WO2008103997A3 - Needle-free injection devices and drug delivery systems therefor - Google Patents

Needle-free injection devices and drug delivery systems therefor Download PDF

Info

Publication number
WO2008103997A3
WO2008103997A3 PCT/US2008/054917 US2008054917W WO2008103997A3 WO 2008103997 A3 WO2008103997 A3 WO 2008103997A3 US 2008054917 W US2008054917 W US 2008054917W WO 2008103997 A3 WO2008103997 A3 WO 2008103997A3
Authority
WO
WIPO (PCT)
Prior art keywords
needle
injection
drug delivery
chamber
free
Prior art date
Application number
PCT/US2008/054917
Other languages
French (fr)
Other versions
WO2008103997A2 (en
Inventor
Sergio Landau
Daniel E Williamson
Original Assignee
Bioject Inc
Sergio Landau
Daniel E Williamson
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bioject Inc, Sergio Landau, Daniel E Williamson filed Critical Bioject Inc
Publication of WO2008103997A2 publication Critical patent/WO2008103997A2/en
Publication of WO2008103997A3 publication Critical patent/WO2008103997A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M5/2053—Media being expelled from injector by pressurised fluid or vacuum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/202—Separating means
    • A61J1/2044—Separating means having slits
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2096—Combination of a vial and a syringe for transferring or mixing their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • A61M2005/2006—Having specific accessories
    • A61M2005/2013—Having specific accessories triggering of discharging means by contact of injector with patient body
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/002—Packages specially adapted therefor, e.g. for syringes or needles, kits for diabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/1782—Devices aiding filling of syringes in situ

Abstract

Needle-free injection devices and drug delivery systems are disclosed. The needle-free injection devices may include a drug delivery system, a power source, an activation system, and a disabling element. The drug delivery system may include a needle-free syringe and a drug storage system. The needle-free syringe may include a plunger slidably disposed within an injection chamber. The injection chamber may include an injection orifice, and the plunger may be configured to expel a volume of fluid from the injection chamber through the injection orifice. The drug storage system may include a storage chamber and an outlet. The drug storage system may be frangibly connected to the needle-free syringe with the outlet proximate to and fluidly connected with the injection orifice. The drug storage system may be configured to inject a fluid from the storage chamber through the outlet, through the injection orifice, and into the injection chamber.
PCT/US2008/054917 2007-02-23 2008-02-25 Needle-free injection devices and drug delivery systems therefor WO2008103997A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US89146607P 2007-02-23 2007-02-23
US60/891,466 2007-02-23

Publications (2)

Publication Number Publication Date
WO2008103997A2 WO2008103997A2 (en) 2008-08-28
WO2008103997A3 true WO2008103997A3 (en) 2008-10-23

Family

ID=39710800

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/054917 WO2008103997A2 (en) 2007-02-23 2008-02-25 Needle-free injection devices and drug delivery systems therefor

Country Status (2)

Country Link
US (1) US7744563B2 (en)
WO (1) WO2008103997A2 (en)

