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Publication numberWO2012089722 A2
Publication typeApplication
Application numberPCT/EP2011/074073
Publication dateJul 5, 2012
Filing dateDec 27, 2011
Priority dateDec 30, 2010
Also published asCN103476254A, CN103491776A, EP2471363A1, EP2658375A2, EP2658376A1, US20140011682, US20140038822, WO2012089721A1, WO2012089722A3
Publication numberPCT/2011/74073, PCT/EP/11/074073, PCT/EP/11/74073, PCT/EP/2011/074073, PCT/EP/2011/74073, PCT/EP11/074073, PCT/EP11/74073, PCT/EP11074073, PCT/EP1174073, PCT/EP2011/074073, PCT/EP2011/74073, PCT/EP2011074073, PCT/EP201174073, WO 2012/089722 A2, WO 2012089722 A2, WO 2012089722A2, WO-A2-2012089722, WO2012/089722A2, WO2012089722 A2, WO2012089722A2
InventorsJens Frackenpohl, Isolde HÄUSER-HAHN, Ines Heinemann, Martin Jeffrey Hills, Stefan Lehr, Thomas Müller, Christpher Hugh ROSINGER, KOSKULL-DÖRING Pascal VON, Lothar Willms
ApplicantBayer Cropscience Ag
Export CitationBiBTeX, EndNote, RefMan
External Links: Patentscope, Espacenet
Use of open-chain carboxylic acids, carbonic esters, carboxamides and carbonitriles of aryl, heteroaryl and benzylsulfonamide or the salts thereof for improving the stress tolerance in plants
WO 2012089722 A2
Abstract
The invention relates to the use of open-chain carboxylic acids, carbonic esters, carboxamides and carbonitriles of aryl, heteroaryl and benzylsulfonamide or the salts thereof of general formula (I), wherein the respective substituents are defined as in the description, for improving the stress tolerance of plant sto abiotic stress, and for promoting plant growth and/or for increasing plant yield.
Claims(1)  translated from German
  1. Patentansprüche Claims
    Verwendung von offenkettigen Aryl-, Heteroaryl- und Use of open-chain aryl, heteroaryl and
    Benzylsulfonamidocarbonsäuren, -carbonsäureestern, -carbonsäureamiden und -carbonitrilen der allgemeinen Formel (I) oder deren Salze Benzylsulfonamidocarbonsäuren carboxylic acid esters, and -carbonitrilen -carboxamides of the general formula (I) or salts thereof
    Figure imgf000289_0001
    zur Toleranzerhöhung gegenüber abiotischem Stress in Pflanzen, worin Q für die Gruppierungen to increase tolerance to abiotic stress in plants, where Q represents the groups
    Figure imgf000289_0002
    Q-22 Q-23 Q-24 steht, und wobei die Reste R 4 bis R 8 , und R 41 bis R 84 sowie Y und m und p jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zum Schwefelatom der S0 2 -Gruppe steht; Q-22 Q-23 Q-24 is, and where the radicals R 4 to R 8 and R 41 to R 84 and Y and m and p are each as defined in accordance with the following definitions and where the arrow represents a bond to the sulfur atom the S0 2 group;
    A 1 , A 2 , A 3 gleich oder verschieden sind und unabhängig voneinander für N (Stickstoff) oder die Gruppierung CW stehen, wobei jedoch in keinem Fall mehr als zwei N-Atome benachbart sind, und wobei W in der Gruppierung CW jeweils gleiche oder verschiedene Bedeutungen gemäß der nachstehenden Definition hat, jeweils für Wasserstoff, Nitro, Amino, Cyano, Thiocyanato, A 1, A 2, A 3 are identical or different and are each independently N (nitrogen) or the grouping are CW, but in no case more than two N atoms are adjacent, and wherein W in the group, the same or CW different meanings as defined below, has in each case represent hydrogen, nitro, amino, cyano, thiocyanato,
    Isothiocyanato, Halogen, (Ci-C 8 )-Alkyl, (C 3 -C 8 )-Cycloalkyl, (C 2 -C 8 )- Alkenyl, (C 2 -C 8 )-Alkinyl, Aryl, Aryl-(Ci-C 8 )-alkyl, Aryl-(Ci-C 6 )-alkoxy, Heteroaryl, (Ci-C 6 )-Alkoxy-(Ci-C 8 )-alkyl, (Ci-Cs)-Haloalkyl, (C 3 -C 8 )- Halocycloalkyl, (Ci-Cs)-Alkoxy, (Ci-Cs)-Haloalkoxy, Aryloxy, Isothiocyanato, halogen, (Ci-C 8) alkyl, (C 3 -C 8) -cycloalkyl, (C 2 -C 8) - alkenyl, (C 2 -C 8) -alkynyl, aryl, aryl- (Ci- C 8) alkyl, aryl (Ci-C 6) alkoxy, heteroaryl, (Ci-C 6) alkoxy (Ci-C 8) alkyl, (Ci-Cs) -haloalkyl, (C 3 -C 8) - halocycloalkyl, (Ci-Cs) alkoxy, (Ci-Cs) haloalkoxy, aryloxy,
    Heteroaryloxy, (C3-C 8 )-Cycloalkyloxy, (C3-C 8 )-Cycloalkyl-(Ci-C 8 )- alkoxy, (Ci-Cs)-Alkoxycarbonyl, (Ci-C6)-Alkoxycarbonyl-(Ci-C6)-alkyl, Hydroxycarbonyl, Aminocarbonyl, (Ci-Cs)-Alkylaminocarbonyl, (C3-C 8 )- Cycloalkylaminocarbonyl, Cyano-(Ci-C 8 )-alkylaminocarbonyl, (C 2 -C 8 )- Alkenylaminocarbonyl, (C2-C 8 )-Alkinylaminocarbonyl, (Ci-C 8 )- Alkylamino, (Ci-Cs)-Alkylthio, (Ci-Cs)-Haloalkylthio, Bis-(Ci-Cs)- alkylamino, (C3-C 8 )-Cycloalkylamino, (Ci-Cs)-Alkylcarbonylamino, (C3-C 8 )-Cycloalkylcarbonylamino, Formylamino, (Ci-C 8 )- Haloalkylcarbonylamino, (Ci-Cs)-Alkoxycarbonylamino, (Ci-C 8 )- Alkylaminocarbonylamino, Bis-[(Ci-C 8 )-Alkyl]-aminocarbonyl-amino, (Ci-C 8 )-Alkylsulfonylamino, (C3-C 8 )-Cycloalkylsulfonylamino, Heteroaryloxy, (C3-C8) cycloalkyloxy, (C3-C8) cycloalkyl- (Ci-C 8) - alkoxy, (Ci-Cs) -alkoxycarbonyl, (Ci-C6) -alkoxycarbonyl (Ci-C6) alkyl, hydroxycarbonyl, aminocarbonyl, (Ci-Cs) -alkylaminocarbonyl, (C3-C8) - cycloalkylaminocarbonyl, cyano (Ci-C 8) alkylaminocarbonyl, (C 2 -C 8) - alkenylaminocarbonyl, (C2-C8 ) -Alkinylaminocarbonyl, (Ci-C 8) - alkyl amino, (Ci-Cs) -alkylthio, (Ci-Cs) haloalkylthio, bis (Ci-Cs) - alkylamino, (C3-C8) cycloalkylamino, (Ci -CS) alkylcarbonylamino, (C3-C8) -Cycloalkylcarbonylamino, formylamino, (Ci-C 8) - Haloalkylcarbonylamino, (Ci-Cs) alkoxycarbonylamino, (Ci-C 8) - alkylaminocarbonylamino, bis - [(C 8) -alkyl] aminocarbonyl-amino, (Ci-C8) alkylsulfonylamino, (C3-C8) -Cycloalkylsulfonylamino,
    Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl-(Ci-Cs)- haloalkylamino, Amino-(Ci-C 8 )-alkylsulfonyl, Amino-(Ci-C 8 )- haloalkylsulfonyl, (Ci-Cs)-Alkylsulfonyl, (C3-C 8 )-Cycloalkylsulfonyl, Arylsulfonyl, (Ci-Cs)-Alkylsulfinyl, (C 3 -C 8 )-Cycloalkylsulfinyl, Arylsulfinyl, N,S-Di-(Ci-C 8 )-alkylsulfonimidoyl, S-(Ci-C 8 )-Alkylsulfonimidoyl, Arylsulfonylamino, Hetarylsulfonylamino, sulfonyl (Ci-Cs) - haloalkylamino, amino (Ci-C 8) alkylsulfonyl, amino (Ci-C 8) - haloalkylsulfonyl, (Ci-Cs) alkylsulfonyl, (C3-C8) cycloalkylsulfonyl, arylsulfonyl, (Ci-Cs) alkylsulfinyl, (C 3 -C 8) -Cycloalkylsulfinyl, arylsulfinyl, N, S-di- (Ci-C 8) -alkylsulfonimidoyl, S- (Ci-C 8) -Alkylsulfonimidoyl .
    (Ci-C 8 )-Alkylsulfonylaminocarbonyl, (C3-C 8 )- Cycloalkylsulfonylaminocarbonyl, (C3-C 8 )-Cycloalkylaminosulfonyl, Aryl-(Ci-C 8 )-alkylcarbonylamino, (C 3 -C 8 )-Cycloalkyl-(Ci-C 8 )- alkylcarbonylamino, Heteroarylcarbonylamino, (Ci-C 8 )-Alkoxy-(Ci-C 8 )- alkylcarbonylamino, Hydroxy-(Ci-C 8 )-alkylcarbonylamino steht, für H, Nitro, Amino, Cyano, Halogen, (Ci-Cs)-Alkyl, (C 3 -C 8 )-Cycloalkyl, (C 2 -C 8 )-Alkenyl, (C 2 -C 8 )-Alkinyl, Aryl, Aryl-(Ci-C 8 )-alkyl, Heteroaryl, (Ci-Ce)-Alkoxy-(Ci-Ce)-alkyl, (Ci-C 8 )-Haloalkyl, (C 3 -C 8 )-Halocycloalkyl, (Ci-Ce)-Alkoxy, (Ci-C 8 )-Haloalkoxy, (Ci-Ce)-Alkylthio, (Ci-C 8 )- Haloalkylthio, (Ci-Cs)-Alkoxycarbonyl, Hydroxycarbonyl, (Ci-C 8) -Alkylsulfonylaminocarbonyl, (C3-C8) - Cycloalkylsulfonylaminocarbonyl, (C3-C 8) -Cycloalkylaminosulfonyl, aryl (Ci-C8) alkylcarbonylamino, (C 3 -C 8) cycloalkyl (C -C 8) - alkylcarbonylamino, heteroarylcarbonylamino, (Ci-C 8) alkoxy (Ci-C 8) - alkylcarbonylamino, hydroxy (Ci-C8) alkylcarbonylamino, represents H, nitro, amino, cyano, halogen, (Ci-Cs) alkyl, (C 3 -C 8) -cycloalkyl, (C 2 -C 8) -alkenyl, (C 2 -C 8) alkynyl, aryl, aryl (Ci-C 8) alkyl , heteroaryl, (Ci-Ce) alkoxy- (Ci-Ce) alkyl, (Ci-C8) -haloalkyl, (C 3 -C 8) halocycloalkyl, (Ci-Ce) alkoxy, (Ci-C 8) haloalkoxy, (Ci-Ce) -alkylthio, (C 8) - haloalkylthio, (Ci-Cs) alkoxycarbonyl, hydroxycarbonyl,
    Aminocarbonyl, (Ci-C 8 )-Alkylaminocarbonyl, (Ci-Cs)-Alkylamino, Bis- (Ci-C 8 )-alkylamino, (C3-C 8 )-Cycloalkylamino, (Ci-C 8 )- Alkylcarbonylamino, (C3-C 8 )-Cycloalkylcarbonylamino, Formylamino, (Ci-C 8 )-Haloalkylcarbonylamino, (Ci-C 8 )-Alkoxycarbonylamino, Aminocarbonyl, (Ci-C8) alkylaminocarbonyl, (Ci-Cs) alkyl amino, bis (C 8) alkylamino, (C3-C8) cycloalkylamino, (Ci-C 8) - alkylcarbonylamino, (C3 C8) -Cycloalkylcarbonylamino, formylamino, (Ci-C 8) -Haloalkylcarbonylamino, (Ci-C 8) alkoxycarbonylamino,
    [(Ci-C 8 )-Alkyl-]aminocarbonyl-amino, Sulfonylamino, (Ci-C 8 )- Alkylsulfonylamino, (Ci-C 8 )-Haloalkylsulfonylamino, (C3-C 8 )- Cycloalkylsulfonylamino, Amino-(Ci-C 8 )-alkylsulfonyl, Amino-(Ci-C 8 )- haloalkylsulfonyl, (Ci-Cs)-Alkylsulfonyl, (C3-C 8 )-Cycloalkylsulfonyl, Arylsulfonyl, (Ci-Cs)-Alkylsulfinyl, (C 3 -C 8 )-Cycloalkylsulfinyl, Arylsulfinyl, N,S-Di-(Ci-C 8 )-alkylsulfonimidoyl, S-(Ci-C 8 )-Alkylsulfonimidoyl, [(Ci-C 8) -alkyl] aminocarbonyl-amino, sulfonylamino, (Ci-C 8) - alkylsulfonylamino, (Ci-C 8) -Haloalkylsulfonylamino, (C3-C8) - cycloalkylsulfonylamino, amino (Ci-C 8) alkylsulfonyl, amino (Ci-C 8) - haloalkylsulfonyl, (Ci-Cs) alkylsulfonyl, (C3-C8) cycloalkylsulfonyl, arylsulfonyl, (Ci-Cs) alkylsulfinyl, (C 3 -C 8) -Cycloalkylsulfinyl, arylsulfinyl, N, S-di- (Ci-C 8) -alkylsulfonimidoyl, S- (Ci-C 8) -Alkylsulfonimidoyl,
    (Ci-C 8 )-Alkylsulfonylaminocarbonyl, (C3-C 8 )- Cycloalkylsulfonylaminocarbonyl, (C3-C 8 )-Cycloalkylaminosulfonyl, Amino-(Ci-C 8 )-alkyl, Amino-(C2-C 8 )-alkenyl, (C2-C 8 )-Alkenylamino, (C2- C 8 )-Alkenylimino steht, für H, Nitro, Amino, Cyano, Halogen, (Ci-Cs)-Alkyl, (C 3 -C 8 )-Cycloalkyl, (C 2 -C 8 )-Alkenyl, (C 2 -C 8 )-Alkinyl, Aryl, Aryl-(Ci-C 8 )-alkyl, Heteroaryl, (Ci-C 8) -Alkylsulfonylaminocarbonyl, (C3-C8) - Cycloalkylsulfonylaminocarbonyl, (C3-C 8) -Cycloalkylaminosulfonyl, amino (Ci-C 8) -alkyl, amino- (C2-C8) alkenyl, ( C2-C8) -alkenylamino, (C 2 C 8) -Alkenylimino, represents H, nitro, amino, cyano, halogen, (Ci-Cs) alkyl, (C 3 -C 8) -cycloalkyl, (C 2 -C 8) -alkenyl, (C 2 -C 8) alkynyl, aryl, aryl (Ci-C 8) alkyl, heteroaryl,
    (Ci-C 8 )-Alkoxy-(Ci-C 8 )-alkyl, (Ci-Cs)-Haloalkyl, (C 3 -C 8 )-Halocycloalkyl, (Ci-Cs)-Alkoxy, (Ci-C 8 )-Haloalkoxy, (Ci-Cs)-Alkylthio, (Ci-C 8 )- Haloalkylthio, (Ci-Cs)-Alkoxycarbonyl, Hydroxycarbonyl, (Ci-C 8) alkoxy (Ci-C 8) alkyl, (Ci-Cs) -haloalkyl, (C 3 -C 8) halocycloalkyl, (Ci-Cs) alkoxy, (Ci-C 8) haloalkoxy, (Ci-Cs) -alkylthio, (C 8) - haloalkylthio, (Ci-Cs) alkoxycarbonyl, hydroxycarbonyl,
    Aminocarbonyl, (Ci-Cs)-Alkylaminocarbonyl, (Ci-Cs)-Alkylamino, Bis- (Ci-Cs)-alkylamino, (C 3 -C 8 )-Cycloalkylamino, (Ci-C 8 )- Aminocarbonyl, (Ci-Cs) alkylaminocarbonyl, (Ci-Cs) alkylamino, bis (Ci-Cs) alkylamino, (C 3 -C 8) cycloalkylamino, (Ci-C 8) -
    Alkylcarbonylamino, (C3-C 8 )-Cycloalkylcarbonylamino, Formylamino, (Ci-C 8 )-Haloalkylcarbonylamino, (Ci-Cs)-Alkoxycarbonylamino, Alkylcarbonylamino, (C3-C8) -Cycloalkylcarbonylamino, formylamino, (Ci-C 8) -Haloalkylcarbonylamino, (Ci-Cs) alkoxycarbonylamino,
    [(Ci-C 8 )-Alkyl-]-aminocarbonyl-amino, Sulfonylamino, (Ci-C 8 )- Alkylsulfonylamino, (Ci-Cs)-Haloalkylsulfonylamino, (C3-C 8 )- Cycloalkylsulfonylamino, Amino-(Ci-C 8 )-alkylsulfonyl, Amino-(Ci-C 8 )- haloalkylsulfonyl, (Ci-Cs)-Alkylsulfonyl, (C3-C 8 )-Cycloalkylsulfonyl, Arylsulfonyl, (Ci-Cs)-Alkylsulfinyl, (C 3 -C 8 )-Cycloalkylsulfinyl, Arylsulfinyl, N,S-Di-(Ci-C 8 )-alkylsulfonimidoyl, S-(Ci-C 8 )-Alkylsulfonimidoyl, [(Ci-C8) alkyl -] - aminocarbonyl-amino, sulfonylamino, (Ci-C 8) - alkylsulfonylamino, (Ci-Cs) -Haloalkylsulfonylamino, (C3-C8) - cycloalkylsulfonylamino, amino (Ci-C 8) alkylsulfonyl, amino (Ci-C 8) - haloalkylsulfonyl, (Ci-Cs) alkylsulfonyl, (C3-C8) cycloalkylsulfonyl, arylsulfonyl, (Ci-Cs) alkylsulfinyl, (C 3 -C 8) -Cycloalkylsulfinyl, arylsulfinyl, N, S-di- (Ci-C 8) -alkylsulfonimidoyl, S- (Ci-C 8) -Alkylsulfonimidoyl,
    (Ci -C8)-Alkylsulfonylaminocarbonyl, (C3-C8)- Cycloalkylsulfonylaminocarbonyl, (C3-C8)-Cycloalkylaminosulfonyl, Amino-(Ci -C8)-alkyl, Amino-(C2-C8)-alkenyl, (C2-C8)-Alkenylamino, (C2- C8)-Alkenylimino steht, (Ci-C8) -Alkylsulfonylaminocarbonyl, (C3-C8) - Cycloalkylsulfonylaminocarbonyl, (C3-C8) -Cycloalkylaminosulfonyl, amino (Ci-C8) alkyl, amino (C2-C8) alkenyl, (C2-C8) - alkenylamino, (C2- C8) -Alkenylimino stands,
    R 1 und R 2 mit den Atomen, an die sie gebunden sind, einen vollständig R 1 and R 2 with the atoms to which they are attached form a fully
    gesättigten, teilgesättigten oder vollständig ungesättigten, saturated, partially saturated or fully unsaturated,
    gegebenenfalls durch Heteroatome unterbrochenen und optionally interrupted by hetero atoms and
    gegebenenfalls weiter durch W substituierten 5 bis 7-gliedrigen Ring bilden, und wobei sie im Falle der Verbindungen der allgemeinen Formel (I) mit den Gruppierungen Q-21 und Q-23 einen optionally further form to 7-membered ring substituted by W 5, and wherein a in the case of compounds of general formula (I) with the moieties Q-21 and Q-23
    entsprechenden Ring bilden müssen. must make appropriate ring.
    R 1 und A 3 , wenn A 3 für eine Gruppe CW steht, mit den Atomen, an die sie R 1 and A 3, when A 3 is a group CW, with the atoms to which they
    gebunden sind, einen vollständig gesättigten, teilgesättigten oder vollständig ungesättigten, gegebenenfalls durch Heteroatome unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7- gliedrigen Ring bilden, are attached form a fully saturated, partially saturated or fully unsaturated, optionally interrupted by hetero atoms and optionally further substituted 5 to 7-membered ring form,
    X für eine direkte Bindung oder für eine Gruppierung (CHR 3 ) n steht, und wobei R 3 in der Gruppierung (CHR 3 ) n jeweils gleiche oder X is a direct bond or a group (CHR 3) n and wherein R 3 in the group (CHR 3) n, the same or
    verschiedene Bedeutungen gemäß der nachstehenden Definition hat, n für 0, 1 steht, different meanings as defined below, has n is 0, 1;
    R 3 für H, (Ci -Ce)-Alkyl, (C 2 -Ce)-Alkenyl-(Ci -Ce)-alkyl, (Ci-C 8 )-Haloalkyl, R 3 is H, (Ci -Ce) alkyl, (C 2 -Ce) alkenyl (Ci -Ce) alkyl, (Ci-C 8) haloalkyl,
    (C 3 -C 8 )-Cycloalkyl, (C3-C 8 )-Cycloalkyl-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkyl, Heteroaryl-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkoxy-(Ci-C 8 )-alkyl, (Ci-C 8 )- Haloalkoxy-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkylthio-(Ci-C 8 )-alkyl, (Ci-C 8 )- Haloalkylthio-(Ci-C 8 )-alkyl steht, für H, (Ci-Ce)-Alkyl, (C 2 -C8)-Alkenyl-(Ci-C 8 )-alkyl, (C 2 -C 8 )-Alkinyl, (C 3 -C 8) -cycloalkyl, (C3-C8) cycloalkyl (Ci-C 8) alkyl, aryl (Ci-C 8) alkyl, heteroaryl (Ci-C 8) alkyl, (Ci-C 8) alkoxy (Ci-C 8) alkyl, (Ci-C 8) - haloalkoxy (Ci-C 8) alkyl, (Ci-C8) alkylthio (Ci-C 8 ) alkyl, (Ci-C 8) - Haloalkylthio- (Ci-C 8) -alkyl, H, (Ci-Ce) alkyl, (C 2 -C 8) alkenyl (Ci-C 8) - alkyl, (C 2 -C 8) alkynyl,
    (Ci-C8)-Alkylcarbonyl, (C3-C8)-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl, (Ci-C8)-Alkoxycarbonyl, Aryl-(Ci-Cs)- alkoxycarbonyl, (C3-C8)-Cycloalkoxycarbonyl, (C 3 -C 8 )-Cycloalkyl- (Ci-Ce)-alkoxycarbonyl, (Ci-Ce)-Alkylsulfonyl, (C 3 -C 8 )- Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C8)-Alkoxycarbonylcarbonyl, Aryl- (Ci-C8)-alkoxycarbonylcarbonyl, (Ci-C8)-Alkylaminothiocarbonyl, (Ci-C8) alkylcarbonyl, (C3-C8) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl, (Ci-C8) -alkoxycarbonyl, aryl (Ci-Cs) - alkoxycarbonyl, (C3-C8) cycloalkoxycarbonyl, (C 3 - C 8) cycloalkyl- (Ci-Ce) alkoxycarbonyl, (Ci-Ce) alkylsulfonyl, (C 3 -C 8) - cycloalkylsulfonyl, arylsulfonyl, (Ci-C8) -Alkoxycarbonylcarbonyl, aryl (Ci-C8) - alkoxycarbonylcarbonyl, (Ci-C8) -Alkylaminothiocarbonyl,
    (Ci-Ce)-Alkylaminocarbonyl, Aryl-(Ci-C 8 )-alkyl, Hetaroaryl-(Ci-C 8 )-alkyl, Cyano-(Ci-C 8 )-alkyl, (Ci-C 8 )-Haloalkyl, (C 3 -C 8 )-Cycloalkyl, (C 3 -C 8 )- Cycloalkyl-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkoxy-(Ci-C 8 )-alkyl, (Ci-C 8 )- Haloalkoxy-(Ci-C 8 )-alkyl, (C 2 -C8)-Alkinyl-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkoxycarbonyl-(Ci-C8)-alkyl, Aminocarbonyl-(Ci-C8)-alkyl, (Ci-C 8 )- Alkylaminocarbonyl-(Ci-C8)-alkyl, Bis-(Ci-C 8 )-alkylaminocarbonyl- (Ci-C 8 )-alkyl steht, für Halogen, (C2-C 8 )-Alkyl, (Ci-C 8 )-Alkoxy, (Ci-C 8 )-Alkoxycarbonyloxy, (C 2 -C 8 )-Alkenyl, (C 2 -C 8 )-Haloalkenyl, (C 2 -C 8 )-Alkenyl-(Ci-C 8 )-alkyl, (C 2 -C 8 )-Alkinyl, (C 2 -C 8 )-Alkinyl-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkyl, Bisaryl- (Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkoxyaryl-(Ci-C 8 )-alkyl, Aryloxyaryl-(Ci-Cs)- alkyl, (Ci-C 8 )-Alkoxyaryl-(Ci-C 8 )-alkyl, Heteroaryl-(Ci-C 8 )-alkyl, (Ci-Ce) alkylaminocarbonyl, aryl (Ci-C 8) alkyl, Hetaroaryl- (Ci-C 8) -alkyl, cyano- (Ci-C 8) alkyl, (Ci-C 8) haloalkyl, (C 3 -C 8) cycloalkyl, (C 3 -C 8) - cycloalkyl, (Ci-C 8) alkyl, (Ci-C 8) alkoxy (Ci-C 8) alkyl, (Ci- C 8) - haloalkoxy (Ci-C 8) alkyl, (C 2 -C 8) alkynyl (Ci-C 8) alkyl, (Ci-C8) - alkoxycarbonyl (Ci-C8) alkyl, aminocarbonyl (Ci-C8) alkyl, (Ci-C 8) - alkylaminocarbonyl (Ci-C8) alkyl, bis (Ci-C 8) alkylaminocarbonyl (Ci-C8) -alkyl, halogen , (C2-C8) alkyl, (Ci-C 8) alkoxy, (Ci-C8) -alkoxycarbonyloxy, (C 2 -C 8) -alkenyl, (C 2 -C 8) haloalkenyl, (C 2 -C 8) alkenyl (Ci-C 8) alkyl, (C 2 -C 8) -alkynyl, (C 2 -C 8) alkynyl (Ci-C 8) alkyl, aryl (C -C 8) alkyl, bisaryl (Ci-C 8) alkyl, aryl (Ci-C 8) -alkoxyaryl- (Ci-C 8) alkyl, Aryloxyaryl- (Ci-Cs) - alkyl, (Ci -C 8) -Alkoxyaryl- (Ci-C 8) alkyl, heteroaryl (Ci-C 8) alkyl,
    Heterocyclyl-(Ci-C 8 )-alkyl, N-(Ci-C 8 )-Alkylheterocyclyl-(Ci-C 8 )-alkyl, N- [(Ci-C 8 )-Alkoxycarbonyl]heterocyclyl-(Ci-C 8 )-alkyl, N-(Aryl-(Ci-C 8 )- alkoxycarbonyl)heterocyclyl-(Ci-C8)-alkyl, N-(Arylcarbonyl)heterocyclyl- (Ci-C 8 )-alkyl, N-[(Ci-C 8 )-Alkylcarbonyl]heterocyclyl-(Ci-C 8 )-alkyl, N- [(C3-C8)-Cycloalkylcarbonyl]heterocyclyl-(Ci-C8)-alkyl, Cyano-(Ci-Cs)- alkyl, (Ci-C 8 )-Haloalkyl, (C 3 -C 8 )-Cycloalkyl, (C 3 -C 8 )-Halocycloalkyl, (C 4 -C 8 )-Cycloalkenyl, (C 3 -C 8 )-Cycloalkyl-(Ci-C 8 )-alkyl, (C 3 -C 8 )- Cycloalkenyl-(Ci-C 8 )-alkyl, Hydroxy-(Ci-C 8 )-alkyl, (Ci-Cs)-Alkoxy- (Ci-Cs)-alkyl, (Ci-C 8 )-Haloalkoxy-(Ci-C 8 )-alkyl, Aryloxy-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkoxy-(Ci-C 8 )-alkyl, Heteroaryl-(Ci-C 8 )-alkoxy-(Ci-C 8 )- alkyl, (C 3 -C 8 )-Cycloalkoxy-(Ci-C 8 )-alkyl, (C 3 -C 8 )-Cycloalkyl-(Ci-C 8 )- alkoxy-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkylcarbonyloxy-(Ci-C 8 )-alkyl, Arylcarbonyloxy-(Ci-C8)-alkyl, Heteroarylcarbonyloxy-(Ci-C8)-alkyl, (C3-C8)-Cycloalkylcarbonyloxy-(Ci-C8)-alkyl, Arylsulfonyloxy-(Ci-C8)- alkyl, (Ci-C 8 )-Alkylsulfonyloxy-(Ci-C 8 )-alkyl, Hydrothio-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkylthio-(Ci-C 8 )-alkyl, (Ci-C 8 )-Haloalkylthio-(Ci-C 8 )-alkyl, Aryl- (Ci-Cs)-alkylthio-(Ci-C 8 )-alkyl, (C 3 -C8)-Cycloalkylthio-(Ci-C 8 )-alkyl, Arylthio-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkylsulfinyl-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkylsulfonyl-(Ci-C 8 )-alkyl, (Ci-C 8 )-Haloalkylsulfinyl-(Ci-C 8 )-alkyl, Heterocyclyl (Ci-C 8) -alkyl, N- (Ci-C 8) -Alkylheterocyclyl- (Ci-C 8) -alkyl, N [(Ci-C8) alkoxycarbonyl] heterocyclyl (Ci-C 8 ) alkyl, N- (aryl (Ci-C8) - alkoxycarbonyl) heterocyclyl (Ci-C8) alkyl, N- (arylcarbonyl) heterocyclyl- (Ci-C 8) -alkyl, N - [(Ci- C 8) alkylcarbonyl] heterocyclyl (Ci-C 8) -alkyl, N [(C3-C8) cycloalkylcarbonyl] heterocyclyl (Ci-C8) alkyl, cyano (Ci-Cs) - alkyl, (Ci -C 8) haloalkyl, (C 3 -C 8) cycloalkyl, (C 3 -C 8) halocycloalkyl, (C 4 -C 8) cycloalkenyl, (C 3 -C 8) cycloalkyl (Ci- C 8) alkyl, (C 3 -C 8) - cycloalkenyl, (Ci-C 8) alkyl, hydroxy (Ci-C 8) alkyl, (Ci-Cs) alkoxy- (Ci-Cs) - alkyl, (Ci-C 8) haloalkoxy (Ci-C 8) alkyl, aryloxy (Ci-C8) alkyl, aryl (Ci-C 8) alkoxy (Ci-C 8) alkyl , heteroaryl (Ci-C 8) alkoxy (Ci-C 8) - alkyl, (C 3 -C 8) cycloalkoxy (Ci-C 8) alkyl, (C 3 -C 8) cycloalkyl (Ci-C 8) - alkoxy- (Ci-C 8) alkyl, (Ci-C8) alkylcarbonyloxy (Ci-C 8) alkyl, arylcarbonyloxy (Ci-C8) alkyl, Heteroarylcarbonyloxy- (Ci C8) alkyl, (C3-C8) -Cycloalkylcarbonyloxy- (Ci-C8) alkyl, arylsulfonyloxy (Ci-C8) - alkyl, (Ci-C 8) alkylsulfonyloxy (Ci-C8) alkyl, Hydrothio- (Ci-C 8) alkyl, (Ci-C8) alkylthio (Ci-C 8) alkyl, (Ci-C 8) -Haloalkylthio- (Ci-C 8) alkyl, aryl ( Ci-Cs) -alkylthio (Ci-C 8) alkyl, (C 3 -C 8) cycloalkylthio (Ci-C 8) alkyl, arylthio (Ci-C 8) alkyl, (Ci-C 8 ) alkylsulfinyl (Ci-C 8) alkyl, (Ci-C 8) - alkylsulfonyl (Ci-C 8) alkyl, (Ci-C 8) -Haloalkylsulfinyl- (Ci-C 8) alkyl,
    (Ci-C 8 )-Haloalkylsulfonyl-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkylsulfinyl- (Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkylsulfonyl-(Ci-C 8 )-alkyl, (C 3 -C 8 )- Cycloalkylsulfinyl-(Ci-C 8 )-alkyl, (C3-C8)-Cycloalkylsulfonyl-(Ci-C 8 )-alkyl, Aryl, Heteroaryl, Heterocyclyl, N-[(Ci-C 8 )-Alkyl]heterocyclyl, N-[(Ci-C 8 )- Alkoxycarbonyl]heterocyclyl, N-[Aryl-(Ci-Cs)- alkoxycarbonyl]heterocyclyl, N-(Arylcarbonyl)heterocyclyl, N-[(Ci-C8)- Alkylcarbonyl]heterocyclyl, N-[(Ci-C8)-Cycloalkylcarbonyl]heterocyclyl, Hydroxycarbonyl, (Ci-C8)-Alkoxycarbonyl, (C3-C8)- Cycloalkoxycarbonyl, (C3-C8)-Cycloalkyl-(Ci-C8)-alkoxycarbonyl, Aryl- (Ci-C8)-alkoxycarbonyl, Heteroaryl-(Ci-C8)-alkoxycarbonyl, (Ci-Cs)- Alkylaminocarbonyl, Aminocarbonyl, Bis-(Ci-C8)-alkylaminocarbonyl, (C3-C8)-Cycloalkylaminocarbonyl, Aryl-(Ci-C8)-alkylaminocarbonyl, Heteroarylaminocarbonyl, Cyano-(Ci-C8)-alkylaminocarbonyl, (Ci-Cs)- Haloalkylaminocarbonyl, (C2-C8)-Alkinyl-(Ci-C8)-alkylaminocarbonyl, Hydroxycarbonyl-(Ci-C8)-alkyl, (Ci-C8)-Alkoxycarbonyl-(Ci-C8)-alkyl, (C3-C 8 )-Cycloalkoxycarbonyl-(Ci-C 8 )-alkyl, (C3-C 8 )-Cycloalkyl-(Ci-C 8 )- alkoxycarbonyl-(Ci-C8)-alkyl, Aryl-(Ci-C8)-alkoxycarbonyl-(Ci-C8)-alkyl, Heteroaryl-(Ci-C8)-alkoxycarbonyl-(Ci-C8)-alkyl, (Ci-Cs)- Alkylaminocarbonyl-(Ci-C8)-alkyl, Aminocarbonyl-(Ci-C8)-alkyl, Bis- (Ci-C 8 )-alkylaminocarbonyl-(Ci-C 8 )-alkyl, (C 3 -C 8 )- Cycloalkylaminocarbonyl-(Ci-C8)-alkyl, Aryl-(Ci-Cs)- alkylaminocarbonyl-(Ci-C8)-alkyl, Heteroarylaminocarbonyl-(Ci-C8)- alkyl, Cyano-(Ci-C8)-alkylaminocarbonyl-(Ci-C8)-alkyl, (Ci-Cs)- Haloalkylaminocarbonyl-(Ci-C 8 )-alkyl, (C2-C 8 )-Alkinyl-(Ci-C 8 )- alkylaminocarbonyl-(Ci-C8)-alkyl, Amino-(Ci-C8)-alkyl, (Ci-Cs)- Alkylamino-(Ci-C 8 )-alkyl, (C2-C 8 )-Alkenylamino-(Ci-C 8 )-alkyl, (Ci-C 8) -Haloalkylsulfonyl- (Ci-C 8) alkyl, aryl (Ci-C8) alkylsulfinyl (Ci-C 8) alkyl, aryl (Ci-C8) alkylsulfonyl ( Ci-C 8) alkyl, (C 3 -C 8) - Cycloalkylsulfinyl- (Ci-C 8) alkyl, (C3-C8) -Cycloalkylsulfonyl- (Ci-C 8) alkyl, aryl, heteroaryl, heterocyclyl, N - [(Ci-C 8) -alkyl] heterocyclyl, N - [(Ci-C8) - alkoxycarbonyl] heterocyclyl, N- [aryl- (Ci-Cs) - alkoxycarbonyl] heterocyclyl, N- (arylcarbonyl) heterocyclyl, N - [(Ci-C8) - alkyl carbonyl] heterocyclyl, N - [(Ci-C8) -cycloalkylcarbonyl] heterocyclyl, hydroxycarbonyl, (Ci-C8) -alkoxycarbonyl, (C3-C8) - cycloalkoxycarbonyl, (C3-C8) - cycloalkyl- (Ci-C8) -alkoxycarbonyl, aryl (Ci-C8) -alkoxycarbonyl, heteroaryl (Ci-C8) -alkoxycarbonyl, (Ci-Cs) - alkylaminocarbonyl, aminocarbonyl, bis (Ci-C8) alkylaminocarbonyl, (C3-C8) cycloalkylaminocarbonyl, aryl (Ci-C8) alkylaminocarbonyl, heteroarylaminocarbonyl, cyano (Ci-C8) alkylaminocarbonyl, (Ci-Cs) - Haloalkylaminocarbonyl, (C2-C8) alkynyl (Ci-C8 ) alkylaminocarbonyl, hydroxycarbonyl (Ci-C8) alkyl, (Ci-C8) -alkoxycarbonyl (Ci-C8) alkyl, (C3-C8) -Cycloalkoxycarbonyl- (Ci-C8) alkyl, (C3 C8) cycloalkyl- (Ci-C 8) - alkoxycarbonyl (Ci-C8) alkyl, aryl (Ci-C8) -alkoxycarbonyl (Ci-C8) alkyl, heteroaryl (Ci-C8) - alkoxycarbonyl- (Ci-C8) alkyl, (Ci-Cs) - alkylaminocarbonyl (Ci-C8) alkyl, aminocarbonyl (Ci-C8) alkyl, bis (Ci-C 8) alkylaminocarbonyl (CI- C 8) alkyl, (C 3 -C 8) - cycloalkylaminocarbonyl (Ci-C8) alkyl, aryl (Ci-Cs) - alkylaminocarbonyl (Ci-C8) alkyl, Heteroarylaminocarbonyl- (Ci-C8) - alkyl, cyano- (Ci-C8) alkylaminocarbonyl (Ci-C8) alkyl, (Ci-Cs) - Haloalkylaminocarbonyl- (Ci-C 8) alkyl, (C2-C8) alkynyl (Ci-C 8) - alkylaminocarbonyl (Ci-C8) alkyl, amino (Ci-C8) alkyl, (Ci-Cs) - alkylamino (Ci-C 8) alkyl, (C2-C8) -Alkenylamino- ( Ci-C 8) alkyl,
    Arylamino-(Ci-C 8 )-alkyl, Bis-(Ci-C 8 )-alkylamino-(Ci-C 8 )-alkyl, Bis- (C 3 -C 8 )-cycloalkylamino-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkylamino-(Ci-C 8 )- alkyl, Tris-Aryl-(Ci-C 8 )-alkylamino-(Ci-C 8 )-alkyl, (C 3 -C 8 )- Cycloalkylamino-(Ci-C 8 )-alkyl, (C3-C 8 )-Cycloalkyl-(Ci-C 8 )-alkylamino- (Ci-Cs)-alkyl, (Ci-C 8 )-Haloalkylamino-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkylcarbonylamino-(Ci-C 8 )-alkyl, (Ci-C 8 )-Cycloalkylcarbonylamino- (Ci-C 8 )-alkyl, Arylcarbonylamino-(Ci-C 8 )-alkyl, Arylamino (Ci-C 8) alkyl, bis (Ci-C 8) alkylamino (Ci-C8) alkyl, bis (C 3 -C 8) cycloalkylamino (Ci-C 8) - alkyl, aryl (Ci-C 8) alkylamino (Ci-C 8) - alkyl, Tris-aryl (Ci-C 8) alkylamino (Ci-C 8) alkyl, (C 3 -C 8 ) - cycloalkylamino (Ci-C 8) alkyl, (C3-C8) cycloalkyl (Ci-C 8) alkylamino (Ci-Cs) alkyl, (Ci-C 8) -Haloalkylamino- (Ci -C 8) alkyl, (Ci-C 8) - alkylcarbonylamino (Ci-C 8) alkyl, (Ci-C 8) -Cycloalkylcarbonylamino- (Ci-C 8) alkyl, arylcarbonylamino (Ci-C 8 ) alkyl,
    Heteroarylcarbonylamino-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkoxycarbonylamino- (Ci-C 8 )-alkyl, (C2-C 8 )-Alkenyloxycarbonylamino-(Ci-C 8 )-alkyl, Aryl- (Ci-C 8 )-alkoxycarbonylamino-(Ci-C 8 )-alkyl, Aryl-(Ci-Cs)- alkoxycarbonyl[N-(Ci-C 8 )-alkyl]amino-(Ci-C 8 )-alkyl, Heteroaryl-(Ci-Cs)- alkoxycarbonylamino-(Ci-C 8 )-alkyl, (C3-C 8 )-Cycloalkyl-(Ci-C 8 )- alkoxycarbonylamino-(Ci-C 8 )-alkyl, (C3-C 8 )-Cycloalkoxycarbonylamino- (Ci-C 8 )-alkyl, Aminocarbonylamino-(Ci-C 8 )-alkyl, Arylsulfonylamino- (Ci-C 8 )-alkyl, Heteroarylsulfonylamino-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkylsulfonylamino-(Ci-C 8 )-alkyl, (C3-C 8 )-Cycloalkylsulfonylamino- (Ci-C 8 )-alkyl, Aminoiminoamino-(Ci-C 8 )-alkyl, Heteroarylcarbonylamino- (Ci-C 8) alkyl, (Ci-C8) alkoxycarbonylamino (Ci-C 8) alkyl, (C2-C8) -Alkenyloxycarbonylamino- (Ci-C 8) alkyl, aryl ( Ci-C8) alkoxycarbonylamino (Ci-C 8) alkyl, aryl (Ci-Cs) - alkoxycarbonyl [N- (Ci-C 8) alkyl] amino- (Ci-C 8) alkyl, heteroaryl - (Ci-Cs) - alkoxycarbonylamino (Ci-C 8) alkyl, (C3-C8) cycloalkyl (Ci-C 8) - alkoxycarbonylamino (Ci-C 8) alkyl, (C3-C 8 ) -Cycloalkoxycarbonylamino- (Ci-C 8) alkyl, aminocarbonylamino (Ci-C 8) alkyl, arylsulfonylamino (Ci-C 8) alkyl, Heteroarylsulfonylamino- (Ci-C 8) alkyl, (Ci-C 8) - alkylsulfonylamino (Ci-C 8) alkyl, (C3-C 8) -Cycloalkylsulfonylamino- (Ci-C 8) alkyl, Aminoiminoamino- (Ci-C 8) alkyl,
    Arylsulfonylaminoiminoamino-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkylaminoiminoamino-(Ci-C 8 )-alkyl steht, für Wasserstoff, Halogen, (Ci-Cs)-Alkyl, (Ci-Cs)-Alkoxy, (Ci-C 8 )- Alkoxycarbonyloxy, (C 2 -C 8 )-Alkenyl, (C 2 -C 8 )-Haloalkenyl, (C 2 -C 8 )- Alkenyl-(Ci-C 8 )-alkyl, (C 2 -C 8 )-Alkinyl, (C 2 -C 8 )-Alkinyl-(Ci-C 8 )-alkyl, Aryl- (Ci-Cs)-alkyl, Bisaryl-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkoxyaryl-(Ci-C 8 )- alkyl, Aryloxyaryl-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkoxyaryl-(Ci-C 8 )-alkyl, Heteroaryl-(Ci-C 8 )-alkyl, Heterocyclyl-(Ci-C 8 )-alkyl, N-(Ci-C 8 )- Alkylheterocyclyl-(Ci-C 8 )-alkyl, N-[(Ci-C 8 )-Alkoxycarbonyl]heterocyclyl- (Ci-Cs)-alkyl, N-(Aryl-(Ci-C 8 )-alkoxycarbonyl)heterocyclyl-(Ci-C 8 )-alkyl, N-(Arylcarbonyl)heterocyclyl-(Ci-C 8 )-alkyl, N-[(Ci-C 8 )- Arylsulfonylaminoiminoamino- (Ci-C 8) alkyl, (Ci-C 8) - Alkylaminoiminoamino- (Ci-C 8) alkyl, represents hydrogen, halogen, (Ci-Cs) alkyl, (Ci-Cs) alkoxy , (Ci-C 8) - alkoxycarbonyloxy, (C 2 -C 8) -alkenyl, (C 2 -C 8) haloalkenyl, (C 2 -C 8) - alkenyl, (Ci-C 8) alkyl, ( C 2 -C 8) -alkynyl, (C 2 -C 8) alkynyl (Ci-C 8) alkyl, aryl (Ci-Cs) alkyl, bisaryl (Ci-C 8) alkyl, aryl - (Ci-C 8) -alkoxyaryl- (Ci-C 8) - alkyl, Aryloxyaryl- (Ci-C 8) alkyl, (Ci-C 8) -Alkoxyaryl- (Ci-C 8) alkyl, heteroaryl- (Ci-C 8) alkyl, heterocyclyl (Ci-C 8) -alkyl, N- (Ci-C 8) - Alkylheterocyclyl- (Ci-C 8) -alkyl, N - [(Ci-C 8) - alkoxycarbonyl] heterocyclyl (Ci-Cs) alkyl, N- (aryl (Ci-C8) alkoxycarbonyl) heterocyclyl- (Ci-C 8) alkyl, N- (arylcarbonyl) heterocyclyl- (Ci-C 8) alkyl, N - [(Ci-C 8) -
    Alkylcarbonyl]heterocyclyl-(Ci-C 8 )-alkyl, N-[(C 3 -C 8 )- Cycloalkylcarbonyl]heterocyclyl-(Ci-C 8 )-alkyl, Cyano-(Ci-C 8 )-alkyl, (Ci-Ce)-Haloalkyl, (C 3 -C 8 )-Cycloalkyl, (C 3 -C 8 )-Halocycloalkyl, (C 4 -C 8 )- Cycloalkenyl, (C 3 -C8)-Cycloalkyl-(Ci-C 8 )-alkyl, (C 3 -C 8 )-Cycloalkenyl- (Ci-Cs)-alkyl, Hydroxy-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkoxy-(Ci-C 8 )-alkyl, Alkylcarbonyl] heterocyclyl (Ci-C 8) -alkyl, N - [(C 3 -C 8) - cycloalkylcarbonyl] heterocyclyl (Ci-C8) alkyl, cyano (Ci-C 8) alkyl, (C -ce) -haloalkyl, (C 3 -C 8) -cycloalkyl, (C 3 -C 8) halocycloalkyl, (C 4 -C 8) - cycloalkenyl, (C 3 -C 8) cycloalkyl (Ci-C 8 ) alkyl, (C 3 -C 8) cycloalkenyl (Ci-Cs) alkyl, hydroxy (Ci-C 8) alkyl, (Ci-C 8) alkoxy (Ci-C 8) alkyl .
    (Ci-C 8 )-Haloalkoxy-(Ci-C 8 )-alkyl, Aryloxy-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )- alkoxy-(Ci-C 8 )-alkyl, Heteroaryl-(Ci-C 8 )-alkoxy-(Ci-C 8 )-alkyl, (C 3 -C 8 )- Cycloalkoxy-(Ci-C 8 )-alkyl, (C 3 -C 8 )-Cycloalkyl-(Ci-C 8 )-alkoxy-(Ci-C 8 )- alkyl, (Ci-C 8 )-Alkylcarbonyloxy-(Ci-C 8 )-alkyl, Arylcarbonyloxy-(Ci-C 8 )- alkyl, Heteroarylcarbonyloxy-(Ci-C 8 )-alkyl, -(C 3 -C 8 )- Cycloalkylcarbonyloxy-(Ci-C 8 )-alkyl, Arylsulfonyloxy-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkylsulfonyloxy-(Ci-C 8 )-alkyl, Hydrothio-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkylthio-(Ci-C 8 )-alkyl, (Ci-C 8 )-Haloalkylthio-(Ci-C 8 )-alkyl, Aryl-(Ci-Cs)- alkylthio-(Ci-C 8 )-alkyl, -(C 3 -C 8 )-Cycloalkylthio-(Ci-C 8 )-alkyl, Arylthio- (Ci-Cs)-alkyl, (Ci-C 8 )-Alkylsulfinyl-(Ci-C 8 )-alkyl, (Ci-Cs)-Alkylsulfonyl- (Ci-Cs)-alkyl, (Ci-C 8 )-Haloalkylsulfinyl-(Ci-C 8 )-alkyl, (Ci-C 8 )- Haloalkylsulfonyl-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkylsulfinyl-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkylsulfonyl-(Ci-C 8 )-alkyl, (C 3 -C 8 )-Cycloalkylsulfinyl- (Ci-Cs)-alkyl, (C 3 -C 8 )-Cycloalkylsulfonyl-(Ci-C 8 )-alkyl, Aryl, Heteroaryl, Heterocyclyl, N-[(Ci-C 8 )-Alkyl]heterocyclyl, N-[(Ci-C 8 )- Alkoxycarbonyl]heterocyclyl, N-[Aryl-(Ci-C 8 )- alkoxycarbonyl]heterocyclyl, N-(Arylcarbonyl)heterocyclyl, N-[(Ci-C 8 )- Alkylcarbonyl]heterocyclyl, N-[(Ci-C 8 )-Cycloalkylcarbonyl]heterocyclyl, Hydroxycarbonyl, (Ci-Cs)-Alkoxycarbonyl, (C 3 -C 8 )- Cycloalkoxycarbonyl, (C 3 -C 8 )-Cycloalkyl-(Ci-C 8 )-alkoxycarbonyl, Aryl- (Ci-C 8 )-alkoxycarbonyl, Heteroaryl-(Ci-C 8 )-alkoxycarbonyl, (Ci-C 8 )- Alkylaminocarbonyl, Aminocarbonyl, Bis-(Ci-C 8 )-alkylaminocarbonyl, (C 3 -C 8 )-Cycloalkylaminocarbonyl, Aryl-(Ci-C 8 )-alkylaminocarbonyl, Heteroarylaminocarbonyl, Cyano-(Ci-C 8 )-alkylaminocarbonyl, (Ci-C 8 )- Haloalkylaminocarbonyl, (C2-C 8 )-Alkinyl-(Ci-C 8 )-alkylaminocarbonyl, Hydroxycarbonyl-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkoxycarbonyl-(Ci-C 8 )-alkyl, (C 3 -C 8 )-Cycloalkoxycarbonyl-(Ci-C 8 )-alkyl, (C 3 -C 8 )-Cycloalkyl-(Ci-C 8 )- alkoxycarbonyl-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkoxycarbonyl-(Ci-C 8 )-alkyl, Heteroaryl-(Ci-C 8 )-alkoxycarbonyl-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkylaminocarbonyl-(Ci-C8)-alkyl, Aminocarbonyl-(Ci-C8)-alkyl, Bis- (Ci-C 8 )-alkylaminocarbonyl-(Ci-C 8 )-alkyl, (C 3 -C 8 )- Cycloalkylaminocarbonyl-(Ci-C8)-alkyl, Aryl-(Ci-Cs)- alkylaminocarbonyl-(Ci-C8)-alkyl, Heteroarylaminocarbonyl-(Ci-C 8 )- alkyl, Cyano-(Ci-C8)-alkylaminocarbonyl-(Ci-C8)-alkyl, (Ci-C 8 )- Haloalkylaminocarbonyl-(Ci-C 8 )-alkyl, -(C2-C 8 )-Alkinyl-(Ci-C 8 )- alkylaminocarbonyl-(Ci-C 8 )-alkyl, Amino-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkylamino-(Ci-C 8 )-alkyl, (C2-C 8 )-Alkenylamino-(Ci-C 8 )-alkyl, (Ci-C 8) haloalkoxy (Ci-C 8) alkyl, aryloxy (Ci-C8) alkyl, aryl (Ci-C 8) - alkoxy- (Ci-C 8) alkyl, heteroaryl - (Ci-C 8) alkoxy (Ci-C 8) alkyl, (C 3 -C 8) - cycloalkoxy (Ci-C 8) alkyl, (C 3 -C 8) cycloalkyl (C -C 8) alkoxy (Ci-C 8) - alkyl, (Ci-C8) alkylcarbonyloxy (Ci-C 8) alkyl, arylcarbonyloxy (Ci-C 8) - alkyl, Heteroarylcarbonyloxy- (Ci- C 8) alkyl, - (C 3 -C 8) - Cycloalkylcarbonyloxy- (Ci-C 8) alkyl, arylsulfonyloxy (Ci-C 8) alkyl, (Ci-C 8) alkylsulfonyloxy (Ci-C 8) -alkyl, Hydrothio- (Ci-C 8) alkyl, (Ci-C 8) - alkylthio- (Ci-C 8) alkyl, (Ci-C 8) -Haloalkylthio- (Ci-C 8) - alkyl, aryl (Ci-Cs) - alkylthio- (Ci-C 8) alkyl, - (C 3 -C 8) cycloalkylthio (Ci-C 8) alkyl, arylthio (Ci-Cs) alkyl , (Ci-C8) alkylsulfinyl (Ci-C 8) alkyl, (Ci-Cs) alkylsulfonyl (Ci-Cs) alkyl, (Ci-C 8) -Haloalkylsulfinyl- (Ci-C 8) alkyl, (Ci-C 8) - Haloalkylsulfonyl- (Ci-C 8) alkyl, aryl (Ci-C8) alkylsulfinyl (Ci-C 8) alkyl, aryl (Ci-C 8) - alkylsulfonyl (Ci-C 8) alkyl, (C 3 -C 8) -Cycloalkylsulfinyl- (Ci-Cs) alkyl, (C 3 -C 8) -Cycloalkylsulfonyl- (Ci-C 8) alkyl, aryl, heteroaryl, heterocyclyl, N - [(Ci-C 8) -alkyl] heterocyclyl, N - [(Ci-C8) - alkoxycarbonyl] heterocyclyl, N- [aryl (Ci-C8) - alkoxycarbonyl] heterocyclyl, N- (arylcarbonyl) heterocyclyl, N - [(Ci-C 8) - alkylcarbonyl] heterocyclyl, N - [(Ci-C 8) -cycloalkylcarbonyl] heterocyclyl, hydroxycarbonyl, (Ci-Cs) -alkoxycarbonyl, (C 3 -C 8) - cycloalkoxycarbonyl, (C 3 -C 8) cycloalkyl (Ci-C8) alkoxycarbonyl, aryl (Ci-C8) alkoxycarbonyl, heteroaryl- (Ci-C8) alkoxycarbonyl, (Ci-C 8) - alkylaminocarbonyl, aminocarbonyl, bis (Ci-C 8) alkylaminocarbonyl, (C 3 -C 8) cycloalkylaminocarbonyl, aryl (Ci-C 8) alkylaminocarbonyl, heteroarylaminocarbonyl, cyano, (Ci-C 8) alkylaminocarbonyl, (Ci-C 8) - Haloalkylaminocarbonyl, (C2-C8) alkynyl (Ci-C 8) alkylaminocarbonyl, hydroxycarbonyl (Ci-C 8) alkyl, (Ci-C8) alkoxycarbonyl (CI- C 8) alkyl, (C 3 -C 8) -Cycloalkoxycarbonyl- (Ci-C 8) alkyl, (C 3 -C 8) cycloalkyl (Ci-C8) - alkoxycarbonyl (Ci-C 8) alkyl, aryl (Ci-C8) alkoxycarbonyl (Ci-C 8) alkyl, heteroaryl (Ci-C8) alkoxycarbonyl (Ci-C 8) alkyl, (Ci-C 8) - alkylaminocarbonyl (Ci-C8) alkyl, aminocarbonyl (Ci-C8) alkyl, bis (Ci-C 8) alkylaminocarbonyl (Ci-C8) alkyl, (C 3 -C 8) - cycloalkylaminocarbonyl (Ci-C8) alkyl, aryl (Ci-Cs) - alkylaminocarbonyl (Ci-C8) alkyl, Heteroarylaminocarbonyl- (Ci-C 8) - alkyl, cyano (Ci-C8) alkylaminocarbonyl (Ci C8) alkyl, (Ci-C 8) - Haloalkylaminocarbonyl- (Ci-C 8) alkyl, - (C2-C8) alkynyl (Ci-C 8) - alkylaminocarbonyl (Ci-C 8) alkyl , amino (Ci-C 8) alkyl, (Ci-C8) - alkylamino (Ci-C 8) alkyl, (C2-C8) -Alkenylamino- (Ci-C 8) alkyl,
    Arylamino-(Ci-C 8 )-alkyl, Bis-(Ci-C 8 )-alkylamino-(Ci-C 8 )-alkyl, Bis- (C 3 -C 8 )-cycloalkylamino-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkylamino-(Ci-C 8 )- alkyl, Tris-Aryl-(Ci-C 8 )-alkylamino-(Ci-C 8 )-alkyl, (C 3 -C 8 )- Cycloalkylamino-(Ci-C 8 )-alkyl, (C3-C 8 )-Cycloalkyl-(Ci-C 8 )-alkylamino- (Ci-Cs)-alkyl, (Ci-C 8 )-Haloalkylamino-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkylcarbonylamino-(Ci-C 8 )-alkyl, (Ci-C 8 )-Cycloalkylcarbonylamino- (Ci-C 8 )-alkyl, Arylcarbonylamino-(Ci-C 8 )-alkyl, Arylamino (Ci-C 8) alkyl, bis (Ci-C 8) alkylamino (Ci-C8) alkyl, bis (C 3 -C 8) cycloalkylamino (Ci-C 8) - alkyl, aryl (Ci-C 8) alkylamino (Ci-C 8) - alkyl, Tris-aryl (Ci-C 8) alkylamino (Ci-C 8) alkyl, (C 3 -C 8 ) - cycloalkylamino (Ci-C 8) alkyl, (C3-C8) cycloalkyl (Ci-C 8) alkylamino (Ci-Cs) alkyl, (Ci-C 8) -Haloalkylamino- (Ci -C 8) alkyl, (Ci-C 8) - alkylcarbonylamino (Ci-C 8) alkyl, (Ci-C 8) -Cycloalkylcarbonylamino- (Ci-C 8) alkyl, arylcarbonylamino (Ci-C 8 ) alkyl,
    Heteroarylcarbonylamino-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkoxycarbonylamino- (Ci-C 8 )-alkyl, (C2-C 8 )-Alkenyloxycarbonylamino-(Ci-C 8 )-alkyl, Aryl- (Ci-C 8 )-alkoxycarbonylamino-(Ci-C 8 )-alkyl, Aryl-(Ci-Cs)- alkoxycarbonyl[N-(Ci-C 8 )-alkyl]amino-(Ci-C 8 )-alkyl, Heteroaryl-(Ci-Cs)- alkoxycarbonylamino-(Ci-C 8 )-alkyl, (C3-C 8 )-Cycloalkyl-(Ci-C 8 )- alkoxycarbonylamino-(Ci-C 8 )-alkyl, (C3-C 8 )-Cycloalkoxycarbonylamino- (Ci-C 8 )-alkyl, Aminocarbonylamino-(Ci-C 8 )-alkyl, Arylsulfonylamino- (Ci-C 8 )-alkyl, Heteroarylsulfonylamino-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkylsulfonylamino-(Ci-C 8 )-alkyl, (C3-C 8 )-Cycloalkylsulfonylamino- (Ci-C 8 )-alkyl, Aminoiminoamino-(Ci-C 8 )-alkyl, Heteroarylcarbonylamino- (Ci-C 8) alkyl, (Ci-C8) alkoxycarbonylamino (Ci-C 8) alkyl, (C2-C8) -Alkenyloxycarbonylamino- (Ci-C 8) alkyl, aryl ( Ci-C8) alkoxycarbonylamino (Ci-C 8) alkyl, aryl (Ci-Cs) - alkoxycarbonyl [N- (Ci-C 8) alkyl] amino- (Ci-C 8) alkyl, heteroaryl - (Ci-Cs) - alkoxycarbonylamino (Ci-C 8) alkyl, (C3-C8) cycloalkyl (Ci-C 8) - alkoxycarbonylamino (Ci-C 8) alkyl, (C3-C 8 ) -Cycloalkoxycarbonylamino- (Ci-C 8) alkyl, aminocarbonylamino (Ci-C 8) alkyl, arylsulfonylamino (Ci-C 8) alkyl, Heteroarylsulfonylamino- (Ci-C 8) alkyl, (Ci-C 8) - alkylsulfonylamino (Ci-C 8) alkyl, (C3-C 8) -Cycloalkylsulfonylamino- (Ci-C 8) alkyl, Aminoiminoamino- (Ci-C 8) alkyl,
    Arylsulfonylaminoiminoamino-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkylaminoiminoamino-(Ci-C 8 )-alkyl steht, 8 unabhängig voneinander für H, (Ci-Cs)-Alkyl, (C2-C 8 )-Alkenyl- (Ci-Cs)-alkyl, (C 2 -C 8 )-Alkinyl-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkyl, (C 3 -C 8 )- Arylsulfonylaminoiminoamino- (Ci-C 8) alkyl, (Ci-C 8) - Alkylaminoiminoamino- (Ci-C 8) -alkyl, 8 independently of one another H, (Ci-Cs) alkyl, (C2-C8) alkenyl (Ci-Cs) alkyl, (C 2 -C 8) alkynyl (Ci-C 8) alkyl, aryl (Ci-C 8) alkyl, (C 3 -C 8) -
    Cycloalkyl, (C3-C 8 )-Cycloalkyl-(Ci-C 8 )-alkyl, Heterocyclyl, Heterocyclyl- (Ci-Cs)-alkyl, Amino-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkoxy-(Ci-C 8 )-alkyl, (Ci-Ce)-Alkylthio-(Ci-C 8 )-alkyl, (Ci-C 8 )-Haloalkyl, (Ci-C 8 )-Alkylamino- (Ci-Ce)-alkyl, Bis-(Ci-C 8 )-alkylamino-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkylcarbonylamino-(Ci-C 8 )-alkyl, (C3-C 8 )-Cycloalkylcarbonylamino- (Ci-Cs)-alkyl, Arylcarbonylamino-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkoxycarbonylamino-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkoxycarbonylamino- (Ci-Cs)-alkyl, (C 3 -C8)-Cycloalkyl-(Ci-C8)-alkoxycarbonylamino-(Ci-C 8 )- alkyl, Aminocarbonylamino-(Ci-C8)-alkyl, Aminoiminoamino-(Ci-C8)- alkyl, Arylsulfonylaminoiminoamino-(Ci-C8)-alkyl, (Ci-Cs)- Alkylaminoiminoamino-(Ci-C8)-alkyl stehen, für H, (Ci-C 8 )-Alkyl, (C 2 -C8)-Alkenyl-(Ci-C 8 )-alkyl, (C 2 -C 8 )-Alkinyl, Cycloalkyl, (C3-C8) cycloalkyl (Ci-C 8) alkyl, heterocyclyl, heterocyclyl (Ci-Cs) alkyl, amino (Ci-C 8) alkyl, (Ci-C 8) - alkoxy (Ci-C 8) alkyl, (Ci-Ce) alkylthio (Ci-C 8) alkyl, (Ci-C 8) haloalkyl, (Ci-C 8) alkylamino (Ci-Ce ) alkyl, bis (Ci-C 8) alkylamino (Ci-C 8) alkyl, (Ci-C 8) - alkylcarbonylamino (Ci-C 8) alkyl, (C3-C 8) -Cycloalkylcarbonylamino - (Ci-Cs) alkyl, arylcarbonylamino (Ci-C 8) alkyl, (Ci-C 8) - alkoxycarbonylamino (Ci-C 8) alkyl, aryl (Ci-C8) alkoxycarbonylamino ( Ci-Cs) alkyl, (C 3 -C 8) cycloalkyl (Ci-C8) alkoxycarbonylamino (Ci-C 8) - alkyl, aminocarbonylamino (Ci-C8) alkyl, Aminoiminoamino- (Ci-C8) - alkyl, Arylsulfonylaminoiminoamino- (Ci-C8) alkyl, (Ci-Cs) - Alkylaminoiminoamino- (Ci-C8) alkyl, H, (Ci-C8) alkyl, (C 2 -C 8) alkenyl - (Ci-C 8) alkyl, (C 2 -C 8) alkynyl,
    (Ci-C8)-Alkylcarbonyl, (C3-C8)-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl, (Ci-C8)-Alkoxycarbonyl, Aryl-(Ci-Cs)- alkoxycarbonyl, (C3-C8)-Cycloalkoxycarbonyl, (C3-C8)-Cycloalkyl- (Ci-C 8 )-alkoxycarbonyl, (Ci-C 8 )-Alkylsulfonyl, (C 3 -C 8 )- Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C8)-Alkoxycarbonylcarbonyl, Aryl- (Ci-C8)-alkoxycarbonylcarbonyl, (Ci-C8)-Alkylaminothiocarbonyl, (Ci-C8) alkylcarbonyl, (C3-C8) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl, (Ci-C8) -alkoxycarbonyl, aryl (Ci-Cs) - alkoxycarbonyl, (C3-C8) cycloalkoxycarbonyl, (C3-C8 ) cycloalkyl (Ci-C8) alkoxycarbonyl, (Ci-C8) alkylsulfonyl, (C 3 -C 8) - cycloalkylsulfonyl, arylsulfonyl, (Ci-C8) -Alkoxycarbonylcarbonyl, aryl (Ci-C8) - alkoxycarbonylcarbonyl, (Ci-C8) -Alkylaminothiocarbonyl,
    (Ci-C 8 )-Alkylaminocarbonyl, Aryl-(Ci-C 8 )-alkyl, Hetaroaryl-(Ci-C 8 )-alkyl, Cyano-(Ci-C 8 )-alkyl, (Ci-C 8 )-Haloalkyl, (C 3 -C 8 )-Cycloalkyl, (C 3 -C 8 )- Cycloalkyl-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkoxy-(Ci-C 8 )-alkyl, (Ci-C 8 )- Haloalkoxy-(Ci-C 8 )-alkyl, (C 2 -C8)-Alkinyl-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkoxycarbonyl-(Ci-C8)-alkyl, Aminocarbonyl-(Ci-C8)-alkyl, (Ci-Cs)- Alkylaminocarbonyl-(Ci-C8)-alkyl, Bis-(Ci-C8)-alkylaminocarbonyl- (Ci-C 8 )-alkyl steht, (Ci-C 8) alkylaminocarbonyl, aryl (Ci-C 8) alkyl, Hetaroaryl- (Ci-C 8) -alkyl, cyano- (Ci-C 8) alkyl, (Ci-C8) -haloalkyl , (C 3 -C 8) -cycloalkyl, (C 3 -C 8) - cycloalkyl, (Ci-C 8) alkyl, (Ci-C 8) alkoxy (Ci-C 8) alkyl, (C -C 8) - haloalkoxy (Ci-C 8) alkyl, (C 2 -C 8) alkynyl (Ci-C 8) alkyl, (Ci-C8) - alkoxycarbonyl (Ci-C8) alkyl , aminocarbonyl (Ci-C8) alkyl, (Ci-Cs) - alkylaminocarbonyl (Ci-C8) alkyl, bis (Ci-C8) alkylaminocarbonyl (Ci-C 8) -alkyl,
    im Falle der Gruppierung Q-21 ausschließlich für H oder Methyl steht für (C 2 -C 8 )-Alkyl, (C 2 -C 8 )-Alkenyl-(Ci-C 8 )-alkyl, (C 2 -C 8 )-Alkinyl, (Ci-C 8 )- Alkylcarbonyl, (C3-C8)-Cycloalkylcarbonyl, Arylcarbonyl, in the case of the group Q-21 exclusively for H or methyl is (C 2 -C 8) alkyl, (C 2 -C 8) alkenyl (Ci-C 8) alkyl, (C 2 -C 8) -alkynyl, (C 8) - alkylcarbonyl, (C3-C8) cycloalkylcarbonyl, arylcarbonyl,
    Heteroarylcarbonyl, (Ci-C8)-Alkoxycarbonyl, Aryl-(Ci-Cs)- alkoxycarbonyl, (C3-C8)-Cycloalkoxycarbonyl, (C3-C8)-Cycloalkyl- Heteroarylcarbonyl, (Ci-C8) -alkoxycarbonyl, aryl (Ci-Cs) - alkoxycarbonyl, (C3-C8) cycloalkoxycarbonyl, (C3-C8) cycloalkyl-
    (Ci-C 8 )-alkoxycarbonyl, (Ci-C 8 )-Alkylsulfonyl, (C 3 -C 8 )- Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C8)-Alkoxycarbonylcarbonyl, Aryl- (Ci-C8)-alkoxycarbonylcarbonyl, (Ci-C8)-Alkylaminothiocarbonyl, (Ci-Ce)-Alkylaminocarbonyl, Aryl-(Ci-C 8 )-alkyl, Hetaroaryl-(Ci-C 8 )-alkyl, Cyano-(Ci-C 8 )-alkyl, (Ci-C 8 )-Haloalkyl, (C 3 -C 8 )-Cycloalkyl, (C 3 -C 8 )- Cycloalkyl-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkoxy-(Ci-C 8 )-alkyl, (Ci-C 8 )- Haloalkoxy-(Ci-C 8 )-alkyl, (C 2 -C8)-Alkinyl-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkoxycarbonyl-(Ci-C8)-alkyl, Aminocarbonyl-(Ci-C8)-alkyl, (Ci-Cs)- Alkylaminocarbonyl-(Ci-C8)-alkyl, Bis-(Ci-C8)-alkylaminocarbonyl- (Ci-C 8 )-alkyl steht, (Ci-C8) alkoxycarbonyl, (Ci-C8) alkylsulfonyl, (C 3 -C 8) - cycloalkylsulfonyl, arylsulfonyl, (Ci-C8) -Alkoxycarbonylcarbonyl, aryl (Ci-C8) -alkoxycarbonylcarbonyl, (C C8) -Alkylaminothiocarbonyl, (Ci-Ce) alkylaminocarbonyl, aryl (Ci-C 8) alkyl, Hetaroaryl- (Ci-C 8) -alkyl, cyano- (Ci-C 8) alkyl, (Ci- C 8) haloalkyl, (C 3 -C 8) cycloalkyl, (C 3 -C 8) - cycloalkyl, (Ci-C 8) alkyl, (Ci-C 8) alkoxy (Ci-C 8) alkyl, (Ci-C 8) - haloalkoxy (Ci-C 8) alkyl, (C 2 -C 8) alkynyl (Ci-C 8) alkyl, (Ci-C8) - alkoxycarbonyl (C C8) alkyl, aminocarbonyl (Ci-C8) alkyl, (Ci-Cs) - alkylaminocarbonyl (Ci-C8) alkyl, bis (Ci-C8) alkylaminocarbonyl (Ci-C 8) alkyl stands,
    R 43 für H oder Methyl steht, R 43 is H or methyl,
    R 44 für Wasserstoff, (Ci-C 8 )-Alkyl, (C2-C 8 )-Alkenyl-(Ci-C 8 )-alkyl, (C 2 -C 8 )- Alkinyl, (Ci-C8)-Alkylcarbonyl, (C3-C8)-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl, (Ci-C8)-Alkoxycarbonyl, Aryl-(Ci-Cs)- alkoxycarbonyl, (C3-C8)-Cycloalkoxycarbonyl, (C 3 -C8)-Cycloalkyl- (Ci-C 8 )-alkoxycarbonyl, (Ci-C 8 )-Alkylsulfonyl, (C 3 -C 8 )- Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C8)-Alkoxycarbonylcarbonyl, Aryl- (Ci-C8)-alkoxycarbonylcarbonyl, (Ci-C8)-Alkylaminothiocarbonyl, (Ci-C 8 )-Alkylaminocarbonyl, Aryl-(Ci-C 8 )-alkyl, Hetaroaryl-(Ci-C 8 )-alkyl, Cyano-(Ci-C 8 )-alkyl, (Ci-C 8 )-Haloalkyl, (C 3 -C 8 )-Cycloalkyl, (C 3 -C 8 )- Cycloalkyl-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkoxy-(Ci-C 8 )-alkyl, (Ci-C 8 )- Haloalkoxy-(Ci-C 8 )-alkyl, (C2-C 8 )-Alkinyl-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkoxycarbonyl-(Ci-C8)-alkyl, Aminocarbonyl-(Ci-C8)-alkyl, (Ci-Cs)- Alkylaminocarbonyl-(Ci-C8)-alkyl, Bis-(Ci-C8)-alkylaminocarbonyl- (Ci-C 8 )-alkyl steht, R 44 is hydrogen, (Ci-C 8) alkyl, (C2-C8) alkenyl (Ci-C 8) alkyl, (C 2 -C 8) - alkynyl, (Ci-C8) alkylcarbonyl, (C3-C8) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl, (Ci-C8) -alkoxycarbonyl, aryl (Ci-Cs) - alkoxycarbonyl, (C3-C8) cycloalkoxycarbonyl, (C 3 -C 8) cycloalkyl- (Ci C 8) -alkoxycarbonyl, (Ci-C8) alkylsulfonyl, (C 3 -C 8) - cycloalkylsulfonyl, arylsulfonyl, (Ci-C8) -Alkoxycarbonylcarbonyl, aryl (Ci-C8) -alkoxycarbonylcarbonyl, (Ci-C8) -Alkylaminothiocarbonyl, (Ci-C 8) alkylaminocarbonyl, aryl (Ci-C 8) alkyl, Hetaroaryl- (Ci-C 8) -alkyl, cyano- (Ci-C 8) alkyl, (Ci-C 8 ) -haloalkyl, (C 3 -C 8) -cycloalkyl, (C 3 -C 8) - cycloalkyl, (Ci-C 8) alkyl, (Ci-C 8) alkoxy (Ci-C 8) alkyl , (Ci-C 8) - haloalkoxy (Ci-C 8) alkyl, (C2-C8) alkynyl (Ci-C 8) alkyl, (Ci-C8) - alkoxycarbonyl (Ci-C8 ) alkyl, aminocarbonyl (Ci-C8) alkyl, (Ci-Cs) - alkylaminocarbonyl (Ci-C8) alkyl, bis (Ci-C8) -alkylaminocarbonyl- is (Ci-C 8) alkyl,
    R 51 und R 71 unabhängig voneinander für Wasserstoff und Methyl stehen, R 51 and R 71 independently represent hydrogen and methyl,
    R 53 für Methyl steht, R 53 is methyl,
    R 61 und R 81 unabhängig voneinander für Wasserstoff und Methyl stehen, für H, Methyl steht R independently of one another 61 and R 81 represent hydrogen and methyl, is H, methyl
    R 64 , R 74 , R 84 unabhängig voneinander für Wasserstoff, Methyl stehen, wobei mindestens eine der Gruppen R 54 , R 64 , R 74 , R 84 für Methyl stehen muß, für Hydroxycarbonyl, (Ci-C8)-Alkoxycarbonyl, (C3-C8)- Cycloalkoxycarbonyl, (C3-C8)-Cycloalkyl-(Ci-C8)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C8)-alkoxycarbonyl, Aminocarbonyl, (Ci-Cs)- Alkylaminocarbonyl, Bis-(Ci-C8)-alkylaminocarbonyl, (Ci-Cs)- Alkyl[(Ci-C8)-Alkoxy]aminocarbonyl, (C3-C8)-Cycloalkylaminocarbonyl, Aryl-(Ci-C8)-alkylaminocarbonyl, Heteroaryl-(Ci-C8)- alkylaminocarbonyl, Cyano-(Ci-C8)-alkylaminocarbonyl, (Ci-Cs)- Haloalkylaminocarbonyl, (C2-C8)-Alkinyl-(Ci-C8)-alkylaminocarbonyl, (Ci-C8)-Alkoxycarbonyl-(Ci-C8)-alkylaminocarbonyl, Hydroxycarbonyl- (Ci-C8)-alkylaminocarbonyl, Aminocarbonyl-(Ci-C8)- alkylaminocarbonyl, (Ci-C8)-Alkylaminocarbonyl-(Ci-C8)- alkylaminocarbonyl, (C3-C8)-Cycloalkylaminocarbonyl-(Ci-C8)- alkylaminocarbonyl, (C3-C8)-Cycloalkyl-(Ci-C8)-alkylaminocarbonyl steht, für O, 1 , 2, 3, 4, 5 steht, für 1 , 2, 3, 4 steht, für Cyano, Cyano-(Ci-C 8 )-alkyl, Hydroxy-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkoxy- (Ci-C8)-alkyl, Hydroxycarbonyl, (Ci-C8)-Alkoxycarbonyl, (C3-C8)- Cycloalkoxycarbonyl, (C3-C8)-Cycloalkyl-(Ci-C8)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C8)-alkoxycarbonyl, Aminocarbonyl, (Ci-Cs)- Alkylaminocarbonyl, Bis-(Ci-C8)-alkylaminocarbonyl, (Ci-Cs)- Alkyl[(Ci-C8)-Alkoxy]aminocarbonyl, (C3-C8)-Cycloalkylaminocarbonyl, Aryl-(Ci-C8)-alkylaminocarbonyl, Heteroaryl-(Ci-C8)- alkylaminocarbonyl, Cyano-(Ci-C8)-alkylaminocarbonyl, (Ci-Cs)- Haloalkylaminocarbonyl, (C2-C8)-Alkinyl-(Ci-C8)-alkylaminocarbonyl, (Ci-C8)-Alkoxycarbonylaminocarbonyl, Aryl-(Ci-Cs)- alkoxycarbonylaminocarbonyl, Hydroxycarbonyl-(Ci-C8)-alkyl, (Ci-Cs)- Alkoxycarbonyl-(Ci-C8)-alkyl, (C3-C8)-Cycloalkoxycarbonyl-(Ci-C8)- alkyl, (C3-C8)-Cycloalkyl-(Ci-C8)-alkoxycarbonyl-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkylaminocarbonyl-(Ci-C8)-alkyl, Aminocarbonyl-(Ci-C8)-alkyl, Bis- (Ci-C 8 )-alkylaminocarbonyl-(Ci-C 8 )-alkyl, (C 3 -C 8 )- Cycloalkylaminocarbonyl-(Ci-C8)-alkyl, Aryl-(Ci-Cs)- alkylaminocarbonyl-(Ci-C8)-alkyl, Heteroaryl-(Ci-C8)- alkylaminocarbonyl-(Ci-C8)-alkyl, Cyano-(Ci-C8)-alkylaminocarbonyl- (Ci-C 8 )-alkyl, (Ci-C 8 )-Haloalkylaminocarbonyl-(Ci-C 8 )-alkyl, (C 2 -C 8 )- Alkinyl-(Ci-C8)-alkylaminocarbonyl-(Ci-C 8 )-alkyl, (C 3 -C 8 )-Cycloalkyl- (Ci-C 8 )-alkylaminocarbonyl-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkoxycarbonylaminocarbonyl-(Ci-C8)-alkyl, Aryl-(Ci-Cs)- alkoxycarbonylaminocarbonyl-(Ci-C8)-alkyl, R 64, R 74, R 84 are independently hydrogen, methyl, wherein at least one of the groups R 54, R 64, R 74, R 84 must be methyl, hydroxycarbonyl, (Ci-C8) alkoxycarbonyl, (C3 C8) - cycloalkoxycarbonyl, (C3-C8) cycloalkyl- (Ci-C8) alkoxycarbonyl, aryloxycarbonyl, aryl (Ci-C8) -alkoxycarbonyl, aminocarbonyl, (Ci-Cs) - alkylaminocarbonyl, bis (Ci-C8 ) alkylaminocarbonyl, (Ci-Cs) - alkyl [(Ci-C8) -alkoxy] aminocarbonyl, (C3-C8) cycloalkylaminocarbonyl, aryl (Ci-C8) alkylaminocarbonyl, heteroaryl (Ci-C8) - alkylaminocarbonyl, cyano (Ci-C8) alkylaminocarbonyl, (Ci-Cs) - Haloalkylaminocarbonyl, (C2-C8) alkynyl (Ci-C8) alkylaminocarbonyl, (Ci-C8) -alkoxycarbonyl (Ci-C8) alkylaminocarbonyl, hydroxycarbonyl (Ci-C8) alkylaminocarbonyl, aminocarbonyl (Ci-C8) - alkylaminocarbonyl, (Ci-C8) alkylaminocarbonyl (Ci-C8) - alkylaminocarbonyl, (C3-C8) -Cycloalkylaminocarbonyl- (Ci-C8) - alkylaminocarbonyl, (C3-C8) cycloalkyl (Ci-C8) alkylaminocarbonyl, represents O, 1, 2, 3, 4, 5, represents 1, 2, 3, 4, represents cyano, cyano (C -C 8) alkyl, hydroxy (Ci-C 8) alkyl, (Ci-C 8) alkoxy (Ci-C8) alkyl, hydroxycarbonyl, (Ci-C8) alkoxycarbonyl, (C3-C8) - cycloalkoxycarbonyl, (C3-C8) cycloalkyl- (Ci-C8) alkoxycarbonyl, aryloxycarbonyl, aryl (Ci-C8) -alkoxycarbonyl, aminocarbonyl, (Ci-Cs) - alkylaminocarbonyl, bis (Ci-C8) alkylaminocarbonyl (Ci-Cs) - alkyl [(Ci-C8) -alkoxy] aminocarbonyl, (C3-C8) cycloalkylaminocarbonyl, aryl (Ci-C8) alkylaminocarbonyl, heteroaryl (Ci-C8) - alkylaminocarbonyl, cyano ( Ci-C8) alkylaminocarbonyl, (Ci-Cs) - Haloalkylaminocarbonyl, (C2-C8) alkynyl (Ci-C8) alkylaminocarbonyl, (Ci-C8) -Alkoxycarbonylaminocarbonyl, aryl (Ci-Cs) - alkoxycarbonylaminocarbonyl, hydroxycarbonyl - (Ci-C8) alkyl, (Ci-Cs) - alkoxycarbonyl (Ci-C8) alkyl, (C3-C8) -Cycloalkoxycarbonyl- (Ci-C8) - alkyl, (C3-C8) cycloalkyl- ( Ci-C8) alkoxycarbonyl (Ci-C 8) alkyl, (Ci-C 8) - alkylaminocarbonyl (Ci-C8) alkyl, aminocarbonyl (Ci-C8) alkyl, bis (Ci-C 8 ) -alkylaminocarbonyl- (Ci-C 8) alkyl, (C 3 -C 8) - cycloalkylaminocarbonyl (Ci-C8) alkyl, aryl (Ci-Cs) - alkylaminocarbonyl (Ci-C8) alkyl, heteroaryl - (Ci-C8) - alkylaminocarbonyl (Ci-C8) alkyl, cyano (Ci-C8) alkylaminocarbonyl (Ci-C 8) alkyl, (Ci-C 8) -Haloalkylaminocarbonyl- (Ci-C 8 ) alkyl, (C 2 -C 8) - alkynyl, (Ci-C8) alkylaminocarbonyl (Ci-C8) alkyl, (C 3 -C 8) cycloalkyl (Ci-C8) -alkylaminocarbonyl- (Ci-C 8) alkyl, (Ci-C 8) - Alkoxycarbonylaminocarbonyl- (Ci-C8) alkyl, aryl (Ci-Cs) - alkoxycarbonylaminocarbonyl- (Ci-C8) alkyl,
    (Ci-C8)-Alkoxycarbonyl-(Ci-C8)-alkylaminocarbonyl, Hydroxycarbonyl- (Ci-C8)-alkylaminocarbonyl, Aminocarbonyl-(Ci-C8)- alkylaminocarbonyl, (Ci-C8)-Alkylaminocarbonyl-(Ci-C8)- alkylaminocarbonyl, (C3-C8)-Cycloalkylaminocarbonyl-(Ci-C8)- alkylaminocarbonyl, (C3-C8)-Cycloalkyl-(Ci-C8)-alkylaminocarbonyl, (C3-C8)-Cycloalkyl-(Ci-C8)-alkylaminocarbonyl-(Ci-C 8 )-alkyl, (C 2 -C 8 )- Alkenyloxycarbonyl, (C2-C8)-Alkenyloxycarbonyl-(Ci-C8)-alkyl, (C2-C8)- Alkenylaminocarbonyl, (C2-C8)-Alkenyl-(Ci-C8)-alkylaminocarbonyl, (C2-C8)-Alkenylaminocarbonyl-(Ci-C 8 )-alkyl, (C2-C 8 )-Alkenyl-(Ci-C 8 )- alkylaminocarbonyl-(Ci-C8)-alkyl steht. (Ci-C8) -alkoxycarbonyl (Ci-C8) alkylaminocarbonyl, hydroxycarbonyl (Ci-C8) alkylaminocarbonyl, aminocarbonyl (Ci-C8) - alkylaminocarbonyl, (Ci-C8) alkylaminocarbonyl (Ci-C8) - alkylaminocarbonyl, (C3-C8) -Cycloalkylaminocarbonyl- (Ci-C8) - alkylaminocarbonyl, (C3-C8) cycloalkyl- (Ci-C8) alkylaminocarbonyl, (C3-C8) cycloalkyl- (Ci-C8) -alkylaminocarbonyl- (Ci-C8) alkyl, (C2-C8) - alkenyloxycarbonyl, (C2-C8) -Alkenyloxycarbonyl- (Ci-C8) alkyl, (C2-C8) - alkenylaminocarbonyl, (C2-C8) alkenyl - (Ci-C8) alkylaminocarbonyl, (C2-C8) -Alkenylaminocarbonyl- (Ci-C 8) alkyl, (C2-C8) alkenyl (Ci-C 8) - alkylaminocarbonyl (Ci-C8) - alkyl.
    Verwendung von Verbindungen der allgemeinen Formel (I) oder deren Salze gemäß Anspruch 1 , wobei Use of compounds of general formula (I) or salts thereof according to claim 1, wherein
    Q für die Gruppierungen Q represents the groups
    Figure imgf000302_0001
    Q-1 Q-20 Q-21 Q-1 Q-20 Q-21
    Figure imgf000302_0002
    Q-22 Q-23 Q-24 steht, und wobei die Reste R 4 bis R 8 , und R 41 bis R 84 sowie Y und m und p jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zum Schwefelatom der S0 2 -Gruppe steht; Q-22 Q-23 Q-24 is, and where the radicals R 4 to R 8 and R 41 to R 84 and Y and m and p are each as defined in accordance with the following definitions and where the arrow represents a bond to the sulfur atom the S0 2 group; A 1 , A 2 , A 3 gleich oder verschieden sind und unabhängig voneinander für N A 1, A 2, A 3 are identical or different and are each independently N
    (Stickstoff) oder die Gruppierung CW stehen, wobei jedoch in keinem Fall mehr als zwei N-Atome benachbart sind, und wobei W in der Gruppierung CW jeweils gleiche oder verschiedene Bedeutungen gemäß der nachstehenden Definition hat, (Nitrogen) or the group CW are, but in no case more than two N atoms are adjacent, and wherein W in the group CW has the same or different meanings as defined below,
    W jeweils für Wasserstoff, Nitro, Amino, Cyano, Thiocyanato, W each represent hydrogen, nitro, amino, cyano, thiocyanato,
    Isothiocyanato, Halogen, (Ci-Ce)-Alkyl, (C 3 -C 6 )-Cycloalkyl, (C 2 -C 6 )- Alkenyl, (C 2 -C 6 )-Alkinyl, Aryl, Aryl-(Ci-C 6 )-alkyl, Aryl-(Ci-C 6 )-alkoxy, Heteroaryl, (Ci-C 6 )-Alkoxy-(Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkyl, (C 3 -C 6 )- Halocycloalkyl, (Ci-C 6 )-Alkoxy, (Ci-C 6 )-Haloalkoxy, Aryloxy, Isothiocyanato, halogen, (Ci-Ce) alkyl, (C 3 -C 6) -cycloalkyl, (C 2 -C 6) - alkenyl, (C 2 -C 6) -alkynyl, aryl, aryl- (Ci-C 6) alkyl, aryl (Ci-C 6) alkoxy, heteroaryl, (Ci-C 6) alkoxy (Ci-C 6) alkyl, (Ci-C 6) -haloalkyl, (C 3 -C 6) - halocycloalkyl, (Ci-C 6) alkoxy, (Ci-C 6) haloalkoxy, aryloxy,
    Heteroaryloxy, (C3-C6)-Cycloalkyloxy, (C3-C6)-Cycloalkyl-(Ci-C6)- alkoxy, (Ci-C6)-Alkoxycarbonyl, (Ci-C6)-Alkoxycarbonyl-(Ci-C6)-alkyl, Hydroxycarbonyl, Aminocarbonyl, (Ci-C6)-Alkylaminocarbonyl, (C3-C6)- Cycloalkylaminocarbonyl, Cyano-(Ci-C6)-alkylaminocarbonyl, (C2-C6)- Alkenylaminocarbonyl, (C2-C6)-Alkinylaminocarbonyl, (C1-C6)- Heteroaryloxy, (C3-C6) -cycloalkyloxy, (C3-C6) cycloalkyl (Ci-C6) - alkoxy, (Ci-C6) -alkoxycarbonyl, (Ci-C6) -alkoxycarbonyl (Ci-C6) alkyl, hydroxycarbonyl, aminocarbonyl, (Ci-C6) alkylaminocarbonyl, (C3-C6) - cycloalkylaminocarbonyl, cyano (Ci-C6) alkylaminocarbonyl, (C2-C6) - alkenylaminocarbonyl, (C2-C6) -Alkinylaminocarbonyl, (C1-C6 ) -
    Alkylamino, (Ci-C 6 )-Alkylthio, (Ci-C 6 )-Haloalkylthio, Bis-(Ci-Ce)- alkylamino, (C3-C6)-Cycloalkylamino, (Ci-C6)-Alkylcarbonylamino, (C3-C6)-Cycloalkylcarbonylamino, Formylamino, (C1-C6)- Haloalkylcarbonylamino, (Ci-C6)-Alkoxycarbonylamino, (C1-C6)- Alkylaminocarbonylamino, Bis-[(Ci-C6)-Alkyl]-aminocarbonyl-amino, (Ci-C6)-Alkylsulfonylamino, (C3-C6)-Cycloalkylsulfonylamino, Alkylamino, (C 6) alkylthio, (Ci-C 6) haloalkylthio, bis (Ci-Ce) - alkylamino, (C3-C6) cycloalkylamino, (Ci-C6) alkylcarbonylamino, (C3-C6 ) -Cycloalkylcarbonylamino, formylamino, (C1-C6) - Haloalkylcarbonylamino, (Ci-C6) alkoxycarbonylamino, (C1-C6) - alkylaminocarbonylamino, bis - [(Ci-C6) alkyl] aminocarbonyl-amino, (Ci-C6 ) alkylsulfonylamino, (C3-C6) -Cycloalkylsulfonylamino,
    Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl-(Ci-Ce)- haloalkylamino, Amino-(Ci-C6)-alkylsulfonyl, Amino-(Ci-C6)- haloalkylsulfonyl, (Ci-C6)-Alkylsulfonyl, (C3-C6)-Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C6)-Alkylsulfinyl, (C3-C6)-Cycloalkylsulfinyl, Arylsulfinyl, N,S-Di-(Ci-C 6 )-alkylsulfonimidoyl, S-(Ci-C 6 )-Alkylsulfonimidoyl, Arylsulfonylamino, Hetarylsulfonylamino, sulfonyl (Ci-Ce) - haloalkylamino, amino (Ci-C6) alkylsulfonyl, amino (Ci-C6) - haloalkylsulfonyl, (Ci-C6) alkylsulfonyl, (C3-C6) cycloalkylsulfonyl, arylsulfonyl, (Ci-C6) alkylsulfinyl, (C3-C6) -Cycloalkylsulfinyl, arylsulfinyl, N, S-di- (Ci-C 6) -alkylsulfonimidoyl, S- (Ci-C 6) -Alkylsulfonimidoyl,
    (Ci-C6)-Alkylsulfonylaminocarbonyl, (C3-C6)- Cycloalkylsulfonylaminocarbonyl, (C3-C6)-Cycloalkylaminosulfonyl, Aryl-(Ci-C6)-alkylcarbonylamino, (C3-C6)-Cycloalkyl-(Ci-C6)- alkylcarbonylamino, Heteroarylcarbonylamino, (Ci-C6)-Alkoxy-(Ci-C6)- alkylcarbonylamino, Hydroxy-(Ci-C6)-alkylcarbonylamino steht, für H, Nitro, Amino, Cyano, Halogen, (Ci-C 6 )-Alkyl, (C 3 -C 6 )-Cycloalkyl, (C 2 -C 6 )-Alkenyl, (C 2 -C 6 )-Alkinyl, Aryl, Aryl-(Ci-C 6 )-alkyl, Heteroaryl, (Ci-C 6 )-Alkoxy-(Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkyl, (C 3 -C 6 )-Halocycloalkyl, (Ci-C 6 )-Alkoxy, (Ci-C 6 )-Haloalkoxy, (Ci-C 6 )-Alkylthio, (Ci-C 6 )- Haloalkylthio, (Ci-C6)-Alkoxycarbonyl, Hydroxycarbonyl, (Ci-C6) -Alkylsulfonylaminocarbonyl, (C3-C6) - Cycloalkylsulfonylaminocarbonyl, (C3-C6) -Cycloalkylaminosulfonyl, aryl (Ci-C6) alkylcarbonylamino, (C3-C6) cycloalkyl (Ci-C6) - alkylcarbonylamino, heteroarylcarbonylamino, (Ci-C6) alkoxy (Ci-C6) - alkylcarbonylamino, hydroxy (Ci-C6) alkylcarbonylamino, represents H, nitro, amino, cyano, halogen, (Ci-C 6) alkyl, ( C 3 -C 6) -cycloalkyl, (C 2 -C 6) -alkenyl, (C 2 -C 6) -alkynyl, aryl, aryl- (Ci-C 6) alkyl, heteroaryl, (Ci-C 6) alkoxy (Ci-C 6) alkyl, (Ci-C 6) -haloalkyl, (C 3 -C 6) halocycloalkyl, (Ci-C 6) alkoxy, (Ci-C 6) -haloalkoxy, ( Ci-C 6) alkylthio, (Ci-C 6) - haloalkylthio, (Ci-C6) alkoxycarbonyl, hydroxycarbonyl,
    Aminocarbonyl, (Ci-C6)-Alkylaminocarbonyl, (Ci-C6)-Alkylamino, Bis- (Ci-C6)-alkylamino, (C3-C6)-Cycloalkylamino, (C1-C6)- Alkylcarbonylamino, (C3-C6)-Cycloalkylcarbonylamino, Formylamino, (Ci-C6)-Haloalkylcarbonylamino, (Ci-C6)-Alkoxycarbonylamino, Aminocarbonyl, (Ci-C6) alkylaminocarbonyl, (Ci-C6) alkylamino, bis (Ci-C6) alkylamino, (C3-C6) cycloalkylamino, (C1-C6) - alkylcarbonylamino, (C3-C6) - cycloalkylcarbonylamino, formylamino, (Ci-C6) -Haloalkylcarbonylamino, (Ci-C6) alkoxycarbonylamino,
    [(Ci-C6)-Alkyl-]aminocarbonyl-amino, Sulfonylamino, (C1-C6)- Alkylsulfonylamino, (Ci-C6)-Haloalkylsulfonylamino, (C3-C6)- Cycloalkylsulfonylamino, Amino-(Ci-C6)-alkylsulfonyl, Amino-(Ci-C6)- haloalkylsulfonyl, (Ci-C6)-Alkylsulfonyl, (C3-C6)-Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C6)-Alkylsulfinyl, (C3-C6)-Cycloalkylsulfinyl, Arylsulfinyl, N,S-Di-(Ci-C 6 )-alkylsulfonimidoyl, S-(Ci-C 6 )-Alkylsulfonimidoyl, [(Ci-C6) alkyl] aminocarbonyl-amino, sulfonylamino, (C1-C6) - alkylsulfonylamino, (Ci-C6) -Haloalkylsulfonylamino, (C3-C6) - cycloalkylsulfonylamino, amino (Ci-C6) alkylsulfonyl, amino (Ci-C6) - haloalkylsulfonyl, (Ci-C6) alkylsulfonyl, (C3-C6) cycloalkylsulfonyl, arylsulphonyl, (Ci-C6) alkylsulfinyl, (C3-C6) -Cycloalkylsulfinyl, arylsulfinyl, N, S di- (Ci-C 6) -alkylsulfonimidoyl, S- (Ci-C 6) -Alkylsulfonimidoyl,
    (Ci-C6)-Alkylsulfonylaminocarbonyl, (C3-C6)- Cycloalkylsulfonylaminocarbonyl, (C3-C6)-Cycloalkylaminosulfonyl, Amino-(Ci-C6)-alkyl, Amino-(C2-C6)-alkenyl, (C2-C6)-Alkenylamino, (C2- C6)-Alkenylimino steht, (Ci-C6) -Alkylsulfonylaminocarbonyl, (C3-C6) - Cycloalkylsulfonylaminocarbonyl, (C3-C6) -Cycloalkylaminosulfonyl, amino (Ci-C6) alkyl, amino (C2-C6) -alkenyl, (C2-C6) - alkenylamino, (C2- C6) -Alkenylimino stands,
    R 2 für H, Nitro, Amino, Cyano, Halogen, (Ci-Ce)-Alkyl, (C 3 -C 6 )-Cycloalkyl, R 2 is H, nitro, amino, cyano, halogen, (Ci-Ce) alkyl, (C 3 -C 6) -cycloalkyl,
    (C 2 -C 6 )-Alkenyl, (C 2 -C 6 )-Alkinyl, Aryl, Aryl-(Ci-C 6 )-alkyl, Heteroaryl, (Ci-C 6 )-Alkoxy-(Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkyl, (C 3 -C 6 )-Halocycloalkyl, (Ci-C 6 )-Alkoxy, (Ci-C 6 )-Haloalkoxy, (Ci-C 6 )-Alkylthio, (Ci-C 6 )- Haloalkylthio, (Ci-C6)-Alkoxycarbonyl, Hydroxycarbonyl, (C 2 -C 6) -alkenyl, (C 2 -C 6) -alkynyl, aryl, aryl- (Ci-C 6) alkyl, heteroaryl, (Ci-C 6) alkoxy (Ci-C 6) alkyl, (Ci-C 6) -haloalkyl, (C 3 -C 6) halocycloalkyl, (Ci-C 6) alkoxy, (Ci-C 6) haloalkoxy, (Ci-C 6) -alkylthio, ( Ci-C 6) - haloalkylthio, (Ci-C6) alkoxycarbonyl, hydroxycarbonyl,
    Aminocarbonyl, (Ci-C6)-Alkylaminocarbonyl, (Ci-C6)-Alkylamino, Bis- (Ci-C6)-alkylamino, (C3-C6)-Cycloalkylamino, (C1-C6)- Alkylcarbonylamino, (C3-C6)-Cycloalkylcarbonylamino, Formylamino, (Ci-C6)-Haloalkylcarbonylamino, (Ci-C6)-Alkoxycarbonylamino, Aminocarbonyl, (Ci-C6) alkylaminocarbonyl, (Ci-C6) alkylamino, bis (Ci-C6) alkylamino, (C3-C6) cycloalkylamino, (C1-C6) - alkylcarbonylamino, (C3-C6) - cycloalkylcarbonylamino, formylamino, (Ci-C6) -Haloalkylcarbonylamino, (Ci-C6) alkoxycarbonylamino,
    [(Ci-C6)-Alkyl-]-aminocarbonyl-amino, Sulfonylamino, (C1-C6)- Alkylsulfonylamino, (Ci-C6)-Haloalkylsulfonylamino, (C3-C6)- Cycloalkylsulfonylamino, Amino-(Ci-C6)-alkylsulfonyl, Amino-(Ci-C6)- haloalkylsulfonyl, (Ci-C6)-Alkylsulfonyl, (C3-C6)-Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C6)-Alkylsulfinyl, (C3-C6)-Cycloalkylsulfinyl, Arylsulfinyl, N,S-Di-(Ci-C 6 )-alkylsulfonimidoyl, S-(Ci-C 6 )-Alkylsulfonimidoyl, [(Ci-C6) alkyl -] - aminocarbonyl-amino, sulfonylamino, (C1-C6) - alkylsulfonylamino, (Ci-C6) -Haloalkylsulfonylamino, (C3-C6) - cycloalkylsulfonylamino, amino (Ci-C6) alkylsulfonyl , amino (Ci-C6) - haloalkylsulfonyl, (Ci-C6) alkylsulfonyl, (C3-C6) cycloalkylsulfonyl, arylsulphonyl, (Ci-C6) alkylsulfinyl, (C3-C6) -Cycloalkylsulfinyl, arylsulfinyl, N, S di- (Ci-C 6) -alkylsulfonimidoyl, S- (Ci-C 6) -Alkylsulfonimidoyl,
    (Ci-C6)-Alkylsulfonylaminocarbonyl, (C3-C6)- Cycloalkylsulfonylaminocarbonyl, (C3-C6)-Cycloalkylaminosulfonyl, Amino-(Ci-C6)-alkyl, Amino-(C2-C6)-alkenyl, (C2-C6)-Alkenylamino, (C2- C6)-Alkenylimino steht, (Ci-C6) -Alkylsulfonylaminocarbonyl, (C3-C6) - Cycloalkylsulfonylaminocarbonyl, (C3-C6) -Cycloalkylaminosulfonyl, amino (Ci-C6) alkyl, amino (C2-C6) -alkenyl, (C2-C6) - alkenylamino, (C2- C6) -Alkenylimino stands,
    R 1 und R 2 mit den Atomen, an die sie gebunden sind, einen vollständig R 1 and R 2 with the atoms to which they are attached form a fully
    gesättigten, teilgesättigten oder vollständig ungesättigten, saturated, partially saturated or fully unsaturated,
    gegebenenfalls durch Heteroatome unterbrochenen und optionally interrupted by hetero atoms and
    gegebenenfalls weiter durch W substituierten 5 bis 7-gliedrigen Ring bilden, und wobei sie im Falle der Verbindungen der allgemeinen Formel (I) mit den Gruppierungen Q-21 und Q-23 einen optionally further form to 7-membered ring substituted by W 5, and wherein a in the case of compounds of general formula (I) with the moieties Q-21 and Q-23
    entsprechenden Ring bilden müssen. must make appropriate ring. R 1 und A 3 , wenn A 3 für eine Gruppe CW steht, mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten, teilgesättigten oder vollständig ungesättigten, gegebenenfalls durch Heteroatome unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7- gliedrigen Ring bilden, R 1 and A 3, when A 3 is a group CW, with the atoms to which they are attached form a fully saturated, partially saturated or fully unsaturated, optionally interrupted by hetero atoms and optionally further substituted 5 form to 7-membered ring,
    X für eine direkte Bindung oder für eine Gruppierung (CHR 3 ) n steht, und wobei R 3 in der Gruppierung (CHR 3 ) n jeweils gleiche oder X is a direct bond or a group (CHR 3) n and wherein R 3 in the group (CHR 3) n, the same or
    verschiedene Bedeutungen gemäß der nachstehenden Definition hat, n für 0, 1 steht für H, (Ci-Ce)-Alkyl, (C 2 -Ce)-Alkenyl-(Ci-Ce)-alkyl, (Ci-C 6 )-Haloalkyl, (C 3 -C 6 )-Cycloalkyl, (C3-C 6 )-Cycloalkyl-(Ci-C 6 )-alkyl, Aryl-(Ci-C 6 )-alkyl, Heteroaryl-(Ci-C 6 )-alkyl, (Ci-C 6 )-Alkoxy-(Ci-C 6 )-alkyl, (Ci-C 6 )- Haloalkoxy-(Ci-C 6 )-alkyl, (Ci-C 6 )-Alkylthio-(Ci-C 6 )-alkyl, (Ci-C 6 )- Haloalkylthio-(Ci-C 6 )-alkyl steht, für H, (Ci-C 6 )-Alkyl, (C2-C 6 )-Alkenyl-(Ci-C 6 )-alkyl, (C 2 -C 6 )-Alkinyl, different meanings defined below has, n is 0, 1 represents H, (Ci-Ce) alkyl, (C2 -Ce) alkenyl (Ci-Ce) alkyl, (Ci-C 6) -haloalkyl , (C 3 -C 6) -cycloalkyl, (C3-C6) cycloalkyl (Ci-C 6) alkyl, aryl (Ci-C 6) alkyl, heteroaryl (Ci-C 6) alkyl , (Ci-C 6) alkoxy (Ci-C 6) alkyl, (Ci-C 6) - haloalkoxy (Ci-C 6) alkyl, (Ci-C 6) alkylthio (Ci-C 6) alkyl, (Ci-C 6) - Haloalkylthio- (Ci-C 6) alkyl, H, (Ci-C 6) -alkyl, (C2-C6) alkenyl (Ci-C 6 ) alkyl, (C 2 -C 6) alkynyl,
    (Ci-C6)-Alkylcarbonyl, (C3-C6)-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl, (Ci-C6)-Alkoxycarbonyl, Aryl-(Ci-Ce)- alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl- (Ci-C 6 )-alkoxycarbonyl, (Ci-C 6 )-Alkylsulfonyl, (C 3 -C 6 )- Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C6)-Alkoxycarbonylcarbonyl, Aryl- (Ci-C6)-alkoxycarbonylcarbonyl, (Ci-C6)-Alkylaminothiocarbonyl, (Ci-C6) alkylcarbonyl, (C3-C6) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl, (Ci-C6) alkoxycarbonyl, aryl (Ci-Ce) - alkoxycarbonyl, (C3-C6) cycloalkoxycarbonyl, (C3-C6 ) cycloalkyl (Ci-C 6) -alkoxycarbonyl, (Ci-C 6) alkylsulfonyl, (C 3 -C 6) - cycloalkylsulfonyl, arylsulfonyl, (Ci-C6) -Alkoxycarbonylcarbonyl, aryl (Ci-C6) - alkoxycarbonylcarbonyl, (Ci-C6) -Alkylaminothiocarbonyl,
    (Ci-C6)-Alkylaminocarbonyl, Aryl-(Ci-C6)-alkyl, Hetaroaryl-(Ci-C6)-alkyl, Cyano-(Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkyl, (C 3 -C 6 )-Cycloalkyl, (C 3 -C 6 )- Cycloalkyl-(Ci-C 6 )-alkyl, (Ci-C 6 )-Alkoxy-(Ci-C 6 )-alkyl, (Ci-C 6 )- Haloalkoxy-(Ci-C 6 )-alkyl, (C2-C 6 )-Alkinyl-(Ci-C 6 )-alkyl, (Ci-C 6 )- Alkoxycarbonyl-(Ci-C6)-alkyl, Aminocarbonyl-(Ci-C6)-alkyl, (C1-C6)- Alkylaminocarbonyl-(Ci-C6)-alkyl, Bis-(Ci-C6)-alkylaminocarbonyl- (Ci-C 6 )-alkyl steht, für Halogen, (C2-C6)-Alkyl, (Ci-C6)-Alkoxy, (Ci-C6)-Alkoxycarbonyloxy, (C 2 -C 6 )-Alkenyl, (C 2 -C 6 )-Haloalkenyl, (C2-C 6 )-Alkenyl-(Ci-C 6 )-alkyl, (C 2 -C 6 )-Alkinyl, (C2-C 6 )-Alkinyl-(Ci-C 6 )-alkyl, Aryl-(Ci-C 6 )-alkyl, Bisaryl- (Ci-C 6 )-alkyl, Aryl-(Ci-C 6 )-alkoxyaryl-(Ci-C 6 )-alkyl, Aryloxyaryl-(Ci-C 6 )- alkyl, (Ci-C 6 )-Alkoxyaryl-(Ci-C 6 )-alkyl, Heteroaryl-(Ci-C 6 )-alkyl, (Ci-C6) alkylaminocarbonyl, aryl (Ci-C6) alkyl, Hetaroaryl- (Ci-C6) alkyl, cyano (Ci-C 6) alkyl, (Ci-C 6) -haloalkyl, (C 3 -C 6) -cycloalkyl, (C 3 -C 6) - cycloalkyl, (Ci-C 6) alkyl, (Ci-C 6) alkoxy (Ci-C 6) alkyl, (Ci-C 6 ) - haloalkoxy (Ci-C 6) alkyl, (C2-C6) alkynyl (Ci-C 6) alkyl, (Ci-C 6) - alkoxycarbonyl (Ci-C6) alkyl, aminocarbonyl (Ci-C6) alkyl, (C1-C6) - alkylaminocarbonyl (Ci-C6) alkyl, bis (Ci-C6) alkylaminocarbonyl (Ci-C 6) alkyl, halo, (C2 C6) alkyl, (Ci-C6) -alkoxy, (Ci-C6) alkoxycarbonyloxy, (C2-C6) -alkenyl, (C2-C6) haloalkenyl, (C2-C6) -alkenyl (Ci-C 6) alkyl, (C 2 -C 6) -alkynyl, (C2-C6) alkynyl (Ci-C 6) alkyl, aryl (Ci-C 6) alkyl, bisaryl (Ci-C 6) alkyl, aryl (Ci-C 6) -alkoxyaryl- (Ci-C 6) alkyl, Aryloxyaryl- (Ci-C 6) - alkyl, (Ci-C 6) -Alkoxyaryl- ( Ci-C 6) alkyl, heteroaryl (Ci-C 6) alkyl,
    Heterocyclyl-(Ci-C 6 )-alkyl, N-(Ci-C 6 )-Alkylheterocyclyl-(Ci-C 6 )-alkyl, N- [(Ci-C 6 )-Alkoxycarbonyl]heterocyclyl-(Ci-C 6 )-alkyl, N-(Aryl-(Ci-C 6 )- alkoxycarbonyl)heterocyclyl-(Ci-C6)-alkyl, N-(Arylcarbonyl)heterocyclyl- (Ci-C 6 )-alkyl, N-[(Ci-C 6 )-Alkylcarbonyl]heterocyclyl-(Ci-C 6 )-alkyl, N- [(C3-C6)-Cycloalkylcarbonyl]heterocyclyl-(Ci-C6)-alkyl, Cyano-(Ci-C6)- alkyl, (Ci-C 6 )-Haloalkyl, (C 3 -C 6 )-Cycloalkyl, (C 3 -C 6 )-Halocycloalkyl, (C 4 -C 6 )-Cycloalkenyl, (C3-C6)-Cycloalkyl-(Ci-C 6 )-alkyl, (C 3 -C 6 )- Cycloalkenyl-(Ci-C 6 )-alkyl, Hydroxy-(Ci-C 6 )-alkyl, (Ci-C 6 )-Alkoxy- (Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkoxy-(Ci-C 6 )-alkyl, Aryloxy-(Ci-C 6 )-alkyl, Aryl-(Ci-C 6 )-alkoxy-(Ci-C 6 )-alkyl, Heteroaryl-(Ci-C 6 )-alkoxy-(Ci-C 6 )- alkyl, (C3-C 6 )-Cycloalkoxy-(Ci-C 6 )-alkyl, (C3-C 6 )-Cycloalkyl-(Ci-C 6 )- alkoxy-(Ci-C 6 )-alkyl, (Ci-C 6 )-Alkylcarbonyloxy-(Ci-C 6 )-alkyl, Heterocyclyl (Ci-C 6) alkyl, N- (Ci-C 6) -Alkylheterocyclyl- (Ci-C 6) alkyl, N [(Ci-C 6) alkoxycarbonyl] heterocyclyl (Ci-C 6 ) alkyl, N- (aryl (Ci-C 6) - alkoxycarbonyl) heterocyclyl (Ci-C6) alkyl, N- (arylcarbonyl) heterocyclyl- (Ci-C 6) -alkyl, N - [(Ci- C6) alkyl-carbonyl] heterocyclyl (Ci-C 6) alkyl, N- [(C3-C6) cycloalkylcarbonyl] heterocyclyl (Ci-C6) alkyl, cyano (Ci-C6) - alkyl, (Ci -C 6) -haloalkyl, (C 3 -C 6) -cycloalkyl, (C 3 -C 6) halocycloalkyl, (C 4 -C 6) -cycloalkenyl, (C3-C6) cycloalkyl (Ci-C 6 ) alkyl, (C 3 -C 6) - cycloalkenyl, (Ci-C 6) alkyl, hydroxy (Ci-C 6) alkyl, (Ci-C 6) alkoxy (Ci-C 6) - alkyl, (Ci-C 6) haloalkoxy (Ci-C 6) alkyl, aryloxy (Ci-C 6) alkyl, aryl (Ci-C 6) alkoxy (Ci-C 6) alkyl , heteroaryl (Ci-C 6) alkoxy (Ci-C 6) - alkyl, (C3-C6) cycloalkoxy (Ci-C 6) alkyl, (C3-C6) cycloalkyl (Ci -C6) - alkoxy- (Ci-C 6) alkyl, (Ci-C 6) alkylcarbonyloxy (Ci-C 6) alkyl,
    Arylcarbonyloxy-(Ci-C6)-alkyl, Heteroarylcarbonyloxy-(Ci-C6)-alkyl, (C3-C6)-Cycloalkylcarbonyloxy-(Ci-C6)-alkyl, Arylsulfonyloxy-(Ci-C6)- alkyl, (Ci-C 6 )-Alkylsulfonyloxy-(Ci-C 6 )-alkyl, Hydrothio-(Ci-C 6 )-alkyl, (Ci-C 6 )-Alkylthio-(Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkylthio-(Ci-C 6 )-alkyl, Aryl- (Ci-C 6 )-alkylthio-(Ci-C 6 )-alkyl, (C3-C 6 )-Cycloalkylthio-(Ci-C 6 )-alkyl, Arylthio-(Ci-C 6 )-alkyl, (Ci-C 6 )-Alkylsulfinyl-(Ci-C 6 )-alkyl, (Ci-C 6 )- Alkylsulfonyl-(Ci-C 8 )-alkyl, (Ci-C 6 )-Haloalkylsulfinyl-(Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkylsulfonyl-(Ci-C 6 )-alkyl, Aryl-(Ci-C 6 )-alkylsulfinyl- (Ci-C 6 )-alkyl, Aryl-(Ci-C 6 )-alkylsulfonyl-(Ci-C 6 )-alkyl, (C 3 -C 6 )- Cycloalkylsulfinyl-(Ci-C 6 )-alkyl, (C3-C6)-Cycloalkylsulfonyl-(Ci-C 6 )-alkyl, Aryl, Heteroaryl, Heterocyclyl, N-[(Ci-C 6 )-Alkyl]heterocyclyl, N-[(Ci-C 6 )- Alkoxycarbonyl]heterocyclyl, N-[Aryl-(Ci-C6)- alkoxycarbonyl]heterocyclyl, N-(Arylcarbonyl)heterocyclyl, N-[(Ci-C6)- Alkylcarbonyl]heterocyclyl, N-[(Ci-C6)-Cycloalkylcarbonyl]heterocyclyl, Hydroxycarbonyl, (Ci-C6)-Alkoxycarbonyl, (C3-C6)- Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkoxycarbonyl, Aryl- (Ci-C6)-alkoxycarbonyl, Heteroaryl-(Ci-C6)-alkoxycarbonyl, (C1-C6)- Alkylaminocarbonyl, Aminocarbonyl, Bis-(Ci-C6)-alkylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Aryl-(Ci-C6)-alkylaminocarbonyl, Heteroarylaminocarbonyl, Cyano-(Ci-C6)-alkylaminocarbonyl, (C1-C6)- Haloalkylaminocarbonyl, (C2-C6)-Alkinyl-(Ci-C6)-alkylaminocarbonyl, Hydroxycarbonyl-(Ci-C6)-alkyl, (Ci-C6)-Alkoxycarbonyl-(Ci-C6)-alkyl, (C3-Ce)-Cycloalkox carbonyl-(Ci-Ce)-alkyl, (C3-C 6 )-Cycloalkyl-(Ci-C 6 )- alkoxycarbonyl-(Ci-C6)-alkyl, Aryl-(Ci-C6)-alkoxycarbonyl-(Ci-C6)-alkyl, Heteroaryl-(Ci-C6)-alkoxycarbonyl-(Ci-C6)-alkyl, (C1-C6)- Alkylaminocarbonyl-(Ci-C6)-alkyl, Aminocarbonyl-(Ci-C6)-alkyl, Bis- (Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, (C3-C6)- Cycloalkylaminocarbonyl-(Ci-C6)-alkyl, Aryl-(Ci-Ce)- alkylaminocarbonyl-(Ci-C6)-alkyl, Heteroarylaminocarbonyl-(Ci-C6)- alkyl, Cyano-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, (Ci-Ce)- Haloalkylaminocarbonyl-(Ci-C 6 )-alkyl, (C2-C 8 )-Alkinyl-(Ci-C 8 )- alkylaminocarbonyl-(Ci-C8)-alkyl, Amino-(Ci-C6)-alkyl, (Ci-Ce)- Alkylamino-(Ci-C 6 )-alkyl, (C2-C 6 )-Alkenylamino-(Ci-C 6 )-alkyl, Arylcarbonyloxy (Ci-C6) alkyl, Heteroarylcarbonyloxy- (Ci-C6) alkyl, (C3-C6) -Cycloalkylcarbonyloxy- (Ci-C6) alkyl, arylsulfonyloxy (Ci-C6) - alkyl, (Ci-C 6) alkylsulfonyloxy (Ci-C 6) alkyl, Hydrothio- (Ci-C 6) alkyl, (Ci-C 6) alkylthio (Ci-C 6) alkyl, (Ci-C 6) - Haloalkylthio- (Ci-C 6) alkyl, aryl (Ci-C 6) alkylthio (Ci-C 6) alkyl, (C3-C6) cycloalkylthio (Ci-C 6) alkyl, arylthio - (Ci-C 6) alkyl, (Ci-C 6) alkylsulfinyl (Ci-C 6) alkyl, (Ci-C 6) - alkylsulfonyl (Ci-C 8) alkyl, (Ci-C 6) -Haloalkylsulfinyl- (Ci-C 6) alkyl, (Ci-C 6) -Haloalkylsulfonyl- (Ci-C 6) alkyl, aryl (Ci-C 6) alkylsulfinyl (Ci-C 6) - alkyl, aryl (Ci-C 6) alkylsulfonyl (Ci-C 6) alkyl, (C 3 -C 6) - Cycloalkylsulfinyl- (Ci-C 6) alkyl, (C3-C6) -Cycloalkylsulfonyl- ( Ci-C 6) alkyl, aryl, heteroaryl, heterocyclyl, N - [(Ci-C 6) -alkyl] heterocyclyl, N - [(Ci-C 6) - alkoxycarbonyl] heterocyclyl, N- [aryl- (Ci- C6) - alkoxycarbonyl] heterocyclyl, N- (arylcarbonyl) heterocyclyl, N - [(Ci-C6) - alkyl carbonyl] heterocyclyl, N - [(Ci-C6) cycloalkylcarbonyl] heterocyclyl, hydroxycarbonyl, (Ci-C6) -alkoxycarbonyl, (C3-C6) - cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C6) alkoxycarbonyl, aryl (Ci-C6) alkoxycarbonyl, heteroaryl (Ci-C6) -alkoxycarbonyl, (C1-C6) - alkylaminocarbonyl, aminocarbonyl, bis (Ci-C6) alkylaminocarbonyl, (C3-C6) cycloalkylaminocarbonyl, aryl (Ci-C6) alkylaminocarbonyl, heteroarylaminocarbonyl, cyano (Ci-C6) alkylaminocarbonyl, (C1-C6) - Haloalkylaminocarbonyl, (C2-C6) alkynyl (Ci-C6) alkylaminocarbonyl, hydroxycarbonyl (Ci-C6) alkyl, (Ci-C6) -alkoxycarbonyl (Ci-C6) alkyl, (C3-Ce) - Cycloalkox carbonyl (C-Ce) alkyl, (C3-C6) cycloalkyl (C 6) - alkoxycarbonyl (Ci-C6) alkyl, aryl (Ci-C6) -alkoxycarbonyl (Ci C6) alkyl, heteroaryl (Ci-C6) -alkoxycarbonyl (Ci-C6) alkyl, (C1-C6) - alkylaminocarbonyl (Ci-C6) alkyl, aminocarbonyl (Ci-C6) alkyl, Up - (Ci-C6) alkylaminocarbonyl (Ci-C6) alkyl, (C3-C6) - cycloalkylaminocarbonyl (Ci-C6) alkyl, aryl (Ci-Ce) - alkylaminocarbonyl (Ci-C6) alkyl , Heteroarylaminocarbonyl- (Ci-C6) - alkyl, cyano- (Ci-C6) alkylaminocarbonyl (Ci-C6) alkyl, (Ci-Ce) - Haloalkylaminocarbonyl- (Ci-C 6) alkyl, (C2-C 8) alkynyl (Ci-C 8) - alkylaminocarbonyl (Ci-C8) alkyl, amino (Ci-C6) alkyl, (Ci-Ce) - alkylamino (Ci-C 6) alkyl, ( C2-C 6) -Alkenylamino- (Ci-C 6) alkyl,
    Arylamino-(Ci-C6)-alkyl, Bis-(Ci-C6)-alkylamino-(Ci-C6)-alkyl, Bis- (C3-C6)-cycloalkylamino-(Ci-C6)-alkyl, Aryl-(Ci-C6)-alkylamino-(Ci-C6)- alkyl, Tris-Aryl-(Ci-Ce)-alkylamino-(Ci-Ce)-alkyl, (C 3 -C 6 )- Cycloalkylamino-(Ci-C6)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkylamino- (Ci-Ce)-alkyl, (Ci-C 6 )-Haloalkylamino-(Ci-C 6 )-alkyl, (Ci-C 6 )- Alkylcarbonylamino-(Ci-C6)-alkyl, (Ci-C6)-Cycloalkylcarbonylamino- (Ci-C6)-alkyl, Arylcarbonylamino-(Ci-C6)-alkyl, Arylamino (Ci-C6) alkyl, bis (Ci-C6) alkylamino (Ci-C6) alkyl, bis (C3-C6) cycloalkylamino (Ci-C6) alkyl, aryl (Ci -C6) alkylamino (Ci-C6) - alkyl, Tris-aryl (Ci-Ce) alkylamino (Ci-Ce) alkyl, (C 3 -C 6) - cycloalkylamino (Ci-C6) - alkyl, (C3-C6) cycloalkyl (Ci-C6) alkylamino (Ci-Ce) alkyl, (Ci-C 6) -Haloalkylamino- (Ci-C 6) alkyl, (Ci-C 6) - alkylcarbonylamino (Ci-C6) alkyl, (Ci-C6) -Cycloalkylcarbonylamino- (Ci-C6) alkyl, arylcarbonylamino (Ci-C6) alkyl,
    Heteroarylcarbonylamino-(Ci-C6)-alkyl, (Ci-C6)-Alkoxycarbonylamino- (Ci-C6)-alkyl, (C2-C6)-Alkenyloxycarbonylamino-(Ci-C6)-alkyl, Aryl- (Ci-C6)-alkoxycarbonylamino-(Ci-C6)-alkyl, Aryl-(Ci-Ce)- alkoxycarbonyl[N-(Ci-C6)-alkyl]amino-(Ci-C6)-alkyl, Heteroaryl-(Ci-C6)- alkoxycarbonylamino-(Ci-C6)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C6)- alkoxycarbonylamino-(Ci-C6)-alkyl, (C3-C6)-Cycloalkoxycarbonylamino- (Ci-C6)-alkyl, Aminocarbonylamino-(Ci-C6)-alkyl, Arylsulfonylamino- (Ci-C6)-alkyl, Heteroarylsulfonylamino-(Ci-C6)-alkyl, (C1-C6)- Alkylsulfonylamino-(Ci-C6)-alkyl, (C 3 -C6)-Cycloalkylsulfonylamino- (Ci-C6)-alkyl, Aminoiminoamino-(Ci-C6)-alkyl, Heteroarylcarbonylamino- (Ci-C6) alkyl, (Ci-C6) alkoxycarbonylamino (Ci-C6) alkyl, (C2-C6) -Alkenyloxycarbonylamino- (Ci-C6) alkyl, aryl (Ci-C6) - alkoxycarbonylamino (Ci-C6) alkyl, aryl (Ci-Ce) - alkoxycarbonyl [N- (Ci-C6) alkyl] amino (Ci-C6) alkyl, heteroaryl (Ci-C6) - alkoxycarbonylamino (Ci-C6) alkyl, (C3-C6) cycloalkyl (Ci-C6) - alkoxycarbonylamino (Ci-C6) alkyl, (C3-C6) -Cycloalkoxycarbonylamino- (Ci-C6) alkyl, aminocarbonylamino (Ci-C6) alkyl, arylsulfonylamino (Ci-C6) alkyl, Heteroarylsulfonylamino- (Ci-C6) alkyl, (C1-C6) - alkylsulfonylamino (Ci-C6) alkyl, (C3-C6) -Cycloalkylsulfonylamino- (Ci-C6) alkyl, Aminoiminoamino- (Ci-C6) alkyl,
    Arylsulfonylaminoiminoamino-(Ci-C6)-alkyl, (C1-C6)- Arylsulfonylaminoiminoamino- (Ci-C6) alkyl, (C1-C6) -
    Alkylaminoiminoamino-(Ci-C6)-alkyl steht, für Wasserstoff, Halogen, (Ci-Ce)-Alkyl, (Ci-C 6 )-Alkoxy, (Ci-C 6 )- Alkoxycarbonyloxy, (C2-C6)-Alkenyl, (C2-C6)-Haloalkenyl, (C2-C6)- Alkenyl-(Ci-C 6 )-alkyl, (C 2 -C 6 )-Alkinyl, (C2-C 6 )-Alkinyl-(Ci-C 6 )-alkyl, Aryl- Alkylaminoiminoamino- (Ci-C6) alkyl, represents hydrogen, halogen, (Ci-Ce) alkyl, (Ci-C 6) alkoxy, (Ci-C 6) - alkoxycarbonyloxy, (C2-C6) alkenyl, (C2-C6) haloalkenyl, (C2-C6) - alkenyl (C 6) alkyl, (C2-C6) -alkynyl, (C2-C6) alkynyl (Ci-C6) alkyl, aryl
    (Ci-Ce)-alkyl, Bisaryl-(Ci -Ce)-alkyl , Aryl-(Ci-C 6 )-alkoxyaryl-(Ci-C 6 )- alkyl, Aryloxyaryl-(Ci-C 6 )-alkyl, (Ci-C 6 )-Alkoxyaryl-(Ci-C 6 )-alkyl, Heteroaryl-(Ci-C 6 )-alkyl, Heterocyclyl-(Ci-C 6 )-alkyl, N-(Ci-C 6 )- Alkylheterocyclyl-(Ci-C6)-alkyl, N-[(Ci-C6)-Alkoxycarbonyl]heterocyclyl- (Ci-C 6 )-alkyl, N-(Aryl-(Ci-C 6 )-alkoxycarbonyl)heterocyclyl-(Ci-C 6 )-alkyl, (Ci-Ce) alkyl, bisaryl (Ci -Ce) alkyl, aryl (Ci-C 6) -alkoxyaryl- (Ci-C 6) - alkyl, Aryloxyaryl- (Ci-C 6) alkyl, ( Ci-C 6) -Alkoxyaryl- (Ci-C 6) alkyl, heteroaryl (Ci-C 6) alkyl, heterocyclyl (Ci-C 6) alkyl, N- (Ci-C 6) - Alkylheterocyclyl- (Ci-C6) -alkyl, N - [(Ci-C6) alkoxycarbonyl] heterocyclyl (Ci-C 6) alkyl, N- (aryl (Ci-C 6) -alkoxycarbonyl) heterocyclyl- (Ci-C 6) alkyl,
    N-(Arylcarbonyl)heterocyclyl-(Ci-C 6 )-alkyl, N-[(Ci-C 6 )- Alkylcarbonyl]heterocyclyl-(Ci-C 6 )-alkyl, N-[(C 3 -C 6 )- Cycloalkylcarbonyl]heterocyclyl-(Ci-C6)-alkyl, Cyano-(Ci-C6)-alkyl, (Ci-C 6 )-Haloalkyl, (C 3 -C 6 )-Cycloalkyl, (C 3 -C 6 )-Halocycloalkyl, (C 4 -C 6 )- Cycloalkenyl, (C3-C 6 )-Cycloalkyl-(Ci-C 6 )-alkyl, (C 3 -C 6 )-Cycloalkenyl- N- (arylcarbonyl) heterocyclyl- (Ci-C 6) -alkyl, N - [(Ci-C 6) - alkylcarbonyl] heterocyclyl (Ci-C 6) -alkyl, N - [(C 3 -C 6) - cycloalkylcarbonyl] heterocyclyl (Ci-C6) -alkyl, cyano- (Ci-C6) alkyl, (Ci-C 6) -haloalkyl, (C 3 -C 6) -cycloalkyl, (C 3 -C 6) halocycloalkyl , (C 4 -C 6) - cycloalkenyl, (C3-C6) cycloalkyl (Ci-C 6) alkyl, (C 3 -C 6) cycloalkenyl
    (Ci-C 6 )-alkyl, Hydroxy-(Ci-C 6 )-alkyl, (Ci-C 6 )-Alkoxy-(Ci-C 6 )-alkyl, (Ci-C 6) alkyl, hydroxy (Ci-C 6) alkyl, (Ci-C 6) alkoxy (Ci-C 6) alkyl,
    (Ci-C 6 )-Haloalkoxy-(Ci-C 6 )-alkyl, Aryloxy-(Ci-C 6 )-alkyl, Aryl-(Ci-C 6 )- alkoxy-(Ci-C 6 )-alkyl, Heteroaryl-(Ci-C 6 )-alkoxy-(Ci-C 6 )-alkyl, (C 3 -C 6 )- Cycloalkoxy-(Ci-C 6 )-alkyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C6)-alkoxy-(Ci-C 6 )- alkyl, (Ci-C6)-Alkylcarbonyloxy-(Ci-C6)-alkyl, Arylcarbonyloxy-(Ci-C6)- alkyl, Heteroarylcarbonyloxy-(Ci-C6)-alkyl, (C 3 -C6)- Cycloalkylcarbonyloxy-(Ci-C8)-alkyl, Arylsulfonyloxy-(Ci-C6)-alkyl, (Ci-C 6 )-Alkylsulfonyloxy-(Ci-C 6 )-alkyl, Hydrothio-(Ci-C 6 )-alkyl, (Ci-C 6 )- Alkylthio-(Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkylthio-(Ci-C 6 )-alkyl, Aryl-(Ci-C 6 )- alkylthio-(Ci-C 6 )-alkyl, (C 3 -C 6 )-Cycloalkylthio-(Ci-C 6 )-alkyl, Arylthio- (Ci-C 6) haloalkoxy (Ci-C 6) alkyl, aryloxy (Ci-C 6) alkyl, aryl (Ci-C6) - alkoxy- (Ci-C 6) alkyl, heteroaryl - (Ci-C 6) alkoxy (Ci-C 6) alkyl, (C 3 -C 6) - cycloalkoxy (Ci-C 6) alkyl, (C 3 -C 6) cycloalkyl (C C6) alkoxy (Ci-C 6) - alkyl, (Ci-C6) alkylcarbonyloxy (Ci-C6) alkyl, arylcarbonyloxy (Ci-C6) - alkyl, Heteroarylcarbonyloxy- (Ci-C6) alkyl , (C 3 -C 6) - Cycloalkylcarbonyloxy- (Ci-C8) alkyl, arylsulfonyloxy (Ci-C6) alkyl, (Ci-C 6) alkylsulfonyloxy (Ci-C 6) alkyl, Hydrothio- (Ci -C 6) alkyl, (Ci-C 6) - alkylthio, (Ci-C 6) alkyl, (Ci-C 6) -Haloalkylthio- (Ci-C 6) alkyl, aryl (Ci-C 6 ) - alkylthio- (Ci-C 6) alkyl, (C 3 -C 6) cycloalkylthio (Ci-C 6) alkyl, arylthio
