티브 프로퍼티즈 캄파니 감압 접착제 함유 물품을 위한 이형 층으로서의 실리콘 카르보네이트 중합체
KR20160122948A (ko) * 2015-04-14 2016-10-25 주식회사 바이오알파 생체 내 생분해 속도가 조절된 생분해성 스텐트 및 이의 제조 방법
US11541149B2 (en) 2015-12-11 2023-01-03 Research Institute At Nationwide Children's Hospital Systems and methods for optimized patient specific tissue engineering vascular grafts
CN106902395B (zh) 2015-12-22 2020-04-07 先健科技(深圳)有限公司 可吸收铁基合金植入医疗器械
CN106955374B (zh) * 2016-01-08 2019-11-08 先健科技(深圳)有限公司 植入式器械
EP3463205A4 (de) * 2016-05-25 2020-01-08 Q3 Medical Devices Limited Biologisch abbaubare tragevorrichtung
CZ309165B6 (cs) * 2016-10-20 2022-04-06 Ústav Struktury A Mechaniky Hornin Av Čr, V. V. I. Příprava nanokompozitní vrstvy na bázi kolagenových nanovláken
JP2018196401A (ja) * 2017-05-19 2018-12-13 ロレアル マイクロニードルシート
SE545102C2 (en) 2018-04-25 2023-04-04 Bactiguard Ab A surface coating for use in the prophylaxis of allergy
KR102302544B1 (ko) * 2019-03-26 2021-09-15 형태경 스텐트 제조용 생분해성 수지 조성물
US11806257B2 (en) 2019-07-09 2023-11-07 Otsuka Medical Devices Co., Ltd. Drug-eluting stent including crystalline cilostazol
RU2725644C1 (ru) * 2019-12-11 2020-07-03 Федеральное государственное бюджетное образовательное учреждение высшего образования "Московский государственный университет пищевых производств" Биодеградируемая полимерная композиция с антимикробными свойствами на основе полиолефинов
RU2733708C1 (ru) * 2020-01-31 2020-10-06 Общество с ограниченной ответственностью «ЦЕНТР НОВЫХ МАТЕРИАЛОВ» Способ получения композиционного биомедицинского материала «никелид титана-полилактид» с возможностью контролируемой доставки лекарственных средств
CN111494794B (zh) * 2020-05-08 2021-12-28 山东百多安医疗器械股份有限公司 一种具有调节血管功能的锌合金支架系统
RU2741986C1 (ru) * 2020-05-12 2021-02-01 Федеральное государственное бюджетное образовательное учреждение высшего образования "Кабардино-Балкарский государственный университет им. Х.М. Бербекова" (КБГУ) Биоразлагаемый материал
DE202021100450U1 (de) * 2021-01-29 2021-02-18 Biotronik Ag Schnell resorbierbares intravaskuläres Implantat
DE102021103786B4 (de) * 2021-02-17 2023-07-20 Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung eingetragener Verein Implantat zum Implantieren in einen Organismus und Verfahren
CN113142015B (zh) * 2021-04-22 2022-03-04 西南科技大学 一种天然砂石浆洗淤泥制备有机营养土的方法
CN114522253B (zh) * 2021-12-24 2023-05-26 重庆医科大学附属第二医院 多功能纳米粒及其制备方法、应用
CN115337463B (zh) * 2022-04-18 2023-10-13 东南大学 一种双载药微球-静电纺丝覆膜支架的制备方法及应用

Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050209680A1 (en) * 1997-04-15 2005-09-22 Gale David C Polymer and metal composite implantable medical devices
WO2006060033A1 (en) * 2004-05-20 2006-06-08 Boston Scientific Limited Medical devices and methods of making the same
WO2006108065A2 (en) * 2005-04-05 2006-10-12 Elixir Medical Corporation Degradable implantable medical devices
DE102005018356A1 (de) * 2005-04-20 2006-10-26 Orlowski, Michael, Dr. Resorbierbare Implantate
WO2006116989A2 (de) * 2005-05-05 2006-11-09 Hemoteq Ag Vollflächige beschichtung von gefässstützen
US20060271168A1 (en) * 2002-10-30 2006-11-30 Klaus Kleine Degradable medical device
WO2007005806A1 (en) * 2005-06-30 2007-01-11 Advanced Cardiovascular Systems, Inc. Coatings for controlling erosion of a substrate of an implantable medical device
EP1891996A2 (de) * 2006-08-07 2008-02-27 BIOTRONIK VI Patent AG Verbesserung der Stabilität biodegradierbarer metallischer Stents, Verfahren und Verwendungen
EP1891992A2 (de) * 2006-08-07 2008-02-27 BIOTRONIK VI Patent AG Biodegradierbarer Stent mit einer aktiven Beschichtung
WO2008076582A2 (en) * 2006-12-15 2008-06-26 Medtronic Vascular Inc. Bioresorbable stent

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6240616B1 (en) * 1997-04-15 2001-06-05 Advanced Cardiovascular Systems, Inc. Method of manufacturing a medicated porous metal prosthesis
DE10253634A1 (de) 2002-11-13 2004-05-27 Biotronik Meß- und Therapiegeräte GmbH & Co. Ingenieurbüro Berlin Endoprothese
US7758892B1 (en) * 2004-05-20 2010-07-20 Boston Scientific Scimed, Inc. Medical devices having multiple layers
DE102006038241A1 (de) * 2006-08-07 2008-02-14 Biotronik Vi Patent Ag Stent mit einer genisteinhaltigen Beschichtung oder Kavitätenfüllung

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050209680A1 (en) * 1997-04-15 2005-09-22 Gale David C Polymer and metal composite implantable medical devices
US20060271168A1 (en) * 2002-10-30 2006-11-30 Klaus Kleine Degradable medical device
WO2006060033A1 (en) * 2004-05-20 2006-06-08 Boston Scientific Limited Medical devices and methods of making the same
WO2006108065A2 (en) * 2005-04-05 2006-10-12 Elixir Medical Corporation Degradable implantable medical devices
DE102005018356A1 (de) * 2005-04-20 2006-10-26 Orlowski, Michael, Dr. Resorbierbare Implantate
WO2006116989A2 (de) * 2005-05-05 2006-11-09 Hemoteq Ag Vollflächige beschichtung von gefässstützen
WO2007005806A1 (en) * 2005-06-30 2007-01-11 Advanced Cardiovascular Systems, Inc. Coatings for controlling erosion of a substrate of an implantable medical device
EP1891996A2 (de) * 2006-08-07 2008-02-27 BIOTRONIK VI Patent AG Verbesserung der Stabilität biodegradierbarer metallischer Stents, Verfahren und Verwendungen
EP1891992A2 (de) * 2006-08-07 2008-02-27 BIOTRONIK VI Patent AG Biodegradierbarer Stent mit einer aktiven Beschichtung
WO2008076582A2 (en) * 2006-12-15 2008-06-26 Medtronic Vascular Inc. Bioresorbable stent

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CA2673914C (en) 2013-10-08
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MX2009008064A (es) 2009-08-07
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IL199569A (en) 2014-02-27
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CA2673914A1 (en) 2008-08-07
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