Families Citing this family (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0100756D0 (en) 2001-01-11 2001-02-21 Powderject Res Ltd Needleless syringe
GB0708758D0 (en) 2007-05-04 2007-06-13 Powderject Res Ltd Particle cassettes and process thereof
DE102009004828B4 (en) * 2009-01-13 2010-12-09 Lts Lohmann Therapie-Systeme Ag Injector with displaceable plug part
DE102010019223B4 (en) * 2010-05-04 2012-02-16 Heraeus Medical Gmbh Cartridge system with compressed gas cartridge
AU2015255197B2 (en) * 2011-01-26 2019-03-28 Kaleo, Inc. Medicament delivery devices for administration of a medicament within a prefilled syringe
US9173999B2 (en) 2011-01-26 2015-11-03 Kaleo, Inc. Devices and methods for delivering medicaments from a multi-chamber container
WO2012135943A1 (en) * 2011-04-04 2012-10-11 Idee International R&D Inc. Safety syringe for needleless injector
DE102011077809A1 (en) 2011-06-20 2012-12-20 Charité - Universitätsmedizin Berlin Biocompatible adhesive and process for its preparation
JP6781040B2 (en) * 2013-05-03 2020-11-04 アルコン インコーポレイティド Gas syringe filling device and how to manufacture and use the device
GB2519971B (en) * 2013-11-01 2017-06-14 Consort Medical Plc Medicament delivery device sub-assembly
DE102015101126A1 (en) 2015-01-27 2016-07-28 Heraeus Medical Gmbh Paste application device for mixing a paste of two components
AU2016219904B2 (en) 2015-02-20 2020-07-02 Regeneron Pharmaceuticals, Inc. Syringe systems, piston seal systems, stopper systems, and methods of use and assembly
CA2990950A1 (en) 2015-06-30 2017-01-05 Kaleo, Inc. Auto-injectors for administration of a medicament within a prefilled syringe
DE102015117270A1 (en) 2015-10-09 2017-04-13 Heraeus Medical Gmbh Paste application device for mixing a paste
WO2017181325A1 (en) * 2016-04-18 2017-10-26 Medtrum Technologies Inc. Multi-mode power supply system for a portable infusion device
FR3057169B1 (en) * 2016-10-11 2022-04-01 Crossject INJECTION NOZZLE FOR NEEDLELESS INJECTION DEVICE
WO2018119218A1 (en) 2016-12-23 2018-06-28 Kaleo, Inc. Medicament delivery device and methods for delivering drugs to infants and children
BR112020007429B1 (en) * 2017-10-16 2023-11-07 Enable Injections, Inc TRANSFER DEVICE FOR TRANSFERRING A MEDICAL FLUID FROM A VIAL TO A MEDICAL FLUID INJECTION DEVICE
CN111417423B (en) * 2017-11-04 2022-10-11 奥特威资有限责任公司 Injection device and methods of making and using the same
US11890453B2 (en) * 2017-11-04 2024-02-06 Altaviz, Llc Injection devices and methods for making and using them
KR101907552B1 (en) * 2018-05-03 2018-10-12 주식회사 피테크 Painless injection device without needle
EP3627034B1 (en) * 2018-09-21 2021-10-27 Goodrich Corporation Valve
US20220000717A1 (en) * 2018-10-04 2022-01-06 Daicel Corporation Adapter and injection fluid transfer method
US11224537B2 (en) 2018-10-19 2022-01-18 Alcon Inc. Intraocular gas injector
WO2021030210A1 (en) 2019-08-09 2021-02-18 Kaleo, Inc. Devices and methods for delivery of substances within a prefilled syringe

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6223786B1 (en) * 1998-11-14 2001-05-01 Pen Jet Corporation Apparatus and method for mixing medication and filling an ampule of a needle-less injector
US20030097093A1 (en) * 2000-05-30 2003-05-22 Alain Navelier Needleless syringe with membrane isolating a multiple duct injector
US6607510B2 (en) * 2001-11-09 2003-08-19 Bioject Medical Technologies Inc. Disposable needle-free injection apparatus and method
US20030187386A1 (en) * 2000-04-07 2003-10-02 Parsons J. Stuart Low cost disposable needleless injector system for variable and fixed dose applications
US6682504B2 (en) * 2000-03-23 2004-01-27 Antares Pharma, Inc. Single use disposable jet injector
US20050192530A1 (en) * 2001-04-13 2005-09-01 Penjet Corporation Method and apparatus for needle-less injection with a degassed fluid
US20060089594A1 (en) * 2004-10-26 2006-04-27 Sergio Landau Needle-free injection device