    (Ci-C 6 )-alkyl, (Ci-C 6 )-Alkylsulfinyl-(Ci-C 6 )-alkyl, (Ci-C 6 )-Alkylsulfonyl- (Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkylsulfinyl-(Ci-C 6 )-alkyl, (Ci-C 6 )- Haloalkylsulfonyl-(Ci-C 6 )-alkyl, Aryl-(Ci-Ce)-alkylsulfinyl-(Ci-Ce)-alkyl, Aryl-(Ci-Ce)-alkylsulfonyl-(Ci-Ce)-alkyl, (C 3 -C 6 )-Cycloalkylsulfinyl- (Ci-Ce)-alkyl, (C3-Ce)-Cycloalkylsulfonyl-(Ci-Ce)-alkyl, Aryl, Heteroaryl, Heterocyclyl, N-[(Ci-C 6 )-Alkyl]heterocyclyl, N-[(Ci-C 6 )- Alkoxycarbonyl]heterocyclyl, N-[Aryl-(Ci-C6)- alkoxycarbonyl]heterocyclyl, N-(Arylcarbonyl)heterocyclyl, N-[(Ci-C6)- Alkylcarbonyl]heterocyclyl, N-[(Ci-C6)-Cycloalkylcarbonyl]heterocyclyl, Hydroxycarbonyl, (Ci-C6)-Alkoxycarbonyl, (C3-C6)- Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkoxycarbonyl, Aryl- (Ci-C6)-alkoxycarbonyl, Heteroaryl-(Ci-C6)-alkoxycarbonyl, (C1-C6)- Alkylaminocarbonyl, Aminocarbonyl, Bis-(Ci-C6)-alkylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Aryl-(Ci-C6)-alkylaminocarbonyl, Heteroarylaminocarbonyl, Cyano-(Ci-C6)-alkylaminocarbonyl, (C1-C6)- Haloalkylaminocarbonyl, (C2-C6)-Alkinyl-(Ci-C6)-alkylaminocarbonyl, Hydroxycarbonyl-(Ci-C6)-alkyl, (Ci-C6)-Alkoxycarbonyl-(Ci-C6)-alkyl, (C3-Ce)-Cycloalkox carbonyl-(Ci-Ce)-alkyl, (C3-C 6 )-Cycloalkyl-(Ci-C 6 )- alkoxycarbonyl-(Ci-C-6)-alkyl, Aryl-(Ci-C6)-alkoxycarbonyl-(Ci-C6)-alkyl, Heteroaryl-(Ci-C6)-alkoxycarbonyl-(Ci-C6)-alkyl, (Ci-Ce)- Alkylaminocarbonyl-(Ci-C6)-alkyl, Aminocarbonyl-(Ci-C6)-alkyl, Bis- (Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, (C3-C-6)- Cycloalkylaminocarbonyl-(Ci-C6)-alkyl, Aryl-(Ci-Ce)- alkylaminocarbonyl-(Ci-C6)-alkyl, Heteroarylaminocarbonyl-(Ci-C6)- alkyl, Cyano-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, (C1-C6)- Haloalkylaminocarbonyl-(Ci-C6)-alkyl, (C2-C6)-Alkinyl-(Ci-C6)- alkylaminocarbonyl-(Ci-C6)-alkyl, Amino-(Ci-C6)-alkyl, (Ci-Ce)- Alkylamino-(Ci-C 6 )-alkyl, (C2-Ce)-Alkenylamino-(Ci-Ce)-alkyl, (Ci-C 6) alkyl, (Ci-C 6) alkylsulfinyl (Ci-C 6) alkyl, (Ci-C 6) alkylsulfonyl (Ci-C 6) alkyl, (Ci-C 6 ) -Haloalkylsulfinyl- (Ci-C 6) alkyl, (Ci-C 6) - Haloalkylsulfonyl- (Ci-C 6) alkyl, aryl (Ci-Ce) alkylsulfinyl (Ci-Ce) alkyl, aryl - (Ci-Ce) alkylsulfonyl (Ci-Ce) alkyl, (C 3 -C 6) -Cycloalkylsulfinyl- (Ci-Ce) alkyl, (C3-Ce) -Cycloalkylsulfonyl- (Ci-Ce) alkyl , aryl, heteroaryl, heterocyclyl, N - [(Ci-C 6) -alkyl] heterocyclyl, N - [(Ci-C 6) - alkoxycarbonyl] heterocyclyl, N- [aryl (Ci-C6) - alkoxycarbonyl] heterocyclyl, N- (arylcarbonyl) heterocyclyl, N - [(Ci-C6) - alkyl carbonyl] heterocyclyl, N - [(Ci-C6) cycloalkylcarbonyl] heterocyclyl, hydroxycarbonyl, (Ci-C6) -alkoxycarbonyl, (C3-C6) - cycloalkoxycarbonyl , (C3-C6) cycloalkyl (Ci-C6) alkoxycarbonyl, aryl (Ci-C6) alkoxycarbonyl, heteroaryl (Ci-C6) -alkoxycarbonyl, (C1-C6) - alkylaminocarbonyl, aminocarbonyl, bis ( Ci-C6) alkylaminocarbonyl, (C3-C6) cycloalkylaminocarbonyl, aryl (Ci-C6) alkylaminocarbonyl, heteroarylaminocarbonyl, cyano (Ci-C6) alkylaminocarbonyl, (C1-C6) - Haloalkylaminocarbonyl, (C2-C6) alkynyl (Ci-C6) alkylaminocarbonyl, hydroxycarbonyl (Ci-C6) alkyl, (Ci-C6) -alkoxycarbonyl (Ci-C6) alkyl, (C3-Ce) -Cycloalkox carbonyl (C-Ce ) alkyl, (C3-C6) cycloalkyl (Ci-C6) - alkoxycarbonyl (Ci-C-6) alkyl, aryl (Ci-C6) alkoxycarbonyl (Ci-C6) alkyl, heteroaryl- (Ci-C6) -alkoxycarbonyl (Ci-C6) alkyl, (Ci-Ce) - alkylaminocarbonyl (Ci-C6) alkyl, aminocarbonyl (Ci-C6) alkyl, bis (Ci-C6 ) -alkylaminocarbonyl- (Ci-C6) alkyl, (C3-C6) - cycloalkylaminocarbonyl (Ci-C6) alkyl, aryl (Ci-Ce) - alkylaminocarbonyl (Ci-C6) alkyl, Heteroarylaminocarbonyl- (Ci-C6) - alkyl, cyano (Ci-C6) alkylaminocarbonyl (Ci-C6) alkyl, (C1-C6) - Haloalkylaminocarbonyl- (Ci-C6) alkyl, (C2-C6) -alkynyl (Ci-C6) - alkylaminocarbonyl (Ci-C6) alkyl, amino (Ci-C6) alkyl, (Ci-Ce) - alkylamino (C 6) alkyl, (C2-Ce) alkenylamino - (Ci-Ce) alkyl,
    Arylamino-(Ci-C6)-alkyl, Bis-(Ci-C6)-alkylamino-(Ci-C6)-alkyl, Bis- (C3-C6)-cycloalkylamino-(Ci-C6)-alkyl, Aryl-(Ci-C6)-alkylamino-(Ci-C6)- alkyl, Tris-Aryl-(Ci-Ce)-alkylamino-(Ci-Ce)-alk l, (C 3 -C 6 )- Cycloalkylamino-(Ci-C6)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkylamino- (Ci-Ce)-alkyl, (Ci-C 6 )-Haloalkylamino-(Ci-C 6 )-alkyl, (Ci-C 6 )- Alkylcarbonylamino-(Ci-C6)-alkyl, (Ci-C6)-Cycloalkylcarbonylamino- (Ci-C6)-alkyl, Arylcarbonylamino-(Ci-C6)-alkyl, Arylamino (Ci-C6) alkyl, bis (Ci-C6) alkylamino (Ci-C6) alkyl, bis (C3-C6) cycloalkylamino (Ci-C6) alkyl, aryl (Ci C6) alkylamino (Ci-C6) - alkyl, Tris-aryl (Ci-Ce) alkyl amino (Ci-Ce) alk l, (C3-C6) - cycloalkylamino (Ci-C6) alkyl, (C3-C6) cycloalkyl (Ci-C6) alkylamino (Ci-Ce) alkyl, (Ci-C 6) -Haloalkylamino- (Ci-C 6) alkyl, (Ci-C 6 ) - alkylcarbonylamino (Ci-C6) alkyl, (Ci-C6) -Cycloalkylcarbonylamino- (Ci-C6) alkyl, arylcarbonylamino (Ci-C6) alkyl,
    Heteroarylcarbonylamino-(Ci-C6)-alkyl, (Ci-C6)-Alkoxycarbonylamino- (Ci-C6)-alkyl, (C2-C6)-Alkenyloxycarbonylamino-(Ci-C6)-alkyl, Aryl- (Ci-C6)-alkoxycarbonylamino-(Ci-C6)-alkyl, Aryl-(Ci-Ce)- alkoxycarbonyl[N-(Ci-C6)-alkyl]amino-(Ci-C6)-alkyl, Heteroaryl-(Ci-C6)- alkoxycarbonylamino-(Ci-C6)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C6)- alkoxycarbonylamino-(Ci-C6)-alkyl, (C3-C6)-Cycloalkoxycarbonylamino- (Ci-C6)-alkyl, Aminocarbonylamino-(Ci-C6)-alkyl, Arylsulfonylamino- (Ci-C6)-alkyl, Heteroarylsulfonylamino-(Ci-C6)-alkyl, (C1-C6)- Alkylsulfonylamino-(Ci-C6)-alkyl, (C3-C6)-Cycloalkylsulfonylamino- (Ci-C6)-alkyl, Aminoiminoamino-(Ci-C6)-alkyl, Heteroarylcarbonylamino- (Ci-C6) alkyl, (Ci-C6) alkoxycarbonylamino (Ci-C6) alkyl, (C2-C6) -Alkenyloxycarbonylamino- (Ci-C6) alkyl, aryl (Ci-C6) - alkoxycarbonylamino (Ci-C6) alkyl, aryl (Ci-Ce) - alkoxycarbonyl [N- (Ci-C6) alkyl] amino (Ci-C6) alkyl, heteroaryl (Ci-C6) - alkoxycarbonylamino (Ci-C6) alkyl, (C3-C6) cycloalkyl (Ci-C6) - alkoxycarbonylamino (Ci-C6) alkyl, (C3-C6) -Cycloalkoxycarbonylamino- (Ci-C6) alkyl, aminocarbonylamino (Ci-C6) alkyl, arylsulfonylamino (Ci-C6) alkyl, Heteroarylsulfonylamino- (Ci-C6) alkyl, (C1-C6) - alkylsulfonylamino (Ci-C6) alkyl, (C3-C6) - Cycloalkylsulfonylamino- (Ci-C6) alkyl, Aminoiminoamino- (Ci-C6) alkyl,
    Arylsulfonylaminoiminoamino-(Ci-C6)-alkyl, (C1-C6)- Alkylaminoiminoamino-(Ci-C6)-alkyl steht, R 6 und R 8 unabhängig voneinander für H, (Ci-CeJ-Alkyl, (C2-Ce)-Alkenyl- Arylsulfonylaminoiminoamino- (Ci-C6) alkyl, (C1-C6) - Alkylaminoiminoamino- (Ci-C6) alkyl, R 6 and R 8 are independently H, (Ci-CeJ-alkyl, (C2-Ce) - alkenyl
    (Ci-Ce)-alkyl, (C 2 -Ce)-Alkinyl-(Ci-Ce)-alkyl, Aryl-(Ci-C 6 )-alkyl, (C 3 -C 6 )- Cycloalkyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkyl, Heterocyclyl, Heterocyclyl- (Ci-Ce)-alkyl, Amino-(Ci-C 6 )-alkyl, (Ci-C 6 )-Alkoxy-(Ci-C 6 )-alkyl, (Ci-Ce) alkyl, (C2 -Ce) alkynyl (Ci-Ce) alkyl, aryl (Ci-C 6) alkyl, (C 3 -C 6) - cycloalkyl, (C3-C6 ) cycloalkyl (Ci-C6) alkyl, heterocyclyl, heterocyclyl (Ci-Ce) alkyl, amino (Ci-C 6) alkyl, (Ci-C 6) alkoxy (Ci-C 6) alkyl,
    (Ci-Ce)-Alkylthio-(Ci-Ce)-alkyl, (Ci-C 6 )-Haloalkyl, (Ci-C 6 )-Alkylamino- (Ci-Ce)-alkyl, Bis-(Ci-C 6 )-alkylamino-(Ci-C 6 )-alkyl, (Ci-C 6 )- (Ci-Ce) alkylthio (Ci-Ce) alkyl, (Ci-C 6) -haloalkyl, (Ci-C 6) alkylamino (Ci-Ce) alkyl, bis (Ci-C 6) alkylamino (Ci-C 6) alkyl, (Ci-C 6) -
    Alkylcarbonylamino-(Ci-C6)-alkyl, (C3-C6)-Cycloalkylcarbonylamino- (Ci-C6)-alkyl, Arylcarbonylamino-(Ci-C6)-alkyl, (C1-C6)- Alkoxycarbonylamino-(Ci-C6)-alkyl, Aryl-(Ci-C6)-alkoxycarbonylamino- (Ci-C6)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkoxycarbonylamino-(Ci-C6)- alkyl, Aminocarbonylamino-(Ci-C6)-alkyl, Aminoiminoamino-(Ci-C6)- alkyl, Arylsulfonylaminoiminoamino-(Ci-C6)-alkyl, (C1-C6)- Alkylaminoiminoamino-(Ci-C6)-alkyl stehen, Alkylcarbonylamino (Ci-C6) alkyl, (C3-C6) -Cycloalkylcarbonylamino- (Ci-C6) alkyl, arylcarbonylamino (Ci-C6) alkyl, (C1-C6) - alkoxycarbonylamino (Ci-C6) - alkyl, aryl (Ci-C6) alkoxycarbonylamino (Ci-C6) alkyl, (C3-C6) cycloalkyl (Ci-C6) alkoxycarbonylamino (Ci-C6) - alkyl, aminocarbonylamino (Ci-C6 ) alkyl, Aminoiminoamino- (Ci-C6) - alkyl, Arylsulfonylaminoiminoamino- (Ci-C6) alkyl, (C1-C6) - Alkylaminoiminoamino- (Ci-C6) alkyl,
    R 41 für H, (Ci-Ce)-Alkyl, (C 2 -Ce)-Alkenyl-(Ci-Ce)-alkyl, (C 2 -C 6 )-Alkinyl, R 41 is H, (Ci-Ce) alkyl, (C2 -Ce) alkenyl (Ci-Ce) alkyl, (C 2 -C 6) alkynyl,
    (Ci-C6)-Alkylcarbonyl, (C3-C6)-Cycloalkylcarbonyl, Arylcarbonyl, (Ci-C6) alkylcarbonyl, (C3-C6) cycloalkylcarbonyl, arylcarbonyl,
    Heteroarylcarbonyl, (Ci-C6)-Alkoxycarbonyl, Aryl-(Ci-Ce)- alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl- (Ci-Ce)-alkoxycarbonyl, (Ci-Ce)-Alkylsulfonyl, (C 3 -C 6 )- Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C6)-Alkoxycarbonylcarbonyl, Aryl- (Ci-C6)-alkoxycarbonylcarbonyl, (Ci-C6)-Alkylaminothiocarbonyl, Heteroarylcarbonyl, (Ci-C6) alkoxycarbonyl, aryl (Ci-Ce) - alkoxycarbonyl, (C3-C6) cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-Ce) alkoxycarbonyl, (Ci-Ce) - alkylsulfonyl, (C3-C6) - cycloalkylsulphonyl, arylsulphonyl, (Ci-C6) -Alkoxycarbonylcarbonyl, aryl (Ci-C6) -alkoxycarbonylcarbonyl, (Ci-C6) -Alkylaminothiocarbonyl,
    (Ci-C6)-Alkylaminocarbonyl, Aryl-(Ci-C6)-alkyl, Hetaroaryl-(Ci-C6)-alkyl, Cyano-(Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkyl, (C 3 -C 6 )-Cycloalkyl, (C 3 -C 6 )- Cycloalkyl-(Ci-C 6 )-alkyl, (Ci-C 6 )-Alkoxy-(Ci-C 6 )-alkyl, (Ci-C 6 )- Haloalkoxy-(Ci-C 6 )-alkyl, (C2-C 6 )-Alkinyl-(Ci-C 6 )-alkyl, (Ci-C 6 )- Alkoxycarbonyl-(Ci-C6)-alkyl, Aminocarbonyl-(Ci-C6)-alkyl, (C1-C6)- Alkylaminocarbonyl-(Ci-C6)-alkyl, Bis-(Ci-C6)-alkylaminocarbonyl- (Ci-C 6 )-alkyl steht, (Ci-C6) alkylaminocarbonyl, aryl (Ci-C6) alkyl, Hetaroaryl- (Ci-C6) alkyl, cyano (Ci-C 6) alkyl, (Ci-C 6) -haloalkyl, (C 3 -C 6) -cycloalkyl, (C 3 -C 6) - cycloalkyl, (Ci-C 6) alkyl, (Ci-C 6) alkoxy (Ci-C 6) alkyl, (Ci-C 6 ) - haloalkoxy (Ci-C 6) alkyl, (C2-C6) alkynyl (Ci-C 6) alkyl, (Ci-C 6) - alkoxycarbonyl (Ci-C6) alkyl, aminocarbonyl (Ci-C6) alkyl, (C1-C6) - alkylaminocarbonyl (Ci-C6) alkyl, bis (Ci-C6) alkylaminocarbonyl (Ci-C 6) alkyl,
    im Falle der Gruppierung Q-21 ausschließlich für H oder Methyl steht, für (C 2 -C 6 )-Alkyl, (C2-C 6 )-Alkenyl-(Ci-C 6 )-alkyl, (C 2 -C 6 )-Alkinyl, (Ci-C 6 )- Alkylcarbonyl, (C3-C6)-Cycloalkylcarbonyl, Arylcarbonyl, in the case of the group Q-21 is available exclusively for H or methyl, (C 2 -C 6) alkyl, (C2-C6) alkenyl (Ci-C 6) alkyl, (C 2 -C 6) -alkynyl, (C 6) - alkylcarbonyl, (C3-C6) cycloalkylcarbonyl, arylcarbonyl,
    Heteroarylcarbonyl, (Ci-C6)-Alkoxycarbonyl, Aryl-(Ci-Ce)- alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C 3 -C6)-Cycloalkyl- (Ci-C 6 )-alkoxycarbonyl, (Ci-C 6 )-Alkylsulfonyl, (C 3 -C 6 )- Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C6)-Alkoxycarbonylcarbonyl, Aryl- (Ci-C6)-alkoxycarbonylcarbonyl, (Ci-C6)-Alkylaminothiocarbonyl, Heteroarylcarbonyl, (Ci-C6) alkoxycarbonyl, aryl (Ci-Ce) - alkoxycarbonyl, (C3-C6) cycloalkoxycarbonyl, (C 3 -C 6) cycloalkyl- (Ci-C6) -alkoxycarbonyl, (C 6) alkylsulfonyl, (C3-C6) - cycloalkylsulphonyl, arylsulphonyl, (Ci-C6) -Alkoxycarbonylcarbonyl, aryl (Ci-C6) -alkoxycarbonylcarbonyl, (Ci-C6) -Alkylaminothiocarbonyl,
    (Ci-C6)-Alkylaminocarbonyl, Aryl-(Ci-C6)-alkyl, Hetaroaryl-(Ci-C6)-alkyl, Cyano-(Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkyl, (C 3 -C 6 )-Cycloalkyl, (C 3 -C 6 )- Cycloalkyl-(Ci-C 6 )-alkyl, (Ci-C 6 )-Alkoxy-(Ci-C 6 )-alkyl, (Ci-C 6 )- Haloalkoxy-(Ci-C 6 )-alkyl, (C2-C 6 )-Alkinyl-(Ci-C 6 )-alkyl, (Ci-C 6 )- Alkoxycarbonyl-(Ci-C6)-alkyl, Aminocarbonyl-(Ci-C6)-alkyl, (C1-C6)- Alkylaminocarbonyl-(Ci-C6)-alkyl, Bis-(Ci-C6)-alkylaminocarbonyl- (Ci-C 6 )-alkyl steht, für H oder Methyl steht, für Wasserstoff, (Ci-C 6 )-Alkyl, (C2-C 6 )-Alkenyl-(Ci-C 6 )-alkyl, (C 2 -C 6 )- (Ci-C6) alkylaminocarbonyl, aryl (Ci-C6) alkyl, Hetaroaryl- (Ci-C6) alkyl, cyano (Ci-C 6) alkyl, (Ci-C 6) -haloalkyl, (C 3 -C 6) -cycloalkyl, (C 3 -C 6) - cycloalkyl, (Ci-C 6) alkyl, (Ci-C 6) alkoxy (Ci-C 6) alkyl, (Ci-C 6 ) - haloalkoxy (Ci-C 6) alkyl, (C2-C6) alkynyl (Ci-C 6) alkyl, (Ci-C 6) - alkoxycarbonyl (Ci-C6) alkyl, aminocarbonyl (Ci-C6) alkyl, (C1-C6) - alkylaminocarbonyl (Ci-C6) alkyl, bis (Ci-C6) alkylaminocarbonyl (Ci-C 6) alkyl, is H or methyl, represents hydrogen, (Ci-C 6) -alkyl, (C2-C6) alkenyl (Ci-C 6) alkyl, (C 2 -C 6) -
    Alkinyl, (Ci-C6)-Alkylcarbonyl, (C 3 -C6)-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl, (Ci-C6)-Alkoxycarbonyl, Aryl-(Ci-Ce)- alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl- (Ci-Ce)-alkoxycarbonyl, (Ci-Ce)-Alkylsulfonyl, (C 3 -C 6 )- Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C6)-Alkoxycarbonylcarbonyl, Aryl- (Ci-C6)-alkoxycarbonylcarbonyl, (Ci-C6)-Alkylaminothiocarbonyl, (Ci-C6)-Alkylaminocarbonyl, Aryl-(Ci-C6)-alkyl, Hetaroaryl-(Ci-C6)-alkyl, Cyano-(Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkyl, (C 3 -C 6 )-Cycloalkyl, (C 3 -C 6 )- Cycloalkyl-(Ci-C 6 )-alkyl, (Ci-C 6 )-Alkoxy-(Ci-C 6 )-alkyl, (Ci-C 6 )- Haloalkoxy-(Ci-C 6 )-alkyl, (C2-C 6 )-Alkinyl-(Ci-C 6 )-alkyl, (Ci-C 6 )- Alkoxycarbonyl-(Ci-C6)-alkyl, Aminocarbonyl-(Ci-C6)-alkyl, (C1-C6)- Alkylaminocarbonyl-(Ci-C6)-alkyl, Bis-(Ci-C6)-alkylaminocarbonyl- (Ci-C 6 )-alkyl steht, Alkynyl, (Ci-C6) alkylcarbonyl, (C 3 -C 6) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl, (Ci-C6) alkoxycarbonyl, aryl (Ci-Ce) - alkoxycarbonyl, (C3-C6) cycloalkoxycarbonyl, ( C3-C6) cycloalkyl (Ci-Ce) alkoxycarbonyl, (Ci-Ce) alkylsulfonyl, (C3-C6) - cycloalkylsulphonyl, arylsulphonyl, (Ci-C6) -Alkoxycarbonylcarbonyl, aryl (Ci-C6) -alkoxycarbonylcarbonyl, (Ci-C6) -Alkylaminothiocarbonyl, (Ci-C6) alkylaminocarbonyl, aryl (Ci-C6) alkyl, Hetaroaryl- (Ci-C6) alkyl, cyano (C 6) alkyl, (Ci-C 6) -haloalkyl, (C 3 -C 6) -cycloalkyl, (C 3 -C 6) - cycloalkyl, (Ci-C 6) alkyl, (Ci-C 6) alkoxy (Ci- C 6) alkyl, (Ci-C 6) - haloalkoxy (Ci-C 6) alkyl, (C2-C6) alkynyl (Ci-C 6) alkyl, (Ci-C 6) - alkoxycarbonyl - (Ci-C6) alkyl, aminocarbonyl (Ci-C6) alkyl, (C1-C6) - alkylaminocarbonyl (Ci-C6) alkyl, bis (Ci-C6) alkylaminocarbonyl (Ci-C 6 ) -alkyl,
    R 51 und R 71 unabhängig voneinander für Wasserstoff und Methyl stehen, R 51 and R 71 independently represent hydrogen and methyl,
    R 53 für Methyl steht, R 53 is methyl,
    R 61 und R 81 unabhängig voneinander für Wasserstoff und Methyl stehen, R 63 für H, Methyl steht, R 61 and R 81 independently represent hydrogen and methyl, R 63 is H, methyl,
    R 54 , R 64 , R 74 , R 84 unabhängig voneinander für Wasserstoff, Methyl stehen, R 54, R 64, R 74, R 84 are independently hydrogen, methyl,
    wobei mindestens eine der Gruppen R 54 , R 64 , R 74 , R 84 für Methyl stehen muß, wherein at least one of the groups R 54, R 64, R 74, R 84 must stand for methyl,
    V für Hydroxycarbonyl, (Ci-C6)-Alkoxycarbonyl, (C3-C6)- V hydroxycarbonyl, (Ci-C6) -alkoxycarbonyl, (C3-C6) -
    Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C6)-alkoxycarbonyl, Aminocarbonyl, (C1-C6)- Alkylaminocarbonyl, Bis-(Ci-C6)-alkylaminocarbonyl, (C1-C6)- Alkyl[(Ci-C6)-Alkoxy]aminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Aryl-(Ci-C6)-alkylaminocarbonyl, Heteroaryl-(Ci-C6)- alkylaminocarbonyl, Cyano-(Ci-C6)-alkylaminocarbonyl, (C1-C6)- Haloalkylaminocarbonyl, (C2-C6)-Alkinyl-(Ci-C6)-alkylaminocarbonyl, (Ci-C6)-Alkoxycarbonyl-(Ci-C6)-alkylaminocarbonyl, Hydroxycarbonyl- (Ci-C6)-alkylaminocarbonyl, Aminocarbonyl-(Ci-C6)- alkylaminocarbonyl, (Ci-C6)-Alkylaminocarbonyl-(Ci-C6)- alkylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl-(Ci-C6)- alkylaminocarbonyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkylaminocarbonyl steht, für 0, 1 , 2, 3, 4, 5 steht, für 1 , 2, 3, 4 steht, für Cyano, Cyano-(Ci-C6)-alkyl, Hydroxy-(Ci-C6)-alkyl, (Ci-C6)-Alkoxy- (Ci-C6)-alkyl, Hydroxycarbonyl, (Ci-C6)-Alkoxycarbonyl, (C3-C6)- Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C6)-alkoxycarbonyl, Aminocarbonyl, (C1-C6)- Alkylaminocarbonyl, Bis-(Ci-C6)-alkylaminocarbonyl, (C1-C6)- Alkyl[(Ci-C6)-Alkoxy]aminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Aryl-(Ci-C6)-alkylaminocarbonyl, Heteroaryl-(Ci-C6)- alkylaminocarbonyl, Cyano-(Ci-C6)-alkylaminocarbonyl, (C1-C6)- Haloalkylaminocarbonyl, (C2-C6)-Alkinyl-(Ci-C6)-alkylaminocarbonyl, (Ci-C6)-Alkoxycarbonylaminocarbonyl, Aryl-(Ci-Ce)- alkoxycarbonylaminocarbonyl, Hydroxycarbonyl-(Ci-C6)-alkyl, (C1-C6)- Alkoxycarbonyl-(Ci-C6)-alkyl, (C3-C6)-Cycloalkoxycarbonyl-(Ci-C6)- alkyl, (C3-Ce)-Cycloalkyl-(Ci-Ce)-alkox carbonyl-(Ci-Ce)-alkyl, (Ci-C 6 )- Alkylaminocarbonyl-(Ci-C6)-alkyl, Aminocarbonyl-(Ci-C6)-alkyl, Bis- (Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, (C3-C6)- Cycloalkylaminocarbonyl-(Ci-C6)-alkyl, Aryl-(Ci-Ce)- alkylaminocarbonyl-(Ci-C6)-alkyl, Heteroaryl-(Ci-C6)- alkylaminocarbonyl-(Ci-C6)-alkyl, Cyano-(Ci-C6)-alkylaminocarbonyl- (Ci-Ce)-alkyl, (Ci-C 6 )-Haloalkylaminocarbonyl-(Ci-C 6 )-alkyl, (C 2 -C 6 )- Alkinyl-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, (C3-C6)-Cycloalkyl- (Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, (C1-C6)- Alkoxycarbonylaminocarbonyl-(Ci-C6)-alkyl, Aryl-(Ci-C6)- alkoxycarbonylaminocarbonyl-(Ci-C6)-alkyl, Cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C6) alkoxycarbonyl, aryloxycarbonyl, aryl (Ci-C6) alkoxycarbonyl, aminocarbonyl, (C1-C6) - alkylaminocarbonyl, bis (Ci-C6) alkylaminocarbonyl, (C1-C6) - alkyl [(Ci-C6) alkoxy] aminocarbonyl, (C3-C6) cycloalkylaminocarbonyl, aryl (Ci-C6) alkylaminocarbonyl, heteroaryl (Ci-C6) - alkylaminocarbonyl, cyano (C C6) alkylaminocarbonyl, (C1-C6) - Haloalkylaminocarbonyl, (C2-C6) alkynyl (Ci-C6) alkylaminocarbonyl, (Ci-C6) -alkoxycarbonyl (Ci-C6) alkylaminocarbonyl, hydroxycarbonyl (Ci C6) alkylaminocarbonyl, aminocarbonyl (Ci-C6) - alkylaminocarbonyl, (Ci-C6) alkylaminocarbonyl (Ci-C6) - alkylaminocarbonyl, (C3-C6) -Cycloalkylaminocarbonyl- (Ci-C6) - alkylaminocarbonyl, (C3 -C6) cycloalkyl (Ci-C6) alkylaminocarbonyl, represents 0, 1, 2, 3, 4, 5, represents 1, 2, 3, 4, represents cyano, cyano (Ci-C6) - alkyl, hydroxy (Ci-C6) alkyl, (Ci-C6) alkoxy (Ci-C6) alkyl, hydroxycarbonyl, (Ci-C6) -alkoxycarbonyl, (C3-C6) - cycloalkoxycarbonyl, (C3-C6 ) cycloalkyl- (Ci-C6) alkoxycarbonyl, aryloxycarbonyl, aryl (Ci-C6) alkoxycarbonyl, aminocarbonyl, (C1-C6) - alkylaminocarbonyl, bis (Ci-C6) alkylaminocarbonyl, (C1-C6) - alkyl [(Ci-C6) alkoxy] aminocarbonyl, (C3-C6) cycloalkylaminocarbonyl, aryl (Ci-C6) alkylaminocarbonyl, heteroaryl (Ci-C6) - alkylaminocarbonyl, cyano (Ci-C6) alkylaminocarbonyl, (C1-C6) - Haloalkylaminocarbonyl, (C2-C6) alkynyl (Ci-C6) alkylaminocarbonyl, (Ci-C6) -Alkoxycarbonylaminocarbonyl, aryl (Ci-Ce) - alkoxycarbonylaminocarbonyl, hydroxycarbonyl (Ci-C6) - alkyl, (C1-C6) - alkoxycarbonyl (Ci-C6) alkyl, (C3-C6) -Cycloalkoxycarbonyl- (Ci-C6) - alkyl, (C3-Ce) cycloalkyl (Ci-Ce) -alkox carbonyl - (Ci-Ce) alkyl, (Ci-C 6) - alkylaminocarbonyl (Ci-C6) alkyl, aminocarbonyl (Ci-C6) alkyl, bis (Ci-C6) alkylaminocarbonyl (Ci-C6 ) alkyl, (C3-C6) - cycloalkylaminocarbonyl (Ci-C6) alkyl, aryl (Ci-Ce) - alkylaminocarbonyl (Ci-C6) alkyl, heteroaryl (Ci-C6) - alkylaminocarbonyl (Ci C6) alkyl, cyano (Ci-C6) alkylaminocarbonyl (Ci-Ce) alkyl, (Ci-C 6) -Haloalkylaminocarbonyl- (Ci-C 6) alkyl, (C 2 -C 6) - alkynyl (Ci-C6) alkylaminocarbonyl (Ci-C6) alkyl, (C3-C6) cycloalkyl (Ci-C6) alkylaminocarbonyl (Ci-C6) alkyl, (C1-C6) - Alkoxycarbonylaminocarbonyl- (Ci-C6) alkyl, aryl (Ci-C6) - alkoxycarbonylaminocarbonyl- (Ci-C6) alkyl,
    (Ci-C6)-Alkoxycarbonyl-(Ci-C6)-alkylaminocarbonyl, Hydroxycarbonyl- (Ci-C6)-alkylaminocarbonyl, Aminocarbonyl-(Ci-C6)- alkylaminocarbonyl, (Ci-C6)-Alkylaminocarbonyl-(Ci-C6)- alkylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl-(Ci-C6)- alkylaminocarbonyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkylaminocarbonyl, (C3-Ce)-Cycloalkyl-(Ci-Ce)-alkylaminocarbonyl-(Ci-Ce)-alkyl, (C 2 -C 6 )- Alkenyloxycarbonyl, (C2-C6)-Alkenyloxycarbonyl-(Ci-C6)-alkyl, (C2-C6)- Alkenylaminocarbonyl, (C2-C6)-Alkenyl-(Ci-C6)-alkylaminocarbonyl, (C2-Ce)-Alkenylaminocarbonyl-(Ci-Ce)-alkyl, (C2-C 6 )-Alkenyl-(Ci-C 6 )- alkylaminocarbonyl-(Ci-C6)-alkyl steht. (Ci-C6) -alkoxycarbonyl (Ci-C6) alkylaminocarbonyl, hydroxycarbonyl (Ci-C6) alkylaminocarbonyl, aminocarbonyl (Ci-C6) - alkylaminocarbonyl, (Ci-C6) alkylaminocarbonyl (Ci-C6) - alkylaminocarbonyl, (C3-C6) -Cycloalkylaminocarbonyl- (Ci-C6) - alkylaminocarbonyl, (C3-C6) cycloalkyl (Ci-C6) alkylaminocarbonyl, (C3-Ce) cycloalkyl (Ci-Ce) -alkylaminocarbonyl- (Ci-Ce) alkyl, (C2-C6) - alkenyloxycarbonyl, (C2-C6) -Alkenyloxycarbonyl- (Ci-C6) alkyl, (C2-C6) - alkenylaminocarbonyl, (C2-C6) -alkenyl (Ci-C6) alkylaminocarbonyl, (C2-Ce) -Alkenylaminocarbonyl- (Ci-Ce) alkyl, (C2-C6) -alkenyl (Ci-C 6) - alkylaminocarbonyl (Ci-C6) alkyl ,
    Verwendung von Verbindungen der allgemeinen Formel (I) oder deren Salze gemäß Anspruch 1 , wobei Use of compounds of general formula (I) or salts thereof according to claim 1, wherein
    Q für die Gruppierungen Q represents the groups
    Figure imgf000314_0001
    Q-1 Q-20 Q-21 Q-1 Q-20 Q-21
    Figure imgf000314_0002
    Q-22 Q-23 Q-24 steht, und wobei die Reste R 4 bis R 8 , und R 41 bis R 84 sowie Y und m und p jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zum Schwefelatom der S0 2 -Gruppe steht; Q-22 Q-23 Q-24 is, and where the radicals R 4 to R 8 and R 41 to R 84 and Y and m and p are each as defined in accordance with the following definitions and where the arrow represents a bond to the sulfur atom the S0 2 group; A 1 , A 2 , A 3 gleich oder verschieden sind und unabhängig voneinander für N A 1, A 2, A 3 are identical or different and are each independently N
    (Stickstoff) oder die Gruppierung CW stehen, wobei jedoch in keinem Fall mehr als zwei N-Atome benachbart sind, und wobei W in der Gruppierung CW jeweils gleiche oder verschiedene Bedeutungen gemäß der nachstehenden Definition hat, (Nitrogen) or the group CW are, but in no case more than two N atoms are adjacent, and wherein W in the group CW has the same or different meanings as defined below,
    W jeweils für Wasserstoff, Nitro, Amino, Cyano, Thiocyanato, W each represent hydrogen, nitro, amino, cyano, thiocyanato,
    Isothiocyanato, Halogen, (Ci-C 4 )-Alkyl, (C 3 -C 6 )-Cycloalkyl, (C 2 -C 4 )- Alkenyl, (C 2 -C 4 )-Alkinyl, Aryl, Aryl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkoxy, Heteroaryl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, (C3-C5)- Halocycloalkyl, (Ci-C 4 )-Alkoxy, (Ci-C 4 )-Haloalkoxy, Aryloxy, Isothiocyanato, halogen, (Ci-C 4) -alkyl, (C 3 -C 6) -cycloalkyl, (C 2 -C 4) - alkenyl, (C 2 -C 4) -alkynyl, aryl, aryl- (Ci- C 4) alkyl, aryl (Ci-C4) alkoxy, heteroaryl, (Ci-C4) alkoxy (Ci-C4) alkyl, (Ci-C4) -haloalkyl, (C3-C5 ) - halocycloalkyl, (Ci-C4) -alkoxy, (Ci-C4) haloalkoxy, aryloxy,
    Heteroaryloxy, (C3-C6)-Cycloalkyloxy, (C3-C6)-Cycloalkyl-(Ci-C 4 )- alkoxy, (Ci-C 4 )-Alkoxycarbonyl, (Ci-C 4 )-Alkoxycarbonyl-(Ci-C 4 )-alkyl, Hydroxycarbonyl, Aminocarbonyl, (Ci-C 4 )-Alkylaminocarbonyl, (C3-C6)- Cycloalkylaminocarbonyl, Cyano-(Ci-C 4 )-alkylaminocarbonyl, (C2-C 4 )- Alkenylaminocarbonyl, (C2-C 4 )-Alkinylaminocarbonyl, (Ci-C 4 )- Alkylamino, (Ci-C 4 )-Alkylthio, (Ci-C 4 )-Haloalkylthio, Bis-(Ci-C 4 )- alkylamino, (C3-C6)-Cycloalkylamino, (Ci-C 4 )-Alkylcarbonylamino, (C3-C6)-Cycloalkylcarbonylamino, Formylamino, (Ci-C 4 )- Haloalkylcarbonylamino, (Ci-C 4 )-Alkoxycarbonylamino, (Ci-C 4 )- Alkylaminocarbonylamino, Bis-[(Ci-C 4 )-Alkyl]-aminocarbonyl-amino, (Ci-C 4 )-Alkylsulfonylamino, (C3-C6)-Cycloalkylsulfonylamino, Heteroaryloxy, (C3-C6) -cycloalkyloxy, (C3-C6) cycloalkyl (Ci-C4) - alkoxy, (Ci-C4) alkoxycarbonyl, (Ci-C4) alkoxycarbonyl (C 4 ) alkyl, hydroxycarbonyl, aminocarbonyl, (Ci-C4) alkylaminocarbonyl, (C3-C6) - cycloalkylaminocarbonyl, cyano (Ci-C4) alkylaminocarbonyl, (C2-C4) - alkenylaminocarbonyl, (C2-C4 ) -Alkinylaminocarbonyl, (Ci-C 4) - alkylamino, (Ci-C4) -alkylthio, (C 4) haloalkylthio, bis (C 4) - alkylamino, (C3-C6) cycloalkylamino, (Ci-C 4) alkylcarbonylamino, (C3-C6) -Cycloalkylcarbonylamino, formylamino, (Ci-C4) - Haloalkylcarbonylamino, (Ci-C4) alkoxycarbonylamino, (Ci-C4) - alkylaminocarbonylamino, bis - [( Ci-C4) alkyl] aminocarbonyl-amino, (Ci-C4) alkylsulfonylamino, (C3-C6) -Cycloalkylsulfonylamino,
    Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl-(Ci-C 4 )- haloalkylamino, Amino-(Ci-C 4 )-alkylsulfonyl, Amino-(Ci-C 4 )- haloalkylsulfonyl, (Ci-C 4 )-Alkylsulfonyl, (C3-C6)-Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C 4 )-Alkylsulfinyl, (C3-C6)-Cycloalkylsulfinyl, Arylsulfinyl, N,S-Di-(Ci-C 4 )-alkylsulfonimidoyl, S-(Ci-C 4 )-Alkylsulfonimidoyl, Arylsulfonylamino, Hetarylsulfonylamino, sulfonyl (Ci-C4) - haloalkylamino, amino (Ci-C4) alkylsulphonyl, amino (Ci-C4) - haloalkylsulfonyl, (Ci-C4) alkylsulphonyl, (C3-C6 ) cycloalkylsulfonyl, arylsulphonyl, (Ci-C4) alkylsulfinyl, (C3-C6) -Cycloalkylsulfinyl, arylsulfinyl, N, S-di- (Ci-C4) -alkylsulfonimidoyl, S- (Ci-C4) -Alkylsulfonimidoyl .
    (Ci-C 4 )-Alkylsulfonylaminocarbonyl, (C3-C6)- Cycloalkylsulfonylaminocarbonyl, (C3-C6)-Cycloalkylaminosulfonyl, Aryl-(Ci-C 4 )-alkylcarbonylamino, (C3-C6)-Cycloalkyl-(Ci-C 4 )- alkylcarbonylamino, Heteroarylcarbonylamino, (Ci-C 4 )-Alkoxy-(Ci-C 4 )- alkylcarbonylamino, Hydroxy-(Ci-C 4 )-alkylcarbonylamino steht, für H, Nitro, Amino, Cyano, Halogen, (Ci-C 4 )-Alkyl, (C 3 -C 6 )-Cycloalkyl, (C 2 -C 4 )-Alkenyl, (C 2 -C 4 )-Alkinyl, Aryl, Aryl-(Ci-C 4 )-alkyl, Heteroaryl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, (C 3 -C 6 )-Halocycloalkyl, (Ci-C 4 )-Alkoxy, (Ci-C 4 )-Haloalkoxy, (Ci-C 4 )-Alkylthio, (Ci-C 4 )- Haloalkylthio, (Ci-C 4 )-Alkoxycarbonyl, Hydroxycarbonyl, (Ci-C4) -Alkylsulfonylaminocarbonyl, (C3-C6) - Cycloalkylsulfonylaminocarbonyl, (C3-C6) -Cycloalkylaminosulfonyl, aryl (Ci-C 4) alkylcarbonylamino, (C3-C6) cycloalkyl (Ci-C4) - alkylcarbonylamino, heteroarylcarbonylamino, (Ci-C 4) alkoxy- (Ci-C4) - alkylcarbonylamino, hydroxy (Ci-C 4) alkyl-carbonylamino, represents H, nitro, amino, cyano, halogen, (Ci-C 4) -alkyl, (C 3 -C 6) -cycloalkyl, (C 2 -C 4) -alkenyl, (C 2 -C 4) -alkynyl, aryl, aryl- (Ci-C 4) alkyl, heteroaryl, (Ci-C4) alkoxy (Ci-C4) alkyl, (Ci-C4) -haloalkyl, (C3-C6) halocycloalkyl, (Ci-C4) alkoxy, (C 4) haloalkoxy, (Ci-C4) -alkylthio, (Ci-C4) - haloalkylthio, (Ci-C4) alkoxycarbonyl, hydroxycarbonyl,
    Aminocarbonyl, (Ci-C 4 )-Alkylaminocarbonyl, (Ci-C 4 )-Alkylamino, Bis- (Ci-C 4 )-alkylamino, (C3-C6)-Cycloalkylamino, (Ci-C 4 )- Alkylcarbonylamino, (C3-C6)-Cycloalkylcarbonylamino, Formylamino, (Ci-C 4 )-Haloalkylcarbonylamino, (Ci-C 4 )-Alkoxycarbonylamino, Aminocarbonyl, (Ci-C4) alkylaminocarbonyl, (Ci-C4) alkylamino, bis (Ci-C4) alkylamino, (C3-C6) cycloalkylamino, (Ci-C4) - alkylcarbonylamino, (C3 C6) -Cycloalkylcarbonylamino, formylamino, (Ci-C4) -Haloalkylcarbonylamino, (Ci-C4) alkoxycarbonylamino,
    [(Ci-C 4 )-Alkyl-]aminocarbonyl-amino, Sulfonylamino, (Ci-C 4 )- Alkylsulfonylamino, (Ci-C 4 )-Haloalkylsulfonylamino, (C3-C6)- Cycloalkylsulfonylamino, Amino-(Ci-C 4 )-alkylsulfonyl, Amino-(Ci-C 4 )- haloalkylsulfonyl, (Ci-C 4 )-Alkylsulfonyl, (C3-C6)-Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C 4 )-Alkylsulfinyl, (C3-C6)-Cycloalkylsulfinyl, Arylsulfinyl, N,S-Di-(Ci-C 4 )-alkylsulfonimidoyl, S-(Ci-C 4 )-Alkylsulfonimidoyl, [(Ci-C4) -alkyl] aminocarbonyl-amino, sulfonylamino, (Ci-C4) - alkylsulfonylamino, (Ci-C4) -Haloalkylsulfonylamino, (C3-C6) - cycloalkylsulfonylamino, amino (Ci-C 4 ) alkylsulfonyl, amino (Ci-C4) - haloalkylsulfonyl, (Ci-C4) alkylsulphonyl, (C3-C6) cycloalkylsulfonyl, arylsulphonyl, (Ci-C4) alkylsulfinyl, (C3-C6) -Cycloalkylsulfinyl , arylsulfinyl, N, S-di- (Ci-C4) -alkylsulfonimidoyl, S- (Ci-C4) -Alkylsulfonimidoyl,
    (Ci-C 4 )-Alkylsulfonylaminocarbonyl, (C3-C6)- Cycloalkylsulfonylaminocarbonyl, (C3-C6)-Cycloalkylaminosulfonyl, Amino-(Ci-C 4 )-alkyl, Amino-(C2-C 4 )-alkenyl, (C2-C 4 )-Alkenylamino, (C2- C 4 )-Alkenylimino steht, für H, Nitro, Amino, Cyano, Halogen, (Ci-C 4 )-Alkyl, (C 3 -C 6 )-Cycloalkyl, (C 2 -C 4 )-Alkenyl, (C 2 -C 4 )-Alkinyl, Aryl, Aryl-(Ci-C 4 )-alkyl, Heteroaryl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, (C 3 -C 6 )-Halocycloalkyl, (Ci-C 4 )-Alkoxy, (Ci-C 4 )-Haloalkoxy, (Ci-C 4 )-Alkylthio, (Ci-C 4 )- Haloalkylthio, (Ci-C 4 )-Alkoxycarbonyl, Hydroxycarbonyl, (Ci-C4) -Alkylsulfonylaminocarbonyl, (C3-C6) - Cycloalkylsulfonylaminocarbonyl, (C3-C6) -Cycloalkylaminosulfonyl, amino (Ci-C4) alkyl, amino (C2-C4) -alkenyl, (C2 C 4) alkenylamino, (C2-C 4) -Alkenylimino, represents H, nitro, amino, cyano, halogen, (Ci-C 4) alkyl, (C 3 -C 6) -cycloalkyl, (C 2 - C 4) alkenyl, (C 2 -C 4) -alkynyl, aryl, aryl- (Ci-C 4) alkyl, heteroaryl, (Ci-C 4) alkoxy (Ci-C 4) alkyl, ( Ci-C4) -haloalkyl, (C3-C6) halocycloalkyl, (Ci-C4) -alkoxy, (Ci-C4) haloalkoxy, (Ci-C4) -alkylthio, (C 4 ) - haloalkylthio, (Ci-C4) alkoxycarbonyl, hydroxycarbonyl,
    Aminocarbonyl, (Ci-C 4 )-Alkylaminocarbonyl, (Ci-C 4 )-Alkylamino, Bis- (Ci-C 4 )-alkylamino, (C3-C6)-Cycloalkylamino, (Ci-C 4 )- Alkylcarbonylamino, (C3-C6)-Cycloalkylcarbonylamino, Formylamino, (Ci-C 4 )-Haloalkylcarbonylamino, (Ci-C 4 )-Alkoxycarbonylamino, Aminocarbonyl, (Ci-C4) alkylaminocarbonyl, (Ci-C4) alkylamino, bis (Ci-C4) alkylamino, (C3-C6) cycloalkylamino, (Ci-C4) - alkylcarbonylamino, (C3 C6) -Cycloalkylcarbonylamino, formylamino, (Ci-C4) -Haloalkylcarbonylamino, (Ci-C4) alkoxycarbonylamino,
    [(Ci-C 4 )-Alkyl-]-aminocarbonyl-amino, Sulfonylamino, (Ci-C 4 )- Alkylsulfonylamino, (Ci-C 4 )-Haloalkylsulfonylamino, (C3-C6)- Cycloalkylsulfonylamino, Amino-(Ci-C 4 )-alkylsulfonyl, Amino-(Ci-C 4 )- haloalkylsulfonyl, (Ci-C 4 )-Alkylsulfonyl, (C3-C6)-Cycloalkylsulfonyl, Aryisuifonyi, (Ci-C 4 )-Alkylsulfinyl, (C3-C6)-Cycloalkylsulfinyl, Arylsulfinyl, N,S-Di-(Ci-C 4 )-alkylsulfonimidoyl, S-(Ci-C 4 )-Alkylsulfonimidoyl, [(Ci-C4) alkyl -] - aminocarbonyl-amino, sulfonylamino, (Ci-C4) - alkylsulfonylamino, (Ci-C4) -Haloalkylsulfonylamino, (C3-C6) - cycloalkylsulfonylamino, amino (Ci-C 4) alkylsulfonyl, amino (Ci-C4) - haloalkylsulfonyl, (Ci-C4) alkylsulphonyl, (C3-C6) cycloalkylsulfonyl, Aryisuifonyi, (Ci-C4) alkylsulfinyl, (C3-C6) - cycloalkylsulfinyl, arylsulfinyl, N, S-di- (Ci-C4) -alkylsulfonimidoyl, S- (Ci-C4) -Alkylsulfonimidoyl,
    (Ci-C 4 )-Alkylsulfonylaminocarbonyl, (C3-C6)- Cycloalkylsulfonylaminocarbonyl, (C3-C6)-Cycloalkylaminosulfonyl, Amino-(Ci-C 4 )-alkyl, Amino-(C2-C 4 )-alkenyl, (C2-C 4 )-Alkenylamino, (C2- C 4 )-Alkenylimino steht, (Ci-C4) -Alkylsulfonylaminocarbonyl, (C3-C6) - Cycloalkylsulfonylaminocarbonyl, (C3-C6) -Cycloalkylaminosulfonyl, amino (Ci-C4) alkyl, amino (C2-C4) -alkenyl, (C2 C 4) alkenylamino, (C2- C4) -Alkenylimino stands,
    R 1 und R 2 mit den Atomen, an die sie gebunden sind, einen vollständig R 1 and R 2 with the atoms to which they are attached form a fully
    gesättigten, teilgesättigten oder vollständig ungesättigten, saturated, partially saturated or fully unsaturated,
    gegebenenfalls durch Heteroatome unterbrochenen und optionally interrupted by hetero atoms and
    gegebenenfalls weiter durch W substituierten 5 bis 7-gliedrigen Ring bilden, und wobei sie im Falle der Verbindungen der allgemeinen Formel (I) mit den Gruppierungen Q-21 und Q-23 einen optionally further form to 7-membered ring substituted by W 5, and wherein a in the case of compounds of general formula (I) with the moieties Q-21 and Q-23
    entsprechenden Ring bilden müssen. must make appropriate ring.
    R 1 und A 3 , wenn A 3 für eine Gruppe CW steht, mit den Atomen, an die sie R 1 and A 3, when A 3 is a group CW, with the atoms to which they
    gebunden sind, einen vollständig gesättigten, teilgesättigten oder vollständig ungesättigten, gegebenenfalls durch Heteroatome unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7- gliedrigen Ring bilden, are attached form a fully saturated, partially saturated or fully unsaturated, optionally interrupted by hetero atoms and optionally further substituted 5 to 7-membered ring form,
    X für eine direkte Bindung oder für eine Gruppierung (CHR 3 ) n steht, und wobei R 3 in der Gruppierung (CHR 3 ) n jeweils gleiche oder X is a direct bond or a group (CHR 3) n and wherein R 3 in the group (CHR 3) n, the same or
    verschiedene Bedeutungen gemäß der nachstehenden Definition hat, n für 0, 1 steht different meanings as defined below, has n is 0, 1 is
    R 3 für H, (Ci-C 4 )-Alkyl, (C 2 -C 4 )-Alkenyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, R 3 is H, (Ci-C 4) -alkyl, (C 2 -C 4) alkenyl (Ci-C 4) alkyl, (Ci-C 4) -haloalkyl,
    (C 3 -C 6 )-Cycloalkyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkyl, Heteroaryl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )- Haloalkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylthio-(Ci-C 4 )-alkyl, (Ci-C 4 )- Haloalkylthio-(Ci-C 4 )-alkyl steht, für H, (Ci-C 4 )-Alkyl, (C 2 -C 4 )-Alkenyl-(Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkinyl, (C 3 -C 6) -cycloalkyl, (C 3 -C 6) cycloalkyl (Ci-C 4) alkyl, aryl (Ci-C 4) -alkyl, heteroaryl- (Ci-C 4) -alkyl , (Ci-C4) alkoxy (Ci-C4) alkyl, (Ci-C4) - haloalkoxy (Ci-C4) alkyl, (Ci-C4) alkylthio (C 4) alkyl, (Ci-C 4) - Haloalkylthio- (Ci-C 4) -alkyl, H, (Ci-C 4) -alkyl, (C 2 -C 4) alkenyl (Ci-C 4) -alkyl, (C 2 -C 4) alkynyl,
    (Ci-C 4 )-Alkylcarbonyl, (C3-C6)-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl, (Ci-C 4 )-Alkoxycarbonyl, Aryl-(Ci-C 4 )- alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C 3 -C6)-Cycloalkyl- (Ci-C 4 )-alkoxycarbonyl, (Ci-C 4 )-Alkylsulfonyl, (C 3 -C 6 )- Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C 4 )-Alkoxycarbonylcarbonyl, Aryl- (Ci-C 4 )-alkoxycarbonylcarbonyl, (Ci-C 4 )-Alkylaminothiocarbonyl, (Ci-C4) alkylcarbonyl, (C3-C6) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl, (Ci-C4) alkoxycarbonyl, aryl (Ci-C4) - alkoxy, (C3-C6) cycloalkoxycarbonyl, ( C 3 -C 6) cycloalkyl- (Ci-C4) -alkoxycarbonyl, (Ci-C4) alkylsulphonyl, (C3-C6) - cycloalkylsulphonyl, arylsulphonyl, (Ci-C4) -Alkoxycarbonylcarbonyl, aryl ( Ci-C4) -alkoxycarbonylcarbonyl, (Ci-C4) -Alkylaminothiocarbonyl,
    (Ci-C 4 )-Alkylaminocarbonyl, Aryl-(Ci-C 4 )-alkyl, Hetaroaryl-(Ci-C 4 )-alkyl, Cyano-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, (C 3 -C 6 )-Cycloalkyl, (C 3 -C 6 )- Cycloalkyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )- Haloalkoxy-(Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkinyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkoxycarbonyl-(Ci-C 4 )-alkyl, Aminocarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylaminocarbonyl-(Ci-C 4 )-alkyl, Bis-(Ci-C 4 )-alkylaminocarbonyl- (Ci-C 4 )-alkyl steht, für Halogen, (C2-C 4 )-Alkyl, (Ci-C 4 )-Alkoxy, (Ci-C 4 )-Alkoxycarbonyloxy, (C 2 -C 4 )-Alkenyl, (C 2 -C 4 )-Haloalkenyl, (C 2 -C 4 )-Alkenyl-(Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkinyl, (C 2 -C 4 )-Alkinyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkyl, Bisaryl- (Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkoxyaryl-(Ci-C 4 )-alkyl, Aryloxyaryl-(Ci-C 4 )- alkyl, (Ci-C 4 )-Alkoxyaryl-(Ci-C 4 )-alkyl, Heteroaryl-(Ci-C 4 )-alkyl, (Ci-C4) alkylaminocarbonyl, aryl (Ci-C4) alkyl, Hetaroaryl- (Ci-C4) alkyl, cyano (Ci-C4) alkyl, (Ci-C4) -haloalkyl , (C 3 -C 6) -cycloalkyl, (C 3 -C 6) - cycloalkyl, (Ci-C 4) alkyl, (Ci-C 4) alkoxy (Ci-C 4) alkyl, (C C4) - haloalkoxy (Ci-C4) alkyl, (C2-C4) alkynyl (Ci-C4) alkyl, (Ci-C4) - alkoxycarbonyl (Ci-C4) alkyl, aminocarbonyl (Ci-C4) alkyl, (Ci-C4) - alkylaminocarbonyl (Ci-C4) alkyl, bis (Ci-C4) alkylaminocarbonyl (Ci-C4) - alkyl, halogen, (C2-C 4) alkyl, (Ci-C 4) alkoxy, (Ci-C4) alkoxycarbonyloxy, (C 2 -C 4) -alkenyl, (C 2 -C 4) haloalkenyl, (C 2 -C 4) alkenyl, (Ci-C 4) alkyl, (C 2 -C 4) -alkynyl, (C 2 -C 4) alkynyl (Ci-C 4) -alkyl , aryl (Ci-C4) alkyl, bisaryl (Ci-C4) alkyl, aryl (Ci-C4) -alkoxyaryl- (Ci-C4) alkyl, Aryloxyaryl- (Ci-C 4 ) - alkyl, (Ci-C4) -Alkoxyaryl- (Ci-C4) alkyl, heteroaryl (Ci-C4) alkyl,
    Heterocyclyl-(Ci-C 4 )-alkyl, N-(Ci-C 4 )-Alkylheterocyclyl-(Ci-C 4 )-alkyl, N- [(Ci-C 4 )-Alkoxycarbonyl]heterocyclyl-(Ci-C 4 )-alkyl, N-(Aryl-(Ci-C 4 )- alkoxycarbonyl)heterocyclyl-(Ci-C 4 )-alkyl, N-(Arylcarbonyl)heterocyclyl- (Ci-C 4 )-alkyl, N-[(Ci-C 4 )-Alkylcarbonyl]heterocyclyl-(Ci-C 4 )-alkyl, N- [(C3-C6)-Cycloalkylcarbonyl]heterocyclyl-(Ci-C 4 )-alkyl, Cyano-(Ci-C 4 )- alkyl, (Ci-C 4 )-Haloalkyl, (C 3 -C 6 )-Cycloalkyl, (C 3 -C 6 )-Halocycloalkyl, (C 4 -C 6 )-Cycloalkenyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C 4 )-alkyl, (C 3 -C 6 )- Cycloalkenyl-(Ci-C 4 )-alkyl, Hydroxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxy- (Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkoxy-(Ci-C 4 )-alkyl, Aryloxy-(Ci-C 4 )-alkyl, Aryl-(Ci-C4)-alkoxy-(Ci-C 4 )-alkyl, Heteroaryl-(Ci-C 4 )-alkoxy-(Ci-C 4 )- alkyl, (C 3 -C 6 )-Cycloalkoxy-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C 4 )- alkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylcarbonyloxy-(Ci-C 4 )-alkyl, Heterocyclyl (Ci-C4) alkyl, N- (Ci-C4) -Alkylheterocyclyl- (Ci-C4) alkyl, N- [(Ci-C4) alkoxycarbonyl] heterocyclyl (Ci-C 4 ) alkyl, N- (aryl (Ci-C4) - alkoxycarbonyl) heterocyclyl- (Ci-C 4) alkyl, N- (arylcarbonyl) heterocyclyl- (Ci-C 4) -alkyl, N - [(C C4) alkyl-carbonyl] heterocyclyl (Ci-C4) alkyl, N- [(C3-C6) cycloalkylcarbonyl] heterocyclyl (Ci-C4) alkyl, cyano (Ci-C4) - alkyl , (Ci-C 4) -haloalkyl, (C 3 -C 6) -cycloalkyl, (C 3 -C 6) halocycloalkyl, (C 4 -C 6) -cycloalkenyl, (C 3 -C 6) cycloalkyl (Ci-C 4) alkyl, (C 3 -C 6) - cycloalkenyl, (Ci-C 4) alkyl, hydroxy (Ci-C 4) alkyl, (Ci-C 4) alkoxy- (C -C 4) alkyl, (Ci-C 4) haloalkoxy (Ci-C 4) alkyl, aryloxy (Ci-C 4) alkyl, aryl (Ci-C4) alkoxy (Ci-C 4) -alkyl, heteroaryl- (Ci-C 4) alkoxy (Ci-C 4) - alkyl, (C 3 -C 6) cycloalkoxy (Ci-C 4) alkyl, (C 3 -C 6 ) cycloalkyl- (Ci-C4) - alkoxy (Ci-C4) alkyl, (Ci-C4) alkylcarbonyloxy (Ci-C4) alkyl,
    Arylcarbonyloxy-(Ci-C 4 )-alkyl, Heteroarylcarbonyloxy-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkylcarbonyloxy-(Ci-C 4 )-alkyl, Arylsulfonyloxy-(Ci-C 4 )- alkyl, (Ci-C 4 )-Alkylsulfonyloxy-(Ci-C 4 )-alkyl, Hydrothio-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylthio-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkylthio-(Ci-C 4 )-alkyl, Aryl- (Ci-C 4 )-alkylthio-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkylthio-(Ci-C 4 )-alkyl, Arylthio-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylsulfinyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylsulfonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkylsulfinyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkylsulfonyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkylsulfinyl- (Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkylsulfonyl-(Ci-C 4 )-alkyl, (C 3 -C 6 )- Cycloalkylsulfinyl-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkylsulfonyl-(Ci-C 4 )-alkyl, Aryl, Heteroaryl, Heterocyclyl, N-[(Ci-C 4 )-Alkyl]heterocyclyl, N-[(Ci-C 4 )- Alkoxycarbonyl]heterocyclyl, N-[Aryl-(Ci-C 4 )- alkoxycarbonyl]heterocyclyl, N-(Arylcarbonyl)heterocyclyl, N-[(Ci-C 4 )- Alkylcarbonyl]heterocyclyl, N-[(Ci-C 4 )-Cycloalkylcarbonyl]heterocyclyl, Hydroxycarbonyl, (Ci-C 4 )-Alkoxycarbonyl, (C 3 -C6)- Cycloalkoxycarbonyl, (C 3 -C6)-Cycloalkyl-(Ci-C 4 )-alkoxycarbonyl, Aryl- (Ci-C 4 )-alkoxycarbonyl, Heteroaryl-(Ci-C 4 )-alkoxycarbonyl, (Ci-C 4 )- Alkylaminocarbonyl, Aminocarbonyl, Bis-(Ci-C 4 )-alkylaminocarbonyl, (C 3 -C6)-Cycloalkylaminocarbonyl, Aryl-(Ci-C 4 )-alkylaminocarbonyl, Heteroarylaminocarbonyl, Cyano-(Ci-C 4 )-alkylaminocarbonyl, (Ci-C 4 )- Haloalkylaminocarbonyl, (C2-C 4 )-Alkinyl-(Ci-C 4 )-alkylaminocarbonyl, Hydroxycarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxycarbonyl-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkoxycarbonyl-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C 4 )- alkoxycarbonyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkoxycarbonyl-(Ci-C 4 )-alkyl, Heteroaryl-(Ci-C 4 )-alkoxycarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylaminocarbonyl-(Ci-C 4 )-alkyl, Aminocarbonyl-(Ci-C 4 )-alkyl, Bis- (Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, (C 3 -C6)- Cycloalkylaminocarbonyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )- alkylaminocarbonyl-(Ci-C 4 )-alkyl, Heteroarylaminocarbonyl-(Ci-C 4 )- alkyl, Cyano-(Ci-C4)-alkylaminocarbonyl-(Ci-C4)-alkyl, (C1-C4)- Haloalkylaminocarbonyl-(Ci-C4)-alkyl, (C2-C4)-Alkinyl-(Ci-C4)- alkylaminocarbonyl-(Ci-C4)-alkyl, Amino-(Ci-C4)-alkyl, (C1-C4)- Alkylamino-(Ci-C4)-alkyl, (C2-C4)-Alkenylamino-(Ci-C4)-alkyl, Arylcarbonyloxy (Ci-C4) alkyl, Heteroarylcarbonyloxy- (Ci-C4) alkyl, (C3-C6) -Cycloalkylcarbonyloxy- (Ci-C4) alkyl, arylsulfonyloxy (Ci-C4) - alkyl, (Ci-C 4) alkylsulfonyloxy (Ci-C4) alkyl, Hydrothio- (Ci-C4) alkyl, (Ci-C4) alkylthio (Ci-C4) alkyl, (Ci C 4) -Haloalkylthio- (Ci-C 4) alkyl, aryl (Ci-C 4) alkylthio (Ci-C 4) alkyl, (C 3 -C 6) cycloalkylthio (Ci-C 4 ) alkyl, arylthio (Ci-C4) alkyl, (Ci-C4) alkylsulphinyl (Ci-C4) alkyl, (Ci-C4) - alkylsulphonyl (Ci-C4) alkyl , (Ci-C4) -Haloalkylsulfinyl- (Ci-C4) alkyl, (Ci-C4) -Haloalkylsulfonyl- (Ci-C4) alkyl, aryl (Ci-C4) alkylsulphinyl (Ci -C 4) alkyl, aryl (Ci-C 4) alkylsulfonyl (Ci-C 4) alkyl, (C 3 -C 6) - Cycloalkylsulfinyl- (Ci-C 4) alkyl, (C 3 - C 6) -Cycloalkylsulfonyl- (Ci-C 4) alkyl, aryl, heteroaryl, heterocyclyl, N - [(Ci-C 4) -alkyl] heterocyclyl, N - [(Ci-C4) - alkoxycarbonyl] heterocyclyl, N - [aryl (Ci-C4) - alkoxycarbonyl] heterocyclyl, N- (arylcarbonyl) heterocyclyl, N - [(Ci-C4) - alkyl carbonyl] heterocyclyl, N - [(Ci-C4) -cycloalkylcarbonyl] heterocyclyl, hydroxycarbonyl, (Ci-C4) -alkoxycarbonyl, (C 3 -C 6) - cycloalkoxycarbonyl, (C 3 -C 6) cycloalkyl- (Ci-C4) alkoxycarbonyl, aryl (Ci-C4) alkoxycarbonyl, heteroaryl - (Ci-C4) -alkoxycarbonyl, (Ci-C4) - alkylaminocarbonyl, aminocarbonyl, bis (Ci-C4) alkylaminocarbonyl, (C3-C6) cycloalkylaminocarbonyl, aryl (Ci-C4) - alkylaminocarbonyl, heteroarylaminocarbonyl, cyano (Ci-C4) alkylaminocarbonyl, (Ci-C4) - Haloalkylaminocarbonyl, (C2-C4) alkynyl (Ci-C4) alkylaminocarbonyl, hydroxycarbonyl (C 4) alkyl, (Ci-C 4) alkoxycarbonyl (Ci-C 4) alkyl, (C 3 -C 6) -Cycloalkoxycarbonyl- (Ci-C 4) alkyl, (C 3 -C 6) cycloalkyl (Ci-C4) - alkoxycarbonyl (Ci-C4) alkyl, aryl (Ci-C4) alkoxycarbonyl (Ci-C4) alkyl, heteroaryl (Ci-C4) alkoxycarbonyl ( Ci-C 4) alkyl, (Ci-C4) - alkylaminocarbonyl (Ci-C 4) alkyl, aminocarbonyl (Ci-C 4) alkyl, bis (Ci-C 4) -alkylaminocarbonyl- (C C4) alkyl, (C3-C6) - cycloalkylaminocarbonyl (Ci-C4) alkyl, aryl (Ci-C4) - alkylaminocarbonyl (Ci-C4) alkyl, Heteroarylaminocarbonyl- (Ci C 4) - alkyl, cyano (Ci-C4) alkylaminocarbonyl (Ci-C4) alkyl, (C1-C4) - Haloalkylaminocarbonyl- (Ci-C4) alkyl, (C2-C4) alkynyl (Ci C4) - alkylaminocarbonyl (Ci-C4) alkyl, amino (Ci-C4) alkyl, (C1-C4) - alkyl amino (Ci-C4) alkyl, (C2-C4) -Alkenylamino- (Ci C4) alkyl,
    Arylamino-(Ci-C4)-alkyl, Bis-(Ci-C4)-alkylamino-(Ci-C4)-alkyl, Bis- (C3-C6)-cycloalkylamino-(Ci-C4)-alkyl, Aryl-(Ci-C4)-alkylamino-(Ci-C4)- alkyl, Tris-Aryl-(Ci-C4)-alkylamino-(Ci-C4)-alkyl, (C 3 -C 6 )- Cycloalkylamino-(Ci-C4)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C4)-alkylamino- (Ci-C4)-alkyl, (Ci-C4)-Haloalkylamino-(Ci-C4)-alkyl, (C1-C4)- Alkylcarbonylamino-(Ci-C4)-alkyl, (Ci-C4)-Cycloalkylcarbonylamino- (Ci-C4)-alkyl, Arylcarbonylamino-(Ci-C4)-alkyl, Arylamino (Ci-C4) alkyl, bis (Ci-C4) alkylamino (Ci-C4) alkyl, bis (C3-C6) cycloalkylamino (Ci-C4) alkyl, aryl (Ci C4) alkylamino (Ci-C4) - alkyl, Tris-aryl (Ci-C4) alkylamino (Ci-C4) alkyl, (C3-C6) - cycloalkylamino (Ci-C4) - alkyl, (C3-C6) cycloalkyl (Ci-C4) alkylamino (Ci-C4) alkyl, (Ci-C4) -Haloalkylamino- (Ci-C4) alkyl, (C1-C4) - alkylcarbonylamino (Ci-C4) alkyl, (Ci-C4) -Cycloalkylcarbonylamino- (Ci-C4) alkyl, arylcarbonylamino (Ci-C4) alkyl,
    Heteroarylcarbonylamino-(Ci-C4)-alkyl, (Ci-C4)-Alkoxycarbonylamino- (Ci-C4)-alkyl, (C2-C4)-Alkenyloxycarbonylamino-(Ci-C4)-alkyl, Aryl- (Ci-C4)-alkoxycarbonylamino-(Ci-C4)-alkyl, Aryl-(Ci-C4)- alkoxycarbonyl[N-(Ci-C4)-alkyl]amino-(Ci-C4)-alkyl, Heteroaryl-(Ci-C4)- alkoxycarbonylamino-(Ci-C4)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C4)- alkoxycarbonylamino-(Ci-C4)-alkyl, (C3-C6)-Cycloalkoxycarbonylamino- (Ci-C4)-alkyl, Aminocarbonylamino-(Ci-C4)-alkyl, Arylsulfonylamino- (Ci-C4)-alkyl, Heteroarylsulfonylamino-(Ci-C4)-alkyl, (C1-C4)- Alkylsulfonylamino-(Ci-C4)-alkyl, (C3-C6)-Cycloalkylsulfonylamino- (Ci-C4)-alkyl, Aminoiminoamino-(Ci-C4)-alkyl, Heteroarylcarbonylamino- (Ci-C4) alkyl, (Ci-C4) alkoxycarbonylamino (Ci-C4) alkyl, (C2-C4) -Alkenyloxycarbonylamino- (Ci-C4) alkyl, aryl (Ci-C4) - alkoxycarbonylamino (Ci-C4) alkyl, aryl (Ci-C4) - alkoxycarbonyl [N- (Ci-C4) alkyl] amino (Ci-C4) alkyl, heteroaryl (Ci-C4) - alkoxycarbonylamino (Ci-C4) alkyl, (C3-C6) cycloalkyl (Ci-C4) - alkoxycarbonylamino (Ci-C4) alkyl, (C3-C6) -Cycloalkoxycarbonylamino- (Ci-C4) alkyl, aminocarbonylamino (Ci-C4) alkyl, arylsulfonylamino (Ci-C4) alkyl, Heteroarylsulfonylamino- (Ci-C4) alkyl, (C1-C4) - alkylsulfonylamino (Ci-C4) alkyl, (C3-C6) - Cycloalkylsulfonylamino- (Ci-C4) alkyl, Aminoiminoamino- (Ci-C4) alkyl,
    Arylsulfonylaminoiminoamino-(Ci-C4)-alkyl, (C1-C4)- Alkylaminoiminoamino-(Ci-C4)-alkyl steht, für Wasserstoff, Halogen, (Ci-C 4 )-Alkyl, (Ci-C 4 )-Alkoxy, (C1-C4)- Arylsulfonylaminoiminoamino- (Ci-C4) alkyl, (C1-C4) - Alkylaminoiminoamino- (Ci-C4) alkyl, hydrogen, halogen, (Ci-C4) alkyl, (Ci-C4) alkoxy, (C1-C4) -
    Alkoxycarbonyloxy, (C2-C4)-Alkenyl, (C2-C4)-Haloalkenyl, (C2-C4)- Alkenyl-(Ci-C 4 )-alkyl, (C2-C 4 )-Alkinyl, (C 2 -C4)-Alkinyl-(Ci-C4)-alkyl, Aryl- (Ci-C 4 )-alkyl, Bisaryl-(Ci-C 4 )-alkyl, Aryl-(Ci-C4)-alkoxyaryl-(Ci-C4)- alkyl, Aryloxyaryl-(Ci-C 4 )-alkyl, (Ci-C4)-Alkoxyaryl-(Ci-C4)-alkyl, Heteroaryl-(Ci-C 4 )-alkyl, Heterocyclyl-(Ci-C4)-alkyl, N-(Ci-C 4 )- Alkoxycarbonyloxy, (C2-C4) -alkenyl, (C2-C4) haloalkenyl, (C2-C4) - alkenyl (Ci-C4) alkyl, (C2-C4) alkynyl, (C 2 -C 4) alkynyl (Ci-C4) alkyl, aryl (Ci-C4) alkyl, bisaryl (Ci-C4) alkyl, aryl (Ci-C4) -alkoxyaryl- (Ci-C4) - alkyl , Aryloxyaryl- (Ci-C4) alkyl, (Ci-C4) -Alkoxyaryl- (Ci-C4) alkyl, heteroaryl (Ci-C4) alkyl, heterocyclyl (Ci-C4) alkyl, N - (Ci-C4) -
    Alkylheterocyclyl-(Ci-C4)-alkyl, N-[(Ci-C4)-Alkoxycarbonyl]heterocyclyl- (Ci-C4)-alkyl, N-(Aryl-(Ci-C4)-alkoxycarbonyl)heterocyclyl-(Ci-C4)-alkyl, N-(Arylcarbonyl)heterocyclyl-(Ci-C 4 )-alkyl, N-[(Ci-C 4 )- Alkylcarbonyl]heterocyclyl-(Ci-C 4 )-alkyl, N-[(C 3 -C 6 )- Cycloalkylcarbonyl]heterocyclyl-(Ci-C 4 )-alkyl, Cyano-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, (C 3 -C 6 )-Cycloalkyl, (C 3 -C 6 )-Halocycloalkyl, (C 4 -C 6 )- Cycloalkenyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkenyl- (Ci-C 4 )-alkyl, Hydroxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkoxy-(Ci-C 4 )-alkyl, Aryloxy-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )- alkoxy-(Ci-C 4 )-alkyl, Heteroaryl-(Ci-C 4 )-alkoxy-(Ci-C 4 )-alkyl, (C 3 -C 6 )- Cycloalkoxy-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C 4 )-alkoxy-(Ci-C 4 )- alkyl, (Ci-C 4 )-Alkylcarbonyloxy-(Ci-C 4 )-alkyl, Arylcarbonyloxy-(Ci-C 4 )- alkyl, Heteroarylcarbonyloxy-(Ci-C 4 )-alkyl, (C 3 -C6)- Cycloalkylcarbonyloxy-(Ci-C 4 )-alkyl, Arylsulfonyloxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylsulfonyloxy-(Ci-C 4 )-alkyl, Hydrothio-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylthio-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkylthio-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )- alkylthio-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkylthio-(Ci-C 4 )-alkyl, Arylthio- (Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylsulfinyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylsulfonyl- (Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkylsulfinyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Haloalkylsulfonyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkylsulfinyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkylsulfonyl-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkylsulfinyl- (Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkylsulfonyl-(Ci-C 4 )-alkyl, Aryl, Heteroaryl, Heterocyclyl, N-[(Ci-C 4 )-Alkyl]heterocyclyl, N-[(Ci-C 4 )- Alkoxycarbonyl]heterocyclyl, N-[Aryl-(Ci-C 4 )- alkoxycarbonyl]heterocyclyl, N-(Arylcarbonyl)heterocyclyl, N-[(Ci-C 4 )- Alkylcarbonyl]heterocyclyl, N-[(Ci-C 4 )-Cycloalkylcarbonyl]heterocyclyl, Hydroxycarbonyl, (Ci-C 4 )-Alkoxycarbonyl, (C 3 -C6)- Cycloalkoxycarbonyl, (C 3 -C6)-Cycloalkyl-(Ci-C 4 )-alkoxycarbonyl, Aryl- (Ci-C 4 )-alkoxycarbonyl, Heteroaryl-(Ci-C 4 )-alkoxycarbonyl, (Ci-C 4 )- Alkylaminocarbonyl, Aminocarbonyl, Bis-(Ci-C 4 )-alkylaminocarbonyl, (C 3 -C6)-Cycloalkylaminocarbonyl, Aryl-(Ci-C 4 )-alkylaminocarbonyl, Heteroarylaminocarbonyl, Cyano-(Ci-C 4 )-alkylaminocarbonyl, (Ci-C 4 )- Haloalkylaminocarbonyl, (C2-C 4 )-Alkinyl-(Ci-C 4 )-alkylaminocarbonyl, Hydroxycarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxycarbonyl-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkoxycarbonyl-(Ci-C4)-alkyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C 4 )- alkoxycarbonyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkoxycarbonyl-(Ci-C 4 )-alkyl, Heteroaryl-(Ci-C 4 )-alkoxycarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylaminocarbonyl-(Ci-C 4 )-alkyl, Aminocarbonyl-(Ci-C 4 )-alkyl, Bis- (Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, (C3-C6)- Cycloalkylaminocarbonyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )- alkylaminocarbonyl-(Ci-C 4 )-alkyl, Heteroarylaminocarbonyl-(Ci-C 4 )- alkyl, Cyano-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Haloalkylaminocarbonyl-(Ci-C 4 )-alkyl, (C2-C 4 )-Alkinyl-(Ci-C 4 )- alkylaminocarbonyl-(Ci-C 4 )-alkyl, Amino-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylamino-(Ci-C 4 )-alkyl, (C2-C 4 )-Alkenylamino-(Ci-C 4 )-alkyl, Alkylheterocyclyl- (Ci-C4) alkyl, N - [(Ci-C4) alkoxycarbonyl] heterocyclyl (Ci-C4) alkyl, N- (aryl (Ci-C4) alkoxycarbonyl) heterocyclyl (Ci-C4 ) alkyl, N- (arylcarbonyl) heterocyclyl- (Ci-C 4) alkyl, N - [(Ci-C4) - alkylcarbonyl] heterocyclyl (Ci-C 4) alkyl, N - [(C 3 - C 6) - cycloalkylcarbonyl] heterocyclyl (Ci-C 4) alkyl, cyano (Ci-C 4) alkyl, (Ci-C 4) -haloalkyl, (C 3 -C 6) -cycloalkyl, (C 3 -C 6) halocycloalkyl, (C 4 -C 6) - cycloalkenyl, (C 3 -C 6) cycloalkyl (Ci-C 4) alkyl, (C 3 -C 6) cycloalkenyl (C 4) alkyl, hydroxy (Ci-C 4) alkyl, (Ci-C 4) alkoxy (Ci-C 4) alkyl, (Ci-C 4) haloalkoxy (Ci-C 4) - alkyl, aryloxy (Ci-C4) alkyl, aryl (Ci-C4) - alkoxy (Ci-C4) alkyl, heteroaryl (Ci-C4) alkoxy (Ci-C4) alkyl, (C 3 -C 6) - cycloalkoxy (Ci-C 4) alkyl, (C 3 -C 6) cycloalkyl (Ci-C 4) alkoxy (Ci-C 4) - alkyl, (Ci-C4) alkylcarbonyloxy (Ci-C4) alkyl, arylcarbonyloxy (Ci-C4) - alkyl, Heteroarylcarbonyloxy- (Ci-C4) alkyl, (C3-C6) - Cycloalkylcarbonyloxy- ( Ci-C 4) alkyl, arylsulfonyloxy (Ci-C 4) alkyl, (Ci-C 4) alkylsulfonyloxy (Ci-C 4) alkyl, Hydrothio- (Ci-C 4) alkyl, (C -C 4) - alkylthio (Ci-C4) alkyl, (Ci-C4) -Haloalkylthio- (Ci-C4) alkyl, aryl (Ci-C 4) - alkylthio (Ci-C 4 ) alkyl, (C 3 -C 6) cycloalkylthio (Ci-C 4) alkyl, arylthio (Ci-C 4) alkyl, (Ci-C 4) alkylsulfinyl (Ci-C 4) - alkyl, (Ci-C4) alkylsulphonyl (Ci-C4) alkyl, (Ci-C4) -Haloalkylsulfinyl- (Ci-C4) alkyl, (Ci-C4) - Haloalkylsulfonyl- (Ci C 4) alkyl, aryl (Ci-C 4) alkylsulfinyl (Ci-C 4) alkyl, aryl (Ci-C 4) alkylsulfonyl (Ci-C 4) alkyl, (C 3 - C 6) -Cycloalkylsulfinyl- (Ci-C 4) alkyl, (C 3 -C 6) -Cycloalkylsulfonyl- (Ci-C 4) alkyl, aryl, heteroaryl, heterocyclyl, N - [(Ci-C 4) - alkyl] heterocyclyl, N - [(Ci-C4) - alkoxycarbonyl] heterocyclyl, N- [aryl (Ci-C4) - alkoxycarbonyl] heterocyclyl, N- (arylcarbonyl) heterocyclyl, N - [(Ci-C4) - alkylcarbonyl] heterocyclyl, N - [(Ci-C4) -cycloalkylcarbonyl] heterocyclyl, hydroxycarbonyl, (Ci-C4) -alkoxycarbonyl, (C 3 -C 6) - cycloalkoxycarbonyl, (C 3 -C 6) cycloalkyl- (Ci -C 4) alkoxycarbonyl, aryl (Ci-C4) alkoxycarbonyl, heteroaryl (Ci-C4) -alkoxycarbonyl, (Ci-C4) - alkylaminocarbonyl, aminocarbonyl, bis (Ci-C4) alkylaminocarbonyl , (C3-C6) cycloalkylaminocarbonyl, aryl (Ci-C4) alkylaminocarbonyl, heteroarylaminocarbonyl, cyano (Ci-C4) alkylaminocarbonyl, (Ci-C4) - Haloalkylaminocarbonyl, (C2-C4) - alkynyl (Ci-C4) alkylaminocarbonyl, hydroxycarbonyl (Ci-C 4) alkyl, (Ci-C 4) alkoxycarbonyl (Ci-C 4) alkyl, (C 3 -C 6) -Cycloalkoxycarbonyl- (Ci-C4) alkyl, (C3-C6) cycloalkyl (Ci-C4) - alkoxycarbonyl (Ci-C4) alkyl, aryl (Ci-C4) alkoxycarbonyl (Ci C 4) alkyl, heteroaryl (Ci-C 4) alkoxycarbonyl (Ci-C 4) alkyl, (Ci-C4) - alkylaminocarbonyl (Ci-C 4) alkyl, aminocarbonyl (Ci-C 4) alkyl, bis (Ci-C4) alkylaminocarbonyl (Ci-C4) alkyl, (C3-C6) - cycloalkylaminocarbonyl (Ci-C4) alkyl, aryl (Ci-C4) - alkylaminocarbonyl (Ci-C4) alkyl, Heteroarylaminocarbonyl- (Ci-C4) - alkyl, cyano (Ci-C4) alkylaminocarbonyl (Ci-C4) alkyl, (Ci-C4) - Haloalkylaminocarbonyl- (Ci-C4) alkyl, (C2-C4) alkynyl (Ci-C4) - alkylaminocarbonyl (Ci-C4) alkyl, amino (Ci-C4) alkyl, ( Ci-C4) - alkyl amino (Ci-C4) alkyl, (C2-C4) -Alkenylamino- (Ci-C4) alkyl,
    Arylamino-(Ci-C 4 )-alkyl, Bis-(Ci-C 4 )-alkylamino-(Ci-C 4 )-alkyl, Bis- (C3-C6)-cycloalkylamino-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkylamino-(Ci-C 4 )- alkyl, Tris-Aryl-(Ci-C 4 )-alkylamino-(Ci-C 4 )-alkyl, (C 3 -C 6 )- Cycloalkylamino-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkylamino- (Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylcarbonylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Cycloalkylcarbonylamino- (Ci-C 4 )-alkyl, Arylcarbonylamino-(Ci-C 4 )-alkyl, Arylamino (Ci-C4) alkyl, bis (Ci-C4) alkylamino (Ci-C4) alkyl, bis (C3-C6) cycloalkylamino (Ci-C4) alkyl, aryl (Ci-C 4) alkylamino (C 4) - alkyl, Tris-aryl (Ci-C 4) alkylamino (C 4) alkyl, (C3-C6) - cycloalkylamino (Ci-C4) alkyl, (C3-C6) cycloalkyl (Ci-C4) alkylamino (Ci-C4) alkyl, (Ci-C4) -Haloalkylamino- (C 4) alkyl, (Ci-C4) - alkylcarbonylamino (Ci-C 4) alkyl, (Ci-C 4) -Cycloalkylcarbonylamino- (Ci-C 4) alkyl, arylcarbonylamino (Ci-C 4) - alkyl,
    Heteroarylcarbonylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxycarbonylamino- (Ci-C 4 )-alkyl, (C2-C 4 )-Alkenyloxycarbonylamino-(Ci-C 4 )-alkyl, Aryl- (Ci-C 4 )-alkoxycarbonylamino-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )- alkoxycarbonyl[N-(Ci-C 4 )-alkyl]amino-(Ci-C 4 )-alkyl, Heteroaryl-(Ci-C 4 )- alkoxycarbonylamino-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )- alkoxycarbonylamino-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkoxycarbonylamino- (Ci-C 4 )-alkyl, Aminocarbonylamino-(Ci-C 4 )-alkyl, Arylsulfonylamino- (Ci-C 4 )-alkyl, Heteroarylsulfonylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylsulfonylamino-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkylsulfonylamino- (Ci-C 4 )-alkyl, Aminoiminoamino-(Ci-C 4 )-alkyl, Heteroarylcarbonylamino- (Ci-C4) alkyl, (Ci-C4) alkoxycarbonylamino (Ci-C4) alkyl, (C2-C4) -Alkenyloxycarbonylamino- (Ci-C4) alkyl, aryl ( Ci-C4) alkoxycarbonylamino (Ci-C4) alkyl, aryl (Ci-C4) - alkoxycarbonyl [N- (Ci-C4) alkyl] amino (Ci-C4) alkyl, heteroaryl- (Ci-C4) - alkoxycarbonylamino (Ci-C4) alkyl, (C3-C6) cycloalkyl (Ci-C4) - alkoxycarbonylamino (Ci-C4) alkyl, (C3-C6 ) -Cycloalkoxycarbonylamino- (Ci-C 4) alkyl, aminocarbonylamino (Ci-C 4) alkyl, arylsulfonylamino (Ci-C 4) alkyl, Heteroarylsulfonylamino- (Ci-C 4) alkyl, (Ci-C 4) - alkylsulfonylamino (Ci-C4) alkyl, (C3-C6) -Cycloalkylsulfonylamino- (Ci-C4) alkyl, Aminoiminoamino- (Ci-C4) alkyl,
    Arylsulfonylaminoiminoamino-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylaminoiminoamino-(Ci-C 4 )-alkyl steht, R 8 unabhängig voneinander für H, (Ci-C 4 )-Alkyl, (C 2 -C 4 )-Alkenyl- (Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkinyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkyl, (C 3 -C 6 )- Cycloalkyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkyl, Heterocyclyl, Heterocyclyl- (Ci-C 4 )-alkyl, Amino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, Arylsulfonylaminoiminoamino- (Ci-C 4) alkyl, (Ci-C 4) - Alkylaminoiminoamino- (Ci-C 4) -alkyl, R 8 independently of one another H, (Ci-C 4) -alkyl, (C 2 - C 4) alkenyl, (Ci-C 4) alkyl, (C 2 -C 4) alkynyl (Ci-C 4) alkyl, aryl (Ci-C 4) alkyl, (C 3 -C 6) - cycloalkyl, (C3-C6) cycloalkyl (Ci-C4) alkyl, heterocyclyl, heterocyclyl (Ci-C4) alkyl, amino (Ci-C4) alkyl, (Ci-C 4) alkoxy (Ci-C 4) alkyl,
    (Ci-C 4 )-Alkylthio-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, (Ci-C 4 )-Alkylamino- (Ci-C 4 )-alkyl, Bis-(Ci-C 4 )-alkylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylcarbonylamino-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkylcarbonylamino- (Ci-C 4 )-alkyl, Arylcarbonylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkoxycarbonylamino-(Ci-C6)-alkyl, Aryl-(Ci-C 4 )-alkoxycarbonylamino- (Ci-C 4 )-alkyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkoxycarbonylamino-(Ci-C 4 )- alkyl, Aminocarbonylamino-(Ci-C 4 )-alkyl, Aminoiminoamino-(Ci-C 4 )- alkyl, Arylsulfonylaminoiminoamino-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylaminoiminoamino-(Ci-C 4 )-alkyl stehen, für H, (Ci-C 4 )-Alkyl, (C 2 -C 4 )-Alkenyl-(Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkinyl, (Ci-C4) alkylthio (Ci-C4) alkyl, (Ci-C4) -haloalkyl, (Ci-C4) -alkylamino (Ci-C4) alkyl, bis (Ci C 4) alkylamino (C 4) alkyl, (Ci-C4) - alkylcarbonylamino (Ci-C4) alkyl, (C3-C6) -Cycloalkylcarbonylamino- (Ci-C4) alkyl, arylcarbonylamino (Ci-C4) alkyl, (Ci-C4) - alkoxycarbonylamino (Ci-C6) alkyl, aryl (Ci-C4) alkoxycarbonylamino (Ci-C4) alkyl, (C3 C6) cycloalkyl- (Ci-C4) alkoxycarbonylamino (Ci-C4) - alkyl, aminocarbonylamino (Ci-C4) alkyl, Aminoiminoamino- (Ci-C4) - alkyl, Arylsulfonylaminoiminoamino- (Ci C4) alkyl, (Ci-C4) - Alkylaminoiminoamino- (Ci-C4) alkyl, H, (Ci-C4) alkyl, (C2-C4) -alkenyl (Ci -C 4) alkyl, (C 2 -C 4) alkynyl,
    (Ci-C 4 )-Alkylcarbonyl, (C3-C6)-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl, (Ci-C 4 )-Alkoxycarbonyl, Aryl-(Ci-C 4 )- alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl- (Ci-C 4 )-alkoxycarbonyl, (Ci-C 4 )-Alkylsulfonyl, (C 3 -C 6 )- Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C 4 )-Alkoxycarbonylcarbonyl, Aryl- (Ci-C 4 )-alkoxycarbonylcarbonyl, (Ci-C 4 )-Alkylaminothiocarbonyl, (Ci-C4) alkylcarbonyl, (C3-C6) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl, (Ci-C4) alkoxycarbonyl, aryl (Ci-C4) - alkoxy, (C3-C6) cycloalkoxycarbonyl, ( C3-C6) cycloalkyl (Ci-C4) -alkoxycarbonyl, (Ci-C4) alkylsulphonyl, (C3-C6) - cycloalkylsulphonyl, arylsulphonyl, (Ci-C4) -Alkoxycarbonylcarbonyl, aryl (Ci C4) -alkoxycarbonylcarbonyl, (Ci-C4) -Alkylaminothiocarbonyl,
    (Ci-C 4 )-Alkylaminocarbonyl, Aryl-(Ci-C 4 )-alkyl, Hetaroaryl-(Ci-C 4 )-alkyl, Cyano-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, (C3-C 6 )-Cycloalkyl, (C 3 -C 6 )- Cycloalkyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )- Haloalkoxy-(Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkinyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkoxycarbonyl-(Ci-C 4 )-alkyl, Aminocarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylaminocarbonyl-(Ci-C 4 )-alkyl, Bis-(Ci-C 4 )-alkylaminocarbonyl- (Ci-C 4 )-alkyl steht, (Ci-C4) alkylaminocarbonyl, aryl (Ci-C4) alkyl, Hetaroaryl- (Ci-C4) alkyl, cyano (Ci-C4) alkyl, (Ci-C4) -haloalkyl , (C3-C 6) -cycloalkyl, (C 3 -C 6) - cycloalkyl, (Ci-C 4) alkyl, (Ci-C 4) alkoxy (Ci-C 4) alkyl, (Ci- C 4) - haloalkoxy (Ci-C4) alkyl, (C2-C4) alkynyl (Ci-C4) alkyl, (Ci-C4) - alkoxycarbonyl (Ci-C4) - alkyl, aminocarbonyl (Ci-C4) alkyl, (Ci-C4) - alkylaminocarbonyl (Ci-C4) alkyl, bis (Ci-C4) alkylaminocarbonyl (Ci-C4) alkyl stands,
    im Falle der Gruppierung Q-21 ausschließlich für H oder Methyl steht, für (C 2 -C 4 )-Alkyl, (C 2 -C 4 )-Alkenyl-(Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkinyl, (Ci-C 4 )- Alkylcarbonyl, (C3-C6)-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl, (Ci-C 4 )-Alkoxycarbonyl, Aryl-(Ci-C 4 )- alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl- (Ci-C 4 )-alkoxycarbonyl, (Ci-C 4 )-Alkylsulfonyl, (C 3 -C 6 )- Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C 4 )-Alkoxycarbonylcarbonyl, Aryl- (Ci-C 4 )-alkoxycarbonylcarbonyl, (Ci-C 4 )-Alkylaminothiocarbonyl, in the case of the group Q-21 is available exclusively for H or methyl, (C 2 -C 4) alkyl, (C 2 -C 4) alkenyl, (Ci-C 4) alkyl, (C 2 -C 4 ) -alkynyl, (Ci-C4) - alkylcarbonyl, (C3-C6) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl, (Ci-C4) alkoxycarbonyl, aryl (Ci-C4) - alkoxy, (C3-C6) cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C4) -alkoxycarbonyl, (Ci-C4) alkylsulphonyl, (C3-C6) - cycloalkylsulphonyl, arylsulphonyl, (Ci-C4) -Alkoxycarbonylcarbonyl, aryl (Ci-C4) -alkoxycarbonylcarbonyl, (Ci-C4) -Alkylaminothiocarbonyl,
    (Ci-C 4 )-Alkylaminocarbonyl, Aryl-(Ci-C 4 )-alkyl, Hetaroaryl-(Ci-C 4 )-alkyl, Cyano-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, (C 3 -C 6 )-Cycloalkyl, (C 3 -C 6 )- Cycloalkyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )- Haloalkoxy-(Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkinyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkoxycarbonyl-(Ci-C 4 )-alkyl, Aminocarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylaminocarbonyl-(Ci-C 4 )-alkyl, Bis-(Ci-C 4 )-alkylaminocarbonyl- (Ci-C 4 )-alkyl steht, (Ci-C4) alkylaminocarbonyl, aryl (Ci-C4) alkyl, Hetaroaryl- (Ci-C4) alkyl, cyano (Ci-C4) alkyl, (Ci-C4) -haloalkyl , (C 3 -C 6) -cycloalkyl, (C 3 -C 6) - cycloalkyl, (Ci-C 4) alkyl, (Ci-C 4) alkoxy (Ci-C 4) alkyl, (C C4) - haloalkoxy (Ci-C4) alkyl, (C2-C4) alkynyl (Ci-C4) alkyl, (Ci-C4) - alkoxycarbonyl (Ci-C4) alkyl, aminocarbonyl (Ci-C4) alkyl, (Ci-C4) - alkylaminocarbonyl (Ci-C4) alkyl, bis (Ci-C4) alkylaminocarbonyl (Ci-C4) - alkyl,
    R 43 für H oder Methyl steht, R 43 is H or methyl,
    R 44 für Wasserstoff, (Ci-C 4 )-Alkyl, (C 2 -C 4 )-Alkenyl-(Ci-C 4 )-alkyl, (C 2 -C 4 )- Alkinyl, (Ci-C 4 )-Alkylcarbonyl, (C3-C6)-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl, (Ci-C 4 )-Alkoxycarbonyl, Aryl-(Ci-C 4 )- alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl- (Ci-C 4 )-alkoxycarbonyl, (Ci-C 4 )-Alkylsulfonyl, (C 3 -C 6 )- Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C 4 )-Alkoxycarbonylcarbonyl, Aryl- (Ci-C 4 )-alkoxycarbonylcarbonyl, (Ci-C 4 )-Alkylaminothiocarbonyl, R 44 is hydrogen, (Ci-C 4) -alkyl, (C 2 -C 4) alkenyl (Ci-C 4) alkyl, (C 2 -C 4) - alkynyl, (Ci-C 4) - alkylcarbonyl, (C3-C6) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl, (Ci-C4) alkoxycarbonyl, aryl (Ci-C4) - alkoxy, (C3-C6) cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C4) -alkoxycarbonyl, (Ci-C4) alkylsulphonyl, (C3-C6) - cycloalkylsulphonyl, arylsulphonyl, (Ci-C4) -Alkoxycarbonylcarbonyl, aryl (Ci-C4) -alkoxycarbonylcarbonyl, (Ci-C4) -Alkylaminothiocarbonyl,
    (Ci-C 4 )-Alkylaminocarbonyl, Aryl-(Ci-C 4 )-alkyl, Hetaroaryl-(Ci-C 4 )-alkyl, Cyano-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, (C 3 -C 6 )-Cycloalkyl, (C 3 -C 6 )- Cycloalkyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )- Haloalkoxy-(Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkinyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkoxycarbonyl-(Ci-C 4 )-alkyl, Aminocarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylaminocarbonyl-(Ci-C 4 )-alkyl, Bis-(Ci-C 4 )-alkylaminocarbonyl- (Ci-C 4 )-alkyl steht, 51 und R 71 unabhängig voneinander für Wasserstoff und Methyl stehen, R 53 für Methyl steht, (Ci-C4) alkylaminocarbonyl, aryl (Ci-C4) alkyl, Hetaroaryl- (Ci-C4) alkyl, cyano (Ci-C4) alkyl, (Ci-C4) -haloalkyl , (C 3 -C 6) -cycloalkyl, (C 3 -C 6) - cycloalkyl, (Ci-C 4) alkyl, (Ci-C 4) alkoxy (Ci-C 4) alkyl, (C C4) - haloalkoxy (Ci-C4) alkyl, (C2-C4) alkynyl (Ci-C4) alkyl, (Ci-C4) - alkoxycarbonyl (Ci-C4) alkyl, aminocarbonyl (Ci-C4) alkyl, (Ci-C4) - alkylaminocarbonyl (Ci-C4) alkyl, bis (Ci-C4) alkylaminocarbonyl (Ci-C4) - alkyl; 51 and R 71 independently represent hydrogen and methyl, R 53 is methyl,
    R 61 und R 81 unabhängig voneinander für Wasserstoff und Methyl stehen, R 63 für H, Methyl steht, R 61 and R 81 independently represent hydrogen and methyl, R 63 is H, methyl,
    R 54 , R 64 , R 74 , R 84 unabhängig voneinander für Wasserstoff, Methyl stehen, wobei mindestens eine der Gruppen R 54 , R 64 , R 74 , R 84 für Methyl stehen muß, R 54, R 64, R 74, R 84 are independently hydrogen, methyl, where at least one of R 54, R 64, R 74, R 84 must be methyl,
    V für Hydroxycarbonyl, (Ci-C 4 )-Alkoxycarbonyl, (C3-C6)- Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C 4 )-alkoxycarbonyl, Aminocarbonyl, (Ci-C 4 )- Alkylaminocarbonyl, Bis-(Ci-C 4 )-alkylaminocarbonyl, (Ci-C 4 )- Alkyl[(Ci-C 4 )-Alkoxy]aminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Aryl-(Ci-C 4 )-alkylaminocarbonyl, Heteroaryl-(Ci-C 4 )- alkylaminocarbonyl, Cyano-(Ci-C 4 )-alkylaminocarbonyl, (Ci-C 4 )- Haloalkylaminocarbonyl, (C2-C 4 )-Alkinyl-(Ci-C 4 )-alkylaminocarbonyl, (Ci-C 4 )-Alkoxycarbonyl-(Ci-C 4 )-alkylaminocarbonyl, Hydroxycarbonyl- (Ci-C 4 )-alkylaminocarbonyl, Aminocarbonyl-(Ci-C 4 )- alkylaminocarbonyl, (Ci-C 4 )-Alkylaminocarbonyl-(Ci-C 4 )- alkylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl-(Ci-C 4 )- alkylaminocarbonyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkylaminocarbonyl steht, m für O, 1 , 2, 3, 4, 5 steht, p für 1 , 2, 3, 4 steht, V hydroxycarbonyl, (Ci-C4) alkoxycarbonyl, (C3-C6) - cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C4) alkoxycarbonyl, aryloxycarbonyl, aryl (Ci-C4) alkoxycarbonyl , aminocarbonyl, (Ci-C4) - alkylaminocarbonyl, bis (Ci-C4) alkylaminocarbonyl, (Ci-C4) - alkyl [(Ci-C4) alkoxy] aminocarbonyl, (C3-C6) cycloalkylaminocarbonyl , aryl (Ci-C4) alkylaminocarbonyl, heteroaryl (Ci-C4) - alkylaminocarbonyl, cyano (Ci-C4) alkylaminocarbonyl, (Ci-C4) - Haloalkylaminocarbonyl, (C2-C4) - alkynyl (Ci-C4) alkylaminocarbonyl, (Ci-C4) alkoxycarbonyl (Ci-C4) alkylaminocarbonyl, hydroxycarbonyl (Ci-C4) alkylaminocarbonyl, aminocarbonyl (Ci-C4) - alkylaminocarbonyl , (Ci-C4) alkylaminocarbonyl (Ci-C4) - alkylaminocarbonyl, (C3-C6) -Cycloalkylaminocarbonyl- (Ci-C4) - alkylaminocarbonyl, (C3-C6) cycloalkyl (Ci-C4) alkylaminocarbonyl, m is O, 1, 2, 3, 4, 5, p is 1, 2, 3, 4 is,
    Y für Cyano, Cyano-(Ci-C 4 )-alkyl, Hydroxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxy- (Ci-C 4 )-alkyl, Hydroxycarbonyl, (Ci-C 4 )-Alkoxycarbonyl, (C3-C6)- Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C 4 )-alkoxycarbonyl, Aminocarbonyl, (Ci-C 4 )- Alkylaminocarbonyl, Bis-(Ci-C 4 )-alkylaminocarbonyl, (Ci-C 4 )- Alkyl[(Ci-C 4 )-Alkoxy]aminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Aryl-(Ci-C 4 )-alkylaminocarbonyl, Heteroaryl-(Ci-C 4 )- alkylaminocarbonyl, Cyano-(Ci-C 4 )-alkylaminocarbonyl, (Ci-C 4 )- Haloalkylaminocarbonyl, (C2-C 4 )-Alkinyl-(Ci-C 4 )-alkylaminocarbonyl, (Ci-C 4 )-Alkoxycarbonylaminocarbonyl, Aryl-(Ci-C 4 )- alkoxycarbonylaminocarbonyl, Hydroxycarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkoxycarbonyl-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkoxycarbonyl-(Ci-C 4 )- alkyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C 4 )-alkoxycarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylaminocarbonyl-(Ci-C 4 )-alkyl, Aminocarbonyl-(Ci-C 4 )-alkyl, Bis- (Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, (C3-C6)- Cycloalkylaminocarbonyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )- alkylaminocarbonyl-(Ci-C 4 )-alkyl, Heteroaryl-(Ci-C 4 )- alkylaminocarbonyl-(Ci-C 4 )-alkyl, Cyano-(Ci-C 4 )-alkylaminocarbonyl- (Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkylaminocarbonyl-(Ci-C 4 )-alkyl, (C 2 -C 4 )- Alkinyl-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkyl- (Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkoxycarbonylaminocarbonyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )- alkoxycarbonylaminocarbonyl-(Ci-C 4 )-alkyl, Y is cyano, cyano (Ci-C 4) alkyl, hydroxy (Ci-C 4) alkyl, (Ci-C 4) alkoxy (Ci-C 4) alkyl, hydroxycarbonyl, (Ci-C 4) -alkoxycarbonyl, (C3-C6) - cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C4) alkoxycarbonyl, aryloxycarbonyl, aryl (Ci-C4) alkoxycarbonyl, aminocarbonyl, (Ci-C 4 ) - alkylaminocarbonyl, bis (Ci-C4) alkylaminocarbonyl, (Ci-C4) - alkyl [(Ci-C4) alkoxy] aminocarbonyl, (C3-C6) cycloalkylaminocarbonyl, aryl (Ci-C 4 ) alkylaminocarbonyl, heteroaryl (Ci-C4) - alkylaminocarbonyl, cyano (Ci-C4) alkylaminocarbonyl, (Ci-C4) - Haloalkylaminocarbonyl, (C2-C4) alkynyl (Ci-C4) alkylaminocarbonyl, (Ci-C4) -Alkoxycarbonylaminocarbonyl, aryl (Ci-C4) - alkoxycarbonylaminocarbonyl, hydroxycarbonyl (Ci-C4) alkyl, (Ci-C4) - alkoxycarbonyl (Ci-C4) - alkyl, (C3-C6) -Cycloalkoxycarbonyl- (Ci-C4) - alkyl, (C3-C6) cycloalkyl (Ci-C4) alkoxycarbonyl (Ci-C4) alkyl, (Ci C 4) - alkylaminocarbonyl (Ci-C4) alkyl, aminocarbonyl (Ci-C4) alkyl, bis (Ci-C4) alkylaminocarbonyl (Ci-C4) alkyl, (C3-C6 ) - cycloalkylaminocarbonyl (Ci-C4) alkyl, aryl (Ci-C4) - alkylaminocarbonyl (Ci-C4) alkyl, heteroaryl (Ci-C4) - alkylaminocarbonyl (Ci-C4) alkyl, cyano- (Ci-C4) -alkylaminocarbonyl- (Ci-C 4) alkyl, (Ci-C 4) -Haloalkylaminocarbonyl- (Ci-C 4) alkyl, (C 2 -C 4) - alkynyl - (Ci-C4) alkylaminocarbonyl (Ci-C4) alkyl, (C3-C6) cycloalkyl (Ci-C4) alkylaminocarbonyl (Ci-C4) alkyl, (Ci-C 4 ) - Alkoxycarbonylaminocarbonyl- (Ci-C4) alkyl, aryl (Ci-C4) - alkoxycarbonylaminocarbonyl- (Ci-C4) alkyl,
    (Ci-C 4 )-Alkoxycarbonyl-(Ci-C 4 )-alkylaminocarbonyl, Hydroxycarbonyl- (Ci-C 4 )-alkylaminocarbonyl, Aminocarbonyl-(Ci-C 4 )- alkylaminocarbonyl, (Ci-C 4 )-Alkylaminocarbonyl-(Ci-C 4 )- alkylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl-(Ci-C 4 )- alkylaminocarbonyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkylaminocarbonyl, (C3-C 6 )-Cycloalkyl-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, (C 2 -C 4 )- Alkenyloxycarbonyl, (C2-C 4 )-Alkenyloxycarbonyl-(Ci-C 4 )-alkyl, (C2-C 4 ) Alkenylaminocarbonyl, (C2-C 4 )-Alkenyl-(Ci-C 4 )-alkylaminocarbonyl, (C 2 -C 4 )-Alkenylaminocarbonyl-(Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkenyl-(Ci-C 4 )- alkylaminocarbonyl-(Ci-C 4 )-alkyl steht. (Ci-C4) alkoxycarbonyl (Ci-C4) alkylaminocarbonyl, hydroxycarbonyl (Ci-C4) alkylaminocarbonyl, aminocarbonyl (Ci-C4) - alkylaminocarbonyl, (Ci-C4) alkylaminocarbonyl ( Ci-C4) - alkylaminocarbonyl, (C3-C6) -Cycloalkylaminocarbonyl- (Ci-C4) - alkylaminocarbonyl, (C3-C6) cycloalkyl (Ci-C4) alkylaminocarbonyl, (C3-C6) cycloalkyl - (Ci-C4) alkylaminocarbonyl (Ci-C4) alkyl, (C2-C4) - alkenyloxycarbonyl, (C2-C4) -Alkenyloxycarbonyl- (Ci-C4) alkyl, (C2 C 4) alkenylaminocarbonyl, (C2-C4) -alkenyl (Ci-C4) alkylaminocarbonyl, (C2-C4) -Alkenylaminocarbonyl- (Ci-C4) alkyl, (C2-C4) - alkenyl (Ci-C4) - alkylaminocarbonyl (Ci-C4) alkyl. und Q weiterhin für eine der in der folgenden Tabelle spezifisch benannten Gruppierungen Q-1 .1 bis Q-24.15 steht Q and continue for a specifically designated in the following table groups Q 1 .1 stands to Q 24.15
    Figure imgf000327_0001
    Figure imgf000328_0001
    Figure imgf000328_0002
    Figure imgf000328_0004
    Figure imgf000328_0003
    Figure imgf000329_0001
    Figure imgf000329_0002
    Figure imgf000329_0003
    Figure imgf000330_0001
    Figure imgf000330_0002
    Figure imgf000330_0003
    Q-1.139 Q-1.140 Q-1.141 Q-1.142 Q-1.143 Q-1.144 Q 1139 Q 1140 Q 1141 Q 1142 Q 1143 Q 1144
    Figure imgf000331_0001
    Q-1.157 Q-1.158 Q-1.159 Q-1.160 Q-1.161 Q-1.162 Q 1157 Q 1158 Q 1159 Q 1160 Q 1161 Q 1162
    Figure imgf000331_0002
    Figure imgf000332_0001
    Figure imgf000332_0003
    Figure imgf000332_0002
    Figure imgf000333_0002
    Figure imgf000333_0003
    Figure imgf000333_0001
    Figure imgf000334_0001
    Figure imgf000334_0003
    Figure imgf000334_0004
    V ^ N V ^ N
    H H
    HH HH
    Q-20.7 Q-20.8 Q-20.9 Q-20.10 Q-20.11 Q-20.12 Q 20.7 Q 20.8 Q 20.9 Q 20:10 20:11 Q Q 20:12
    - ' \ /\ / OH - ' \ /\ / OH - '\ / \ / OH OH
    HIHIH ii H II \ ' N Π ' N kf 0 0 0 0 0 Hihih II H II \ 'N Π' N kf 0 0 0 0 0
    Q-21.1 Q-21.2 Q-21.3 Q-21.4 Q-21.5 Q-21.6 Q 21.1 Q 21.2 Q 21.3 Q 21.4 Q 21.5 Q 21.6
    Figure imgf000334_0002
    Figure imgf000335_0001
    oooooo oooooo
    OH OH
    Q-22.1 Q-22.2 Q-22.3 Q-22.4 Q-22.5 Q-22.6 Q 22.1 Q 22.2 Q 22.3 Q 22.4 Q 22.5 Q 22.6
    Figure imgf000335_0002
    Behandlung von Pflanzen, umfassend die Applikation einer zur Steigerung der Widerstandsfähigkeit von Pflanzen gegenüber abiotischen Stressfaktoren wirksamen, nicht-toxischen Menge einer oder mehrere der Verbindungen der allgemeinen Formel (I), oder deren Salze gemäß einem der Ansprüche 1 bis 3. Treatment of plants which comprises the application of a for increasing the resistance of plants to abiotic stress factors effective, non-toxic amount of one or more of the compounds of general formula (I) or salts thereof according to any one of claims 1 to 3rd
    Behandlung gemäß Anspruch 4, wobei die abiotischen Streßbedingungen einer oder mehrer Bedingungen ausgewählt aus der Gruppe von Dürre, Kälte- und Trockenstress, osmotischem Streß, Staunässe, erhöhtem Treatment according to claim 4, wherein the abiotic stress conditions of one or more conditions selected from the group of drought, cold and drought stress, osmotic stress, waterlogging, increased
    Bodensalzgehalt, erhöhtem Ausgesetztsein an Mineralien, Ozonbedingungen, Starklichtbedingungen, beschränkter Verfügbarkeit von Stickstoffnährstoffen, beschränkter Verfügbarkeit von Phosphornährstoffen entsprechen. Soil salinity, increased exposure to minerals, exposure to ozone, exposure to strong light, limited availability of nitrogen nutrients, limited availability of phosphorus nutrients correspond.
    Verwendung einer oder mehrerer der offenkettigen Aryl-, Heteroaryl- und Benzylsulfonamidocarbonsäuren, -carbonsäureester, -carbonsäureamide und -carbonitrile oder deren Salze gemäß einem der Ansprüche 1 bis 3 in der Sprühapplikation auf Pflanzen und Pflanzenteilen in Kombinationen mit einem oder mehrer Wirkstoffen ausgewählt aud der Gruppe der Insektizide, Use of one or more of the open-chain aryl, heteroaryl and Benzylsulfonamidocarbonsäuren, carboxylic acid esters, carboxamides or salts thereof and -carbonitrile aud selected according to one of claims 1 to 3 in the spray application to plants or plant parts in combination with one or more active substances of the group of insecticides,
    Lockstoffe, Akarizide, Fungizide, Nematizide, Herbizide, Attractants, miticides, fungicides, nematicides, herbicides,
    wachstumsregulatorische Stoffe, Safener, die Pflanzenreife beeinflussende Stoffe und Bakterizide. growth-regulating substances, safeners, plant maturity influencing substances and bactericides.
    Verwendung einer oder mehrerer der offenkettigen Aryl-, Heteroaryl- und Benzylsulfonamidocarbonsäuren, -carbonsäureester, -carbonsäureamide und -carbonitrile oder deren Salze gemäß einem der Ansprüche 1 bis 3 in der Sprühapplikation auf Pflanzen und Pflanzenteilen in Kombinationen mit Düngemitteln Verwendung einer oder mehrerer der offenkettigen Aryl-, Heteroaryl- und Benzylsulfonamidocarbonsäuren, -carbonsäureester, -carbonsäureamide und -carbonitrile oder deren Salze gemäß einem der Ansprüche 1 bis 3 zur Applikation auf gentechnisch veränderte Sorten, deren Saatgut, oder auf Anbauflächen auf denen diese Sorten wachsen Use of one or more of the open-chain aryl, heteroaryl and Benzylsulfonamidocarbonsäuren, carboxylic acid esters, carboxamides and -carbonitrile or salts thereof according to any one of claims 1 to 3 in the spray application to plants or plant parts in combination with fertilizers using one or more of open-chain aryl -, heteroaryl and Benzylsulfonamidocarbonsäuren, carboxylic acid esters, carboxamides and -carbonitrile or salts thereof according to one of claims 1 to 3 for application to genetically modified varieties whose seed, or on arable land on which to grow these varieties
    Verwendung von Sprühlösungen, die eine oder mehrere der offenkettigen Aryl-, Heteroaryl- und Benzylsulfonamidocarbonsäuren, -carbonsäureester, -carbonsäureamide und -carbonitrile oder deren Salze gemäß einem der Ansprüche 1 bis 3 enthalten, zur Steigerung der Widerstandsfähigkeit von Pflanzen gegenüber abiotischen Stressfaktoren. Use of spray solutions containing one or more of the open-chain aryl, heteroaryl and Benzylsulfonamidocarbonsäuren, carboxylic acid esters, carboxamides and -carbonitrile or salts thereof according to contain one of claims 1 to 3, to increase the resistance of plants to abiotic stress factors.
    Verfahren zur Erhöhung der Stresstoleranz bei Pflanzen ausgewählt aus der Gruppe der Nutzpflanzen, Zierpflanzen, Rasenarten, oder Bäumen, welches die Applikation einer ausreichenden, nicht-toxischen Menge einer oder mehrerer Verbindungen der offenkettigen Aryl-, Heteroaryl- und A method for increasing stress tolerance in plants selected from the group of crops, ornamentals, turf species, or trees, which and the application of a sufficient, non-toxic amount of one or more compounds of the open-chain aryl, heteroaryl
    Benzylsulfonamidocarbonsäuren, -carbonsäureester, -carbonsäureamide und -carbonitrile oder deren Salze gemäß einem der Ansprüche 1 bis 3 auf die Fläche, wo die entsprechende Wirkung gewünscht wird, umfassend die Anwendung auf die Pflanzen, deren Saatgut oder auf die Fläche auf der die Pflanzen wachsen. Benzylsulfonamidocarbonsäuren, carboxylic acid esters, carboxamides and -carbonitrile or salts thereof according to any one of claims 1 to 3 to the area where the corresponding effect is desired which comprises applying to the plants, their seed, or on which the plants grow on the surface.
    Verfahren gemäß Anspruch 10, wobei die Widerstandsfähigkeit der so behandelten Pflanzen gegenüber abiotischem Stress gegenüber nicht behandelten Pflanzen unter ansonsten gleichen physiologischen The method of claim 10, wherein the resistance of the treated plants to abiotic stress as compared with untreated plants under otherwise identical physiological
    Bedingungen um mindestens 3% erhöht ist. Conditions is increased by at least 3%.
Description  translated from German

