WO2008157536A3 - Hemostatic sponge and method of making the same - Google Patents

Hemostatic sponge and method of making the same Download PDF

Info

Publication number
WO2008157536A3
WO2008157536A3 PCT/US2008/067203 US2008067203W WO2008157536A3 WO 2008157536 A3 WO2008157536 A3 WO 2008157536A3 US 2008067203 W US2008067203 W US 2008067203W WO 2008157536 A3 WO2008157536 A3 WO 2008157536A3
Authority
WO
WIPO (PCT)
Prior art keywords
fibers
hemostatic agent
web
hemostatic
polymer
Prior art date
Application number
PCT/US2008/067203
Other languages
French (fr)
Other versions
WO2008157536A2 (en
Inventor
Denny Lo
Original Assignee
Z-Medica Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Z-Medica Corporation filed Critical Z-Medica Corporation
Publication of WO2008157536A2 publication Critical patent/WO2008157536A2/en
Publication of WO2008157536A3 publication Critical patent/WO2008157536A3/en

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
    • A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
    • A61L15/42—Use of materials characterised by their function or physical properties
    • A61L15/425—Porous materials, e.g. foams or sponges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2400/00—Materials characterised by their function or physical properties
    • A61L2400/04—Materials for stopping bleeding

Abstract

A device for promoting the clotting of blood includes a web of non-woven fibers of a polymer having a hemostatic agent disposed on the fibers. The fibers are randomly arranged to form the web. When the device is applied to a bleeding wound, at least a portion of the hemostatic agent comes into contact with blood to cause the blood to clot. A hemostatic sponge includes a melt-blown non-woven fibrous web of polymer material and a hemostatic agent that is attached to the fibers. A method of making a hemostatic sponge includes the steps of melting a polymer and combining the polymer with a hot air stream. A hemostatic agent is added to the melt. The melt with the hemostatic agent is then drawn into fibers and collected as a web.
PCT/US2008/067203 2007-06-21 2008-06-17 Hemostatic sponge and method of making the same WO2008157536A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US93676807P 2007-06-21 2007-06-21
US60/936,768 2007-06-21

Publications (2)

Publication Number Publication Date
WO2008157536A2 WO2008157536A2 (en) 2008-12-24
WO2008157536A3 true WO2008157536A3 (en) 2009-11-12

Family

ID=39645407

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2008/067203 WO2008157536A2 (en) 2007-06-21 2008-06-17 Hemostatic sponge and method of making the same

Country Status (2)

Country Link
US (1) US20080317831A1 (en)
WO (1) WO2008157536A2 (en)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8858969B2 (en) 2010-09-22 2014-10-14 Z-Medica, Llc Hemostatic compositions, devices, and methods
US8938898B2 (en) 2006-04-27 2015-01-27 Z-Medica, Llc Devices for the identification of medical products

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1667623B1 (en) 2003-09-12 2010-11-24 Z-Medica Corporation Partially hydrated hemostatic agent
US20060178609A1 (en) 2005-02-09 2006-08-10 Z-Medica, Llc Devices and methods for the delivery of molecular sieve materials for the formation of blood clots
US9326995B2 (en) 2005-04-04 2016-05-03 The Regents Of The University Of California Oxides for wound healing and body repair
US8202532B2 (en) 2006-05-26 2012-06-19 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
US7604819B2 (en) 2006-05-26 2009-10-20 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
US7968114B2 (en) 2006-05-26 2011-06-28 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
US20080254147A1 (en) * 2007-04-13 2008-10-16 Z-Medica Corporation Method of providing hemostasis in anti-coagulated blood
CN101508801B (en) * 2009-03-19 2012-09-05 兰州大学 Method for preparing oil-filled styrene butadiene rubber SBR1712/attapulgite stone nano-composite material
US20110015565A1 (en) 2009-07-15 2011-01-20 Hursey Francis X Gas dispenser with therapeutic agent
CN102205143A (en) * 2011-05-25 2011-10-05 吉林大学 Spongy molecular sieve chitosan compound rapid hemostatic material as well as preparation method and application thereof
WO2013048787A1 (en) 2011-09-26 2013-04-04 Yes, Inc. Novel hemostatic compositions and dressings for bleeding
WO2013052577A1 (en) * 2011-10-04 2013-04-11 Z-Medica, Llc Hemostatic fibrous material
CN104507507A (en) 2012-06-22 2015-04-08 Z-医疗有限责任公司 Hemostatic devices
US11931227B2 (en) 2013-03-15 2024-03-19 Cook Medical Technologies Llc Bimodal treatment methods and compositions for gastrointestinal lesions with active bleeding