Family Cites Families (154)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL133435C (en) 1900-01-01
US2545017A (en) 1947-06-02 1951-03-13 Gordon D Billingsley Hypodermic syringe
US2582818A (en) 1948-04-13 1952-01-15 United Products Co Inc Method of manufacturing glass ampoules
US2680439A (en) 1948-09-08 1954-06-08 Arnold K Sutermeister High-pressure injection device
US2653602A (en) 1950-06-17 1953-09-29 Becton Dickinson Co Injection device
US2667874A (en) 1951-07-09 1954-02-02 Becton Dickinson Co Medicament cartridge assembly
US3110309A (en) 1960-08-15 1963-11-12 Brunswick Corp Plastic cartridge needle assembly
US3115133A (en) 1962-05-15 1963-12-24 Morando Emilio Donald Needleless prefilled disposable hypodermic injector
US3202151A (en) 1963-04-08 1965-08-24 Scherer Corp R P Multidose jet injector
US3292621A (en) 1963-07-19 1966-12-20 Oscar H Banker Jet type protable inoculator
US3552083A (en) 1965-04-14 1971-01-05 Andersen Prod H W Apparatus and method for storing and releasing a volatile substance
US3507276A (en) 1968-08-28 1970-04-21 Murray B Burgess Jet injector
US3561443A (en) 1968-09-06 1971-02-09 Oscar H Banker Inoculator gun with delayed action
US3688765A (en) 1969-10-03 1972-09-05 Jack S Gasaway Hypodermic injection device
US3695266A (en) 1970-06-18 1972-10-03 Maurice G Lussier Needleless sequential dosing syringe
US3941128A (en) 1970-11-10 1976-03-02 Affiliated Hospital Products, Inc. Fluid dispensing arrangement
US3714943A (en) 1970-12-01 1973-02-06 H Yanof Medicament injectors
US3853125A (en) 1971-10-05 1974-12-10 W Clark Disposable needleless injector
US3729031A (en) 1971-12-06 1973-04-24 Mpl Inc Liquid dispenser and plunger and method and apparatus for filling same
US3859996A (en) 1973-07-18 1975-01-14 Mizzy Inc Multi-dose injector
US3940003A (en) 1974-05-07 1976-02-24 Pharmaco, Inc. Safety cap for medicament vial having puncturable seal
US3945379A (en) 1974-08-08 1976-03-23 Smithkline Corporation Injection device
JPS51130094A (en) 1975-05-08 1976-11-12 Asahi Chemical Ind Twoostage pressure injector
US4124024A (en) 1977-03-03 1978-11-07 Schwebel Paul R Disposable hypodermic injection ampule
BR7806153A (en) 1978-09-19 1980-04-01 Halen Elliot Brasil Ind Com Eq HYPODERMIC PRESSURE INJECTOR FOR INTERMITTENT VACCINATION
US4447225A (en) 1982-03-22 1984-05-08 Taff Barry E Multidose jet injector
US4479801A (en) 1982-06-25 1984-10-30 Cohen Milton J Fluid dispensing device
IT1195615B (en) 1983-01-24 1988-10-19 Mario Geat TTANCUTANEO INJECTOR DEVICE
US4592745A (en) 1984-02-29 1986-06-03 Novo Industri A/S Dispenser
US4652261A (en) 1984-06-22 1987-03-24 Regents Of The University Of Minnesota Drug-injection animal capture collar
US4596556A (en) 1985-03-25 1986-06-24 Bioject, Inc. Hypodermic injection apparatus
US4662878A (en) 1985-11-13 1987-05-05 Patents Unlimited Ltd. Medicine vial adaptor for needleless injector
US4680027A (en) * 1985-12-12 1987-07-14 Injet Medical Products, Inc. Needleless hypodermic injection device
EP0250022A3 (en) 1986-06-17 1988-06-22 SICIM SpA Portable endermic injector
US4713061A (en) 1986-07-14 1987-12-15 Survival Technology, Inc. Cartridge with universal plastic hub
US4747839A (en) 1986-12-17 1988-05-31 Survival Technology, Inc. Disposable hypodermic syringe with plastic snap-on needle hub and heat shrink seal therefor