Verwendung von offenkettigen Aryl-, Heteroaryl- und Use of open-chain aryl, heteroaryl and

Benzylsulfonamidocarbonsäuren, -carbonsäureestern, -carbonsäureamiden und - carbonitrilen oder deren Salze zur Steigerung der Stresstoleranz in Pflanzen. Benzylsulfonamidocarbonsäuren carboxylic acid esters, and -carboxamides - carbonitriles or salts thereof for increasing stress tolerance in plants.

Beschreibung Die Erfindung betrifft die Verwendung von offenkettigen Aryl-, Heteroaryl- und Benzylsulfonamidocarbonsäuren, -carbonsäureestern, -carbonsäureamiden und -carbonitrilen oder deren Salze zur Steigerung der Stresstoleranz in Pflanzen gegenüber abiotischem Stress, sowie zur Steigerung des Pflanzenwachstums und/oder zur Erhöhung des Pflanzenertrags. The invention relates to the use of open-chain aryl, heteroaryl and Benzylsulfonamidocarbonsäuren, carboxylic acid esters, and -carboxamides -carbonitrilen or salts thereof for increasing the stress tolerance in plants to abiotic stress, as well as to increase plant growth and / or for increasing plant yield.

Es ist bekannt, dass bestimmte Arylsulfonamide wie beispielsweise 2- Cyanobenzolsulfonamide Insektizide Eigenschaften besitzen (vgl. z. B. EP0033984 und WO2005035486, WO2006056433, WO2007060220). It is known that certain aryl sulfonamides such as 2- Cyanobenzolsulfonamide insecticidal properties (see. Eg. As EP0033984 and WO2005035486, WO2006056433, WO2007060220). 2- Cyanobenzolsulfonamide mit besonderen heterocyclischen Substitutenten werden in EP2065370 beschrieben. 2- Cyanobenzolsulfonamide with special heterocyclic substituents are described in EP2065370. Es ist weiter bekannt, dass bestimmte substituierte 2- Cyanobenzolsulfonamide als Insektizide im Rahmen von Boden- und It is further known that certain substituted 2- Cyanobenzolsulfonamide and as insecticides in the context of soil

Saatgutanwendungen eingesetzt werden können (vgl. WO2006100271 und Seed treatments can be used (see. WO2006100271 and

WO2006100288). WO2006100288). Die anthelmintische Wirkung von 3-Cyanobenzolsulfonamiden wird in US3821276 beschrieben. The anthelmintic effect of 3-Cyanobenzolsulfonamiden is described in US3821276.

Die Herstellung von Sulfamidoalkancarbonsäuren und The preparation of Sulfamidoalkancarbonsäuren and

Sulfamidoalkancarbonsäurenitrilen wird in DE847006 beschrieben. Sulfamidoalkancarbonsäurenitrilen is described in DE847006. Die Verwendung ausgewählter Arylsulfonamide mit Alkylcarboxyl-Substituenten als Wuchsregulatoren vor allem zur Beschränkung der Wuchslänge von Reis- und Weizenpflanzen mit dem Ziel der Resistenz gegen Umlegen der Halme wird in DE2544859 beschrieben, während die fungizide Wirkung bestimmter N-Cyanoalkylsulfonamiden in EP176327 beschrieben wird. The use of selected arylsulfonamides with alkylcarboxyl substituents as growth regulators primarily for restricting the growth in length of rice and wheat plants with the aim of resistance to folding the blades is described in DE2544859, whereas the fungicidal activity of certain N-Cyanoalkylsulfonamiden is described in EP176327. Es ist außerdem bekannt, daß substituierte N-Sulfonylamino- acetonitrile zur Kontrolle von Parasiten in Warmblütern eingesetzt werden können (vg. WO2004000798). It is also known that substituted N-sulfonylamino acetonitrile to control parasites in warm-blooded animals can be used (vg. WO2004000798). Es ist außerdem bekannt, dass substituierte Arylsulfonamide (vgl. z. B. It is also known that substituted aryl sulfonamides (see. Eg. B.

WO2009105774, WO2006124875, W096/36595) und substitituierte WO2009105774, WO2006124875, W096 / 36595) and substitituierte

Hetarylsulfonamide (vgl. WO20091 13600, WO2007122219) als pharmazeutische Wirkstoffe verwendet werden können. Hetarylsulfonamide (see FIG. WO20091 13600, WO2007122219) can be used as pharmaceutical active ingredients. WO2003007931 beschreibt ebenfalls die pharmazeutische Verwendung von substituierten Naphthylsulfonamiden, während in Eur. J. Med. Chem. 2010, 45, 1760 Naphthylsulfonyl-substituierte WO2003007931 also describes the pharmaceutical use of substituted Naphthylsulfonamiden while in Eur. J. Med. Chem. 2010, 45, 1760 naphthylsulfonyl-substituted

Glutaminsäureamide und ihre Antitumorwirkung beschrieben werden. Glutaminsäureamide and their antitumor activity are described. Weiterhin ist bekannt, daß Pyrrolidinyl-substituierte Arylsulfonamide als Cathepsin C-Inhibitoren bei der Behandlung von Atemwegserkrankungen (WO2009026197) oder als Furthermore, it is known that as a pyrrolidinyl-substituted arylsulfonamides Cathepsin C-inhibitors in the treatment of respiratory diseases (WO2009026197) or as

Antiinfektiva bei der Behandlung von Hepatitis C (WO2007092588) eingesetzt werden können. Anti-infectives can be used in the treatment of hepatitis C (WO2007092588). Die pharmazeutische Verwendung von N-Arylsulfonylderivaten verschiedener weiterer Aminosäuren, zB als Urokinaseinhibitoren (vgl. The pharmaceutical use of N-Arylsulfonylderivaten various other amino acids, such as urokinase inhibitors (see FIG.

WO200005214), als Wirkstoffe zur Behandlung von Diabetes (vgl. WO200309121 1 ), als Analgetika (vgl. WO2008131947) und als γ-Sekretasemodulatoren (vgl. WO200005214), as agents for the treatment of diabetes (see FIG. 1 WO200309121), as analgesics (see FIG. WO2008131947) and as γ-Sekretasemodulatoren (see FIG.

WO2010108067) ist ebenfalls beschrieben. WO2010108067) is also described.

Es ist bekannt, dass Pflanzen auf natürliche Stressbedingungen, wie beispielsweise Kälte-, Hitze-, Trockenstress (Stress verursacht durch Trockenheit und/oder It is known that plants react to natural stress conditions, such as cold, heat, drought stress (stress caused by drought and / or

Wassermangel), Verwundung, Pathogenbefall (Viren, Bakterien, Pilze, Insekten) etc. aber auch auf Herbizide mit spezifischen oder unspezifischen Abwehrmechanismen reagieren können [Pflanzenbiochemie, S. 393-462 , Spektrum Akademischer Verlag, Heidelberg, Berlin, Oxford, Hans W. Heidt, 1996.; Water shortage), wounding, pathogen attack (viruses, bacteria, fungi, insects), etc. but can also to herbicides with specific or unspecific defense mechanisms [Plant Biochemistry, pp 393-462, Cambridge University Press, Heidelberg, Berlin, Oxford, Hans W. Heidt, 1996 .; Biochemistry and Molecular Biology of Plants, S. 1 102-1203, American Society of Plant Physiologists, Rockville, Maryland, eds. Biochemistry and Molecular Biology of Plants, p 1 102-1203, American Society of Plant Physiologists, Rockville, Maryland, eds. Buchanan, Gruissem, Jones, 2000]. Buchanan, Gruissem, Jones, 2000].

In Pflanzen sind zahlreiche Proteine und die sie codierenden Gene bekannt, die an Abwehrreaktionen gegen abiotischen Stress (zB Kälte, Hitze, Trockenheit, Salz, Überflutung) beteiligt sind. In plants many proteins and the genes encoding them are known, which are involved in defense reactions against abiotic stress (eg cold, heat, drought, salinity, flooding). Diese gehören teilweise zu Signaltransduktionsketten (zB Transkriptionsfaktoren, Kinasen, Phosphatasen) oder bewirken eine These include partly to signal transduction chains (for example transcription factors, kinases, phosphatases) or cause

physiologische Antwort der Pflanzenzelle (zB lonentransport, Entgiftung reaktiver Sauerstoff-Spezies). physiological response of the plant cell (eg, ion transport, detoxification of reactive oxygen species). Zu den Signalkettengenen der abiotischen Stressreaktion gehören ua Transkriptionsfaktoren der Klassen DREB und CBF (Jaglo-Ottosen et al., 1998, Science 280: 104-106). The signal chain genes of the abiotic stress response, among other things transcription factors include the classes DREB and CBF (Jaglo-Ottosen et al, 1998 Science 280:. 104-106). An der Reaktion auf Salzstress sind Phosphatasen vom Typ ATPK und MP2C beteiligt. On the response to salt stress phosphatases are involved and the type ATPK MP2C. Ferner wird bei Salzstress häufig die Furthermore, in salt stress often is the

Biosynthese von Osmolyten wie Prolin oder Sucrose aktiviert. Biosynthesis of osmolytes like proline or sucrose activated. Beteiligt sind hier zB die Sucrose-Synthase und Prolin-Transporter (Hasegawa et al., 2000, Annu Rev Plant Physiol Plant Mol Biol 51: 463-499). Involved are here eg the sucrose synthase and proline transporters (Hasegawa et al, 2000, Annu Rev Plant Physiol Plant Mol Biol. 51: 463-499). Die Stressabwehr der Pflanzen gegen Kälte und Trockenheit benutzt zT die gleichen molekularen Mechanismen. The stress resistance of plants to drought and cold sometimes used the same molecular mechanisms. Bekannt ist die Akkumulation von sogenannten Late Embryogenesis Abundant Proteins (LEA- Proteine), zu denen als wichtige Klasse die Dehydrine gehören (Ingram and Bartels, 1996, Annu Rev Plant Physiol Plant Mol Biol 47: 277-403, Close, 1997, Physiol Plant 100: 291 -296). Well known is the accumulation of so-called Late Embryogenesis Abundant proteins (LEA proteins), to which an important class includes the dehydrins (Ingram and Bartels, 1996, Annu Rev Plant Physiol Plant Mol Biol 47: 277-403, Close, 1997, Physiol Plant 100: 291 -296). Es handelt sich dabei um Chaperone, die Vesikel, Proteine und Membranstrukturen in gestressten Pflanzen stabilisieren (Bray, 1993, Plant Physiol 103: 1035-1040). It involves Chaperone, the vesicles, proteins and membrane structures in stressed plants stabilize (Bray, 1993, Plant Physiol 103: 1035-1040). Außerdem erfolgt häufig eine Induktion von Aldehyd- Deydrogenasen, welche die bei oxidativem Stress entstehenden reaktiven In addition, often there is a induction of aldehyde Deydrogenasen which the substances resulting from oxidative stress reactive

Sauerstoff-Spezies (ROS) entgiften (Kirch et al., 2005, Plant Mol Biol 57: 315-332). Oxygen species (ROS) detoxify (Kirch et al, 2005 Plant Mol Biol. 57: 315-332). Heat Shock Faktoren (HSF) und Heat Shock Proteine (HSP) werden bei Hitzestress aktiviert und spielen hier als Chaperone eine ähnliche Rolle wie die Dehydrine bei Kälte- und Trockenstress (Yu et al., 2005, Mol Cells 19: 328-333). Heat Shock factors (HSF) and Heat Shock Proteins (HSP) are activated under heat stress and play here as chaperones a role similar to the dehydrins in cold and drought stress (Yu et al, 2005, Mol Cells. 19: 328-333). Eine Reihe von pflanzenendogenen Signalstoffen, die in die Stresstoleranz bzw. die Pathogenabwehr involviert sind, sind bereits bekannt. A number of plant-endogenous signal substances that are involved in stress tolerance or pathogen defense are already known. Zu nennen sind hier beispielsweise Salicylsäure, Benzoesäure, Jasmonsäure oder Ethylen [Biochemistry and Molecular Biology of Plants, S. 850-929, American Society of Plant These include, for example, salicylic acid, benzoic acid, jasmonic acid or ethylene [Biochemistry and Molecular Biology of Plants, p 850-929, American Society of Plant

Physiologists, Rockville, Maryland, eds. Physiologists, Rockville, Maryland, eds. Buchanan, Gruissem, Jones, 2000]. Buchanan, Gruissem, Jones, 2000]. Einige dieser Substanzen oder deren stabile synthetische Derivate und abgeleitete Some of these substances or their stable synthetic derivatives and derived

Strukturen sind auch bei externer Applikation auf Pflanzen oder Saatgutbeizung wirksam und aktivieren Abwehrreaktionen, die eine erhöhte Stress- bzw. Structures are also effective for external application to plants or seed dressing and activate defense responses, the increased stress or

Pathogentoleranz der Pflanze zur Folge haben [Sembdner, and Parthier, 1993, Ann. Pathogen tolerance of the plant to result in [Sembdner, and Parthier, 1993, Ann. Rev. Plant Physiol. Rev. Plant Physiol. Plant Mol. Biol. 44: 569-589]. Plant Mol Biol. 44:. 569-589].

Es ist weiter bekannt, dass chemische Substanzen die Toleranz von Pflanzen gegen abiotischen Stress erhöhen können. It is further known that chemical substances can increase the tolerance of plants to abiotic stress. Derartige Substanzen werden dabei entweder durch Saatgut-Beizung, durch Blattspritzung oder durch Bodenbehandung appliziert. Such substances are thereby applied either by seed dressing, by foliar application or by Bodenbehandung. So wird eine Erhöhung der abiotischen Stresstoleranz von Kulturpflanzen durch Behandlung mit Elicitoren der System ic Acquired Resistance (SAR) oder So increasing the abiotic stress tolerance of crop plants by treatment with elicitors of System IC Acquired Resistance (SAR) or

Abscisinsäure-Derivaten beschrieben (Schading and Wei, WO200028055; Abrams and Gusta, US5201931 ; Abrams et al, W097/23441 , Churchill et al., 1998, Plant Growth Regul 25: 35-45). Abscisic acid derivatives described (Schading and Wei, WO200028055; Abrams and Gusta, US5201931; Abrams et al, W097 / 23441, Churchill et al, 1998 Plant Growth Regul 25: 35-45.). Desweiteren wurden Effekte von Wachstumsregulatoren auf die Stresstoleranz von Kulturpflanzen beschrieben (Morrison and Andrews, 1992, J Plant Growth Regul 11: 1 13-1 17, RD-259027). Furthermore, effects of growth regulators have been described on the stress tolerance of crops (Morrison and Andrews, 1992, J Plant Growth Regul 11: 1 13-1 17, RD-259 027). In diesem Zusammenhang ist ebenfalls bekannt, dass ein wachstumsregulierendes Naphthylsulfonamid (4-Brom- N-(pyridin-2-ylmethyl)naphthalin-1 -Sulfonamid) die Keimung von Pflanzensamen in der gleichen Weise wie Abscisinsäure beeinflusst (Park et al. Science 2009, 324, 1068-1071 ). In this connection it is also known that a growth-regulating naphthylsulfonamide (4-bromo-N- (pyridin-2-ylmethyl) naphthalene-1 -sulfonamide) affects the germination of plant seeds in the same manner as abscisic acid (Park et al. Science 2009, 324, 1068-1071). Weiterhin zeigt eine Naphthylsulfamidocarbonsäure (N-[(4-Brom-1 - naphthyl)sulfonyl]-5-methoxynorvalin) eine Wirkungsweise in biochemischen Further shows a Naphthylsulfamidocarbonsäure (N - [(4-bromo-1 - naphthyl) sulfonyl] -5-methoxynorvalin) a mode of operation in biochemical

Rezeptortests, die mit 4-Brom-N-(pyridin-2-ylmethyl)naphthalin-1 -Sulfonamid vergleichbar ist (Melcher et al. Nature Structural & Molecular Biology 2010, 17, 1 102-1 108). Receptor assays, which is naphthalen-1 -sulfonamide comparable with 4-bromo-N- (pyridin-2-ylmethyl) (Melcher et al. Nature Structural & Molecular Biology 2010, 17, 1102-1108). Außerdem ist bekannt, dass ein weiteres Naphthylsulfonamid, N-(6- aminohexyl)-5-chlornaphthalin-1 -Sulfonamid, den Calcium-Spiegel in Pflanzen beeinflusst, die einem Kälteschock ausgesetzt wurden (Cholewa et al. Can. J. It is also known that another naphthylsulfonamide, N- (6-aminohexyl) -5-chloronaphthalene-1 influenced -sulfonamide, the calcium level in plants, which were subjected to a cold shock (Cholewa et al. Can. J.

Botany 1997, 75, 375-382). Botany 1997 75, 375-382).

Auch bei Anwendung von Fungiziden, insbesondere aus der Gruppe der Strobilurine oder der Succinat Dehydrogenase Inhibitoren werden ähnliche Effekte beobachtet, die häufig auch mit einer Ertragssteigerung einhergehen (Draber et al., DE3534948, Bartlett et al., 2002, Pest Manag Sei 60: 309). Even with application of fungicides, particularly from the group of the strobilurins or the succinate dehydrogenase inhibitors, similar effects are observed, often associated with an increase in earnings (Draber et al, DE3534948, Bartlett et al, 2002, Pest Manag Be 60:.. 309 ). Es ist ebenfalls bekannt, dass das Herbizid Glyphosat in niedriger Dosierung das Wachstum einiger Pflanzenarten stimuliert (Cedergreen, Env. Pollution 2008, 156, 1099). It is also known that the herbicide glyphosate in low dosage stimulates the growth of some plant species (Cedergreen, Env. Pollution 2008 156 1099).

Bei osmotischem Stress ist eine Schutzwirkung durch Applikation von Osmolyten wie zB Glycinbetain oder deren biochemischen Vorstufen, zB Cholin-Derivate beobachtet worden (Chen et al., 2000, Plant Cell Environ 23: 609-618, Bergmann et al., DE4103253). In osmotic stress is a protective effect by application of osmolytes such as glycine betaine or their biochemical precursors, eg choline derivatives have been observed (Chen et al, 2000, Plant Cell Environ. 23: 609-618, Bergmann et al, DE4103253.). Auch die Wirkung von Antioxidantien wie zB Naphtole und The effect of antioxidants such as naphthols and

Xanthine zur Erhöhung der abiotischen Stresstoleranz in Pflanzen wurde bereits beschrieben (Bergmann et al., DD277832, Bergmann et al., DD277835). Xanthines for increasing abiotic stress tolerance in plants has been described (Bergmann et al., DD277832, Bergmann et al., DD277835). Die molekularen Ursachen der Anti-Stress-Wirkung dieser Substanzen sind jedoch weitgehend unbekannt. However, the molecular mechanisms underlying the anti-stress effect of these substances are largely unknown. Es ist weiter bekannt, dass die Toleranz von Pflanzen gegenüber abiotischem Stress durch eine Modifikation der Aktivität von endogenen Poly-ADP-ribose Polymerasen (PARP) oder Poly-(ADP-ribose) glycohydrolasen (PARG) erhöht werden kann (de Block et al., The Plant Journal, 2004, 41, 95; Levine et al., FEBS Lett. 1998, 440, 1 ; WO0004173; WO04090140). It is further known that the tolerance of plants to abiotic stress by modifying the activity of endogenous poly-ADP-ribose polymerase (PARP) or poly (ADP-ribose) glycohydrolases (PARG) can be increased (de Block et al. , The Plant Journal, 2004, 41, 95; Levine et al, FEBS Lett 1998, 440, 1;.. WO0004173; WO04090140).