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2151272A (en) * 1981-11-24 1985-07-17 Kimberly Clark Ltd Absorbent microfibre web
EP1378255A2 (en) * 2002-06-28 2004-01-07 Ethicon, Inc. Hemostatic wound dressing and method of making same
US20050137512A1 (en) * 2003-12-23 2005-06-23 Campbell Todd D. Wound dressing and method for controlling severe, life-threatening bleeding
WO2006088912A2 (en) * 2005-02-15 2006-08-24 Virginia Commonwealth University Mineral technologies (mt) for acute hemostasis and for the treatment of acute wounds and chronic ulcers

Family Cites Families (85)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2969145A (en) * 1956-05-07 1961-01-24 Johnson & Johnson Packaged adhesive bandage
US3189227A (en) * 1962-12-07 1965-06-15 American Home Prod Fluid dispenser
US3386802A (en) * 1967-07-28 1968-06-04 Universal Oil Prod Co Method for preparing spherically-shaped crystalline zeolite particles
JPS5792574A (en) * 1980-11-28 1982-06-09 Nippon Denso Co Manufacture of cordierite ceramics
US4379143A (en) * 1980-12-05 1983-04-05 Pq Corporation Topical liquid or ointment
US4460642A (en) * 1981-06-26 1984-07-17 Minnesota Mining And Manufacturing Company Water-swellable composite sheet of microfibers of PTFE and hydrophilic absorptive particles
JPS58206751A (en) * 1982-05-26 1983-12-02 日石三菱株式会社 Wound covering material
JPS5962050A (en) * 1982-09-30 1984-04-09 日本バイリ−ン株式会社 Skin adhering agent
US4828832A (en) * 1983-09-07 1989-05-09 Laboratorios Biochemie De Mexico Method of manufacturing a composition for treating skin lesions
US4717735A (en) * 1986-04-10 1988-01-05 European Body Wrap, Inc. Composition for body wrap
US5599578A (en) * 1986-04-30 1997-02-04 Butland; Charles L. Technique for labeling an object for its identification and/or verification
US4728323A (en) * 1986-07-24 1988-03-01 Minnesota Mining And Manufacturing Company Antimicrobial wound dressings
US4828081A (en) * 1988-03-04 1989-05-09 Samsonite Corporation Luggage identification system
US5140949A (en) * 1989-09-19 1992-08-25 Mobil Oil Corporation Zeolite-clay composition and uses thereof
US5146932A (en) * 1990-11-01 1992-09-15 Mccabe Francis J Elastic counterpressure garment
DE4322956C2 (en) * 1993-07-09 1995-12-21 Haack Karl Werner An Chitosan film for wound sealing
US5502042A (en) * 1994-07-22 1996-03-26 United States Surgical Corporation Methods and compositions for treating wounds
CA2205934C (en) * 1994-11-28 2002-10-08 John D. Langley A breathable non-woven composite fabric
US5538500A (en) * 1995-02-08 1996-07-23 Peterson; Donald A. Postoperative wound dressing
FR2732585B1 (en) * 1995-04-10 1997-10-17 Garconnet Michel COMPACT LOST PACKAGE FOR FIRST AID DRESSING
US5578022A (en) * 1995-04-12 1996-11-26 Scherson; Daniel A. Oxygen producing bandage and method
US5788682A (en) * 1995-04-28 1998-08-04 Maget; Henri J.R. Apparatus and method for controlling oxygen concentration in the vicinity of a wound
GB9510226D0 (en) * 1995-05-20 1995-07-19 Smith & Nephew Sterilisable cream or paste product for topical application
AUPN851996A0 (en) * 1996-03-07 1996-03-28 John Patrick Gray Improvements in wound care management
JP3311650B2 (en) * 1997-08-19 2002-08-05 日本碍子株式会社 Method for manufacturing cordierite-based ceramic honeycomb structure
US6054379A (en) * 1998-02-11 2000-04-25 Applied Materials, Inc. Method of depositing a low k dielectric with organo silane
US7018392B2 (en) * 1998-04-08 2006-03-28 Arthrocare Corporation Hemostatic system for body cavities
US6086970A (en) * 1998-04-28 2000-07-11 Scimed Life Systems, Inc. Lubricious surface extruded tubular members for medical devices