US4717384A (en) 1987-01-15 1988-01-05 Pneu Dart Inc. Pneumatic hypodermic syringe pole
US4886495A (en) 1987-07-08 1989-12-12 Duoject Medical Systems Inc. Vial-based prefilled syringe system for one or two component medicaments
US5080648A (en) 1987-06-08 1992-01-14 Antonio Nicholas F D Hypodermic fluid dispenser
US5569190A (en) 1987-06-08 1996-10-29 D'antonio; Nicholas F. Hypodermic fluid dispenser
US6056716A (en) 1987-06-08 2000-05-02 D'antonio Consultants International Inc. Hypodermic fluid dispenser
US4941880A (en) 1987-06-19 1990-07-17 Bioject, Inc. Pre-filled ampule and non-invasive hypodermic injection device assembly
US4790824A (en) 1987-06-19 1988-12-13 Bioject, Inc. Non-invasive hypodermic injection device
US4940460A (en) 1987-06-19 1990-07-10 Bioject, Inc. Patient-fillable and non-invasive hypodermic injection device assembly
AU628029B2 (en) 1987-11-16 1992-09-10 Sy-Quest International Limited Improved apparatus for hypodermic injection of liquids
AU595096B2 (en) 1988-02-10 1990-03-22 Astra Pharmaceuticals Pty Ltd Plastic cartridge and syringe
US4913699A (en) * 1988-03-14 1990-04-03 Parsons James S Disposable needleless injection system
US4909794A (en) 1988-06-24 1990-03-20 Habley Medical Technology Corporation Combination retractable needle cannula and cannula lock for a medication carpule
US5024656A (en) 1988-08-30 1991-06-18 Injet Medical Products, Inc. Gas-pressure-regulated needleless injection system
US5312335A (en) 1989-11-09 1994-05-17 Bioject Inc. Needleless hypodermic injection device
US5064413A (en) 1989-11-09 1991-11-12 Bioject, Inc. Needleless hypodermic injection device
AU6550990A (en) 1989-11-09 1991-05-16 Bioject, Inc. Needleless hypodermic injection device
US5049128A (en) 1990-02-06 1991-09-17 Duquette Irene A Valved infusion port
US5171214A (en) 1990-12-26 1992-12-15 Abbott Laboratories Drug storage and delivery system
US5181909A (en) 1991-05-15 1993-01-26 Mcfarlane Richard H Ampule-container medical syringe and methods
US5179024A (en) 1991-05-30 1993-01-12 Harald Dahms Sealed vials containing improved karl fischer solutions, and process for water determination using these vials
EP0518416A1 (en) 1991-06-13 1992-12-16 Duphar International Research B.V Injection device
DK134691D0 (en) 1991-07-12 1991-07-12 Novo Nordisk As APPARATUS
US6623449B2 (en) 1991-07-15 2003-09-23 Larry D. Paskar Catheter with up-going and down-going configurations
GB9118204D0 (en) 1991-08-23 1991-10-09 Weston Terence E Needle-less injector
US5306277A (en) 1991-12-23 1994-04-26 Zimmer, Inc. Monomer transfer device
GB9212742D0 (en) 1992-06-16 1992-07-29 Sterimatic Holdings Ltd Syringe or blood collection system
US5383851A (en) 1992-07-24 1995-01-24 Bioject Inc. Needleless hypodermic injection device
US5254086A (en) * 1992-07-31 1993-10-19 Ballard Medical Products Medical lavage apparatus and methods
WO1994006690A1 (en) 1992-09-21 1994-03-31 Habley Medical Technology Corporation Device and method for containing an ampule and transferring liquid within the ampule to a container
AU5293393A (en) 1992-09-28 1994-04-26 Equidyne Systems, Incorporated Hypodermic jet injector
US5569189A (en) 1992-09-28 1996-10-29 Equidyne Systems, Inc. hypodermic jet injector