Somit ist bekannt, dass Pflanzen über mehrere endogene Reaktionsmechanismen verfügen, die eine wirksame Abwehr gegenüber verschiedensten Schadorganismen und/oder natürlichem abiotischem Stress bewirken können. Thus, it is known that plants have several endogenous reaction mechanisms which can bring about an effective defense against a wide variety of pests and / or natural abiotic stress. Da sich die ökologischen und ökonomischen Anforderungen an moderne Pflanzenbehandlungsmittel laufend erhöhen, beispielsweise was Toxizität, Selektivität, Aufwandmenge, Since the ecological and economical demands made on modern crop treatment agents are increasing constantly, for example with respect to toxicity, selectivity, application rate,

Rückstandsbildung und günstige Herstellbarkeit angeht, besteht die ständige Formation of residues and favorable manufacture, there is a constant

Aufgabe, neue Pflanzenbehandlungsmittel zu entwickeln, die zumindest in Task of developing new plant treatment products, at least in

Teilbereichen Vorteile gegenüber den bekannten aufweisen. Some areas have advantages over the known. Daher bestand die Aufgabe der vorliegenden Erfindung darin, weitere Verbindungen bereitzustellen, die die Toleranz gegenüber abiotischem Stress in Pflanzen erhöhen, eine Stärkung des Pflanzenwachstums bewirken und/oder zur Erhöhung des Therefore, the object of the present invention was to provide further compounds which increase the tolerance to abiotic stress in plants, causing a strengthening of the plant growth and / or increasing the

Pflanzenertrags beitragen. Plant yield contribute. In diesem Zusammenhang wird unter Toleranz In this context under tolerance

gegenüber abiotischem Stress beispielsweise die Toleranz gegenüber Kälte-, Hitze-, Trockenstress (Stress verursacht durch Trockenheit und/oder Wassermangel), abiotic stress, for example, tolerance to cold, heat, drought stress (stress caused by drought and / or lack of water)

Salzen und Überflutung, explizit aber nicht die erhöhte Widerstandskraft gegen das Umlegen der Pflanzen oder von Bestandteilen derselbigen wie beispielsweise bei oder nach schweren Regenfällen und Gewitterstürmen verstanden. Salts and flooding, but explicitly understood derselbigen such as during or after heavy rains and thunderstorms not increased resistance against the folding of plant or components. Gegenstand der vorliegenden Erfindung ist demnach die Verwendung von The present invention accordingly provides the use of

offenkettigen Aryl-, Heteroaryl- und Benzylsulfonamidocarbonsäuren, - carbonsäureestern, -carbonsäureamiden und -carbonitrilen der allgemeinen Formel (I) oder deren Salze open-chain aryl, heteroaryl and Benzylsulfonamidocarbonsäuren, - carboxylic esters and -carboxamides -carbonitrilen of the general formula (I) or salts thereof

Figure imgf000008_0001
zur Toleranzerhöhung gegenüber abiotischem Stress in Pflanzen, worin to increase tolerance to abiotic stress in plants, wherein

Q für die Gruppierungen Q represents the groups

Figure imgf000008_0002

Q-1 Q-20 Q-21 Q-1 Q-20 Q-21

Figure imgf000008_0003

Q-22 Q-23 Q-24 steht, und wobei die Reste R 4 bis R 8 , und R 41 bis R 84 sowie Y und m und p jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zum Schwefelatom der S0 2 -Gruppe steht; Q-22 Q-23 Q-24 is, and where the radicals R 4 to R 8 and R 41 to R 84 and Y and m and p are each as defined in accordance with the following definitions and where the arrow represents a bond to the sulfur atom the S0 2 group;

A 1 , A 2 , A 3 gleich oder verschieden sind und unabhängig voneinander für N A 1, A 2, A 3 are identical or different and are each independently N

(Stickstoff) oder die Gruppierung CW stehen, wobei jedoch in keinem Fall mehr als zwei N-Atome benachbart sind, und wobei W in der Gruppierung C- Wjeweils gleiche oder verschiedene Bedeutungen gemäß der (Nitrogen) or the group CW are, but in no case more than two N atoms are adjacent, and wherein W in the group C- Wjeweils identical or different meanings in accordance with the

nachstehenden Definition hat, definition below has,

W jeweils für Wasserstoff, Nitro, Amino, Cyano, Thiocyanato, Isothiocyanato, Halogen, (Ci-C 8 )-Alkyl, (C 3 -C 8 )-Cycloalkyl, (C 2 -C 8 )-Alkenyl, (C 2 -C 8 )-Alkinyl, Aryl, Aryl-(Ci-Ce)-alkyl, Aryl-(Ci-C 6 )-alkoxy, Heteroaryl, (Ci-Ce)-Alkoxy- (Ci-Ce)-alkyl, (Ci-C 8 )-Haloalkyl, (C 3 -C 8 )-Halocycloalkyl, (Ci-Ce)-Alkoxy, W each represent hydrogen, nitro, amino, cyano, thiocyanato, isothiocyanato, halogen, (Ci-C 8) -alkyl, (C 3 -C 8) cycloalkyl, (C 2 -C 8) -alkenyl, (C 2 - C 8) alkynyl, aryl, aryl (Ci-Ce) alkyl, aryl (Ci-C 6) alkoxy, heteroaryl, (Ci-Ce) alkoxy- (Ci-Ce) alkyl, (Ci- C 8) haloalkyl, (C 3 -C 8) halocycloalkyl, (Ci-Ce) alkoxy,

(Ci-C8)-Haloalkoxy, Aryloxy, Heteroaryloxy, (C3-C8)-Cycloalkyloxy, (C3-C-8)- Cycloalkyl-(Ci-C8)-alkoxy, (Ci-CeJ-Alkoxycarbonyl, (Ci-C6)-Alkoxycarbonyl- (Ci-C6)-alkyl, Hydroxycarbonyl, Aminocarbonyl, (Ci-CeJ-Alkylaminocarbonyl, (C3-C8)-Cycloalkylaminocarbonyl, Cyano-(Ci-C8)-alkylaminocarbonyl, (C2-C-8)- Alkenylaminocarbonyl, (C2-C8)-Alkinylaminocarbonyl, (Ci-C8)-Alkylamino, (Ci-Ce)-Alkylthio, (Ci-C 8 )-Haloalkylthio, Bis-(Ci-C 8 )-alkylamino, (C 3 -C 8 )- Cycloalkylamino, (Ci-C8)-Alkylcarbonylamino, (C3-C-8)- Cycloalkylcarbonylamino, Formylamino, (Ci-C8)-Haloalkylcarbonylamino, (Ci-C8)-Alkoxycarbonylamino, (Ci-C8)-Alkylaminocarbonylamino, Bis-[(Ci-Cs)- Alkyl]-aminocarbonyl-amino, (Ci-C8)-Alkylsulfonylamino, (C3-C-8)- Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl- (Ci-C8)-haloalkylamino, Amino-(Ci-C8)-alkylsulfonyl, Amino-(Ci-C8)- haloalkylsulfonyl, (Ci-CeJ-Alkylsulfonyl, (C3-C8)-Cycloalkylsulfonyl, (Ci-C8) haloalkoxy, aryloxy, heteroaryloxy, (C3-C8) cycloalkyloxy, (C3-C8) - cycloalkyl (Ci-C8) -alkoxy, (Ci-CeJ -alkoxycarbonyl, (Ci-C6) -alkoxycarbonyl- (Ci-C6) alkyl, hydroxycarbonyl, aminocarbonyl, (C CeJ-alkylaminocarbonyl, (C3-C8) cycloalkylaminocarbonyl, cyano (C C8) alkylaminocarbonyl, (C2-C8) - alkenylaminocarbonyl, (C2-C8) -Alkinylaminocarbonyl, (Ci-C8) alkylamino, (Ci-Ce) alkylthio, (Ci-C8) haloalkylthio, bis (Ci-C 8) alkylamino, (C 3 -C 8 ) - cycloalkylamino, (Ci-C8) alkylcarbonylamino, (C3-C8) - cycloalkylcarbonylamino, formylamino, (Ci-C8) -Haloalkylcarbonylamino, (Ci-C8) alkoxycarbonylamino, (Ci-C8) alkylaminocarbonylamino, bis [(Ci-Cs) - alkyl] aminocarbonyl-amino, (Ci-C8) alkylsulfonylamino, (C3-C-8) - cycloalkylsulfonylamino, arylsulfonylamino, Hetarylsulfonylamino, sulfonyl (Ci-C8) -haloalkylamino, amino (Ci C8) alkylsulfonyl, amino (Ci-C8) - haloalkylsulfonyl, (Ci-CeJ-alkylsulfonyl, (C3-C8) cycloalkylsulfonyl,

Arylsulfonyl, (Ci-Ce)-Alkylsulfinyl, (C3-C 8 )-Cycloalkylsulfinyl, Arylsulfinyl, N,S- Di-(Ci-C 8 )-alkylsulfonimidoyl, S-(Ci-C 8 )-Alkylsulfonimidoyl, (Ci-C 8 )- Alkylsulfonylaminocarbonyl, (C3-C8)-Cycloalkylsulfonylaminocarbonyl, (C3-C-8)- Cycloalkylaminosulfonyl, Aryl-(Ci-C8)-alkylcarbonylamino, (C3-C8)-Cycloalkyl- (Ci-C8)-alkylcarbonylamino, Heteroarylcarbonylamino, (Ci-C8)-Alkoxy-(Ci-C-8)- alkylcarbonylamino, Hydroxy-(Ci-C8)-alkylcarbonylamino steht, für H, Nitro, Amino, Cyano, Halogen, (Ci-C 8 )-Alkyl, (C 3 -C 8 )-Cycloalkyl, (C 2 -C 8 )-Alkenyl, (C 2 -C 8 )-Alkinyl, Aryl, Aryl-(Ci-C 8 )-alkyl, Heteroaryl, (Ci-C 8 )- Alkoxy-(Ci-C 8 )-alkyl, (Ci-C 8 )-Haloalkyl, (C 3 -C 8 )-Halocycloalkyl, (Ci-C 8 )-Alkoxy, (Ci-C 8 )-Haloalkoxy, (Ci-C 8 )-Alkylthio, (Ci-C 8 )-Haloalkylthio, (Ci-C 8 )- Alkoxycarbonyl, Hydroxycarbonyl, Aminocarbonyl, (Ci-Cs)- Alkylaminocarbonyl, (Ci-C8)-Alkylamino, Bis-(Ci-C8)-alkylamino, (C3-C8)- Cycloalkylamino, (Ci-C8)-Alkylcarbonylamino, (C3-C8)- Cycloalkylcarbonylamino, Formylamino, (Ci-C8)-Haloalkylcarbonylamino, (Ci-C8)-Alkoxycarbonylamino, [(Ci-C8)-Alkyl-]aminocarbonyl-amino, Arylsulfonyl, (Ci-Ce) alkylsulfinyl, (C3-C8) -Cycloalkylsulfinyl, arylsulfinyl, N, S di- (Ci-C 8) -alkylsulfonimidoyl, S- (Ci-C 8) -Alkylsulfonimidoyl, (Ci C 8) - alkylsulphonylaminocarbonyl, (C3-C8) -Cycloalkylsulfonylaminocarbonyl, (C3-C8) - Cycloalkylaminosulfonyl, aryl (Ci-C8) alkylcarbonylamino, (C3-C8) cycloalkyl- (Ci-C8) alkylcarbonylamino, heteroarylcarbonylamino, (Ci-C8) alkoxy- (Ci-C-8) - alkylcarbonylamino, hydroxy (Ci-C8) alkylcarbonylamino, represents H, nitro, amino, cyano, halogen, (Ci-C 8) -alkyl , (C 3 -C 8) cycloalkyl, (C 2 -C 8) -alkenyl, (C 2 -C 8) alkynyl, aryl, aryl (Ci-C 8) alkyl, heteroaryl, (Ci-C 8) - alkoxy (Ci-C 8) alkyl, (Ci-C8) -haloalkyl, (C 3 -C 8) halocycloalkyl, (Ci-C 8) alkoxy, (Ci-C8) -haloalkoxy , (Ci-C8) alkylthio, (Ci-C8) haloalkylthio, (Ci-C 8) - alkoxycarbonyl, hydroxycarbonyl, aminocarbonyl, (Ci-Cs) - alkylaminocarbonyl, (Ci-C8) alkylamino, bis (Ci-C8) alkylamino, (C3-C8) - cycloalkylamino, (Ci-C8) alkylcarbonylamino, (C3-C8) - cycloalkylcarbonylamino, formylamino, (Ci-C8) -Haloalkylcarbonylamino, (Ci-C8) alkoxycarbonylamino, [(Ci-C8) alkyl] aminocarbonyl-amino,

Sulfonylamino, (Ci-C8)-Alkylsulfonylamino, (Ci-C8)-Haloalkylsulfonylamino, (C3-C8)-Cycloalkylsulfonylamino, Amino-(Ci-C8)-alkylsulfonyl, Amino-(Ci-C8)- haloalkylsulfonyl, (Ci-C8)-Alkylsulfonyl, (C3-C8)-Cycloalkylsulfonyl, Sulfonylamino, (Ci-C8) alkylsulfonylamino, (Ci-C8) -Haloalkylsulfonylamino, (C3-C8) -Cycloalkylsulfonylamino, amino (Ci-C8) alkylsulfonyl, amino (Ci-C8) - haloalkylsulfonyl, (Ci-C8 ) alkylsulfonyl, (C3-C8) cycloalkylsulfonyl,

Arylsulfonyl, (Ci-Ce)-Alkylsulfinyl, (C 3 -C 8 )-Cycloalkylsulfinyl, Arylsulfinyl, N,S- Di-(Ci-C 8 )-alkylsulfonimidoyl, S-(Ci-C 8 )-Alkylsulfonimidoyl, (Ci-C 8 )- Alkylsulfonylaminocarbonyl, (C3-C8)-Cycloalkylsulfonylaminocarbonyl, (C3-C8)- Cycloalkylaminosulfonyl, Amino-(Ci-C8)-alkyl, Amino-(C2-C8)-alkenyl, (C2-C8)- Alkenylamino, (C2-C8)-Alkenylimino steht, Arylsulfonyl, (Ci-Ce) alkylsulfinyl, (C 3 -C 8) -Cycloalkylsulfinyl, arylsulfinyl, N, S-di- (Ci-C 8) -alkylsulfonimidoyl, S- (Ci-C 8) -Alkylsulfonimidoyl, (C -C 8) - alkylsulphonylaminocarbonyl, (C3-C8) -Cycloalkylsulfonylaminocarbonyl, (C3-C8) - Cycloalkylaminosulfonyl, amino (Ci-C8) alkyl, amino (C2-C8) alkenyl, (C2-C8) - alkenylamino , (C2-C8) -Alkenylimino stands,

R 2 für H, Nitro, Amino, Cyano, Halogen, (Ci-C 8 )-Alkyl, (C 3 -C 8 )-Cycloalkyl, R 2 is H, nitro, amino, cyano, halogen, (Ci-C 8) alkyl, (C 3 -C 8) -cycloalkyl,

(C 2 -C 8 )-Alkenyl, (C 2 -C 8 )-Alkinyl, Aryl, Aryl-(Ci-C 8 )-alkyl, Heteroaryl, (Ci-C 8 )- Alkoxy-(Ci-C 8 )-alkyl, (Ci-C 8 )-Haloalkyl, (C 3 -C 8 )-Halocycloalkyl, (Ci-C 8 )-Alkoxy, (Ci-C 8 )-Haloalkoxy, (Ci-C 8 )-Alkylthio, (Ci-C 8 )-Haloalkylthio, (Ci-C 8 )- Alkoxycarbonyl, Hydroxycarbonyl, Aminocarbonyl, (Ci-Cs)- Alkylaminocarbonyl, (Ci-C8)-Alkylamino, Bis-(Ci-C8)-alkylamino, (C3-C8)- Cycloalkylamino, (Ci-C8)-Alkylcarbonylamino, (C3-C8)- Cycloalkylcarbonylamino, Formylamino, (Ci-C8)-Haloalkylcarbonylamino, (Ci-C8)-Alkoxycarbonylamino, [(Ci-C8)-Alkyl-]-aminocarbonyl-amino, (C 2 -C 8) -alkenyl, (C 2 -C 8) alkynyl, aryl, aryl (Ci-C 8) alkyl, heteroaryl, (Ci-C 8) - alkoxy (Ci-C 8) alkyl, (Ci-C8) -haloalkyl, (C 3 -C 8) halocycloalkyl, (Ci-C 8) alkoxy, (Ci-C8) haloalkoxy, (Ci-C8) alkylthio, ( Ci-C 8) haloalkylthio, (Ci-C 8) - alkoxycarbonyl, hydroxycarbonyl, aminocarbonyl, (Ci-Cs) - alkylaminocarbonyl, (Ci-C8) alkylamino, bis (Ci-C8) alkylamino, (C 3 C8) - cycloalkylamino, (Ci-C8) alkylcarbonylamino, (C3-C8) - cycloalkylcarbonylamino, formylamino, (Ci-C8) -Haloalkylcarbonylamino, (Ci-C8) alkoxycarbonylamino, [(Ci-C8) alkyl -] - aminocarbonyl-amino,

Sulfonylamino, (Ci-C8)-Alkylsulfonylamino, (Ci-C8)-Haloalkylsulfonylamino, (C3-C8)-Cycloalkylsulfonylamino, Amino-(Ci-C8)-alkylsulfonyl, Amino-(Ci-C8)- haloalkylsulfonyl, (Ci-C8)-Alkylsulfonyl, (C3-C8)-Cycloalkylsulfonyl, Sulfonylamino, (Ci-C8) alkylsulfonylamino, (Ci-C8) -Haloalkylsulfonylamino, (C3-C8) -Cycloalkylsulfonylamino, amino (Ci-C8) alkylsulfonyl, amino (Ci-C8) - haloalkylsulfonyl, (Ci-C8 ) alkylsulfonyl, (C3-C8) cycloalkylsulfonyl,

Arylsulfonyl, (Ci-C 8 )-Alkylsulfinyl, (C 3 -C 8 )-Cycloalkylsulfinyl, Arylsulfinyl, N,S- Di-(Ci-C 8 )-alkylsulfonimidoyl, S-(Ci-C 8 )-Alkylsulfonimidoyl, (Ci-C 8 )- Alkylsulfonylaminocarbonyl, (C3-C8)-Cycloalkylsulfonylaminocarbonyl, (C3-C8)- Cycloalkylaminosulfonyl, Amino-(Ci-C8)-alkyl, Amino-(C2-C8)-alkenyl, (C2-C8)- Alkenylamino, (C2-C8)-Alkenylimino steht, Arylsulfonyl, (Ci-C8) alkylsulfinyl, (C 3 -C 8) -Cycloalkylsulfinyl, arylsulfinyl, N, S-di- (Ci-C 8) -alkylsulfonimidoyl, S- (Ci-C 8) -Alkylsulfonimidoyl, ( Ci-C 8) - alkylsulphonylaminocarbonyl, (C3-C8) -Cycloalkylsulfonylaminocarbonyl, (C3-C8) - Cycloalkylaminosulfonyl, amino (Ci-C8) alkyl, amino (C2-C8) alkenyl, (C2-C8) - alkenylamino, (C2-C8) -Alkenylimino stands,

R 1 und R 2 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten, teilgesättigten oder vollständig ungesättigten, gegebenenfalls durch R 1 and R 2 with the atoms to which they are attached form a fully saturated, partially saturated or fully unsaturated, optionally substituted by

Heteroatome unterbrochenen und gegebenenfalls weiter durch W Heteroatoms and optionally further interrupted by W

substituierten 5 bis 7-gliedrigen Ring bilden, und wobei sie im Falle der Verbindungen der allgemeinen Formel (I) mit den Gruppierungen Q-21 und Q- 23 einen entsprechenden Ring bilden müssen. substituted 5 to 7-membered ring, and being (I) to form with the moieties Q-21 and Q 23, a corresponding ring in the case of compounds of the general formula. R 1 und A 3 , wenn A 3 für eine Gruppe CW steht, mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten, teilgesättigten oder vollständig R 1 and A 3, when A 3 is a group CW, with the atoms to which they are attached form a fully saturated, partially saturated or fully

ungesättigten, gegebenenfalls durch Heteroatome unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, unsaturated, optionally interrupted by hetero atoms and optionally further substituted form 5 to 7-membered ring,

X für eine direkte Bindung oder für eine Gruppierung (CHR 3 ) n steht, und wobei R 3 in der Gruppierung (CHR 3 ) n jeweils gleiche oder verschiedene X represents a direct bond or a group (CHR 3) n and wherein R 3 in the group (CHR 3) n are identical or different

Bedeutungen gemäß der nachstehenden Definition hat, n für 0, 1 steht Meanings as defined below, has n is 0, 1 is

R 3 für H, (Ci -Ce)-Alkyl, (C 2 -Ce)-Alkenyl-(Ci -Ce)-alkyl, (Ci-C 8 )-Haloalkyl, (C 3 -C 8 )- Cycloalkyl, (C3-C 8 )-Cycloalkyl-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkyl, Heteroaryl- (Ci -Cs)-alkyl, (Ci-C 8 )-Alkoxy-(Ci-C 8 )-alkyl, (Ci-C 8 )-Haloalkoxy-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkylthio-(Ci-C 8 )-alkyl, (Ci-C 8 )-Haloalkylthio-(Ci-C 8 )-alkyl steht, R 3 is H, (Ci -Ce) alkyl, (C 2 -Ce) alkenyl (Ci -Ce) alkyl, (Ci-C8) -haloalkyl, (C 3 -C 8) - cycloalkyl, ( C3-C8) cycloalkyl (Ci-C 8) alkyl, aryl (Ci-C 8) alkyl, heteroaryl (Ci -Cs) alkyl, (Ci-C 8) alkoxy (Ci C 8) alkyl, (Ci-C 8) haloalkoxy (Ci-C 8) alkyl, (Ci-C8) alkylthio (Ci-C 8) alkyl, (Ci-C8) haloalkylthio - (Ci-C 8) -alkyl,

R 4 für H, (Ci -Cs)-Alkyl, (C 2 -C 8 )-Alkenyl-(Ci-C 8 )-alkyl, (C 2 -C 8 )-Alkinyl, (Ci-C 8 )- Alkylcarbonyl, (C3-C 8 )-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl, (Ci-C 8 )-Alkoxycarbonyl, Aryl-(Ci-C 8 )-alkoxycarbonyl, (C3-C 8 )- Cycloalkoxycarbonyl, (C3-C 8 )-Cycloalkyl-(Ci-C 8 )-alkoxycarbonyl, (Ci-C 8 )- Alkylsulfonyl, (C 3 -C 8 )-Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C 8 )- Alkoxycarbonylcarbonyl, Aryl-(Ci-C 8 )-alkoxycarbonylcarbonyl, (Ci-C 8 )- Alkylaminothiocarbonyl, (Ci -Cs)-Alkylaminocarbonyl, Aryl-(Ci-C 8 )-alkyl, Hetaroaryl-(Ci-C 8 )-alkyl, Cyano-(Ci-C 8 )-alkyl, (Ci -Cs)-Haloalkyl, (C 3 -C 8 )- Cycloalkyl, (C 3 -C 8 )-Cycloalkyl-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkoxy-(Ci-C 8 )-alkyl, R 4 is H, (Ci -Cs) alkyl, (C 2 -C 8) alkenyl (Ci-C 8) alkyl, (C 2 -C 8) alkynyl, (Ci-C 8) - alkylcarbonyl , (C3-C8) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl, (Ci-C8) -alkoxycarbonyl, aryl (Ci-C8) -alkoxycarbonyl, (C3-C8) - cycloalkoxycarbonyl, (C3-C8) - cycloalkyl (Ci-C8) alkoxycarbonyl, (Ci-C 8) - alkylsulfonyl, (C 3 -C 8) cycloalkylsulfonyl, arylsulfonyl, (Ci-C 8) - alkoxycarbonylcarbonyl, aryl (Ci-C 8) - alkoxycarbonylcarbonyl, (Ci-C 8) - alkylaminothiocarbonyl, (Ci -Cs) alkylaminocarbonyl, aryl (Ci-C 8) alkyl, Hetaroaryl- (Ci-C 8) -alkyl, cyano- (Ci-C 8) - alkyl, (Ci -Cs) -haloalkyl, (C 3 -C 8) - cycloalkyl, (C 3 -C 8) cycloalkyl (Ci-C 8) alkyl, (Ci-C 8) alkoxy (Ci -C 8) alkyl,

(Ci-C 8 )-Haloalkoxy-(Ci-C 8 )-alkyl, (C 2 -C 8 )-Alkinyl-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkoxycarbonyl-(Ci-C 8 )-alkyl, Aminocarbonyl-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkylaminocarbonyl-(Ci-C 8 )-alkyl, Bis-(Ci-C 8 )-alkylaminocarbonyl-(Ci-C 8 )-alkyl steht, für Halogen, (C2-Ce)-Alkyl, (Ci-C 8 )-Alkoxy, (Ci-C 8 )-Alkoxycarbonyloxy, (Ci-C 8) haloalkoxy (Ci-C 8) alkyl, (C 2 -C 8) alkynyl (Ci-C 8) alkyl, (Ci-C8) - alkoxycarbonyl (Ci-C 8) alkyl, aminocarbonyl (Ci-C 8) alkyl, (Ci-C 8) - alkylaminocarbonyl (Ci-C8) alkyl, bis (Ci-C 8) alkylaminocarbonyl (Ci-C 8 ) -alkyl, halogen, (C2-Ce) alkyl, (Ci-C 8) alkoxy, (Ci-C 8) -alkoxycarbonyloxy,

(C 2 -C 8 )-Alkenyl, (C 2 -C 8 )-Haloalkenyl, (C 2 -C 8 )-Alkenyl-(Ci-C 8 )-alkyl, (C 2 -C 8 )- Alkinyl, (C 2 -C 8 )-Alkinyl-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkyl, Bisaryl-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkoxyaryl-(Ci-C 8 )-alkyl, Aryloxyaryl-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkoxyaryl-(Ci-C 8 )-alkyl, Heteroaryl-(Ci-C 8 )-alkyl, Heterocyclyl-(Ci-C 8 )-alkyl, N-(Ci-C 8 )-Alkylheterocyclyl-(Ci-C 8 )-alkyl, N-[(Ci-C 8 )- Alkoxycarbonyl]heterocyclyl-(Ci-C 8 )-alkyl, N-(Aryl-(Ci-C 8 )- alkoxycarbonyl)heterocyclyl-(Ci-C 8 )-alkyl, N-(Arylcarbonyl)heterocyclyl- (Ci-Cs)-alkyl, N-[(Ci-C 8 )-Alkylcarbonyl]heterocyclyl-(Ci-C 8 )-alkyl, N-[(C 3 -C 8 )- Cycloalkylcarbonyl]heterocyclyl-(Ci-C 8 )-alkyl, Cyano-(Ci-C 8 )-alkyl, (Ci-C 8 )- Haloalkyl, (C 3 -C 8 )-Cycloalkyl, (C 3 -C 8 )-Halocycloalkyl, (C 4 -C 8 )-Cycloalkenyl, (C 3 -C 8 )-Cycloalkyl-(Ci-C 8 )-alkyl, (C 3 -C 8 )-Cycloalkenyl-(Ci-C 8 )-alkyl, Hydroxy- (Ci-Cs)-alkyl, (Ci-C 8 )-Alkoxy-(Ci-C 8 )-alkyl, (Ci-C 8 )-Haloalkoxy-(Ci-C 8 )-alkyl, Aryloxy-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkoxy-(Ci-C 8 )-alkyl, Heteroaryl-(Ci-Cs)- alkoxy-(Ci-C 8 )-alkyl, (C 3 -C 8 )-Cycloalkoxy-(Ci-C 8 )-alkyl, (C 3 -C 8 )-Cycloalkyl- (Ci-C 8 )-alkoxy-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkylcarbonyloxy-(Ci-C 8 )-alkyl, (C 2 -C 8) -alkenyl, (C 2 -C 8) haloalkenyl, (C 2 -C 8) alkenyl (Ci-C 8) alkyl, (C 2 -C 8) - alkynyl, ( C 2 -C 8) alkynyl (Ci-C 8) alkyl, aryl (Ci-C 8) alkyl, bisaryl (Ci-C 8) alkyl, aryl (Ci-C 8) alkoxyaryl - (Ci-C 8) alkyl, Aryloxyaryl- (Ci-C 8) alkyl, (Ci-C 8) - alkoxyaryl (Ci-C 8) alkyl, heteroaryl (Ci-C 8) alkyl, heterocyclyl (Ci-C 8) -alkyl, N- (Ci-C 8) -Alkylheterocyclyl- (Ci-C 8) -alkyl, N - [(Ci-C8) - alkoxycarbonyl] heterocyclyl (Ci-C 8 ) alkyl, N- (aryl (Ci-C8) - alkoxycarbonyl) heterocyclyl- (Ci-C 8) alkyl, N- (arylcarbonyl) heterocyclyl (Ci-Cs) -alkyl, N - [(Ci- C 8) alkylcarbonyl] heterocyclyl (Ci-C 8) -alkyl, N - [(C 3 -C 8) - cycloalkylcarbonyl] heterocyclyl (Ci-C8) alkyl, cyano (Ci-C 8) - alkyl, (Ci-C 8) - haloalkyl, (C 3 -C 8) cycloalkyl, (C 3 -C 8) halocycloalkyl, (C 4 -C 8) cycloalkenyl, (C 3 -C 8) cycloalkyl - (Ci-C 8) alkyl, (C 3 -C 8) cycloalkenyl (Ci-C 8) -alkyl, hydroxy- (Ci-Cs) alkyl, (Ci-C 8) alkoxy (Ci -C 8) alkyl, (Ci-C 8) haloalkoxy (Ci-C 8) alkyl, aryloxy (Ci-C8) alkyl, aryl (Ci-C 8) alkoxy (Ci C 8) alkyl, heteroaryl (Ci-Cs) - alkoxy- (Ci-C 8) alkyl, (C 3 -C 8) cycloalkoxy (Ci-C 8) alkyl, (C 3 -C 8 ) cycloalkyl (Ci-C 8) alkoxy (Ci-C 8) alkyl, (Ci-C8) alkylcarbonyloxy (Ci-C8) alkyl,

Arylcarbonyloxy-(Ci-C 8 )-alkyl, Heteroarylcarbonyloxy-(Ci-C 8 )-alkyl, (C 3 -C 8 )- Cycloalkylcarbonyloxy-(Ci-C 8 )-alkyl, Arylsulfonyloxy-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkylsulfonyloxy-(Ci-C 8 )-alkyl, Hydrothio-(Ci-C 8 )-alkyl, (Ci-Cs)-Alkylthio- (Ci-Cs)-alkyl, (Ci-C 8 )-Haloalkylthio-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkylthio- (Ci-Cs)-alkyl, (C 3 -C 8 )-Cycloalkylthio-(Ci-C 8 )-alkyl, Arylthio-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkylsulfinyl-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkylsulfonyl-(Ci-C 8 )-alkyl, (Ci-C 8 )- Haloalkylsulfinyl-(Ci-C 8 )-alkyl, (Ci-C 8 )-Haloalkylsulfonyl-(Ci-C 8 )-alkyl, Aryl- (Ci-C 8 )-alkylsulfinyl-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkylsulfonyl-(Ci-C 8 )-alkyl, (C 3 -C 8 )-Cycloalkylsulfinyl-(Ci-C 8 )-alkyl, (C 3 -C 8 )-Cycloalkylsulfonyl-(Ci-C 8 )- alkyl, Aryl, Heteroaryl, Heterocyclyl, N-[(Ci-C 8 )-Alkyl]heterocyclyl, N-[(Ci-C 8 )- Alkoxycarbonyl]heterocyclyl, N-[Aryl-(Ci-C 8 )-alkoxycarbonyl]heterocyclyl, N- (Arylcarbonyl)heterocyclyl, N-[(Ci-C 8 )-Alkylcarbonyl]heterocyclyl, N-[(Ci-C 8 )- Cycloalkylcarbonyl]heterocyclyl, Hydroxycarbonyl, (Ci-Cs)-Alkoxycarbonyl, (C 3 -C 8 )-Cycloalkoxycarbonyl, (C 3 -C 8 )-Cycloalkyl-(Ci-C 8 )-alkoxycarbonyl, Aryl- (Ci-C 8 )-alkoxycarbonyl, Heteroaryl-(Ci-C 8 )-alkoxycarbonyl, (Ci-C 8 )- Alkylaminocarbonyl, Aminocarbonyl, Bis-(Ci-C 8 )-alkylaminocarbonyl, (C 3 -C 8 )- Cycloalkylaminocarbonyl, Aryl-(Ci-C8)-alkylaminocarbonyl, Arylcarbonyloxy (Ci-C 8) alkyl, Heteroarylcarbonyloxy- (Ci-C 8) alkyl, (C 3 -C 8) - Cycloalkylcarbonyloxy- (Ci-C 8) alkyl, arylsulfonyloxy (Ci-C 8) - alkyl, (Ci-C 8) - alkylsulfonyloxy (Ci-C 8) alkyl, Hydrothio- (Ci-C 8) alkyl, (Ci-Cs) alkylthio (Ci-Cs) alkyl, (Ci- C 8) -Haloalkylthio- (Ci-C 8) alkyl, aryl (Ci-C8) alkylthio (Ci-Cs) alkyl, (C 3 -C 8) cycloalkylthio (Ci-C 8) alkyl, arylthio (Ci-C 8) alkyl, (Ci-C8) alkylsulfinyl (Ci-C 8) alkyl, (Ci-C8) alkylsulfonyl (Ci-C 8) alkyl, (Ci-C 8) - Haloalkylsulfinyl- (Ci-C 8) alkyl, (Ci-C 8) -Haloalkylsulfonyl- (Ci-C 8) alkyl, aryl (Ci-C8) alkylsulfinyl (CI- C 8) alkyl, aryl (Ci-C8) alkylsulfonyl (Ci-C 8) alkyl, (C 3 -C 8) -Cycloalkylsulfinyl- (Ci-C 8) alkyl, (C 3 -C 8) -Cycloalkylsulfonyl- (Ci-C 8) - alkyl, aryl, heteroaryl, heterocyclyl, N - [(Ci-C 8) -alkyl] heterocyclyl, N - [(Ci-C8) - alkoxycarbonyl] heterocyclyl, N- [aryl- (Ci-C8) -alkoxycarbonyl] heterocyclyl, N- (arylcarbonyl) heterocyclyl, N - [(Ci-C 8) alkylcarbonyl] heterocyclyl, N - [(Ci-C 8) - cycloalkylcarbonyl] heterocyclyl, hydroxycarbonyl , (Ci-Cs) -alkoxycarbonyl, (C 3 -C 8) -cycloalkoxycarbonyl, (C 3 -C 8) cycloalkyl (Ci-C8) alkoxycarbonyl, aryl (Ci-C8) -alkoxycarbonyl, heteroaryl - (Ci-C8) alkoxycarbonyl, (Ci-C 8) - alkylaminocarbonyl, aminocarbonyl, bis (Ci-C 8) alkylaminocarbonyl, (C 3 -C 8) - cycloalkylaminocarbonyl, aryl (Ci-C8) - alkylaminocarbonyl,

Heteroarylaminocarbonyl, Cyano-(Ci-C8)-alkylaminocarbonyl, (Ci-Cs)- Haloalkylaminocarbonyl, (C2-C8)-Alkinyl-(Ci-C8)-alkylaminocarbonyl, Heteroarylaminocarbonyl, cyano (Ci-C8) alkylaminocarbonyl, (Ci-Cs) - Haloalkylaminocarbonyl, (C2-C8) alkynyl (Ci-C8) alkylaminocarbonyl,

Hydroxycarbonyl-(Ci-Ce)-alkyl, (Ci-C 8 )-Alkoxycarbonyl-(Ci-C 8 )-alkyl, (C 3 -C 8 )- Cycloalkoxycarbonyl-(Ci-C8)-alkyl, (C3-C8)-Cycloalkyl-(Ci-C8)-alkoxycarbonyl- (Ci-Ce)-alkyl, Aryl-(Ci-C 8 )-alkoxycarbonyl-(Ci-C 8 )-alkyl, Heteroaryl-(Ci-C 8 )- alkoxycarbonyl-(Ci-C8)-alkyl, (Ci-C8)-Alkylaminocarbonyl-(Ci-C8)-alkyl, Aminocarbonyl-(Ci-C8)-alkyl, Bis-(Ci-C8)-alkylaminocarbonyl-(Ci-C8)-alkyl, (C3-C8)-Cycloalkylaminocarbonyl-(Ci-C 8 )-alkyl, Aryl-(Ci-Ce)- alkylaminocarbonyl-(Ci-C8)-alkyl, Heteroarylaminocarbonyl-(Ci-C8)-alkyl, Cyano-(Ci-C8)-alkylaminocarbonyl-(Ci-C8)-alkyl, (Ci-Ce)- Haloalkylaminocarbonyl-(Ci-C 8 )-alkyl, (C2-C 8 )-Alkinyl-(Ci-C 8 )- alkylaminocarbonyl-(Ci-C8)-alkyl, Amino-(Ci-C8)-alkyl, (Ci-C8)-Alkylamino- (Ci-Ce)-alkyl, (C2-C 8 )-Alkenylamino-(Ci-C 8 )-alkyl, Arylamino-(Ci-C 8 )-alkyl, Bis- (Ci-C8)-alkylamino-(Ci-C8)-alkyl, Bis-(C3-C8)-cycloalkylamino-(Ci-C8)-alkyl, Aryl-(Ci-C 8 )-alkylamino-(Ci-C 8 )-alkyl, Tns-Aryl-(Ci-C 8 )-alkylamino-(Ci-C 8 )- alkyl, (C3-C8)-Cycloalkylamino-(Ci-C 8 )-alkyl, (C3-C 8 )-Cycloalkyl-(Ci-C 8 )- alkylamino-(Ci-C 8 )-alkyl, (Ci-C 8 )-Haloalkylamino-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkylcarbonylamino-(Ci-C8)-alkyl, (Ci-C8)-Cycloalkylcarbonylamino-(Ci-C8)- alkyl, Arylcarbonylamino-(Ci-C8)-alkyl, Heteroarylcarbonylamino-(Ci-C8)-alkyl, (Ci-C8)-Alkoxycarbonylamino-(Ci-C8)-alkyl, (C2-C8)-Alkenyloxycarbonylamino- (Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkoxycarbonylamino-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )- alkoxycarbonyl[N-(Ci-C8)-alkyl]amino-(Ci-C8)-alkyl, Heteroaryl-(Ci-C8)- alkoxycarbonylamino-(Ci-C8)-alkyl, (C3-C8)-Cycloalkyl-(Ci-C8)- alkoxycarbonylamino-(Ci-C8)-alkyl, (C3-C8)-Cycloalkoxycarbonylamino- (Ci-C8)-alkyl, Aminocarbonylamino-(Ci-C8)-alkyl, Arylsulfonylamino-(Ci-C8)- alkyl, Heteroarylsulfonylamino-(Ci-C8)-alkyl, (Ci-C8)-Alkylsulfonylamino- (Ci-C 8 )-alkyl, (C3-C8)-Cycloalkylsulfonylamino-(Ci-C 8 )-alkyl, Hydroxycarbonyl (Ci-Ce) alkyl, (Ci-C8) alkoxycarbonyl (Ci-C 8) alkyl, (C 3 -C 8) - Cycloalkoxycarbonyl- (Ci-C8) alkyl, (C3-C8 ) cycloalkyl (Ci-C8) alkoxycarbonyl (Ci-Ce) alkyl, aryl (Ci-C8) alkoxycarbonyl (Ci-C 8) alkyl, heteroaryl (Ci-C8) - alkoxycarbonyl - (Ci-C8) alkyl, (Ci-C8) alkylaminocarbonyl (Ci-C8) alkyl, aminocarbonyl (Ci-C8) alkyl, bis (Ci-C8) alkylaminocarbonyl (Ci-C8) alkyl, (C3-C8) -Cycloalkylaminocarbonyl- (Ci-C8) alkyl, aryl (Ci-Ce) - alkylaminocarbonyl (Ci-C8) alkyl, Heteroarylaminocarbonyl- (Ci-C8) alkyl, cyano (Ci-C8) alkylaminocarbonyl (Ci-C8) alkyl, (Ci-Ce) - Haloalkylaminocarbonyl- (Ci-C 8) alkyl, (C2-C8) alkynyl (Ci-C 8) - alkylaminocarbonyl - (Ci-C8) alkyl, amino (Ci-C8) alkyl, (Ci-C8) alkylamino (Ci-Ce) alkyl, (C2-C8) -Alkenylamino- (Ci-C 8) alkyl, arylamino (Ci-C 8) alkyl, bis (Ci-C8) alkylamino (Ci-C8) alkyl, bis- (C3-C8) cycloalkylamino (Ci-C8) alkyl, aryl (Ci-C 8) alkylamino (C 8) alkyl, aryl TNS (Ci-C 8) alkylamino (C 8) - alkyl, (C3-C8) cycloalkylamino (Ci-C 8) alkyl, (C3-C8) cycloalkyl (Ci-C8) - alkylamino (Ci-C 8) alkyl, (Ci-C 8) -Haloalkylamino- (Ci-C 8 ) alkyl, (Ci-C 8) - alkylcarbonylamino (Ci-C8) alkyl, (Ci-C8) -Cycloalkylcarbonylamino- (Ci-C8) - alkyl, arylcarbonylamino (Ci-C8) alkyl, Heteroarylcarbonylamino- ( Ci-C8) alkyl, (Ci-C8) alkoxycarbonylamino (Ci-C8) alkyl, (C2-C8) -Alkenyloxycarbonylamino- (Ci-C8) alkyl, aryl (Ci-C 8) alkoxycarbonylamino - (Ci-C8) alkyl, aryl (Ci-C 8) - alkoxycarbonyl [N- (Ci-C8) alkyl] amino (Ci-C8) alkyl, heteroaryl (Ci-C8) - alkoxycarbonylamino - (Ci-C8) alkyl, (C3-C8) cycloalkyl- (Ci-C8) - alkoxycarbonylamino (Ci-C8) alkyl, (C3-C8) -Cycloalkoxycarbonylamino- (Ci-C8) alkyl, aminocarbonylamino - (Ci-C8) alkyl, arylsulfonylamino (Ci-C8) - alkyl, Heteroarylsulfonylamino- (Ci-C8) alkyl, (Ci-C8) alkylsulfonylamino (Ci-C8) alkyl, (C3-C8 ) -Cycloalkylsulfonylamino- (Ci-C 8) alkyl,

Aminoiminoamino-(Ci-C8)-alkyl, Arylsulfonylaminoiminoamino-(Ci-C8)-alkyl, (Ci-C8)-Alkylaminoiminoamino-(Ci-C8)-alkyl steht, für Wasserstoff, Halogen, (Ci-C 8 )-Alkyl, (Ci-C 8 )-Alkoxy, (Ci-C 8 )- Aminoiminoamino- (Ci-C8) alkyl, Arylsulfonylaminoiminoamino- (Ci-C8) alkyl, (Ci-C8) -Alkylaminoiminoamino- (Ci-C8) alkyl, represents hydrogen, halogen, (Ci-C 8) -alkyl , (Ci-C 8) alkoxy, (Ci-C 8) -

Alkoxycarbonyloxy, (C2-C 8 )-Alkenyl, (C 2 -C 8 )-Haloalkenyl, (C 2 -C 8 )-Alkenyl- (Ci-Cs)-alkyl, (C 2 -C 8 )-Alkinyl, (C 2 -C 8 )-Alkinyl-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkyl, Bisaryl-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkoxyaryl-(Ci-C 8 )-alkyl, Aryloxyaryl-(Ci-Cs)- alkyl, (Ci-C 8 )-Alkoxyaryl-(Ci-C 8 )-alkyl, Heteroaryl-(Ci-C 8 )-alkyl, Heterocyclyl- (Ci-Cs)-alkyl, N-(Ci-C 8 )-Alkylheterocyclyl-(Ci-C 8 )-alkyl, N-[(Ci-C 8 )- Alkoxycarbonyl]heterocyclyl-(Ci-C 8 )-alkyl, N-(Aryl-(Ci-C 8 )- alkoxycarbonyl)heterocyclyl-(Ci-C 8 )-alkyl, N-(Arylcarbonyl)heterocyclyl- (Ci-Cs)-alkyl, N-[(Ci-C 8 )-Alkylcarbonyl]heterocyclyl-(Ci-C 8 )-alkyl, N-[(C 3 -C 8 )- Cycloalkylcarbonyl]heterocyclyl-(Ci-C 8 )-alkyl, Cyano-(Ci-C 8 )-alkyl, (Ci-C 8 )- Haloalkyl, (C 3 -C 8 )-Cycloalkyl, (C 3 -C 8 )-Halocycloalkyl, (C 4 -C 8 )-Cycloalkenyl, (C 3 -C 8 )-Cycloalkyl-(Ci-C 8 )-alkyl, (C 3 -C 8 )-Cycloalkenyl-(Ci-C 8 )-alkyl, Hydroxy- (Ci-Cs)-alkyl, (Ci-C 8 )-Alkoxy-(Ci-C 8 )-alkyl, (Ci-C 8 )-Haloalkoxy-(Ci-C 8 )-alkyl, Aryloxy-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkoxy-(Ci-C 8 )-alkyl, Heteroaryl-(Ci-Cs)- alkoxy-(Ci-C 8 )-alkyl, (C 3 -C 8 )-Cycloalkoxy-(Ci-C 8 )-alkyl, (C 3 -C 8 )-Cycloalkyl- (Ci-C 8 )-alkoxy-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkylcarbonyloxy-(Ci-C 8 )-alkyl, Alkoxycarbonyloxy, (C2-C8) -alkenyl, (C 2 -C 8) haloalkenyl, (C 2 -C 8) alkenyl (Ci-Cs) alkyl, (C 2 -C 8) -alkynyl, ( C 2 -C 8) alkynyl (Ci-C 8) alkyl, aryl (Ci-C 8) alkyl, bisaryl (Ci-C 8) alkyl, aryl (Ci-C 8) alkoxyaryl - (Ci-C 8) alkyl, Aryloxyaryl- (Ci-Cs) - alkyl, (Ci-C 8) -Alkoxyaryl- (Ci-C 8) alkyl, heteroaryl (Ci-C 8) alkyl, heterocyclyl - (Ci-Cs) alkyl, N- (Ci-C 8) -Alkylheterocyclyl- (Ci-C 8) -alkyl, N - [(Ci-C8) - alkoxycarbonyl] heterocyclyl (Ci-C 8) - alkyl, N- (aryl (Ci-C8) - alkoxycarbonyl) heterocyclyl- (Ci-C 8) alkyl, N- (arylcarbonyl) heterocyclyl (Ci-Cs) -alkyl, N - [(Ci-C 8 ) alkylcarbonyl] heterocyclyl (Ci-C 8) -alkyl, N - [(C 3 -C 8) - cycloalkylcarbonyl] heterocyclyl (Ci-C8) alkyl, cyano (Ci-C 8) alkyl, (Ci-C 8) - haloalkyl, (C 3 -C 8) cycloalkyl, (C 3 -C 8) halocycloalkyl, (C 4 -C 8) cycloalkenyl, (C 3 -C 8) cycloalkyl ( Ci-C 8) alkyl, (C 3 -C 8) cycloalkenyl (Ci-C 8) -alkyl, hydroxy- (Ci-Cs) alkyl, (Ci-C 8) alkoxy (Ci-C 8) alkyl, (Ci-C 8) haloalkoxy (Ci-C 8) alkyl, aryloxy (Ci-C8) alkyl, aryl (Ci-C 8) alkoxy (Ci-C 8 ) alkyl, heteroaryl (Ci-Cs) - alkoxy- (Ci-C 8) alkyl, (C 3 -C 8) cycloalkoxy (Ci-C 8) alkyl, (C 3 -C 8) - cycloalkyl (Ci-C 8) alkoxy (Ci-C 8) alkyl, (Ci-C8) alkylcarbonyloxy (Ci-C8) alkyl,

Arylcarbonyloxy-(Ci-C 8 )-alkyl, Heteroarylcarbonyloxy-(Ci-C 8 )-alkyl, -(C 3 -C 8 )- Cycloalkylcarbonyloxy-(Ci-C 8 )-alkyl, Arylsulfonyloxy-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkylsulfonyloxy-(Ci-C 8 )-alkyl, Hydrothio-(Ci-C 8 )-alkyl, (Ci-Cs)-Alkylthio- (Ci-Cs)-alkyl, (Ci-C 8 )-Haloalkylthio-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkylthio- (Ci-Cs)-alkyl, -(C 3 -C 8 )-Cycloalkylthio-(Ci-C 8 )-alkyl, Arylthio-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkylsulfinyl-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkylsulfonyl-(Ci-C 8 )-alkyl, (Ci-C 8 )- Haloalkylsulfinyl-(Ci-C 8 )-alkyl, (Ci-C 8 )-Haloalkylsulfonyl-(Ci-C 8 )-alkyl, Aryl- (Ci-C 8 )-alkylsulfinyl-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkylsulfonyl-(Ci-C 8 )-alkyl, (C 3 -C 8 )-Cycloalkylsulfinyl-(Ci-C 8 )-alkyl, (C 3 -C 8 )-Cycloalkylsulfonyl-(Ci-C 8 )- alkyl, Aryl, Heteroaryl, Heterocyclyl, N-[(Ci-C 8 )-Alkyl]heterocyclyl, N-[(Ci-C 8 )- Alkoxycarbonyl]heterocyclyl, N-[Aryl-(Ci-C 8 )-alkoxycarbonyl]heterocyclyl, N- (Arylcarbonyl)heterocyclyl, N-[(Ci-C 8 )-Alkylcarbonyl]heterocyclyl, N-[(Ci-C 8 )- Cycloalkylcarbonyl]heterocyclyl, Hydroxycarbonyl, (Ci-Cs)-Alkoxycarbonyl, (C 3 -C 8 )-Cycloalkoxycarbonyl, (C 3 -C 8 )-Cycloalkyl-(Ci-C 8 )-alkoxycarbonyl, Aryl- (Ci-C 8 )-alkoxycarbonyl, Heteroaryl-(Ci-C 8 )-alkoxycarbonyl, (Ci-C 8 )- Alkylaminocarbonyl, Aminocarbonyl, Bis-(Ci-C 8 )-alkylaminocarbonyl, (C 3 -C 8 )- Cycloalkylaminocarbonyl, Aryl-(Ci-C8)-alkylaminocarbonyl, Arylcarbonyloxy (Ci-C 8) alkyl, Heteroarylcarbonyloxy- (Ci-C 8) alkyl, - (C 3 -C 8) - Cycloalkylcarbonyloxy- (Ci-C 8) alkyl, arylsulfonyloxy (Ci-C 8) alkyl, (Ci-C 8) - alkylsulfonyloxy (Ci-C 8) alkyl, Hydrothio- (Ci-C 8) alkyl, (Ci-Cs) alkylthio (Ci-Cs) alkyl, (C -C 8) -Haloalkylthio- (Ci-C 8) alkyl, aryl (Ci-C8) alkylthio (Ci-Cs) alkyl, - (C 3 -C 8) cycloalkylthio (Ci-C 8) alkyl, arylthio (Ci-C 8) alkyl, (Ci-C8) alkylsulfinyl (Ci-C 8) alkyl, (Ci-C8) alkylsulfonyl (Ci-C 8) - alkyl, (Ci-C 8) - Haloalkylsulfinyl- (Ci-C 8) alkyl, (Ci-C 8) -Haloalkylsulfonyl- (Ci-C 8) alkyl, aryl (Ci-C8) alkylsulfinyl ( Ci-C 8) alkyl, aryl (Ci-C8) alkylsulfonyl (Ci-C 8) alkyl, (C 3 -C 8) -Cycloalkylsulfinyl- (Ci-C 8) alkyl, (C 3 -C 8) -Cycloalkylsulfonyl- (Ci-C 8) - alkyl, aryl, heteroaryl, heterocyclyl, N - [(Ci-C 8) -alkyl] heterocyclyl, N - [(Ci-C8) - alkoxycarbonyl] heterocyclyl, N- [aryl (Ci-C8) -alkoxycarbonyl] heterocyclyl, N- (arylcarbonyl) heterocyclyl, N - [(Ci-C 8) alkylcarbonyl] heterocyclyl, N - [(Ci-C 8) - cycloalkylcarbonyl] heterocyclyl , hydroxycarbonyl, (Ci-Cs) -alkoxycarbonyl, (C 3 -C 8) -cycloalkoxycarbonyl, (C 3 -C 8) cycloalkyl (Ci-C8) alkoxycarbonyl, aryl (Ci-C8) -alkoxycarbonyl , heteroaryl (Ci-C8) alkoxycarbonyl, (Ci-C 8) - alkylaminocarbonyl, aminocarbonyl, bis (Ci-C 8) alkylaminocarbonyl, (C 3 -C 8) - cycloalkylaminocarbonyl, aryl (Ci-C8 ) alkylaminocarbonyl,

Heteroarylaminocarbonyl, Cyano-(Ci-C8)-alkylaminocarbonyl, (Ci-Cs)- Haloalkylaminocarbonyl, (C2-C8)-Alkinyl-(Ci-C8)-alkylaminocarbonyl, Heteroarylaminocarbonyl, cyano (Ci-C8) alkylaminocarbonyl, (Ci-Cs) - Haloalkylaminocarbonyl, (C2-C8) alkynyl (Ci-C8) alkylaminocarbonyl,

Hydroxycarbonyl-(Ci-Ce)-alkyl, (Ci-C 8 )-Alkoxycarbonyl-(Ci-C 8 )-alkyl, (C 3 -C 8 )- Cycloalkoxycarbonyl-(Ci-C8)-alkyl, (C3-C8)-Cycloalkyl-(Ci-C8)-alkoxycarbonyl- (Ci-Ce)-alkyl, Aryl-(Ci-C 8 )-alkoxycarbonyl-(Ci-C 8 )-alkyl, Heteroaryl-(Ci-C 8 )- alkoxycarbonyl-(Ci-C8)-alkyl, (Ci-C8)-Alkylaminocarbonyl-(Ci-C8)-alkyl, Aminocarbonyl-(Ci-C8)-alkyl, Bis-(Ci-C8)-alkylaminocarbonyl-(Ci-C8)-alkyl, (C3-C8)-Cycloalkylaminocarbonyl-(Ci-C 8 )-alkyl, Aryl-(Ci-Ce)- alkylaminocarbonyl-(Ci-C8)-alkyl, Heteroarylaminocarbonyl-(Ci-C8)-alkyl, Cyano-(Ci-C8)-alkylaminocarbonyl-(Ci-C8)-alkyl, (Ci-Ce)- Haloalkylaminocarbonyl-(Ci-C 8 )-alkyl, -(C2-C 8 )-Alkinyl-(Ci-C 8 )- alkylaminocarbonyl-(Ci-C8)-alkyl, Amino-(Ci-C8)-alkyl, (Ci-C8)-Alkylamino- (Ci-Ce)-alkyl, (C2-C 8 )-Alkenylamino-(Ci-C 8 )-alkyl, Arylamino-(Ci-C 8 )-alkyl, Bis- (Ci-C8)-alkylamino-(Ci-C8)-alkyl, Bis-(C3-C8)-cycloalkylamino-(Ci-C8)-alkyl, Aryl-(Ci-C 8 )-alkylamino-(Ci-C 8 )-alkyl, Tns-Aryl-(Ci-C 8 )-alkylamino-(Ci-C 8 )- alkyl, (C3-C8)-Cycloalkylamino-(Ci-C 8 )-alkyl, (C3-C 8 )-Cycloalkyl-(Ci-C 8 )- alkylamino-(Ci-C 8 )-alkyl, (Ci-C 8 )-Haloalkylamino-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkylcarbonylamino-(Ci-C8)-alkyl, (Ci-C8)-Cycloalkylcarbonylamino-(Ci-C8)- alkyl, Arylcarbonylamino-(Ci-C8)-alkyl, Heteroarylcarbonylamino-(Ci-C8)-alkyl, (Ci-C8)-Alkoxycarbonylamino-(Ci-C8)-alkyl, (C2-C8)-Alkenyloxycarbonylamino- (Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkoxycarbonylamino-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )- alkoxycarbonyl[N-(Ci-C8)-alkyl]amino-(Ci-C8)-alkyl, Heteroaryl-(Ci-C8)- alkoxycarbonylamino-(Ci-C8)-alkyl, (C3-C8)-Cycloalkyl-(Ci-C8)- alkoxycarbonylamino-(Ci-C8)-alkyl, (C3-C8)-Cycloalkoxycarbonylamino- (Ci-C8)-alkyl, Aminocarbonylamino-(Ci-C8)-alkyl, Arylsulfonylamino-(Ci-C8)- alkyl, Heteroarylsulfonylamino-(Ci-C8)-alkyl, (Ci-C8)-Alkylsulfonylamino- (Ci-C 8 )-alkyl, (C3-C8)-Cycloalkylsulfonylamino-(Ci-C 8 )-alkyl, Hydroxycarbonyl (Ci-Ce) alkyl, (Ci-C8) alkoxycarbonyl (Ci-C 8) alkyl, (C 3 -C 8) - Cycloalkoxycarbonyl- (Ci-C8) alkyl, (C3-C8 ) cycloalkyl (Ci-C8) alkoxycarbonyl (Ci-Ce) alkyl, aryl (Ci-C8) alkoxycarbonyl (Ci-C 8) alkyl, heteroaryl (Ci-C8) - alkoxycarbonyl - (Ci-C8) alkyl, (Ci-C8) alkylaminocarbonyl (Ci-C8) alkyl, aminocarbonyl (Ci-C8) alkyl, bis (Ci-C8) alkylaminocarbonyl (Ci-C8) alkyl, (C3-C8) -Cycloalkylaminocarbonyl- (Ci-C8) alkyl, aryl (Ci-Ce) - alkylaminocarbonyl (Ci-C8) alkyl, Heteroarylaminocarbonyl- (Ci-C8) alkyl, cyano (Ci-C8) alkylaminocarbonyl (Ci-C8) alkyl, (Ci-Ce) - Haloalkylaminocarbonyl- (Ci-C 8) alkyl, - (C2-C8) alkynyl (Ci-C 8) - alkylaminocarbonyl (Ci-C8) alkyl, amino (Ci-C8) alkyl, (Ci-C8) alkylamino (Ci-Ce) alkyl, (C2-C8) -Alkenylamino- (Ci-C 8 ) alkyl, arylamino (Ci-C 8) alkyl, bis (Ci-C8) alkylamino (Ci-C8) alkyl, bis- (C3-C8) cycloalkylamino (Ci-C8) alkyl , aryl (Ci-C 8) alkylamino (C 8) alkyl, aryl TNS (Ci-C 8) alkylamino (C 8) - alkyl, (C3-C8) cycloalkylamino - (Ci-C 8) alkyl, (C3-C8) cycloalkyl (Ci-C8) - alkylamino (Ci-C 8) alkyl, (Ci-C 8) -Haloalkylamino- (Ci-C 8) alkyl, (Ci-C 8) - alkylcarbonylamino (Ci-C8) alkyl, (Ci-C8) -Cycloalkylcarbonylamino- (Ci-C8) - alkyl, arylcarbonylamino (Ci-C8) alkyl, Heteroarylcarbonylamino- (Ci-C8) alkyl, (Ci-C8) alkoxycarbonylamino (Ci-C8) alkyl, (C2-C8) -Alkenyloxycarbonylamino- (Ci-C8) alkyl, aryl (Ci-C 8) - alkoxycarbonylamino (Ci-C8) alkyl, aryl (Ci-C 8) - alkoxycarbonyl [N- (Ci-C8) alkyl] amino (Ci-C8) alkyl, heteroaryl (Ci-C8) - alkoxycarbonylamino (Ci-C8) alkyl, (C3-C8) cycloalkyl- (Ci-C8) - alkoxycarbonylamino (Ci-C8) alkyl, (C3-C8) -Cycloalkoxycarbonylamino- (Ci-C8) alkyl, aminocarbonylamino (Ci-C8) alkyl, arylsulfonylamino (Ci-C8) - alkyl, Heteroarylsulfonylamino- (Ci-C8) alkyl, (Ci-C8) alkylsulfonylamino (Ci-C8) alkyl, (C3 C8) -Cycloalkylsulfonylamino- (Ci-C 8) alkyl,

Aminoiminoamino-(Ci-C8)-alkyl, Arylsulfonylaminoiminoamino-(Ci-C8)-alkyl, (Ci-C8)-Alkylaminoiminoamino-(Ci-C8)-alkyl steht, R 6 und R 8 unabhängig voneinander für H, (Ci-Ce)-Alkyl, (C 2 -C 8 )-Alkenyl-(Ci-C 8 )- alkyl, (C2-C 8 )-Alkinyl-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkyl, (C 3 -C 8 )-Cycloalkyl, (C 3 -C 8 )-Cycloalkyl-(Ci-C 8 )-alkyl, Heterocyclyl, Heterocyclyl-(Ci-C 8 )-alkyl, Amino-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkoxy-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkylthio-(Ci-C 8 )- alkyl, (Ci-Cs)-Haloalkyl, (Ci-C 8 )-Alkylamino-(Ci-C 8 )-alkyl, Bis-(Ci-Cs)- alkylamino-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkylcarbonylamino-(Ci-C 8 )-alkyl, (C 3 -C 8 )- Cycloalkylcarbonylamino-(Ci-C 8 )-alkyl, Arylcarbonylamino-(Ci-C 8 )-alkyl, Aminoiminoamino- (Ci-C8) alkyl, Arylsulfonylaminoiminoamino- (Ci-C8) alkyl, (Ci-C8) -Alkylaminoiminoamino- (Ci-C8) -alkyl, R 6 and R 8 are each independently H, (Ci- Ce) alkyl, (C 2 -C 8) alkenyl (Ci-C 8) - alkyl, (C2-C8) alkynyl (Ci-C 8) alkyl, aryl (Ci-C 8) alkyl, (C 3 -C 8) -cycloalkyl, (C 3 -C 8) cycloalkyl (Ci-C 8) alkyl, heterocyclyl, heterocyclyl (Ci-C8) alkyl, amino (Ci- C 8) alkyl, (Ci-C 8) alkoxy (Ci-C 8) alkyl, (Ci-C8) alkylthio (Ci-C 8) - alkyl, (Ci-Cs) -haloalkyl, (Ci-C 8) alkylamino (Ci-C8) alkyl, bis (Ci-Cs) - alkylamino (Ci-C 8) alkyl, (Ci-C8) -alkylcarbonylamino- (Ci-C 8) -alkyl, (C 3 -C 8) - Cycloalkylcarbonylamino- (Ci-C 8) alkyl, arylcarbonylamino (Ci-C 8) alkyl,

(Ci-C 8 )-Alkoxycarbonylamino-(Ci-C 8 )-alkyl, Aryl-(Ci-C 8 )-alkoxycarbonylamino (Ci-C 8 )-alkyl, (C3-C 8 )-Cycloalkyl-(Ci-C 8 )-alkoxycarbonylamino-(Ci-C 8 )-alkyl, Aminocarbonylamino-(Ci-C 8 )-alkyl, Aminoiminoamino-(Ci-C 8 )-alkyl, (Ci-C8) alkoxycarbonylamino (Ci-C 8) alkyl, aryl (Ci-C8) alkoxycarbonylamino (Ci-C 8) alkyl, (C3-C8) cycloalkyl (Ci-C 8) alkoxycarbonylamino (Ci-C 8) alkyl, aminocarbonylamino (Ci-C 8) alkyl, Aminoiminoamino- (Ci-C 8) alkyl,

Arylsulfonylaminoiminoamino-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkylaminoiminoamino- (Ci-Cs)-alkyl stehen, Arylsulfonylaminoiminoamino- (Ci-C8) alkyl, (Ci-C 8) -Alkylaminoiminoamino- (Ci-Cs) alkyl,

R 41 für H, (Ci-C 8 )-Alkyl, (C 2 -C 8 )-Alkenyl-(Ci-C 8 )-alkyl, (C 2 -C 8 )-Alkinyl, (Ci-C 8 )- Alkylcarbonyl, (C3-C 8 )-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl, (Ci-C 8 )-Alkoxycarbonyl, Aryl-(Ci-C 8 )-alkoxycarbonyl, (C3-C 8 )- Cycloalkoxycarbonyl, (C3-C 8 )-Cycloalkyl-(Ci-C 8 )-alkoxycarbonyl, (Ci-C 8 )- Alkylsulfonyl, (C 3 -C 8 )-Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C 8 )- Alkoxycarbonylcarbonyl, Aryl-(Ci-C 8 )-alkoxycarbonylcarbonyl, (Ci-C 8 )- Alkylaminothiocarbonyl, (Ci-Cs)-Alkylaminocarbonyl, Aryl-(Ci-C 8 )-alkyl, Hetaroaryl-(Ci-C 8 )-alkyl, Cyano-(Ci-C 8 )-alkyl, (Ci-Cs)-Haloalkyl, (C 3 -C 8 )- Cycloalkyl, (C 3 -C 8 )-Cycloalkyl-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkoxy-(Ci-C 8 )-alkyl, R 41 is H, (Ci-C 8) -alkyl, (C 2 -C 8) alkenyl (Ci-C 8) alkyl, (C 2 -C 8) alkynyl, (Ci-C 8) - alkylcarbonyl, (C3-C8) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl, (Ci-C8) -alkoxycarbonyl, aryl (Ci-C8) -alkoxycarbonyl, (C3-C8) - cycloalkoxycarbonyl, (C3-C8) cycloalkyl (Ci-C8) alkoxycarbonyl, (Ci-C 8) - alkylsulfonyl, (C 3 -C 8) cycloalkylsulfonyl, arylsulfonyl, (Ci-C 8) - alkoxycarbonylcarbonyl, aryl (Ci-C 8) -alkoxycarbonylcarbonyl, (Ci-C 8) - alkylaminothiocarbonyl, (Ci-Cs) alkylaminocarbonyl, aryl (Ci-C 8) alkyl, Hetaroaryl- (Ci-C 8) -alkyl, cyano- (Ci-C 8) alkyl, (Ci-Cs) -haloalkyl, (C 3 -C 8) - cycloalkyl, (C 3 -C 8) cycloalkyl (Ci-C 8) alkyl, (Ci-C 8) alkoxy ( Ci-C 8) alkyl,

(Ci-C 8 )-Haloalkoxy-(Ci-C 8 )-alkyl, (C 2 -C 8 )-Alkinyl-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkoxycarbonyl-(Ci-C 8 )-alkyl, Aminocarbonyl-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkylaminocarbonyl-(Ci-C 8 )-alkyl, Bis-(Ci-C 8 )-alkylaminocarbonyl-(Ci-C 8 )-alkyl steht, (Ci-C 8) haloalkoxy (Ci-C 8) alkyl, (C 2 -C 8) alkynyl (Ci-C 8) alkyl, (Ci-C8) - alkoxycarbonyl (Ci-C 8) alkyl, aminocarbonyl (Ci-C 8) alkyl, (Ci-C 8) - alkylaminocarbonyl (Ci-C8) alkyl, bis (Ci-C 8) alkylaminocarbonyl (Ci-C 8 ) -alkyl,

im Falle der Gruppierung Q-21 ausschließlich für H oder Methyl steht in the case of the group Q-21 is available exclusively for H or methyl

R 42 für (C 2 -C 8 )-Alkyl, (C 2 -C 8 )-Alkenyl-(Ci-C 8 )-alkyl, (C 2 -C 8 )-Alkinyl, (Ci-C 8 )- R 42 is (C 2 -C 8) alkyl, (C 2 -C 8) alkenyl (Ci-C 8) alkyl, (C 2 -C 8) alkynyl, (Ci-C 8) -

Alkylcarbonyl, (C3-C 8 )-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl, (Ci-C 8 )-Alkoxycarbonyl, Aryl-(Ci-C 8 )-alkoxycarbonyl, (C3-C 8 )- Cycloalkoxycarbonyl, (C3-C 8 )-Cycloalkyl-(Ci-C 8 )-alkoxycarbonyl, (Ci-C 8 )- Alkylsulfonyl, (C 3 -C 8 )-Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C 8 )- Alkoxycarbonylcarbonyl, Aryl-(Ci-C8)-alkoxycarbonylcarbonyl, (Ci-C 8 )- Alkylaminothiocarbonyl, (Ci-C8)-Alkylaminocarbonyl, Aryl-(Ci-C8)-alkyl, Hetaroaryl-(Ci-C 8 )-alkyl, Cyano-(Ci-C 8 )-alkyl, (Ci-C 8 )-Haloalkyl, (C 3 -C 8 )- Cycloalkyl, (C 3 -C 8 )-Cycloalkyl-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkoxy-(Ci-C 8 )-alkyl, Alkylcarbonyl, (C3-C8) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl, (Ci-C8) -alkoxycarbonyl, aryl (Ci-C8) -alkoxycarbonyl, (C3-C8) - cycloalkoxycarbonyl, (C3-C8) cycloalkyl (Ci-C8) alkoxycarbonyl, (Ci-C 8) - alkylsulfonyl, (C 3 -C 8) cycloalkylsulfonyl, arylsulfonyl, (Ci-C 8) - alkoxycarbonylcarbonyl, aryl (Ci-C8) - alkoxycarbonylcarbonyl, (Ci-C 8) - alkylaminothiocarbonyl, (Ci-C8) alkylaminocarbonyl, aryl (Ci-C8) alkyl, Hetaroaryl- (Ci-C8) alkyl, cyano (C 8) alkyl , (Ci-C8) -haloalkyl, (C 3 -C 8) - cycloalkyl, (C 3 -C 8) cycloalkyl (Ci-C 8) alkyl, (Ci-C 8) alkoxy (Ci -C 8) alkyl,

(Ci-C 8 )-Haloalkoxy-(Ci-C 8 )-alkyl, (C 2 -C 8 )-Alkinyl-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkoxycarbonyl-(Ci-C 8 )-alkyl, Aminocarbonyl-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkylaminocarbonyl-(Ci-C 8 )-alkyl, Bis-(Ci-C 8 )-alkylaminocarbonyl-(Ci-C 8 )-alkyl steht, (Ci-C 8) haloalkoxy (Ci-C 8) alkyl, (C 2 -C 8) alkynyl (Ci-C 8) alkyl, (Ci-C8) - alkoxycarbonyl (Ci-C 8) alkyl, aminocarbonyl (Ci-C 8) alkyl, (Ci-C 8) - alkylaminocarbonyl (Ci-C8) alkyl, bis (Ci-C 8) alkylaminocarbonyl (Ci-C 8 ) -alkyl,

R 43 für H oder Methyl steht, R 43 is H or methyl,

R 44 für Wasserstoff, (Ci-Cs)-Alkyl, (C 2 -C 8 )-Alkenyl-(Ci-C 8 )-alkyl, (C 2 -C 8 )-Alkinyl, (Ci-C 8 )-Alkylcarbonyl, (C3-C 8 )-Cycloalkylcarbonyl, Arylcarbonyl, R 44 is hydrogen, (Ci-Cs) alkyl, (C 2 -C 8) alkenyl (Ci-C 8) alkyl, (C 2 -C 8) alkynyl, (Ci-C 8) alkylcarbonyl , (C3-C8) cycloalkylcarbonyl, arylcarbonyl,

Heteroarylcarbonyl, (Ci-Cs)-Alkoxycarbonyl, Aryl-(Ci-C 8 )-alkoxycarbonyl, Heteroarylcarbonyl, (Ci-Cs) alkoxycarbonyl, aryl (Ci-C8) -alkoxycarbonyl,

(C3-C 8 )-Cycloalkoxycarbonyl, (C3-C 8 )-Cycloalkyl-(Ci-C 8 )-alkoxycarbonyl, (C3-C8) cycloalkoxycarbonyl, (C3-C8) cycloalkyl- (Ci-C8) -alkoxycarbonyl,

(Ci-Cs)-Alkylsulfonyl, (C 3 -C 8 )-Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C 8 )- Alkoxycarbonylcarbonyl, Aryl-(Ci-C 8 )-alkoxycarbonylcarbonyl, (Ci-C 8 )- Alkylaminothiocarbonyl, (Ci-Cs)-Alkylaminocarbonyl, Aryl-(Ci-C 8 )-alkyl, Hetaroaryl-(Ci-C 8 )-alkyl, Cyano-(Ci-C 8 )-alkyl, (Ci-Cs)-Haloalkyl, (C 3 -C 8 )- Cycloalkyl, (C 3 -C 8 )-Cycloalkyl-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkoxy-(Ci-C 8 )-alkyl, (Ci-Cs) alkylsulfonyl, (C 3 -C 8) cycloalkylsulfonyl, arylsulfonyl, (Ci-C 8) - alkoxycarbonylcarbonyl, aryl (Ci-C 8) -alkoxycarbonylcarbonyl, (Ci-C 8) - alkylaminothiocarbonyl, ( Ci-Cs) alkylaminocarbonyl, aryl (Ci-C 8) alkyl, Hetaroaryl- (Ci-C 8) -alkyl, cyano- (Ci-C 8) alkyl, (Ci-Cs) -haloalkyl, (C 3 -C 8) - cycloalkyl, (C 3 -C 8) cycloalkyl (Ci-C 8) alkyl, (Ci-C 8) alkoxy (Ci-C 8) alkyl,

(Ci-C 8 )-Haloalkoxy-(Ci-C 8 )-alkyl, (C 2 -C 8 )-Alkinyl-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkoxycarbonyl-(Ci-C 8 )-alkyl, Aminocarbonyl-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkylaminocarbonyl-(Ci-C 8 )-alkyl, Bis-(Ci-C 8 )-alkylaminocarbonyl-(Ci-C 8 )-alkyl steht, (Ci-C 8) haloalkoxy (Ci-C 8) alkyl, (C 2 -C 8) alkynyl (Ci-C 8) alkyl, (Ci-C8) - alkoxycarbonyl (Ci-C 8) alkyl, aminocarbonyl (Ci-C 8) alkyl, (Ci-C 8) - alkylaminocarbonyl (Ci-C8) alkyl, bis (Ci-C 8) alkylaminocarbonyl (Ci-C 8 ) -alkyl,

R 51 und R 71 unabhängig voneinander für Wasserstoff und Methyl stehen, R 53 für Methyl steht, R 51 and R 71 independently represent hydrogen and methyl, R 53 is methyl,

R 61 und R 81 unabhängig voneinander für Wasserstoff und Methyl stehen, R 63 für H, Methyl steht R 61 and R 81 independently of one another represent hydrogen and methyl, R 63 is H, methyl

R 54 , R 64 , R 74 , R 84 unabhängig voneinander für Wasserstoff, Methyl stehen, wobei mindestens eine der Gruppen R 54 , R 64 , R 74 , R 84 für Methyl stehen muß, R 54, R 64, R 74, R 84 are independently hydrogen, methyl, where at least one of R 54, R 64, R 74, R 84 must be methyl,

V für Hydroxycarbonyl, (Ci-C8)-Alkoxycarbonyl, (C3-C8)-Cycloalkoxycarbonyl, (C3-C8)-Cycloalkyl-(Ci-C8)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-Cs)- alkoxycarbonyl, Aminocarbonyl, (Ci-C8)-Alkylaminocarbonyl, Bis-(Ci-Cs)- alkylaminocarbonyl, (Ci-C8)-Alkyl[(Ci-C8)-Alkoxy]aminocarbonyl, (C3-C8)- Cycloalkylaminocarbonyl, Aryl-(Ci-C8)-alkylaminocarbonyl, Heteroaryl-(Ci-C8) alkylaminocarbonyl, Cyano-(Ci-C8)-alkylaminocarbonyl, (Ci-Cs)- Haloalkylaminocarbonyl, (C2-C8)-Alkinyl-(Ci-C8)-alkylaminocarbonyl, (Ci-Cs)- Alkoxycarbonyl-(Ci-C8)-alkylaminocarbonyl, Hydroxycarbonyl-(Ci-C8)- alkylaminocarbonyl, Aminocarbonyl-(Ci-C8)-alkylaminocarbonyl, (Ci-Cs)- Alkylaminocarbonyl-(Ci-C8)-alkylaminocarbonyl, (C3-C8)- Cycloalkylaminocarbonyl-(Ci-C8)-alkylaminocarbonyl, (C3-C8)-Cycloalkyl- (Ci-C8)-alkylaminocarbonyl steht, m für O, 1 , 2, 3, 4, 5 steht, p für 1 , 2, 3, 4 steht, V hydroxycarbonyl, (Ci-C8) -alkoxycarbonyl, (C3-C8) cycloalkoxycarbonyl, (C3-C8) cycloalkyl- (Ci-C8) alkoxycarbonyl, aryloxycarbonyl, aryl (Ci-Cs) - alkoxycarbonyl, aminocarbonyl, (Ci-C8) alkylaminocarbonyl, bis (Ci-Cs) - alkylaminocarbonyl, (Ci-C8) alkyl [(Ci-C8) -alkoxy] aminocarbonyl, (C3-C8) - cycloalkylaminocarbonyl, aryl (Ci-C8 ) alkylaminocarbonyl, heteroaryl (Ci-C8) alkylaminocarbonyl, cyano (Ci-C8) alkylaminocarbonyl, (Ci-Cs) - Haloalkylaminocarbonyl, (C2-C8) alkynyl (Ci-C8) alkylaminocarbonyl, (Ci Cs) - alkoxycarbonyl (Ci-C8) alkylaminocarbonyl, hydroxycarbonyl (Ci-C8) - alkylaminocarbonyl, aminocarbonyl (Ci-C8) alkylaminocarbonyl, (Ci-Cs) - alkylaminocarbonyl (Ci-C8) alkylaminocarbonyl, ( C3-C8) - cycloalkylaminocarbonyl (Ci-C8) alkylaminocarbonyl, (C3-C8) cycloalkyl- (Ci-C8) alkylaminocarbonyl, m is O, 1, 2, 3, 4, 5, p is 1 , 2, 3, 4 is,

Y für Cyano, Cyano-(Ci-C 8 )-alkyl, Hydroxy-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkoxy-(Ci-C 8 ) alkyl, Hydroxycarbonyl, (Ci-C8)-Alkoxycarbonyl, (C3-C8)-Cycloalkoxycarbonyl, (C3-C8)-Cycloalkyl-(Ci-C8)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-Cs)- alkoxycarbonyl, Aminocarbonyl, (Ci-C8)-Alkylaminocarbonyl, Bis-(Ci-Cs)- alkylaminocarbonyl, (Ci-C8)-Alkyl[(Ci-C8)-Alkoxy]aminocarbonyl, (C3-C8)- Cycloalkylaminocarbonyl, Aryl-(Ci-C8)-alkylaminocarbonyl, Heteroaryl-(Ci-Cs) alkylaminocarbonyl, Cyano-(Ci-C8)-alkylaminocarbonyl, (Ci-Cs)- Haloalkylaminocarbonyl, (C2-C8)-Alkinyl-(Ci-C8)-alkylaminocarbonyl, (Ci-Cs)- Alkoxycarbonylaminocarbonyl, Aryl-(Ci-C8)-alkoxycarbonylaminocarbonyl, Hydroxycarbonyl-(Ci-C 8 )-alkyl, (Ci-C 8 )-Alkoxycarbonyl-(Ci-C 8 )-alkyl, (C 3 -C 8 )- Cycloalkoxycarbonyl-(Ci-C8)-alkyl, (C3-C8)-Cycloalkyl-(Ci-C8)-alkoxycarbonyl- (Ci-C8)-alkyl, (Ci-C8)-Alkylaminocarbonyl-(Ci-C8)-alkyl, Aminocarbonyl- (Ci-Ce)-alkyl, Bis-(Ci-C 8 )-alkylaminocarbonyl-(Ci-C 8 )-alkyl, (C 3 -C 8 )- Cycloalkylaminocarbonyl-(Ci-C8)-alkyl, Aryl-(Ci-C8)-alkylaminocarbonyl- (Ci-C8)-alkyl, Heteroaryl-(Ci-C8)-alkylaminocarbonyl-(Ci-C8)-alkyl, Cyano- (Ci-C8)-alkylaminocarbonyl-(Ci-C8)-alkyl, (Ci-C8)-Haloalkylaminocarbonyl- (Ci-Ce)-alkyl, (C2-C8)-Alkinyl-(Ci-C8)-alkylaminocarbonyl-(Ci-C 8 )-alkyl, (C3-C8)-Cycloalkyl-(Ci-C8)-alkylaminocarbonyl-(Ci-C 8 )-alkyl, (Ci-C 8 )- Alkoxycarbonylaminocarbonyl-(Ci-C8)-alkyl, Aryl-(Ci-Cs)- alkoxycarbonylaminocarbonyl-(Ci-C8)-alkyl, Y is cyano, cyano (Ci-C 8) alkyl, hydroxy (Ci-C 8) alkyl, (Ci-C 8) alkoxy (Ci-C 8) alkyl, hydroxycarbonyl, (Ci-C8) alkoxycarbonyl, (C3-C8) cycloalkoxycarbonyl, (C3-C8) cycloalkyl- (Ci-C8) alkoxycarbonyl, aryloxycarbonyl, aryl (Ci-Cs) - alkoxycarbonyl, aminocarbonyl, (Ci-C8) alkylaminocarbonyl, Up - (Ci-Cs) - alkylaminocarbonyl, (Ci-C8) alkyl [(Ci-C8) -alkoxy] aminocarbonyl, (C3-C8) - cycloalkylaminocarbonyl, aryl (Ci-C8) alkylaminocarbonyl, heteroaryl- (Ci Cs) alkylaminocarbonyl, cyano (Ci-C8) alkylaminocarbonyl, (Ci-Cs) - Haloalkylaminocarbonyl, (C2-C8) alkynyl (Ci-C8) alkylaminocarbonyl, (Ci-Cs) - Alkoxycarbonylaminocarbonyl, aryl (Ci C8) -alkoxycarbonylaminocarbonyl, hydroxycarbonyl- (Ci-C 8) alkyl, (Ci-C8) alkoxycarbonyl (Ci-C 8) alkyl, (C 3 -C 8) - Cycloalkoxycarbonyl- (Ci-C8) alkyl, (C3-C8) cycloalkyl- (Ci-C8) -alkoxycarbonyl (Ci-C8) alkyl, (Ci-C8) alkylaminocarbonyl (Ci-C8) alkyl, aminocarbonyl (Ci-Ce) -alkyl, bis- (Ci-C 8) alkylaminocarbonyl (Ci-C8) alkyl, (C 3 -C 8) - cycloalkylaminocarbonyl (Ci-C8) alkyl, aryl (Ci-C8) alkylaminocarbonyl - (Ci-C8) alkyl, heteroaryl (Ci-C8) alkylaminocarbonyl (Ci-C8) alkyl, cyano (Ci-C8) alkylaminocarbonyl (Ci-C8) alkyl, (Ci-C8) -Haloalkylaminocarbonyl- (Ci-Ce) alkyl, (C2-C8) alkynyl (Ci-C8) alkylaminocarbonyl (Ci-C8) alkyl, (C3-C8) cycloalkyl- (Ci-C8) - alkylaminocarbonyl (Ci-C 8) alkyl, (Ci-C 8) - Alkoxycarbonylaminocarbonyl- (Ci-C8) alkyl, aryl (Ci-Cs) - alkoxycarbonylaminocarbonyl- (Ci-C8) alkyl,

(Ci-C8)-Alkoxycarbonyl-(Ci-C8)-alkylaminocarbonyl, Hydroxycarbonyl-(Ci-C8)- alkylaminocarbonyl, Aminocarbonyl-(Ci-C8)-alkylaminocarbonyl, (Ci-Cs)- Alkylaminocarbonyl-(Ci-C8)-alkylaminocarbonyl, (C3-C8)- Cycloalkylaminocarbonyl-(Ci-C8)-alkylaminocarbonyl, (C3-C8)-Cycloalkyl- (Ci-C8)-alkylaminocarbonyl, (C3-C8)-Cycloalkyl-(Ci-C8)-alkylaminocarbonyl- (Ci-C8)-alkyl, (C2-C8)-Alkenyloxycarbonyl, (C2-C8)-Alkenyloxycarbonyl-(Ci-C8) alkyl, (C2-C 8 )-Alkenylaminocarbonyl, (C2-C 8 )-Alkenyl-(Ci-C 8 )- alkylaminocarbonyl, (C2-C8)-Alkenylaminocarbonyl-(Ci-C8)-alkyl, (C2-C8)- Alkenyl-(Ci-C8)-alkylaminocarbonyl-(Ci-C8)-alkyl steht (Ci-C8) -alkoxycarbonyl (Ci-C8) alkylaminocarbonyl, hydroxycarbonyl (Ci-C8) - alkylaminocarbonyl, aminocarbonyl (Ci-C8) alkylaminocarbonyl, (Ci-Cs) - alkylaminocarbonyl (Ci-C8) - alkylaminocarbonyl, (C3-C8) - cycloalkylaminocarbonyl (Ci-C8) alkylaminocarbonyl, (C3-C8) cycloalkyl- (Ci-C8) alkylaminocarbonyl, (C3-C8) cycloalkyl- (Ci-C8) -alkylaminocarbonyl- (Ci-C8) alkyl, (C2-C8) alkenyloxycarbonyl, (C2-C8) -Alkenyloxycarbonyl- (Ci-C8) alkyl, (C2-C8) -Alkenylaminocarbonyl, (C2-C8) -alkenyl ( Ci-C 8) - alkylaminocarbonyl, (C2-C8) -Alkenylaminocarbonyl- (Ci-C8) alkyl, (C2-C8) - alkenyl (Ci-C8) alkylaminocarbonyl (Ci-C8) alkyl

Die Verbindungen der Formel (I) können Salze bilden. The compounds of formula (I) can form salts. Salzbildung kann durch Einwirkung einer Base auf solche Verbindungen der Formel (I) erfolgen, die ein acides Wasserstoffatom tragen, z. B. im Falle dass Y eine COOH-Gruppe enthält. Salt formation can take place by the action of a base on those compounds of formula (I) carrying an acidic hydrogen atom, for. Example, in the case that Y contains a COOH group. Geeignete Basen sind beispielsweise organische Amine, wie Trialkylamine, Suitable bases include organic amines such as trialkylamines,

Morpholin, Piperidin oder Pyridin sowie Ammonium-, Alkali- oder Morpholine, piperidine, or pyridine, and ammonium, alkali or

Erdalkalimetallhydroxide, -carbonate und -hydrogencarbonate, insbesondere Alkaline earth metal hydroxides, carbonates and bicarbonates, in particular

Natrium- und Kaliumhydroxid, Natrium- und Kaliumcarbonat und Natrium und Kaliumhydrogencarbonat. Sodium and potassium hydroxides, sodium and potassium carbonate and sodium and potassium bicarbonate. Diese Salze sind Verbindungen, in denen der acide Wasserstoff durch ein für die Landwirtschaft geeignetes Kation ersetzt wird, beispielsweise Metallsalze, insbesondere Alkalimetallsalze oder These salts are compounds wherein the acidic hydrogen is replaced by an agriculturally suitable cation, for example metal salts, in particular alkali metal salts or

Erdalkalimetallsalze, insbesondere Natrium- und Kaliumsalze, oder auch Alkaline earth metal salts, in particular sodium and potassium salts, or else

Ammoniumsalze, Salze mit organischen Aminen oder quartäre (quaternäre) Ammoniumsalze, zum Beispiel mit Kationen der Formel [NRR ' R " R " ' ] + , worin R bis R ' " jeweils unabhängig voneinander einen organischen Rest, insbesondere Alkyl, Aryl, Aralkyl oder Alkylaryl darstellen. Infrage kommen auch Alkylsulfonium- und Alkylsulfoxoniumsalze, wie (Ci-C4)-Trialkylsulfonium- und (C1-C4)- Trialkylsulfoxoniumsalze. Ammonium salts, salts with organic amines or quaternary (quaternary) ammonium salts, for example with cations of formula [NRR 'R "R"'] + wherein R to R '"each independently represents an organic radical, in particular alkyl, aryl, aralkyl or . alkylaryl represent questioning come alkylsulfonium and Alkylsulfoxoniumsalze as (Ci-C4) -Trialkylsulfonium- and (C1-C4) - trialkylsulfoxonium.

Die Verbindungen der Formel (I) können durch Anlagerung einer geeigneten anorganischen oder organischen Säure, wie beispielsweise Mineralsäuren, wie beispielsweise HCl, HBr, H2SO4, H3PO 4 oder HNO3, oder organische Säuren, z. B. Carbonsäuren, wie Ameisensäure, Essigsäure, Propionsäure, Oxalsäure, Milchsäure oder Salicylsäure oder Sulfonsäuren, wie zum Beispiel p-Toluolsulfonsäure, an eine basische Gruppe, wie z. B. Amino, Alkylamino, Dialkylamino, Piperidino, Morpholino oder Pyridino, Salze bilden. The compounds of formula (I) can be prepared by addition of a suitable inorganic or organic acid, such as mineral acids, such as HCl, HBr, H2SO4, H3PO 4 or HNO 3, or organic acids, for. Example, carboxylic acids such as formic acid, acetic acid, propionic acid , form oxalic acid, lactic acid or salicylic acid, or sulfonic acids, such as p-toluenesulfonic acid, to a basic group, such as. for example, amino, alkylamino, dialkylamino, piperidino, morpholino or pyridino salts. Diese Salze enthalten dann die konjugierte Base der Säure als Anion. These salts then contain the conjugated base of the acid as anion.

Geeignete Substituenten, die in deprotonierter Form, wie z. B. Sulfonsäuren oder Carbonsäuren, vorliegen, können innere Salze mit ihrerseits protonierbaren Suitable substituents which are present in deprotonated form, such as. For example, sulfonic acids or carboxylic acids, can form internal salts with turn protonatable

Gruppen, wie Aminogruppen bilden. Groups, such as amino groups. Im Folgenden werden die erfindungsgemäß verwendeten Verbindungen der Formel (I) und ihre Salze als "Verbindungen der allgemeinen Formel (I)" bezeichnet. In the following, the compounds used in the invention of the formula (I) and their salts as "compounds of the general formula (I)" are referred to.

Bevorzugt ist die erfindungsgemäße Verwendung von Verbindungen der allgemeinen Formel (I), Preferably, the inventive use of compounds of general formula (I) is

Figure imgf000020_0001
zur Toleranzerhöhung gegenüber abiotischem Stress in Pflanzen, worin Q für die Gruppierungen to increase tolerance to abiotic stress in plants, where Q represents the groups
Figure imgf000021_0001

Q-1 Q-20 Q-21 Q-1 Q-20 Q-21

Figure imgf000021_0002

Q-22 Q-23 Q-24 steht, und wobei die Reste R 4 bis R 8 , und R 41 bis R 84 sowie Y und m und p jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zum Schwefelatom der S0 2 -Gruppe steht; Q-22 Q-23 Q-24 is, and where the radicals R 4 to R 8 and R 41 to R 84 and Y and m and p are each as defined in accordance with the following definitions and where the arrow represents a bond to the sulfur atom the S0 2 group;

A 2 , A 3 gleich oder verschieden sind und unabhängig voneinander für N A 2, A 3 are identical or different and are each independently N

(Stickstoff) oder die Gruppierung CW stehen, wobei jedoch in keinem Fall mehr als zwei N-Atome benachbart sind, und wobei W in der Gruppierung C- Wjeweils gleiche oder verschiedene Bedeutungen gemäß der (Nitrogen) or the group CW are, but in no case more than two N atoms are adjacent, and wherein W in the group C- Wjeweils identical or different meanings in accordance with the

nachstehenden Definition hat, jeweils für Wasserstoff, Nitro, Amino, Cyano, Thiocyanato, Isothiocyanato, Halogen, (Ci-Ce)-Alkyl, (C 3 -C 6 )-Cycloalkyl, (C 2 -C 6 )-Alkenyl, (C 2 -C 6 )-Alkinyl, Aryl, Aryl-(Ci-C 6 )-alkyl, Aryl-(Ci-C 6 )-alkoxy, Heteroaryl, (Ci-C 6 )-Alkoxy- (Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkyl, (C 3 -C 6 )-Halocycloalkyl, (Ci-C 6 )-Alkoxy, Definition below, has, in each case represent hydrogen, nitro, amino, cyano, thiocyanato, isothiocyanato, halogen, (Ci-Ce) alkyl, (C 3 -C 6) -cycloalkyl, (C 2 -C 6) alkenyl, (C 2 -C 6) -alkynyl, aryl, aryl- (Ci-C 6) alkyl, aryl (Ci-C 6) alkoxy, heteroaryl, (Ci-C 6) alkoxy (Ci-C 6) - alkyl, (Ci-C 6) -haloalkyl, (C 3 -C 6) halocycloalkyl, (Ci-C 6) alkoxy,

(Ci-C6)-Haloalkoxy, Aryloxy, Heteroaryloxy, (C3-C6)-Cycloalkyloxy, (C3-C6)- Cycloalkyl-(Ci-C6)-alkoxy, (Ci-C6)-Alkoxycarbonyl, (Ci-C6)-Alkoxycarbonyl- (Ci-C6) haloalkoxy, aryloxy, heteroaryloxy, (C3-C6) -cycloalkyloxy, (C3-C6) - cycloalkyl (Ci-C6) -alkoxy, (Ci-C6) -alkoxycarbonyl, (Ci-C6) - alkoxycarbonyl

(Ci-C6)-alkyl, Hydroxycarbonyl, Aminocarbonyl, (Ci-C6)-Alkylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Cyano-(Ci-C6)-alkylaminocarbonyl, (C2-C6)- Alkenylaminocarbonyl, (C2-C6)-Alkinylaminocarbonyl, (Ci-C6)-Alkylamino, (Ci-C 6 )-Alkylthio, (Ci-C 6 )-Haloalkylthio, Bis-(Ci-C 6 )-alkylamino, (C 3 -C 6 )- Cycloalkylamino, (Ci-C6)-Alkylcarbonylamino, (C3-C6)- (Ci-C6) alkyl, hydroxycarbonyl, aminocarbonyl, (Ci-C6) alkylaminocarbonyl, (C3-C6) cycloalkylaminocarbonyl, cyano (Ci-C6) alkylaminocarbonyl, (C2-C6) - alkenylaminocarbonyl, (C2-C6 ) -Alkinylaminocarbonyl, (Ci-C6) alkylamino, (Ci-C 6) alkylthio, (Ci-C 6) haloalkylthio, bis (Ci-C 6) alkylamino, (C 3 -C 6) - cycloalkylamino , (Ci-C6) alkylcarbonylamino, (C3-C6) -

Cycloalkylcarbonylamino, Formylamino, (Ci-C6)-Haloalkylcarbonylamino, (Ci-C6)-Alkoxycarbonylamino, (Ci-C6)-Alkylaminocarbonylamino, Bis-[(Ci-C6)- Alkyl]-aminocarbonyl-amino, (Ci-C6)-Alkylsulfonylamino, (C3-C6)- Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl- (Ci-C6)-haloalkylamino, Amino-(Ci-C6)-alkylsulfonyl, Amino-(Ci-C6)- haloalkylsulfonyl, (Ci-C6)-Alkylsulfonyl, (C3-C6)-Cycloalkylsulfonyl, Cycloalkylcarbonylamino, formylamino, (Ci-C6) -Haloalkylcarbonylamino, (Ci-C6) alkoxycarbonylamino, (Ci-C6) alkylaminocarbonylamino, bis - [(Ci-C6) - alkyl] aminocarbonyl-amino, (Ci-C6) - alkylsulfonylamino, (C3-C6) - cycloalkylsulfonylamino, arylsulfonylamino, Hetarylsulfonylamino, sulfonyl (Ci-C6) -haloalkylamino, amino (Ci-C6) alkylsulfonyl, amino (Ci-C6) - haloalkylsulfonyl, (Ci-C6) - alkylsulfonyl, (C3-C6) cycloalkylsulfonyl,

Arylsulfonyl, (Ci-Ce)-Alkylsulfinyl, (C 3 -C 6 )-Cycloalkylsulfinyl, Arylsulfinyl, N,S- Di-(Ci-C 6 )-alkylsulfonimidoyl, S-(Ci-C 6 )-Alkylsulfonimidoyl, (Ci-C 6 )- Alkylsulfonylaminocarbonyl, (C3-C6)-Cycloalkylsulfonylaminocarbonyl, (C3-C6)- Cycloalkylaminosulfonyl, Aryl-(Ci-C6)-alkylcarbonylamino, (C3-C6)-Cycloalkyl- (Ci-C6)-alkylcarbonylamino, Heteroarylcarbonylamino, (Ci-C6)-Alkoxy-(Ci-C6)- alkylcarbonylamino, Hydroxy-(Ci-C6)-alkylcarbonylamino steht, für H, Nitro, Amino, Cyano, Halogen, (Ci-C 6 )-Alkyl, (C 3 -C 6 )-Cycloalkyl, Arylsulfonyl, (Ci-Ce) alkylsulfinyl, (C 3 -C 6) -Cycloalkylsulfinyl, arylsulfinyl, N, S-di- (Ci-C 6) -alkylsulfonimidoyl, S- (Ci-C 6) -Alkylsulfonimidoyl, (C C6) - alkylsulphonylaminocarbonyl, (C3-C6) -Cycloalkylsulfonylaminocarbonyl, (C3-C6) - Cycloalkylaminosulfonyl, aryl (Ci-C6) alkylcarbonylamino, (C3-C6) cycloalkyl (Ci-C6) alkylcarbonylamino, heteroarylcarbonylamino , (Ci-C6) alkoxy (Ci-C6) - alkylcarbonylamino, hydroxy (Ci-C6) alkylcarbonylamino, represents H, nitro, amino, cyano, halogen, (Ci-C 6) alkyl, (C 3 -C 6) -cycloalkyl,

(C 2 -C 6 )-Alkenyl, (C 2 -C 6 )-Alkinyl, Aryl, Aryl-(Ci-C 6 )-alkyl, Heteroaryl, (Ci-C 6 )- Alkoxy-(Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkyl, (C 3 -C 6 )-Halocycloalkyl, (Ci-C 6 )-Alkoxy, (Ci-C 6 )-Haloalkoxy, (Ci-C 6 )-Alkylthio, (Ci-C 6 )-Haloalkylthio, (Ci-C 6 )- Alkoxycarbonyl, Hydroxycarbonyl, Aminocarbonyl, (C1-C6)- Alkylaminocarbonyl, (Ci-C6)-Alkylamino, Bis-(Ci-C6)-alkylamino, (C3-C6)- Cycloalkylamino, (Ci-C6)-Alkylcarbonylamino, (C3-C6)- Cycloalkylcarbonylamino, Formylamino, (Ci-C6)-Haloalkylcarbonylamino, (Ci-C6)-Alkoxycarbonylamino, [(Ci-C6)-Alkyl-]aminocarbonyl-amino, (C 2 -C 6) -alkenyl, (C 2 -C 6) -alkynyl, aryl, aryl- (Ci-C 6) alkyl, heteroaryl, (Ci-C 6) - alkoxy- (Ci-C 6) alkyl, (Ci-C 6) -haloalkyl, (C 3 -C 6) halocycloalkyl, (Ci-C 6) alkoxy, (Ci-C 6) haloalkoxy, (Ci-C 6) -alkylthio, ( Ci-C 6) haloalkylthio, (Ci-C 6) - alkoxycarbonyl, hydroxycarbonyl, aminocarbonyl, (C1-C6) - alkylaminocarbonyl, (Ci-C6) alkylamino, bis (Ci-C6) alkylamino, (C 3 C6) - cycloalkylamino, (Ci-C6) alkylcarbonylamino, (C3-C6) - cycloalkylcarbonylamino, formylamino, (Ci-C6) -Haloalkylcarbonylamino, (Ci-C6) alkoxycarbonylamino, [(Ci-C6) alkyl] aminocarbonyl amino,

Sulfonylamino, (Ci-C6)-Alkylsulfonylamino, (Ci-C6)-Haloalkylsulfonylamino, (C3-C6)-Cycloalkylsulfonylamino, Amino-(Ci-C6)-alkylsulfonyl, Amino-(Ci-C6)- haloalkylsulfonyl, (Ci-C6)-Alkylsulfonyl, (C3-C6)-Cycloalkylsulfonyl, Sulfonylamino, (Ci-C6) alkylsulfonylamino, (Ci-C6) -Haloalkylsulfonylamino, (C3-C6) -Cycloalkylsulfonylamino, amino (Ci-C6) alkylsulfonyl, amino (Ci-C6) - haloalkylsulfonyl, (Ci-C6 ) alkylsulfonyl, (C3-C6) cycloalkylsulfonyl,

Arylsulfonyl, (Ci-C 6 )-Alkylsulfinyl, (C 3 -C 6 )-Cycloalkylsulfinyl, Arylsulfinyl, N,S- Di-(Ci-C 6 )-alkylsulfonimidoyl, S-(Ci-C 6 )-Alkylsulfonimidoyl, (Ci-C 6 )- Alkylsulfonylaminocarbonyl, (C3-C6)-Cycloalkylsulfonylaminocarbonyl, (C3-C6)- Cycloalkylaminosulfonyl, Amino-(Ci-C6)-alkyl, Amino-(C2-C6)-alkenyl, (C2-C6)- Alkenylamino, (C2-C6)-Alkenylimino steht, für H, Nitro, Amino, Cyano, Halogen, (Ci-C 6 )-Alkyl, (C 3 -C 6 )-Cycloalkyl, Arylsulfonyl, (Ci-C 6) alkylsulfinyl, (C 3 -C 6) -Cycloalkylsulfinyl, arylsulfinyl, N, S-di- (Ci-C 6) -alkylsulfonimidoyl, S- (Ci-C 6) -Alkylsulfonimidoyl, ( Ci-C 6) - alkylsulphonylaminocarbonyl, (C3-C6) -Cycloalkylsulfonylaminocarbonyl, (C3-C6) - Cycloalkylaminosulfonyl, amino (Ci-C6) alkyl, amino (C2-C6) -alkenyl, (C2-C6) - alkenylamino, (C2-C6) -Alkenylimino, represents H, nitro, amino, cyano, halogen, (Ci-C 6) -alkyl, (C 3 -C 6) -cycloalkyl,

(C 2 -C 6 )-Alkenyl, (C 2 -C 6 )-Alkinyl, Aryl, Aryl-(Ci-C 6 )-alkyl, Heteroaryl, (Ci-C 6 )- Alkoxy-(Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkyl, (C 3 -C 6 )-Halocycloalkyl, (Ci-C 6 )-Alkoxy, (Ci-C 6 )-Haloalkoxy, (Ci-Ce)-Alkylthio, (Ci-Ce)-Haloalkylthio, (Ci-C 6 )- Alkoxycarbonyl, Hydroxycarbonyl, Aminocarbonyl, (C1-C6)- Alkylaminocarbonyl, (Ci-C6)-Alkylamino, Bis-(Ci-C6)-alkylamino, (C3-C6)- Cycloalkylamino, (Ci-C6)-Alkylcarbonylamino, (C3-C6)- Cycloalkylcarbonylamino, Formylamino, (Ci-C6)-Haloalkylcarbonylamino, (Ci-C6)-Alkoxycarbonylamino, [(Ci-C6)-Alkyl-]-aminocarbonyl-amino, (C 2 -C 6) -alkenyl, (C 2 -C 6) -alkynyl, aryl, aryl- (Ci-C 6) alkyl, heteroaryl, (Ci-C 6) - alkoxy- (Ci-C 6) alkyl, (Ci-C 6) -haloalkyl, (C 3 -C 6) halocycloalkyl, (Ci-C 6) alkoxy, (Ci-C 6) haloalkoxy, (Ci-Ce) alkylthio, (C -ce) haloalkylthio, (Ci-C 6) - alkoxycarbonyl, hydroxycarbonyl, aminocarbonyl, (C1-C6) - alkylaminocarbonyl, (Ci-C6) alkylamino, bis (Ci-C6) alkylamino, (C3-C6) - cycloalkylamino, (Ci-C6) alkylcarbonylamino, (C3-C6) - cycloalkylcarbonylamino, formylamino, (Ci-C6) -Haloalkylcarbonylamino, (Ci-C6) alkoxycarbonylamino, [(Ci-C6) alkyl -] - aminocarbonyl amino,

Sulfonylamino, (Ci-C6)-Alkylsulfonylamino, (Ci-C6)-Haloalkylsulfonylamino, (C3-C6)-Cycloalkylsulfonylamino, Amino-(Ci-C6)-alkylsulfonyl, Amino-(Ci-C6)- haloalkylsulfonyl, (Ci-C6)-Alkylsulfonyl, (C3-C6)-Cycloalkylsulfonyl, Sulfonylamino, (Ci-C6) alkylsulfonylamino, (Ci-C6) -Haloalkylsulfonylamino, (C3-C6) -Cycloalkylsulfonylamino, amino (Ci-C6) alkylsulfonyl, amino (Ci-C6) - haloalkylsulfonyl, (Ci-C6 ) alkylsulfonyl, (C3-C6) cycloalkylsulfonyl,

Arylsulfonyl, (Ci-Ce)-Alkylsulfinyl, (C3-C 6 )-Cycloalkylsulfinyl, Arylsulfinyl, N,S- Di-(Ci-C 6 )-alkylsulfonimidoyl, S-(Ci-C 6 )-Alkylsulfonimidoyl, (Ci-C 6 )- Alkylsulfonylaminocarbonyl, (C3-C6)-Cycloalkylsulfonylaminocarbonyl, (C3-C6)- Cycloalkylaminosulfonyl, Amino-(Ci-C6)-alkyl, Amino-(C2-C6)-alkenyl, (C2-C6)- Alkenylamino, (C2-C6)-Alkenylimino steht, Arylsulfonyl, (Ci-Ce) alkylsulfinyl, (C3-C 6) -Cycloalkylsulfinyl, arylsulfinyl, N, S-di- (Ci-C 6) -alkylsulfonimidoyl, S- (Ci-C 6) -Alkylsulfonimidoyl, (Ci- C 6) - alkylsulphonylaminocarbonyl, (C3-C6) -Cycloalkylsulfonylaminocarbonyl, (C3-C6) - Cycloalkylaminosulfonyl, amino (Ci-C6) alkyl, amino (C2-C6) -alkenyl, (C2-C6) - alkenylamino, (C2-C6) -Alkenylimino stands,

R 1 und R 2 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten, teilgesättigten oder vollständig ungesättigten, gegebenenfalls durch R 1 and R 2 with the atoms to which they are attached form a fully saturated, partially saturated or fully unsaturated, optionally substituted by

Heteroatome unterbrochenen und gegebenenfalls weiter durch W Heteroatoms and optionally further interrupted by W

substituierten 5 bis 7-gliedrigen Ring bilden, und wobei sie im Falle der Verbindungen der allgemeinen Formel (I) mit den Gruppierungen Q-21 und Q- 23 einen entsprechenden Ring bilden müssen. substituted 5 to 7-membered ring, and being (I) to form with the moieties Q-21 and Q 23, a corresponding ring in the case of compounds of the general formula.

