WO2008109160A3 - Clay-based hemostatic agents and devices for the delivery thereof - Google Patents

Clay-based hemostatic agents and devices for the delivery thereof Download PDF

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Publication number
WO2008109160A3
WO2008109160A3 PCT/US2008/003082 US2008003082W WO2008109160A3 WO 2008109160 A3 WO2008109160 A3 WO 2008109160A3 US 2008003082 W US2008003082 W US 2008003082W WO 2008109160 A3 WO2008109160 A3 WO 2008109160A3
Authority
WO
WIPO (PCT)
Prior art keywords
substrate
clay
gauze substrate
clay material
delivery
Prior art date
Application number
PCT/US2008/003082
Other languages
French (fr)
Other versions
WO2008109160A2 (en
Inventor
Raymond Huey
Denny Lo
Daniel J. Burns
Original Assignee
Z-Medica Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=39531420&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=WO2008109160(A3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority to CN200880005277.6A priority Critical patent/CN101687056B/en
Priority to JP2009552753A priority patent/JP5327643B2/en
Priority to MX2009009453A priority patent/MX2009009453A/en
Priority to ES08726591T priority patent/ES2394232T3/en
Priority to DK08726591.4T priority patent/DK2142220T3/en
Application filed by Z-Medica Corporation filed Critical Z-Medica Corporation
Priority to EP08726591A priority patent/EP2142220B1/en
Priority to CA2677606A priority patent/CA2677606C/en
Priority to BRPI0808543A priority patent/BRPI0808543B8/en
Priority to PL08726591T priority patent/PL2142220T3/en
Publication of WO2008109160A2 publication Critical patent/WO2008109160A2/en
Publication of WO2008109160A3 publication Critical patent/WO2008109160A3/en
Priority to HK10102794.2A priority patent/HK1136227A1/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/18—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing inorganic materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F13/00—Bandages or dressings; Absorbent pads
    • A61F13/00051—Accessories for dressings
    • A61F13/00063—Accessories for dressings comprising medicaments or additives, e.g. odor control, PH control, debriding, antimicrobic
    • A61F13/01012—
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/22—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing macromolecular materials
    • A61L15/28—Polysaccharides or their derivatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/425—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/44—Medicaments
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/02—Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
    • A61L2300/406—Antibiotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/16—Materials with shape-memory or superelastic properties

Abstract

A hemostatic device for promoting the clotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.
PCT/US2008/003082 2007-03-06 2008-03-06 Clay-based hemostatic agents and devices for the delivery thereof WO2008109160A2 (en)

Priority Applications (10)

Application Number Priority Date Filing Date Title
PL08726591T PL2142220T3 (en) 2007-03-06 2008-03-06 Clay-based hemostatic agents and devices for the delivery thereof
JP2009552753A JP5327643B2 (en) 2007-03-06 2008-03-06 Clay-based hemostatic agent and instrument for its supply
MX2009009453A MX2009009453A (en) 2007-03-06 2008-03-06 Clay-based hemostatic agents and devices for the delivery thereof.
ES08726591T ES2394232T3 (en) 2007-03-06 2008-03-06 Hemostatic agents based on clay and devices for their administration
DK08726591.4T DK2142220T3 (en) 2007-03-06 2008-03-06 Clay-based hemostatic agents and devices for delivery thereof
CN200880005277.6A CN101687056B (en) 2007-03-06 2008-03-06 Hemorrhage based on clay and transfer device thereof
EP08726591A EP2142220B1 (en) 2007-03-06 2008-03-06 Clay-based hemostatic agents and devices for the delivery thereof
CA2677606A CA2677606C (en) 2007-03-06 2008-03-06 Clay-based hemostatic agents and devices for the delivery thereof
BRPI0808543A BRPI0808543B8 (en) 2007-03-06 2008-03-06 Device capable of providing hemostatic effect on bleeding wound
HK10102794.2A HK1136227A1 (en) 2007-03-06 2010-03-16 Clay-based hemostatic agents and devices for the delivery thereof

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US11/715,057 2007-03-06
US11/715,057 US7604819B2 (en) 2006-05-26 2007-03-06 Clay-based hemostatic agents and devices for the delivery thereof

Publications (2)

Publication Number Publication Date
WO2008109160A2 WO2008109160A2 (en) 2008-09-12
WO2008109160A3 true WO2008109160A3 (en) 2009-11-12

Family

ID=39531420

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/003082 WO2008109160A2 (en) 2007-03-06 2008-03-06 Clay-based hemostatic agents and devices for the delivery thereof

Country Status (14)

Country Link
US (11) US7604819B2 (en)
EP (2) EP2508209A1 (en)
JP (2) JP5327643B2 (en)
CN (2) CN106110366B (en)
BR (1) BRPI0808543B8 (en)
CA (1) CA2677606C (en)
DK (1) DK2142220T3 (en)
ES (1) ES2394232T3 (en)
HK (1) HK1136227A1 (en)
MX (1) MX2009009453A (en)
PL (1) PL2142220T3 (en)
PT (1) PT2142220E (en)
RU (1) RU2453339C2 (en)
WO (1) WO2008109160A2 (en)

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US10105259B2 (en) 2000-09-15 2018-10-23 Bruder Healthcare Company, Llc Wound and therapy compress and dressing
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JP2008531498A (en) 2005-02-15 2008-08-14 バージニア コモンウェルス ユニバーシティ Mineral technology (MT) for emergency hemostasis and treatment of acute wounds and chronic ulcers
US8938898B2 (en) 2006-04-27 2015-01-27 Z-Medica, Llc Devices for the identification of medical products
US7968114B2 (en) 2006-05-26 2011-06-28 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
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US7604819B2 (en) 2006-05-26 2009-10-20 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
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