US5334144A (en) 1992-10-30 1994-08-02 Becton, Dickinson And Company Single use disposable needleless injector
US5405333A (en) 1992-12-28 1995-04-11 Richmond; Frank M. Liquid medicament bag with needleless connector fitting using boat assembly
US5746714A (en) 1993-04-05 1998-05-05 P.A.T.H. Air powered needleless hypodermic injector
TW360548B (en) 1993-04-08 1999-06-11 Powderject Res Ltd Products for therapeutic use
US5364386A (en) 1993-05-05 1994-11-15 Hikari Seiyaku Kabushiki Kaisha Infusion unit
US5453096A (en) 1993-07-26 1995-09-26 Merck & Co., Inc. Device for the distribution of successive doses of a fluid product-in particular medicinal or cosmetic-contained in a vial
JP3487856B2 (en) 1993-07-31 2004-01-19 ウェストン メディカル リミテッド Needleless syringe
US5472022A (en) 1993-11-02 1995-12-05 Genentech, Inc. Injection pen solution transfer apparatus and method
US5505697A (en) 1994-01-14 1996-04-09 Mckinnon, Jr.; Charles N. Electrically powered jet injector
US6681810B2 (en) 1994-12-20 2004-01-27 Aradigm Corporation Filling device for a needleless injector cartridge
GB9425642D0 (en) 1994-12-20 1995-02-22 Weston Medical Ltd Filling device
US5599302A (en) 1995-01-09 1997-02-04 Medi-Ject Corporation Medical injection system and method, gas spring thereof and launching device using gas spring
GB9504878D0 (en) 1995-03-10 1995-04-26 Weston Medical Ltd Viscously coupled actuator
US5503628A (en) 1995-03-15 1996-04-02 Jettek, Inc. Patient-fillable hypodermic jet injector
US5730723A (en) 1995-10-10 1998-03-24 Visionary Medical Products Corporation, Inc. Gas pressured needle-less injection device and method
FR2739562B1 (en) 1995-10-09 1998-04-24 Moreau Defarges Alain JET INJECTION DEVICE WITHOUT NEEDLE, INCLUDING AN OVER-MOLDED CARTRIDGE
US6080130A (en) 1998-11-14 2000-06-27 Castellano; Thomas P. Gas power source for a needle-less injector
US5716348A (en) 1995-10-19 1998-02-10 Meridian Medical Technologies, Inc. Anti-coring needle
US20010004682A1 (en) 1995-12-16 2001-06-21 Weston Medical Ltd. Needleless injector drug capsule
GB9525757D0 (en) 1995-12-16 1996-02-14 Weston Medical Ltd Needleless injector drug capsule and filling method
US5893397A (en) 1996-01-12 1999-04-13 Bioject Inc. Medication vial/syringe liquid-transfer apparatus
GB9602605D0 (en) 1996-02-09 1996-04-10 Weston Medical Ltd Injection aid
US5921967A (en) 1996-02-29 1999-07-13 Medi-Ject Corporation Plunger for nozzle assembly
US5865795A (en) 1996-02-29 1999-02-02 Medi-Ject Corporation Safety mechanism for injection devices
US5782802A (en) 1996-03-22 1998-07-21 Vitajet Corporation Multiple use needle-less hypodermic injection device for individual users
US5769138A (en) 1996-04-01 1998-06-23 Medi-Ject Corporation Nozzle and adapter for loading medicament into an injector
HUP9902128A3 (en) 1996-04-02 2000-01-28 Weston Medical Ltd Eye Method filling a drug capsule and article produced thereby
GB9607549D0 (en) 1996-04-11 1996-06-12 Weston Medical Ltd Spring-powered dispensing device
NL1004059C2 (en) 1996-09-18 1998-03-19 Plastic Moulding Appliances B Assembly of container and snap closure and method for the manufacture thereof.
EP0932424B1 (en) * 1996-09-25 2002-06-19 Weston Medical Limited Method and apparatus for making an article from a formable material