R 1 und A 3 , wenn A 3 für eine Gruppe CW steht, mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten, teilgesättigten oder vollständig R 1 and A 3, when A 3 is a group CW, with the atoms to which they are attached form a fully saturated, partially saturated or fully

ungesättigten, gegebenenfalls durch Heteroatome unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, unsaturated, optionally interrupted by hetero atoms and optionally further substituted form 5 to 7-membered ring,

X für eine direkte Bindung oder für eine Gruppierung (CHR 3 ) n steht, und wobei R 3 in der Gruppierung (CHR 3 ) n jeweils gleiche oder verschiedene X represents a direct bond or a group (CHR 3) n and wherein R 3 in the group (CHR 3) n are identical or different

Bedeutungen gemäß der nachstehenden Definition hat, n für 0, 1 steht Meanings as defined below, has n is 0, 1 is

R 3 für H, (Ci-Ce)-Alkyl, (C 2 -Ce)-Alkenyl-(Ci-Ce)-alkyl, (Ci-Ce)-Haloalkyl, (C 3 -C 6 )- Cycloalkyl, (C3-Ce)-Cycloalkyl-(Ci-Ce)-alkyl, Aryl-(Ci-Ce)-alkyl, Heteroaryl- (Ci-Ce)-alkyl, (Ci-C 6 )-Alkoxy-(Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkoxy-(Ci-C 6 )-alkyl, (Ci-Ce)-Alkylthio-(Ci-Ce)-alkyl, (Ci-C 6 )-Haloalkylthio-(Ci-C 6 )-alkyl steht, R 3 is H, (Ci-Ce) alkyl, (C2 -Ce) alkenyl (Ci-Ce) alkyl, (Ci-Ce) -haloalkyl, (C 3 -C 6) - cycloalkyl, (C3 -ce) cycloalkyl (Ci-Ce) alkyl, aryl (Ci-Ce) alkyl, heteroaryl (Ci-Ce) alkyl, (Ci-C 6) alkoxy (Ci-C 6) - alkyl, (Ci-C 6) haloalkoxy (Ci-C 6) alkyl, (Ci-Ce) alkylthio (Ci-Ce) alkyl, (Ci-C 6) -Haloalkylthio- (Ci-C 6 ) -alkyl,

R 4 für H, (Ci-Ce)-Alkyl, (C 2 -Ce)-Alkenyl-(Ci-Ce)-alkyl, (C 2 -C 6 )-Alkinyl, (Ci-C 6 )- Alkylcarbonyl, (C3-C6)-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl, (Ci-C6)-Alkoxycarbonyl, Aryl-(Ci-C6)-alkoxycarbonyl, (C3-C-6)- Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkoxycarbonyl, (Ci-Ce)- Alkylsulfonyl, (C3-C6)-Cycloalkylsulfonyl, Arylsulfonyl, (Ci-Ce)- Alkoxycarbonylcarbonyl, Aryl-(Ci-C6)-alkoxycarbonylcarbonyl, (Ci-Ce)- Alkylaminothiocarbonyl, (Ci-C6)-Alkylaminocarbonyl, Aryl-(Ci-C6)-alkyl, Hetaroaryl-(Ci-C 6 )-alkyl, Cyano-(Ci-C 6 )-alkyl, (Ci-Ce)-Haloalkyl, (C 3 -C 6 )- Cycloalkyl, (C3-C 6 )-Cycloalkyl-(Ci-C 6 )-alkyl, (Ci-C 6 )-Alkoxy-(Ci-C 6 )-alkyl, R 4 is H, (Ci-Ce) alkyl, (C2 -Ce) alkenyl (Ci-Ce) alkyl, (C 2 -C 6) alkynyl, (Ci-C 6) - alkylcarbonyl, ( C3-C6) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl, (Ci-C6) alkoxycarbonyl, aryl (Ci-C6) -alkoxycarbonyl, (C3-C6) - cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci C6) -alkoxycarbonyl, (Ci-Ce) - alkylsulfonyl, (C3-C6) cycloalkylsulfonyl, arylsulphonyl, (Ci-Ce) - alkoxycarbonylcarbonyl, aryl (Ci-C6) -alkoxycarbonylcarbonyl, (Ci-Ce) - alkylaminothiocarbonyl, ( Ci-C6) alkylaminocarbonyl, aryl (Ci-C6) alkyl, Hetaroaryl- (Ci-C 6) alkyl, cyano (Ci-C 6) alkyl, (Ci-Ce) -haloalkyl, (C 3 -C 6) - cycloalkyl, (C3-C6) cycloalkyl (Ci-C 6) alkyl, (Ci-C 6) alkoxy (Ci-C 6) alkyl,

(Ci-Ce)-Haloalkoxy-(Ci-Ce)-alkyl, (C2-C 6 )-Alkinyl-(Ci-C 6 )-alkyl, (Ci-C 6 )- Alkoxycarbonyl-(Ci-C6)-alkyl, Aminocarbonyl-(Ci-C6)-alkyl, (C1-C6)- Alkylaminocarbonyl-(Ci-C6)-alkyl, Bis-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl steht, (Ci-Ce) haloalkoxy (Ci-Ce) alkyl, (C2-C6) alkynyl (Ci-C 6) alkyl, (Ci-C 6) - alkoxycarbonyl (Ci-C6) alkyl , aminocarbonyl (Ci-C6) alkyl, (C1-C6) - alkylaminocarbonyl (Ci-C6) alkyl, bis (Ci-C6) alkylaminocarbonyl (Ci-C6) alkyl,

R 5 für Halogen, (C2-C 6 )-Alkyl, (Ci-C 6 )-Alkoxy, (Ci-C 6 )-Alkoxycarbonyloxy, R 5 is halogen, (C2-C 6) -alkyl, (Ci-C 6) alkoxy, (Ci-C 6) alkoxycarbonyloxy,

(C 2 -C 6 )-Alkenyl, (C 2 -C 6 )-Haloalkenyl, (C 2 -C 6 )-Alkenyl-(Ci-C 6 )-alkyl, (C 2 -C 6 )- Alkinyl, (C 2 -C 6 )-Alkinyl-(Ci-C 6 )-alkyl, Aryl-(Ci-C 6 )-alkyl, Bisaryl-(Ci-C 6 )-alkyl, Aryl-(Ci-C 6 )-alkoxyaryl-(Ci-C 6 )-alkyl, Aryloxyaryl-(Ci-C 6 )-alkyl, (Ci-C 6 )- Alkoxyaryl-(Ci-C6)-alkyl, Heteroaryl-(Ci-C6)-alkyl, Heterocyclyl-(Ci-C6)-alkyl, N-(Ci-Ce)-Alkylheterocyclyl-(Ci-Ce)-alkyl, N-[(Ci-C 6 )- Alkoxycarbonyl]heterocyclyl-(Ci-C6)-alkyl, N-(Aryl-(Ci-C6)- alkoxycarbonyl)heterocyclyl-(Ci-C6)-alkyl, N-(Arylcarbonyl)heterocyclyl- (Ci-Ce)-alkyl, N-[(Ci-C 6 )-Alkylcarbonyl]heterocyclyl-(Ci-C 6 )-alkyl, N-[(C 3 -C 6 )- Cycloalkylcarbonyl]heterocyclyl-(Ci-C6)-alkyl, Cyano-(Ci-C6)-alkyl, (Ci-Ce)- Haloalkyl, (C 3 -C 6 )-Cycloalkyl, (C 3 -C 6 )-Halocycloalkyl, (C 4 -C 6 )-Cycloalkenyl, (C3-Ce)-Cycloalkyl-(Ci-Ce)-alkyl, (C3-Ce)-Cycloalkenyl-(Ci-Ce)-alkyl, Hydroxy- (Ci-Ce)-alkyl, (Ci-C 6 )-Alkoxy-(Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkoxy-(Ci-C 6 )-alkyl, Aryloxy-(Ci-Ce)-alkyl, Aryl-(Ci-Ce)-alkoxy-(Ci-Ce)-alkyl, Heteroaryl-(Ci-C 6 )- alkoxy-(Ci-Ce)-alkyl, (C3-Ce)-Cycloalkoxy-(Ci-Ce)-alkyl, (C 3 -C 6 )-Cycloalkyl- (Ci-Ce)-alkoxy-(Ci-Ce)-alkyl, (Ci-Ce)-Alkylcarbonyloxy-(Ci-Ce)-alkyl, (C 2 -C 6) -alkenyl, (C 2 -C 6) haloalkenyl, (C 2 -C 6) alkenyl (Ci-C 6) alkyl, (C 2 -C 6) - alkynyl, ( C 2 -C 6) alkynyl (Ci-C 6) alkyl, aryl (Ci-C 6) alkyl, bisaryl (Ci-C 6) alkyl, aryl (Ci-C 6) alkoxyaryl - (Ci-C 6) alkyl, Aryloxyaryl- (Ci-C 6) alkyl, (Ci-C 6) - alkoxyaryl (Ci-C6) alkyl, heteroaryl (Ci-C6) alkyl, heterocyclyl (Ci-C6) alkyl, N- (Ci-Ce) -Alkylheterocyclyl- (Ci-Ce) alkyl, N - [(Ci-C 6) - alkoxycarbonyl] heterocyclyl (Ci-C6) alkyl, N- (aryl (Ci-C6) - alkoxycarbonyl) heterocyclyl (Ci-C6) alkyl, N- (arylcarbonyl) heterocyclyl (Ci-Ce) alkyl, N - [(Ci-C6) alkyl-carbonyl] heterocyclyl- (Ci-C 6) -alkyl, N - [(C 3 -C 6) - cycloalkylcarbonyl] heterocyclyl (Ci-C6) -alkyl, cyano- (Ci-C6) alkyl, (Ci-Ce) - haloalkyl, (C 3 -C 6) -cycloalkyl, (C 3 -C 6) halocycloalkyl, (C 4 -C 6) -cycloalkenyl, (C3-Ce) cycloalkyl (Ci-Ce) alkyl, (C3-Ce ) cycloalkenyl (Ci-Ce) alkyl, hydroxy (Ci-Ce) alkyl, (Ci-C 6) alkoxy (Ci-C 6) alkyl, (Ci-C 6) haloalkoxy ( Ci-C 6) alkyl, aryloxy (Ci-Ce) alkyl, aryl (Ci-Ce) alkoxy (Ci-Ce) alkyl, heteroaryl (Ci-C6) - alkoxy- (Ci Ce) alkyl, (C3-Ce) cycloalkoxy (Ci-Ce) alkyl, (C 3 -C 6) cycloalkyl (Ci-Ce) alkoxy (Ci-Ce) alkyl, (Ci- Ce) alkylcarbonyloxy (Ci-Ce) alkyl,

Arylcarbonyloxy-(Ci-C6)-alkyl, Heteroarylcarbonyloxy-(Ci-C6)-alkyl, (C3-C-6)- Cycloalkylcarbonyloxy-(Ci-C6)-alkyl, Arylsulfonyloxy-(Ci-C6)-alkyl, (Ci-Ce)- Alkylsulfonyloxy-(Ci-Ce)-alkyl, Hydrothio-(Ci-Ce)-alkyl, (Ci-Ce)-Alkylthio- (Ci-Ce)-alkyl, (Ci-C 6 )-Haloalkylthio-(Ci-C 6 )-alkyl, Aryl-(Ci-C 6 )-alkylthio- (Ci-Ce)-alkyl, (C3-Ce)-Cycloalkylthio-(Ci-Ce)-alkyl, Arylthio-(Ci-Ce)-alkyl, Arylcarbonyloxy (Ci-C6) alkyl, Heteroarylcarbonyloxy- (Ci-C6) alkyl, (C3-C6) - Cycloalkylcarbonyloxy- (Ci-C6) alkyl, arylsulfonyloxy (Ci-C6) alkyl, (Ci -ce) - alkylsulfonyloxy (Ci-Ce) alkyl, Hydrothio- (Ci-Ce) alkyl, (Ci-Ce) alkylthio (Ci-Ce) alkyl, (Ci-C 6) -Haloalkylthio- ( Ci-C 6) alkyl, aryl (Ci-C 6) alkylthio (Ci-Ce) alkyl, (C3-Ce) cycloalkylthio (Ci-Ce) alkyl, arylthio (Ci-Ce) alkyl,

(Ci-Ce)-Alkylsulfinyl-(Ci-Ce)-alkyl, (Ci-C 6 )-Alkylsulfonyl-(Ci-C 8 )-alkyl, (Ci-C 6 )- Haloalkylsulfinyl-(Ci-Ce)-alkyl, (Ci-C 6 )-Haloalkylsulfonyl-(Ci-C 6 )-alkyl, Aryl- (Ci-Ce)-alkylsulfinyl-(Ci-Ce)-alkyl, Aryl-(Ci-Ce)-alkylsulfonyl-(Ci-Ce)-alkyl, (C3-Ce)-Cycloalkylsulfinyl-(Ci-Ce)-alkyl, (C3-C 6 )-Cycloalkylsulfonyl-(Ci-C 6 )- alkyl, Aryl, Heteroaryl, Heterocyclyl, N-[(Ci-C 6 )-Alkyl]heterocyclyl, N-[(Ci-C 6 )- Alkoxycarbonyl]heterocyclyl, N-[Aryl-(Ci-C6)-alkoxycarbonyl]heterocyclyl, N- (Arylcarbonyl)heterocyclyl, N-[(Ci-C6)-Alkylcarbonyl]heterocyclyl, N-[(Ci-Ce)- Cycloalkylcarbonyl]heterocyclyl, Hydroxycarbonyl, (Ci-CeJ-Alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkoxycarbonyl, Aryl- (Ci-CeJ-alkoxycarbonyl, Heteroaryl-(Ci-C6)-alkoxycarbonyl, (Ci-Ce)- Alkylaminocarbonyl, Aminocarbonyl, Bis-(Ci-C6)-alkylaminocarbonyl, (C3-C6)- Cycloalkylaminocarbonyl, Aryl-(Ci-C6)-alkylaminocarbonyl, (Ci-Ce) alkylsulfinyl (Ci-Ce) alkyl, (Ci-C 6) alkylsulfonyl (Ci-C 8) alkyl, (Ci-C 6) - Haloalkylsulfinyl- (Ci-Ce) alkyl , (Ci-C 6) -Haloalkylsulfonyl- (Ci-C 6) alkyl, aryl (Ci-Ce) alkylsulfinyl (Ci-Ce) alkyl, aryl (Ci-Ce) alkylsulfonyl (CI- Ce) alkyl, (C3-Ce) -Cycloalkylsulfinyl- (Ci-Ce) alkyl, (C3-C 6) -Cycloalkylsulfonyl- (Ci-C 6) - alkyl, aryl, heteroaryl, heterocyclyl, N - [(C -C 6) alkyl] heterocyclyl, N - [(Ci-C 6) - alkoxycarbonyl] heterocyclyl, N- [aryl (Ci-C6) -alkoxycarbonyl] heterocyclyl, N- (arylcarbonyl) heterocyclyl, N - [(C C6) alkyl-carbonyl] heterocyclyl, N - [(Ci-Ce) - cycloalkylcarbonyl] heterocyclyl, hydroxycarbonyl, (C CeJ -alkoxycarbonyl, (C3-C6) cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C6 ) alkoxycarbonyl, aryl (Ci-CeJ-alkoxycarbonyl, heteroaryl (Ci-C6) -alkoxycarbonyl, (Ci-Ce) - alkylaminocarbonyl, aminocarbonyl, bis (Ci-C6) alkylaminocarbonyl, (C3-C6) - cycloalkylaminocarbonyl , aryl (Ci-C6) alkylaminocarbonyl,

Heteroarylaminocarbonyl, Cyano-(Ci-C6)-alkylaminocarbonyl, (Ci-Ce)- Haloalkylaminocarbonyl, (C2-C6)-Alkinyl-(Ci-C6)-alkylaminocarbonyl, Heteroarylaminocarbonyl, cyano (Ci-C6) alkylaminocarbonyl, (Ci-Ce) - Haloalkylaminocarbonyl, (C2-C6) alkynyl (Ci-C6) alkylaminocarbonyl,

Hydroxycarbonyl-(Ci-C-6)-alkyl, (Ci-C6)-Alkoxycarbonyl-(Ci-C6)-alkyl, (C3-C6)- Cycloalkoxycarbonyl-(Ci-C6)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkoxycarbonyl- (Ci-Ce)-alkyl, Aryl-(Ci-C 6 )-alkoxycarbonyl-(Ci-C 6 )-alkyl, Heteroaryl-(Ci-C 6 )- alkoxycarbonyl-(Ci-C6)-alkyl, (Ci-C6)-Alkylaminocarbonyl-(Ci-C6)-alkyl, Aminocarbonyl-(Ci-C-6)-alkyl, Bis-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, (C3-C6)-Cycloalkylaminocarbonyl-(Ci-C6)-alkyl, Aryl-(Ci-C6)- alkylaminocarbonyl-(Ci-C6)-alkyl, Heteroarylaminocarbonyl-(Ci-C6)-alkyl, Cyano-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, (Ci-Ce)- Haloalkylaminocarbonyl-(Ci-C 6 )-alkyl, (C2-C 8 )-Alkinyl-(Ci-C 8 )- alkylaminocarbonyl-(Ci-C8)-alkyl, Amino-(Ci-C6)-alkyl, (Ci-C6)-Alkylamino- (Ci-C 6 )-alkyl, (C2-C 6 )-Alkenylamino-(Ci-C 6 )-alkyl, Arylamino-(Ci-C 6 )-alkyl, Bis- (Ci-C6)-alkylamino-(Ci-C6)-alkyl, Bis-(C3-C6)-cycloalkylamino-(Ci-C6)-alkyl, Aryl-(Ci-C 6 )-alkylamino-(Ci-C 6 )-alkyl, Tns-Aryl-(Ci-C 6 )-alkylamino-(Ci-C 6 )- alkyl, (C3-C6)-Cycloalkylamino-(Ci-C 6 )-alkyl, (C3-C 6 )-Cycloalkyl-(Ci-C 6 )- alkylamino-(Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkylamino-(Ci-C 6 )-alkyl, (Ci-C 6 )- Alkylcarbonylamino-(Ci-C6)-alkyl, (Ci-C6)-Cycloalkylcarbonylamino-(Ci-C6)- alkyl, Arylcarbonylamino-(Ci-C6)-alkyl, Heteroarylcarbonylamino-(Ci-C6)-alkyl, (Ci-C6)-Alkoxycarbonylamino-(Ci-C6)-alkyl, (C2-C6)-Alkenyloxycarbonylamino- (Ci-C 6 )-alkyl, Aryl-(Ci-C 6 )-alkoxycarbonylamino-(Ci-C 6 )-alkyl, Aryl-(Ci-C 6 )- alkoxycarbonyl[N-(Ci-C6)-alkyl]amino-(Ci-C6)-alkyl, Heteroaryl-(Ci-C6)- alkoxycarbonylamino-(Ci-C6)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C6)- alkoxycarbonylamino-(Ci-C6)-alkyl, (C3-C6)-Cycloalkoxycarbonylamino- (Ci-C6)-alkyl, Aminocarbonylamino-(Ci-C6)-alkyl, Arylsulfonylamino-(Ci-C6)- alkyl, Heteroarylsulfonylamino-(Ci-C6)-alkyl, (Ci-C6)-Alkylsulfonylamino- (Ci-C6)-alkyl, (C3-C6)-Cycloalkylsulfonylamino-(Ci-C6)-alkyl, Hydroxycarbonyl (C-6) alkyl, (Ci-C6) alkoxycarbonyl (C C6) alkyl, (C3-C6) - Cycloalkoxycarbonyl- (Ci-C6) alkyl, (C3-C6) - cycloalkyl- (Ci-C6) alkoxycarbonyl (Ci-Ce) alkyl, aryl (Ci-C 6) alkoxycarbonyl (Ci-C 6) alkyl, heteroaryl (Ci-C6) - alkoxycarbonyl ( Ci-C6) alkyl, (Ci-C6) alkylaminocarbonyl (Ci-C6) alkyl, aminocarbonyl (Ci-C-6) alkyl, bis (Ci-C6) alkylaminocarbonyl (Ci-C6) alkyl, (C3-C6) -Cycloalkylaminocarbonyl- (Ci-C6) alkyl, aryl (Ci-C6) - alkylaminocarbonyl (Ci-C6) alkyl, Heteroarylaminocarbonyl- (Ci-C6) alkyl, cyano ( Ci-C6) alkylaminocarbonyl (Ci-C6) alkyl, (Ci-Ce) - Haloalkylaminocarbonyl- (Ci-C 6) alkyl, (C2-C8) alkynyl (Ci-C 8) - alkylaminocarbonyl (Ci-C8) alkyl, amino (Ci-C6) alkyl, (Ci-C6) alkylamino (Ci-C 6) alkyl, (C2-C 6) -Alkenylamino- (Ci-C 6) alkyl, arylamino (Ci-C 6) alkyl, bis (Ci-C6) alkylamino (Ci-C6) alkyl, bis (C3-C6) cycloalkylamino (Ci-C6) alkyl, aryl (Ci-C 6) alkylamino (Ci-C 6) alkyl, Tns-aryl- (Ci-C 6) alkylamino (Ci-C 6) - alkyl, (C3-C6) cycloalkylamino (Ci-C 6) alkyl, (C3-C6) cycloalkyl (Ci-C 6) - alkylamino- (Ci-C 6) alkyl, (Ci-C 6) -Haloalkylamino- (Ci-C 6 ) alkyl, (Ci-C 6) - alkylcarbonylamino (Ci-C6) alkyl, (Ci-C6) -Cycloalkylcarbonylamino- (Ci-C6) - alkyl, arylcarbonylamino (Ci-C6) alkyl, Heteroarylcarbonylamino- ( Ci-C6) alkyl, (Ci-C6) alkoxycarbonylamino (Ci-C6) alkyl, (C2-C6) -Alkenyloxycarbonylamino- (Ci-C6) alkyl, aryl (Ci-C6) alkoxycarbonylamino - (Ci-C 6) alkyl, aryl (Ci-C 6) - alkoxycarbonyl [N- (Ci-C6) alkyl] amino- (Ci-C6) alkyl, heteroaryl (Ci-C6) - alkoxycarbonylamino - (Ci-C6) alkyl, (C3-C6) cycloalkyl (Ci-C6) - alkoxycarbonylamino (Ci-C6) alkyl, (C3-C6) -Cycloalkoxycarbonylamino- (Ci-C6) alkyl, aminocarbonylamino - (Ci-C6) alkyl, arylsulfonylamino (Ci-C6) - alkyl, Heteroarylsulfonylamino- (Ci-C6) alkyl, (Ci-C6) alkylsulfonylamino (Ci-C6) alkyl, (C3-C6) -Cycloalkylsulfonylamino- (Ci-C6) alkyl,

Aminoiminoamino-(Ci-C6)-alkyl, Arylsulfonylaminoiminoamino-(Ci-C6)-alkyl, (Ci-C6)-Alkylaminoiminoamino-(Ci-C6)-alkyl steht, für Wasserstoff, Halogen, (Ci-C 6 )-Alkyl, (Ci-C 6 )-Alkoxy, (Ci-C 6 )- Aminoiminoamino- (Ci-C6) alkyl, Arylsulfonylaminoiminoamino- (Ci-C6) alkyl, (Ci-C6) -Alkylaminoiminoamino- (Ci-C6) alkyl, represents hydrogen, halogen, (Ci-C 6) alkyl , (Ci-C 6) alkoxy, (Ci-C 6) -

Alkoxycarbonyloxy, (C2-C6)-Alkenyl, (C2-C6)-Haloalkenyl, (C2-C6)-Alkenyl- (Ci-C 6 )-alkyl, (C 2 -C 6 )-Alkinyl, (C2-C 6 )-Alkinyl-(Ci-C 6 )-alkyl, Aryl-(Ci-C 6 )-alkyl, Bisaryl-(Ci-C 6 )-alkyl, Aryl-(Ci-C 6 )-alkoxyaryl-(Ci-C 6 )-alkyl, Aryloxyaryl-(Ci-C 6 )- alkyl, (Ci-C6)-Alkoxyaryl-(Ci-C6)-alkyl, Heteroaryl-(Ci-C6)-alkyl, Heterocyclyl- (Ci-C 6 )-alkyl, N-(Ci-C 6 )-Alkylheterocyclyl-(Ci-C 6 )-alkyl, N-[(Ci-C 6 )- Alkoxycarbonyl]heterocyclyl-(Ci-C6)-alkyl, N-(Aryl-(Ci-Ce)- alkoxycarbonyl)heterocyclyl-(Ci-C6)-alkyl, N-(Arylcarbonyl)heterocyclyl- (Ci-C 6 )-alkyl, N-[(Ci-C 6 )-Alkylcarbonyl]heterocyclyl-(Ci-C 6 )-alkyl, N-[(C 3 -C 6 )- Cycloalkylcarbonyl]heterocyclyl-(Ci-C6)-alkyl, Cyano-(Ci-C6)-alkyl, (C1-C6)- Haloalkyl, (C 3 -C 6 )-Cycloalkyl, (C 3 -C 6 )-Halocycloalkyl, (C 4 -C 6 )-Cycloalkenyl, (C3-C 6 )-Cycloalkyl-(Ci-C 6 )-alkyl, (C3-C 6 )-Cycloalkenyl-(Ci-C 6 )-alkyl, Hydroxy- (Ci-Ce)-alkyl, (Ci-C 6 )-Alkoxy-(Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkoxy-(Ci-C 6 )-alkyl, Aryloxy-(Ci-Ce)-alkyl, Aryl-(Ci-C 6 )-alkoxy-(Ci-C 6 )-alkyl, Heteroaryl-(Ci-C 6 )- alkoxy-(Ci-C 6 )-alkyl, (C3-Ce)-Cycloalkoxy-(Ci-Ce)-alkyl, (C 3 -C 6 )-Cycloalkyl- (Ci-Ce)-alkoxy-(Ci-Ce)-alkyl, (Ci-Ce)-Alkylcarbonyloxy-(Ci-Ce)-alkyl, Alkoxycarbonyloxy, (C2-C6) -alkenyl, (C2-C6) haloalkenyl, (C2-C6) -alkenyl (Ci-C 6) alkyl, (C2-C6) -alkynyl, (C2-C6 ) alkynyl (Ci-C 6) alkyl, aryl (Ci-C 6) alkyl, bisaryl (Ci-C 6) alkyl, aryl (Ci-C 6) -alkoxyaryl- (Ci-C 6) alkyl, Aryloxyaryl- (Ci-C 6) - alkyl, (Ci-C6) -Alkoxyaryl- (Ci-C6) alkyl, heteroaryl (Ci-C6) alkyl, heterocyclyl (Ci-C 6) alkyl, N- (Ci-C 6) -Alkylheterocyclyl- (Ci-C 6) -alkyl, N - [(Ci-C 6) - alkoxycarbonyl] heterocyclyl (Ci-C6) alkyl, N- (aryl (Ci-Ce) - alkoxycarbonyl) heterocyclyl (Ci-C6) alkyl, N- (arylcarbonyl) heterocyclyl- (Ci-C 6) -alkyl, N - [(Ci-C 6) alkylcarbonyl] heterocyclyl (Ci C6) alkyl, N - [(C3-C6) - cycloalkylcarbonyl] heterocyclyl (Ci-C6) alkyl, cyano (Ci-C6) alkyl, (C1-C6) - haloalkyl, (C 3 -C 6) -cycloalkyl, (C 3 -C 6) halocycloalkyl, (C 4 -C 6) -cycloalkenyl, (C3-C6) cycloalkyl (Ci-C 6) alkyl, (C3-C 6) cycloalkenyl (Ci-C 6) alkyl, hydroxy (Ci-Ce) alkyl, (Ci-C 6) alkoxy (Ci-C 6) alkyl, (Ci-C 6) -haloalkoxy - (Ci-C 6) alkyl, aryloxy (Ci-Ce) alkyl, aryl (Ci-C 6) alkoxy (Ci-C 6) alkyl, heteroaryl (Ci-C 6) - alkoxy - (Ci-C 6) alkyl, (C3-Ce) cycloalkoxy (Ci-Ce) alkyl, (C 3 -C 6) cycloalkyl (Ci-Ce) alkoxy (Ci-Ce) - alkyl, (Ci-Ce) alkylcarbonyloxy (Ci-Ce) alkyl,

Arylcarbonyloxy-(Ci-C6)-alkyl, Heteroarylcarbonyloxy-(Ci-C6)-alkyl, (C3-C6)- Cycloalkylcarbonyloxy-(Ci-C8)-alkyl, Arylsulfonyloxy-(Ci-C6)-alkyl, (Ci-Ce)- Alkylsulfonylox -(Ci-Ce)-alkyl, Hydrothio-(Ci-Ce)-alkyl, (Ci-Ce)-Alkylthio- (Ci-Ce)-alkyl, (Ci-C 6 )-Haloalkylthio-(Ci-C 6 )-alkyl, Aryl-(Ci-C 6 )-alkylthio- (Ci-Ce)-alkyl, (C3-Ce)-Cycloalkylthio-(Ci-Ce)-alkyl, Arylthio-(Ci-Ce)-alkyl, Arylcarbonyloxy (Ci-C6) alkyl, Heteroarylcarbonyloxy- (Ci-C6) alkyl, (C3-C6) - Cycloalkylcarbonyloxy- (Ci-C8) alkyl, arylsulfonyloxy (Ci-C6) alkyl, (Ci-Ce ) - Alkylsulfonylox - (Ci-Ce) alkyl, Hydrothio- (Ci-Ce) alkyl, (Ci-Ce) alkylthio (Ci-Ce) alkyl, (Ci-C 6) -Haloalkylthio- (Ci- C 6) alkyl, aryl (Ci-C 6) alkylthio (Ci-Ce) alkyl, (C3-Ce) cycloalkylthio (Ci-Ce) alkyl, arylthio (Ci-Ce) alkyl .

(Ci-Ce)-Alkylsulfinyl-(Ci-Ce)-alkyl, (Ci-C 6 )-Alkylsulfonyl-(Ci-C 6 )-alkyl, (Ci-C 6 )- Haloalkylsulfinyl-(Ci-Ce)-alkyl, (Ci-C 6 )-Haloalkylsulfonyl-(Ci-C 6 )-alkyl, Aryl- (Ci-Ce)-alkylsulfinyl-(Ci-Ce)-alkyl, Aryl-(Ci-Ce)-alkylsulfonyl-(Ci-Ce)-alkyl, (C3-Ce)-Cycloalkylsulfinyl-(Ci-Ce)-alkyl, (C3-C 6 )-Cycloalkylsulfonyl-(Ci-C 6 )- alkyl, Aryl, Heteroaryl, Heterocyclyl, N-[(Ci-C 6 )-Alkyl]heterocyclyl, N-[(Ci-C 6 )- Alkoxycarbonyl]heterocyclyl, N-[Aryl-(Ci-C6)-alkoxycarbonyl]heterocyclyl, N- (Arylcarbonyl)heterocyclyl, N-[(Ci-C6)-Alkylcarbonyl]heterocyclyl, N-[(Ci-Ce)- Cycloalkylcarbonyl]heterocyclyl, Hydroxycarbonyl, (Ci-CeJ-Alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkoxycarbonyl, Aryl- (Ci-CeJ-alkoxycarbonyl, Heteroaryl-(Ci-C6)-alkoxycarbonyl, (Ci-Ce)- Alkylaminocarbonyl, Aminocarbonyl, Bis-(Ci-C6)-alkylaminocarbonyl, (C3-C6)- Cycloalkylaminocarbonyl, Aryl-(Ci-C6)-alkylaminocarbonyl, (Ci-Ce) alkylsulfinyl (Ci-Ce) alkyl, (Ci-C 6) alkylsulfonyl (Ci-C 6) alkyl, (Ci-C 6) - Haloalkylsulfinyl- (Ci-Ce) alkyl , (Ci-C 6) -Haloalkylsulfonyl- (Ci-C 6) alkyl, aryl (Ci-Ce) alkylsulfinyl (Ci-Ce) alkyl, aryl (Ci-Ce) alkylsulfonyl (CI- Ce) alkyl, (C3-Ce) -Cycloalkylsulfinyl- (Ci-Ce) alkyl, (C3-C 6) -Cycloalkylsulfonyl- (Ci-C 6) - alkyl, aryl, heteroaryl, heterocyclyl, N - [(C -C 6) alkyl] heterocyclyl, N - [(Ci-C 6) - alkoxycarbonyl] heterocyclyl, N- [aryl (Ci-C6) -alkoxycarbonyl] heterocyclyl, N- (arylcarbonyl) heterocyclyl, N - [(C C6) alkyl-carbonyl] heterocyclyl, N - [(Ci-Ce) - cycloalkylcarbonyl] heterocyclyl, hydroxycarbonyl, (C CeJ -alkoxycarbonyl, (C3-C6) cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C6 ) alkoxycarbonyl, aryl (Ci-CeJ-alkoxycarbonyl, heteroaryl (Ci-C6) -alkoxycarbonyl, (Ci-Ce) - alkylaminocarbonyl, aminocarbonyl, bis (Ci-C6) alkylaminocarbonyl, (C3-C6) - cycloalkylaminocarbonyl , aryl (Ci-C6) alkylaminocarbonyl,

Heteroarylaminocarbonyl, Cyano-(Ci-C6)-alkylaminocarbonyl, (Ci-Ce)- Haloalkylaminocarbonyl, (C2-C6)-Alkinyl-(Ci-C6)-alkylaminocarbonyl, Heteroarylaminocarbonyl, cyano (Ci-C6) alkylaminocarbonyl, (Ci-Ce) - Haloalkylaminocarbonyl, (C2-C6) alkynyl (Ci-C6) alkylaminocarbonyl,

Hydroxycarbonyl-(Ci-C6)-alkyl, (Ci-C6)-Alkoxycarbonyl-(Ci-C6)-alkyl, (C3-C6)- Cycloalkoxycarbonyl-(Ci-C-6)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkoxycarbonyl- (Ci-Ce)-alkyl, Aryl-(Ci-C 6 )-alkoxycarbonyl-(Ci-C 6 )-alkyl, Heteroaryl-(Ci-C 6 )- alkoxycarbonyl-(Ci-C6)-alkyl, (Ci-C6)-Alkylaminocarbonyl-(Ci-C6)-alkyl, Aminocarbonyl-(Ci-C6)-alkyl, Bis-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, (C3-C6)-Cycloalkylaminocarbonyl-(Ci-C6)-alkyl, Aryl-(Ci-C-6)- alkylaminocarbonyl-(Ci-C6)-alkyl, Heteroarylaminocarbonyl-(Ci-C6)-alkyl, Cyano-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, (Ci-Ce)- Haloalkylaminocarbonyl-(Ci-C6)-alkyl, (C2-C6)-Alkinyl-(Ci-C6)- alkylaminocarbonyl-(Ci-C6)-alkyl, Amino-(Ci-C6)-alkyl, (Ci-C6)-Alkylamino- (Ci-Ce)-alkyl, (C2-Ce)-Alkenylamino-(Ci-Ce)-alkyl, Arylamino-(Ci-C 6 )-alkyl, Bis- (Ci-C6)-alkylamino-(Ci-C6)-alkyl, Bis-(C3-C6)-cycloalkylamino-(Ci-C6)-alkyl, Aryl-(Ci-Ce)-alkylamino-(Ci-Ce)-alkyl, Tns-Aryl-(Ci-C 6 )-alkylamino-(Ci-C 6 )- alkyl, (C3-Ce)-Cycloalkylamino-(Ci-Ce)-alkyl, (C3-Ce)-Cycloalkyl-(Ci-Ce)- alkylamino-(Ci-Ce)-alkyl, (Ci-Ce)-Haloalkylamino-(Ci-Ce)-alkyl, (Ci-C 6 )- Alkylcarbonylamino-(Ci-C6)-alkyl, (Ci-C6)-Cycloalkylcarbonylamino-(Ci-C6)- alkyl, Arylcarbonylamino-(Ci-C6)-alkyl, Heteroarylcarbonylamino-(Ci-C6)-alkyl, (Ci-C6)-Alkoxycarbonylamino-(Ci-C6)-alkyl, (C2-C6)-Alkenyloxycarbonylamino- (Ci-Ce)-alkyl, Aryl-(Ci-Ce)-alkoxycarbonylamino-(Ci-Ce)-alkyl, Aryl-(Ci-Ce)- alkoxycarbonyl[N-(Ci-C6)-alkyl]amino-(Ci-C6)-alkyl, Heteroaryl-(Ci-C6)- alkoxycarbonylamino-(Ci-C6)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C-6)- alkoxycarbonylamino-(Ci-C-6)-alkyl, (C3-C6)-Cycloalkoxycarbonylamino- (Ci-CeJ-alkyl, Aminocarbonylamino-(Ci-C6)-alkyl, Arylsulfonylamino-(Ci-C6)- alkyl, Heteroarylsulfonylamino-(Ci-C6)-alkyl, (Ci-C6)-Alkylsulfonylamino- (Ci-CeJ-alkyl, (C3-C6)-Cycloalkylsulfonylamino-(Ci-C6)-alkyl, Hydroxycarbonyl (Ci-C6) alkyl, (Ci-C6) alkoxycarbonyl (C C6) alkyl, (C3-C6) - Cycloalkoxycarbonyl- (C-6) alkyl, (C3-C6) - cycloalkyl- (Ci-C6) alkoxycarbonyl (Ci-Ce) alkyl, aryl (Ci-C 6) alkoxycarbonyl (Ci-C 6) alkyl, heteroaryl (Ci-C6) - alkoxycarbonyl ( Ci-C6) alkyl, (Ci-C6) alkylaminocarbonyl (Ci-C6) alkyl, aminocarbonyl (Ci-C6) alkyl, bis (Ci-C6) alkylaminocarbonyl (Ci-C6) alkyl , (C3-C6) -Cycloalkylaminocarbonyl- (Ci-C6) alkyl, aryl (C-6) - alkylaminocarbonyl (Ci-C6) alkyl, Heteroarylaminocarbonyl- (Ci-C6) alkyl, cyano ( Ci-C6) alkylaminocarbonyl (Ci-C6) alkyl, (Ci-Ce) - Haloalkylaminocarbonyl- (Ci-C6) alkyl, (C2-C6) alkynyl (Ci-C6) - alkylaminocarbonyl (Ci C6) alkyl, amino (Ci-C6) alkyl, (Ci-C6) alkylamino (Ci-Ce) alkyl, (C2-Ce) -Alkenylamino- (Ci-Ce) alkyl, arylamino ( Ci-C 6) alkyl, bis (Ci-C6) alkylamino (Ci-C6) alkyl, bis (C3-C6) cycloalkylamino (Ci-C6) alkyl, aryl (Ci-Ce ) alkylamino (Ci-Ce) alkyl, Tns-aryl- (Ci-C 6) alkylamino (Ci-C 6) - alkyl, (C3-Ce) cycloalkylamino (Ci-Ce) alkyl (C3-Ce) cycloalkyl (Ci-Ce) - alkylamino (Ci-Ce) alkyl, (Ci-Ce) -Haloalkylamino- (Ci-Ce) alkyl, (Ci-C 6) - alkylcarbonylamino ( Ci-C6) alkyl, (Ci-C6) -Cycloalkylcarbonylamino- (Ci-C6) - alkyl, arylcarbonylamino (Ci-C6) alkyl, Heteroarylcarbonylamino- (Ci-C6) alkyl, (Ci-C6) alkoxycarbonylamino - (Ci-C6) alkyl, (C2-C6) -Alkenyloxycarbonylamino- (Ci-Ce) alkyl, aryl (Ci-Ce) alkoxycarbonylamino (Ci-Ce) alkyl, aryl (Ci-Ce) - alkoxycarbonyl [N- (Ci-C6) alkyl] amino (Ci-C6) alkyl, heteroaryl (Ci-C6) - alkoxycarbonylamino (Ci-C6) alkyl, (C3-C6) cycloalkyl ( Ci-C-6) - alkoxycarbonylamino (Ci-C-6) alkyl, (C3-C6) -Cycloalkoxycarbonylamino- (Ci-CeJ-alkyl, aminocarbonylamino (Ci-C6) alkyl, arylsulfonylamino (Ci-C6 ) - alkyl, Heteroarylsulfonylamino- (Ci-C6) alkyl, (Ci-C6) alkylsulfonylamino (Ci-CeJ-alkyl, (C3-C6) -Cycloalkylsulfonylamino- (Ci-C6) alkyl,

Aminoiminoamino-(Ci-C6)-alkyl, Arylsulfonylaminoiminoamino-(Ci-C6)-alkyl, (Ci-C6)-Alkylaminoiminoamino-(Ci-C6)-alkyl steht, Aminoiminoamino- (Ci-C6) alkyl, Arylsulfonylaminoiminoamino- (Ci-C6) alkyl, (Ci-C6) -Alkylaminoiminoamino- (Ci-C6) alkyl,

R 6 und R 8 unabhängig voneinander für H, (Ci-Ce)-Alkyl, (C2-C 6 )-Alkenyl-(Ci-C 6 )- alkyl, (C2-Ce)-Alkinyl-(Ci-Ce)-alkyl, Aryl-(Ci-C 6 )-alkyl, (C 3 -C 6 )-Cycloalkyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkyl, Heterocyclyl, Heterocyclyl-(Ci-C6)-alkyl, Amino-(Ci-C 6 )-alkyl, (Ci-Ce)-Alkoxy-(Ci-Ce)-alkyl, (Ci-C 6 )-Alkylthio-(Ci-C 6 )- alkyl, (Ci-Ce)-Haloalkyl, (Ci-Ce)-Alkylamino-(Ci-Ce)-alkyl, Bis-(Ci-Ce)- alkylamino-(Ci-C6)-alkyl, (Ci-C6)-Alkylcarbonylamino-(Ci-C6)-alkyl, (C3-C6)- Cycloalkylcarbonylamino-(Ci-C6)-alkyl, Arylcarbonylamino-(Ci-C6)-alkyl, R 6 and R 8 independently represent H, (Ci-Ce) alkyl, (C2-C6) alkenyl (Ci-C 6) - alkyl, (C2-Ce) alkynyl (Ci-Ce) - alkyl, aryl (Ci-C 6) alkyl, (C 3 -C 6) -cycloalkyl, (C3-C6) cycloalkyl (Ci-C6) alkyl, heterocyclyl, heterocyclyl (Ci-C6) alkyl , amino (Ci-C 6) alkyl, (Ci-Ce) alkoxy- (Ci-Ce) alkyl, (Ci-C 6) alkylthio (Ci-C 6) - alkyl, (Ci-Ce ) -haloalkyl, (Ci-Ce) -alkylamino (Ci-Ce) alkyl, bis (Ci-Ce) - alkylamino (Ci-C6) alkyl, (Ci-C6) -alkylcarbonylamino- (Ci-C6 ) alkyl, (C3-C6) - Cycloalkylcarbonylamino- (Ci-C6) alkyl, arylcarbonylamino (Ci-C6) alkyl,

(Ci-C6)-Alkoxycarbonylamino-(Ci-C6)-alkyl, Aryl-(Ci-C6)-alkoxycarbonylamino- (Ci-CeJ-alkyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkoxycarbonylamino-(Ci-C6)-alkyl, Aminocarbonylamino-(Ci-C-6)-alkyl, Aminoiminoamino-(Ci-C6)-alkyl, (Ci-C6) alkoxycarbonylamino (Ci-C6) alkyl, aryl (Ci-C6) alkoxycarbonylamino (Ci-CeJ-alkyl, (C3-C6) cycloalkyl (Ci-C6) alkoxycarbonylamino ( Ci-C6) alkyl, aminocarbonylamino (Ci-C-6) alkyl, Aminoiminoamino- (Ci-C6) alkyl,

Arylsulfonylaminoiminoamino-(Ci-C6)-alkyl, (Ci-C6)-Alkylaminoiminoamino- (Ci-Ce)-alkyl stehen, R 41 für H, (Ci-Ce)-Alkyl, (C 2 -Ce)-Alkenyl-(Ci-Ce)-alkyl, (C 2 -C 6 )-Alkinyl, (Ci-C 6 )- Alkylcarbonyl, (C3-C6)-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl, (Ci-C6)-Alkoxycarbonyl, Aryl-(Ci-C6)-alkoxycarbonyl, (C3-C6)- Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkoxycarbonyl, (C1-C6)- Alkylsulfonyl, (C3-C6)-Cycloalkylsulfonyl, Arylsulfonyl, (C1-C6)- Arylsulfonylaminoiminoamino- (Ci-C6) alkyl, (Ci-C6) -Alkylaminoiminoamino- (Ci-Ce) alkyl, R 41 is H, (Ci-Ce) alkyl, (C 2 -Ce) -alkenyl ( Ci-Ce) alkyl, (C2-C6) -alkynyl, (C 6) - alkylcarbonyl, (C3-C6) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl, (Ci-C6) alkoxycarbonyl, aryl (Ci C6) -alkoxycarbonyl, (C3-C6) - cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C6) -alkoxycarbonyl, (C1-C6) - alkylsulfonyl, (C3-C6) cycloalkylsulfonyl, arylsulphonyl, (C1 C6) -

Alkoxycarbonylcarbonyl, Aryl-(Ci-C6)-alkoxycarbonylcarbonyl, (C1-C6)- Alkylaminothiocarbonyl, (Ci-C6)-Alkylaminocarbonyl, Aryl-(Ci-C6)-alkyl, Hetaroaryl-(Ci-C 6 )-alkyl, Cyano-(Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkyl, (C 3 -C 6 )- Cycloalkyl, (C3-C 6 )-Cycloalkyl-(Ci-C 6 )-alkyl, (Ci-C 6 )-Alkoxy-(Ci-C 6 )-alkyl, Alkoxycarbonylcarbonyl, aryl (Ci-C6) -alkoxycarbonylcarbonyl, (C1-C6) - alkylaminothiocarbonyl, (Ci-C6) alkylaminocarbonyl, aryl (Ci-C6) alkyl, Hetaroaryl- (Ci-C 6) alkyl, cyano - (Ci-C 6) alkyl, (Ci-C 6) -haloalkyl, (C 3 -C 6) - cycloalkyl, (C3-C6) cycloalkyl (Ci-C 6) alkyl, (Ci- C 6) alkoxy- (Ci-C 6) alkyl,

(Ci-C 6 )-Haloalkoxy-(Ci-C 6 )-alkyl, (C2-C 6 )-Alkinyl-(Ci-C 6 )-alkyl, (Ci-C 6 )- (Ci-C 6) haloalkoxy (Ci-C 6) alkyl, (C2-C6) alkynyl (Ci-C 6) alkyl, (Ci-C 6) -

Alkoxycarbonyl-(Ci-C6)-alkyl, Aminocarbonyl-(Ci-C6)-alkyl, (C1-C6)- Alkylaminocarbonyl-(Ci-C6)-alkyl, Bis-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl steht, Alkoxycarbonyl (Ci-C6) alkyl, aminocarbonyl (Ci-C6) alkyl, (C1-C6) - alkylaminocarbonyl (Ci-C6) alkyl, bis (Ci-C6) alkylaminocarbonyl (Ci-C6 ) -alkyl,

im Falle der Gruppierung Q-21 ausschließlich für H oder Methyl steht, in the case of the group Q-21 is available exclusively for H or methyl,

R 42 für (C 2 -C 6 )-Alkyl, (C2-C 6 )-Alkenyl-(Ci-C 6 )-alkyl, (C 2 -C 6 )-Alkinyl, (Ci-C 6 )- R 42 is (C 2 -C 6) alkyl, (C2-C6) alkenyl (Ci-C 6) alkyl, (C 2 -C 6) alkynyl, (Ci-C 6) -

Alkylcarbonyl, (C3-C6)-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl, (Ci-C6)-Alkoxycarbonyl, Aryl-(Ci-C6)-alkoxycarbonyl, (C3-C6)- Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkoxycarbonyl, (C1-C6)- Alkylsulfonyl, (C 3 -C 6 )-Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C 6 )- Alkylcarbonyl, (C3-C6) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl, (Ci-C6) alkoxycarbonyl, aryl (Ci-C6) -alkoxycarbonyl, (C3-C6) - cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci C6) -alkoxycarbonyl, (C1-C6) - alkylsulfonyl, (C3-C6) cycloalkylsulfonyl, arylsulphonyl, (Ci-C 6) -

Alkoxycarbonylcarbonyl, Aryl-(Ci-C6)-alkoxycarbonylcarbonyl, (C1-C6)- Alkylaminothiocarbonyl, (Ci-C6)-Alkylaminocarbonyl, Aryl-(Ci-C6)-alkyl, Hetaroaryl-(Ci-C 6 )-alkyl, Cyano-(Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkyl, (C 3 -C 6 )- Cycloalkyl, (C3-C 6 )-Cycloalkyl-(Ci-C 6 )-alkyl, (Ci-C 6 )-Alkoxy-(Ci-C 6 )-alkyl, Alkoxycarbonylcarbonyl, aryl (Ci-C6) -alkoxycarbonylcarbonyl, (C1-C6) - alkylaminothiocarbonyl, (Ci-C6) alkylaminocarbonyl, aryl (Ci-C6) alkyl, Hetaroaryl- (Ci-C 6) alkyl, cyano - (Ci-C 6) alkyl, (Ci-C 6) -haloalkyl, (C 3 -C 6) - cycloalkyl, (C3-C6) cycloalkyl (Ci-C 6) alkyl, (Ci- C 6) alkoxy- (Ci-C 6) alkyl,

(Ci-C 6 )-Haloalkoxy-(Ci-C 6 )-alkyl, (C2-C 6 )-Alkinyl-(Ci-C 6 )-alkyl, (Ci-C 6 )- (Ci-C 6) haloalkoxy (Ci-C 6) alkyl, (C2-C6) alkynyl (Ci-C 6) alkyl, (Ci-C 6) -

Alkoxycarbonyl-(Ci-C6)-alkyl, Aminocarbonyl-(Ci-C6)-alkyl, (C1-C6)- Alkylaminocarbonyl-(Ci-C6)-alkyl, Bis-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl steht, R 43 für H oder Methyl steht, R 44 für Wasserstoff, (Ci -Ce)-Alkyl, (C 2 -Ce)-Alkenyl-(Ci -Ce)-alkyl, (C 2 -C 6 )-Alkinyl, (Ci -C6)-Alkylcarbonyl, (C3-C6)-Cycloalkylcarbonyl, Arylcarbonyl, Alkoxycarbonyl (Ci-C6) alkyl, aminocarbonyl (Ci-C6) alkyl, (C1-C6) - alkylaminocarbonyl (Ci-C6) alkyl, bis (Ci-C6) alkylaminocarbonyl (Ci-C6 ) alkyl, R 43 is H or methyl, R 44 is hydrogen, (Ci -Ce) alkyl, (C 2 -Ce) alkenyl (Ci -Ce) alkyl, (C 2 -C 6) alkynyl, (Ci-C6) alkylcarbonyl, (C3-C6) cycloalkylcarbonyl, arylcarbonyl,

Heteroarylcarbonyl, (Ci -C6)-Alkoxycarbonyl, Aryl-(Ci -C6)-alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci -C6)-alkoxycarbonyl, Heteroarylcarbonyl, (Ci-C6) alkoxycarbonyl, aryl (Ci-C6) -alkoxycarbonyl, (C3-C6) cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C6) -alkoxycarbonyl,

(Ci -Ce)-Alkylsulfonyl, (C 3 -C 6 )-Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C 6 )- (Ci -Ce) alkylsulfonyl, (C 3 -C 6) cycloalkylsulfonyl, arylsulfonyl, (Ci-C 6) -

Alkoxycarbonylcarbonyl, Aryl-(Ci -C6)-alkoxycarbonylcarbonyl, (C1 -C6)- Alkylaminothiocarbonyl, (Ci -C6)-Alkylaminocarbonyl, Aryl-(Ci -C6)-alkyl, Hetaroaryl-(Ci-C 6 )-alkyl, Cyano-(Ci-C 6 )-alkyl, (Ci-C 6 )-Haloalkyl, (C 3 -C 6 )- Cycloalkyl, (C3-C 6 )-Cycloalkyl-(Ci-C 6 )-alkyl, (Ci-C 6 )-Alkoxy-(Ci-C 6 )-alkyl, Alkoxycarbonylcarbonyl, aryl (Ci-C6) -alkoxycarbonylcarbonyl, (C1-C6) - alkylaminothiocarbonyl, (Ci-C6) alkylaminocarbonyl, aryl (Ci-C6) alkyl, Hetaroaryl- (Ci-C 6) alkyl, cyano - (Ci-C 6) alkyl, (Ci-C 6) -haloalkyl, (C 3 -C 6) - cycloalkyl, (C3-C6) cycloalkyl (Ci-C 6) alkyl, (Ci- C 6) alkoxy- (Ci-C 6) alkyl,

(Ci-C 6 )-Haloalkoxy-(Ci-C 6 )-alkyl, (C2-C 6 )-Alkinyl-(Ci-C 6 )-alkyl, (Ci-C 6 )- (Ci-C 6) haloalkoxy (Ci-C 6) alkyl, (C2-C6) alkynyl (Ci-C 6) alkyl, (Ci-C 6) -

Alkoxycarbonyl-(Ci -C6)-alkyl, Aminocarbonyl-(Ci -C6)-alkyl, (C1 -C6)- Alkylaminocarbonyl-(Ci -C6)-alkyl, Bis-(Ci -C6)-alkylaminocarbonyl-(Ci -C6)-alkyl steht, R 51 und R 71 unabhängig voneinander für Wasserstoff und Methyl stehen, R 53 für Methyl steht, Alkoxycarbonyl (Ci-C6) alkyl, aminocarbonyl (Ci-C6) alkyl, (C1-C6) - alkylaminocarbonyl (Ci-C6) alkyl, bis (Ci-C6) alkylaminocarbonyl (Ci-C6 ) -alkyl, R 51 and R 71 independently represent hydrogen and methyl, R 53 is methyl,

R 61 und R 81 unabhängig voneinander für Wasserstoff und Methyl stehen, R 61 and R 81 independently represent hydrogen and methyl,

R 63 für H, Methyl steht, R 63 is H, methyl,

R 54 , R 64 , R 74 , R 84 unabhängig voneinander für Wasserstoff, Methyl stehen, wobei mindestens eine der Gruppen R 54 , R 64 , R 74 , R 84 für Methyl stehen muß, R 54, R 64, R 74, R 84 are independently hydrogen, methyl, where at least one of R 54, R 64, R 74, R 84 must be methyl,

V für Hydroxycarbonyl, (Ci -C6)-Alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci -C6)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci -Ce)- alkoxycarbonyl, Aminocarbonyl, (Ci -C6)-Alkylaminocarbonyl, Bis-(Ci -Ce)- alkylaminocarbonyl, (Ci -C6)-Alkyl[(Ci -C6)-Alkoxy]aminocarbonyl, (C3-C6)- Cycloalkylaminocarbonyl, Aryl-(Ci -C6)-alkylaminocarbonyl, Heteroaryl-(Ci -C6)- alkylaminocarbonyl, Cyano-(Ci -C6)-alkylaminocarbonyl, (C1 -C6)- Haloalkylaminocarbonyl, (C2-C6)-Alkinyl-(Ci -C6)-alkylaminocarbonyl, (C1 -C6)- Alkoxycarbonyl-(Ci-C6)-alkylaminocarbonyl, Hydroxycarbonyl-(Ci-C6)- alkylaminocarbonyl, Aminocarbonyl-(Ci-C6)-alkylaminocarbonyl, (C1-C6)- Alkylaminocarbonyl-(Ci-C6)-alkylaminocarbonyl, (C3-C6)- Cycloalkylaminocarbonyl-(Ci-C6)-alkylaminocarbonyl, (C3-C6)-Cycloalkyl- (Ci-C6)-alkylaminocarbonyl steht, m für 0, 1 , 2, 3, 4, 5 steht, p für 1 , 2, 3, 4 steht, V hydroxycarbonyl, (Ci-C6) -alkoxycarbonyl, (C3-C6) cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C6) alkoxycarbonyl, aryloxycarbonyl, aryl (Ci -Ce) - alkoxycarbonyl, aminocarbonyl, (Ci-C6) alkylaminocarbonyl, bis (Ci -Ce) - alkylaminocarbonyl, (Ci-C6) alkyl [(Ci-C6) alkoxy] aminocarbonyl, (C3-C6) - cycloalkylaminocarbonyl, aryl (Ci-C6 ) alkylaminocarbonyl, heteroaryl (Ci-C6) - alkylaminocarbonyl, cyano (Ci-C6) alkylaminocarbonyl, (C1-C6) - Haloalkylaminocarbonyl, (C2-C6) alkynyl (Ci-C6) alkylaminocarbonyl, (C1 C6) - alkoxycarbonyl (Ci-C6) alkylaminocarbonyl, hydroxycarbonyl (Ci-C6) - alkylaminocarbonyl, aminocarbonyl (Ci-C6) alkylaminocarbonyl, (C1-C6) - alkylaminocarbonyl (Ci-C6) alkylaminocarbonyl, (C3-C6) - cycloalkylaminocarbonyl (Ci-C6) alkylaminocarbonyl, (C3-C6) cycloalkyl (Ci-C6) alkylaminocarbonyl, m is 0, 1, 2, 3, 4, 5, p is for 1, 2, 3, 4 is available,

Y für Cyano, Cyano-(Ci-C 6 )-alkyl, Hydroxy-(Ci-C 6 )-alkyl, (Ci-C 6 )-Alkoxy-(Ci-C 6 )- alkyl, Hydroxycarbonyl, (Ci-C6)-Alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-Ce)- alkoxycarbonyl, Aminocarbonyl, (Ci-C6)-Alkylaminocarbonyl, Bis-(Ci-Ce)- alkylaminocarbonyl, (Ci-C6)-Alkyl[(Ci-C6)-Alkoxy]aminocarbonyl, (C3-C6)- Cycloalkylaminocarbonyl, Aryl-(Ci-C6)-alkylaminocarbonyl, Heteroaryl-(Ci-C6)- alkylaminocarbonyl, Cyano-(Ci-C6)-alkylaminocarbonyl, (C1-C6)- Haloalkylaminocarbonyl, (C2-C6)-Alkinyl-(Ci-C6)-alkylaminocarbonyl, (C1-C6)- Alkoxycarbonylaminocarbonyl, Aryl-(Ci-C6)-alkoxycarbonylaminocarbonyl, Hydroxycarbonyl-(Ci-C6)-alkyl, (Ci-C6)-Alkoxycarbonyl-(Ci-C6)-alkyl, (C3-C6)- Cycloalkoxycarbonyl-(Ci-C6)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkoxycarbonyl- (Ci-C6)-alkyl, (Ci-C6)-Alkylaminocarbonyl-(Ci-C6)-alkyl, Aminocarbonyl- (Ci-Ce)-alkyl, Bis-(Ci-C 6 )-alkylaminocarbonyl-(Ci-C 6 )-alkyl, (C 3 -C 6 )- Cycloalkylaminocarbonyl-(Ci-C6)-alkyl, Aryl-(Ci-C6)-alkylaminocarbonyl- (Ci-C6)-alkyl, Heteroaryl-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, Cyano- (Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl, (Ci-C6)-Haloalkylaminocarbonyl- (Ci-Ce)-alkyl, (C2-Ce)-Alkinyl-(Ci-Ce)-alkylaminocarbonyl-(Ci-Ce)-alkyl, (C3-Ce)-Cycloalkyl-(Ci-Ce)-alkylaminocarbonyl-(Ci-Ce)-alkyl, (Ci-C 6 )- Alkoxycarbonylaminocarbonyl-(Ci-C6)-alkyl, Aryl-(Ci-Ce)- alkoxycarbonylaminocarbonyl-(Ci-C6)-alkyl, Y is cyano, cyano (Ci-C 6) alkyl, hydroxy (Ci-C 6) alkyl, (Ci-C 6) alkoxy (Ci-C 6) - alkyl, hydroxycarbonyl, (Ci-C6 ) -alkoxycarbonyl, (C3-C6) cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C6) alkoxycarbonyl, aryloxycarbonyl, aryl (Ci-Ce) - alkoxycarbonyl, aminocarbonyl, (Ci-C6) alkylaminocarbonyl, bis (Ci-Ce) - alkylaminocarbonyl, (Ci-C6) alkyl [(Ci-C6) alkoxy] aminocarbonyl, (C3-C6) - cycloalkylaminocarbonyl, aryl (Ci-C6) alkylaminocarbonyl, heteroaryl- (Ci C6) - alkylaminocarbonyl, cyano (Ci-C6) alkylaminocarbonyl, (C1-C6) - Haloalkylaminocarbonyl, (C2-C6) alkynyl (Ci-C6) alkylaminocarbonyl, (C1-C6) - Alkoxycarbonylaminocarbonyl, aryl (Ci-C6) -alkoxycarbonylaminocarbonyl, hydroxycarbonyl (Ci-C6) alkyl, (Ci-C6) -alkoxycarbonyl (Ci-C6) alkyl, (C3-C6) - Cycloalkoxycarbonyl- (Ci-C6) alkyl, (C3-C6) cycloalkyl (Ci-C6) -alkoxycarbonyl (Ci-C6) alkyl, (Ci-C6) alkylaminocarbonyl (Ci-C6) alkyl, aminocarbonyl (Ci-Ce) alkyl, bis (Ci-C6) alkylaminocarbonyl (Ci-C 6) alkyl, (C 3 -C 6) - cycloalkylaminocarbonyl (Ci-C6) alkyl, aryl (Ci-C6) alkylaminocarbonyl (Ci C6) alkyl, heteroaryl (Ci-C6) alkylaminocarbonyl (Ci-C6) alkyl, cyano (Ci-C6) alkylaminocarbonyl (Ci-C6) alkyl, (Ci-C6) -Haloalkylaminocarbonyl- (Ci-Ce) alkyl, (C2-Ce) alkynyl (Ci-Ce) alkylaminocarbonyl (Ci-Ce) alkyl, (C3-Ce) cycloalkyl (Ci-Ce) alkylaminocarbonyl (Ci -ce) alkyl, (Ci-C 6) - Alkoxycarbonylaminocarbonyl- (Ci-C6) alkyl, aryl (Ci-Ce) - alkoxycarbonylaminocarbonyl- (Ci-C6) alkyl,

(Ci-C6)-Alkoxycarbonyl-(Ci-C6)-alkylaminocarbonyl, Hydroxycarbonyl-(Ci-C6)- alkylaminocarbonyl, Aminocarbonyl-(Ci-C6)-alkylaminocarbonyl, (C1-C6)- Alkylaminocarbonyl-(Ci-C6)-alkylaminocarbonyl, (C3-C6)- Cycloalkylaminocarbonyl-(Ci-C6)-alkylaminocarbonyl, (C3-C6)-Cycloalkyl- (Ci-C6)-alkylaminocarbonyl, (C3-C6)-Cycloalkyl-(Ci-C6)-alkylaminocarbonyl- (Ci-C6)-alkyl, (C2-C6)-Alkenyloxycarbonyl, (C2-C6)-Alkenyloxycarbonyl-(Ci-C6)- alkyl, (C2-C6)-Alkenylaminocarbonyl, (C2-C6)-Alkenyl-(Ci-C6)- alkylaminocarbonyl, (C2-C6)-Alkenylaminocarbonyl-(Ci-C6)-alkyl, (C2-C6)- Alkenyl-(Ci-C6)-alkylaminocarbonyl-(Ci-C6)-alkyl steht. (Ci-C6) -alkoxycarbonyl (Ci-C6) alkylaminocarbonyl, hydroxycarbonyl (Ci-C6) - alkylaminocarbonyl, aminocarbonyl (Ci-C6) alkylaminocarbonyl, (C1-C6) - alkylaminocarbonyl (Ci-C6) - alkylaminocarbonyl, (C3-C6) - cycloalkylaminocarbonyl (Ci-C6) alkylaminocarbonyl, (C3-C6) cycloalkyl (Ci-C6) alkylaminocarbonyl, (C3-C6) cycloalkyl (Ci-C6) -alkylaminocarbonyl- (Ci-C6) alkyl, (C2-C6) alkenyloxycarbonyl, (C2-C6) -Alkenyloxycarbonyl- (Ci-C6) - alkyl, (C2-C6) -Alkenylaminocarbonyl, (C2-C6) -alkenyl (Ci C6) - alkylaminocarbonyl, (C2-C6) -Alkenylaminocarbonyl- (Ci-C6) alkyl, (C2-C6) - alkenyl (Ci-C6) alkylaminocarbonyl (Ci-C6) alkyl.

Besonders bevorzugt ist die erfindungsgemäße Verwendung von Verbindungen der allgemeinen Formel (I), worin Particularly preferably, the inventive use of compounds of general formula (I) wherein

Figure imgf000032_0001
zur Toleranzerhöhung gegenüber abiotischem Stress in Pflanzen, worin to increase tolerance to abiotic stress in plants, wherein

Q für die Gruppierungen Q represents the groups

Figure imgf000032_0002

Q-22 Q-23 Q-24 steht, und wobei die Reste R 4 bis R 8 , und R 41 bis R 84 sowie Y und m und p jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zum Schwefelatom der S02-Gruppe steht; Q-22 Q-23 Q-24 is, and where the radicals R 4 to R 8 and R 41 to R 84 and Y and m and p are each as defined in accordance with the following definitions and where the arrow represents a bond to the sulfur atom the S02 group;

A 1 , A 2 , A 3 gleich oder verschieden sind und unabhängig voneinander für N A 1, A 2, A 3 are identical or different and are each independently N

(Stickstoff) oder die Gruppierung CW stehen, wobei jedoch in keinem Fall mehr als zwei N-Atome benachbart sind, und wobei W in der Gruppierung C- W jeweils gleiche oder verschiedene Bedeutungen gemäß der (Nitrogen) or the group CW are, but in no case more than two N atoms are adjacent, and wherein W in the group C- W are identical or different meanings in accordance with the

nachstehenden Definition hat, definition below has,

W jeweils für Wasserstoff, Nitro, Amino, Cyano, Thiocyanato, Isothiocyanato, Halogen, (Ci-C 4 )-Alkyl, (C 3 -C 6 )-Cycloalkyl, (C 2 -C 4 )-Alkenyl, (C 2 -C 4 )-Alkinyl, Aryl, Aryl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkoxy, Heteroaryl, (Ci-C 4 )-Alkoxy- (Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, (C 3 -C 5 )-Halocycloalkyl, (Ci-C 4 )-Alkoxy, (Ci-C 4 )-Haloalkoxy, Aryloxy, Heteroaryloxy, (C3-C6)-Cycloalkyloxy, (C3-C6)- Cycloalkyl-(Ci-C 4 )-alkoxy, (Ci-C 4 )-Alkoxycarbonyl, (Ci-C 4 )-Alkoxycarbonyl- (Ci-C 4 )-alkyl, Hydroxycarbonyl, Aminocarbonyl, (Ci-C 4 )-Alkylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Cyano-(Ci-C 4 )-alkylaminocarbonyl, (C2-C 4 )- Alkenylaminocarbonyl, (C2-C 4 )-Alkinylaminocarbonyl, (Ci-C 4 )-Alkylamino, (Ci-C 4 )-Alkylthio, (Ci-C 4 )-Haloalkylthio, Bis-(Ci-C 4 )-alkylamino, (C 3 -C 6 )- Cycloalkylamino, (Ci-C 4 )-Alkylcarbonylamino, (C3-C6)- Cycloalkylcarbonylamino, Formylamino, (Ci-C 4 )-Haloalkylcarbonylamino, (Ci-C 4 )-Alkoxycarbonylamino, (Ci-C 4 )-Alkylaminocarbonylamino, Bis-[(Ci-C 4 )- Alkylj-aminocarbonyl-amino, (Ci-C 4 )-Alkylsulfonylamino, (C3-C6)- Cycloalkylsulfonylamino, Arylsulfonylamino, Hetarylsulfonylamino, Sulfonyl- (Ci-C 4 )-haloalkylamino, Amino-(Ci-C 4 )-alkylsulfonyl, Amino-(Ci-C 4 )- haloalkylsulfonyl, (Ci-C 4 )-Alkylsulfonyl, (C3-C6)-Cycloalkylsulfonyl, W each represent hydrogen, nitro, amino, cyano, thiocyanato, isothiocyanato, halogen, (Ci-C 4) -alkyl, (C 3 -C 6) -cycloalkyl, (C 2 -C 4) alkenyl, (C 2 - C 4) -alkynyl, aryl, aryl- (Ci-C 4) alkyl, aryl (Ci-C 4) alkoxy, heteroaryl, (Ci-C 4) alkoxy (Ci-C 4) alkyl, (Ci-C4) -haloalkyl, (C 3 -C 5) halocycloalkyl, (Ci-C4) -alkoxy, (Ci-C4) haloalkoxy, aryloxy, heteroaryloxy, (C3-C6) -cycloalkyloxy, ( C3-C6) - cycloalkyl (Ci-C4) -alkoxy, (Ci-C4) alkoxycarbonyl, (Ci-C4) alkoxycarbonyl (Ci-C4) alkyl, hydroxycarbonyl, aminocarbonyl, (Ci C4) alkylaminocarbonyl, (C3-C6) cycloalkylaminocarbonyl, cyano (Ci-C4) alkylaminocarbonyl, (C2-C4) - alkenylaminocarbonyl, (C2-C4) -Alkinylaminocarbonyl, (Ci-C4) - alkylamino, (Ci-C4) -alkylthio, (C 4) haloalkylthio, bis (Ci-C4) alkylamino, (C3-C6) - cycloalkylamino, (Ci-C 4) alkylcarbonylamino, (C3-C6) - cycloalkylcarbonylamino, formylamino, (Ci-C4) -Haloalkylcarbonylamino, (Ci-C4) alkoxycarbonylamino, (Ci-C4) alkylaminocarbonylamino, bis - [(Ci-C4) - Alkylj-aminocarbonyl amino, (Ci-C4) alkylsulfonylamino, (C3-C6) - cycloalkylsulfonylamino, arylsulfonylamino, Hetarylsulfonylamino, sulfonyl (Ci-C4) -haloalkylamino, amino (Ci-C4) alkylsulphonyl, amino (Ci C4) - haloalkylsulfonyl, (Ci-C4) alkylsulphonyl, (C3-C6) cycloalkylsulfonyl,

Arylsulfonyl, (Ci-C 4 )-Alkylsulfinyl, (C 3 -C 6 )-Cycloalkylsulfinyl, Arylsulfinyl, N,S- Di-(Ci-C 4 )-alkylsulfonimidoyl, S-(Ci-C 4 )-Alkylsulfonimidoyl, (Ci-C 4 )- Alkylsulfonylaminocarbonyl, (C3-C6)-Cycloalkylsulfonylaminocarbonyl, (C3-C6)- Cycloalkylaminosulfonyl, Aryl-(Ci-C 4 )-alkylcarbonylamino, (C3-C6)-Cycloalkyl- (Ci-C 4 )-alkylcarbonylamino, Heteroarylcarbonylamino, (Ci-C 4 )-Alkoxy-(Ci-C 4 )- alkylcarbonylamino, Hydroxy-(Ci-C 4 )-alkylcarbonylamino steht, Arylsulfonyl, (Ci-C4) alkylsulfinyl, (C3-C6) -Cycloalkylsulfinyl, arylsulfinyl, N, S di (Ci-C4) -alkylsulfonimidoyl, S- (Ci-C4) -Alkylsulfonimidoyl, ( Ci-C4) - alkylsulphonylaminocarbonyl, (C3-C6) -Cycloalkylsulfonylaminocarbonyl, (C3-C6) - Cycloalkylaminosulfonyl, aryl (Ci-C 4) alkylcarbonylamino, (C3-C6) cycloalkyl (Ci-C4) - alkylcarbonylamino, heteroarylcarbonylamino, (Ci-C4) alkoxy (Ci-C4) - alkylcarbonylamino, hydroxy (Ci-C4) is alkylcarbonylamino,

R 1 für H, Nitro, Amino, Cyano, Halogen, (Ci-C 4 )-Alkyl, (C 3 -C 6 )-Cycloalkyl, R 1 is H, nitro, amino, cyano, halogen, (Ci-C 4) alkyl, (C 3 -C 6) -cycloalkyl,

(C 2 -C 4 )-Alkenyl, (C 2 -C 4 )-Alkinyl, Aryl, Aryl-(Ci-C 4 )-alkyl, Heteroaryl, (Ci-C 4 )- Alkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, (C 3 -C 6 )-Halocycloalkyl, (Ci-C 4 )-Alkoxy, (Ci-C 4 )-Haloalkoxy, (Ci-C 4 )-Alkylthio, (Ci-C 4 )-Haloalkylthio, (Ci-C 4 )- Alkoxycarbonyl, Hydroxycarbonyl, Aminocarbonyl, (Ci-C 4 )- Alkylaminocarbonyl, (Ci-C 4 )-Alkylamino, Bis-(Ci-C 4 )-alkylamino, (C3-C6)- Cycloalkylamino, (Ci-C 4 )-Alkylcarbonylamino, (C3-C6)- Cycloalkylcarbonylamino, Formylamino, (Ci-C 4 )-Haloalkylcarbonylamino, (Ci-C 4 )-Alkoxycarbonylamino, [(Ci-C 4 )-Alkyl-]aminocarbonyl-amino, (C 2 -C 4) -alkenyl, (C 2 -C 4) -alkynyl, aryl, aryl- (Ci-C 4) alkyl, heteroaryl, (Ci-C4) - alkoxy- (Ci-C 4) alkyl, (Ci-C4) -haloalkyl, (C3-C6) halocycloalkyl, (Ci-C4) -alkoxy, (Ci-C4) haloalkoxy, (Ci-C4) -alkylthio, ( Ci-C 4) haloalkylthio, (Ci-C4) - alkoxycarbonyl, hydroxycarbonyl, aminocarbonyl, (Ci-C4) - alkylaminocarbonyl, (Ci-C4) alkylamino, bis (Ci-C4) alkylamino, (C3-C6) - cycloalkylamino, (Ci-C 4) alkylcarbonylamino, (C3-C6) - cycloalkylcarbonylamino, formylamino, (Ci-C4) -Haloalkylcarbonylamino, (Ci-C4) alkoxycarbonylamino, [(C 4) -alkyl] aminocarbonyl-amino,

Sulfonylamino, (Ci-C 4 )-Alkylsulfonylamino, (Ci-C 4 )-Haloalkylsulfonylamino, (C3-C6)-Cycloalkylsulfonylamino, Amino-(Ci-C 4 )-alkylsulfonyl, Amino-(Ci-C 4 )- haloalkylsulfonyl, (Ci-C 4 )-Alkylsulfonyl, (C3-C6)-Cycloalkylsulfonyl, Sulfonylamino, (Ci-C4) alkylsulfonylamino, (Ci-C4) -Haloalkylsulfonylamino, (C3-C6) -Cycloalkylsulfonylamino, amino (Ci-C4) alkylsulphonyl, amino (Ci-C4) - haloalkylsulfonyl, (Ci-C4) alkylsulphonyl, (C3-C6) cycloalkylsulfonyl,

Arylsulfonyl, (Ci-C 4 )-Alkylsulfinyl, (C 3 -C 6 )-Cycloalkylsulfinyl, Arylsulfinyl, N,S- Di-(Ci-C 4 )-alkylsulfonimidoyl, S-(Ci-C 4 )-Alkylsulfonimidoyl, (Ci-C 4 )- Alkylsulfonylaminocarbonyl, (C3-C6)-Cycloalkylsulfonylaminocarbonyl, (C3-C6)- Cycloalkylaminosulfonyl, Amino-(Ci-C 4 )-alkyl, Amino-(C2-C 4 )-alkenyl, (C2-C 4 )- Alkenylamino, (C2-C 4 )-Alkenylimino steht, Arylsulfonyl, (Ci-C4) alkylsulfinyl, (C3-C6) -Cycloalkylsulfinyl, arylsulfinyl, N, S di (Ci-C4) -alkylsulfonimidoyl, S- (Ci-C4) -Alkylsulfonimidoyl, ( Ci-C4) - alkylsulphonylaminocarbonyl, (C3-C6) -Cycloalkylsulfonylaminocarbonyl, (C3-C6) - Cycloalkylaminosulfonyl, amino (Ci-C4) alkyl, amino (C2-C4) -alkenyl, (C2-C 4) - alkenylamino, (C2-C4) -Alkenylimino stands,

R 2 für H, Nitro, Amino, Cyano, Halogen, (Ci-C 4 )-Alkyl, (C 3 -C 6 )-Cycloalkyl, R 2 is H, nitro, amino, cyano, halogen, (Ci-C 4) alkyl, (C 3 -C 6) -cycloalkyl,

(C 2 -C 4 )-Alkenyl, (C 2 -C 4 )-Alkinyl, Aryl, Aryl-(Ci-C 4 )-alkyl, Heteroaryl, (Ci-C 4 )- Alkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, (C 3 -C 6 )-Halocycloalkyl, (Ci-C 4 )-Alkoxy, (Ci-C 4 )-Haloalkoxy, (Ci-C 4 )-Alkylthio, (Ci-C 4 )-Haloalkylthio, (Ci-C 4 )- Alkoxycarbonyl, Hydroxycarbonyl, Aminocarbonyl, (Ci-C 4 )- Alkylaminocarbonyl, (Ci-C 4 )-Alkylamino, Bis-(Ci-C 4 )-alkylamino, (C3-C6)- Cycloalkylamino, (Ci-C 4 )-Alkylcarbonylamino, (C3-C6)- Cycloalkylcarbonylamino, Formylamino, (Ci-C 4 )-Haloalkylcarbonylamino, (Ci-C 4 )-Alkoxycarbonylamino, [(Ci-C 4 )-Alkyl-]-aminocarbonyl-amino, (C 2 -C 4) -alkenyl, (C 2 -C 4) -alkynyl, aryl, aryl- (Ci-C 4) alkyl, heteroaryl, (Ci-C4) - alkoxy- (Ci-C 4) alkyl, (Ci-C4) -haloalkyl, (C3-C6) halocycloalkyl, (Ci-C4) -alkoxy, (Ci-C4) haloalkoxy, (Ci-C4) -alkylthio, ( Ci-C 4) haloalkylthio, (Ci-C4) - alkoxycarbonyl, hydroxycarbonyl, aminocarbonyl, (Ci-C4) - alkylaminocarbonyl, (Ci-C4) alkylamino, bis (Ci-C4) alkylamino, (C3-C6) - cycloalkylamino, (Ci-C 4) alkylcarbonylamino, (C3-C6) - cycloalkylcarbonylamino, formylamino, (Ci-C4) -Haloalkylcarbonylamino, (Ci-C4) alkoxycarbonylamino, [(C 4) -alkyl -] - aminocarbonyl-amino,

Sulfonylamino, (Ci-C 4 )-Alkylsulfonylamino, (Ci-C 4 )-Haloalkylsulfonylamino, (C3-C6)-Cycloalkylsulfonylamino, Amino-(Ci-C 4 )-alkylsulfonyl, Amino-(Ci-C 4 )- haloalkylsulfonyl, (Ci-C 4 )-Alkylsulfonyl, (C3-C6)-Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C 4 )-Alkylsulfinyl, (C 3 -C 6 )-Cycloalkylsulfinyl, Arylsulfinyl, N,S- Di-(Ci-C 4 )-alkylsulfonimidoyl, S-(Ci-C 4 )-Alkylsulfonimidoyl, (Ci-C 4 )- Alkylsulfonylaminocarbonyl, (C3-C6)-Cycloalkylsulfonylaminocarbonyl, (C3-C6)- Cycloalkylaminosulfonyl, Amino-(Ci-C 4 )-alkyl, Amino-(C2-C 4 )-alkenyl, (C2-C 4 )- Sulfonylamino, (Ci-C4) alkylsulfonylamino, (Ci-C4) -Haloalkylsulfonylamino, (C3-C6) -Cycloalkylsulfonylamino, amino (Ci-C4) alkylsulphonyl, amino (Ci-C4) - haloalkylsulfonyl, (Ci-C4) alkylsulphonyl, (C3-C6) cycloalkylsulfonyl, arylsulphonyl, (Ci-C4) alkylsulfinyl, (C3-C6) -Cycloalkylsulfinyl, arylsulfinyl, N, S di- (Ci-C 4) -alkylsulfonimidoyl, S- (Ci-C4) -Alkylsulfonimidoyl, (Ci-C4) - alkylsulphonylaminocarbonyl, (C3-C6) -Cycloalkylsulfonylaminocarbonyl, (C3-C6) - Cycloalkylaminosulfonyl, amino (Ci-C4) - alkyl, amino (C2-C4) alkenyl, (C2-C 4) -

Alkenylamino, (C2-C 4 )-Alkenylimino steht, Alkenylamino, (C2-C4) -Alkenylimino stands,

R 1 und R 2 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten, teilgesättigten oder vollständig ungesättigten, gegebenenfalls durch R 1 and R 2 with the atoms to which they are attached form a fully saturated, partially saturated or fully unsaturated, optionally substituted by

Heteroatome unterbrochenen und gegebenenfalls weiter durch W Heteroatoms and optionally further interrupted by W

substituierten 5 bis 7-gliedrigen Ring bilden, und wobei sie im Falle der Verbindungen der allgemeinen Formel (I) mit den Gruppierungen Q-21 und Q- 23 einen entsprechenden Ring bilden müssen. substituted 5 to 7-membered ring, and being (I) to form with the moieties Q-21 and Q 23, a corresponding ring in the case of compounds of the general formula.