US6203512B1 (en) * 1999-06-28 2001-03-20 The Procter & Gamble Company Method for opening a packaging device and retrieving an interlabial absorbent article placed therein
JP3423261B2 (en) * 1999-09-29 2003-07-07 三洋電機株式会社 Display device
US6450537B2 (en) * 2000-01-24 2002-09-17 Polaroid Corporation Self-service postage stamp assemblage
AU2001270138A1 (en) * 2000-06-29 2002-01-14 The Night Fun Co. Illuminated emergency signaling device and flying balloon
GB2364989A (en) * 2000-07-14 2002-02-13 Safer Sleep Ltd Labelling of containers for pharmaceuticals
US6622856B2 (en) * 2001-04-25 2003-09-23 Johnson & Johnson Consumer Companies, Inc. Relief kit
PT1397167E (en) * 2001-05-09 2010-05-31 Biointeractions Ltd Wound closure system and methods
US20050147656A1 (en) * 2001-06-14 2005-07-07 Hemcon, Inc. Tissue dressing assemblies, systems, and methods formed from hydrophilic polymer sponge structures such as chitosan
US20050119112A1 (en) * 2002-01-22 2005-06-02 Zeochem, Llc Process for production of molecular sieve adsorbent blends
US20030175333A1 (en) * 2002-03-06 2003-09-18 Adi Shefer Invisible patch for the controlled delivery of cosmetic, dermatological, and pharmaceutical active ingredients onto the skin
US20060193905A1 (en) * 2002-05-14 2006-08-31 University Of Louisville Research Foundation, Inc. Direct cellular energy delivery system
US8269058B2 (en) * 2002-06-14 2012-09-18 Hemcon Medical Technologies, Inc. Absorbable tissue dressing assemblies, systems, and methods formed from hydrophilic polymer sponge structures such as chitosan
US20040101546A1 (en) * 2002-11-26 2004-05-27 Gorman Anne Jessica Hemostatic wound dressing containing aldehyde-modified polysaccharide and hemostatic agents
US6890177B2 (en) * 2002-12-02 2005-05-10 Centrix, Inc. Method and device for the retraction and hemostasis of tissue during crown and bridge procedures
US6701649B1 (en) * 2002-12-12 2004-03-09 Gunter Brosi Combat identification marker
US7060795B2 (en) * 2002-12-19 2006-06-13 Kimberly-Clark Worldwide, Inc. Wound care compositions
AR042493A1 (en) * 2002-12-20 2005-06-22 Procter & Gamble FIBROSA FABRIC, CLEANING TOWEL, DISPOSABLE ABSORBENT ITEM AND ABSORBENT NUCLEUS
US7994078B2 (en) * 2002-12-23 2011-08-09 Kimberly-Clark Worldwide, Inc. High strength nonwoven web from a biodegradable aliphatic polyester
KR100544123B1 (en) * 2003-07-29 2006-01-23 삼성에스디아이 주식회사 Flat panel display
ATE502580T1 (en) * 2003-08-14 2011-04-15 Univ Loma Linda Med DEVICE FOR CLOSING VESSEL WOUNDS
EP1667623B1 (en) * 2003-09-12 2010-11-24 Z-Medica Corporation Partially hydrated hemostatic agent
MX2007000918A (en) * 2004-07-22 2007-12-04 Hemo Nanoscience Llc Compositions and methods for treating excessive bleeding.
US20060121101A1 (en) * 2004-12-08 2006-06-08 Ladizinsky Daniel A Method for oxygen treatment of intact skin
US20060141060A1 (en) * 2004-12-27 2006-06-29 Z-Medica, Llc Molecular sieve materials having increased particle size for the formation of blood clots
US20060178609A1 (en) * 2005-02-09 2006-08-10 Z-Medica, Llc Devices and methods for the delivery of molecular sieve materials for the formation of blood clots
GB0504445D0 (en) * 2005-03-03 2005-04-06 Univ Cambridge Tech Oxygen generation apparatus and method
US20060211965A1 (en) * 2005-03-16 2006-09-21 Z-Medica, Llc Device for the delivery of blood clotting materials to a wound site
CA2602613A1 (en) * 2005-04-04 2006-10-19 The Regents Of The University Of California Inorganic materials for hemostatic modulation and therapeutic wound healing