SE9604162D0 (en) 1996-11-13 1996-11-13 Astra Ab membrane
US6251099B1 (en) 1996-11-27 2001-06-26 The General Hospital Corporation Compound delivery using impulse transients
US6258059B1 (en) 1997-02-06 2001-07-10 Weston Medical Limited Injection aid
US6179583B1 (en) 1997-02-25 2001-01-30 Weston Medical Limited Metered fluid delivery device
US5938637A (en) 1997-03-14 1999-08-17 Path Single-use medicine delivery unit for needleless hypodermic injector
US5993412A (en) 1997-05-19 1999-11-30 Bioject, Inc. Injection apparatus
US5911703A (en) 1997-05-22 1999-06-15 Avant Drug Delivery Systems, Inc. Two-stage fluid medicament jet injector
EP0888790A1 (en) 1997-07-04 1999-01-07 PowderJect Research Limited Drug particle delivery device
US6156008A (en) 1998-05-04 2000-12-05 Castellano; Thomas P. Device for avoiding subdermal hematomas from an injection
GB9818110D0 (en) 1998-08-19 1998-10-14 Weston Medical Ltd Needleless injectors and other devices
GB9819962D0 (en) 1998-09-15 1998-11-04 Weston Medical Ltd Needleless injection cartridge
US6264629B1 (en) 1998-11-18 2001-07-24 Bioject, Inc. Single-use needle-less hypodermic jet injection apparatus and method
US6096002A (en) 1998-11-18 2000-08-01 Bioject, Inc. NGAS powered self-resetting needle-less hypodermic jet injection apparatus and method
US6689093B2 (en) 1998-11-18 2004-02-10 Bioject, Inc. Single-use needle-less hypodermic jet injection apparatus and method
US6783509B1 (en) 1998-11-18 2004-08-31 Bioject Inc. Single-use needle-less hypodermic jet injection apparatus and method
US6132395A (en) 1998-12-08 2000-10-17 Bioject, Inc. Needleless syringe with prefilled cartridge
US6383168B1 (en) 1998-12-08 2002-05-07 Bioject Medical Technologies Inc. Needleless syringe with prefilled cartridge
US6406455B1 (en) 1998-12-18 2002-06-18 Biovalve Technologies, Inc. Injection devices
FR2796291B1 (en) 1999-07-16 2001-09-21 Cross Site Technologies NEEDLELESS SYRINGE WITH PIEZO-ELECTRICAL TRIGGERING SYSTEM
FR2796288B1 (en) 1999-07-16 2001-08-10 Cross Site Technologies NEEDLELESS SYRINGE WITH FITTED ELEMENT INJECTOR
FR2796289B1 (en) 1999-07-16 2001-08-10 Cross Site Technologies NEEDLELESS SYRINGE WITH SUPERIMPOSED ELEMENT INJECTOR
US6319224B1 (en) 1999-08-20 2001-11-20 Bioject Medical Technologies Inc. Intradermal injection system for injecting DNA-based injectables into humans
US6224567B1 (en) 1999-09-08 2001-05-01 Cambridge Biostability Limited Modified disposable injector device
FR2799374B1 (en) 1999-10-08 2001-12-07 Cross Site Technologies NEEDLELESS SYRINGE WITH FRICTION TRIGGER
FR2800619B1 (en) 1999-11-05 2002-02-08 Cross Site Technologies NEEDLELESS SYRINGE WITH TEMPORARILY RETAINED PUSHING MEDIA
FR2802102B1 (en) 1999-12-08 2002-07-12 Poudres & Explosifs Ste Nale NEEDLELESS SYRINGE WITH CONSTANT SECTION EJECTION TUBE
FR2802103B1 (en) 1999-12-08 2003-10-03 Poudres & Explosifs Ste Nale SYRINGE WITHOUT NEEDLE OPERATING WITH DRIVE OF THE ACTIVE PRINCIPLE BY IMPACT TUBE
FR2802820B1 (en) 1999-12-27 2002-10-18 Poudres & Explosifs Ste Nale SYRINGE WITHOUT NEEDLE FUNCTIONING BY IMPACT TUBE, WITH PREVIOUS HOLDING OF THE ACTIVE INGREDIENT ON THE SIDE
WO2001051109A1 (en) 2000-01-07 2001-07-19 Biovalve Technologies, Inc. Injection device