R 1 und A 3 , wenn A 3 für eine Gruppe CW steht, mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten, teilgesättigten oder vollständig R 1 and A 3, when A 3 is a group CW, with the atoms to which they are attached form a fully saturated, partially saturated or fully

ungesättigten, gegebenenfalls durch Heteroatome unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, für eine direkte Bindung oder für eine Gruppierung (CHR 3 ) n steht, und wobei R 3 in der Gruppierung (CHR 3 ) n jeweils gleiche oder verschiedene unsaturated, optionally interrupted by hetero atoms and optionally further substituted 5 form to 7-membered ring, a direct bond or is a group (CHR 3) n and wherein R 3 in the group (CHR 3) n are identical or different

Bedeutungen gemäß der nachstehenden Definition hat, n für 0, 1 steht Meanings as defined below, has n is 0, 1 is

R 3 für H, (Ci-C 4 )-Alkyl, (C 2 -C 4 )-Alkenyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, (C 3 -C 6 )- Cycloalkyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkyl, Heteroaryl- (Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylthio-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkylthio-(Ci-C 4 )-alkyl steht, R 3 is H, (Ci-C 4) -alkyl, (C 2 -C 4) alkenyl (Ci-C 4) alkyl, (Ci-C 4) -haloalkyl, (C 3 -C 6) - cycloalkyl, (C 3 -C 6) cycloalkyl (Ci-C 4) alkyl, aryl (Ci-C 4) -alkyl, heteroaryl- (Ci-C 4) alkyl, (Ci-C 4) - alkoxy (Ci-C4) alkyl, (Ci-C4) haloalkoxy (Ci-C4) alkyl, (Ci-C4) alkylthio (Ci-C4) alkyl, (Ci C 4) -Haloalkylthio- (Ci-C 4) -alkyl,

R 4 für H, (Ci-C 4 )-Alkyl, (C 2 -C 4 )-Alkenyl-(Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkinyl, (Ci-C 4 )- Alkylcarbonyl, (C3-C6)-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl, (Ci-C 4 )-Alkoxycarbonyl, Aryl-(Ci-C 4 )-alkoxycarbonyl, (C3-C6)- Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkoxycarbonyl, (Ci-C 4 )- Alkylsulfonyl, (C3-C6)-Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C 4 )- Alkoxycarbonylcarbonyl, Aryl-(Ci-C 4 )-alkoxycarbonylcarbonyl, (Ci-C 4 )- Alkylaminothiocarbonyl, (Ci-C 4 )-Alkylaminocarbonyl, Aryl-(Ci-C 4 )-alkyl, Hetaroaryl-(Ci-C 4 )-alkyl, Cyano-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, (C 3 -C 6 )- Cycloalkyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, R 4 is H, (Ci-C 4) -alkyl, (C 2 -C 4) alkenyl (Ci-C 4) alkyl, (C 2 -C 4) alkynyl, (Ci-C 4) - alkylcarbonyl, (C3-C6) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl, (Ci-C4) alkoxycarbonyl, aryl (Ci-C4) -alkoxycarbonyl, (C3-C6) - cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C4) -alkoxycarbonyl, (Ci-C4) - alkylsulfonyl, (C3-C6) cycloalkylsulfonyl, arylsulphonyl, (Ci-C4) - alkoxycarbonylcarbonyl, aryl (Ci-C4) -alkoxycarbonylcarbonyl, (Ci C4) - alkylaminothiocarbonyl, (Ci-C4) alkylaminocarbonyl, aryl (Ci-C4) alkyl, Hetaroaryl- (Ci-C4) alkyl, cyano (Ci-C4) alkyl, ( Ci-C 4) -haloalkyl, (C 3 -C 6) - cycloalkyl, (C 3 -C 6) cycloalkyl (Ci-C 4) alkyl, (Ci-C 4) alkoxy (Ci-C 4) alkyl,

(Ci-C 4 )-Haloalkoxy-(Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkinyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkoxycarbonyl-(Ci-C 4 )-alkyl, Aminocarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylaminocarbonyl-(Ci-C 4 )-alkyl, Bis-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl steht, für Halogen, (C2-C 4 )-Alkyl, (Ci-C 4 )-Alkoxy, (Ci-C 4 )-Alkoxycarbonyloxy, (C 2 -C 4 )-Alkenyl, (C 2 -C 4 )-Haloalkenyl, (C 2 -C 4 )-Alkenyl-(Ci-C 4 )-alkyl, (C 2 -C 4 )- Alkinyl, (C 2 -C 4 )-Alkinyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkyl, Bisaryl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkoxyaryl-(Ci-C 4 )-alkyl, Aryloxyaryl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkoxyaryl-(Ci-C 4 )-alkyl, Heteroaryl-(Ci-C 4 )-alkyl, Heterocyclyl-(Ci-C 4 )-alkyl, N-(Ci-C 4 )-Alkylheterocyclyl-(Ci-C 4 )-alkyl, N-[(Ci-C 4 )- Alkoxycarbonyl]heterocyclyl-(Ci-C 4 )-alkyl, N-(Aryl-(Ci-C 4 )- alkoxycarbonyl)heterocyclyl-(Ci-C 4 )-alkyl, N-(Arylcarbonyl)heterocyclyl- (Ci-C 4 )-alkyl, N-[(Ci-C 4 )-Alkylcarbonyl]heterocyclyl-(Ci-C 4 )-alkyl, N-[(C 3 -C 6 )- Cycloalkylcarbonyl]heterocyclyl-(Ci-C 4 )-alkyl, Cyano-(Ci-C 4 )-alkyl, (Ci-C 4 )- Haloalkyl, (C 3 -C 6 )-Cycloalkyl, (C 3 -C 6 )-Halocycloalkyl, (C 4 -C 6 )-Cycloalkenyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkenyl-(Ci-C 4 )-alkyl, Hydroxy- (Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkoxy-(Ci-C 4 )-alkyl, Aryloxy-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkoxy-(Ci-C 4 )-alkyl, Heteroaryl-(Ci-C 4 )- alkoxy-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkoxy-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkyl- (Ci-C 4 )-alkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylcarbonyloxy-(Ci-C 4 )-alkyl, (Ci-C4) haloalkoxy (Ci-C4) alkyl, (C2-C4) alkynyl (Ci-C4) alkyl, (Ci-C4) - alkoxycarbonyl (C 4) alkyl, aminocarbonyl (Ci-C 4) alkyl, (Ci-C4) - alkylaminocarbonyl (Ci-C 4) alkyl, bis (Ci-C4) alkylaminocarbonyl (Ci-C 4 ) -alkyl, halogen, (C2-C 4) alkyl, (Ci-C 4) alkoxy, (Ci-C4) alkoxycarbonyloxy, (C 2 -C 4) alkenyl, (C 2 -C 4) haloalkenyl, (C 2 -C 4) alkenyl, (Ci-C 4) alkyl, (C 2 -C 4) - alkynyl, (C 2 -C 4) alkynyl (Ci-C 4) alkyl, aryl (Ci-C4) alkyl, bisaryl (Ci-C4) alkyl, aryl (Ci-C4) -alkoxyaryl- (Ci-C4) alkyl, Aryloxyaryl- (Ci C 4) alkyl, (Ci-C 4) - alkoxyaryl (Ci-C 4) -alkyl, heteroaryl- (Ci-C 4) alkyl, heterocyclyl (Ci-C 4) alkyl, N- (Ci C4) -Alkylheterocyclyl- (Ci-C4) alkyl, N - [(Ci-C4) - alkoxycarbonyl] heterocyclyl (Ci-C4) alkyl, N- (aryl (Ci-C4) - alkoxycarbonyl) heterocyclyl (Ci-C4) alkyl, N- (arylcarbonyl) heterocyclyl (Ci-C4) alkyl, N - [(Ci-C4) alkyl-carbonyl] heterocyclyl (Ci-C4) alkyl, N - [(C 3 -C 6) - cycloalkylcarbonyl] heterocyclyl (Ci-C 4) alkyl, cyano (Ci-C 4) alkyl, (Ci-C4) - haloalkyl, (C 3 -C 6) -cycloalkyl, (C 3 -C 6) halocycloalkyl, (C 4 -C 6) -cycloalkenyl, (C 3 -C 6) cycloalkyl (Ci-C 4) alkyl, (C 3 - C 6) cycloalkenyl (Ci-C 4) alkyl, hydroxy (Ci-C 4) alkyl, (Ci-C 4) alkoxy (Ci-C 4) alkyl, (Ci-C 4) haloalkoxy (Ci-C 4) alkyl, aryloxy (Ci-C 4) alkyl, aryl (Ci-C 4) alkoxy (Ci-C 4) -alkyl, heteroaryl- (Ci-C 4 ) - alkoxy- (Ci-C 4) alkyl, (C 3 -C 6) cycloalkoxy (Ci-C 4) alkyl, (C 3 -C 6) cycloalkyl (Ci-C 4) alkoxy - (Ci-C 4) alkyl, (Ci-C 4) alkylcarbonyloxy (Ci-C 4) alkyl,

Arylcarbonyloxy-(Ci-C 4 )-alkyl, Heteroarylcarbonyloxy-(Ci-C 4 )-alkyl, (C3-C6)- Cycloalkylcarbonyloxy-(Ci-C 4 )-alkyl, Arylsulfonyloxy-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylsulfonyloxy-(Ci-C 4 )-alkyl, Hydrothio-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylthio- (Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkylthio-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkylthio- (Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkylthio-(Ci-C 4 )-alkyl, Arylthio-(Ci-C 4 )-alkyl, Arylcarbonyloxy (Ci-C4) alkyl, Heteroarylcarbonyloxy- (Ci-C4) alkyl, (C3-C6) - Cycloalkylcarbonyloxy- (Ci-C4) alkyl, arylsulfonyloxy (Ci-C4) alkyl, (Ci-C4) - alkylsulfonyloxy (Ci-C4) alkyl, Hydrothio- (Ci-C4) alkyl, (Ci-C4) alkylthio (Ci-C4) alkyl, (Ci C 4) -Haloalkylthio- (Ci-C 4) alkyl, aryl (Ci-C 4) alkylthio (Ci-C 4) alkyl, (C 3 -C 6) cycloalkylthio (Ci-C 4 ) alkyl, arylthio (Ci-C 4) alkyl,

(Ci-C 4 )-Alkylsulfinyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylsulfonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Haloalkylsulfinyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkylsulfonyl-(Ci-C 4 )-alkyl, Aryl- (Ci-C 4 )-alkylsulfinyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkylsulfonyl-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkylsulfinyl-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkylsulfonyl-(Ci-C 4 )- alkyl, Aryl, Heteroaryl, Heterocyclyl, N-[(Ci-C 4 )-Alkyl]heterocyclyl, N-[(Ci-C 4 )- Alkoxycarbonyl]heterocyclyl, N-[Aryl-(Ci-C 4 )-alkoxycarbonyl]heterocyclyl, N- (Arylcarbonyl)heterocyclyl, N-[(Ci-C 4 )-Alkylcarbonyl]heterocyclyl, N-[(Ci-C 4 )- Cycloalkylcarbonyl]heterocyclyl, Hydroxycarbonyl, (Ci-C 4 )-Alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkoxycarbonyl, Aryl- (Ci-C 4 )-alkoxycarbonyl, Heteroaryl-(Ci-C 4 )-alkoxycarbonyl, (Ci-C 4 )- Alkylaminocarbonyl, Aminocarbonyl, Bis-(Ci-C 4 )-alkylaminocarbonyl, (C3-C6)- Cycloalkylaminocarbonyl, Aryl-(Ci-C 4 )-alkylaminocarbonyl, (Ci-C4) alkylsulphinyl (Ci-C4) alkyl, (Ci-C4) alkylsulphonyl (Ci-C4) alkyl, (Ci-C4) - Haloalkylsulfinyl- (Ci-C 4 ) alkyl, (Ci-C4) -Haloalkylsulfonyl- (Ci-C4) alkyl, aryl (Ci-C4) alkylsulphinyl (Ci-C4) alkyl, aryl (Ci-C4) alkylsulfonyl (Ci-C 4) alkyl, (C 3 -C 6) -Cycloalkylsulfinyl- (Ci-C 4) alkyl, (C 3 -C 6) -Cycloalkylsulfonyl- (Ci-C 4) - alkyl, aryl, heteroaryl, heterocyclyl, N - [(Ci-C 4) -alkyl] heterocyclyl, N - [(Ci-C4) - alkoxycarbonyl] heterocyclyl, N- [aryl- (Ci-C 4) alkoxycarbonyl] heterocyclyl, N- (arylcarbonyl) heterocyclyl, N - [(Ci-C4) alkyl-carbonyl] heterocyclyl, N - [(Ci-C4) - cycloalkylcarbonyl] heterocyclyl, hydroxycarbonyl, (Ci-C4) alkoxycarbonyl, (C3-C6 ) cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C4) alkoxycarbonyl, aryl (Ci-C4) alkoxycarbonyl, heteroaryl (Ci-C4) -alkoxycarbonyl, (Ci-C4) - alkylaminocarbonyl, aminocarbonyl, bis (Ci-C4) alkylaminocarbonyl, (C3-C6) - cycloalkylaminocarbonyl, aryl (Ci-C4) alkylaminocarbonyl,

Heteroarylaminocarbonyl, Cyano-(Ci-C 4 )-alkylaminocarbonyl, (Ci-C 4 )- Haloalkylaminocarbonyl, (C2-C 4 )-Alkinyl-(Ci-C 4 )-alkylaminocarbonyl, Heteroarylaminocarbonyl, cyano (Ci-C4) alkylaminocarbonyl, (Ci-C4) - Haloalkylaminocarbonyl, (C2-C4) alkynyl (Ci-C4) alkylaminocarbonyl,

Hydroxycarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxycarbonyl-(CiC 4 )-alkyl, (C3-C6)- Cycloalkoxycarbonyl-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkoxycarbonyl- (Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkoxycarbonyl-(Ci-C 4 )-alkyl, Heteroaryl-(Ci-C 4 )- alkoxycarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylaminocarbonyl-(Ci-C 4 )-alkyl, Aminocarbonyl-(Ci-C 4 )-alkyl, Bis-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkylaminocarbonyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )- alkylaminocarbonyl-(Ci-C 4 )-alkyl, Heteroarylaminocarbonyl-(Ci-C 4 )-alkyl, Cyano-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Haloalkylaminocarbonyl-(Ci-C 4 )-alkyl, (C2-C 4 )-Alkinyl-(Ci-C 4 )- alkylaminocarbonyl-(Ci-C 4 )-alkyl, Amino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylamino- (Ci-C 4 )-alkyl, (C2-C 4 )-Alkenylamino-(Ci-C 4 )-alkyl, Arylamino-(Ci-C 4 )-alkyl, Bis- (Ci-C 4 )-alkylamino-(Ci-C 4 )-alkyl, Bis-(C3-C6)-cycloalkylamino-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkylamino-(Ci-C 4 )-alkyl, Tris-Aryl-(Ci-C 4 )-alkylamino-(Ci-C 4 )- alkyl, (C3-C 6 )-Cycloalkylamino-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C 4 )- alkylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylcarbonylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Cycloalkylcarbonylamino-(Ci-C 4 )- alkyl, Arylcarbonylamino-(Ci-C 4 )-alkyl, Heteroarylcarbonylamino-(Ci-C 4 )-alkyl, (Ci-C4)-Alkoxycarbonylamino-(Ci-C4)-alkyl, (C2-C4)-Alkenyloxycarbonylamino (Ci-C4)-alkyl, Aryl-(Ci-C4)-alkoxycarbonylamino-(Ci-C4)-alkyl, Aryl-(Ci-C 4 )- alkoxycarbonyl[N-(Ci-C4)-alkyl]amino-(Ci-C4)-alkyl, Heteroaryl-(Ci-C4)- alkoxycarbonylamino-(Ci-C4)-alkyl, (C3-C6)-Cycloalkyl-(Ci-C4)- alkoxycarbonylamino-(Ci-C4)-alkyl, (C3-C6)-Cycloalkoxycarbonylamino- (Ci-C4)-alkyl, Aminocarbonylamino-(Ci-C4)-alkyl, Arylsulfonylamino-(Ci-C4)- alkyl, Heteroarylsulfonylamino-(Ci-C4)-alkyl, (Ci-C4)-Alkylsulfonylamino- (Ci-C4)-alkyl, (C3-C6)-Cycloalkylsulfonylamino-(Ci-C4)-alkyl, Hydroxycarbonyl (Ci-C4) alkyl, (Ci-C4) alkoxycarbonyl (CiC 4) alkyl, (C3-C6) - Cycloalkoxycarbonyl- (Ci-C4) alkyl, (C3-C6) - cycloalkyl- (Ci-C4) alkoxycarbonyl (Ci-C4) alkyl, aryl (Ci-C4) alkoxycarbonyl (Ci-C4) alkyl, heteroaryl (Ci-C4) - alkoxycarbonyl - (Ci-C 4) alkyl, (Ci-C4) alkylaminocarbonyl (Ci-C 4) alkyl, aminocarbonyl (Ci-C 4) alkyl, bis (Ci-C4) -alkylaminocarbonyl- (Ci-C4) alkyl, (C3-C6) -Cycloalkylaminocarbonyl- (Ci-C4) alkyl, aryl (Ci-C4) - alkylaminocarbonyl (Ci-C4) alkyl, Heteroarylaminocarbonyl- (Ci C4) alkyl, cyano (Ci-C4) alkylaminocarbonyl (Ci-C4) alkyl, (Ci-C4) - Haloalkylaminocarbonyl- (Ci-C4) alkyl, (C2-C4 ) alkynyl (Ci-C4) - alkylaminocarbonyl (Ci-C4) alkyl, amino (Ci-C4) alkyl, (Ci-C4) -alkylamino (Ci-C4) alkyl , (C2-C 4) -Alkenylamino- (Ci-C 4) alkyl, arylamino (Ci-C 4) alkyl, bis (Ci-C 4) alkylamino (Ci-C 4) alkyl, bis (C3-C6) cycloalkylamino (Ci-C4) alkyl, aryl (Ci-C 4) alkylamino (C 4) alkyl, Tris-aryl (Ci-C4) - alkylamino (Ci-C 4) - alkyl, (C3-C6) cycloalkylamino (Ci-C 4) alkyl, (C 3 -C 6) cycloalkyl (Ci-C4) - alkylamino (C C4) alkyl, (Ci-C4) -Haloalkylamino- (Ci-C4) alkyl, (Ci-C4) - alkylcarbonylamino (Ci-C4) alkyl, (Ci-C4) - Cycloalkylcarbonylamino- (Ci-C4) - alkyl, arylcarbonylamino (Ci-C4) alkyl, Heteroarylcarbonylamino- (Ci-C4) alkyl, (Ci-C4) alkoxycarbonylamino (Ci-C4) alkyl, ( C2-C4) -Alkenyloxycarbonylamino (Ci-C4) alkyl, aryl (Ci-C4) alkoxycarbonylamino (Ci-C4) alkyl, aryl (Ci-C4) - alkoxycarbonyl [N- (Ci-C4) alkyl] amino (Ci-C4) alkyl, heteroaryl (Ci-C4) - alkoxycarbonylamino (Ci-C4) alkyl, (C3-C6) cycloalkyl (Ci-C4) - alkoxycarbonylamino (Ci C4) alkyl, (C3-C6) -Cycloalkoxycarbonylamino- (Ci-C4) alkyl, aminocarbonylamino (Ci-C4) alkyl, arylsulfonylamino (Ci-C4) - alkyl, Heteroarylsulfonylamino- (Ci-C4) alkyl , (Ci-C4) alkylsulfonylamino (Ci-C4) alkyl, (C3-C6) -Cycloalkylsulfonylamino- (Ci-C4) alkyl,

Aminoiminoamino-(Ci-C4)-alkyl, Arylsulfonylaminoiminoamino-(Ci-C4)-alkyl, (Ci-C4)-Alkylaminoiminoamino-(Ci-C4)-alkyl steht, für Wasserstoff, Halogen, (Ci-C 4 )-Alkyl, (Ci-C 4 )-Alkoxy, (C1-C4)- Aminoiminoamino- (Ci-C4) alkyl, Arylsulfonylaminoiminoamino- (Ci-C4) alkyl, (Ci-C4) -Alkylaminoiminoamino- (Ci-C4) alkyl, represents hydrogen, halogen, (Ci-C 4) -alkyl , (Ci-C4) alkoxy, (C1-C4) -

Alkoxycarbonyloxy, (C2-C4)-Alkenyl, (C2-C4)-Haloalkenyl, (C2-C4)-Alkenyl- (Ci-C 4 )-alkyl, (C2-C 4 )-Alkinyl, (C2-C4)-Alkinyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkyl, Bisaryl-(Ci-C 4 )-alkyl, Aryl-(Ci-C4)-alkoxyaryl-(Ci-C4)-alkyl, Aryloxyaryl-(Ci-C 4 ) alkyl, (Ci-C4)-Alkoxyaryl-(Ci-C4)-alkyl, Heteroaryl-(Ci-C4)-alkyl, Heterocyclyl- (Ci-C 4 )-alkyl, N-(Ci-C4)-Alkylheterocyclyl-(Ci-C4)-alkyl, N-[(Ci-C 4 )- Alkoxycarbonyl]heterocyclyl-(Ci-C4)-alkyl, N-(Aryl-(d-C4)- alkoxycarbonyl)heterocyclyl-(Ci-C4)-alkyl, N-(Arylcarbonyl)heterocyclyl- (Ci-C 4 )-alkyl, N-[(Ci-C4)-Alkylcarbonyl]heterocyclyl-(Ci-C4)-alkyl, N-[(C 3 -C 6 )- Cycloalkylcarbonyl]heterocyclyl-(Ci-C4)-alkyl, Cyano-(Ci-C4)-alkyl, (C1-C4)- Haloalkyl, (C 3 -C 6 )-Cycloalkyl, (C 3 -C 6 )-Halocycloalkyl, (C4-C 6 )-Cycloalkenyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C4)-alkyl, (C 3 -C 6 )-Cycloalkenyl-(Ci-C4)-alkyl, Hydroxy- (Ci-C 4 )-alkyl, (Ci-C4)-Alkoxy-(Ci-C4)-alkyl, (Ci-C4)-Haloalkoxy-(Ci-C4)-alkyl, Aryloxy-(Ci-C 4 )-alkyl, Aryl-(Ci-C4)-alkoxy-(Ci-C4)-alkyl, Heteroaryl-(Ci-C 4 )- alkoxy-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkoxy-(Ci-C4)-alkyl, (C 3 -C 6 )-Cycloalkyl- (Ci-C4)-alkoxy-(Ci-C4)-alkyl, (Ci-C4)-Alkylcarbonyloxy-(Ci-C4)-alkyl, Alkoxycarbonyloxy, (C2-C4) -alkenyl, (C2-C4) haloalkenyl, (C2-C4) -alkenyl (Ci-C4) alkyl, (C2-C4) alkynyl, (C2-C4) - alkynyl (Ci-C4) alkyl, aryl (Ci-C4) alkyl, bisaryl (Ci-C4) alkyl, aryl (Ci-C4) -alkoxyaryl- (Ci-C4) alkyl , Aryloxyaryl- (Ci-C4) alkyl, (Ci-C4) -Alkoxyaryl- (Ci-C4) alkyl, heteroaryl (Ci-C4) alkyl, heterocyclyl (Ci-C4) alkyl, N- (Ci-C4) -Alkylheterocyclyl- (Ci-C4) alkyl, N - [(Ci-C4) - alkoxycarbonyl] heterocyclyl (Ci-C4) alkyl, N- (aryl (d-C4) - alkoxycarbonyl ) heterocyclyl (Ci-C4) alkyl, N- (arylcarbonyl) heterocyclyl (Ci-C4) alkyl, N - [(Ci-C4) alkyl-carbonyl] heterocyclyl (Ci-C4) alkyl, N- [(C3-C6) - cycloalkylcarbonyl] heterocyclyl (Ci-C4) alkyl, cyano (Ci-C4) alkyl, (C1-C4) - haloalkyl, (C3-C6) -cycloalkyl, ( C 3 -C 6) halocycloalkyl, (C4-C6) cycloalkenyl, (C 3 -C 6) cycloalkyl (Ci-C4) alkyl, (C 3 -C 6) cycloalkenyl (Ci-C4 ) alkyl, hydroxy (Ci-C4) alkyl, (Ci-C4) alkoxy (Ci-C4) alkyl, (Ci-C4) haloalkoxy (Ci-C4) alkyl, aryloxy ( Ci-C4) alkyl, aryl (Ci-C4) alkoxy (Ci-C4) alkyl, heteroaryl (Ci-C4) - alkoxy (Ci-C4) alkyl, (C 3 - C6) cycloalkoxy (Ci-C4) alkyl, (C3-C6) cycloalkyl (Ci-C4) alkoxy (Ci-C4) alkyl, (Ci-C4) alkylcarbonyloxy (Ci C4) alkyl,

Arylcarbonyloxy-(Ci-C4)-alkyl, Heteroarylcarbonyloxy-(Ci-C4)-alkyl, (C3-C6)- Cycloalkylcarbonyloxy-(Ci-C4)-alkyl, Arylsulfonyloxy-(Ci-C4)-alkyl, (C1-C4)- Alkylsulfonyloxy-(Ci-C4)-alkyl, Hydrothio-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylthio- (Ci-C 4 )-alkyl, (Ci-C4)-Haloalkylthio-(Ci-C4)-alkyl, Aryl-(Ci-C 4 )-alkylthio- (Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkylthio-(Ci-C4)-alkyl, Arylthio-(Ci-C 4 )-alkyl, (Ci-C4)-Alkylsulfinyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylsulfonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Haloalkylsulfinyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkylsulfonyl-(Ci-C 4 )-alkyl, Aryl- (Ci-C 4 )-alkylsulfinyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkylsulfonyl-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkylsulfinyl-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkylsulfonyl-(Ci-C 4 )- alkyl, Aryl, Heteroaryl, Heterocyclyl, N-[(Ci-C 4 )-Alkyl]heterocyclyl, N-[(Ci-C 4 )- Alkoxycarbonyl]heterocyclyl, N-[Aryl-(Ci-C 4 )-alkoxycarbonyl]heterocyclyl, N- (Arylcarbonyl)heterocyclyl, N-[(Ci-C 4 )-Alkylcarbonyl]heterocyclyl, N-[(Ci-C 4 )- Cycloalkylcarbonyl]heterocyclyl, Hydroxycarbonyl, (Ci-C 4 )-Alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkoxycarbonyl, Aryl- (Ci-C 4 )-alkoxycarbonyl, Heteroaryl-(Ci-C 4 )-alkoxycarbonyl, (Ci-C 4 )- Alkylaminocarbonyl, Aminocarbonyl, Bis-(Ci-C 4 )-alkylaminocarbonyl, (C3-C6)- Cycloalkylaminocarbonyl, Aryl-(Ci-C 4 )-alkylaminocarbonyl, Arylcarbonyloxy (Ci-C4) alkyl, Heteroarylcarbonyloxy- (Ci-C4) alkyl, (C3-C6) - Cycloalkylcarbonyloxy- (Ci-C4) alkyl, arylsulfonyloxy (Ci-C4) alkyl, (C1-C4 ) - alkylsulfonyloxy (Ci-C4) alkyl, Hydrothio- (Ci-C4) alkyl, (Ci-C4) alkylthio (Ci-C4) alkyl, (Ci-C4) -Haloalkylthio- ( Ci-C4) alkyl, aryl (Ci-C4) alkylthio (Ci-C4) alkyl, (C3-C6) cycloalkylthio (Ci-C4) alkyl, arylthio (Ci C 4) alkyl, (Ci-C4) alkylsulphinyl (Ci-C4) alkyl, (Ci-C4) alkylsulphonyl (Ci-C4) alkyl, (Ci-C4) - Haloalkylsulfinyl- (Ci-C4) alkyl, (Ci-C4) -Haloalkylsulfonyl- (Ci-C4) alkyl, aryl (Ci-C4) alkylsulphinyl (Ci-C4) alkyl, aryl ( Ci-C 4) alkylsulfonyl (Ci-C 4) alkyl, (C 3 -C 6) -Cycloalkylsulfinyl- (Ci-C 4) alkyl, (C 3 -C 6) -Cycloalkylsulfonyl- (Ci-C 4) - alkyl, aryl, heteroaryl, heterocyclyl, N - [(Ci-C 4) -alkyl] heterocyclyl, N - [(Ci-C4) - alkoxycarbonyl] heterocyclyl, N- [aryl- (Ci-C 4) alkoxycarbonyl] heterocyclyl, N- (arylcarbonyl) heterocyclyl, N - [(Ci-C4) alkyl-carbonyl] heterocyclyl, N - [(Ci-C4) - cycloalkylcarbonyl] heterocyclyl, hydroxycarbonyl, (Ci-C4) alkoxycarbonyl , (C3-C6) cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C4) alkoxycarbonyl, aryl (Ci-C4) alkoxycarbonyl, heteroaryl (Ci-C4) -alkoxycarbonyl, (C C4) - alkylaminocarbonyl, aminocarbonyl, bis (Ci-C4) alkylaminocarbonyl, (C3-C6) - cycloalkylaminocarbonyl, aryl (Ci-C4) alkylaminocarbonyl,

Heteroarylaminocarbonyl, Cyano-(Ci-C 4 )-alkylaminocarbonyl, (Ci-C 4 )- Haloalkylaminocarbonyl, (C2-C 4 )-Alkinyl-(Ci-C 4 )-alkylaminocarbonyl, Heteroarylaminocarbonyl, cyano (Ci-C4) alkylaminocarbonyl, (Ci-C4) - Haloalkylaminocarbonyl, (C2-C4) alkynyl (Ci-C4) alkylaminocarbonyl,

Hydroxycarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxycarbonyl-(Ci-C 4 )-alkyl, (C3-C6)- Cycloalkoxycarbonyl-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkoxycarbonyl- (Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkoxycarbonyl-(Ci-C 4 )-alkyl, Heteroaryl-(Ci-C 4 )- alkoxycarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylaminocarbonyl-(Ci-C 4 )-alkyl, Aminocarbonyl-(Ci-C 4 )-alkyl, Bis-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkylaminocarbonyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )- alkylaminocarbonyl-(Ci-C 4 )-alkyl, Heteroarylaminocarbonyl-(Ci-C 4 )-alkyl, Cyano-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Haloalkylaminocarbonyl-(Ci-C 4 )-alkyl, (C2-C 4 )-Alkinyl-(Ci-C 4 )- alkylaminocarbonyl-(Ci-C 4 )-alkyl, Amino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylamino- (Ci-C 4 )-alkyl, (C2-C 4 )-Alkenylamino-(Ci-C 4 )-alkyl, Arylamino-(Ci-C 4 )-alkyl, Bis- (Ci-C 4 )-alkylamino-(Ci-C 4 )-alkyl, Bis-(C3-C6)-cycloalkylamino-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkylamino-(Ci-C 4 )-alkyl, Tris-Aryl-(Ci-C 4 )-alkylamino-(Ci-C 4 )- alkyl, (C3-C 6 )-Cycloalkylamino-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C 4 )- alkylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylcarbonylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Cycloalkylcarbonylamino-(Ci-C 4 )- alkyl, Arylcarbonylamino-(Ci-C 4 )-alkyl, Heteroarylcarbonylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxycarbonylamino-(Ci-C 4 )-alkyl, (C2-C 4 )-Alkenyloxycarbonylamino- (Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkoxycarbonylamino-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )- alkoxycarbonyl[N-(Ci-C 4 )-alkyl]amino-(Ci-C 4 )-alkyl, Heteroaryl-(Ci-C 4 )- alkoxycarbonylamino-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )- alkoxycarbonylamino-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkoxycarbonylamino- (Ci-C 4 )-alkyl, Aminocarbonylamino-(Ci-C 4 )-alkyl, Arylsulfonylamino-(Ci-C 4 )- alkyl, Heteroarylsulfonylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylsulfonylamino- (Ci-C 4 )-alkyl, (C3-C6)-Cycloalkylsulfonylamino-(Ci-C 4 )-alkyl, Hydroxycarbonyl (Ci-C4) alkyl, (Ci-C4) alkoxycarbonyl (Ci-C4) alkyl, (C3-C6) - Cycloalkoxycarbonyl- (Ci-C4) alkyl, (C3-C6 ) cycloalkyl- (Ci-C4) alkoxycarbonyl (Ci-C4) alkyl, aryl (Ci-C4) alkoxycarbonyl (Ci-C4) alkyl, heteroaryl (Ci-C4) - alkoxycarbonyl (Ci-C4) alkyl, (Ci-C4) alkylaminocarbonyl (Ci-C4) alkyl, aminocarbonyl (Ci-C4) alkyl, bis (Ci-C4) - alkylaminocarbonyl (Ci-C4) alkyl, (C3-C6) -Cycloalkylaminocarbonyl- (Ci-C4) alkyl, aryl (Ci-C4) - alkylaminocarbonyl (Ci-C4) alkyl, Heteroarylaminocarbonyl- (Ci-C4) alkyl, cyano (Ci-C4) alkylaminocarbonyl (Ci-C4) alkyl, (Ci-C4) - Haloalkylaminocarbonyl- (Ci-C4) alkyl, (C2 C4) alkynyl (Ci-C4) - alkylaminocarbonyl (Ci-C4) alkyl, amino (Ci-C4) alkyl, (Ci-C4) -alkylamino (Ci-C4) alkyl, (C2-C 4) -Alkenylamino- (Ci-C 4) alkyl, arylamino (Ci-C 4) alkyl, bis (Ci-C 4) alkylamino (Ci-C 4) - alkyl, bis (C3-C6) cycloalkylamino (Ci-C4) alkyl, aryl (Ci-C 4) alkylamino (C 4) alkyl, Tris-aryl (Ci-C 4 ) alkylamino (Ci-C 4) - alkyl, (C3-C6) cycloalkylamino (Ci-C 4) alkyl, (C 3 -C 6) cycloalkyl (Ci-C4) - alkylamino (Ci-C4) alkyl, (Ci-C4) -Haloalkylamino- (Ci-C4) alkyl, (Ci-C4) - alkylcarbonylamino (Ci-C4) alkyl, (Ci-C 4 ) -Cycloalkylcarbonylamino- (Ci-C4) - alkyl, arylcarbonylamino (Ci-C4) alkyl, Heteroarylcarbonylamino- (Ci-C4) alkyl, (Ci-C4) alkoxycarbonylamino (Ci-C4) alkyl, (C2-C4) -Alkenyloxycarbonylamino- (Ci-C4) alkyl, aryl (Ci-C4) alkoxycarbonylamino (Ci-C4) alkyl, aryl (Ci-C4) - alkoxycarbonyl [N- (Ci-C4) alkyl] amino (Ci-C4) alkyl, heteroaryl (Ci-C4) - alkoxycarbonylamino (Ci-C4) alkyl, (C3-C6) - cycloalkyl- (Ci-C4) - alkoxycarbonylamino (Ci-C4) alkyl, (C3-C6) -Cycloalkoxycarbonylamino- (Ci-C4) alkyl, aminocarbonylamino (Ci-C4) alkyl, arylsulfonylamino (Ci-C4) - alkyl, Heteroarylsulfonylamino- (Ci-C4) alkyl, (Ci-C4) alkylsulfonylamino (Ci-C4) alkyl, (C3-C6) -Cycloalkylsulfonylamino- (C 4) alkyl,

Aminoiminoamino-(Ci-C 4 )-alkyl, Arylsulfonylaminoiminoamino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylaminoiminoamino-(Ci-C 4 )-alkyl steht, Aminoiminoamino- (Ci-C 4) alkyl, Arylsulfonylaminoiminoamino- (Ci-C 4) alkyl, (Ci-C 4) -Alkylaminoiminoamino- (Ci-C 4) -alkyl,

R 6 und R 8 unabhängig voneinander für H, (Ci-C 4 )-Alkyl, (C 2 -C 4 )-Alkenyl-(Ci-C 4 )- alkyl, (C 2 -C 4 )-Alkinyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkyl, Heterocyclyl, Heterocyclyl-(Ci-C 4 )-alkyl, Amino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylthio-(Ci-C 4 )- alkyl, (Ci-C 4 )-Haloalkyl, (Ci-C 4 )-Alkylamino-(Ci-C 4 )-alkyl, Bis-(Ci-C 4 )- alkylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylcarbonylamino-(Ci-C 4 )-alkyl, (C3-C6)- Cycloalkylcarbonylamino-(Ci-C 4 )-alkyl, Arylcarbonylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxycarbonylamino-(Ci-C6)-alkyl, Aryl-(Ci-C 4 )-alkoxycarbonylamino (Ci-C 4 )-alkyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkoxycarbonylamino-(Ci-C 4 )-alkyl, Aminocarbonylamino-(Ci-C 4 )-alkyl, Aminoiminoamino-(Ci-C 4 )-alkyl, R 6 and R 8 independently represent H, (Ci-C 4) -alkyl, (C 2 -C 4) alkenyl, (Ci-C 4) - alkyl, (C 2 -C 4) alkynyl (C -C 4) alkyl, aryl (Ci-C 4) alkyl, (C 3 -C 6) -cycloalkyl, (C3-C6) cycloalkyl (Ci-C 4) alkyl, heterocyclyl, heterocyclyl ( Ci-C 4) alkyl, amino (Ci-C 4) alkyl, (Ci-C 4) alkoxy (Ci-C 4) alkyl, (Ci-C 4) alkylthio (Ci-C 4) - alkyl, (Ci-C4) -haloalkyl, (Ci-C4) -alkylamino (Ci-C4) alkyl, bis (Ci-C4) - alkyl amino (Ci-C4) - alkyl, (Ci-C4) -alkylcarbonylamino- (Ci-C4) alkyl, (C3-C6) - Cycloalkylcarbonylamino- (Ci-C4) alkyl, arylcarbonylamino (Ci-C4) alkyl, (Ci -C 4) alkoxycarbonylamino (Ci-C6) alkyl, aryl (Ci-C4) alkoxycarbonylamino (Ci-C4) alkyl, (C3-C6) cycloalkyl (Ci-C4) alkoxycarbonylamino - (Ci-C 4) alkyl, aminocarbonylamino (Ci-C 4) alkyl, Aminoiminoamino- (Ci-C 4) alkyl,

Arylsulfonylaminoiminoamino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylaminoiminoamino- (Ci-C 4 )-alkyl stehen, Arylsulfonylaminoiminoamino- (Ci-C4) alkyl, (Ci-C4) -Alkylaminoiminoamino- (Ci-C4) alkyl,

R 41 für H, (Ci-C 4 )-Alkyl, (C 2 -C 4 )-Alkenyl-(Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkinyl, (Ci-C 4 )- Alkylcarbonyl, (C3-C6)-Cycloalkylcarbonyl, Aryicarbonyi, Heteroarylcarbonyl, (Ci-C 4 )-Alkoxycarbonyl, Aryl-(Ci-C 4 )-alkoxycarbonyl, (C3-C6)- Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkoxycarbonyl, (Ci-C 4 )- Alkylsulfonyl, (C3-C6)-Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C 4 )- Alkoxycarbonylcarbonyl, Aryl-(Ci-C 4 )-alkoxycarbonylcarbonyl, (Ci-C 4 )- Alkylaminothiocarbonyl, (Ci-C 4 )-Alkylaminocarbonyl, Aryl-(Ci-C 4 )-alkyl, Hetaroaryl-(Ci-C 4 )-alkyl, Cyano-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, (C 3 -C 6 )- Cycloalkyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, (Ci-C4)-Haloalkoxy-(Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkinyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkoxycarbonyl-(Ci-C 4 )-alkyl, Aminocarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylaminocarbonyl-(Ci-C 4 )-alkyl, Bis-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl steht, R 41 is H, (Ci-C 4) -alkyl, (C 2 -C 4) alkenyl, (Ci-C 4) alkyl, (C 2 -C 4) alkynyl, (Ci-C 4) - alkylcarbonyl, (C3-C6) cycloalkylcarbonyl, Aryicarbonyi, heteroarylcarbonyl, (Ci-C4) alkoxycarbonyl, aryl (Ci-C4) -alkoxycarbonyl, (C3-C6) - cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C4) -alkoxycarbonyl, (Ci-C4) - alkylsulfonyl, (C3-C6) cycloalkylsulfonyl, arylsulphonyl, (Ci-C4) - alkoxycarbonylcarbonyl, aryl (Ci-C4) -alkoxycarbonylcarbonyl, (Ci C4) - alkylaminothiocarbonyl, (Ci-C4) alkylaminocarbonyl, aryl (Ci-C4) alkyl, Hetaroaryl- (Ci-C4) alkyl, cyano (Ci-C4) alkyl, ( Ci-C 4) -haloalkyl, (C 3 -C 6) - cycloalkyl, (C 3 -C 6) cycloalkyl (Ci-C 4) alkyl, (Ci-C 4) alkoxy (Ci-C 4) alkyl, (Ci-C4) haloalkoxy (Ci-C 4) alkyl, (C 2 -C 4) alkynyl (Ci-C 4) alkyl, (Ci-C4) - alkoxycarbonyl- (Ci-C 4) alkyl, aminocarbonyl (Ci-C 4) alkyl, (Ci-C4) - alkylaminocarbonyl (Ci-C 4) alkyl, bis (Ci-C4) -alkylaminocarbonyl- ( Ci-C 4) -alkyl,

im Falle der Gruppierung Q-21 ausschließlich für H oder Methyl steht, in the case of the group Q-21 is available exclusively for H or methyl,

R 42 für (C 2 -C 4 )-Alkyl, (C 2 -C 4 )-Alkenyl-(Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkinyl, (Ci-C 4 )- R 42 is (C 2 -C 4) alkyl, (C 2 -C 4) alkenyl, (Ci-C 4) alkyl, (C 2 -C 4) alkynyl, (Ci-C 4) -

Alkylcarbonyl, (C3-C6)-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl, (Ci-C 4 )-Alkoxycarbonyl, Aryl-(Ci-C 4 )-alkoxycarbonyl, (C3-C6)- Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkoxycarbonyl, (Ci-C 4 )- Alkylsulfonyl, (C3-C6)-Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C 4 )- Alkoxycarbonylcarbonyl, Aryl-(Ci-C 4 )-alkoxycarbonylcarbonyl, (Ci-C 4 )- Alkylaminothiocarbonyl, (Ci-C 4 )-Alkylaminocarbonyl, Aryl-(Ci-C 4 )-alkyl, Hetaroaryl-(Ci-C 4 )-alkyl, Cyano-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, (C 3 -C 6 )- Cycloalkyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, Alkylcarbonyl, (C3-C6) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl, (Ci-C4) alkoxycarbonyl, aryl (Ci-C4) -alkoxycarbonyl, (C3-C6) - cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C4) -alkoxycarbonyl, (Ci-C4) - alkylsulfonyl, (C3-C6) cycloalkylsulfonyl, arylsulphonyl, (Ci-C4) - alkoxycarbonylcarbonyl, aryl (Ci-C4) -alkoxycarbonylcarbonyl, (Ci C4) - alkylaminothiocarbonyl, (Ci-C4) alkylaminocarbonyl, aryl (Ci-C4) alkyl, Hetaroaryl- (Ci-C4) alkyl, cyano (Ci-C4) alkyl, ( Ci-C 4) -haloalkyl, (C 3 -C 6) - cycloalkyl, (C 3 -C 6) cycloalkyl (Ci-C 4) alkyl, (Ci-C 4) alkoxy (Ci-C 4) alkyl,

(Ci-C 4 )-Haloalkoxy-(Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkinyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkoxycarbonyl-(Ci-C 4 )-alkyl, Aminocarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylaminocarbonyl-(Ci-C 4 )-alkyl, Bis-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl steht, (Ci-C4) haloalkoxy (Ci-C4) alkyl, (C2-C4) alkynyl (Ci-C4) alkyl, (Ci-C4) - alkoxycarbonyl (C 4) alkyl, aminocarbonyl (Ci-C 4) alkyl, (Ci-C4) - alkylaminocarbonyl (Ci-C 4) alkyl, bis (Ci-C4) alkylaminocarbonyl (Ci-C 4 ) -alkyl,

R 43 für H oder Methyl steht, R 43 is H or methyl,

R 44 für Wasserstoff, (Ci-C 4 )-Alkyl, (C 2 -C 4 )-Alkenyl-(Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkinyl, (Ci-C 4 )-Alkylcarbonyl, (C3-C6)-Cycloalkylcarbonyl, Arylcarbonyl, R 44 is hydrogen, (Ci-C 4) -alkyl, (C 2 -C 4) alkenyl (Ci-C 4) alkyl, (C 2 -C 4) alkynyl, (Ci-C 4) - alkylcarbonyl, (C3-C6) cycloalkylcarbonyl, arylcarbonyl,

Heteroarylcarbonyl, (Ci-C 4 )-Alkoxycarbonyl, Aryl-(Ci-C 4 )-alkoxycarbonyl, Heteroarylcarbonyl, (Ci-C4) alkoxycarbonyl, aryl (Ci-C4) alkoxycarbonyl,

(C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkoxycarbonyl, (C3-C6) cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C4) alkoxycarbonyl,

(Ci-C 4 )-Alkylsulfonyl, (C 3 -C 6 )-Cycloalkylsulfonyl, Arylsulfonyl, (Ci-C 4 )- Alkoxycarbonylcarbonyl, Aryl-(Ci-C 4 )-alkoxycarbonylcarbonyl, (Ci-C 4 )- Alkylaminothiocarbonyl, (Ci-C 4 )-Alkylaminocarbonyl, Aryl-(Ci-C 4 )-alkyl, Hetaroaryl-(Ci-C 4 )-alkyl, Cyano-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, (C 3 -C 6 )- Cycloalkyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, (Ci-C4) alkylsulphonyl, (C3-C6) cycloalkylsulfonyl, arylsulphonyl, (Ci-C4) - alkoxycarbonylcarbonyl, aryl (Ci-C4) -alkoxycarbonylcarbonyl, (Ci-C4) - alkylaminothiocarbonyl, (Ci-C4) alkylaminocarbonyl, aryl (Ci-C4) alkyl, Hetaroaryl- (Ci-C4) alkyl, cyano (Ci-C4) alkyl, (Ci-C4) -haloalkyl , (C 3 -C 6) - cycloalkyl, (C 3 -C 6) cycloalkyl (Ci-C 4) alkyl, (Ci-C 4) alkoxy (Ci-C 4) alkyl,

(Ci-C 4 )-Haloalkoxy-(Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkinyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkoxycarbonyl-(Ci-C 4 )-alkyl, Aminocarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylaminocarbonyl-(Ci-C 4 )-alkyl, Bis-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl steht, (Ci-C4) haloalkoxy (Ci-C4) alkyl, (C2-C4) alkynyl (Ci-C4) alkyl, (Ci-C4) - alkoxycarbonyl (C 4) alkyl, aminocarbonyl (Ci-C 4) alkyl, (Ci-C4) - alkylaminocarbonyl (Ci-C 4) alkyl, bis (Ci-C4) alkylaminocarbonyl (Ci-C 4 ) -alkyl,

R 51 und R 71 unabhängig voneinander für Wasserstoff und Methyl stehen, R 53 für Methyl steht, R 61 und R 81 unabhängig voneinander für Wasserstoff und Methyl stehen, R 63 für H, Methyl steht, R 51 and R 71 independently represent hydrogen and methyl, R 53 is methyl, R 61 and R 81 independently represent hydrogen and methyl, R 63 is H, methyl,

R 54 , R 64 , R 74 , R 84 unabhängig voneinander für Wasserstoff, Methyl stehen, wobei mindestens eine der Gruppen R 54 , R 64 , R 74 , R 84 für Methyl stehen muß, R 54, R 64, R 74, R 84 are independently hydrogen, methyl, where at least one of R 54, R 64, R 74, R 84 must be methyl,

V für Hydroxycarbonyl, (Ci-C 4 )-Alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C 4 )- alkoxycarbonyl, Aminocarbonyl, (Ci-C 4 )-Alkylaminocarbonyl, Bis-(Ci-C 4 )- alkylaminocarbonyl, (Ci-C 4 )-Alkyl[(Ci-C 4 )-Alkoxy]aminocarbonyl, (C3-C6)- V hydroxycarbonyl, (Ci-C4) alkoxycarbonyl, (C3-C6) cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C4) alkoxycarbonyl, aryloxycarbonyl, aryl (Ci-C4) - alkoxycarbonyl , aminocarbonyl, (Ci-C4) alkylaminocarbonyl, bis (Ci-C4) - alkylaminocarbonyl, (Ci-C4) alkyl [(Ci-C4) alkoxy] aminocarbonyl, (C3-C6) -

Cycloalkylaminocarbonyl, Aryl-(Ci-C 4 )-alkylaminocarbonyl, Heteroaryl-(Ci-C 4 )- alkylaminocarbonyl, Cyano-(Ci-C 4 )-alkylaminocarbonyl, (Ci-C 4 )- Haloalkylaminocarbonyl, (C2-C 4 )-Alkinyl-(Ci-C 4 )-alkylaminocarbonyl, (Ci-C 4 )- Alkoxycarbonyl-(Ci-C 4 )-alkylaminocarbonyl, Hydroxycarbonyl-(Ci-C 4 )- alkylaminocarbonyl, Aminocarbonyl-(Ci-C 4 )-alkylaminocarbonyl, (Ci-C 4 )- Cycloalkylaminocarbonyl, aryl (Ci-C4) alkylaminocarbonyl, heteroaryl (Ci-C4) - alkylaminocarbonyl, cyano (Ci-C4) alkylaminocarbonyl, (Ci-C4) - Haloalkylaminocarbonyl, (C2-C4) alkynyl (Ci-C4) alkylaminocarbonyl, (Ci-C4) - alkoxycarbonyl (Ci-C4) alkylaminocarbonyl, hydroxycarbonyl (Ci-C4) - alkylaminocarbonyl, aminocarbonyl (Ci-C4) - alkylaminocarbonyl, (Ci-C4) -

Alkylaminocarbonyl-(Ci-C 4 )-alkylaminocarbonyl, (C3-C6)- Cycloalkylaminocarbonyl-(Ci-C 4 )-alkylaminocarbonyl, (C3-C6)-Cycloalkyl- (Ci-C 4 )-alkylaminocarbonyl steht, m für 0, 1 , 2, 3, 4, 5 steht, p für 1 , 2, 3, 4 steht, für Cyano, Cyano-(Ci-C 4 )-alkyl, Hydroxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )- alkyl, Hydroxycarbonyl, (Ci-C 4 )-Alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkoxycarbonyl, Aryloxycarbonyl, Aryl-(Ci-C 4 )- alkoxycarbonyl, Aminocarbonyl, (Ci-C 4 )-Alkylaminocarbonyl, Bis-(Ci-C 4 )- alkylaminocarbonyl, (Ci-C 4 )-Alkyl[(Ci-C 4 )-Alkoxy]aminocarbonyl, (C3-C6)- Cycloalkylaminocarbonyl, Aryl-(Ci-C 4 )-alkylaminocarbonyl, Heteroaryl-(Ci-C 4 )- alkylaminocarbonyl, Cyano-(Ci-C 4 )-alkylaminocarbonyl, (Ci-C 4 )- Haloalkylaminocarbonyl, (C2-C 4 )-Alkinyl-(Ci-C 4 )-alkylaminocarbonyl, (Ci-C 4 )- Alkoxycarbonylaminocarbonyl, Aryl-(Ci-C 4 )-alkoxycarbonylaminocarbonyl, Hydroxycarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxycarbonyl-(CiC 4 )-alkyl, (C3-C6)- Cycloalkoxycarbonyl-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkoxycarbonyl- (Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylaminocarbonyl-(Ci-C 4 )-alkyl, Aminocarbonyl- (Ci-C 4 )-alkyl, Bis-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, (C 3 -C 6 )- Cycloalkylaminocarbonyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkylaminocarbonyl- (Ci-C 4 )-alkyl, Heteroaryl-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, Cyano- (Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkylaminocarbonyl- (Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkinyl-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, Alkylaminocarbonyl (Ci-C4) alkylaminocarbonyl, (C3-C6) - cycloalkylaminocarbonyl (Ci-C4) alkylaminocarbonyl, (C3-C6) cycloalkyl (Ci-C4) alkylaminocarbonyl, m is 0, 1, 2, 3, 4, 5, p is 1, 2, 3, 4, represents cyano, cyano (Ci-C 4) alkyl, hydroxy (Ci-C 4) alkyl, (Ci- C 4) alkoxy (Ci-C4) - alkyl, hydroxycarbonyl, (Ci-C4) alkoxycarbonyl, (C3-C6) cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C4) alkoxycarbonyl , aryloxycarbonyl, aryl (Ci-C4) - alkoxycarbonyl, aminocarbonyl, (Ci-C4) alkylaminocarbonyl, bis (Ci-C4) - alkylaminocarbonyl, (Ci-C4) alkyl [(C 4 ) -alkoxy] aminocarbonyl, (C3-C6) - cycloalkylaminocarbonyl, aryl (Ci-C4) alkylaminocarbonyl, heteroaryl (Ci-C4) - alkylaminocarbonyl, cyano (Ci-C4) alkylaminocarbonyl, (Ci C 4) - Haloalkylaminocarbonyl, (C2-C4) alkynyl (Ci-C4) alkylaminocarbonyl, (Ci-C4) - Alkoxycarbonylaminocarbonyl, aryl (Ci-C4) -alkoxycarbonylaminocarbonyl, hydroxycarbonyl (C 4) alkyl, (Ci-C4) alkoxycarbonyl (CiC 4) alkyl, (C3-C6) - Cycloalkoxycarbonyl- (Ci-C4) alkyl, (C3-C6) cycloalkyl (C 4) alkoxycarbonyl (Ci-C 4) alkyl, (Ci-C4) alkylaminocarbonyl (Ci-C 4) alkyl, aminocarbonyl (Ci-C 4) alkyl, bis (Ci-C 4 ) -alkylaminocarbonyl- (Ci-C4) alkyl, (C3-C6) - cycloalkylaminocarbonyl (Ci-C4) alkyl, aryl (Ci-C4) alkylaminocarbonyl (Ci-C4) - alkyl, heteroaryl (Ci-C4) alkylaminocarbonyl (Ci-C4) alkyl, cyano (Ci-C4) alkylaminocarbonyl (Ci-C4) alkyl, (Ci-C4) -Haloalkylaminocarbonyl - (Ci-C 4) alkyl, (C 2 -C 4) alkynyl (Ci-C 4) -alkylaminocarbonyl- (Ci-C 4) alkyl,

(C3-C 6 )-Cycloalkyl-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkoxycarbonylaminocarbonyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )- alkoxycarbonylaminocarbonyl-(Ci-C 4 )-alkyl, (C3-C6) cycloalkyl (Ci-C4) alkylaminocarbonyl (Ci-C4) alkyl, (Ci-C4) - Alkoxycarbonylaminocarbonyl- (Ci-C4) alkyl, aryl (Ci C 4) - alkoxycarbonylaminocarbonyl- (Ci-C 4) alkyl,

(Ci-C 4 )-Alkoxycarbonyl-(Ci-C 4 )-alkylaminocarbonyl, Hydroxycarbonyl-(Ci-C 4 )- alkylaminocarbonyl, Aminocarbonyl-(Ci-C 4 )-alkylaminocarbonyl, (Ci-C 4 )- Alkylaminocarbonyl-(Ci-C 4 )-alkylaminocarbonyl, (C3-C6)- Cycloalkylaminocarbonyl-(Ci-C 4 )-alkylaminocarbonyl, (C3-C6)-Cycloalkyl- (Ci-C 4 )-alkylaminocarbonyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkylaminocarbonyl- (Ci-C 4 )-alkyl, (C2-C 4 )-Alkenyloxycarbonyl, (C2-C 4 )-Alkenyloxycarbonyl-(Ci-C 4 )- alkyl, (C2-C 4 )-Alkenylaminocarbonyl, (C2-C 4 )-Alkenyl-(Ci-C 4 )- alkylaminocarbonyl, (C2-C 4 )-Alkenylaminocarbonyl-(Ci-C 4 )-alkyl, (C2-C 4 )- Alkenyl-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl steht. (Ci-C4) alkoxycarbonyl (Ci-C4) alkylaminocarbonyl, hydroxycarbonyl (Ci-C4) - alkylaminocarbonyl, aminocarbonyl (Ci-C4) alkylaminocarbonyl, (Ci-C4) - alkylaminocarbonyl ( Ci-C4) alkylaminocarbonyl, (C3-C6) - cycloalkylaminocarbonyl (Ci-C4) alkylaminocarbonyl, (C3-C6) cycloalkyl (Ci-C4) alkylaminocarbonyl, (C3-C6) cycloalkyl (Ci-C4) alkylaminocarbonyl (Ci-C4) alkyl, (C2-C4) alkenyloxycarbonyl, (C2-C4) -Alkenyloxycarbonyl- (Ci-C4) - alkyl, (C2-C4 ) -Alkenylaminocarbonyl, (C2-C4) -alkenyl (Ci-C4) - alkylaminocarbonyl, (C2-C4) -Alkenylaminocarbonyl- (Ci-C4) alkyl, (C2-C4) - alkenyl ( Ci-C4) alkylaminocarbonyl (Ci-C4) alkyl. und Q weiterhin für eine der in der folgenden Tabelle spezifisch benannten Gruppierungen Q-1 .1 bis Q-24.15 steht Q and continue for a specifically designated in the following table groups Q 1 .1 stands to Q 24.15

Figure imgf000044_0001
Figure imgf000045_0001
Figure imgf000045_0002
Figure imgf000045_0004
Figure imgf000045_0003

Figure imgf000046_0001
Figure imgf000046_0002
Figure imgf000046_0003

Figure imgf000047_0001
Figure imgf000047_0002
Figure imgf000047_0003
Q-1.139 Q-1.140 Q-1.141 Q-1.142 Q-1.143 Q-1.144 Q 1139 Q 1140 Q 1141 Q 1142 Q 1143 Q 1144
Figure imgf000048_0001

Q-1.157 Q-1.158 Q-1.159 Q-1.160 Q-1.161 Q-1.162 Q 1157 Q 1158 Q 1159 Q 1160 Q 1161 Q 1162

Figure imgf000048_0002
Figure imgf000049_0001

Figure imgf000049_0003

Figure imgf000049_0002

Figure imgf000050_0002

Figure imgf000050_0003

Figure imgf000050_0001
Figure imgf000051_0001

Figure imgf000051_0003

Figure imgf000051_0004

V ^ N V ^ N

H H

HH HH

Q-20.7 Q-20.8 Q-20.9 Q-20.10 Q-20.11 Q-20.12 Q 20.7 Q 20.8 Q 20.9 Q 20:10 20:11 Q Q 20:12

- ' \ /\ / OH - ' \ /\ / OH - '\ / \ / OH OH

HIHIH ii H II \ ' N Π ' N kf 0 0 0 0 0 Hihih II H II \ 'N Π' N kf 0 0 0 0 0

Q-21.1 Q-21.2 Q-21.3 Q-21.4 Q-21.5 Q-21.6 Q 21.1 Q 21.2 Q 21.3 Q 21.4 Q 21.5 Q 21.6

Figure imgf000051_0002
Figure imgf000052_0001

oooooo oooooo

OH OH

Q-22.1 Q-22.2 Q-22.3 Q-22.4 Q-22.5 Q-22.6 Q 22.1 Q 22.2 Q 22.3 Q 22.4 Q 22.5 Q 22.6

Figure imgf000052_0002
Ganz besonders bevorzugt ist die erfindungsgemäße Verwendung von Verbindungen der allgemeinen Formel (I), worin Most preferably, the inventive use of compounds of general formula (I) wherein

Figure imgf000053_0001
zur Toleranzerhöhung gegenüber abiotischem Stress in Pflanzen, worin Q für die Gruppierungen to increase tolerance to abiotic stress in plants, where Q represents the groups

Figure imgf000053_0002

Q-1 Q-20 Q-21 Q-1 Q-20 Q-21

Figure imgf000053_0003

Q-22 Q-23 Q-24 steht, und wobei die Reste R 4 bis R 8 , und R 41 bis R 84 sowie Y, V, m und p jeweils die Bedeutung gemäß der nachstehenden Definitionen haben und wobei der Pfeil für eine Bindung zum Schwefelatom der S0 2 -Gruppe steht; Q-22 Q-23 Q-24 is, and where the radicals R 4 to R 8 and R 41 to R 84 and Y, V, m and p are each as defined in accordance with the following definitions and where the arrow for a bond stands for sulfur atom of the S0 2 group; A 1 , A 2 , A 3 gleich oder verschieden sind und unabhängig voneinander für N A 1, A 2, A 3 are identical or different and are each independently N

(Stickstoff) oder die Gruppierung CW stehen, wobei jedoch in keinem Fall mehr als zwei N-Atome benachbart sind, und wobei W in der Gruppierung C- Wjeweils gleiche oder verschiedene Bedeutungen gemäß der (Nitrogen) or the group CW are, but in no case more than two N atoms are adjacent, and wherein W in the group C- Wjeweils identical or different meanings in accordance with the

nachstehenden Definition hat, W jeweils für Wasserstoff, Nitro, Amino, Cyano, Fluor, Chlor, Brom, lod, (Ci-C 4 )- Alkyl, (C 2 -C 4 )-Alkenyl, Aryl, Aryl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkoxy, Heteroaryl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, (Ci-C 4 )-Alkoxy, (Ci-C 4 )- Haloalkoxy, Aryloxy, (C3-C6)-Cycloalkyloxy, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkoxy, (Ci-C 4 )-Alkoxycarbonyl, Hydroxycarbonyl, Aminocarbonyl, (Ci-C 4 )- Alkylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Cyano-(Ci-C 4 )- alkylaminocarbonyl, (Ci-C 4 )-Alkylamino, (Ci-C 4 )-Alkylthio, (Ci-C 4 )- Haloalkylthio, Bis-(Ci-C 4 )-alkylamino, (C3-C6)-Cycloalkylamino, (Ci-C 4 )- Alkylcarbonylamino, (C3-C6)-Cycloalkylcarbonylamino, (Ci-C 4 )- Haloalkylcarbonylamino, (Ci-C 4 )-Alkoxycarbonylamino, (Ci-C 4 )- Alkylaminocarbonylamino, Bis-[(Ci-C 4 )-Alkyl]-aminocarbonyl-amino, Aryl- (Ci-C 4 )-alkylcarbonylamino, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkylcarbonylamino, Heteroarylcarbonylamino, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkylcarbonylamino, Definition below, has W are each hydrogen, nitro, amino, cyano, fluorine, chlorine, bromine, iodine, (Ci-C 4) - alkyl, (C 2 -C 4) alkenyl, aryl, aryl (Ci-C 4) alkyl, aryl (Ci-C4) alkoxy, heteroaryl, (Ci-C4) alkoxy (Ci-C4) alkyl, (Ci-C4) -haloalkyl, (C 4 ) -alkoxy, (Ci-C4) - haloalkoxy, aryloxy, (C3-C6) -cycloalkyloxy, (C3-C6) cycloalkyl (Ci-C4) -alkoxy, (Ci-C4) alkoxycarbonyl, hydroxycarbonyl , aminocarbonyl, (Ci-C4) - alkylaminocarbonyl, (C3-C6) cycloalkylaminocarbonyl, cyano (Ci-C4) - alkylaminocarbonyl, (Ci-C4) alkylamino, (Ci-C4) -alkylthio, ( Ci-C4) - haloalkylthio, bis (Ci-C4) alkylamino, (C3-C6) cycloalkylamino, (Ci-C4) - alkylcarbonylamino, (C3-C6) -Cycloalkylcarbonylamino, (Ci-C4) - Haloalkylcarbonylamino, (Ci-C4) alkoxycarbonylamino, (Ci-C4) - alkylaminocarbonylamino, bis - [(Ci-C4) alkyl] aminocarbonyl-amino, aryl (Ci-C 4) alkylcarbonylamino, ( C3-C6) cycloalkyl (Ci-C4) alkylcarbonylamino, heteroarylcarbonylamino, (Ci-C4) alkoxy (Ci-C 4) alkylcarbonylamino,

Hydroxy-(Ci-C 4 )-alkylcarbonylamino, (Ci-C 4 )-Alkoxycarbonyl-(Ci-C 4 )-alkyl steht, Hydroxy (Ci-C 4) alkylcarbonylamino, (Ci-C4) alkoxycarbonyl (Ci-C4) alkyl,

R 1 für H, Nitro, Amino, Cyano, Fluor, Chlor, Brom, lod, (Ci-C 4 )-Alkyl, (C 2 -C 4 )- Alkenyl, Aryl, Aryl-(Ci-C 4 )-alkyl, Heteroaryl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, R 1 is H, nitro, amino, cyano, fluorine, chlorine, bromine, iodine, (Ci-C 4) -alkyl, (C 2 -C 4) - alkenyl, aryl, aryl (Ci-C 4) -alkyl , heteroaryl, (Ci-C 4) alkoxy (Ci-C 4) alkyl,

(Ci-C 4 )-Haloalkyl, (Ci-C 4 )-Alkoxy, (Ci-C 4 )-Haloalkoxy, (Ci-C 4 )-Alkylthio, (Ci-C4) -haloalkyl, (Ci-C4) -alkoxy, (Ci-C4) haloalkoxy, (Ci-C4) -alkylthio,

(Ci-C 4 )-Haloalkylthio, (Ci-C 4 )-Alkoxycarbonyl, Hydroxycarbonyl, (Ci-C 4) haloalkylthio, (Ci-C4) alkoxycarbonyl, hydroxycarbonyl,

Aminocarbonyl, (Ci-C 4 )-Alkylaminocarbonyl, (Ci-C 4 )-Alkylamino, Bis-(Ci-C 4 )- alkylamino, (C3-C6)-Cycloalkylamino, (Ci-C 4 )-Alkylcarbonylamino, (C3-C6)- Cycloalkylcarbonylamino, (Ci-C 4 )-Haloalkylcarbonylamino, (Ci-C 4 )- Alkoxycarbonylamino, [(Ci-C 4 )-Alkyl-]aminocarbonyl-amino, Amino-(Ci-C 4 )- alkyl, Amino-(C2-C 4 )-alkenyl, (C2-C 4 )-Alkenylamino, (C2-C 4 )-Alkenylimino steht, Aminocarbonyl, (Ci-C4) alkylaminocarbonyl, (Ci-C4) alkylamino, bis (C 4) - alkylamino, (C3-C6) cycloalkylamino, (Ci-C 4) alkylcarbonylamino, (C3 C6) - cycloalkylcarbonylamino, (Ci-C4) -Haloalkylcarbonylamino, (Ci-C4) - alkoxycarbonylamino, [(Ci-C4) -alkyl] aminocarbonyl-amino, amino (Ci-C4) - alkyl, amino (C2-C4) -alkenyl, (C2-C4) alkenylamino, (C2-C4) -Alkenylimino stands,

R 2 für H, Nitro, Amino, Cyano, Fluor, Chlor, Brom, lod, (Ci-C 4 )-Alkyl, (C 2 -C 4 )- Alkenyl, Aryl, Aryl-(Ci-C 4 )-alkyl, Heteroaryl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, R 2 is H, nitro, amino, cyano, fluorine, chlorine, bromine, iodine, (Ci-C 4) -alkyl, (C 2 -C 4) - alkenyl, aryl, aryl (Ci-C 4) -alkyl , heteroaryl, (Ci-C 4) alkoxy (Ci-C 4) alkyl,

(Ci-C 4 )-Haloalkyl, (Ci-C 4 )-Alkoxy, (Ci-C 4 )-Haloalkoxy, (Ci-C 4 )-Alkylthio, (Ci-C4) -haloalkyl, (Ci-C4) -alkoxy, (Ci-C4) haloalkoxy, (Ci-C4) -alkylthio,

(Ci-C 4 )-Haloalkylthio, (Ci-C 4 )-Alkoxycarbonyl, Hydroxycarbonyl, (Ci-C 4) haloalkylthio, (Ci-C4) alkoxycarbonyl, hydroxycarbonyl,

Aminocarbonyl, (Ci-C 4 )-Alkylaminocarbonyl, (Ci-C 4 )-Alkylamino, Bis-(Ci-C 4 )- alkylamino, (C3-C6)-Cycloalkylamino, (Ci-C 4 )-Alkylcarbonylamino, (C3-C6)- Cycloalkylcarbonylamino, (Ci-C 4 )-Haloalkylcarbonylamino, (Ci-C 4 )- Alkoxycarbonylamino, [(Ci-C 4 )-Alkyl-]-aminocarbonyl-amino, Amino-(Ci-C 4 )- alkyl, Amino-(C2-C 4 )-alkenyl, (C2-C 4 )-Alkenylamino, (C2-C 4 )-Alkenylimino steht, Aminocarbonyl, (Ci-C4) alkylaminocarbonyl, (Ci-C4) alkylamino, bis (C 4) - alkylamino, (C3-C6) cycloalkylamino, (Ci-C 4) alkylcarbonylamino, (C3 C6) - cycloalkylcarbonylamino, (Ci-C4) -Haloalkylcarbonylamino, (Ci-C4) - alkoxycarbonylamino, [(Ci-C4) alkyl -] - aminocarbonyl-amino, amino (Ci-C4) - alkyl , amino (C2-C4) -alkenyl, (C2-C4) alkenylamino, (C2-C4) -Alkenylimino stands,

R 1 und R 2 mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten, teilgesättigten oder vollständig ungesättigten, gegebenenfalls durch R 1 and R 2 with the atoms to which they are attached form a fully saturated, partially saturated or fully unsaturated, optionally substituted by

Heteroatome unterbrochenen und gegebenenfalls weiter durch W Heteroatoms and optionally further interrupted by W

substituierten 5 bis 7-gliedrigen Ring bilden, und wobei sie im Falle der Verbindungen der allgemeinen Formel (I) mit den Gruppierungen Q-21 und Q- 23 einen entsprechenden Ring bilden müssen. substituted 5 to 7-membered ring, and being (I) to form with the moieties Q-21 and Q 23, a corresponding ring in the case of compounds of the general formula.

R 1 und A 3 , wenn A 3 für eine Gruppe CW steht, mit den Atomen, an die sie gebunden sind, einen vollständig gesättigten, teilgesättigten oder vollständig R 1 and A 3, when A 3 is a group CW, with the atoms to which they are attached form a fully saturated, partially saturated or fully

ungesättigten, gegebenenfalls durch Heteroatome unterbrochenen und gegebenenfalls weiter substituierten 5 bis 7-gliedrigen Ring bilden, unsaturated, optionally interrupted by hetero atoms and optionally further substituted form 5 to 7-membered ring,

X für eine direkte Bindung oder für eine Gruppierung (CHR 3 ) n steht, und wobei R 3 in der Gruppierung (CHR 3 ) n jeweils gleiche oder verschiedene X represents a direct bond or a group (CHR 3) n and wherein R 3 in the group (CHR 3) n are identical or different

Bedeutungen gemäß der nachstehenden Definition hat, n für 0, 1 steht Meanings as defined below, has n is 0, 1 is

R 3 für H, (Ci-C 4 )-Alkyl, (Ci-C 4 )-Haloalkyl, (C 3 -C 6 )-Cycloalkyl, Aryl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl steht, R 3 is H, (Ci-C 4) alkyl, (Ci-C 4) -haloalkyl, (C 3 -C 6) cycloalkyl, aryl (Ci-C 4) alkyl, (Ci-C 4) alkoxy (Ci-C 4) -alkyl,

R 4 für H, (Ci-C 4 )-Alkyl, (C 2 -C 4 )-Alkenyl-(Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkinyl, (Ci-C 4 )- Alkylcarbonyl, (C3-C6)-Cycloalkylcarbonyl, Arylcarbonyl, Heteroarylcarbonyl, (Ci-C 4 )-Alkoxycarbonyl, Aryl-(Ci-C 4 )-alkoxycarbonyl, (Ci-C 4 )- Alkylaminocarbonyl, Aryl-(Ci-C 4 )-alkyl, Hetaroaryl-(Ci-C 4 )-alkyl, Cyano- (Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, (C 3 -C 6 )-Cycloalkyl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )- alkyl, (Ci-C4)-Haloalkoxy-(Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkinyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkoxycarbonyl-(Ci-C 4 )-alkyl steht, für Fluor, (C 2 -C 4 )-Alkyl, (Ci-C 4 )-Alkoxy, (Ci-C 4 )-Alkoxycarbonyloxy, (C 2 -C 4 )- Alkenyl, (C 2 -C 4 )-Haloalkenyl, (C 2 -C 4 )-Alkenyl-(Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkinyl, (C 2 -C 4 )-Alkinyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkyl, Bisaryl-(Ci-C 4 )-alkyl, Aryl- (Ci-C 4 )-alkoxyaryl-(Ci-C 4 )-alkyl, Aryloxyaryl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxyaryl- (Ci-C 4 )-alkyl, Heteroaryl-(Ci-C 4 )-alkyl, Heterocyclyl-(Ci-C 4 )-alkyl, N-(Ci-C 4 )- Alkylheterocyclyl-(Ci-C 4 )-alkyl, N-[(Ci-C 4 )-Alkoxycarbonyl]heterocyclyl- (Ci-C 4 )-alkyl, N-(Aryl-(Ci-C 4 )-alkoxycarbonyl)heterocyclyl-(Ci-C 4 )-alkyl, N- (Arylcarbonyl)heterocyclyl-(Ci-C 4 )-alkyl, N-[(Ci-C 4 )-Alkylcarbonyl]heterocyclyl (Ci-C 4 )-alkyl, N-[(C3-C6)-Cycloalkylcarbonyl]heterocyclyl-(Ci-C 4 )-alkyl, Cyano (Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, (C 3 -C 6 )-Cycloalkyl, (C 3 -C 6 )-Halocycloalkyl, (C 4 -C 6 )-Cycloalkenyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkenyl- (Ci-C 4 )-alkyl, Hydroxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )- Haloalkoxy-(Ci-C 4 )-alkyl, Aryloxy-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkoxy-(Ci-C 4 )- alkyl, Heteroaryl-(Ci-C 4 )-alkoxy-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkoxy-(Ci-C 4 )- alkyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C 4 )-alkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylcarbonyloxy-(Ci-C 4 )-alkyl, Arylcarbonyloxy-(Ci-C 4 )-alkyl, R 4 is H, (Ci-C 4) -alkyl, (C 2 -C 4) alkenyl (Ci-C 4) alkyl, (C 2 -C 4) alkynyl, (Ci-C 4) - alkylcarbonyl, (C3-C6) cycloalkylcarbonyl, arylcarbonyl, heteroarylcarbonyl, (Ci-C4) alkoxycarbonyl, aryl (Ci-C4) -alkoxycarbonyl, (Ci-C4) - alkylaminocarbonyl, aryl (Ci-C 4 ) alkyl, Hetaroaryl- (Ci-C 4) alkyl, cyano (Ci-C 4) alkyl, (Ci-C 4) -haloalkyl, (C 3 -C 6) -cycloalkyl, (Ci-C 4 ) alkoxy (Ci-C 4) - alkyl, (Ci-C4) haloalkoxy (Ci-C 4) alkyl, (C 2 -C 4) alkynyl (Ci-C 4) alkyl, ( Ci-C 4) - alkoxycarbonyl (Ci-C 4) -alkyl, fluorine, (C 2 -C 4) alkyl, (Ci-C 4) alkoxy, (Ci-C4) alkoxycarbonyloxy, ( C 2 -C 4) - alkenyl, (C 2 -C 4) haloalkenyl, (C 2 -C 4) alkenyl, (Ci-C 4) alkyl, (C 2 -C 4) -alkynyl, (C 2 -C 4) alkynyl (Ci-C4) alkyl, aryl (Ci-C4) alkyl, bisaryl (Ci-C4) alkyl, aryl (Ci-C4) -alkoxyaryl- (Ci-C 4) alkyl, Aryloxyaryl- (Ci-C 4) alkyl, (Ci-C 4) -Alkoxyaryl- (Ci-C 4) -alkyl, heteroaryl- (Ci-C 4) alkyl, heterocyclyl - (Ci-C4) alkyl, N- (Ci-C4) - Alkylheterocyclyl- (Ci-C4) alkyl, N - [(Ci-C4) alkoxycarbonyl] heterocyclyl (Ci-C4) alkyl, N- (aryl (Ci-C 4) -alkoxycarbonyl) heterocyclyl- (Ci-C 4) alkyl, N- (arylcarbonyl) heterocyclyl- (Ci-C 4) alkyl, N - [(Ci- C 4) alkylcarbonyl] heterocyclyl (Ci-C4) alkyl, N - [(C3-C6) cycloalkylcarbonyl] heterocyclyl (Ci-C4) alkyl, cyano (Ci-C4) alkyl, (Ci -C 4) -haloalkyl, (C 3 -C 6) -cycloalkyl, (C 3 -C 6) halocycloalkyl, (C 4 -C 6) -cycloalkenyl, (C 3 -C 6) cycloalkyl (Ci- C 4) alkyl, (C 3 -C 6) cycloalkenyl (Ci-C 4) alkyl, hydroxy (Ci-C 4) alkyl, (Ci-C 4) alkoxy (Ci-C 4 ) alkyl, (Ci-C4) - haloalkoxy (Ci-C4) alkyl, aryloxy (Ci-C4) alkyl, aryl (Ci-C4) alkoxy (Ci-C4) - alkyl, heteroaryl (Ci-C 4) alkoxy (Ci-C 4) alkyl, (C 3 -C 6) cycloalkoxy (Ci-C 4) - alkyl, (C 3 -C 6) - cycloalkyl (Ci-C 4) alkoxy (Ci-C 4) alkyl, (Ci-C4) - alkylcarbonyloxy- (Ci-C 4) alkyl, arylcarbonyloxy (Ci-C 4) alkyl,

Heteroarylcarbonyloxy-(Ci-C 4 )-alkyl, (C 3 -C6)-Cycloalkylcarbonyloxy-(Ci-C 4 )- alkyl, Arylsulfonyloxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylsulfonyloxy-(Ci-C 4 )-alkyl, Hydrothio-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylthio-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkylthio- (Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkylthio-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkylthio- (Ci-C 4 )-alkyl, Arylthio-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylsulfinyl-(Ci-C 4 )-alkyl, (Ci-C 4 ) Alkylsulfonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkylsulfinyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Haloalkylsulfonyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkylsulfinyl-(Ci-C 4 )-alkyl, Aryl- (Ci-C 4 )-alkylsulfonyl-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkylsulfinyl-(Ci-C 4 )-alkyl, (C 3 -C6)-Cycloalkylsulfonyl-(Ci-C 4 )-alkyl, Aryl, Heteroaryl, Heterocyclyl, N- [(Ci-C 4 )-Alkyl]heterocyclyl, N-[(Ci-C 4 )-Alkoxycarbonyl]heterocyclyl, N-[Aryl- (Ci-C 4 )-alkoxycarbonyl]heterocyclyl, N-(Arylcarbonyl)heterocyclyl, N-[(Ci-C 4 )- Alkylcarbonyl]heterocyclyl, N-[(Ci-C 4 )-Cycloalkylcarbonyl]heterocyclyl, Hydroxycarbonyl, (Ci-C 4 )-Alkoxycarbonyl, (C 3 -C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkoxycarbonyl, Aryl-(Ci-C 4 )-alkoxycarbonyl, Heteroaryl-(Ci-C 4 )-alkoxycarbonyl, (Ci-C 4 )-Alkylaminocarbonyl, Heteroarylcarbonyloxy- (Ci-C4) alkyl, (C3-C6) -Cycloalkylcarbonyloxy- (Ci-C4) - alkyl, arylsulfonyloxy (Ci-C4) alkyl, (Ci-C 4) alkylsulfonyloxy ( Ci-C4) alkyl, Hydrothio- (Ci-C4) alkyl, (Ci-C4) alkylthio (Ci-C4) alkyl, (Ci-C4) -Haloalkylthio- (C 4) alkyl, aryl (Ci-C 4) alkylthio (Ci-C 4) alkyl, (C 3 -C 6) cycloalkylthio (Ci-C 4) alkyl, arylthio (C 4) alkyl, (Ci-C 4) alkylsulfinyl (Ci-C 4) alkyl, (Ci-C 4) alkylsulfonyl (Ci-C 4) alkyl, (Ci-C 4) -Haloalkylsulfinyl- ( Ci-C4) alkyl, (Ci-C4) - Haloalkylsulfonyl- (Ci-C4) alkyl, aryl (Ci-C4) alkylsulphinyl (Ci-C4) alkyl, aryl (Ci -C 4) alkylsulfonyl (Ci-C 4) alkyl, (C 3 -C 6) -Cycloalkylsulfinyl- (Ci-C 4) alkyl, (C 3 -C 6) -Cycloalkylsulfonyl- (Ci-C 4) alkyl, aryl, heteroaryl, heterocyclyl, N- [(Ci-C 4) -alkyl] heterocyclyl, N - [(Ci-C 4) alkoxycarbonyl] heterocyclyl, N- [aryl- (Ci-C 4) alkoxycarbonyl ] heterocyclyl, N- (arylcarbonyl) heterocyclyl, N - [(Ci-C4) - alkylcarbonyl] heterocyclyl, N - [(Ci-C 4) cycloalkylcarbonyl] heterocyclyl, hydroxycarbonyl, (Ci-C 4) alkoxycarbonyl, ( C 3 -C 6) cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C4) alkoxycarbonyl, aryl (Ci-C4) alkoxycarbonyl, heteroaryl (Ci-C4) -alkoxycarbonyl, (Ci C4) alkylaminocarbonyl,

Aminocarbonyl, Bis-(Ci-C 4 )-alkylaminocarbonyl, (C3-C6)- Cycloalkylaminocarbonyl, Aryl-(Ci-C 4 )-alkylaminocarbonyl, Aminocarbonyl, bis (Ci-C4) alkylaminocarbonyl, (C3-C6) - cycloalkylaminocarbonyl, aryl (Ci-C4) alkylaminocarbonyl,

Heteroarylaminocarbonyl, Cyano-(Ci-C 4 )-alkylaminocarbonyl, (Ci-C 4 )- Haloalkylaminocarbonyl, (C2-C 4 )-Alkinyl-(Ci-C 4 )-alkylaminocarbonyl, Heteroarylaminocarbonyl, cyano (Ci-C4) alkylaminocarbonyl, (Ci-C4) - Haloalkylaminocarbonyl, (C2-C4) alkynyl (Ci-C4) alkylaminocarbonyl,

Hydroxycarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxycarbonyl-(Ci-C 4 )-alkyl, (C3-C6)- Cycloalkoxycarbonyl-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkoxycarbonyl- (Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkoxycarbonyl-(Ci-C 4 )-alkyl, Heteroaryl-(Ci-C 4 )- alkoxycarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylaminocarbonyl-(Ci-C 4 )-alkyl, Aminocarbonyl-(Ci-C 4 )-alkyl, Bis-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkylaminocarbonyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )- alkylaminocarbonyl-(Ci-C 4 )-alkyl, Heteroarylaminocarbonyl-(Ci-C 4 )-alkyl, Cyano-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Haloalkylaminocarbonyl-(Ci-C 4 )-alkyl, (C2-C 4 )-Alkinyl-(Ci-C 4 )- alkylaminocarbonyl-(Ci-C 4 )-alkyl, Amino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylamino- (Ci-C 4 )-alkyl, (C2-C 4 )-Alkenylamino-(Ci-C 4 )-alkyl, Arylamino-(Ci-C 4 )-alkyl, Bis- (Ci-C 4 )-alkylamino-(Ci-C 4 )-alkyl, Bis-(C3-C6)-cycloalkylamino-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkylamino-(Ci-C 4 )-alkyl, Tris-Aryl-(Ci-C 4 )-alkylamino-(Ci-C 4 )- alkyl, (C3-C 6 )-Cycloalkylamino-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C 4 )- alkylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylcarbonylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Cycloalkylcarbonylamino-(Ci-C 4 )- alkyl, Arylcarbonylamino-(Ci-C 4 )-alkyl, Heteroarylcarbonylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxycarbonylamino-(Ci-C 4 )-alkyl, (C2-C 4 )-Alkenyloxycarbonylamino- (Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkoxycarbonylamino-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )- alkoxycarbonyl[N-(Ci-C 4 )-alkyl]amino-(Ci-C 4 )-alkyl, Heteroaryl-(Ci-C 4 )- alkoxycarbonylamino-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )- alkoxycarbonylamino-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkoxycarbonylamino- (Ci-C 4 )-alkyl, Aminocarbonylamino-(Ci-C 4 )-alkyl, Arylsulfonylamino-(Ci-C 4 )- alkyl, Heteroarylsulfonylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylsulfonylamino- (Ci-C 4 )-alkyl, (C3-C6)-Cycloalkylsulfonylamino-(Ci-C 4 )-alkyl, Aminoiminoamino-(Ci-C4)-alkyl, Arylsulfonylaminoiminoamino-(Ci-C4)-alkyl, (Ci-C4)-Alkylaminoiminoamino-(Ci-C4)-alkyl steht, für Wasserstoff, Halogen, (Ci-C 4 )-Alkyl, (Ci-C 4 )-Alkoxy, (C1-C4)- Hydroxycarbonyl (Ci-C4) alkyl, (Ci-C4) alkoxycarbonyl (Ci-C4) alkyl, (C3-C6) - Cycloalkoxycarbonyl- (Ci-C4) alkyl, (C3-C6 ) cycloalkyl- (Ci-C4) alkoxycarbonyl (Ci-C4) alkyl, aryl (Ci-C4) alkoxycarbonyl (Ci-C4) alkyl, heteroaryl (Ci-C4) - alkoxycarbonyl (Ci-C4) alkyl, (Ci-C4) alkylaminocarbonyl (Ci-C4) alkyl, aminocarbonyl (Ci-C4) alkyl, bis (Ci-C4) - alkylaminocarbonyl (Ci-C4) alkyl, (C3-C6) -Cycloalkylaminocarbonyl- (Ci-C4) alkyl, aryl (Ci-C4) - alkylaminocarbonyl (Ci-C4) alkyl, Heteroarylaminocarbonyl- (Ci-C4) alkyl, cyano (Ci-C4) alkylaminocarbonyl (Ci-C4) alkyl, (Ci-C4) - Haloalkylaminocarbonyl- (Ci-C4) alkyl, (C2 C4) alkynyl (Ci-C4) - alkylaminocarbonyl (Ci-C4) alkyl, amino (Ci-C4) alkyl, (Ci-C4) -alkylamino (Ci-C4) alkyl, (C2-C 4) -Alkenylamino- (Ci-C 4) alkyl, arylamino (Ci-C 4) alkyl, bis (Ci-C 4) alkylamino (Ci-C 4) - alkyl, bis (C3-C6) cycloalkylamino (Ci-C4) alkyl, aryl (Ci-C 4) alkylamino (C 4) alkyl, Tris-aryl (Ci-C 4 ) alkylamino (Ci-C 4) - alkyl, (C3-C6) cycloalkylamino (Ci-C 4) alkyl, (C 3 -C 6) cycloalkyl (Ci-C4) - alkylamino (Ci-C4) alkyl, (Ci-C4) -Haloalkylamino- (Ci-C4) alkyl, (Ci-C4) - alkylcarbonylamino (Ci-C4) alkyl, (Ci-C 4 ) -Cycloalkylcarbonylamino- (Ci-C4) - alkyl, arylcarbonylamino (Ci-C4) alkyl, Heteroarylcarbonylamino- (Ci-C4) alkyl, (Ci-C4) alkoxycarbonylamino (Ci-C4) alkyl, (C2-C4) -Alkenyloxycarbonylamino- (Ci-C4) alkyl, aryl (Ci-C4) alkoxycarbonylamino (Ci-C4) alkyl, aryl (Ci-C4) - alkoxycarbonyl [N- (Ci-C4) alkyl] amino (Ci-C4) alkyl, heteroaryl (Ci-C4) - alkoxycarbonylamino (Ci-C4) alkyl, (C3-C6) - cycloalkyl- (Ci-C4) - alkoxycarbonylamino (Ci-C4) alkyl, (C3-C6) -Cycloalkoxycarbonylamino- (Ci-C4) alkyl, aminocarbonylamino (Ci-C4) alkyl, arylsulfonylamino (Ci-C4) - alkyl, Heteroarylsulfonylamino- (Ci-C4) alkyl, (Ci-C4) alkylsulfonylamino (Ci-C4) alkyl, (C3-C6) -Cycloalkylsulfonylamino- (C 4) alkyl, Aminoiminoamino- (Ci-C4) alkyl, Arylsulfonylaminoiminoamino- (Ci-C4) alkyl, (Ci-C4) -Alkylaminoiminoamino- (Ci-C4) alkyl, represents hydrogen, halogen, (Ci- C 4) alkyl, (Ci-C4) alkoxy, (C1-C4) -

Alkoxycarbonyloxy, (C2-C4)-Alkenyl, (C2-C4)-Haloalkenyl, (C2-C4)-Alkenyl- (Ci-C 4 )-alkyl, (C2-C 4 )-Alkinyl, (C2-C4)-Alkinyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkyl, Bisaryl-(Ci-C 4 )-alkyl, Aryl-(Ci-C4)-alkoxyaryl-(Ci-C4)-alkyl, Aryloxyaryl-(Ci-C 4 )- alkyl, (Ci-C4)-Alkoxyaryl-(Ci-C4)-alkyl, Heteroaryl-(Ci-C4)-alkyl, Heterocyclyl- (Ci-C 4 )-alkyl, N-(Ci-C4)-Alkylheterocyclyl-(Ci-C4)-alkyl, N-[(Ci-C 4 )- Alkoxycarbonyl]heterocyclyl-(Ci-C4)-alkyl, N-(Aryl-(d-C4)- alkoxycarbonyl)heterocyclyl-(Ci-C4)-alkyl, N-(Arylcarbonyl)heterocyclyl- (Ci-C 4 )-alkyl, N-[(Ci-C4)-Alkylcarbonyl]heterocyclyl-(Ci-C4)-alkyl, N-[(C 3 -C 6 )- Cycloalkylcarbonyl]heterocyclyl-(Ci-C4)-alkyl, Cyano-(Ci-C4)-alkyl, (C1-C4)- Haloalkyl, (C 3 -C 6 )-Cycloalkyl, (C 3 -C 6 )-Halocycloalkyl, (C4-C 6 )-Cycloalkenyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C4)-alkyl, (C 3 -C 6 )-Cycloalkenyl-(Ci-C4)-alkyl, Hydroxy- (Ci-C 4 )-alkyl, (Ci-C4)-Alkoxy-(Ci-C4)-alkyl, (Ci-C4)-Haloalkoxy-(Ci-C4)-alkyl, Aryloxy-(Ci-C 4 )-alkyl, Aryl-(Ci-C4)-alkoxy-(Ci-C4)-alkyl, Heteroaryl-(Ci-C 4 )- alkoxy-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkoxy-(Ci-C4)-alkyl, (C 3 -C 6 )-Cycloalkyl- (Ci-C4)-alkoxy-(Ci-C4)-alkyl, (Ci-C4)-Alkylcarbonyloxy-(Ci-C4)-alkyl, Alkoxycarbonyloxy, (C2-C4) -alkenyl, (C2-C4) haloalkenyl, (C2-C4) -alkenyl (Ci-C4) alkyl, (C2-C4) alkynyl, (C2-C4) - alkynyl (Ci-C4) alkyl, aryl (Ci-C4) alkyl, bisaryl (Ci-C4) alkyl, aryl (Ci-C4) -alkoxyaryl- (Ci-C4) alkyl , Aryloxyaryl- (Ci-C4) - alkyl, (Ci-C4) -Alkoxyaryl- (Ci-C4) alkyl, heteroaryl (Ci-C4) alkyl, heterocyclyl (Ci-C4) alkyl, N - (Ci-C4) -Alkylheterocyclyl- (Ci-C4) alkyl, N - [(Ci-C4) - alkoxycarbonyl] heterocyclyl (Ci-C4) alkyl, N- (aryl (d-C4) - alkoxycarbonyl) heterocyclyl (Ci-C4) alkyl, N- (arylcarbonyl) heterocyclyl (Ci-C4) alkyl, N - [(Ci-C4) alkyl-carbonyl] heterocyclyl (Ci-C4) alkyl, N - [(C3-C6) - cycloalkylcarbonyl] heterocyclyl (Ci-C4) alkyl, cyano (Ci-C4) alkyl, (C1-C4) - haloalkyl, (C3-C6) -cycloalkyl, (C 3 -C 6) halocycloalkyl, (C4-C6) cycloalkenyl, (C 3 -C 6) cycloalkyl (Ci-C4) alkyl, (C 3 -C 6) cycloalkenyl (Ci- C4) alkyl, hydroxy (Ci-C4) alkyl, (Ci-C4) alkoxy (Ci-C4) alkyl, (Ci-C4) haloalkoxy (Ci-C4) alkyl, aryloxy (Ci-C4) alkyl, aryl (Ci-C4) alkoxy (Ci-C4) alkyl, heteroaryl (Ci-C4) - alkoxy (Ci-C4) alkyl, (C 3 C6) cycloalkoxy (Ci-C4) alkyl, (C3-C6) cycloalkyl (Ci-C4) alkoxy (Ci-C4) alkyl, (Ci-C4) alkylcarbonyloxy ( Ci-C4) alkyl,

Arylcarbonyloxy-(Ci-C4)-alkyl, Heteroarylcarbonyloxy-(Ci-C4)-alkyl, (C 3 -C6)- Cycloalkylcarbonyloxy-(Ci-C4)-alkyl, Arylsulfonyloxy-(Ci-C4)-alkyl, (C1-C4)- Alkylsulfonyloxy-(Ci-C4)-alkyl, Hydrothio-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylthio- (Ci-C 4 )-alkyl, (Ci-C4)-Haloalkylthio-(Ci-C4)-alkyl, Aryl-(Ci-C 4 )-alkylthio- (Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkylthio-(Ci-C4)-alkyl, Arylthio-(Ci-C 4 )-alkyl, Arylcarbonyloxy (Ci-C4) alkyl, Heteroarylcarbonyloxy- (Ci-C4) alkyl, (C3-C6) - Cycloalkylcarbonyloxy- (Ci-C4) alkyl, arylsulfonyloxy (Ci-C4) alkyl, (C1 C4) - alkylsulfonyloxy (Ci-C4) alkyl, Hydrothio- (Ci-C4) alkyl, (Ci-C4) alkylthio (Ci-C4) alkyl, (Ci-C4) -Haloalkylthio- (Ci-C4) alkyl, aryl (Ci-C4) alkylthio (Ci-C4) alkyl, (C3-C6) cycloalkylthio (Ci-C4) alkyl, arylthio (Ci -C 4) alkyl,

(Ci-C4)-Alkylsulfinyl-(Ci-C4)-alkyl, (Ci-C4)-Alkylsulfonyl-(Ci-C4)-alkyl, (C1-C4)- Haloalkylsulfinyl-(Ci-C4)-alkyl, (Ci-C4)-Haloalkylsulfonyl-(Ci-C4)-alkyl, Aryl- (Ci-C 4 )-alkylsulfinyl-(Ci-C4)-alkyl, Aryl-(Ci-C4)-alkylsulfonyl-(Ci-C4)-alkyl, (C 3 -C 6 )-Cycloalkylsulfinyl-(Ci-C4)-alkyl, (C 3 -C 6 )-Cycloalkylsulfonyl-(Ci-C4)- alkyl, Aryl, Heteroaryl, Heterocyclyl, N-[(Ci-C4)-Alkyl]heterocyclyl, N-[(Ci-C 4 )- Alkoxycarbonyl]heterocyclyl, N-[Aryl-(Ci-C4)-alkoxycarbonyl]heterocyclyl, N- (Arylcarbonyl)heterocyclyl, N-[(Ci-C4)-Alkylcarbonyl]heterocyclyl, N-[(Ci-C4)- Cycloalkylcarbonyl]heterocyclyl, Hydroxycarbonyl, (Ci-C4)-Alkoxycarbonyl, (C3-C6)-Cycloalkoxycarbonyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkoxycarbonyl, Aryl- (Ci-C 4 )-alkoxycarbonyl, Heteroaryl-(Ci-C 4 )-alkoxycarbonyl, (Ci-C 4 )- Alkylaminocarbonyl, Aminocarbonyl, Bis-(Ci-C 4 )-alkylaminocarbonyl, (C3-C6)- Cycloalkylaminocarbonyl, Aryl-(Ci-C 4 )-alkylaminocarbonyl, (Ci-C4) alkylsulphinyl (Ci-C4) alkyl, (Ci-C4) alkylsulphonyl (Ci-C4) alkyl, (C1-C4) - Haloalkylsulfinyl- (Ci-C4) alkyl, (Ci C4) -Haloalkylsulfonyl- (Ci-C4) alkyl, aryl (Ci-C4) alkylsulphinyl (Ci-C4) alkyl, aryl (Ci-C4) alkylsulphonyl (Ci-C4) alkyl , (C 3 -C 6) -Cycloalkylsulfinyl- (Ci-C4) alkyl, (C 3 -C 6) -Cycloalkylsulfonyl- (Ci-C4) - alkyl, aryl, heteroaryl, heterocyclyl, N - [(Ci-C4 ) alkyl] heterocyclyl, N - [(Ci-C4) - alkoxycarbonyl] heterocyclyl, N- [aryl- (Ci-C4) alkoxycarbonyl] heterocyclyl, N- (arylcarbonyl) heterocyclyl, N - [(Ci-C4) alkylcarbonyl] heterocyclyl, N - [(Ci-C4) - cycloalkylcarbonyl] heterocyclyl, hydroxycarbonyl, (Ci-C4) alkoxycarbonyl, (C3-C6) cycloalkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C4) alkoxycarbonyl, aryl (Ci-C4) alkoxycarbonyl, heteroaryl (Ci-C4) -alkoxycarbonyl, (Ci-C4) - alkylaminocarbonyl, aminocarbonyl, bis (Ci-C4) alkylaminocarbonyl, (C3 C6) - cycloalkylaminocarbonyl, aryl (Ci-C4) alkylaminocarbonyl,

Heteroarylaminocarbonyl, Cyano-(Ci-C 4 )-alkylaminocarbonyl, (Ci-C 4 )- Haloalkylaminocarbonyl, (C2-C 4 )-Alkinyl-(Ci-C 4 )-alkylaminocarbonyl, Heteroarylaminocarbonyl, cyano (Ci-C4) alkylaminocarbonyl, (Ci-C4) - Haloalkylaminocarbonyl, (C2-C4) alkynyl (Ci-C4) alkylaminocarbonyl,

Hydroxycarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxycarbonyl-(Ci-C 4 )-alkyl, (C3-C6)- Cycloalkoxycarbonyl-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )-alkoxycarbonyl- (Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkoxycarbonyl-(Ci-C 4 )-alkyl, Heteroaryl-(Ci-C 4 )- alkoxycarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylaminocarbonyl-(Ci-C 4 )-alkyl, Aminocarbonyl-(Ci-C 4 )-alkyl, Bis-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkylaminocarbonyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )- alkylaminocarbonyl-(Ci-C 4 )-alkyl, Heteroarylaminocarbonyl-(Ci-C 4 )-alkyl, Cyano-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Haloalkylaminocarbonyl-(Ci-C 4 )-alkyl, (C2-C 4 )-Alkinyl-(Ci-C 4 )- alkylaminocarbonyl-(Ci-C 4 )-alkyl, Amino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylamino- (Ci-C 4 )-alkyl, (C2-C 4 )-Alkenylamino-(Ci-C 4 )-alkyl, Arylamino-(Ci-C 4 )-alkyl, Bis- (Ci-C 4 )-alkylamino-(Ci-C 4 )-alkyl, Bis-(C3-C6)-cycloalkylamino-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkylamino-(Ci-C 4 )-alkyl, Tris-Aryl-(Ci-C 4 )-alkylamino-(Ci-C 4 )- alkyl, (C3-C 6 )-Cycloalkylamino-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkyl-(Ci-C 4 )- alkylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylcarbonylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Cycloalkylcarbonylamino-(Ci-C 4 )- alkyl, Arylcarbonylamino-(Ci-C 4 )-alkyl, Heteroarylcarbonylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkoxycarbonylamino-(Ci-C 4 )-alkyl, (C2-C 4 )-Alkenyloxycarbonylamino- (Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )-alkoxycarbonylamino-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )- alkoxycarbonyl[N-(Ci-C 4 )-alkyl]amino-(Ci-C 4 )-alkyl, Heteroaryl-(Ci-C 4 )- alkoxycarbonylamino-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkyl-(Ci-C 4 )- alkoxycarbonylamino-(Ci-C 4 )-alkyl, (C3-C6)-Cycloalkoxycarbonylamino- (Ci-C 4 )-alkyl, Aminocarbonylamino-(Ci-C 4 )-alkyl, Arylsulfonylamino-(Ci-C 4 )- alkyl, Heteroarylsulfonylamino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylsulfonylamino- (Ci-C 4 )-alkyl, (C3-C6)-Cycloalkylsulfonylamino-(Ci-C 4 )-alkyl, Aminoiminoamino-(Ci-C 4 )-alkyl, Arylsulfonylaminoiminoamino-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylaminoiminoamino-(Ci-C 4 )-alkyl steht, Hydroxycarbonyl (Ci-C4) alkyl, (Ci-C4) alkoxycarbonyl (Ci-C4) alkyl, (C3-C6) - Cycloalkoxycarbonyl- (Ci-C4) alkyl, (C3-C6 ) cycloalkyl- (Ci-C4) alkoxycarbonyl (Ci-C4) alkyl, aryl (Ci-C4) alkoxycarbonyl (Ci-C4) alkyl, heteroaryl (Ci-C4) - alkoxycarbonyl (Ci-C4) alkyl, (Ci-C4) alkylaminocarbonyl (Ci-C4) alkyl, aminocarbonyl (Ci-C4) alkyl, bis (Ci-C4) - alkylaminocarbonyl (Ci-C4) alkyl, (C3-C6) -Cycloalkylaminocarbonyl- (Ci-C4) alkyl, aryl (Ci-C4) - alkylaminocarbonyl (Ci-C4) alkyl, Heteroarylaminocarbonyl- (Ci-C4) alkyl, cyano (Ci-C4) alkylaminocarbonyl (Ci-C4) alkyl, (Ci-C4) - Haloalkylaminocarbonyl- (Ci-C4) alkyl, (C2 C4) alkynyl (Ci-C4) - alkylaminocarbonyl (Ci-C4) alkyl, amino (Ci-C4) alkyl, (Ci-C4) -alkylamino (Ci-C4) alkyl, (C2-C 4) -Alkenylamino- (Ci-C 4) alkyl, arylamino (Ci-C 4) alkyl, bis (Ci-C 4) alkylamino (Ci-C 4) - alkyl, bis (C3-C6) cycloalkylamino (Ci-C4) alkyl, aryl (Ci-C 4) alkylamino (C 4) alkyl, Tris-aryl (Ci-C 4 ) alkylamino (Ci-C 4) - alkyl, (C3-C6) cycloalkylamino (Ci-C 4) alkyl, (C 3 -C 6) cycloalkyl (Ci-C4) - alkylamino (Ci-C4) alkyl, (Ci-C4) -Haloalkylamino- (Ci-C4) alkyl, (Ci-C4) - alkylcarbonylamino (Ci-C4) alkyl, (Ci-C 4 ) -Cycloalkylcarbonylamino- (Ci-C4) - alkyl, arylcarbonylamino (Ci-C4) alkyl, Heteroarylcarbonylamino- (Ci-C4) alkyl, (Ci-C4) alkoxycarbonylamino (Ci-C4) alkyl, (C2-C4) -Alkenyloxycarbonylamino- (Ci-C4) alkyl, aryl (Ci-C4) alkoxycarbonylamino (Ci-C4) alkyl, aryl (Ci-C4) - alkoxycarbonyl [N- (Ci-C4) alkyl] amino (Ci-C4) alkyl, heteroaryl (Ci-C4) - alkoxycarbonylamino (Ci-C4) alkyl, (C3-C6) - cycloalkyl- (Ci-C4) - alkoxycarbonylamino (Ci-C4) alkyl, (C3-C6) -Cycloalkoxycarbonylamino- (Ci-C4) alkyl, aminocarbonylamino (Ci-C4) alkyl, arylsulfonylamino (Ci-C4) - alkyl, Heteroarylsulfonylamino- (Ci-C4) alkyl, (Ci-C4) alkylsulfonylamino (Ci-C4) alkyl, (C3-C6) -Cycloalkylsulfonylamino- (C 4) alkyl, Aminoiminoamino- (Ci-C 4) alkyl, Arylsulfonylaminoiminoamino- (Ci-C 4) alkyl, (Ci-C 4) -Alkylaminoiminoamino- (Ci-C 4) -alkyl,

R 6 und R 8 unabhängig voneinander für H, (Ci-C 4 )-Alkyl, (C 2 -C 4 )-Alkenyl-(Ci-C 4 )- alkyl, Aryl-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkyl, Heterocyciyi, Heterocyclyl-(Ci-C 4 )- alkyl, (Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylthio-(Ci-C 4 )-alkyl, (Ci-C 4 )- Haloalkyl stehen, R 6 and R 8 independently represent H, (Ci-C 4) -alkyl, (C 2 -C 4) alkenyl, (Ci-C 4) - alkyl, aryl (Ci-C 4) alkyl, ( C3-C6) -cycloalkyl, Heterocyciyi, heterocyclyl (Ci-C4) - alkyl, (Ci-C4) alkoxy (Ci-C4) alkyl, (Ci-C4) alkylthio ( Ci-C4) alkyl, (Ci-C4) - haloalkyl are,

R 41 für H oder Methyl steht, R 41 is H or methyl,

R 42 für (C 2 -C 4 )-Alkyl, (C 2 -C 4 )-Alkenyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylcarbonyl, R 42 is (C 2 -C 4) alkyl, (C 2 -C 4) alkenyl, (Ci-C 4) alkyl, (Ci-C 4) alkylcarbonyl,

Arylcarbonyl, Heteroarylcarbonyl, (Ci-C 4 )-Alkoxycarbonyl, Aryl-(Ci-C 4 )- alkoxycarbonyl, (Ci-C 4 )-Alkylaminocarbonyl, Aryl-(Ci-C 4 )-alkyl, Hetaroaryl- (Ci-C 4 )-alkyl, Cyano-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkyl, (C 3 -C 6 )-Cycloalkyl, Arylcarbonyl, heteroarylcarbonyl, (Ci-C4) alkoxycarbonyl, aryl (Ci-C4) - alkoxycarbonyl, (Ci-C4) alkylaminocarbonyl, aryl (Ci-C4) alkyl, Hetaroaryl- (C 4) -alkyl, cyano- (Ci-C 4) alkyl, (Ci-C 4) -haloalkyl, (C 3 -C 6) -cycloalkyl,

(Ci-C 4 )-Alkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )-Haloalkoxy-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkoxycarbonyl-(Ci-C 4 )-alkyl, Hydroxycarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkylaminocarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylcarbonyl-(Ci-C 4 )-alkyl steht, (Ci-C4) alkoxy (Ci-C4) alkyl, (Ci-C4) haloalkoxy (Ci-C4) alkyl, (Ci-C4) - alkoxycarbonyl (C 4 ) alkyl, hydroxycarbonyl (Ci-C 4) alkyl, (Ci-C4) - alkylaminocarbonyl (Ci-C 4) alkyl, (Ci-C 4) alkylcarbonyl (Ci-C 4) -alkyl stands,

R 43 für H oder Methyl steht, R 43 is H or methyl,

R 44 für Wasserstoff, (Ci-C 4 )-Alkyl, Aryl-(Ci-C 4 )-alkyl steht, R 44 is hydrogen, (Ci-C 4) alkyl, aryl (Ci-C 4) -alkyl,

R 51 und R 71 unabhängig voneinander für Wasserstoff und Methyl stehen, R 51 and R 71 independently represent hydrogen and methyl,

R 53 für Methyl steht, R 53 is methyl,

R 61 und R 81 unabhängig voneinander für Wasserstoff und Methyl stehen, R 63 für H, Methyl steht, R 61 and R 81 independently represent hydrogen and methyl, R 63 is H, methyl,

R 54 , R 64 , R 74 , R 84 unabhängig voneinander für Wasserstoff, Methyl stehen, wobei mindestens eine der Gruppen R 54 , R 64 , R 74 , R 84 für Methyl stehen muß, V für Hydroxycarbonyl, (Ci-C 4 )-Alkoxycarbonyl, Aryl-(Ci-C 4 )-alkoxycarbonyl, Aminocarbonyl, (Ci-C 4 )-Alkylaminocarbonyl, Bis-(Ci-C 4 )-alkylaminocarbonyl, (C3-C6)-Cycloalkylaminocarbonyl, Aryl-(Ci-C 4 )-alkylaminocarbonyl, Heteroaryl- (Ci-C 4 )-alkylaminocarbonyl, Cyano-(Ci-C 4 )-alkylaminocarbonyl steht, m für 0, 1 , 2, 3, 4 steht, p für 1 , 2, 3 steht, R 54, R 64, R 74, R 84 are independently hydrogen, methyl, at least one of R 54, R 64, R 74, R 84 must be methyl, V hydroxycarbonyl, (Ci-C4) alkoxycarbonyl, aryl (Ci-C4) alkoxycarbonyl, aminocarbonyl, (Ci-C4) alkylaminocarbonyl, bis (Ci-C4) alkylaminocarbonyl, (C3-C6) cycloalkylaminocarbonyl, aryl (Ci-C 4) alkylaminocarbonyl, heteroaryl (Ci-C4) alkylaminocarbonyl, cyano (Ci-C4) alkylaminocarbonyl, m represents 0, 1, 2, 3, 4, p is 1, 2, 3,

Y für Cyano, Hydroxycarbonyl, (Ci-C 4 )-Alkoxycarbonyl, (C3-C6)-Cycloalkyl- (Ci-C 4 )-alkoxycarbonyl, Aryl-(Ci-C 4 )-alkoxycarbonyl, Aminocarbonyl, (Ci-C 4 )- Alkylaminocarbonyl, Bis-(Ci-C 4 )-alkylaminocarbonyl, (C3-C6)- Cycloalkylaminocarbonyl, Aryl-(Ci-C 4 )-alkylaminocarbonyl, Heteroaryl-(Ci-C 4 )- alkylaminocarbonyl, Cyano-(Ci-C 4 )-alkylaminocarbonyl (C2-C 4 )-Alkinyl- Y represents cyano, hydroxycarbonyl, (Ci-C4) alkoxycarbonyl, (C3-C6) cycloalkyl (Ci-C4) alkoxycarbonyl, aryl (Ci-C4) alkoxycarbonyl, aminocarbonyl, (Ci-C 4 ) - alkylaminocarbonyl, bis (Ci-C4) alkylaminocarbonyl, (C3-C6) - cycloalkylaminocarbonyl, aryl (Ci-C4) alkylaminocarbonyl, heteroaryl (Ci-C4) - alkylaminocarbonyl, cyano (Ci C4) alkylaminocarbonyl (C2-C4) alkynyl

(Ci-C 4 )-alkylaminocarbonyl, (Ci-C 4 )-Alkoxycarbonylaminocarbonyl, Aryl- (Ci-C 4 )-alkoxycarbonylaminocarbonyl, Hydroxycarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )- Alkoxycarbonyl-(Ci-C 4 )-alkyl, (Ci-C 4 )-Alkylaminocarbonyl-(Ci-C 4 )-alkyl, Aminocarbonyl-(Ci-C 4 )-alkyl, Bis-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, (C 3 -C 6 )-Cycloalkylaminocarbonyl-(Ci-C 4 )-alkyl, Aryl-(Ci-C 4 )- alkylaminocarbonyl-(Ci-C 4 )-alkyl, Heteroaryl-(Ci-C 4 )-alkylaminocarbonyl- (Ci-C 4 )-alkyl, Cyano-(Ci-C 4 )-alkylaminocarbonyl-(Ci-C 4 )-alkyl, (C2-C 4 )- Alkenyloxycarbonyl, (C2-C 4 )-Alkenyloxycarbonyl-(Ci-C 4 )-alkyl, (C2-C 4 )- Alkenylaminocarbonyl, (C2-C 4 )-Alkenyl-(Ci-C 4 )-alkylaminocarbonyl, (C2-C 4 )- Alkenylaminocarbonyl-(Ci-C 4 )-alkyl, (C 2 -C 4 )-Alkenyl-(Ci-C 4 )- alkylaminocarbonyl-(Ci-C 4 )-alkyl steht. (Ci-C4) alkylaminocarbonyl, (Ci-C4) -Alkoxycarbonylaminocarbonyl, aryl (Ci-C4) -alkoxycarbonylaminocarbonyl, hydroxycarbonyl (Ci-C4) alkyl, (Ci-C4) - alkoxycarbonyl ( Ci-C 4) alkyl, (Ci-C4) alkylaminocarbonyl (Ci-C 4) alkyl, aminocarbonyl (Ci-C 4) alkyl, bis (Ci-C 4) -alkylaminocarbonyl- (C -C 4) alkyl, (C 3 -C 6) -Cycloalkylaminocarbonyl- (Ci-C 4) alkyl, aryl (Ci-C4) - alkylaminocarbonyl (Ci-C 4) -alkyl, heteroaryl- (Ci -C 4) alkylaminocarbonyl (Ci-C4) alkyl, cyano (Ci-C4) alkylaminocarbonyl (Ci-C4) alkyl, (C2-C4) - alkenyloxycarbonyl, (C2-C4 ) -Alkenyloxycarbonyl- (Ci-C4) alkyl, (C2-C4) - alkenylaminocarbonyl, (C2-C4) -alkenyl (Ci-C4) alkylaminocarbonyl, (C2-C4) - Alkenylaminocarbonyl- ( Ci-C 4) alkyl, (C 2 -C 4) alkenyl (Ci-C4) - alkylaminocarbonyl (Ci-C 4) alkyl. und Q weiterhin für eine der in der oben aufgeführten Tabelle spezifisch benannten Gruppierungen Q-1 .1 bis Q-24.15 steht Q and continue for a specifically named in the table above groups Q 1 .1 stands to Q 24.15

Im Hinblick auf die erfindungsgemäß verwendeten Verbindungen werden die vorstehend und weiter unten verwendeten Bezeichnungen erläutert. With regard to the compounds used in the invention, the above and further below used names are explained. Diese sind dem Fachmann geläufig und haben insbesondere die im Folgenden erläuterten Bedeutungen: These are familiar to the expert and have particularly explained in the following meanings:

Erfindungsgemäß steht "Arylsulfonyl" für gegebenenfalls substituiertes According to "arylsulfonyl" optionally substituted stands

Phenylsulfonyl oder gegebenenfalls substituiertes polycyclisches Arylsulfonyl, hier insbesondere gegebenenfalls substituiertes Naphthyl-sulfonyl, beispielsweise substituiert durch Fluor, Chlor, Brom, lod, Cyano, Nitro, Alkyl-, Haloalkyl-, Phenylsulphonyl or optionally substituted arylsulfonyl polycyclic, especially optionally substituted naphthyl-sulfonyl, such as substituted by fluorine, chlorine, bromine, iodine, cyano, nitro, alkyl, haloalkyl,

Haloalkoxy-, Amino-, Alkylamino-, Alkylcarbonylamino-, Dialkylamino- oder Alkoxy- gruppen. Haloalkoxy, amino, alkylamino, alkylcarbonylamino, dialkylamino or alkoxy groups.

Erfindungsgemäß steht "Cycloalkylsulfonyl" - in Alleinstellung oder als Bestandteil einer chemischen Gruppe - für gegebenenfalls substituiertes Cycloalkylsulfonyl, vorzugsweise mit 3 bis 6 Kohlenstoffatomen wie beispielsweise Cyclopropylsulfonyl, Cyclobutylsulfonyl, Cyclopentylsulfonyl oder Cyclohexylsulfonyl. According to the invention is "cycloalkylsulphonyl" - alone or as part of a chemical group - optionally substituted cycloalkylsulphonyl, preferably with 3 to 6 carbon atoms such as cyclopropylsulfonyl, Cyclobutylsulfonyl, cyclopentylsulfonyl or cyclohexylsulfonyl.

Erfindungsgemäß steht "Alkylsulfonyl" - in Alleinstellung oder als Bestandteil einer chemischen Gruppe - für geradkettiges oder verzweigtes Alkylsulfonyl, vorzugsweise mit 1 bis 8, oder mit 1 bis 6 Kohlenstoffatomen wie beispielsweise Methylsulfonyl, Ethylsulfonyl, n-Propylsulfonyl, Isopropylsulfonyl, n-Butylsulfonyl, Isobutylsulfonyl, sec-Butylsulfonyl und tert-Butylsulfonyl. According to the invention is "alkylsulfonyl" - alone or as part of a chemical group - chain or branched alkylsulfonyl preferably having from 1 to 8, or from 1 to 6 carbon atoms, such as methylsulfonyl, ethylsulfonyl, n-propylsulfonyl, isopropylsulfonyl, n-butylsulfonyl, Isobutylsulfonyl , sec-butylsulfonyl and tert-butylsulfonyl.

Erfindungsgemäß steht "Heteroarylsulfonyl" für gegebenenfalls substituiertes According to the invention is "heteroarylsulfonyl" represents optionally substituted

Pyridylsulfonyl, Pyrimidinylsulfonyl, Pyrazinylsulfonyl oder gegebenenfalls Pyridylsulfonyl, Pyrimidinylsulfonyl, Pyrazinylsulfonyl or possibly

substituiertes polycyclisches Heteroarylsulfonyl, hier insbesondere gegebenenfalls substituiertes Chinolinylsulfonyl, beispielsweise substituiert durch Fluor, Chlor, Brom, lod, Cyano, Nitro, Alkyl-, Haloalkyl-, Haloalkoxy-, Amino-, Alkylamino-, substituted polycyclic heteroarylsulfonyl, especially optionally substituted Chinolinylsulfonyl, for example, substituted by fluorine, chlorine, bromine, iodine, cyano, nitro, alkyl, haloalkyl, haloalkoxy, amino, alkylamino,

Alkylcarbonylamino-, Dialkylamino- oder Alkoxygruppen. Alkylcarbonylamino, dialkylamino or alkoxy.

Erfindungsgemäß steht "Alkylthio" - in Alleinstellung oder als Bestandteil einer chemischen Gruppe - für geradkettiges oder verzweigtes S-Alkyl, vorzugsweise mit 1 bis 8, oder mit 1 bis 6 Kohlenstoffatomen, wie beispielsweise Methylthio, Ethylthio, n- Propylthio, Isopropylthio, n-Butylthio, Isobutylthio, sec-Butylthio und tert-Butylthio. According to the invention is "alkylthio" - alone or as part of a chemical group - chain or branched S-alkyl, preferably with 1 to 8, or from 1 to 6 carbon atoms, such as methylthio, ethylthio, n-propylthio, isopropylthio, n- butylthio, isobutylthio, sec-butylthio and tert-butylthio. Alkenylthio bedeutet ein über ein Schwefelatom gebundenen Alkenylrest, Alkinylthio bedeutet ein über ein Schwefelatom gebundenen Aikinyirest, Cycloalkylthio bedeutet ein über ein Schwefelatom gebundenen Cycloalkylrest und Cycloalkenylthio bedeutet ein über ein Schwefelatom gebundenen Cycloalkenylrest. Alkenylthio means a bonded via a sulfur atom alkenyl group, an alkynylthio means is attached via a sulfur atom Aikinyirest, cycloalkylthio means a cycloalkyl radical is bonded via a sulfur atom and represents a cycloalkenylthio bonded via a sulfur atom cycloalkenyl.

„Alkoxy" bedeutet ein über ein Sauerstoffatom gebundenen Alkylrest, Alkenyloxy bedeutet ein über ein Sauerstoffatom gebundenen Alkenylrest, Alkinyloxy bedeutet ein über ein Sauerstoffatom gebundenen Aikinyirest, Cycloalkyloxy bedeutet ein über ein Sauerstoffatom gebundenen Cycloalkylrest und Cycloalkenyloxy bedeutet ein über ein Sauerstoffatom gebundenen Cycloalkenylrest. "Alkoxy" means a bonded via an oxygen atom alkyl group, alkenyloxy represents a bonded via an oxygen atom alkenyl group, alkynyloxy a bonded via an oxygen atom Aikinyirest, cycloalkyloxy means a bonded via an oxygen atom cycloalkyl and cycloalkenyloxy means a bonded via an oxygen atom cycloalkenyl.

Der Begriff„Aryl" bedeutet ein gegebenenfalls substituiertes mono-, bi- oder polycyclisches aromatisches System mit vorzugsweise 6 bis 14, insbesondere 6 bis 10 Ring-C-Atomen, beispielsweise Phenyl, Naphthyl, Anthryl, Phenanthrenyl, und ähnliches, vorzugsweise Phenyl. The term "aryl" means an optionally substituted mono-, bi- or polycyclic aromatic system having preferably 6 to 14, in particular 6 to 10 ring carbon atoms, for example phenyl, naphthyl, anthryl, phenanthrenyl, and the like, preferably phenyl.

Vom Begriff„gegebenenfalls substituiertes Aryl" sind auch mehrcyclische Systeme, wie Tetrahydronaphtyl, Indenyl, Indanyl, Fluorenyl, Biphenylyl, umfasst, wobei die Bindungsstelle am aromatischen System ist. Von der Systematik her ist„Aryl" in der Regel auch von dem Begriff„gegebenenfalls substituiertes Phenyl" umfasst. From the term "optionally substituted aryl" are also polycyclic systems, such as tetrahydronaphthyl, indenyl, indanyl, fluorenyl, biphenylyl, comprising the binding site on the aromatic system. From the scheme here is "aryl" as a rule, by the term "optionally substituted phenyl includes ".

Ein heterocyclischer Rest (Heterocyclyl) enthält mindestens einen heterocyclischen Ring (=carbocyclischer Ring, in dem mindestens ein C-Atom durch ein Heteroatom ersetzt ist, vorzugsweise durch ein Heteroatom aus der Gruppe N, O, S, P) der gesättigt, ungesättigt, teilgesättigt oder heteroaromatisch ist und dabei unsubstituiert oder substituiert sein kann, wobei die Bindungsstelle an einem Ringatom lokalisiert ist. A heterocyclic radical (heterocyclyl) contains at least one heterocyclic ring (= carbocyclic ring in which one carbon atom is replaced by a heteroatom at least, preferably by a heteroatom from the group N, O, S, P) of the saturated, unsaturated, partially saturated is or heteroaromatic and may be present are unsubstituted or substituted, where the binding site is located at a ring atom. Ist der Heterocyclylrest oder der heterocyclische Ring gegebenenfalls Is heterocyclyl or the heterocyclic ring optionally

substituiert, kann er mit anderen carbocyclischen oder heterocyclischen Ringen anneiiiert sein. substituted, it may be anneiiiert with other carbocyclic or heterocyclic rings. Im Falle von gegebenenfalls substituiertem Heterocyclyl werden auch mehrcyclische Systeme umfaßt, wie beispielsweise 8-Aza-bicyclo[3.2.1 ]octanyl, 8- Aza-bicyclo[2.2.2]octanyl oder 1 -Aza-bicyclo[2.2.1 ]heptyl. In the case of optionally substituted heterocyclyl also includes polycyclic systems, such as 8-aza-bicyclo [3.2.1] octanyl, 8-aza-bicyclo [2.2.2] octanyl or 1-aza-bicyclo [2.2.1] heptyl. Im Falle von In case of

gegebenenfalls substituiertem Heterocyclyl werden auch spirocyclische Systeme umfaßt, wie beispielsweise 1 -Oxa-5-aza-spiro[2.3]hexyl. optionally substituted heterocyclyl are also spirocyclic systems includes, such as 1 -Oxa-5-aza-spiro [2.3] hexyl. Wenn nicht anders definiert, enthält der heterocyclische Ring vorzugsweise 3 bis 9 Ringatome, insbesondere 3 bis 6 Ringatome, und ein oder mehrere, vorzugsweise 1 bis 4, insbesondere 1 , 2 oder 3 Heteroatome im heterocyclischen Ring, vorzugsweise aus der Gruppe N, 0, und S, wobei jedoch nicht zwei Sauerstoffatome direkt benachbart sein sollen, wie beispielsweise mit einem Heteroatom aus der Gruppe N, 0 und S 1 - oder 2- oder 3- Pyrrolidinyl, 3,4-Dihydro-2H-pyrrol-2- oder 3-yl, 2,3-Dihydro-1 H-pyrrol-1 - oder 2- oder Unless otherwise defined, the heterocyclic ring preferably contains from 3 to 9 ring atoms, especially 3 to 6 ring atoms, and one or more, preferably 1 to 4, in particular 1, 2 or 3 hetero atoms in the heterocyclic ring, preferably selected from the group N, 0 and S, but not two oxygen atoms to be directly adjacent, such as having a heteroatom from the group N, 0 and S 1 - or 2- or 3-pyrrolidinyl, 3,4-dihydro-2H-pyrrole-2 or 3 -yl, 2,3-dihydro-1 H-pyrrol-1 - or 2- or

3- oder 4- oder 5-yl; 3- or 4- or 5-yl; 2,5-Dihydro-1 H-pyrrol-1 - oder 2- oder 3-yl, 1 - oder 2- oder 3- oder 4-Piperidinyl; 2,5-dihydro-1 H-pyrrol-1 - or 2- or 3-yl, 1 - or 2- or 3- or 4-piperidinyl; 2,3,4,5-Tetrahydropyridin-2- oder 3- oder 4- oder 5-yl oder 6-yl; 2,3,4,5-tetrahydropyridine-2- or 3- or 4- or 5-yl or 6-yl; 1 ,2,3,6-Tetrahydropyridin-1 - oder 2- oder 3- oder 4- oder 5- oder 6-yl; 1, 2,3,6-tetrahydropyridine-1 - or 2- or 3- or 4- or 5- or 6-yl; 1 ,2,3,4- 1, 2,3,4

Tetrahydropyridin-1 - oder 2- oder 3- oder 4- oder 5- oder 6-yl; Tetrahydropyridin-1 - or 2- or 3- or 4- or 5- or 6-yl; 1 ,4-Dihydropyridin-1 - oder 2- oder 3- oder 4-yl; 1, 4-dihydropyridine-1 - or 2- or 3- or 4-yl; 2,3-Dihydropyridin-2- oder 3- oder 4- oder 5- oder 6-yl; 2,3-dihydropyridine-2- or 3- or 4- or 5- or 6-yl; 2,5- Dihydropyridin-2- oder 3- oder 4- oder 5- oder 6-yl, 1 - oder 2- oder 3- oder 4- Azepanyl; 2,5-dihydropyridine-2- or 3- or 4- or 5- or 6-yl, 1 - or 2- or 3- or 4-azepanyl; 2,3,4,5-Tetrahydro-1 H-azepin-1 - oder 2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3,4,5-tetrahydro-1 H-azepin-1 - or 2- or 3- or 4- or 5- or 6- or 7-yl; 2,3,4,7-Tetrahydro-1 H-azepin-1 - oder 2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3,4,7-tetrahydro-1 H-azepin-1 - or 2- or 3- or 4- or 5- or 6- or 7-yl; 2,3,6,7-Tetrahydro-1 H-azepin-1 - oder 2- oder 3- oder 4-yl; 2,3,6,7-tetrahydro-1 H-azepin-1 - or 2- or 3- or 4-yl; 3,4,5,6- Tetrahydro-2H-azepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 3,4,5,6-tetrahydro-2H-azepin-2- or 3- or 4- or 5- or 6- or 7-yl; 4,5-Dihydro-1 H- azepin-1 - oder 2- oder 3- oder 4-yl; 4,5-dihydro-1 H- azepin-1 - or 2- or 3- or 4-yl; 2,5-Dihydro-1 H-azepin-1 - oder -2- oder 3- oder 2,5-dihydro-1 H-azepin-1 - or 2- or 3- or

4- oder 5- oder 6- oder 7-yl; 4- or 5- or 6- or 7-yl; 2,7-Dihydro-1 H-azepin-1 - oder -2- oder 3- oder 4-yl; 2,7-dihydro-1 H-azepin-1 - or 2- or 3- or 4-yl; 2,3- Dihydro-1 H-azepin-1 - oder -2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3-dihydro-1 H-azepin-1 - or 2- or 3- or 4- or 5- or 6- or 7-yl; 3,4-Dihydro- 3,4-dihydro-

2H-azepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2H-azepin-2- or 3- or 4- or 5- or 6- or 7-yl; 3,6-Dihydro-2H-azepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 3,6-Dihydro-2H-azepin-2- or 3- or 4- or 5- or 6- or 7-yl; 5,6-Dihydro-2H-azepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 5,6-Dihydro-2H-azepin-2- or 3- or 4- or 5- or 6- or 7-yl; 4,5-Dihydro-3H-azepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 4,5-dihydro-3H-azepin-2- or 3- or 4- or 5- or 6- or 7-yl; 1 H-Azepin-1 - oder -2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 1 H-azepine-1 - or 2- or 3- or 4- or 5- or 6- or 7-yl; 2H- Azepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2H-azepine-2- or 3- or 4- or 5- or 6- or 7-yl; 3H-Azepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 3H-azepin-2- or 3- or 4- or 5- or 6- or 7-yl; 4H-Azepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl, 2- oder 3-Oxolanyl (= 2- oder 3-Tetrahydrofuranyl); 4H-azepine-2- or 3- or 4- or 5- or 6- or 7-yl, 2- or 3-oxolanyl (= 2- or 3-tetrahydrofuranyl); 2,3-Dihydrofuran-2- oder 3- oder 4- oder 5-yl; 2,3-dihydrofuran-2- or 3- or 4- or 5-yl; 2,5-Dihydrofuran-2- oder 3-yl, 2- oder 3- oder 4-Oxanyl (= 2- oder 3- oder 4-Tetrahydropyranyl); 2,5-dihydrofuran-2 or 3-yl, 2- or 3- or 4-Oxanyl (= 2- or 3- or 4-tetrahydropyranyl); 3,4-Dihydro-2H-pyran-2- oder 3- oder 4- oder 5- oder 6-yl; 3,4-dihydro-2H-pyran-2- or 3- or 4- or 5- or 6-yl; 3,6- Dihydro-2H-pyran-2- oder 3-oder 4- oder 5- oder 6-yl; 3,6-dihydro-2H-pyran-2- or 3- or 4- or 5- or 6-yl; 2H-Pyran-2- oder 3- oder 4- oder 5- oder 6-yl; 2H-pyran-2- or 3- or 4- or 5- or 6-yl; 4H-Pyran-2- oder 3- oder 4-yl, 2- oder 3- oder 4-Oxepanyl; 4H-pyran-2- or 3- or 4-yl, 2- or 3- or 4-oxepanyl; 2,3,4,5- Tetrahydrooxepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3,4,5-tetrahydro-2- or 3- or 4- or 5- or 6- or 7-yl; 2,3,4,7- Tetrahydrooxepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3,4,7- tetrahydro-2- or 3- or 4- or 5- or 6- or 7-yl; 2,3,6,7- Tetrahydrooxepin-2- oder 3- oder 4-yl; 2,3,6,7-tetrahydro-2- or 3- or 4-yl; 2,3-Dihydrooxepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3-Dihydrooxepin-2- or 3- or 4- or 5- or 6- or 7-yl; 4,5-Dihydrooxepin-2- oder 3- oder 4-yl; 4,5-Dihydrooxepin-2- or 3- or 4-yl; 2,5-Dihydrooxepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,5-Dihydrooxepin-2- or 3- or 4- or 5- or 6- or 7-yl; Oxepin-2- oder 3- oder 4- oder 5- oder 6- oder 7- yl; Oxepin-2- or 3- or 4- or 5- or 6- or 7-yl; 2- oder 3-Tetrahydrothiophenyl; 2- or 3-tetrahydrothiophenyl; 2,3-Dihydrothiophen-2- oder 3- oder 4- oder 5-yl; 2,3-dihydrothiophene-2-or 3- or 4- or 5-yl; 2,5-Dihydrothiophen-2- oder 3-yl; 2,5-dihydrothiophene-2 or 3-yl; Tetrahydro-2H-thiopyran-2- oder 3- oder 4-yl; Tetrahydro-2H-thiopyran-2- or 3- or 4-yl; 3,4- Dihydro-2H-thiopyran-2- oder 3- oder 4- oder 5- oder 6-yl; 3,4-dihydro-2H-thiopyran-2- or 3- or 4- or 5- or 6-yl; 3,6-Dihydro-2H- thiopyran-2- oder 3- oder 4- oder 5- oder 6-yl; 3,6-dihydro-2H-thiopyran-2- or 3- or 4- or 5- or 6-yl; 2H-Thiopyran-2- oder 3- oder 4- oder 5- oder 6-yl; 2H-thiopyran-2- or 3- or 4- or 5- or 6-yl; 4H-Thiopyran-2- oder 3- oder 4-yl. 4H-thiopyran-2- or 3- or 4-yl. Bevorzugte 3-Ring und 4-Ring- Heterocyclen sind beispielsweise 1 - oder 2-Aziridinyl, Oxiranyl, Thiiranyl, 1 - oder 2- oder 3-Azetidinyl, 2- oder 3-Oxetanyl, 2- oder 3-Thietanyl, 1 ,3-Dioxetan-2-yl. Preferred 3-ring and 4-ring heterocycles are, for example 1 - or 2-aziridinyl, oxiranyl, thiiranyl, 1 - or 2- or 3-azetidinyl, 2 or 3-oxetanyl, 2- or 3-thietanyl, 1, 3 -Dioxetan-2-yl. Weitere Beispiele für "Heterocyclyl" sind ein partiell oder vollständig hydrierter Further examples of "heterocyclyl" is a partially or fully hydrogenated

heterocyclischer Rest mit zwei Heteroatomen aus der Gruppe N, O und S, wie beispielsweise 1 - oder 2- oder 3- oder 4-Pyrazolidinyl; heterocyclic radical having two hetero atoms from the group N, O and S, such as 1 - or 2- or 3- or 4-pyrazolidinyl; 4,5-Dihydro-3H-pyrazol- 3- oder 4- oder 5-yl; 4,5-dihydro-3H-pyrazol-3- or 4- or 5-yl; 4,5-Dihydro-1 H-pyrazol-1 - oder 3- oder 4- oder 5-yl; 4,5-dihydro-1 H-pyrazol-1 - or 3- or 4- or 5-yl; 2,3-Dihydro- 1 H-pyrazol-1 - oder 2- oder 3- oder 4- oder 5-yl; 2,3-dihydro-1 H-pyrazol-1 - or 2- or 3- or 4- or 5-yl; 1 - oder 2- oder 3- oder 4- Imidazolidinyl; 1 - or 2- or 3- or 4-imidazolidinyl; 2,3-Dihydro-1 H-imidazol-1 - oder 2- oder 3- oder 4-yl; 2,3-dihydro-1 H-imidazol-1 - or 2- or 3- or 4-yl; 2,5-Dihydro-1 H- imidazol-1 - oder 2- oder 4- oder 5-yl; 2,5-dihydro-1 H- imidazol-1 - or 2- or 4- or 5-yl; 4,5-Dihydro-1 H-imidazol-1 - oder 2- oder 4- oder 5-yl; 4,5-dihydro-1 H-imidazol-1 - or 2- or 4- or 5-yl; Hexahydropyridazin-1 - oder 2- oder 3- oder 4-yl; Hexahydropyridazine-1 - or 2- or 3- or 4-yl; 1 ,2,3,4- Tetrahydropyridazin-1 - oder 2- oder 3- oder 4- oder 5- oder 6-yl; 1, 2,3,4-tetrahydropyridazine-1 - or 2- or 3- or 4- or 5- or 6-yl; 1 ,2,3,6- Tetrahydropyridazin-1 - oder 2- oder 3- oder 4- oder 5- oder 6-yl; 1, 2,3,6-tetrahydropyridazine-1 - or 2- or 3- or 4- or 5- or 6-yl; 1 ,4,5,6- Tetrahydropyridazin-1 - oder 3- oder 4- oder 5- oder 6-yl; 1, 4,5,6-tetrahydropyridazine-1 - or 3- or 4- or 5- or 6-yl; 3,4,5,6- Tetrahydropyridazin-3- oder 4- oder 5-yl; 3,4,5,6-tetrahydropyridazine-3 or 4 or 5-yl; 4,5-Dihydropyridazin-3- oder 4-yl; 4,5-dihydropyridazine-3- or 4-yl; 3,4- Dihydropyridazin-3- oder 4- oder 5- oder 6-yl; 3,4-dihydropyridazine-3- or 4- or 5- or 6-yl; 3,6-Dihydropyridazin-3- oder 4-yl; 3,6-dihydropyridazine-3- or 4-yl; 1 ,6- Dihydropyriazin-1 - oder 3- oder 4- oder 5- oder 6-yl; 1, 6- Dihydropyriazin-1 - or 3- or 4- or 5- or 6-yl; Hexahydropyrimidin-1 - oder 2- oder 3- oder 4-yl; Hexahydropyrimidine-1 - or 2- or 3- or 4-yl; 1 ,4,5,6-Tetrahydropyrimidin-1 - oder 2- oder 4- oder 5- oder 6-yl; 1, 4,5,6-tetrahydropyrimidine-1 - or 2- or 4- or 5- or 6-yl; 1 ,2,5,6-Tetrahydropyrimidin-1 - oder 2- oder 4- oder 5- oder 6-yl; 1, 2,5,6-tetrahydropyrimidine-1 - or 2- or 4- or 5- or 6-yl; 1 ,2,3,4- Tetrahydropyrimidin-1 - oder 2- oder 3- oder 4- oder 5- oder 6-yl; 1, 2,3,4-tetrahydropyrimidine-1 - or 2- or 3- or 4- or 5- or 6-yl; 1 ,6- Dihydropyrimidin-1 - oder 2- oder 4- oder 5- oder 6-yl; 1, 6- dihydropyrimidine-1 - or 2- or 4- or 5- or 6-yl; 1 ,2-Dihydropyrimidin-1 - oder 2- oder 4- oder 5- oder 6-yl; 1, 2-dihydropyrimidine-1 - or 2- or 4- or 5- or 6-yl; 2,5-Dihydropyrimidin-2- oder 4- oder 5-yl; 2,5-dihydropyrimidine-2, or 4-, or 5-yl; 4,5- 4,5-

Dihydropyrimidin- 4- oder 5- oder 6-yl; Dihydropyrimidine 4- or 5- or 6-yl; 1 ,4-Dihydropyrimidin-1 - oder 2- oder 4- oder 5- oder 6-yl; 1, 4-dihydropyrimidine-1 - or 2- or 4- or 5- or 6-yl; 1 - oder 2- oder 3-Piperazinyl; 1 - or 2- or 3-piperazinyl; 1 ,2,3,6-Tetrahydropyrazin-1 - oder 2- oder 3- oder 5- oder 6-yl; 1, 2,3,6-tetrahydropyrazine-1 - or 2- or 3- or 5- or 6-yl; 1 ,2,3,4-Tetrahydropyrazin-1 - oder 2- oder 3- oder 4- oder 5- oder 6-yl; 1, 2,3,4-tetrahydropyrazine-1 - or 2- or 3- or 4- or 5- or 6-yl; 1 ,2-Dihydropyrazin-1 - oder 2- oder 3- oder 5- oder 6-yl; 1, 2-dihydropyrazine-1 - or 2- or 3- or 5- or 6-yl; 1 ,4- Dihydropyrazin-1 - oder 2- oder 3-yl; 1, 4-dihydropyrazine-1 - or 2- or 3-yl; 2,3-Dihydropyrazin-2- oder 3- oder 5- oder 6-yl; 2,3-dihydropyrazine-2- or 3- or 5- or 6-yl;

2.5- Dihydropyrazin-2- oder 3-yl; 2.5- dihydropyrazine 2- or 3-yl; 1 ,3-Dioxolan-2- oder 4- oder 5-yl; 1, 3-dioxolan-2- or 4- or 5-yl; 1 ,3-Dioxol-2- oder 4-yl; 1, 3-dioxole-2 or 4-yl; 1 ,3-Dioxan-2- oder 4- oder 5-yl; 1, 3-dioxan-2- or 4- or 5-yl; 4H-1 ,3-Dioxin-2- oder 4- oder 5- oder 6-yl; 4H-1, 3-dioxin-2- or 4- or 5- or 6-yl; 1 ,4- 1, 4-

Dioxan-2- oder 3- oder 5- oder 6-yl; Dioxan-2- or 3- or 5- or 6-yl; 2,3-Dihydro-1 ,4-dioxin-2- oder 3- oder 5- oder 6- yl; 2,3-dihydro-1, 4-dioxin-2- or 3- or 5- or 6-yl; 1 ,4-Dioxin-2- oder 3-yl; 1, 4-dioxin-2 or 3-yl; 1 ,2-Dithiolan-3- oder 4-yl; 1, 2-dithiolane-3 or 4-yl; 3H-1 ,2-Dithiol-3- oder 4- oder 5- yl; 3H-1, 2-dithiol-3-or 4- or 5-yl; 1 ,3-Dithiolan-2- oder 4-yl; 1, 3-dithiolane-2 or 4-yl; 1 ,3-Dithiol-2- oder 4-yl; 1, 3-dithiol-2 or 4-yl; 1 ,2-Dithian-3- oder 4-yl; 1, 2-dithian-3 or 4-yl; 3,4- Dihydro-1 ,2-dithiin-3- oder 4- oder 5- oder 6-yl; 3,4-dihydro-1, 2-dithiin-3- or 4- or 5- or 6-yl; 3,6-Dihydro-1 ,2-dithiin-3- oder 4-yl; 3,6-dihydro-1, 2-dithiin-3- or 4-yl; 1 ,2-Dithiin-3- oder 4-yl; 1, 2-dithiine-3- or 4-yl; 1 ,3-Dithian-2- oder 4- oder 5-yl; 1, 3-dithian-2- or 4- or 5-yl; 4H-1 ,3-Dithiin-2- oder 4- oder 5- oder 6-yl; 4H-1, 3-dithiine-2- or 4- or 5- or 6-yl; lsoxazolidin-2- oder 3- oder 4- oder 5-yl; lsoxazolidin-2- or 3- or 4- or 5-yl; 2,3-Dihydroisoxazol-2- oder 3- oder 4- oder 5-yl; 2,3-dihydroisoxazol-2- or 3- or 4- or 5-yl; 2,5-Dihydroisoxazol-2- oder 3- oder 4- oder 5-yl; 2,5-dihydroisoxazol-2- or 3- or 4- or 5-yl; 4,5- Dihydroisoxazol-3- oder 4- oder 5-yl; 4,5-dihydroisoxazol-3- or 4- or 5-yl; 1 ,3-Oxazolidin-2- oder 3- oder 4- oder 5-yl; 1, 3-oxazolidin-2- or 3- or 4- or 5-yl; 2,3- Dihydro-1 ,3-oxazol-2- oder 3- oder 4- oder 5-yl; 2,3-dihydro-1, 3-oxazol-2- or 3- or 4- or 5-yl; 2,5-Dihydro-1 ,3-oxazol-2- oder 4- oder 5-yl; 2,5-dihydro-1, 3-oxazol-2- or 4- or 5-yl; 4,5-Dihydro-1 ,3-oxazol-2- oder 4- oder 5-yl; 4,5-dihydro-1, 3-oxazol-2- or 4- or 5-yl; 1 ,2-Oxazinan-2- oder 3- oder 1, 2-oxazinan-2- or 3- or

4- oder 5- oder 6-yl; 4- or 5- or 6-yl; 3,4-Dihydro-2H-1 ,2-oxazin-2- oder 3- oder 4- oder 5- oder 6-yl; 3,4-dihydro-2H-1, 2-oxazin-2- or 3- or 4- or 5- or 6-yl;

3.6- Dihydro-2H-1 ,2-oxazin-2- oder 3- oder 4- oder 5- oder 6-yl; 3.6- dihydro-2H-1, 2-oxazin-2- or 3- or 4- or 5- or 6-yl; 5,6-Dihydro-2H-1 ,2- oxazin-2- oder 3- oder 4- oder 5- oder 6-yl; 5,6-dihydro-2H-1, 2- oxazin-2- or 3- or 4- or 5- or 6-yl; 5,6-Dihydro-4H-1 ,2-oxazin-3- oder 4- oder 5- oder 6-yl; 5,6-dihydro-4H-1, 2-oxazin-3- or 4- or 5- or 6-yl; 2H-1 ,2-Oxazin-2- oder 3- oder 4- oder 5- oder 6-yl; 2H-1, 2-oxazine-2- or 3- or 4- or 5- or 6-yl; 6H-1 ,2-Oxazin- 3- oder 4- oder 5- oder 6-yl; 6H-1, 2-oxazine, 3- or 4- or 5- or 6-yl; 4H-1 ,2-Oxazin-3- oder 4- oder 5- oder 6-yl; 4H-1, 2-oxazin-3- or 4- or 5- or 6-yl; 1 ,3- 1, 3-

Oxazinan-2- oder 3- oder 4- oder 5- oder 6-yl; Oxazinan-2- or 3- or 4- or 5- or 6-yl; 3,4-Dihydro-2H-1 ,3-oxazin-2- oder 3- oder 4- oder 5- oder 6-yl; 3,4-dihydro-2H-1, 3-oxazin-2- or 3- or 4- or 5- or 6-yl; 3,6-Dihydro-2H-1 ,3-oxazin-2- oder 3- oder 4- oder 5- oder 6-yl; 3,6-dihydro-2H-1, 3-oxazin-2- or 3- or 4- or 5- or 6-yl; 5,6-Dihydro-2H-1 ,3-oxazin-2- oder 4- oder 5- oder 6-yl; 5,6-dihydro-2H-1, 3-oxazin-2- or 4- or 5- or 6-yl; 5,6-Dihydro-4H-1 ,3- oxazin-2- oder 4- oder 5- oder 6-yl; 5,6-dihydro-4H-1, 3- oxazin-2- or 4- or 5- or 6-yl; 2H-1 ,3-Oxazin-2- oder 4- oder 5- oder 6-yl; 2H-1, 3-oxazin-2- or 4- or 5- or 6-yl; 6H- 1 ,3-Oxazin-2- oder 4- oder 5- oder 6-yl; 6H-1, 3-oxazin-2- or 4- or 5- or 6-yl; 4H-1 ,3-Oxazin-2- oder 4- oder 5- oder 6-yl; 4H-1, 3-oxazin-2- or 4- or 5- or 6-yl; Morpholin-2- oder 3- oder 4-yl; Morpholin-2- or 3- or 4-yl; 3,4-Dihydro-2H-1 ,4-oxazin-2- oder 3- oder 4- oder 5- oder 6-yl; 3,4-dihydro-2H-1, 4-oxazin-2- or 3- or 4- or 5- or 6-yl; 3,6-Dihydro-2H-1 ,4-oxazin-2- oder 3- oder 5- oder 6-yl; 3,6-dihydro-2H-1, 4-oxazin-2- or 3- or 5- or 6-yl; 2H-1 ,4-oxazin-2- oder 3- oder 5- oder 6-yl; 2H-1, 4-oxazin-2- or 3- or 5- or 6-yl; 4H-1 ,4-oxazin-2- oder 3-yl; 4H-1, 4-oxazin-2- or 3-yl; 1 ,2-Oxazepan-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 1, 2-oxazepan-2- or 3- or 4- or 5- or 6- or 7-yl; 2,3,4,5-Tetrahydro-1 ,2-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3,4,5-tetrahydro-1, 2-oxazepin-2- or 3- or 4- or 5- or 6- or 7-yl; 2,3,4,7-Tetrahydro-1 ,2-oxazepin-2- oder 3- oder 4- oder 5- oder 2,3,4,7-tetrahydro-1, 2-oxazepin-2- or 3- or 4- or 5- or

6- oder 7-yl; 6- or 7-yl; 2,3,6,7-Tetrahydro-1 ,2-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 2,3,6,7-tetrahydro-1, 2-oxazepin-2- or 3- or 4- or 5- or 6- or

7- yl; 7-yl; 2,5,6,7-Tetrahydro-1 ,2-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,5,6,7-tetrahydro-1, 2-oxazepin-2- or 3- or 4- or 5- or 6- or 7-yl; 4,5,6,7-Tetrahydro-1 ,2-oxazepin-3- oder 4- oder 5- oder 6- oder 7-yl; 4,5,6,7-tetrahydro-1, 2-oxazepin-3, or 4- or 5- or 6- or 7-yl; 2,3-Dihydro- 2,3-dihydro

1 .2- oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 1 .2- oxazepine-2- or 3- or 4- or 5- or 6- or 7-yl; 2,5-Dihydro-1 ,2-oxazepin- 2,5-dihydro-1, 2-oxazepin-

2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2- or 3- or 4- or 5- or 6- or 7-yl; 2,7-Dihydro-1 ,2-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,7-dihydro-1, 2-oxazepin-2- or 3- or 4- or 5- or 6- or 7-yl; 4,5-Dihydro-1 ,2-oxazepin-3- oder 4- oder 5- oder 6- oder 7-yl; 4,5-dihydro-1, 2-oxazepin-3, or 4- or 5- or 6- or 7-yl; 4,7-Dihydro-1 ,2-oxazepin-3- oder 4- oder 5- oder 6- oder 7-yl; 4,7-dihydro-1, 2-oxazepin-3, or 4- or 5- or 6- or 7-yl; 6,7-Dihydro-1 ,2- oxazepin-3- oder 4- oder 5- oder 6- oder 7-yl; 6,7-dihydro-1, 2-oxazepin-3, or 4- or 5- or 6- or 7-yl; 1 ,2-Oxazepin-3- oder 4- oder 5- oder 1, 2-oxazepine-3- or 4- or 5- or

6- oder 7-yl; 6- or 7-yl; 1 ,3-Oxazepan-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 1, 3-oxazepan-2- or 3- or 4- or 5- or 6- or 7-yl; 2,3,4,5- Tetrahydro-1 ,3-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3,4,5-tetrahydro-1, 3-oxazepin-2- or 3- or 4- or 5- or 6- or 7-yl; 2,3,4,7- Tetrahydro-1 ,3-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3,4,7- tetrahydro-1, 3-oxazepin-2- or 3- or 4- or 5- or 6- or 7-yl; 2,3,6,7- Tetrahydro-1 ,3-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3,6,7-tetrahydro-1, 3-oxazepin-2- or 3- or 4- or 5- or 6- or 7-yl; 2,5,6,7- 2,5,6,7

Tetrahydro-1 ,3-oxazepin-2- oder 4- oder 5- oder 6- oder 7-yl; Tetrahydro-1, 3-oxazepin-2- or 4- or 5- or 6- or 7-yl; 4,5,6,7-Tetrahydro-1 ,3- oxazepin-2- oder 4- oder 5- oder 6- oder 7-yl; 4,5,6,7-tetrahydro-1, 3-oxazepin-2- or 4- or 5- or 6- or 7-yl; 2,3-Dihydro-1 ,3-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3-dihydro-1, 3-oxazepin-2- or 3- or 4- or 5- or 6- or 7-yl; 2,5-Dihydro-1 ,3-oxazepin-2- oder 4- oder 5- oder 6- oder 7-yl; 2,5-dihydro-1, 3-oxazepin-2- or 4- or 5- or 6- or 7-yl; 2,7-Dihydro-1 ,3-oxazepin-2- oder 4- oder 5- oder 6- oder 7-yl; 2,7-dihydro-1, 3-oxazepin-2- or 4- or 5- or 6- or 7-yl; 4,5-Dihydro- 1 ,3-oxazepin-2- oder 4- oder 5- oder 6- oder 7-yl; 4,5-dihydro-1, 3-oxazepin-2- or 4- or 5- or 6- or 7-yl; 4,7-Dihydro-1 ,3-oxazepin-2- oder 4- oder 5- oder 6- oder 7-yl; 4,7-dihydro-1, 3-oxazepin-2- or 4- or 5- or 6- or 7-yl; 6,7-Dihydro-1 ,3-oxazepin-2- oder 4- oder 5- oder 6- oder 6,7-dihydro-1, 3-oxazepin-2- or 4- or 5- or 6- or

7- yl; 7-yl; 1 ,3-Oxazepin-2- oder 4- oder 5- oder 6- oder 7-yl; 1, 3-oxazepine-2- or 4- or 5- or 6- or 7-yl; 1 ,4-Oxazepan-2- oder 3- oder 5- oder 6- oder 7-yl; 1, 4-oxazepan-2- or 3- or 5- or 6- or 7-yl; 2,3,4,5-Tetrahydro-1 ,4-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3,4,5-tetrahydro-1, 4-oxazepine-2- or 3- or 4- or 5- or 6- or 7-yl; 2,3,4,7-Tetrahydro-1 ,4-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 2,3,4,7-tetrahydro-1, 4-oxazepine-2- or 3- or 4- or 5- or 6- or 7-yl; 2,3,6,7-Tetrahydro-1 ,4-oxazepin-2- oder 3- oder 5- oder 6- oder 7-yl; 2,3,6,7-tetrahydro-1, 4-oxazepine-2- or 3- or 5- or 6- or 7-yl;

2,5,6,7-Tetrahydro-1 ,4-oxazepin-2- oder 3- oder 5- oder 6- oder 7-yl; 2,5,6,7-tetrahydro-1, 4-oxazepine-2- or 3- or 5- or 6- or 7-yl; 4,5,6,7- Tetrahydro-1 ,4-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 4,5,6,7-tetrahydro-1, 4-oxazepine-2- or 3- or 4- or 5- or 6- or 7-yl; 2,3-Dihydro- 1 ,4-oxazepin-2- oder 3- oder 5- oder 6- oder 7-yl; 2,3-dihydro-1, 4-oxazepine-2- or 3- or 5- or 6- or 7-yl; 2,5-Dihydro-1 ,4-oxazepin-2- oder 2,5-dihydro-1, 4-oxazepin-2 or

3- oder 5- oder 6- oder 7-yl; 3- or 5- or 6- or 7-yl; 2,7-Dihydro-1 ,4-oxazepin-2- oder 3- oder 5- oder 6- oder 7-yl; 2,7-dihydro-1, 4-oxazepine-2- or 3- or 5- or 6- or 7-yl; 4,5-Dihydro-1 ,4-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; 4,5-dihydro-1, 4-oxazepine-2- or 3- or 4- or 5- or 6- or 7-yl; 4,7- 4,7

Dihydro-1 ,4-oxazepin-2- oder 3- oder 4- oder 5- oder 6- oder 7-yl; Dihydro-1, 4-oxazepine-2- or 3- or 4- or 5- or 6- or 7-yl; 6,7-Dihydro-1 ,4- oxazepin-2- oder 3- oder 5- oder 6- oder 7-yl; 6,7-dihydro-1, 4-oxazepine-2- or 3- or 5- or 6- or 7-yl; 1 ,4-Oxazepin-2- oder 3- oder 5- oder 6- oder 7-yl; 1, 4-oxazepine-2- or 3- or 5- or 6- or 7-yl; lsothiazolidin-2- oder 3- oder 4- oder 5-yl; lsothiazolidin-2- or 3- or 4- or 5-yl; 2,3-Dihydroisothiazol-2- oder 2,3-Dihydroisothiazol-2 or

3- oder 4- oder 5-yl; 3- or 4- or 5-yl; 2,5-Dihydroisothiazol-2- oder 3- oder 4- oder 5-yl; 2,5-Dihydroisothiazol-2- or 3- or 4- or 5-yl; 4,5- Dihydroisothiazol-3- oder 4- oder 5-yl; 4,5 Dihydroisothiazol-3- or 4- or 5-yl; 1 ,3-Thiazolidin-2- oder 3- oder 4- oder 5-yl; 1, 3-thiazolidine-2- or 3- or 4- or 5-yl;

2.3- Dihydro-1 ,3-thiazol-2- oder 3- oder 4- oder 5-yl; 2.3- dihydro-1, 3-thiazol-2- or 3- or 4- or 5-yl; 2,5-Dihydro-1 ,3-thiazol-2- oder 2,5-dihydro-1, 3-thiazol-2- or

4- oder 5-yl; 4- or 5-yl; 4,5-Dihydro-1 ,3-thiazol-2- oder 4- oder 5-yl; 4,5-dihydro-1, 3-thiazol-2- or 4- or 5-yl; 1 ,3-Thiazinan-2- oder 3- oder 4- oder 5- oder 6-yl; 1, 3-Thiazinan-2- or 3- or 4- or 5- or 6-yl; 3,4-Dihydrc-2H-1 ,3-thiazin-2- oder 3- oder 4- oder 5- oder 6-yl; 3,4-Dihydrc-2H-1, 3-thiazin-2- or 3- or 4- or 5- or 6-yl; 3,6-Dihydrc-2H-1 ,3-thiazin-2- oder 3- oder 4- oder 5- oder 6-yl; 3,6-Dihydrc-2H-1, 3-thiazin-2- or 3- or 4- or 5- or 6-yl; 5,6-Dihydro-2H- 1 ,3-thiazin-2- oder 4- oder 5- oder 6-yl; 5,6-dihydro-2H-1, 3-thiazin-2- or 4- or 5- or 6-yl; 5,6-Dihydrc-4H-1 ,3-thiazin-2- oder 4- oder 5- oder 6-yl; 5,6-Dihydrc-4H-1, 3-thiazin-2- or 4- or 5- or 6-yl; 2H-1 ,3-Thiazin-2- oder 4- oder 5- oder 6-yl; 2H-1, 3-thiazine-2- or 4- or 5- or 6-yl; 6H-1 ,3-Thiazin-2- oder 4- oder 5- oder 6-yl; 6H-1, 3-thiazine-2- or 4- or 5- or 6-yl; 4H-1 ,3-Thiazin-2- oder 4- oder 5- oder 6-yl. 4H-1, 3-thiazine-2- or 4- or 5- or 6-yl. Weitere Beispiele für Additional examples of

"Heterocyclyl" sind ein partiell oder vollständig hydrierter heterocyclischer Rest mit 3 Heteroatomen aus der Gruppe N, 0 und S, wie beispielsweise 1 ,4,2-Dioxazolidin-2- oder 3- oder 5-yl; "Heterocyclyl" means a partially or fully hydrogenated heterocyclic radical having 3 heteroatoms from the group N, 0 and S, such as 1, 4,2-dioxazolidine-2- or 3- or 5-yl; 1 ,4,2-Dioxazol-3- oder 5-yl; 1, 4,2-dioxazole-3- or 5-yl; 1 ,4,2-Dioxazinan-2- oder -3- oder 5- oder 6-yl; 1, 4,2-Dioxazinan-2- or -3- or 5- or 6-yl; 5,6-Dihydro-1 ,4,2-dioxazin-3- oder 5- oder 6-yl; 5,6-dihydro-1, 4,2-dioxazin-3 or 5- or 6-yl; 1 ,4,2-Dioxazin-3- oder 5- oder 6-yl; 1, 4,2-dioxazine 3- or 5- or 6-yl; 1 ,4,2-Dioxazepan-2- oder 3- oder 5- oder 6- oder 7-yl; 1, 4,2-Dioxazepan-2- or 3- or 5- or 6- or 7-yl; 6,7-Dihydro-5H- 1 ,4,2-Dioxazepin-3- oder 5- oder 6- oder 7-yl; 6,7-dihydro-5H-1, 4,2-Dioxazepin-3- or 5- or 6- or 7-yl; 2,3-Dihydro-7H-1 ,4,2-Dioxazepin-2- oder 3- oder 5- oder 6- oder 7-yl; 2,3-dihydro-7H-1, 4,2-Dioxazepin-2- or 3- or 5- or 6- or 7-yl; 2,3-Dihydro-5H-1 ,4,2-Dioxazepin-2- oder 3- oder 5- oder 6- oder 7-yl; 2,3-dihydro-5H-1, 4,2-Dioxazepin-2- or 3- or 5- or 6- or 7-yl; 5H-1 ,4,2-Dioxazepin-3- oder 5- oder 6- oder 7-yl; 5H-1, 4,2-Dioxazepin-3- or 5- or 6- or 7-yl; 7H-1 ,4,2- Dioxazepin-3- oder 5- oder 6- oder 7-yl. 7H-1, 4,2- Dioxazepin-3- or 5- or 6- or 7-yl.

Wenn ein Grundkörper "durch einen oder mehrere Reste" aus einer Aufzählung von Resten (= Gruppe) oder einer generisch definierten Gruppe von Resten substituiert ist, so schließt dies jeweils die gleichzeitige Substitution durch mehrere gleiche und/oder strukturell unterschiedliche Reste ein. When a body is substituted "by one or more radicals" from a list of radicals (= group) or a generically defined group of radicals, this includes in each case the simultaneous substitution by a plurality of identical and / or structurally different radicals.

Handelt es sich es sich um einen teilweise oder vollständig gesättigten Stickstoff- Heterocyclus, so kann dieser sowohl über Kohlenstoff als auch über den Stickstoff mit dem Rest des Moleküls verknüpft sein. If, it is a partially or fully saturated nitrogen heterocycle, this may be linked both carbon and nitrogen through the with the rest of the molecule. Als Substituenten für einen substituierten heterocyclischen Rest kommen die weiter unten genannten Substituenten in Frage, zusätzlich auch Oxo und Thioxo. Suitable substituents for a substituted heterocyclic radical are the substituents mentioned below, and additionally also oxo and thioxo. Die Oxogruppe als Substituent an einem Ring-C-Atom bedeutet dann beispielsweise eine Carbonylgruppe im heterocyclischen Ring. The oxo group as a substituent on a ring carbon atom, then for example, a carbonyl group in the heterocyclic ring. Dadurch sind vorzugsweise auch Lactone und Lactame umfasst. Thereby, preferably lactones and lactams comprises. Die Oxogruppe kann auch an den Heteroringatomen, die in verschiedenen Oxidationsstufen existieren können, zB bei N und S, auftreten und bilden dann beispielsweise die divalenten Gruppen N(O) , S(O) (auch kurz SO) und S(O)2 (auch kurz SO2) im heterocyclischen Ring. The oxo group can also occur on the hetero ring atoms which can exist in different oxidation states, for example at N and S. and then form, for example, divalent groups N (O), S (O) (also abbreviated SO) and S (O) 2 ( also briefly SO2) in the heterocyclic ring. Im Fall von -N(O)- und -S(0)-Gruppen sind jeweils beide Enantiomere umfasst. In the case of -N (O) - and -S (0) groups in each case both enantiomers are included.

Erfindungsgemäß steht der Ausdruck„Heteroaryl" für heteroaromatische According to the invention, the term "heteroaryl" heteroaromatic

Verbindungen, dh vollständig ungesättigte aromatische heterocyclische Compounds, ie fully unsaturated aromatic heterocyclic

Verbindungen, vorzugsweise für 5- bis 7-gliedrige Ringe mit 1 bis 4, vorzugsweise 1 oder 2 gleichen oder verschiedenen Heteroatomen, vorzugsweise 0, S oder N. Compounds, preferably 5- to 7-membered rings with 1 to 4, preferably 1 or 2 identical or different heteroatoms, preferably 0, S or N.

Erfindungsgemäße Heteroaryle sind beispielsweise 1 H-Pyrrol-1 -yl; Inventive heteroaryls are for example 1 H-pyrrol-1-yl; 1 H-Pyrrol-2-yl; 1 H-pyrrol-2-yl; 1 H-Pyrrol-3-yl; 1 H-pyrrole-3-yl; Furan-2-yl; Furan-2-yl; Furan-3-yl; Furan-3-yl; Thien-2-yl; Thien-2-yl; Thien-3-yl, 1 H-lmidazol-1 -yl; Thien-3-yl, 1 H-imidazol-1-yl; 1 H- lmidazol-2-yl; 1 H- imidazol-2-yl; 1 H-lmidazol-4-yl; 1 H-imidazole-4-yl; 1 H-lmidazol-5-yl; 1 H-imidazol-5-yl; 1 H-Pyrazol-1 -yl; 1 H-pyrazol-1-yl; 1 H-Pyrazol-3-yl; 1 H-pyrazol-3-yl; 1 H-Pyrazol-4-yl; 1 H-pyrazol-4-yl; 1 H-Pyrazol-5-yl, 1 H-1 ,2,3-Triazol-1 -yl, 1 H-1 ,2,3-Triazol-4-yl, 1 H- 1 ,2,3-Triazol-5-yl, 2H-1 ,2,3-Triazol-2-yl, 2H-1 ,2,3-Triazol-4-yl, 1 H-1 ,2,4-Triazol-1 -yl, 1 H-1 ,2,4-Triazol-3-yl, 4H-1 ,2,4-Triazol-4-yl, 1 ,2,4-Oxadiazol-3-yl, 1 ,2,4-Oxadiazol-5- yl, 1 ,3,4-Oxadiazol-2-yl, 1 ,2,3-Oxadiazol-4-yl, 1 ,2,3-Oxadiazol-5-yl, 1 ,2,5-Oxadiazol- 1 H-pyrazol-5-yl, 1 H-1, 2,3-triazol-1-yl, 1 H-1, 2,3-triazol-4-yl, 1 H- 1, 2,3-triazole 5-yl, 2H-1, 2,3-triazol-2-yl, 2H-1, 2,3-triazol-4-yl, 1 H-1, 2,4-triazol-1-yl, 1 H- 1, 2,4-triazol-3-yl, 4H-1, 2,4-triazol-4-yl, 1, 2,4-oxadiazol-3-yl, 1, 2,4-oxadiazol-5-yl, 1, 3,4-oxadiazol-2-yl, 1, 2,3-oxadiazol-4-yl, 1, 2,3-oxadiazol-5-yl, 1, 2,5-oxadiazole

3- yl, Azepinyl, Pyridin-2-yl, Pyridin-3-yl, Pyridin-4-yl, Pyrazin-2-yl, Pyrazin-3-yl, Pyrimidin-2-yl, Pyrimidin-4-yl, Pyrimidin-5-yl, Pyridazin-3-yl, Pyridazin-4-yl, 1 ,3,5- 3- yl, azepinyl, pyridin-2-yl, pyridin-3-yl, pyridin-4-yl, pyrazin-2-yl, pyrazin-3-yl, pyrimidin-2-yl, pyrimidin-4-yl, pyrimidine 5-yl, pyridazin-3-yl, pyridazin-4-yl, 1, 3,5-

Triazin-2-yl, 1 ,2,4-Triazin-3-yl, 1 ,2,4-Triazin-5-yl, 1 ,2,4-Triazin-6-yl, 1 ,2,3-Triazin-4-yl, 1 ,2,3-Triazin-5-yl, 1 ,2,4-, 1 ,3,2-, 1 ,3,6- und 1 ,2,6-Oxazinyl, lsoxazol-3-yl, lsoxazol-4- yl, lsoxazol-5-yl, 1 ,3-Oxazol-2-yl, 1 ,3-Oxazol-4-yl, 1 ,3-Oxazol-5-yl, lsothiazol-3-yl, lsothiazol-4-yl, lsothiazol-5-yl, 1 ,3-Thiazol-2-yl, 1 ,3-Thiazol-4-yl, 1 ,3-Thiazol-5-yl, Oxepinyl, Thiepinyl, 1 ,2,4-Triazolonyl und 1 ,2,4-Diazepinyl, 2H-1 ,2,3,4-Tetrazol-5-yl, 1 H-1 ,2,3,4-Tetrazol-5-yl, 1 ,2,3,4-Oxatriazol-5-yl, 1 ,2,3,4-Thiatriazol-5-yl, 1 ,2,3,5- Oxatriazol-4-yl, 1 ,2,3,5-Thiatriazol-4-yl. Triazin-2-yl, 1, 2,4-triazine-3-yl, 1, 2,4-triazin-5-yl, 1, 2,4-triazine-6-yl, 1, 2,3-triazine 4-yl, 1, 2,3-triazin-5-yl, 1, 2,4-, 1, 3,2-, 1, 3,6- and 1, 2,6-oxazinyl, isoxazole-3-yl , isoxazole-4-yl, isoxazole-5-yl, 1, 3-oxazol-2-yl, 1, 3-oxazol-4-yl, 1, 3-oxazol-5-yl, isothiazol-3-yl, isothiazol -4-yl, isothiazol-5-yl, 1, 3-thiazol-2-yl, 1, 3-thiazol-4-yl, 1, 3-thiazol-5-yl, oxepinyl, thiepinyl, 1, 2.4 -Triazolonyl and 1, 2,4-diazepinyl, 2H-1, 2,3,4-tetrazol-5-yl, 1 H-1, 2,3,4-tetrazol-5-yl, 1, 2,3, 4-oxatriazole-5-yl, 1, 2,3,4-thiatriazole-5-yl, 1, 2,3,5-oxatriazole-4-yl, 1, 2,3,5-thiatriazole-4-yl. Die erfindungsgemäßen Heteroarylgruppen können ferner mit einem oder mehreren, gleichen oder verschiedenen Resten substituiert sein. The heteroaryl groups of the invention may further be substituted with one or more, identical or different radicals. Sind zwei benachbarte Kohlenstoffatome Bestandteil eines weiteren aromatischen Rings, so handelt es sich um annellierte heteroaromatische Systeme, wie benzokondensierte oder mehrfach annellierte Heteroaromaten. Are two adjacent carbon atoms of a component of another aromatic ring, it is fused heteroaromatic systems such as benzofused or multiple fused heteroaromatic.

Bevorzugt sind beispielsweise Chinoline (z. B. Chinolin-2-yl, Chinolin-3-yl, Chinolin- Preferred quinolines example are (z. B. quinoline-2-yl, quinolin-3-yl, quinoline

4- yl, Chinolin-5-yl, Chinolin-6-yl, Chinolin-7-yl, Chinolin-8-yl); 4- yl, quinolin-5-yl, quinolin-6-yl, quinolin-7-yl, quinoline-8-yl); Isochinoline (z. B. Isoquinolines (z. B.

lsochinolin-1 -yl, lsochinolin-3-yl, lsochinolin-4-yl, lsochinolin-5-yl, lsochinolin-6-yl, lsochinolin-7-yl, lsochinolin-8-yl); isoquinoline-1-yl, isoquinoline-3-yl, isoquinoline-4-yl, isoquinoline-5-yl, isoquinoline-6-yl, isoquinoline-7-yl, isoquinoline-8-yl); Chinoxalin; Quinoxaline; Chinazolin; Quinazoline; Cinnolin; Cinnoline; 1 ,5-Naphthyridin; 1, 5-naphthyridine; 1 ,6-Naphthyridin; 1, 6-naphthyridine; 1 ,7-Naphthyridin; 1, 7-naphthyridine; 1 ,8-Naphthyridin; 1, 8-naphthyridine; 2,6-Naphthyridin; 2,6-naphthyridine; 2,7- Naphthyridin; 2,7-naphthyridine; Phthalazin; Phthalazine; Pyridopyrazine; Pyridopyrazine; Pyridopyrimidine; Pyridopyrimidines; Pyridopyridazine; Pyridopyridazine; Pteridine; Pteridines; Pyrimidopyrimidine. Pyrimidopyrimidine. Beispiele für Heteroaryl sind auch 5- oder 6-gliedrige benzokondensierte Ringe aus der Gruppe 1 H-lndol-1 -yl, 1 H-lndol-2-yl, 1 H-lndol-3-yl, 1 H-lndol-4-yl, 1 H-lndol-5-yl, 1 H-lndol-6-yl, 1 H-lndol-7-yl, 1 -Benzofuran-2-yl, 1 - Benzofuran-3-yl, 1 -Benzofuran-4-yl, 1 -Benzofuran-5-yl, 1 -Benzofuran-6-yl, 1 - Benzofuran-7-yl, 1 -Benzothiophen-2-yl, 1 -Benzothiophen-3-yl, 1 -Benzothiophen-4-yl, 1 -Benzothiophen-5-yl, 1 -Benzothiophen-6-yl, 1 -Benzothiophen-7-yl, 1 H-lndazol-1 -yl, 1 H-lndazol-3-yl, 1 H-lndazol-4-yl, 1 H-lndazol-5-yl, 1 H-lndazol-6-yl, 1 H-lndazol-7-yl, 2H-lndazol-2-yl, 2H-lndazol-3-yl, 2H-lndazol-4-yl, 2H-lndazol-5-yl, 2H-lndazol-6-yl, 2H-lndazol-7-yl, 2H-lsoindol-2-yl, 2H-lsoindol-1 -yl, 2H-lsoindol-3-yl, 2H-lsoindol-4-yl, 2H-lsoindol-5-yl, 2H-lsoindol-6-yl; Examples of heteroaryl are 5- or 6-membered benzo-fused rings from the group 1H-indole-1-yl, 1H-indole-2-yl, 1H-indole-3-yl, 1H-indole-4 yl, 1 H-indole-5-yl, 1 H-indole-6-yl, 1 H-indole-7-yl, 1 -benzofuran-2-yl, 1 - benzofuran-3-yl, 1 -benzofuran-4 -yl, 1 -benzofuran-5-yl, 1 -benzofuran-6-yl, 1 - benzofuran-7-yl, 1 -benzothiophene-2-yl, 1 -benzothiophene-3-yl, 1 -benzothiophene-4-yl , 1 -benzothiophene-5-yl, 1 -benzothiophene-6-yl, 1 -benzothiophene-7-yl, 1 H-lndazol-1-yl, 1 H-lndazol-3-yl, 1 H-lndazol-4- yl, 1 H-lndazol-5-yl, 1 H-lndazol-6-yl, 1 H-lndazol-7-yl, 2H-lndazol-2-yl, 2H-lndazol-3-yl, 2H-lndazol-4 -yl, 2H-lndazol-5-yl, 2H-lndazol-6-yl, 2H-lndazol-7-yl, 2H-isoindole-2-yl, 2H-isoindole-1-yl, 2H-isoindole-3-yl , 2H-isoindole-4-yl, 2H-isoindole-5-yl, 2H-isoindole-6-yl; 2H-lsoindol-7-yl, 1 H-Benzimidazol-1 -yl, 1 H- 2H-isoindole-7-yl, 1 H-benzimidazol-1-yl, 1 H-

Benzimidazol-2-yl, 1 H-Benzimidazol-4-yl, 1 H-Benzimidazol-5-yl, 1 H-Benzimidazol-6- yl, 1 H-Benzimidazol-7-yl, 1 ,3-Benzoxazol-2-yl, 1 ,3-Benzoxazol-4-yl, 1 ,3-Benzoxazol- 5-yl, 1 ,3-Benzoxazol-6-yl, 1 ,3-Benzoxazol-7-yl, 1 ,3-Benzthiazol-2-yl, 1 ,3-Benzthiazol- 4-yl, 1 ,3-Benzthiazol-5-yl, 1 ,3-Benzthiazol-6-yl, 1 ,3-Benzthiazol-7-yl, 1 ,2- Benzisoxazol-3-yl, 1 ,2-Benzisoxazol-4-yl, 1 ,2-Benzisoxazol-5-yl, 1 ,2-Benzisoxazol-6- yl, 1 ,2-Benzisoxazol-7-yl, 1 ,2-Benzisothiazol-3-yl, 1 ,2-Benzisothiazol-4-yl, 1 ,2- Benzisothiazol-5-yl, 1 ,2-Benzisothiazol-6-yl, 1 ,2-Benzisothiazol-7-yl. Benzimidazol-2-yl, 1 H-benzimidazol-4-yl, 1 H-benzimidazol-5-yl, 1 H-benzimidazol-6-yl, 1 H-benzimidazol-7-yl, 1, 3-benzoxazol-2- yl, 1, 3-benzoxazole-4-yl, 1, 3-benzoxazole-5-yl, 1, 3-benzoxazol-6-yl, 1, 3-benzoxazole-7-yl, 1, 3-benzothiazol-2- yl, 1, 3-benzothiazole-4-yl, 1, 3-benzothiazol-5-yl, 1, 3-benzothiazol-6-yl, 1, 3-benzothiazol-7-yl, 1, 2- benzisoxazole-3- yl, 1, 2-benzisoxazol-4-yl, 1, 2-benzisoxazol-5-yl, 1, 2-benzisoxazol-6- yl, 1, 2-benzisoxazole-7-yl, 1, 2-benzisothiazol-3- yl, 1, 2-benzisothiazol-4-yl, 1, 2- benzisothiazol-5-yl, 1, 2-benzisothiazol-6-yl, 1, 2-benzisothiazol-7-yl.

Die Bezeichnung "Halogen" bedeutet beispielsweise Fluor, Chlor, Brom oder lod. The term "halogen" means, for example, fluorine, chlorine, bromine or iodine. Wird die Bezeichnung für einen Rest verwendet, dann bedeutet "Halogen" Is the name given to a radical used, it means "halogen"

beispielsweise ein Fluor-, Chlor-, Brom- oder lodatom. for example, a fluorine, chlorine, bromine or iodine atom.

Erfindungsgemäß bedeutet„Alkyl" einen geradkettigen oder verzweigten According to the invention "alkyl" means a straight or branched

offenkettigen, gesättigten Kohlenwasserstoffrest, der gegebenenfalls ein- oder mehrfach substituiert ist. open-chain, saturated hydrocarbon radical which is optionally mono- or polysubstituted. Bevorzugte Substituenten sind Halogenatome, Alkoxy-, Haloalkoxy-, Cyano-, Alkylthio, Haloalkylthio-, Amino- oder Nitrogruppen, besonders bevorzugt sind Methoxy, Methyl, Fluoralkyl, Cyano, Nitro, Fluor, Chlor, Brom oder lod. Preferred substituents are halogen atoms, alkoxy, haloalkoxy, cyano, alkylthio, Haloalkylthio-, amino or nitro groups, especially preferred are methoxy, methyl, fluoroalkyl, cyano, nitro, fluorine, chlorine, bromine or iodine. „Haloalkyl", ,,-alkenyl" und ,,-alkinyl" bedeuten durch gleiche oder verschiedene Halogenatome, teilweise oder vollständig substituiertes Alkyl, Alkenyl bzw. Alkinyl, zB Monohaloalkyl (= Monohalogenalkyl) wie z. B. CH2CH2CI, CH 2 CH 2 Br, CHCICH3, ChbCI, CH 2 F; Perhaloalkyl wie z. B. CCI 3 , CCIF 2 , CFCl2,CF 2 CCIF 2 , CF2CCIFCF3; Polyhaloalkyl wie z. B. CH2CHFCI, CF2CCIFH, CF 2 CBrFH, CH2CF3; Der Begriff Perhaloalkyl umfasst dabei auch den Begriff Perfluoralkyl. Haloalkoxy ist zB OCF 3 , OCHF2, OCH 2 F, OCF2CF3, OCH2CF3 und OCH2CH2CI; Entsprechendes gilt für Haloalkenyl und andere durch Halogen substituierten Reste. "Haloalkyl", ,, - alkenyl "and ,, - alkynyl" mean by identical or different halogen atoms, partially or completely substituted alkyl, alkenyl or alkynyl, for example monohaloalkyl (= monohaloalkyl) such as CH2CH2CI, CH 2 CH 2. Br, CHCICH3, ChbCI, CH 2 F; perhaloalkyl such as CCI 3, CCIF 2, CFCl2, CF 2 CCIF 2, CF2CCIFCF3;. polyhaloalkyl such as CH2CHFCI, CF2CCIFH, CF 2 CBrFH, CH2CF3;. The term perhaloalkyl . this also includes the term perfluoroalkyl haloalkoxy is for example OCF 3, OCHF2, OCH 2 F, OCF2CF3, OCH2CF3 and OCH2CH2CI; same applies to haloalkenyl and other halogen-substituted radicals.

Der hier beispielhaft genannte Ausdruck "(Ci-C 4 )-Alkyl" bedeutet eine The example referred to herein, the term "(Ci-C4) alkyl" means a

Kurzschreibweise für geradkettiges oder verzweigtes Alkyl mit einem bis 4 Shorthand notation for straight-chain or branched alkyl having from one to 4

Kohlenstoffatomen entsprechend der Bereichsangabe für C-Atome, dh umfasst die Reste Methyl, Ethyl, 1 -Propyl, 2-Propyl, 1 -Butyl, 2-Butyl, 2-Methylpropyl oder tert- Butyl. Carbon atoms corresponding to the range specification for C-atoms, ie comprises the radicals methyl, ethyl, 1 -propyl, 2-propyl, 1-butyl, 2-butyl, 2-methylpropyl or tert-butyl. Allgemeine Alkylreste mit einem größeren angegebenen Bereich von C- Atomen, z. B. "(Ci-C6)-Alkyl", umfassen entsprechend auch geradkettige oder verzweigte Alkylreste mit einer größeren Zahl von C-Atomen, dh gemäß Beispiel auch die Alkylreste mit 5 und 6 C-Atomen. General alkyl radicals having a wider stated range of carbon atoms, eg. B. "(Ci-C6) -alkyl", corresponding to include straight-chain or branched alkyl radicals having a larger number of carbon atoms, that is, according to Example, the alkyl radicals having 5 and 6 carbon atoms.

Wenn nicht speziell angegeben, sind bei den Kohlenwasserstoffresten wie Alkyl-, Alkenyl- und Alkinylresten, auch in zusammengesetzten Resten, die niederen Kohlenstoffgerüste, zB mit 1 bis 6 C-Atomen bzw. bei ungesättigten Gruppen mit 2 bis 6 C-Atomen, bevorzugt. Unless specifically indicated, are in the hydrocarbon radicals such as alkyl, alkenyl and alkynyl, also in composite radicals, the lower carbon skeletons, for example having 1 to 6 carbon atoms or, in unsaturated groups with 2 to 6 carbon atoms are preferred. Alkylreste, auch in den zusammengesetzten Resten wie Alkoxy, Haloalkyl usw., bedeuten zB Methyl, Ethyl, n- oder i-Propyl, n-, i-, t- oder 2-Butyl, Pentyle, Hexyle, wie n-Hexyl, i-Hexyl und 1 ,3-Dimethylbutyl, Heptyle, wie n-Heptyl, 1 -Methylhexyl und 1 ,4-Dimethylpentyl; Alkyl radicals, including in composite radicals such as alkoxy, haloalkyl etc., are, for example, methyl, ethyl, n- or i-propyl, n-, i-, t- or 2-butyl, pentyls, hexyls, such as n-hexyl, i -hexyl and 1, 3-dimethylbutyl, heptyls, such as n-heptyl, 1 -Methylhexyl and 1, 4-dimethylpentyl; Alkenyl- und Alkinylreste haben die Bedeutung der den Alkylresten entsprechenden möglichen ungesättigten Reste, wobei mindestens eine Doppelbindung bzw. Dreifachbindung enthalten ist. Alkenyl and alkynyl radicals have the meaning of the possible unsaturated radicals corresponding to the alkyl radicals, at least one double bond or triple bond is included.

Bevorzugt sind Reste mit einer Doppelbindung bzw. Dreifachbindung. Preferred radicals containing one double bond or triple bond.

Der Begriff„Alkenyl" schließt insbesondere auch geradkettige oder verzweigte offenkettige Kohlenwasserstoffreste mit mehr als einer Doppelbindung ein, wie 1 ,3- Butadienyl und 1 ,4-Pentadienyl, aber auch Allenyl- oder Kumulenyl-reste mit einer bzw. mehreren kumulierten Doppelbindungen, wie beispielsweise Allenyl (1 ,2- Propadienyl), 1 ,2-Butadienyl und 1 ,2,3-Pentatrienyl. Alkenyl bedeutet zB Vinyl, welches ggf. durch weitere Alkylreste substituiert sein kann, zB Prop-1 -en-1 -yl, But- The term "alkenyl" includes in particular linear or branched-chain hydrocarbon radicals with more than one double bond, such as 1, 3-butadienyl and 1, 4-pentadienyl, but also allenyl or cumulenyl radicals having one or more cumulated double bonds, for example allenyl (1, 2 propadienyl), 1, 2-butadienyl and 1, 2,3-Pentatrienyl. alkenyl as vinyl, which can be substituted by further alkyl groups possibly, for example, prop-1 -en-1-yl, butter

1 - en-l -yl, Allyl, 1 -Methyl-prop-2-en-1 -yl, 2-Methyl-prop-2-en-1 -yl, But-2-en-1 -yl, 1 - Methyl-but-3-en-1 -yl und 1 -Methyl-but-2-en-1 -yl, 2-Methyl-prop-1 -en-1 -yl, 1 - en-l-yl, allyl, 1-methyl-prop-2-en-1-yl, 2-prop-2-en-1-yl methyl, but-2-en-1 -yl, 1 - methyl-but-3-en-1-yl and 1-methyl-but-2-en-1-yl, 2-methyl-prop-1 -en-1 -yl,

1 -Methylprop-1 -en-1 -yl, 1 -Methyl prop-2-en-1 -yl, 2-Methyl-prop-2-en-1 -yl, 1 -Methylprop-1 -en-1 -yl, 1 -methyl prop-2-en-1-yl, 2-methyl-prop-2-en-1-yl,

But-2-en-1 -yl, But-3-en-1 -yl, 1 -Methyl-but-3-en-1 -yl oder 1 -Methyl-but-2-en-1 -yl, Pentenyl, 2-Methylpentenyl oder Hexenyl. But-2-en-1-yl, but-3-en-1 -yl, 1 -methyl-but-3-en-1-yl or 1-methyl-but-2-en-1-yl, pentenyl, 2-methylpentenyl or hexenyl.

Der Begriff„Alkinyl" schließt insbesondere auch geradkettige oder verzweigte offenkettige Kohlenwasserstoffreste mit mehr als einer Dreifachbindung oder auch mit einer oder mehreren Dreifachbindungen und einer oder mehreren The term "alkynyl" includes in particular straight-chain or branched-chain hydrocarbon radicals with more than one triple bond or having one or more triple bonds and one or more

Doppelbindungen ein, wie beispielsweise 1 ,3-Butatrienyl bzw. 3-Penten-1 -in-1 -yl. Double bonds, such as 1, 3-Butatrienyl or 3-penten-1-in-1-yl. (C2-C6)-Alkinyl bedeutet beispielsweise Ethinyl, Propargyl, 1 -Methyl-prop-2-in-1 -yl, (C2-C6) alkynyl is, for example ethynyl, propargyl, 1-methyl-prop-2-in-1-yl,

2- Butinyl, 2-Pentinyl oder 2-Hexinyl, vorzugsweise Propargyl, But-2-in-1 -yl, 2- butynyl, 2-pentynyl or 2-hexynyl, preferably propargyl, but-2-in-1-yl,

But-3-in-1 -yl oder 1 -Methyl-but-3-in-1 -yl. But-3-in-1-yl or 1-methyl-but-3-in-1-yl.

Der Begriff„Cycloalkyl" bedeutet ein carbocyclisches, gesättigtes Ringsystem mit vorzugsweise 3-8 Ring-C-Atomen, zB Cyclopropyl, Cyclobutyl, Cyclopentyl oder Cyclohexyl. Im Falle von gegebenenfalls substituiertem Cycloalkyl werden cyclische Systeme mit Substituenten umfasst, wobei auch Substituenten mit einer The term "cycloalkyl" is a carbocyclic saturated ring system having preferably 3-8 ring carbon atoms, for example cyclopropyl, cyclobutyl, cyclopentyl or cyclohexyl. In the case of optionally substituted cycloalkyl, cyclic systems with substituents are included, where also substituents having a

Doppelbindung am Cycloalkylrest, z. B. eine Alkylidengruppe wie Methyliden, umfasst sind. Double bond on the cycloalkyl radical, z. B. are an alkylidene group such as methylidene. Im Falle von gegebenenfalls substituiertem Cycloalkyl werden auch mehrcyclische aliphatische Systeme umfaßt, wie beispielsweise Bicyclo[1 .1 .0]butan- 1 -yl, Bicyclo[1 .1 .0]butan-2-yl, Bicyclo[2.1 .0]pentan-1 -yl, Bicyclo[2.1 .0]pentan-2-yl, Bicyclo[2.1 .0]pentan-5-yl, Bicyclo[2.2.1 ]hept-2-yl (Norbornyl), Bicyclo[2.2.2]octan-2- yl, Adamantan-1 -yl und Adamantan-2-yl. In the case of optionally substituted cycloalkyl, polycyclic aliphatic systems are covered, such as bicyclo [1 .1 .0] butane-1-yl, bicyclo [1 .1 .0] butane-2-yl, bicyclo [2.1 .0] pentane -1 -yl, bicyclo [2.1 .0] pentan-2-yl, bicyclo [2.1 .0] pentan-5-yl, bicyclo [2.2.1] hept-2-yl (norbornyl), bicyclo [2.2.2] octan-2-yl, adamantan-1-yl and adamantan-2-yl. Der Ausdruck "(C3-C7)-Cycloalkyl" bedeutet eine Kurzschreibweise für Cycloalkyl mit drei bis 7 Kohlenstoffatomen entsprechend der Bereichsangabe für C-Atome. The term "(C3-C7) cycloalkyl" is an abbreviated notation for cycloalkyl having three to seven carbon atoms corresponding to the range specification for carbon atoms.

Im Falle von substituiertem Cycloalkyl werden auch spirocyclische aliphatische Systeme umfaßt, wie beispielsweise Spiro[2.2]pent-1 -yl, Spiro[2.3]hex-1 -yl, In case of substituted cycloalkyl also spirocyclic aliphatic systems are covered, such as spiro [2.2] pent-1-yl, spiro [2.3] hex-1-yl,

Spiro[2.3]hex-4-yl, 3-Spiro[2.3]hex-5-yl. Spiro [2.3] hex-4-yl, 3-spiro [2.3] hex-5-yl. „Cycloalkenyl" bedeutet ein carbocyclisches, nicht aromatisches, partiell ungesättigtes Ringsystem mit vorzugsweise 4-8 C-Atomen, zB 1 -Cyclobutenyl, 2- Cyclobutenyl, 1 -Cyclopentenyl, 2-Cyclopentenyl, 3-Cyclopentenyl, oder 1 - Cyclohexenyl, 2-Cyclohexenyl, 3-Cyclohexenyl, 1 ,3-Cyclohexadienyl oder 1 ,4- Cyclohexadienyl, wobei auch Substituenten mit einer Doppelbindung am "Cycloalkenyl" means a carbocyclic non-aromatic partially unsaturated ring system having preferably 4-8 carbon atoms, for example 1 -Cyclobutenyl, 2- cyclobutenyl, 1 -Cyclopentenyl, 2-cyclopentenyl, 3-cyclopentenyl, or 1 - cyclohexenyl, 2- cyclohexenyl, 3-cyclohexenyl, 1, 3-cyclohexadienyl or 1, 4-cyclohexadienyl, wherein also substituents having a double bond at

Cycloalkenylrest, z. B. eine Alkylidengruppe wie Methyliden, umfasst sind. Cycloalkenyl, z. B. are an alkylidene group such as methylidene. Im Falle von gegebenenfalls substituiertem Cycloalkenyl gelten die Erläuterungen für substituiertes Cycloalkyl entsprechend. In the case of optionally substituted cycloalkenyl, the explanations for substituted cycloalkyl apply correspondingly. Der Begriff„Alkyliden", z. B. auch in der Form (Ci-Cio)-Alkyliden, bedeutet den Rest eines geradkettigen oder verzweigten offenkettigen Kohlenwasserstoffrests, der über eine Zweifachbindung gebunden ist. Als Bindungsstelle für Alkyliden kommen naturgemäß nur Positionen am Grundkörper in Frage, an denen zwei H-Atome durch die Doppelbindung ersetzt werden können; Reste sind z. B. =CH2, =CH-CH3, =C(CH 3 )-CH 3 , =C(CH 3 )-C 2 H5 oder =C(C 2 H5)-C2H 5 . Cycloalkyliden bedeutet ein carbocyclischer Rest, der über eine Zweifachbindung gebunden ist. The term "alkylidene" z. B. also in the form of (Ci-Cio) alkylidene, is the radical of a linear or branched open-chain hydrocarbon group, which is attached via a double bond. As a binding site for alkylidene come naturally only positions on the main body in question, at which two H atoms may be replaced by the double bond; radicals are, for example, = CH2, = CH-CH3, = C (CH 3) -CH 3, = C (CH 3) -C 2 H5 or. = C (C 2 H5) -C2H fifth cycloalkylidene means a carbocyclic radical which is bonded via a double bond.