US9326995B2 (en) * 2005-04-04 2016-05-03 The Regents Of The University Of California Oxides for wound healing and body repair
US7438705B2 (en) * 2005-07-14 2008-10-21 Boehringer Technologies, L.P. System for treating a wound with suction and method detecting loss of suction
EP1937217A2 (en) * 2005-09-13 2008-07-02 Elan Pharma International Limited Nanoparticulate tadalafil formulations
US20070104768A1 (en) * 2005-11-07 2007-05-10 Z-Medica Corporation Devices for the delivery of molecular sieve materials for the formation of blood clots
US20090076475A1 (en) * 2005-11-09 2009-03-19 Oxysure Systems Inc. Method and apparatus for delivering therapeutic oxygen treatments
US8277837B2 (en) * 2006-01-11 2012-10-02 Entegrion, Inc. Hemostatic textile
US20070167971A1 (en) * 2006-01-17 2007-07-19 Raymond Huey Devices and methods for promoting the formation of blood clots in esophageal varices
US7968114B2 (en) * 2006-05-26 2011-06-28 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
US8202532B2 (en) * 2006-05-26 2012-06-19 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
US7604819B2 (en) * 2006-05-26 2009-10-20 Z-Medica Corporation Clay-based hemostatic agents and devices for the delivery thereof
US20080027365A1 (en) * 2006-06-01 2008-01-31 Huey Raymond J Hemostatic device with oxidized cellulose pad
US20080085300A1 (en) * 2006-10-06 2008-04-10 Z-Medica Corporation Hemostatic compositions and method of manufacture
US20080097271A1 (en) * 2006-10-20 2008-04-24 Z-Medica Corporation Devices and methods for the delivery of hemostatic agents to bleeding wounds
US20080125686A1 (en) * 2006-11-29 2008-05-29 Denny Lo Heat mitigating hemostatic agent
US20100184348A1 (en) * 2006-12-20 2010-07-22 Imerys Pigments, Inc. Spunlaid Fibers Comprising Coated Calcium Carbonate, Processes For Their Production, and Nonwoven Products
US20080206134A1 (en) * 2007-02-22 2008-08-28 Denny Lo Radio-opaque hemostatic agents and devices and methods for the delivery thereof
CA2695728A1 (en) * 2007-08-06 2009-02-12 Ohio Medical Corporation Wound treatment system and suction regulator for use therewith
US20090047366A1 (en) * 2007-08-15 2009-02-19 Bedard Robert L Inorganic Coagulation Accelerators for Individuals taking Platelet Blockers or Anticoagulants
US20090053288A1 (en) * 2007-08-20 2009-02-26 Eskridge Jr E Stan Hemostatic woven fabric
US20090162406A1 (en) * 2007-09-05 2009-06-25 Z-Medica Corporation Wound healing with zeolite-based hemostatic devices
US8287506B2 (en) * 2007-10-26 2012-10-16 Electrochemical Oxygen Concepts, Inc. Apparatus and methods for controlling tissue oxygenation for wound healing and promoting tissue viability
US8883194B2 (en) * 2007-11-09 2014-11-11 Honeywell International, Inc. Adsorbent-containing hemostatic devices
US8319002B2 (en) * 2007-12-06 2012-11-27 Nanosys, Inc. Nanostructure-enhanced platelet binding and hemostatic structures
US20100035045A1 (en) * 2008-01-21 2010-02-11 Imerys Pigments, Inc. Fibers comprising at least one filler and processes for their production
US20110059287A1 (en) * 2008-01-21 2011-03-10 Imerys Pigments, Inc. Fibers comprising at least one filler, processes for their production, and uses thereof
EP2276879B1 (en) * 2008-04-11 2015-11-25 Virginia Commonwealth University Electrospun dextran fibers and devices formed therefrom
US20110015565A1 (en) * 2009-07-15 2011-01-20 Hursey Francis X Gas dispenser with therapeutic agent
US20120004636A1 (en) * 2010-07-02 2012-01-05 Denny Lo Hemostatic fibrous material
US8858969B2 (en) * 2010-09-22 2014-10-14 Z-Medica, Llc Hemostatic compositions, devices, and methods