US6210359B1 (en) 2000-01-21 2001-04-03 Jet Medica, L.L.C. Needleless syringe
FR2804329B1 (en) 2000-02-02 2002-12-13 Poudres & Explosifs Ste Nale SYRINGE WITHOUT NEEDLE PROVIDED WITH A LID CONTAINING THE ACTIVE INGREDIENT
FR2804869B1 (en) 2000-02-11 2002-05-17 Poudres & Explosifs Ste Nale NEEDLELESS SYRINGE FOR THE INJECTION OF A LIQUID CONTAINED IN A PRE-FILLED BULB
FR2805749B1 (en) 2000-03-01 2002-05-17 Poudres & Explosifs Ste Nale NEEDLELESS SYRINGE AT TWO LEVELS OF INJECTION SPEED
FR2807946B1 (en) 2000-04-19 2002-06-07 Poudres & Explosifs Ste Nale NEEDLELESS SYRINGE OPERATING WITH A TWO-COMPOSITION PYROTECHNIC LOAD
US6716190B1 (en) 2000-04-19 2004-04-06 Scimed Life Systems, Inc. Device and methods for the delivery and injection of therapeutic and diagnostic agents to a target site within a body
FR2815544B1 (en) 2000-10-23 2003-02-14 Poudres & Explosifs Ste Nale SAFETY NEEDLE SYRINGE WITH COMPACT ARCHITECTURE
US6652483B2 (en) 2000-11-07 2003-11-25 Avant Drug Delivery Systems, Inc. Needleless jet injector system with separate drug reservoir
EP1339442A4 (en) 2000-11-30 2006-12-27 Biovalve Technologies Inc Injection systems
EP2554196B1 (en) 2000-11-30 2018-10-17 Valeritas, Inc. Fluid delivery and measurement systems
US6471669B2 (en) 2001-03-05 2002-10-29 Bioject Medical Technologies Inc. Disposable needle-free injection apparatus and method
US6645170B2 (en) 2001-03-05 2003-11-11 Bioject Medical Technologies, Inc. Simplified disposable needle-free injection apparatus and method
US20020165499A1 (en) 2001-04-13 2002-11-07 Slate John B. Jet injector having a mechanism for creating air-in-tip
US6585685B2 (en) 2001-06-08 2003-07-01 Bioject Inc. Jet injector apparatus and method
US6752781B2 (en) 2001-06-08 2004-06-22 Sergio Landau Durable hypodermic jet injector apparatus and method
US6648850B2 (en) 2001-06-08 2003-11-18 Bioject, Inc. Durable needle-less jet injector apparatus and method
EP1434530A2 (en) 2001-10-12 2004-07-07 AMS Research Corporation Surgical instrument and method
GB0206560D0 (en) 2002-03-20 2002-05-01 Glaxo Group Ltd Novel device
US6676630B2 (en) 2002-06-04 2004-01-13 Bioject Medical Technologies, Inc. Needle-free injection system
US7156823B2 (en) 2002-06-04 2007-01-02 Bioject Inc. High workload needle-free injection system
US6883222B2 (en) 2002-10-16 2005-04-26 Bioject Inc. Drug cartridge assembly and method of manufacture
US6935384B2 (en) 2003-02-19 2005-08-30 Bioject Inc. Needle-free injection system
FR2852517B1 (en) 2003-03-21 2005-11-11 INJECTION DEVICE WITHOUT NEEDLE WITH PYROTECHNIC CARTRIDGE AND METHOD FOR ASSEMBLING SUCH A DEVICE
FR2852516B1 (en) 2003-03-21 2005-11-11 Crossject INJECTION DEVICE WITHOUT NEEDLE WITH MEANS FOR REGULATING THE LEVEL OF PRESSURE OF GASES IN THE COMBUSTION CHAMBER
FR2853837B1 (en) 2003-04-16 2006-01-13 Crossject DEVICE FOR CONNECTING AN ACTIVE PRINCIPLE RESERVOIR TO AN INJECTION NOZZLE IN A DEVICE FOR INJECTING SAID ACTIVE PRINCIPLE
EP3572106A1 (en) 2003-04-23 2019-11-27 Valeritas, Inc. Hydraulically actuated pump for long duration medicament administration
US20050209554A1 (en) 2004-03-19 2005-09-22 Sergio Landau Needle-free single-use cartridge and injection system
US7717874B2 (en) 2004-05-28 2010-05-18 Bioject, Inc. Needle-free injection system

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6223786B1 (en) * 1998-11-14 2001-05-01 Pen Jet Corporation Apparatus and method for mixing medication and filling an ampule of a needle-less injector
US6682504B2 (en) * 2000-03-23 2004-01-27 Antares Pharma, Inc. Single use disposable jet injector
US20030187386A1 (en) * 2000-04-07 2003-10-02 Parsons J. Stuart Low cost disposable needleless injector system for variable and fixed dose applications
US20030097093A1 (en) * 2000-05-30 2003-05-22 Alain Navelier Needleless syringe with membrane isolating a multiple duct injector
US20050192530A1 (en) * 2001-04-13 2005-09-01 Penjet Corporation Method and apparatus for needle-less injection with a degassed fluid
US6607510B2 (en) * 2001-11-09 2003-08-19 Bioject Medical Technologies Inc. Disposable needle-free injection apparatus and method
US20060089594A1 (en) * 2004-10-26 2006-04-27 Sergio Landau Needle-free injection device

Also Published As

Publication number Publication date
US20080208114A1 (en) 2008-08-28
US7744563B2 (en) 2010-06-29
WO2008103997A2 (en) 2008-08-28

Similar Documents

Publication Publication Date Title
WO2008103997A3 (en) Needle-free injection devices and drug delivery systems therefor
WO2011014704A3 (en) Infusion pump system with disposable cartridge having pressure venting and pressure feedback
HK1149516A1 (en) Needle-free injection device with nozzle auto-disable
MX2010012691A (en) Autoinjector system.
IL175460A0 (en) Drug delivery device
MX2009013562A (en) Syringe infusion pump.
WO2008140737A3 (en) Drug delivery system with a small amount of a therapeutic agent
WO2009045779A3 (en) Disposable infusion device with reuse lock-out
MX2012014180A (en) Drug delivery device.
WO2007077255A3 (en) A medication delivery device applying a collapsible reservoir
WO2013079652A3 (en) Drug filled delivery assembly
WO2012138177A3 (en) Filter needle
WO2011068647A3 (en) Advanced step therapy delivery for an ambulatory infusion pump and system
WO2009038860A3 (en) Medicament mixing and injection apparatus
WO2014047657A3 (en) Drug pump devices and needle-insertion mechanisms
AU2006310103A8 (en) Modular portable infusion pump
WO2014145548A3 (en) Method and system for controlling delivery of a fluid to and from a patient
WO2010011976A3 (en) Medication delivery devices having penetrable sterility barriers and alignment features
WO2010067319A3 (en) Device for injecting fluid isolated from microneedle hub with dead-space-reducing insert
WO2009140251A3 (en) Medicament delivery device having an electronic circuit system
CA2895719A1 (en) Medical infusion system allowing automatic priming
DE602006010396D1 (en) SPRAY DEVICE WITH A DOSE-LIMITING MECHANISM AND AN ADDITIONAL SAFETY MECHANISM
MX2015000317A (en) Insertion mechanisms having vented fluid pathways for drug delivery pumps.
WO2012112289A3 (en) Manual basal bolus drug delivery device
WO2014053849A3 (en) Injector apparatus

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08730673

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08730673

Country of ref document: EP

Kind code of ref document: A2