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2151272A (en) * 1981-11-24 1985-07-17 Kimberly Clark Ltd Absorbent microfibre web
EP1378255A2 (en) * 2002-06-28 2004-01-07 Ethicon, Inc. Hemostatic wound dressing and method of making same
US20050137512A1 (en) * 2003-12-23 2005-06-23 Campbell Todd D. Wound dressing and method for controlling severe, life-threatening bleeding
WO2006088912A2 (en) * 2005-02-15 2006-08-24 Virginia Commonwealth University Mineral technologies (mt) for acute hemostasis and for the treatment of acute wounds and chronic ulcers

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8938898B2 (en) 2006-04-27 2015-01-27 Z-Medica, Llc Devices for the identification of medical products
US8858969B2 (en) 2010-09-22 2014-10-14 Z-Medica, Llc Hemostatic compositions, devices, and methods

Also Published As

Publication number Publication date
US20080317831A1 (en) 2008-12-25
WO2008157536A2 (en) 2008-12-24

Similar Documents

Publication Publication Date Title
WO2008157536A3 (en) Hemostatic sponge and method of making the same
US10213343B2 (en) Three-layered wound dressing and method of manufacturing the same
JP2005514232A5 (en)
AU2012201128B2 (en) Adhesive bandage
WO2012051373A3 (en) Antimicrobial substrate
WO2010009043A3 (en) Multi-component filter media with nanofiber attachment
US8063264B2 (en) Hemostatic media
JP2008526281A5 (en)
BR0311135A (en) Non-woven fibrous veil, and method of preparing the same
EP2513365A4 (en) Dimensionally stable nonwoven fibrous webs, melt blown fine fibers, and methods of making and using the same
WO2007081996A3 (en) Hemostatic textile
WO2007027990A3 (en) Elastomeric fibers comprising controlled distribution block copolymers
WO2007092303A3 (en) Absorbent non-woven fibrous mats and process for preparing same
WO2007112443A3 (en) Micro and nanofiber nonwoven spunbonded fabric
WO2008008266A3 (en) Biohybrid elastomeric scaffolds and methods of use thereof
WO2008150970A3 (en) High-output solvent-based electrospinning
CN101172072A (en) Pressure-sensitive adhesive tape or sheet for medical treatment
WO2008149248A3 (en) Methods of applying skin wellness agents to a nonwoven web through electrospinning nanofibers
DE502006002984D1 (en) Elastic composite nonwoven fabric and process for its production
MX2012004171A (en) Honeycomb sandwich construction for the automotive industry.
WO2011084326A3 (en) Hemostatic agents and wound dressings
CN104780950A (en) Odor control material prepared by extrusion comprising particles encapsulated in a polymeric matrix
ATE507965T1 (en) MULTI-LAYER COMPOSITE NON-WOVEN FABRIC, FLUID FILTER AND METHOD FOR PRODUCING THE NON-WOVEN FABRIC
WO2008010947A3 (en) Device for treating wound gaps
WO2010040071A3 (en) Wipe materials comprising regenerated plant-protein fibres

Legal Events

Date Code Title Description
121 Ep: the epo has been informed by wipo that ep was designated in this application

Ref document number: 08771257

Country of ref document: EP

Kind code of ref document: A2

NENP Non-entry into the national phase

Ref country code: DE

122 Ep: pct application non-entry in european phase

Ref document number: 08771257

Country of ref document: EP

Kind code of ref document: A2