Die Verbindungen der allgemeinen Formel (I) können je nach Art und Verknüpfung der Substituenten als Stereoisomere vorliegen. The compounds of general formula (I) may exist as stereoisomers depending on the nature and linkage of the substituents. Die durch ihre spezifische Raumform definierten möglichen Stereoisomere, wie Enantiomere, Diastereomere, Z- und E- Isomere sind alle von der Formel (I) umfasst. Defined by their specific spatial form possible stereoisomers, such as enantiomers, diastereomers, Z and E isomers, are all encompassed by the formula (I). Sind beispielsweise eine oder mehrere Alkenylgruppen vorhanden, so können Diastereomere (Z- und E-Isomere) auftreten. For example, if one or more alkenyl groups are present, diastereomers can (Z and E isomers) may occur. Sind beispielsweise ein oder mehrere asymmetrische Kohlenstoffatome vorhanden, so können Enantiomere und Diastereomere auftreten. For example, if one or more asymmetric carbon atoms are present, enantiomers and diastereomers may occur. Stereoisomere lassen sich aus den bei der Herstellung anfallenden Gemischen nach üblichen Trennmethoden erhalten. Stereoisomers can be obtained from the obtained in the preparation by customary separation methods. Die chromatographische Trennung kann sowohl im analytischen Maßstab zur Feststellung des Enantiomerenüberschusses bzw. des The chromatographic separation can be both analytical scale to determine the enantiomeric excess and the

Diastereomerenüberschusses, wie auch im präparativen Maßstab zur Herstellung von Prüfmustern für die biologische Ausprüfung erfolgen. Diastereomeric excess as also take place on a preparative scale for the preparation of samples for biological testing was. Ebenso können Can also

Stereoisomere durch Einsatz stereoselektiver Reaktionen unter Verwendung optisch aktiver Ausgangs- und/oder Hilfsstoffe selektiv hergestellt werden. Stereoisomers are selectively prepared by employing stereoselective reactions using optically active starting materials and / or adjuvants. Die Erfindung betrifft somit auch alle Stereoisomeren, die von der allgemeinen Formel (I) umfasst, jedoch nicht mit ihrer spezifischen Stereoform angegeben sind, sowie deren The invention also relates to all stereoisomers embraced by the general formula (I), but are not shown in their specific stereo form, as well as their

Gemische. Mixtures.

Synthese von offenkettigen Aryl-, Heteroaryl und Benzylsulfonamiden mit Synthesis of open-chain aryl, heteroaryl and Benzylsulfonamiden with

substituierter Alkylseitenkette und deren Analoga. substituted alkyl side chain and their analogs.

Die erfindungsgemäßen gegebenenfalls weiter substituierten offenkettigen Aryl-, Heteroaryl- und Benzylsulfonamide der allgemeinen Formel (I) können nach bekannten Verfahren hergestellt werden (vgl. Eur J. Med. Chem. 2010, 45, 1760; Comb. Chem. & High Throughput Scr. 2009, 12, 275; Bioorg. Med. Chem. 2007, 15, 7553; EP2065370). The invention optionally further substituted open chain aryl, heteroaryl and Benzylsulfonamide of the general formula (I) can be prepared (see, Eur J. Med Chem 2010, 45 by known methods, 1760;... Comb Chem High Throughput & Scr... 2009, 12, 275; Bioorg Med Chem 2007, 15, 7553;... EP2065370). Die eingesetzten und untersuchten Syntheserouten gehen dabei von kommerziell erhältlichen oder leicht herstellbaren Aminosäurederivaten, The synthetic routes used and studied here go from commercially available or easily obtainable amino acid derivatives,

Aminoalkylnitrilvorstufen und den entsprechenden Sulfonylchloriden aus. Aminoalkylnitrilvorstufen and the corresponding sulfonyl out.

Aryl- und Heteroarylsulfonylchloridvorstufen können beispielsweise über direkte Chlorsulfonierung der entsprechenden substituierten Aromaten und Heteroaromaten (vgl. Eur J. Med. Chem. 2010, 45, 1760) oder über Diazotierung eines Amino- substituierten Aromaten oder Heteroaromaten und anschließende Chlorsulfonierung hergestellt werden (vgl. WO2005035486). Aryl and Heteroarylsulfonylchloridvorstufen can, for example, by direct chlorosulfonation of the corresponding substituted aromatics and heteroaromatics (cf. Eur. J. Med. Chem. 2010, 45, 1760) or be prepared by diazotization of an amino substituted aromatic or heteroaromatic compound and subsequent chlorosulfonation (see FIG. WO2005035486 ). Die Kupplung der entsprechenden substituierten Sulfonylchloridvorstufen mit den entsprechenden Aminosäure- und Aminoalkylnitrilderivaten mit Hilfe einer geeigneten Base (z. B. Triethylamin oder Natriumhydroxid) in einem geeigneten Lösungsmittel (z. B. Tetrahydrofuran oder Dichlormethan) liefert die erfindungsgemäßen erfindungsgemäßen gegebenenfalls weiter substituierten Aryl-, Heteroaryl- und Benzylsulfonamide (beispielsweise Subklasse l(a) in Schema 1 ). The coupling of the appropriate substituted Sulfonylchloridvorstufen with the corresponding amino acid and Aminoalkylnitrilderivaten with the aid of a suitable base (e.g., triethylamine or sodium hydroxide) in a suitable solvent (e.g., tetrahydrofuran or dichloromethane) provides the invention according to the invention optionally further substituted aryl, heteroaryl and Benzylsulfonamide (eg subclass l (a) in Scheme 1).

Substituierte N-Sulfonylaminoalkylnitrile l(b) als Subklasse der erfindungsgemäßen Aryl-, Heteroaryl und Benzylsulfonamide der allgemeinen Formel I können auch über eine Strecker-Reaktion von substituierten N-Sulfonylaldiminen mit einem geeigneten Trialkylsilylcyanid in einem geeigneter polar-aprotischen Lösungsmittel (z. B. Substituted N-Sulfonylaminoalkylnitrile l (b) as a subclass of the aryl, heteroaryl and Benzylsulfonamide of the general formula I according to the invention can also have a Strecker reaction of substituted N-Sulfonylaldiminen with a suitable trialkylsilyl cyanide in a suitable polar aprotic solvent (eg. B.

Dichlormethan, Acetonitril, Propionitril) unter Verwendung von elementarem lod (vgl. Synthesis 2009, 3467) oder unter Verwendung eines geeigneten Lanthan- binaphthylsulfonatkomplexes (vgl. Org. Lett. 2009, 1 1 , 2321 ; die Abkürzung BINSA bedeutet hier 1 , 1 '-Binaphthyl-2,2'disulfonsäure) hergestellt werden. Dichloromethane, acetonitrile, propionitrile) using elemental iodine (cf. Synthesis 2009, 3467) or using a suitable lanthanum binaphthylsulfonatkomplexes (see, Org Lett, 2009, 1 1, 2321;.... The abbreviation BINSA here means 1, 1 ' binaphthyl-2,2'disulfonsäure) are produced. Einen weiteren synthetischen Zugang zu substituierten N-Sulfonylaminoalkylnitrilen 1(b) bietet die Überführung der entsprechenden substituierten N-Sulfonylaminosäurederivate 1(a) mit Hilfe von Thionylchlorid und nachfolgend wässriger ammoniakalischer Lösung in die erfindungsgemäßen substituierten N-Sulfonylaminosäureamide 1(c) und ihre weitere Umsetzung mit Thionylchlorid unter Rückflußbedingungen (vgl. Compt. Another synthetic route to substituted N-Sulfonylaminoalkylnitrilen 1 (b) provides the transfer of the corresponding substituted N-Sulfonylaminosäurederivate 1 (a) by means of thionyl chloride, followed by aqueous ammoniacal solution in which the substituted N-Sulfonylaminosäureamide 1 (c) and their continued implementation with thionyl chloride under reflux conditions (see. Compt.

Rend. Rend. Ch. 2009, 12, 1066). Ch., 2009, 12, 1066). Es wurden damit literaturbeschriebene Synthesewege angewendet und teilweise optimiert (Schema 1 ). So have been described in the literature synthetic routes used and partially optimized (Scheme 1).

Figure imgf000075_0001

Ausgewählte detaillierte Synthesebeispiele für die erfindungsgemäßen Selected detailed synthesis examples of the invention

Verbindungen der allgemeinen Formel I sind im Folgenden aufgeführt. Compounds of general formula I are listed below. Die genannten Substanznummern entsprechen den in den Tabellen 1 bis 100 genannten Numerierungen. The substance numbers referred to satisfy the requirements stated in Tables 1 to 100 numbering. Die 1 H-NMR-, 13 C-NMR- und 19 F-NMR-spektroskopischen Daten, die für die in den nachfolgenden Abschnitten beschriebenen chemischen Beispiele angegeben sind, (400 MHz bei 1 H-NMR und 150 MHz bei 13 C-NMR und 375 MHz bei 19 F-NMR, Lösungsmittel CDCI 3 , CD 3 OD oder d 6 -DMSO, interner Standard: The 1 H-NMR, 13 C-NMR and 19 F-NMR spectroscopic data given for the chemical examples described in the following sections (400 MHz for 1 H-NMR and 150 MHz for 13 C-NMR and 375 MHz for 19 F-NMR, solvent CDCI 3, CD 3 OD or d 6 -DMSO, internal standard:

Tetramethylsilan δ = 0.00 ppm), wurden mit einem Gerät der Firma Bruker erhalten, und die bezeichneten Signale haben die nachfolgend aufgeführten Bedeutungen: br = breit(es); Tetramethylsilane δ = 0.00 ppm) were obtained on a Bruker instrument and the signals indicated have the meanings set out below: br = broad (it); s = Singulett, d = Dublett, t = Triplett, dd = Doppeldublett, ddd = Dublett eines Doppeldubletts, m = Multiplett, q = Quartett, quint = Quintett, sext = Sextett, sept = Septett, t = Triplett, dq = Doppelquartett, dt = Doppeltriplett. s = singlet, d = doublet, t = triplet, dd = double doublet, ddd = doublet of double doublets, m = multiplet, q = quartet, quint = quintet, sext = sextet, sept = septet, t = triplet, dq = double quartet, dt = double triplet. Beispiel No. Example No. 1.1 -29: Methyl-3-{[(4-bromphenyl)sulfonyl]amino}-4-methylpentanoat 1.1 -29: Methyl 3 - {[(4-bromophenyl) sulfonyl] amino} -4-methylpentanoate

Figure imgf000076_0001

4-Brombenzolsulfonylchlorid (150 mg, 0.59 mmol) wurde in Tetrahydrofuran (3 ml) und Triethylamin (0.10 ml, 0.70 mmol) unter Argon gelöst. 4-bromobenzenesulfonyl chloride (150 mg, 0:59 mmol) was dissolved in tetrahydrofuran (3 ml) and triethylamine (0.10 ml, 0.70 mmol) under argon. Nach 10 min Rühren bei Raumtemperatur wurde die Reaktionslösung auf 0 °C eingekühlt und es erfolgte die Zugabe von 3-Amino-4-methylpentanot als Hydrochloridsalz (128 mg, 0.70 mmol). After 10 min stirring at room temperature the reaction solution was cooled to 0 ° C and was followed by the addition of 3-amino-4-methylpentanot as the hydrochloride salt (128 mg, 0.70 mmol). Das resultierende Reaktionsgemisch wurde 6 h lang bei Raumtemperatur nachgerührt, danach mit Dichlormethan, Wasser und ges. The resulting reaction mixture was stirred for 6 hours at room temperature, then with dichloromethane, water and sat.

Natriumhydrogencarbonat-Lösung versetzt und die wässrigen Phasen anschließend mehrfach mit Dichlormethan extrahiert. Added sodium hydrogen carbonate solution and then extracted the aqueous phase several times with dichloromethane. Die vereinigten organischen Phasen wurden über Magnesiumsulfat getrocknet, filtriert und unter vermindertem Druck eingeengt. The combined organic phases were dried over magnesium sulfate, filtered and concentrated under reduced pressure. Durch säulenchromatographische Reinigung des Rohproduktes (Gradient By column chromatographic purification of the crude product (gradient

Ethylacetat/Heptan) wurde Methyl-3-{[(4-bromphenyl)sulfonyl]amino}-4- methylpentanoat (141 mg, 66 % der Theorie) als farbloser Feststoff erhalten. 1 H- NMR (400 MHz, d 6 -DMSO δ, ppm) 7.80 (br. d, 1 H, NH), 7.78 (d, 2H), 7.67 (d, 2H), 3.41 (m, 1 H), 3.39 (s, 3H), 2.39 (dd, 1 H), 2.16 (dd, 1 H), 1 .66 (m, 1 H), 0.74 (d, 6H). Ethyl acetate / heptane) was added methyl 3 - {[(4-bromophenyl) sulfonyl] amino} -4- methylpentanoate (141 mg, 66% of theory) was obtained as a colorless solid 1 H NMR (400 MHz, d 6 -DMSO. δ, ppm) 7.80 (br. d, 1 H, NH), 7.78 (d, 2H), 7.67 (d, 2H), 3.41 (m, 1 H), 3.39 (s, 3H), 2.39 (dd, 1 H), 2.16 (dd, 1 H), 1 .66 (m, 1 H), 0.74 (d, 6H).

Beispiel No. Example No. 1.37-106: Methyl-N-[(4-methoxyphenyl)sulfonyl]histidinat 1.37-106: Methyl-N - [(4-methoxyphenyl) sulfonyl] histidinat

Figure imgf000076_0002
4-Methoxybenzolsulfonylchlorid (100 mg, 0.48 mmol) wurde in Tetrahydrofuran (5 ml) und Triethylamin (0.09 ml, 0.63 mmol) unter Argon gelöst. 4-methoxybenzenesulfonyl chloride (100 mg, 0:48 mmol) was dissolved in tetrahydrofuran (5 ml) and triethylamine (0:09 ml, 0.63 mmol) under argon. Nach 10 min Rühren bei Raumtemperatur wurde die Reaktionslösung auf 0 °C eingekühlt und es erfolgte die Zugabe von Histidinmethylester (82 mg, 0.48 mmol). After 10 min stirring at room temperature the reaction solution was cooled to 0 ° C and was followed by the addition of histidine methyl ester (82 mg, 0:48 mmol). Das resultierende The resulting

Reaktionsgemisch wurde 6 h lang bei Raumtemperatur nachgerührt, danach mit Dichlormethan, Wasser und ges. Reaction mixture was stirred for 6 hours at room temperature, then with dichloromethane, water and sat. Natriumhydrogencarbonat-Lösung versetzt und die wässrigen Phasen anschließend mehrfach mit Dichlormethan extrahiert. Added sodium hydrogen carbonate solution and then extracted the aqueous phase several times with dichloromethane. Die vereinigten organischen Phasen wurden über Magnesiumsulfat getrocknet, filtriert und unter vermindertem Druck eingeengt. The combined organic phases were dried over magnesium sulfate, filtered and concentrated under reduced pressure. Durch säulenchromatographische By column

Reinigung des Rohproduktes (Gradient Ethylacetat/Heptan) wurde Methyl-N-[(4- methoxyphenyl)sulfonyl]histidinat (1 14 mg, 34 % der Theorie) als farbloser Feststoff erhalten. 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 9.21 (br. s, 1 H, NH), 8.80 (s, 1 H), 8.36 (br. d, 1 H, NH), 7.58 (d, 2H), 7.29 (s, 1 H), 7.06 (d, 2H), 4.12 (m, 1 H), 3.84 (s, 3H), 3.75 (s, 3H), 3.02 (dd, 1 H), 2.86 (dd, 1 H). Purification of the crude product (gradient ethyl acetate / heptane) was added methyl-N - [(4-methoxyphenyl) sulfonyl] histidinat (1 14 mg, 34% of theory) was obtained as a colorless solid 1 H-NMR (400 MHz, d 6 -DMSO. δ, ppm) 9.21 (br. s, 1 H, NH), 8.80 (s, 1 H), 8:36 (br. d, 1 H, NH), 7:58 (d, 2H), 7.29 (s, 1 H) , 7:06 (d, 2H), 4.12 (m, 1 H), 3.84 (s, 3H), 3.75 (s, 3H), 3:02 (dd, 1 H), 2.86 (dd, 1 H).

In Analogie zu oben angeführten Herstellungsbeispielen und unter Berücksichtigung der allgemeinen Angaben zur Herstellung von Verbindungen der Formel (I) erhält man folgende Verbindungen, mit den in nachfolgender Tabelle spezifisch genannten Grundkörpern 1.1 - 1.1 12 In analogy to above production examples and taking into account the general preparation of compounds of formula (I), the following compounds, with the specifically mentioned in the table below Primitives 1.1 - 1.1 12

Figure imgf000077_0001

Figure imgf000078_0001

Figure imgf000079_0001
Figure imgf000080_0001

1.61 1.62 1.63 1.64 1.61 1.62 1.63 1.64

Figure imgf000080_0003

Figure imgf000080_0004
Figure imgf000080_0002

Figure imgf000081_0001
Figure imgf000082_0001

Tabelle 1 - mit Grundkörper 1.1 und den genannten Resten Q: Table 1 - with base 1.1 and said radicals Q:

Figure imgf000083_0001
Figure imgf000083_0002

Figure imgf000083_0003

Tabelle 2 - mit Grundkörper 1.2 und den genannten Resten Q: Table 2 - with base 1.2 and said radicals Q:

Figure imgf000084_0001

Figure imgf000084_0002

Figure imgf000084_0003

Figure imgf000084_0004

Tabelle 3 - mit Grundkörper 1.3 und den genannten Resten Q: Table 3 - with base 1.3 and said radicals Q:

Figure imgf000085_0001

Figure imgf000085_0002

Figure imgf000085_0003

Figure imgf000085_0004

Tabelle 4 - mit Grundkörper 1.4 und den genannten Resten Q: Table 4 - with base 1.4 and said radicals Q:

Figure imgf000086_0001

Figure imgf000086_0002

Figure imgf000086_0003

Figure imgf000086_0004

Tabelle 5 - mit Grundkörper 1.5 und den genannten Resten Q: Table 5 - with base 1.5 and said radicals Q:

Figure imgf000087_0001

Figure imgf000087_0002

Figure imgf000087_0003

Figure imgf000087_0004

Tabelle 6 - mit Grundkörper 1.6 und den genannten Resten Q: Table 6 - with base 1.6 and said radicals Q:

Figure imgf000088_0001

Figure imgf000088_0002

Figure imgf000088_0003

Figure imgf000088_0004

Tabelle 7 - mit Grundkörper 1.7 und den genannten Resten Q: Table 7 - with base 1.7 and said radicals Q:

Figure imgf000089_0001

Figure imgf000089_0002

Figure imgf000089_0003

Figure imgf000089_0004

Tabelle 8 - mit Grundkörper 1.8 und den genannten Resten Q: Table 8 - with base 1.8 and said radicals Q:

Figure imgf000090_0001

Figure imgf000090_0002

Figure imgf000090_0003

Figure imgf000090_0004

Tabelle 9 - mit Grundkörper 1.9 und den genannten Resten Q: Table 9 - with base 1.9 and said radicals Q:

Figure imgf000091_0001

Figure imgf000091_0002

Figure imgf000091_0003

Figure imgf000091_0004

Tabelle 10 - mit Grundkörper 1.10 und den genannten Resten Q: Table 10 - with base 1:10 and said radicals Q:

Figure imgf000092_0001

Figure imgf000092_0002

Figure imgf000092_0003

Figure imgf000092_0004

Tabelle 11 - mit Grundkörper 1.11 und den genannten Resten Q: Table 11 - with base 1.11 and said radicals Q:

Figure imgf000093_0001

Figure imgf000093_0002

Figure imgf000093_0003

Figure imgf000093_0004

Tabelle 12 - mit Grundkörper 1.12 und den genannten Resten Q: Table 12 - with base 1:12 and said radicals Q:

Figure imgf000094_0001

Figure imgf000094_0002

Figure imgf000094_0003

Figure imgf000094_0004

Tabelle 13 - mit Grundkörper 1.13 und den genannten Resten Q: Table 13 - with base 1:13 and said radicals Q:

Figure imgf000095_0001

Figure imgf000095_0002

Figure imgf000095_0003

Figure imgf000095_0004

Tabelle 14 - mit Grundkörper 1.14 und den genannten Resten Q: Table 14 - with base 1:14 and said radicals Q:

Figure imgf000096_0001

Figure imgf000096_0002

Figure imgf000096_0003

Figure imgf000096_0004

Tabelle 15 - mit Grundkörper 1.15 und den genannten Resten Q: Table 15 - with base 1.15 and said radicals Q:

Figure imgf000097_0001

Figure imgf000097_0002

Figure imgf000097_0003

Figure imgf000097_0004

Tabelle 16 - mit Grundkörper 1.16 und den genannten Resten Q: Table 16 - with base 1:16 and said radicals Q:

Figure imgf000098_0001

Figure imgf000098_0002

Figure imgf000098_0003

Figure imgf000098_0004

Tabelle 17 - mit Grundkörper 1.17 und den genannten Resten Q: Table 17 - with body and said radicals 1:17 Q:

Figure imgf000099_0001

Figure imgf000099_0002

Figure imgf000099_0003

Figure imgf000099_0004

Tabelle 18 - mit Grundkörper 1.18 und den genannten Resten Q: Table 18 - with base 1:18 and said radicals Q:

Figure imgf000100_0001

Figure imgf000100_0002

Figure imgf000100_0003

Figure imgf000100_0004

Tabelle 19 - mit Grundkörper 1.19 und den genannten Resten Q: Table 19 - with base 1:19 and said radicals Q:

Figure imgf000101_0001

Figure imgf000101_0002

Figure imgf000101_0003

Figure imgf000101_0004

Tabelle 20 - mit Grundkörper 1.20 und den genannten Resten Q: Table 20 - with base 1.20 said radicals Q:

Figure imgf000102_0001

Figure imgf000102_0002

Figure imgf000102_0003

Figure imgf000102_0004

Tabelle 21 - mit Grundkörper 1.21 und den genannten Resten Q: Table 21 - with base 1.21 said radicals Q:

Figure imgf000103_0001

Figure imgf000103_0002

Figure imgf000103_0003

Figure imgf000103_0004

Tabelle 22 - mit Grundkörper 1.22 und den genannten Resten Q: Table 22 - with base 1:22 and said radicals Q:

Figure imgf000104_0001

Figure imgf000104_0002

Figure imgf000104_0003

Figure imgf000104_0004

Tabelle 23 - mit Grundkörper 1.23 und den genannten Resten Q: Table 23 - with base 1:23 and said radicals Q:

Figure imgf000105_0001

Figure imgf000105_0002

Figure imgf000105_0003

Figure imgf000105_0004

Tabelle 24 - mit Grundkörper 1.24 und den genannten Resten Q: Table 24 - with base 1:24 and said radicals Q:

Figure imgf000106_0001

Figure imgf000106_0002

Figure imgf000106_0003

Figure imgf000106_0004

Tabelle 25 - mit Grundkörper 1.25 und den genannten Resten Q: Table 25 - with base 1:25 and said radicals Q:

Figure imgf000107_0001

Figure imgf000107_0002

Figure imgf000107_0003

Figure imgf000107_0004

Tabelle 26 - mit Grundkörper 1.26 und den genannten Resten Q: Table 26 - with base 1:26 and said radicals Q:

Figure imgf000108_0001

Figure imgf000108_0002

Figure imgf000108_0003

Figure imgf000108_0004

Tabelle 27 - mit Grundkörper 1.27 und den genannten Resten Q: Table 27 - with base 1:27 and said radicals Q:

Figure imgf000109_0001

Figure imgf000109_0002

Figure imgf000109_0003

Figure imgf000109_0004

Tabelle 28 - mit Grundkörper 1.28 und den genannten Resten Q: Table 28 - with base 1:28 and said radicals Q:

Figure imgf000110_0001

Figure imgf000110_0002

Figure imgf000110_0003

Figure imgf000110_0004

Tabelle 29 - mit Grundkörper 1.29 und den genannten Resten Q: Table 29 - with base 1:29 and said radicals Q:

Figure imgf000111_0001

Figure imgf000111_0002

Figure imgf000111_0003

Figure imgf000111_0004

Tabelle 30 - mit Grundkörper 1.30 und den genannten Resten Q: Table 30 - with base 1:30 and said radicals Q:

Figure imgf000112_0001

Figure imgf000112_0002

Figure imgf000112_0003

Figure imgf000112_0004

Tabelle 31 - mit Grundkörper 1.31 und den genannten Resten Q: Table 31 - with base 1.31 and said radicals Q:

Figure imgf000113_0001

Figure imgf000113_0002

Figure imgf000113_0003

Figure imgf000113_0004

Tabelle 32 - mit Grundkörper 1.32 und den genannten Resten Q: Table 32 - with base 1:32 and said radicals Q:

Figure imgf000114_0001

Figure imgf000114_0002

Figure imgf000114_0003

Figure imgf000114_0004

Tabelle 33 - mit Grundkörper 1.33 und den genannten Resten Q: Table 33 - with base 1:33 and said radicals Q:

Figure imgf000115_0001

Figure imgf000115_0002

Figure imgf000115_0003

Figure imgf000115_0004

Tabelle 34 - mit Grundkörper 1.34 und den genannten Resten Q: Table 34 - with base 1:34 and said radicals Q:

Figure imgf000116_0001

Figure imgf000116_0002

Figure imgf000116_0003

Figure imgf000116_0004

Tabelle 35 - mit Grundkörper 1.35 und den genannten Resten Q: Table 35 - with base 1:35 and said radicals Q:

Figure imgf000117_0001

Figure imgf000117_0002

Figure imgf000117_0003

Figure imgf000117_0004

Tabelle 36 - mit Grundkörper 1.36 und den genannten Resten Q: Table 36 - with base 1:36 and said radicals Q:

Figure imgf000118_0001

Figure imgf000118_0002

Figure imgf000118_0003

Figure imgf000118_0004

Tabelle 37 - mit Grundkörper 1.37 und den genannten Resten Q: Table 37 - with base 1:37 and said radicals Q:

Figure imgf000119_0001

Figure imgf000119_0002

Figure imgf000119_0003

Figure imgf000119_0004

Tabelle 38 - mit Grundkörper 1.38 und den genannten Resten Q: Table 38 - with base 1:38 and said radicals Q:

Figure imgf000120_0001

Figure imgf000120_0002

Figure imgf000120_0003

Figure imgf000120_0004

Tabelle 39 - mit Grundkörper 1.39 und den genannten Resten Q: Table 39 - with base 1:39 and said radicals Q:

Figure imgf000121_0001

Figure imgf000121_0002

Figure imgf000121_0003

Figure imgf000121_0004

Tabelle 40 - mit Grundkörper 1.40 und den genannten Resten Q: Table 40 - with base 1:40 and said radicals Q:

Figure imgf000122_0001

Figure imgf000122_0002

Figure imgf000122_0003

Figure imgf000122_0004

Tabelle 41 - mit Grundkörper 1.41 und den genannten Resten Q: Table 41 - with base 1:41 and said radicals Q:

Figure imgf000123_0001

Figure imgf000123_0002

Figure imgf000123_0003

Figure imgf000123_0004

Tabelle 42 - mit Grundkörper 1.42 und den genannten Resten Q: Table 42 - with base 1:42 and said radicals Q:

Figure imgf000124_0001

Figure imgf000124_0002

Figure imgf000124_0003

Figure imgf000124_0004

Tabelle 43 - mit Grundkörper 1.43 und den genannten Resten Q: Table 43 - with base 1:43 and said radicals Q:

Figure imgf000125_0001

Figure imgf000125_0002

Figure imgf000125_0003

Figure imgf000125_0004

Tabelle 44 - mit Grundkörper 1.44 und den genannten Resten Q: Table 44 - with base 1.44 and said radicals Q:

Figure imgf000126_0001

Figure imgf000126_0002

Figure imgf000126_0003

Figure imgf000126_0004

Tabelle 45 - mit Grundkörper 1.45 und den genannten Resten Q: Table 45 - with base 1:45 and said radicals Q:

Figure imgf000127_0001

Figure imgf000127_0002

Figure imgf000127_0003

Figure imgf000127_0004

Tabelle 46 - mit Grundkörper 1.46 und den genannten Resten Q: Table 46 - with base 1:46 and said radicals Q:

Figure imgf000128_0001

Figure imgf000128_0002

Figure imgf000128_0003

Figure imgf000128_0004

Tabelle 47 - mit Grundkörper 1.47 und den genannten Resten Q: Table 47 - with base 1:47 and said radicals Q:

Figure imgf000129_0001

Figure imgf000129_0002

Figure imgf000129_0003

Figure imgf000129_0004

Tabelle 48 - mit Grundkörper 1.48 und den genannten Resten Q: Table 48 - with base 1:48 and said radicals Q:

Figure imgf000130_0001

Figure imgf000130_0002

Figure imgf000130_0003

Figure imgf000130_0004

Tabelle 49 - mit Grundkörper 1.49 und den genannten Resten Q: Table 49 - with base 1:49 and said radicals Q:

Figure imgf000131_0001

Figure imgf000131_0002

Figure imgf000131_0003

Figure imgf000131_0004

Tabelle 50 - mit Grundkörper 1.50 und den genannten Resten Q: Table 50 - with base 1:50 and said radicals Q:

Figure imgf000132_0001

Figure imgf000132_0002

Figure imgf000132_0003

Figure imgf000132_0004

Tabelle 51 - mit Grundkörper 1.51 und den genannten Resten Q: Table 51 - with base 1:51 and said radicals Q:

Figure imgf000133_0001

Figure imgf000133_0002

Figure imgf000133_0003

Figure imgf000133_0004

Tabelle 52 - mit Grundkörper 1.52 und den genannten Resten Q: Table 52 - with base 1:52 and said radicals Q:

Figure imgf000134_0001

Figure imgf000134_0002

Figure imgf000134_0003

Figure imgf000134_0004

Tabelle 53 - mit Grundkörper 1.53 und den genannten Resten Q: Table 53 - with base 1:53 and said radicals Q:

Figure imgf000135_0001

Figure imgf000135_0002

Figure imgf000135_0003

Figure imgf000135_0004

Tabelle 54 - mit Grundkörper 1.54 und den genannten Resten Q: Table 54 - with base 1:54 and said radicals Q:

Figure imgf000136_0001

Figure imgf000136_0002

Figure imgf000136_0003

Figure imgf000136_0004

Tabelle 55 - mit Grundkörper 1.55 und den genannten Resten Q: Table 55 - with base 1:55 and said radicals Q:

Figure imgf000137_0001

Figure imgf000137_0002

Figure imgf000137_0003

Figure imgf000137_0004

Tabelle 56 - mit Grundkörper 1.56 und den genannten Resten Q: Table 56 - with base 1:56 and said radicals Q:

Figure imgf000138_0001

Figure imgf000138_0002

Figure imgf000138_0003

Figure imgf000138_0004

Tabelle 57 - mit Grundkörper 1.57 und den genannten Resten Q: Table 57 - with base 1:57 and said radicals Q:

Figure imgf000139_0001

Figure imgf000139_0002

Figure imgf000139_0003

Figure imgf000139_0004

Tabelle 58 - mit Grundkörper 1.58 und den genannten Resten Q: Table 58 - with base 1:58 and said radicals Q:

Figure imgf000140_0001

Figure imgf000140_0002

Figure imgf000140_0003

Figure imgf000140_0004

Tabelle 59 - mit Grundkörper 1.59 und den genannten Resten Q: Table 59 - with base 1:59 and said radicals Q:

Figure imgf000141_0001

Figure imgf000141_0002

Figure imgf000141_0003

Figure imgf000141_0004

Tabelle 60 - mit Grundkörper 1.60 und den genannten Resten Q: Table 60 - with base 1.60 and said radicals Q:

Figure imgf000142_0001

Figure imgf000142_0002

Figure imgf000142_0003

Figure imgf000142_0004

Tabelle 61 - mit Grundkörper 1.61 und den genannten Resten Q: Table 61 - with base 1.61 and said radicals Q:

Figure imgf000143_0001

Figure imgf000143_0002

Figure imgf000143_0003

Figure imgf000143_0004

Tabelle 62 - mit Grundkörper 1.62 und den genannten Resten Q: Table 62 - with base 1.62 and said radicals Q:

Figure imgf000144_0001

Figure imgf000144_0002

Figure imgf000144_0003

Figure imgf000144_0004

Tabelle 63 - mit Grundkörper 1.63 und den genannten Resten Q: Table 63 - with base 1.63 and said radicals Q:

Figure imgf000145_0001

Figure imgf000145_0002

Figure imgf000145_0003

Figure imgf000145_0004

Tabelle 64 - mit Grundkörper 1.64 und den genannten Resten Q: Table 64 - with base 1.64 and said radicals Q:

Figure imgf000146_0001

Figure imgf000146_0002

Figure imgf000146_0003

Figure imgf000146_0004

Tabelle 65 - mit Grundkörper 1.65 und den genannten Resten Q: Table 65 - with base 1.65 and said radicals Q:

Figure imgf000147_0001

Figure imgf000147_0002

Figure imgf000147_0003

Figure imgf000147_0004

Tabelle 66 - mit Grundkörper 1.66 und den genannten Resten Q: Table 66 - with base 1.66 and said radicals Q:

Figure imgf000148_0001

Figure imgf000148_0002

Figure imgf000148_0003

Figure imgf000148_0004

Tabelle 67 - mit Grundkörper 1.67 und den genannten Resten Q: Table 67 - with base 1.67 and said radicals Q:

Figure imgf000149_0001

Figure imgf000149_0002

Figure imgf000149_0003

Figure imgf000149_0004

Tabelle 68 - mit Grundkörper 1.68 und den genannten Resten Q: Table 68 - with base 1.68 and said radicals Q:

Figure imgf000150_0001

Figure imgf000150_0002

Figure imgf000150_0003

Figure imgf000150_0004

Tabelle 69 - mit Grundkörper 1.69 und den genannten Resten Q: Table 69 - with base 1.69 and said radicals Q:

Figure imgf000151_0001

Figure imgf000151_0002

Figure imgf000151_0003

Figure imgf000151_0004

Tabelle 70 - mit Grundkörper 1.70 und den genannten Resten Q: Table 70 - with base 1.70 and said radicals Q:

Figure imgf000152_0001

Figure imgf000152_0002

Figure imgf000152_0003

Figure imgf000152_0004

Tabelle 71 - mit Grundkörper 1.71 und den genannten Resten Q: Table 71 - with base 1.71 and said radicals Q:

Figure imgf000153_0001

Figure imgf000153_0002

Figure imgf000153_0003

Figure imgf000153_0004

Tabelle 72 - mit Grundkörper 1.72 und den genannten Resten Q: Table 72 - with base 1.72 and said radicals Q:

Figure imgf000154_0001

Figure imgf000154_0002

Figure imgf000154_0003

Figure imgf000154_0004

Tabelle 73 - mit Grundkörper 1.73 und den genannten Resten Q: Table 73 - with base 1.73 and said radicals Q:

Figure imgf000155_0001

Figure imgf000155_0002

Figure imgf000155_0003

Figure imgf000155_0004

Tabelle 74 - mit Grundkörper 1.74 und den genannten Resten Q: Table 74 - with base 1.74 and said radicals Q:

Figure imgf000156_0001

Figure imgf000156_0002

Figure imgf000156_0003

Figure imgf000156_0004

Tabelle 75 - mit Grundkörper 1.75 und den genannten Resten Q: Table 75 - with base 1.75 and said radicals Q:

Figure imgf000157_0001

Figure imgf000157_0002

Figure imgf000157_0003

Figure imgf000157_0004

Tabelle 76 - mit Grundkörper 1.76 und den genannten Resten Q: Table 76 - with base 1.76 and said radicals Q:

Figure imgf000158_0001

Figure imgf000158_0002

Figure imgf000158_0003

Figure imgf000158_0004

Tabelle 77 - mit Grundkörper 1.77 und den genannten Resten Q: Table 77 - with base 1.77 and said radicals Q:

Figure imgf000159_0001

Figure imgf000159_0002

Figure imgf000159_0003

Figure imgf000159_0004

Tabelle 78 - mit Grundkörper 1.78 und den genannten Resten Q: Table 78 - with base 1.78 and said radicals Q:

Figure imgf000160_0001

Figure imgf000160_0002

Figure imgf000160_0003

Figure imgf000160_0004

Tabelle 79 - mit Grundkörper 1.79 und den genannten Resten Q: Table 79 - with base 1.79 and said radicals Q:

Figure imgf000161_0001

Figure imgf000161_0002

Figure imgf000161_0003

Figure imgf000161_0004

Tabelle 80 - mit Grundkörper 1.80 und den genannten Resten Q: Table 80 - with base 1.80 and said radicals Q:

Figure imgf000162_0001

Figure imgf000162_0002

Figure imgf000162_0003

Figure imgf000162_0004

Tabelle 81 - mit Grundkörper 1.81 und den genannten Resten Q: Table 81 - with base 1.81 and said radicals Q:

Figure imgf000163_0001

Figure imgf000163_0002

Figure imgf000163_0003

Figure imgf000163_0004

Tabelle 82 - mit Grundkörper 1.82 und den genannten Resten Q: Table 82 - with base 1.82 and said radicals Q:

Figure imgf000164_0001

Figure imgf000164_0002

Figure imgf000164_0003

Figure imgf000164_0004

Tabelle 83 - mit Grundkörper 1.83 und den genannten Resten Q: Table 83 - with base 1.83 and said radicals Q:

Figure imgf000165_0001

Figure imgf000165_0002

Figure imgf000165_0003

Figure imgf000165_0004

Tabelle 84 - mit Grundkörper 1.84 und den genannten Resten Q: Table 84 - with base 1.84 and said radicals Q:

Figure imgf000166_0001

Figure imgf000166_0002

Figure imgf000166_0003

Figure imgf000166_0004

Tabelle 85 - mit Grundkörper 1.85 und den genannten Resten Q: Table 85 - with base 1.85 and said radicals Q:

Figure imgf000167_0001

Figure imgf000167_0002

Figure imgf000167_0003

Figure imgf000167_0004

Tabelle 86 - mit Grundkörper 1.86 und den genannten Resten Q: Table 86 - with base 1.86 and said radicals Q:

Figure imgf000168_0001

Figure imgf000168_0002

Figure imgf000168_0003

Figure imgf000168_0004

Tabelle 87 - mit Grundkörper 1.87 und den genannten Resten Q: Table 87 - with base 1.87 and said radicals Q:

Figure imgf000169_0001

Figure imgf000169_0002

Figure imgf000169_0003

Figure imgf000169_0004

Tabelle 88 - mit Grundkörper 1.88 und den genannten Resten Q: Table 88 - with base 1.88 and said radicals Q:

Figure imgf000170_0001

Figure imgf000170_0002

Figure imgf000170_0003

Figure imgf000170_0004

Tabelle 89 - mit Grundkörper 1.89 und den genannten Resten Q: Table 89 - with base 1.89 and said radicals Q:

Figure imgf000171_0001

Figure imgf000171_0002

Figure imgf000171_0003

Figure imgf000171_0004

Tabelle 90 - mit Grundkörper 1.90 und den genannten Resten Q: Table 90 - with base 1.90 and said radicals Q:

Figure imgf000172_0001

Figure imgf000172_0002

Figure imgf000172_0003

Figure imgf000172_0004

Tabelle 91 - mit Grundkörper 1.91 und den genannten Resten Q: Table 91 - with base 1.91 and said radicals Q:

Figure imgf000173_0001

Figure imgf000173_0002

Figure imgf000173_0003

Figure imgf000173_0004

Tabelle 92 - mit Grundkörper 1.92 und den genannten Resten Q: Table 92 - with base 1.92 and said radicals Q:

Figure imgf000174_0001

Figure imgf000174_0002

Figure imgf000174_0003

Figure imgf000174_0004

Tabelle 93 - mit Grundkörper 1.93 und den genannten Resten Q: Table 93 - with base 1.93 and said radicals Q:

Figure imgf000175_0001

Figure imgf000175_0002

Figure imgf000175_0003

Figure imgf000175_0004

Tabelle 94 - mit Grundkörper 1.94 und den genannten Resten Q: Table 94 - with base 1.94 and said radicals Q:

Figure imgf000176_0001

Figure imgf000176_0002

Figure imgf000176_0003

Figure imgf000176_0004

Tabelle 95 - mit Grundkörper 1.95 und den genannten Resten Q: Table 95 - with base 1.95 and said radicals Q:

Figure imgf000177_0001

Figure imgf000177_0002

Figure imgf000177_0003

Figure imgf000177_0004

Tabelle 96 - mit Grundkörper 1.96 und den genannten Resten Q: Table 96 - with base 1.96 and said radicals Q:

Figure imgf000178_0001

Figure imgf000178_0002

Figure imgf000178_0003

Figure imgf000178_0004

Tabelle 97 - mit Grundkörper 1.97 und den genannten Resten Q: Table 97 - with base 1.97 and said radicals Q:

Figure imgf000179_0001

Figure imgf000179_0002

Figure imgf000179_0003

Figure imgf000179_0004

Tabelle 98 - mit Grundkörper 1.98 und den genannten Resten Q: Table 98 - with base 1.98 and said radicals Q:

Figure imgf000180_0001

Figure imgf000180_0002

Figure imgf000180_0003

Figure imgf000180_0004

Tabelle 99 - mit Grundkörper 1.99 und den genannten Resten Q: Table 99 - with base 1.99 and said radicals Q:

Figure imgf000181_0001

Figure imgf000181_0002

Figure imgf000181_0003

Figure imgf000181_0004

Tabelle 100 - mit Grundkörper 1.100 und den genannten Resten Q: Table 100 - with base 1100 and said radicals Q:

Figure imgf000182_0001

Figure imgf000182_0002
Figure imgf000182_0003
Figure imgf000182_0004

Tabelle 101 - mit Grundkörper 1.101 und den genannten Resten Q: Table 101 - with base 1101 and said radicals Q:

Figure imgf000183_0001

Figure imgf000183_0002
Figure imgf000183_0003
Figure imgf000183_0004

Tabelle 102 - mit Grundkörper 1.102 und den genannten Resten Q: Table 102 - with base 1102 and said radicals Q:

Figure imgf000184_0001

Figure imgf000184_0002
Figure imgf000184_0003
Figure imgf000184_0004

Tabelle 103 - mit Grundkörper 1.103 und den genannten Resten Q: Table 103 - with base 1103 and said radicals Q:

Figure imgf000185_0001

Figure imgf000185_0002
Figure imgf000185_0003
Figure imgf000185_0004

Tabelle 104 - mit Grundkörper 1.104 und den genannten Resten Q: Table 104 - with base 1104 and said radicals Q:

Figure imgf000186_0001

Figure imgf000186_0002
Figure imgf000186_0003
Figure imgf000186_0004

Tabelle 105 - mit Grundkörper 1.105 und den genannten Resten Q: Table 105 - with base 1105 and said radicals Q:

Figure imgf000187_0001

Figure imgf000187_0002
Figure imgf000187_0003
Figure imgf000187_0004

Tabelle 106 - mit Grundkörper 1.106 und den genannten Resten Q: Table 106 - with base 1106 and said radicals Q:

Figure imgf000188_0001

Figure imgf000188_0002
Figure imgf000188_0003
Figure imgf000188_0004

Tabelle 107 - mit Grundkörper 1.107 und den genannten Resten Q: Table 107 - with base 1107 and said radicals Q:

Figure imgf000189_0001

Figure imgf000189_0002
Figure imgf000189_0003
Figure imgf000189_0004

Tabelle 108 - mit Grundkörper 1.108 und den genannten Resten Q: Table 108 - with base 1108 and said radicals Q:

Figure imgf000190_0001

Figure imgf000190_0002
Figure imgf000190_0003
Figure imgf000190_0004

Tabelle 109 - mit Grundkörper 1.109 und den genannten Resten Q: Table 109 - with base 1109 and said radicals Q:

Figure imgf000191_0001

Figure imgf000191_0002
Figure imgf000191_0003
Figure imgf000191_0004

Tabelle 110 - mit Grundkörper 1.110 und den genannten Resten Q: Table 110 - with base 1110 and said radicals Q:

Figure imgf000192_0001

Figure imgf000192_0002
Figure imgf000192_0003
Figure imgf000192_0004

Tabelle 111 - mit Grundkörper 1.111 und den genannten Resten Q: Table 111 - with base 1111 and said radicals Q:

Figure imgf000193_0001

Figure imgf000193_0002
Figure imgf000193_0003
Figure imgf000193_0004

Tabelle 112 - mit Grundkörper 1.112 und den genannten Resten Q: Table 112 - with base 1112 and said radicals Q:

Figure imgf000194_0001

Figure imgf000194_0002
Figure imgf000194_0003
Figure imgf000194_0004

Spektroskopische Daten ausgewählter chemischer Beispiele: Beispiel No.1.1-1: Spectroscopic data of selected chemical examples: Example No.1.1-1:

1H-NMR (400 MHz, CDCI 3 δ, ppm) 7.77 (d, 2H), 7.71 (d, 2H), 5.02 (br. t, 1 H, NH), 4.06 (d, 2H). 1H-NMR (400 MHz, CDCl 3 δ, ppm) 7.77 (d, 2H), 7.71 (d, 2H), 5:02 (br. T, 1 H, NH), 4:06 (d, 2H).

Beispiel No.1.1-2: Example No.1.1-2:

1 H-NMR (400 MHz, CDCI3 δ, ppm) 7.78 (d, 2H), 7.73 (d, 2H), 5.11 (br. d, 1 H, NH), 4.36 (quint, 1H), 1.59 (d, 3H). 1 H-NMR (400 MHz, CDCl 3 δ, ppm) 7.78 (d, 2H), 7.73 (d, 2H), 5.11 (br. D, 1 H, NH), 4:36 (quint, 1H), 1:59 (d, 3H).

Beispiel No.1.1-3: Example No.1.1-3:

1 H-NMR(400MHz, CDCI3 δ, ppm) 7.81 (d, 2H), 7.69 (d, 2H), 5,17 (br. s, 1H, NH), 1.67 (s, 6H). 1 H-NMR (400MHz, CDCl 3 δ, ppm) 7.81 (d, 2H), 7.69 (d, 2H), 5.17 (br. S, 1H, NH), 1.67 (s, 6H).

Beispiel No.1.1-4: Example No.1.1-4:

1 H-NMR (400 MHz, CDCI3 δ, ppm) 7.78 (d, 2H), 7.72 (d, 2H), 5.27 (br. d, 1 H, NH), 4.06 (dd, 1H), 2.07 (m, 1H), 1.08 (d, 6H). 1 H-NMR (400 MHz, CDCl 3 δ, ppm) 7.78 (d, 2H), 7.72 (d, 2H), 5.27 (br. D, 1 H, NH), 4:06 (dd, 1H), 2:07 (m, 1H), 1:08 (d, 6H). Beispiel No.1.1-5: Example No.1.1-5:

1 H-NMR (400 MHz, CDCI3 δ, ppm) 7.80 (d, 2H), 7.68 (d, 2H), 4.98 (br. s, 1 H, NH), 1.82 (sext, 2H), 1.65 (s, 3H), 1.47 (sext, 2H), 0.96 (t, 3H). 1 H-NMR (400 MHz, CDCl 3 δ, ppm) 7.80 (d, 2H), 7.68 (d, 2H), 4.98 (br. S, 1 H, NH), 1.82 (sext, 2H), 1.65 (s, 3H), 1:47 (sext, 2H), 0.96 (t, 3H).

Beispiel No.1.1-9: Example No.1.1-9:

1H-NMR (400 MHz, CDCI3 δ, ppm) 7.81 (d, 2H), 7.71 (d, 2H), 5.44 (br. s, 1H, NH), 3.56 (d, 1H), 3.47 (d, 1H), 3.44 (s, 3H), 1.65 (s, 3H). 1H-NMR (400 MHz, CDCl 3 δ, ppm) 7.81 (d, 2H), 7.71 (d, 2H), 5:44 (br. S, 1H, NH), 3:56 (d, 1H), 3:47 (d, 1H) , 3:44 (s, 3H), 1.65 (s, 3H).

Beispiel No.1.1-11: Example No.1.1-11:

1 H-NMR (400 MHz, CDCI3 δ, ppm) 7.81 (d, 2H), 7.69 (d, 2H), 5.22 (br. s, 1 H, NH), 1.72 (s, 3H), 1.18 (m, 1H), 0.62 (m, 4H). 1 H-NMR (400 MHz, CDCl 3 δ, ppm) 7.81 (d, 2H), 7.69 (d, 2H), 5.22 (br. S, 1 H, NH), 1.72 (s, 3H), 1.18 (m, 1H), 0.62 (m, 4H). Beispiel No.1.1-12: Example No.1.1-12:

1 H-NMR (400 MHz, CDCI 3 δ, ppm) 7.80 (d, 2H), 7.69 (d, 2H), 4.72 (br. s, 1 H, NH), 1.92 (m, 4H), 1.00 (t, 6H). 1 H-NMR (400 MHz, CDCl 3 δ, ppm) 7.80 (d, 2H), 7.69 (d, 2H), 4.72 (br. S, 1 H, NH), 1.92 (m, 4H), 1.00 (t , 6H). Beispiel No.1.1-13: Example No.1.1-13:

1 H-NMR (400 MHz, CDCI3 δ, ppm) 7.80 (d, 2H), 7.71 (d, 2H), 4.92 (br. s, 1H, NH), 1.90 (m, 2H), 1.64 (s, 3H), 1.06 (t, 3H). 1 H-NMR (400 MHz, CDCl 3 δ, ppm) 7.80 (d, 2H), 7.71 (d, 2H), 4.92 (br. S, 1H, NH), 1.90 (m, 2H), 1.64 (s, 3H ), 1:06 (t, 3H).

Beispiel No.1.1-14: Example No.1.1-14:

1H-NMR(400MHz, CDCI3 δ, ppm) 7.82 (d, 2H), 7.69 (d, 2H), 5.02 (br. s, 1H, NH), 1.82 (m, 1 H), 1.78 (dd, 1 H), 1.69 (dd, 1 H), 1.68 (s, 3H), 0.99 (d, 6H). 1H-NMR (400MHz, CDCl 3 δ, ppm) 7.82 (d, 2H), 7.69 (d, 2H), 5:02 (br. S, 1H, NH), 1.82 (m, 1 H), 1.78 (dd, 1 H ), 1.69 (dd, 1 H), 1.68 (s, 3H), 0.99 (d, 6H).

Beispiel No.1.1-21: Example No.1.1-21:

1 H-NMR (400 MHz, CDCI3 δ, ppm) 7.82 (d, 2H), 7.71 (d, 2H), 5.03 (br. s, 1 H, NH), 1.75 (m, 2H), 1.62 (s, 3H), 1.08 (m, 1H), 1.02 (m, 3H), 0.92 (m, 3H). 1 H-NMR (400 MHz, CDCl 3 δ, ppm) 7.82 (d, 2H), 7.71 (d, 2H), 5:03 (br. S, 1 H, NH), 1.75 (m, 2H), 1.62 (s, 3H), 1.08 (m, 1H), 1.02 (m, 3H), 0.92 (m, 3H).

Beispiel No.1.1-23: Example No.1.1-23:

1 H-NMR (400 MHz, CDCI3 δ, ppm) 7.64 (d, 2H), 7.61 (d, 2H), 7.39 (m, 3H), 7.32 (m, 2H), 4.83 (br. s, 1H, NH), 3.21 (d, 1H), 3.06 (d, 1H), 1.68 (s, 3H). 1 H-NMR (400 MHz, CDCl 3 δ, ppm) 7.64 (d, 2H), 7.61 (d, 2H), 7:39 (m, 3H), 7:32 (m, 2H), 4.83 (br. S, 1H, NH ), 3.21 (d, 1H), 3:06 (d, 1H), 1.68 (s, 3H).

Beispiel No.1.1-24: Example No.1.1-24:

1 H-NMR (400 MHz, CDCI3 δ, ppm) 7.74 (d, 2H), 7.68 (d, 2H), 5.29 (br. t, 1 H, NH), 3.25 (q, 2H), 2.62 (t, 2H). 1 H-NMR (400 MHz, CDCl 3 δ, ppm) 7.74 (d, 2H), 7.68 (d, 2H), 5.29 (br. T, 1 H, NH), 3.25 (q, 2H), 2.62 (t, 2H). Beispiel No.1.1-28: Example No.1.1-28:

1 H-NMR (400 MHz, CDCI3 δ, ppm) 7.74 (d, 2H), 7.62 (d, 2H), 5.26 (br. d, 1 H, NH), 4.03 (q, 2H), 3.33 (m, 1H), 2.42 (dd, 1H), 2.31 (dd, 1H), 1.80 (m, 1H), 1.22 (t, 3H), 0.85 (d, 3H), 0.82 (d, 3H). 1 H-NMR (400 MHz, CDCl 3 δ, ppm) 7.74 (d, 2H), 7.62 (d, 2H), 5.26 (br. D, 1 H, NH), 4:03 (q, 2H), 3:33 (m, 1H), 2:42 (dd, 1H), 2.31 (dd, 1H), 1.80 (m, 1H), 1.22 (t, 3H), 0.85 (d, 3H), 0.82 (d, 3H). Beispiel No.1.1-33: Example No.1.1-33:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.71 (br. s, 1H, NH), 7.57 (d, 2H), 7.43 (d, 2H), 7.32 (d, 1H), 7.25 (d, 1H), 7.12 (m, 2H), 5.18 (t, 1H), 3.97 (q, 2H), 2.62 (m, 2H), 1.11 (t, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.71 (br. S, 1H, NH), 7:57 (d, 2H), 7:43 (d, 2H), 7:32 (d, 1H), 25.07 ( d, 1H), 7.12 (m, 2H), 5.18 (t, 1H), 3.97 (q, 2H), 2.62 (m, 2H), 1.11 (t, 3H).

Beispiel No.1.1-35: Example No.1.1-35:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.56 (br. s, 1H, NH), 7.58 (d, 2H), 7.42 (d, 2H), 7.31 (d, 2H), 7.07 (d, 2H), 4.61 (t, 1H), 3.48 (s, 3H), 2.70 (m, 2H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8:56 (br. S, 1H, NH), 7:58 (d, 2H), 7:42 (d, 2H), 7.31 (d, 2H), 7:07 ( d, 2H), 4.61 (t, 1H), 3:48 (s, 3H), 2.70 (m, 2H). Beispiel No.1.1-41: Example No.1.1-41:

1 H-NMR (400 MHz, CDCI 3 δ, ppm) 7.74 (d, 2H), 7.64 (d, 2H), 5.25-5.30 (br. d, 1 H, NH), 4.05-4.15 (m, 2H), 3.68-3.75 (m, 1H), 2.42 (m, 2H), 1.22-1.25 (t, 3H), 1.17-1.19 (d, 3H). 1 H-NMR (400 MHz, CDCl 3 δ, ppm) 7.74 (d, 2H), 7.64 (d, 2H), 5:25 to 5:30 (br. D, 1 H, NH), 4:05 to 4:15 (m, 2H) , 3.68-3.75 (m, 1H), 2:42 (m, 2H), 1:22 to 1:25 (t, 3H), 1:17 to 1:19 (d, 3H). Beispiel No.1.1-60: Example No.1.1-60:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.54 (br. d, 1H, NH), 7.55 (d, 2H), 7.43 (d, 2H), 7.12 (m, 5H), 4.66 (m, 1H), 3.94 (q, 2H), 2.71 (dd, 1H), 2.67 (dd, 1H), 1.08 (t, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8:54 (br. D, 1H, NH), 7:55 (d, 2H), 7:43 (d, 2H), 7.12 (m, 5H), 4.66 ( m, 1H), 3.94 (q, 2H), 2.71 (dd, 1H), 2.67 (dd, 1H), 1:08 (t, 3H). Beispiel No.1.1-61: Example No.1.1-61:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.05 (br. d, 1H, NH), 7.64 (d, 2H), 7.50 (d, 2H), 7.17 (m, 3H), 7.04 (m, 2H), 3.68 (m, 1H), 3.46 (s, 3H), 2.63 (m, 2H), 2.39 (m, 2H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8:05 (br. D, 1H, NH), 7.64 (d, 2H), 7.50 (d, 2H), 7.17 (m, 3H), 7:04 ( m, 2H), 3.68 (m, 1H), 3:46 (s, 3H), 2.63 (m, 2H), 2:39 (m, 2H). Beispiel No.1.1-62: Example No.1.1-62:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 7.89 (br. d, 1H, NH), 7.82 (d, 2H), 7.69 (d, 2H), 3.92 (q, 2H), 3.49 (m, 1H), 2.32 (dd, 1H), 2.28 (dd, 1H), 1.44 (m, 1H), 1.24 (m, 1H), 1.12 (t, 3H), 1.09 (m, 1H), 0.75 (d, 3H), 0.60 (d, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 7.89 (br. D, 1H, NH), 7.82 (d, 2H), 7.69 (d, 2H), 3.92 (q, 2H), 3:49 ( m, 1H), 2:32 (dd, 1H), 2.28 (dd, 1H), 1:44 (m, 1H), 1.24 (m, 1H), 1.12 (t, 3H), 1:09 (m, 1H), 0.75 (d , 3H), 0.60 (d, 3H). Beispiel No.1.1-63: Example No.1.1-63:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.64 (br. d, 1H, NH), 7.82 (d, 2H), 7.68 (d, 2H), 4.22 (m, 1H), 3.52 (s, 3H), 3.42 (s, 3H), 2.74 (dd, 1H), 2.61 (dd, 1H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.64 (br. D, 1H, NH), 7.82 (d, 2H), 7.68 (d, 2H), 4.22 (m, 1H), 3:52 ( s, 3H), 3:42 (s, 3H), 2.74 (dd, 1H), 2.61 (dd, 1H). Beispiel No.1.1-74: Example No.1.1-74:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.82 (s, 1H), 8.66 (br. d, 1H, NH), 7.78 (d, 2H), 7.57 (d, 2H), 7.31 (s, 1H), 4.21 (m, 1H), 3.77 (s, 3H), 3.46 (s, 3H), 3.04 (dd, 1H), 2.88 (dd, 1H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.82 (s, 1H), 8.66 (br. D, 1H, NH), 7.78 (d, 2H), 7:57 (d, 2H), 7.31 ( s, 1H), 4.21 (m, 1H), 3.77 (s, 3H), 3:46 (s, 3H), 3:04 (dd, 1H), 2.88 (dd, 1H).

Beispiel No.1.1-75: Example No.1.1-75:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.40 (br. d, 1H, NH), 7.79 (d, 2H), 7.66 (d, 2H), 3.57 (m, 1H), 3.38 (s, 3H), 1.90 (m, 1H), 0.80 (d, 3H), 0.78 (d, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8:40 (br. D, 1H, NH), 7.79 (d, 2H), 7.66 (d, 2H), 3:57 (m, 1H), 3:38 ( s, 3H), 1.90 (m, 1H), 0.80 (d, 3H), 0.78 (d, 3H).

Beispiel No.1.1-77: Example No.1.1-77:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.44 (br. d, 1H, NH), 7.79 (d, 2H), 7.67 (d, 2H), 3.77 (m, 1H), 3.39 (s, 3H), 1.57 (m, 1H), 2.42 (m, 2H), 0.81 (d, 3H), 0.71 (d, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8:44 (br. D, 1H, NH), 7.79 (d, 2H), 7.67 (d, 2H), 3.77 (m, 1H), 3:39 ( s, 3H), 1:57 (m, 1H), 2:42 (m, 2H), 0.81 (d, 3H), 0.71 (d, 3H).

Beispiel No.1.1-79: Example No.1.1-79:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.51 (br. m, 1H, NH), 7.82 (d, 2H), 7.68 (d, 2H), 3.98 (m, 1H), 3.44 (s, 3H), 2.41 (m, 1H), 2.32 (m, 1H), 1.94 (s, 3H), 1.82 (m, 1H), 1.77 (m, 1H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.51 (br. M, 1H, NH), 7.82 (d, 2H), 7.68 (d, 2H), 3.98 (m, 1H), 3.44 ( s, 3H), 2:41 (m, 1H), 2:32 (m, 1H), 1.94 (s, 3H), 1.82 (m, 1H), 1.77 (m, 1H).

Beispiel No.1.1-80: Example No.1.1-80:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.62 (br. d, 1H, NH), 7.68 (d, 2H), 7.50 (d, 2H), 7.19 (m, 3H), 7.11 (m, 2H), 3.97 (m, 1H), 3.81 (q, 2H), 2.92 (dd, 1H), 2.78 (dd, 1H), 0.97 (t, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.62 (br. D, 1H, NH), 7.68 (d, 2H), 7.50 (d, 2H), 7.19 (m, 3H), 7.11 ( m, 2H), 3.97 (m, 1H), 3.81 (q, 2H), 2.92 (dd, 1H), 2.78 (dd, 1H), 0.97 (t, 3H).

Beispiel No.1.1-82: Example No.1.1-82:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.65 (br. d, 1H, NH), 8.42 (d, 1H), 8.40 (d, 1H), 7.68 (m, 3H), 7.47 (d, 2H), 7.30 (dd, 1H), 4.11 (m, 1H), 3.42 (s, 3H), 3.02 (dd, 1H), 2.80 (dd, 1H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.65 (br. D, 1H, NH), 8:42 (d, 1H), 8.40 (d, 1H), 7.68 (m, 3H), 7:47 ( d, 2H), 7.30 (dd, 1H), 4.11 (m, 1H), 3:42 (s, 3H), 3:02 (dd, 1H), 2.80 (dd, 1H). Beispiel No.1.1-83: Example No.1.1-83:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 7.86 (br. d, 1H, NH), 7.80 (d, 2H), 7.68 (d, 2H), 3.41 (m, 1H), 3.37 (s, 3H), 2.45 (dd, 1H), 2.17 (dd, 1H), 1.62 (m, 2H), 1.55 (m, 2H), 1.49 (m, 1H), 1.28 (m, 1H), 1.05 (m, 3H), 0.88 (m, 1H), 0.82 (m, 1H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 7.86 (br. D, 1H, NH), 7.80 (d, 2H), 7.68 (d, 2H), 3:41 (m, 1H), 3:37 ( s, 3H), 2:45 (dd, 1H), 2.17 (dd, 1H), 1.62 (m, 2H), 1:55 (m, 2H), 1:49 (m, 1H), 1.28 (m, 1H), 1:05 (m , 3H), 0.88 (m, 1H), 0.82 (m, 1H).

Beispiel No.1.1-84: Example No.1.1-84:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.43 (br. d, 1H, NH), 7.79 (d, 2H), 7.67 (d, 2H), 6.76 (br. t, 1H, NH), 3.78 (m, 1H), 3.39 (s, 3H), 2.82 (m, 2H), 1.59 (m, 1H), 1.50 (m, 1H), 1.36 (s, 9H), 1.20 (m, 2H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8:43 (br. D, 1H, NH), 7.79 (d, 2H), 7.67 (d, 2H), 6.76 (br. T, 1H, NH ), 3.78 (m, 1H), 3:39 (s, 3H), 2.82 (m, 2H), 1:59 (m, 1H), 1:50 (m, 1H), 1:36 (s, 9H), 1.20 (m, 2H) ,

Beispiel No.1.1-86: Example No.1.1-86:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.68 (br. d, 1H, NH), 7.80 (d, 2H), 7.70 (d, 2H), 3.99 (m, 1H), 3.43 (s, 3H), 2.89 (s, 1H), 2.58 (m, 1H), 2.50 (m, 1H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.68 (br. D, 1H, NH), 7.80 (d, 2H), 7.70 (d, 2H), 3.99 (m, 1H), 3:43 ( s, 3H), 2.89 (s, 1H), 2:58 (m, 1H), 2:50 (m, 1H). Beispiel No.1.1-90: Example No.1.1-90:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.62 (br. d, 1H, NH), 7.66 (d, 2H), 7.47 (d, 2H), 7.14 (m, 2H), 6.98 (m, 2H), 3.97 (m, 1H), 3.44 (s, 3H), 2.96 (dd, 1H), 2.73 (dd, 1H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.62 (br. D, 1H, NH), 7.66 (d, 2H), 7:47 (d, 2H), 7.14 (m, 2H), 6.98 ( m, 2H), 3.97 (m, 1H), 3:44 (s, 3H), 2.96 (dd, 1H), 2.73 (dd, 1H). Beispiel No.1.1-92: Example No.1.1-92:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.50 (br. d, 1H, NH), 7.70 (d, 2H), 7.68 (d, 2H), 7.28 (m, 6H), 7.19 (m, 4H), 4.97 (d, 1H), 4.87 (d, 1H), 4.45 (d, 1H), 4.27 (d, 1H), 4.08 (m, 1H), 3.96 (m, 1H), 0.93 (d, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8:50 (br. D, 1H, NH), 7.70 (d, 2H), 7.68 (d, 2H), 7.28 (m, 6H), 7.19 ( m, 4H), 4.97 (d, 1H), 4.87 (d, 1H), 4.45 (d, 1H), 4.27 (d, 1H), 4:08 (m, 1H), 3.96 (m, 1H), 0.93 (d , 3H). Beispiel No.1.1-103: Example No.1.1-103:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.98 (br. d, 1H, NH), 7.80 (d, 2H), 7.68 (d, 2H), 4.32 (m, 1H), 3.87 (q, 2H), 2.78 (dd, 1H), 2.42 (dd, 1H), 1.11 (t, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.98 (br. D, 1H, NH), 7.80 (d, 2H), 7.68 (d, 2H), 4:32 (m, 1H), 3.87 ( q, 2H), 2.78 (dd, 1H), 2.42 (dd, 1H), 1.11 (t, 3H).

Beispiel No.1.1-106: Example No.1.1-106:

1H-NMR (400 MHz, d 6 -DMSO δ, ppm) 13.74 (br. s, 1H, NH), 8.93 (br. d, 1H, NH), 8.90 (s, 1H), 7.60 (d, 2H), 7.43 (s, 1H), 7.38 (d, 2H), 4.36 (m, 1H), 3.74 (s, 3H), 3.22 (dd, 1H), 3.18 (dd, 1H). 1H-NMR (400 MHz, d 6 -DMSO δ, ppm) 13.74 (br. S, 1H, NH), 8.93 (br. D, 1H, NH), 8.90 (s, 1H), 7.60 (d, 2H) , 7:43 (s, 1H), 7:38 (d, 2H), 4:36 (m, 1H), 3.74 (s, 3H), 3.22 (dd, 1H), 3.18 (dd, 1H). Beispiel No.1.1-108: Example No.1.1-108:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.75 (br. d, 1H, NH), 8.42 (m, 2H), 7.64 (d, 2H), 7.52 (d, 2H), 7.28 (m, 2H), 4.68 (q, 2H), 3.48 (s, 3H), 2.73 (m, 2H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.75 (br. D, 1H, NH), 8:42 (m, 2H), 7.64 (d, 2H), 7:52 (d, 2H), 7.28 ( m, 2H), 4.68 (q, 2H), 3:48 (s, 3H), 2.73 (m, 2H).

Beispiel No.1.2-1: Example No.1.2-1:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.88 (br. t, 1H, NH), 8.59 (d, 1H), 8.27 (d, 1H), 8.18 (d, 1H), 8.11 (d, 1H), 7.72 (m, 1H), 7.68 (m, 2H), 4.09 (d, 2H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.88 (br. T, 1H, NH), 8:59 (d, 1H), 8.27 (d, 1H), 8.18 (d, 1H), 8.11 (d, 1H), 7.72 (m, 1H), 7.68 (m, 2H), 4:09 (d, 2H). Beispiel No. Example No. I.2-2: I.2-2:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.99 (br. d, 1H, NH), 8.57 (d, 1H), 8.28 (d, 1H), 8.19 (d, 1H), 8.11 (d, 1H), 7.73 (m, 1H), 7.67 (m, 2H), 4.42 (m, 1H), 1.29 (d, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.99 (br. D, 1H, NH), 8.57 (d, 1H), 8.28 (d, 1H), 8.19 (d, 1H), 8.11 (d, 1H), 7.73 (m, 1H), 7.67 (m, 2H), 4.42 (m, 1H), 1.29 (d, 3H). Beispiel No. Example No. I.2-3: I.2-3:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.88 (br. s, 1H, NH), 8.61 (d, 1H), 8.26 (d, 1H), 8.23 (d, 1H), 8.10 (d, 1H), 7.72 (m, 1H), 7.68 (m, 2H), 1.49 (s, 6H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.88 (br. S, 1H, NH), 8.61 (d, 1H), 8.26 (d, 1H), 8.23 (d, 1H), 8.10 (d, 1H), 7.72 (m, 1H), 7.68 (m, 2H), 1:49 (s, 6H).

Beispiel No. Example No. I.2-4: I.2-4:

1H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.98 (br. d, 1H, NH), 8.53 (d, 1H), 8.28 (d, 1H), 8.20 (d, 1H), 8.10 (d, 1H), 7.73 (m, 1H), 7.67 (m, 2H), 4.12 (dd, 1H), 1.82 (m, 1H), 0.84 (d, 3H), 0.78 (d, 3H). 1H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.98 (br. D, 1H, NH), 8:53 (d, 1H), 8.28 (d, 1H), 8.20 (d, 1H), 10.08 ( d, 1H), 7.73 (m, 1H), 7.67 (m, 2H), 4.12 (dd, 1H), 1.82 (m, 1H), 0.84 (d, 3H), 0.78 (d, 3H).

Beispiel No. Example No. I.2-9: I.2-9:

1H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.91 (br. s, 1 H, NH), 8.60 (d, 1 H), 8.25 (d, 1H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.91 (br. S, 1 H, NH), 8.60 (d, 1 H), 8.25 (d,

1H), 8.23 (d, 1H), 8.10 (d, 1H), 7.70 (m, 1H), 7.65 (m, 2H), 3.59 (d, 1H), 3.40 (d, 1H), 3.19 (s, 3H), 1.48 (s, 3H). 1H), 8.23 (d, 1H), 8.10 (d, 1H), 7.70 (m, 1H), 7.65 (m, 2H), 3:59 (d, 1H), 3:40 (d, 1H), 3.19 (s, 3H ), 1:48 (s, 3H).

Beispiel No.1.2-13: Example No.1.2-13:

1H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.75 (br. s, 1 H, NH), 8.61 (d, 1 H), 8.23 (d, 1H), 8.21 (d, 1H), 8.09 (d, 1H), 7.71 (m, 1H), 7.66 (m, 2H), 1.84 (m, 1H), 1.75 (m, 1H), 1.44 (s, 3H), 0.74 (t, 3H). 1H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.75 (br. S, 1 H, NH), 8.61 (d, 1 H), 8.23 (d, 1H), 8.21 (d, 1H), 8:09 (d, 1H), 7.71 (m, 1H), 7.66 (m, 2H), 1.84 (m, 1H), 1.75 (m, 1H), 1:44 (s, 3H), 0.74 (t, 3H). Beispiel No.1.2-14: Example No.1.2-14:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.70 (br. s, 1H, NH), 8.60 (d, 1H), 8.24 (d, 1H), 8.22 (d, 1H), 8.10 (d, 1H), 7.73 (m, 1H), 7.69 (m, 2H), 1.78 (m, 1H), 1.66 (m, 1 H), 1.62 (m, 1 H), 1.48 (s, 3H), 0.80 (d, 3H), 0.72 (d, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.70 (br. S, 1H, NH), 8.60 (d, 1H), 8.24 (d, 1H), 8.22 (d, 1H), 8.10 (d, 1H), 7.73 (m, 1H), 7.69 (m, 2H), 1.78 (m, 1H), 1.66 (m, 1 H), 1.62 (m, 1 H), 1:48 (s, 3H); 0.80 (d, 3H), 0.72 (d, 3H).

Beispiel No. Example No. I.2-23: I.2-23:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.96 (br. s, 1H, NH), 8.62 (d, 1H), 8.22 (d, 1H), 8.13 (d, 1H), 8.08 (d, 1H), 7.72 (m, 1H), 7.68 (m, 1H), 7.59 (m, 1H), 7.24 (m, 2H), 7.21 (m, 3H), 3.20 (d, 1H), 3.06 (d, 1H), 1.39 (s, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.96 (br. S, 1H, NH), 8.62 (d, 1H), 8.22 (d, 1H), 8.13 (d, 1H), 8:08 (d, 1H), 7.72 (m, 1H), 7.68 (m, 1H), 7:59 (m, 1H), 7.24 (m, 2H), 7.21 (m, 3H), 3.20 (d, 1H), 3:06 ( d, 1H), 1:39 (s, 3H).

Beispiel No. Example No. I.2-24: I.2-24:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.62 (d, 1H), 8.39 (br. t, 1H, NH), 8.24 (d, 1H), 8.13 (d, 1H), 8.09 (d, 1H), 7.71 (m, 1H), 7.66 (m, 2H), 3.03 (m, 2H), 2.61 (m, 2H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.62 (d, 1H), 8.39 (br. T, 1H, NH), 8.24 (d, 1H), 8.13 (d, 1H), 8.09 (d, 1H), 7.71 (m, 1H), 7.66 (m, 2H), 3:03 (m, 2H), 2.61 (m, 2H).

Beispiel No. Example No. I.2-28: I.2-28:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.66 (br. d, 1H, NH), 8.21 (d, 1H), 8.13 (d, 1H), 8.06 (d, 1H), 8.04 (d, 1H), 7.69 (dd, 1H), 7.62 (m, 2H), 3.60 (q, 2H), 3.53 (m, 1 H), 2.34 (dd, 1 H), 2.12 (dd, 1 H), 1.62 (m, 1 H), 0.95 (t, 3H), 0.69 (d, 3H), 0.59 (d, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.66 (br. D, 1H, NH), 8.21 (d, 1H), 8.13 (d, 1H), 8:06 (d, 1H), 8:04 ( d, 1H), 7.69 (dd, 1H), 7.62 (m, 2H), 3.60 (q, 2H), 3:53 (m, 1 H), 2:34 (dd, 1 H), 2.12 (dd, 1 H), 1.62 (m, 1 H), 0.95 (t, 3H), 0.69 (d, 3H), 0:59 (d, 3H).

Beispiel No. Example No. I.2-34: I.2-34:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.62 (br. d, 1H, NH), 8.24 (d, 1H), 8.12 (d, 1H), 8.10 (d, 1H), 8.08 (d, 1H), 7.69 (dd, 1H), 7.66 (m, 2H), 3.87 (q, 2H), 3.03 (m, 1H), 2.36 (m, 2H), 1.05 (t, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.62 (br. D, 1H, NH), 8.24 (d, 1H), 8.12 (d, 1H), 8.10 (d, 1H), 8:08 ( d, 1H), 7.69 (dd, 1H), 7.66 (m, 2H), 3.87 (q, 2H), 3.03 (m, 1H), 2.36 (m, 2H), 1.05 (t, 3H).

Beispiel No. Example No. I.2-60: I.2-60:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.68 (br. d, 1H, NH), 8.56 (d, 1H), 8.07 (d, 1 H), 7.96 (m, 2H), 7.62 (m, 2H), 7.47 (m, 1 H), 7.00 (m, 2H), 6.93 (m, 3H), 4.62 (m, 1H), 3.68 (q, 2H), 2.67 (dd, 1H), 2.62 (dd, 1H), 0.97 (t, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.68 (br. D, 1H, NH), 8.56 (d, 1H), 8.07 (d, 1 H), 7.96 (m, 2H), 7.62 (m, 2H), 7:47 (m, 1 H), 7.00 (m, 2H), 6.93 (m, 3H), 4.62 (m, 1H), 3.68 (q, 2H), 2.67 (dd, 1H), 2.62 (dd, 1H), 0.97 (t, 3H). Beispiel No.1.2-61: Example No.1.2-61:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.52 (br. d, 1H, NH), 8.20 (d, 1H), 8.16 (d, 1H), 8.05 (d, 1H), 8.03 (m, 1H), 7.62 (m, 2H), 7.57 (m, 2H), 7.01 (m, 3H), 6.91 (m, 2H), 3.68 (m, 1H), 3.14 (s, 3H), 2.60 (m, 2H), 2.32 (m, 2H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8:52 (br. D, 1H, NH), 8.20 (d, 1H), 8.16 (d, 1H), 8:05 (d, 1H), 8:03 ( m, 1H), 7.62 (m, 2H), 7:57 (m, 2H), 7:01 (m, 3H), 6.91 (m, 2H), 3.68 (m, 1H), 3.14 (s, 3H), 2.60 (m , 2H), 2:32 (m, 2H).

Beispiel No. Example No. I.2-62: I.2-62:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.63 (br. d, 1H, NH), 8.22 (d, 1H), 8.17 (d, 1H), 8.08 (d, 1H), 8.00 (d, 1H), 7.66 (m, 3H), 3.76 (q, 2H), 3.43 (m, 1H), 2.25 (m, 2H), 1.22 (m, 2H), 1.02 (t, 3H), 1.00 (m, 1H), 0.59 (d, 3H), 0.32 (d, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.63 (br. D, 1H, NH), 8.22 (d, 1H), 8.17 (d, 1H), 8.08 (d, 1H), 8.00 ( d, 1H), 7.66 (m, 3H), 3.76 (q, 2H), 3:43 (m, 1H), 2.25 (m, 2H), 1.22 (m, 2H), 1:02 (t, 3H), 1.00 (m , 1H), 0:59 (d, 3H), 0:32 (d, 3H).

Beispiel No. Example No. I.2-63: I.2-63:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.66 (br. d, 1H, NH), 8.57 (d, 1H), 8.23 (d, 1H), 8.12 (d, 1H), 8.09 (d, 1H), 7.67 (m, 3H), 4.13 (m, 1H), 3.22 (s, 3H), 3.19 (s, 3H), 2.69 (dd, 1H), 2.53 (dd, 1H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.66 (br. D, 1H, NH), 8:57 (d, 1H), 8.23 (d, 1H), 8.12 (d, 1H), 8:09 ( d, 1H), 7.67 (m, 3H), 4.13 (m, 1H), 3.22 (s, 3H), 3.19 (s, 3H), 2.69 (dd, 1H), 2.53 (dd, 1H).

Beispiel No. Example No. I.2-70: I.2-70:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.62 (d, 1H), 8.20 (d, 1H), 8.09 (m, 2H), 7.95 (br. t, 1H, NH), 7.69 (m, 1H), 7.64 (m, 2H), 2.78 (m, 2H), 2.08 (t, 2H), 1.50 (quint, 2H), 1.30 (s, 9H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.62 (d, 1H), 8.20 (d, 1H), 8:09 (m, 2H), 7.95 (br. T, 1H, NH), 7.69 ( m, 1H), 7.64 (m, 2H), 2.78 (m, 2H), 2:08 (t, 2H), 1:50 (quint, 2H), 1.30 (s, 9H).

Beispiel No.1.2-71: Example No.1.2-71:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.63 (d, 1H), 8.58 (br. t, 1H, NH), 8.21 (d, 1H), 8.10 (d, 1H), 8.08 (d, 1H), 7.72 (m, 1H), 7.66 (m, 1H), 7.61 (m, 1H), 3.78 (q, 2H), 3.72 (d, 2H), 0.91 (t, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.63 (d, 1H), 8:58 (br. T, 1H, NH), 8.21 (d, 1H), 8.10 (d, 1H), 8:08 (d, 1H), 7.72 (m, 1H), 7.66 (m, 1H), 7.61 (m, 1H), 3.78 (q, 2H), 3.72 (d, 2H), 0.91 (t, 3H).

Beispiel No. Example No. I.2-74: I.2-74:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.87 (br. d, 1H, NH), 8.43 (d, 1H), 8.39 (s, 1H), 8.22 (d, 1H), 8.08 (m, 1H), 8.05 (d, 1H), 7.68 (m, 1H), 7.60 (m, 1H), 7.04 (s, 1H), 4.12 (m, 1H), 3.49 (s, 3H), 3.29 (s, 3H), 2.94 (dd, 1H), 2.81 (dd, 1H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.87 (br. D, 1H, NH), 8:43 (d, 1H), 8:39 (s, 1H), 8.22 (d, 1H), 8:08 ( m, 1H), 8:05 (d, 1H), 7.68 (m, 1H), 7.60 (m, 1H), 7:04 (s, 1H), 4.12 (m, 1H), 3:49 (s, 3H), 3.29 (s , 3H), 2.94 (dd, 1H), 2.81 (dd, 1H). Beispiel No. Example No. I.2-75: I.2-75:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.69 (br. d, 1H, NH), 8.59 (d, 1H), 8.22 (d, 1H), 8.11 (d, 1H), 8.07 (d, 1H), 7.71 (m, 1H), 7.64 (m, 1H), 7.60 (m, 1H), 3.42 (m, 1H), 3.10 (s, 3H), 1.84 (m, 1H), 0.72 (d, 3H), 0.63 (d, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.69 (br. D, 1H, NH), 8:59 (d, 1H), 8.22 (d, 1H), 8.11 (d, 1H), 8:07 (d, 1H), 7.71 (m, 1H), 7.64 (m, 1H), 7.60 (m, 1H), 3:42 (m, 1H), 3.10 (s, 3H), 1.84 (m, 1H), 0.72 ( d, 3H), 0.63 (d, 3H).

Beispiel No. Example No. I.2-77: I.2-77:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.57 (br. d, 1H, NH), 8.55 (d, 1H), 8.22 (d, 1H), 8.12 (d, 1H), 8.09 (d, 1H), 7.70 (m, 1H), 7.65 (m, 1H), 7.61 (m, 1H), 3.65 (m, 1H), 3.15 (s, 3H), 1.41 (m, 2H), 1.27 (m, 1H), 0.68 (d, 3H), 0.41 (d, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8:57 (br. D, 1H, NH), 8:55 (d, 1H), 8.22 (d, 1H), 8.12 (d, 1H), 8:09 (d, 1H), 7.70 (m, 1H), 7.65 (m, 1H), 7.61 (m, 1H), 3.65 (m, 1H), 3.15 (s, 3H), 1.41 (m, 2H), 1.27 ( m, 1H), 0.68 (d, 3H), 0:41 (d, 3H).

Beispiel No. Example No. I.2-80: I.2-80:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.81 (br. d, 1H, NH), 8.58 (d, 1H), 8.16 (d, 1H), 8.04 (d, 1H), 7.92 (d, 1H), 7.64 (m, 2H), 7.51 (m, 1H), 7.04 (m, 5H), 3.92 (m, 1H), 3.59 (m, 1H), 3.52 (m, 1H), 2.89 (dd, 1H), 2.77 (dd, 1H), 0.75 (t, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.81 (br. D, 1H, NH), 8:58 (d, 1H), 8.16 (d, 1H), 8:04 (d, 1H), 7.92 (d, 1H), 7.64 (m, 2H), 7:51 (m, 1H), 7:04 (m, 5H), 3.92 (m, 1H), 3:59 (m, 1H), 3:52 (m, 1H), 2.89 ( dd, 1H), 2.77 (dd, 1H), 0.75 (t, 3H).

Beispiel No. Example No. I.2-83: I.2-83:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.64 (br. d, 1H, NH), 8.21 (d, 1H), 8.13 (d, 1H), 8.08 (d, 1H), 8.05 (d, 1H), 7.69 (dd, 1H), 7.64 (m, 2H), 3.37 (m, 1H), 3.12 (s, 3H), 2.36 (dd, 1 H), 2.11 (dd, 1 H), 1.54 (m, 1 H), 1.44 (m, 3H), 1.38 (m, 1 H), 1.16 (m, 1 H), 0.89 (m, 2H), 0.78 (m, 2H), 0.68 (m, 1 H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.64 (br. D, 1H, NH), 8.21 (d, 1H), 8.13 (d, 1H), 8:08 (d, 1H), 8:05 ( d, 1H), 7.69 (dd, 1H), 7.64 (m, 2H), 3:37 (m, 1H), 3.12 (s, 3H), 2:36 (dd, 1 H), 2.11 (dd, 1 H), 1:54 (m, 1 H), 1:44 (m, 3H), 1:38 (m, 1 H), 1.16 (m, 1 H), 0.89 (m, 2H), 0.78 (m, 2H), 0.68 (m, 1 H ).

Beispiel No. Example No. I.2-84: I.2-84:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.64 (br. d, 1H, NH), 8.61 (d, 1H), 8.21 (d, 1H), 8.10 (d, 1H), 8.07 (d, 1H), 7.68 (m, 2H), 7.61 (m, 1H), 6.78 (br. t, 1H), 3.72 (m, 1 H), 3.32 (s, 3H), 2.70 (m, 2H), 1.49 (m, 2H), 1.34 (s, 9H), 1.28 (m, 1 H), 1.16 (m, 1H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.64 (br. D, 1H, NH), 8.61 (d, 1H), 8.21 (d, 1H), 8.10 (d, 1H), 8:07 (d, 1H), 7.68 (m, 2H), 7.61 (m, 1H), 6.78 (br. t, 1H), 3.72 (m, 1 H), 3:32 (s, 3H), 2.70 (m, 2H) , 1:49 (m, 2H), 1:34 (s, 9H), 1.28 (m, 1 H), 1.16 (m, 1H).

Beispiel No. Example No. I.2-86: I.2-86:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.88 (br. d, 1H, NH), 8.62 (d, 1H), 8.22 (d, 1 H), 8.14 (d, 1 H), 8.08 (d, 1 H), 7.68 (m, 2H), 7.63 (m, 1 H), 3.91 (m, 1 H), 3.11 (s, 3H), 2.74 (s, 1H), 2.49 (m, 1H), 2.43 (m, 1H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.88 (br. D, 1H, NH), 8.62 (d, 1H), 8.22 (d, 1 H), 8.14 (d, 1 H) , 8:08 (d, 1 H), 7.68 (m, 2H), 7.63 (m, 1 H), 3.91 (m, 1 H), 3.11 (s, 3H), 2.74 (s, 1H), 2:49 (m, 1H), 2:43 (m, 1H). Beispiel No.1.2-90: Example No.1.2-90:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.80 (br. d, 1H, NH), 8.49 (d, 1H), 8.12 (d, 1H), 8.00 (d, 1H), 7.91 (d, 1H), 7.62 (m, 2H), 7.49 (m, 1H), 6.95 (m, 2H), 6.63 (m, 2H), 3.88 (m, 1H), 3.28 (s, 3H), 2.86 (m, 1H), 2.69 (m, 1H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.80 (br. D, 1H, NH), 8:49 (d, 1H), 8.12 (d, 1H), 8:00 (d, 1H), 7.91 (d, 1H), 7.62 (m, 2H), 7:49 (m, 1H), 6.95 (m, 2H), 6.63 (m, 2H), 3.88 (m, 1H), 3.28 (s, 3H), 2.86 ( m, 1H), 2.69 (m, 1H).

Beispiel No. Example No. I.2-92: I.2-92:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.77 (br. d, 1H, NH), 8.74 (d, 1H), 8.19 (d, 1H), 8.15 (d, 1H), 8.07 (d, 1H), 7.66 (m, 2H), 7.56 (m, 1H), 7.23 (m, 6H), 7.12 (m, 4H), 4.83 (d, 1H), 4.66 (d, 1H), 4.36 (d, 1H), 4.21 (d, 1H), 4.01 (m, 1H), 3.82 (m, 1H), 0.93 (d,3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm), 8.77 (br. D, 1H, NH), 8.74 (d, 1H), 8.19 (d, 1H), 8.15 (d, 1H), 8:07 (d, 1H), 7.66 (m, 2H), 7:56 (m, 1H), 7.23 (m, 6H), 7.12 (m, 4H), 4.83 (d, 1H), 4.66 (d, 1H), 4:36 ( d, 1H), 4.21 (d, 1H), 4.01, (m, 1H), 3.82 (m, 1H), 0.93 (d, 3H).

Beispiel No.1.2-103: Example No.1.2-103:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 9.15 (br. d, 1H, NH), 8.55 (d, 1H), 8.22 (d, 1H), 8.13 (d, 1H), 8.08 (d, 1H), 7.65 (m, 3H), 4.29 (m, 1H), 3.62 (m, 1H), 3.49 (m, 1 H), 2.69 (dd, 1 H), 2.40 (dd, 1 H), 0.93 (t, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 9.15 (br. D, 1H, NH), 8:55 (d, 1H), 8.22 (d, 1H), 8.13 (d, 1H), 8:08 ( d, 1H), 7.65 (m, 3H), 4.29 (m, 1H), 3.62 (m, 1H), 3:49 (m, 1 H), 2.69 (dd, 1 H), 2:40 (dd, 1 H), 0.93 (t, 3H).

Beispiel No.1.2-106: Example No.1.2-106:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 13.70 (br. s, 1H, NH), 8.91 (br. d, 1H, NH), 8.60 (s, 1H), 8.51 (d, 1H), 8.24 (d, 1H), 8.03 (d, 1H), 7.99 (d, 1H), 7.83 (m, 2H), 7.76 (m, 1 H), 7.12 (s, 1 H), 4.20 (m, 1 H), 3.24 (s, 3H), 3.03 (dd, 1 H), 2.92 (dd, 1 H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 13.70 (br. S, 1H, NH), 8.91 (br. D, 1H, NH), 8.60 (s, 1H), 8:51 (d, 1H ), 8.24 (d, 1H), 8:03 (d, 1H), 7.99 (d, 1H), 7.83 (m, 2H), 7.76 (m, 1 H), 7.12 (s, 1 H), 4.20 (m, 1 H), 3.24 (s, 3H), 3:03 (dd, 1 H), 2.92 (dd, 1 H).

Beispiel No.1.2-108: Example No.1.2-108:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.91 (br. d, 1H, NH), 8.55 (d, 1H), 8.15 (m, 2H), 8.08 (d, 1H), 8.02 (d, 1H), 7.97 (d, 1H), 7.66 (m, 1H), 7.62 (m, 1H), 7.49 (m, 1 H), 7.07 (m, 2H), 4.62 (q, 2H), 3.64 (s, 3H), 2.65 (m, 2H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.91 (br. D, 1H, NH), 8:55 (d, 1H), 8.15 (m, 2H), 8:08 (d, 1H), 8:02 ( d, 1H), 7.97 (d, 1H), 7.66 (m, 1H), 7.62 (m, 1H), 7:49 (m, 1 H), 7:07 (m, 2H), 4.62 (q, 2H), 3.64 ( s, 3H), 2.65 (m, 2H).

Beispiel No.1.2-109: Example No.1.2-109:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.86 (br. d, 1H, NH), 8.57 (d, 1H), 8.04 (m, 2H), 7.94 (d, 1H), 7.65 (m, 1H), 7.60 (m, 1H), 7.47 (m, 1H), 7.23 (d, 1H), 7.07 (d, 1H), 6.92 (dd, 1H), 6.74 (dd, 1H), 5.15 (m, 1H), 3.72 (q, 2H), 2.59 (dd, 1H), 2.55 (dd, 1H), 0.99 (t, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.86 (br. D, 1H, NH), 8:57 (d, 1H), 8:04 (m, 2H), 7.94 (d, 1H), 7.65 ( m, 1H), 7.60 (m, 1H), 7:47 (m, 1H), 7.23 (d, 1H), 7:07 (d, 1H), 6.92 (dd, 1H), 6.74 (dd, 1H), 5.15 (m , 1H), 3.72 (q, 2H), 2:59 (dd, 1H), 2:55 (dd, 1H), 0.99 (t, 3H). Beispiel No.1.2-110: Example No.1.2-110:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.71 (br. d, 1H, NH), 8.49 (d, 1H), 8.09 (d, 1H), 7.97 (m, 2H), 7.64 (m, 2H), 7.48 (m, 1H), 7.04 (d, 2H), 6.90 (d, 2H), 4.58 (m, 1H), 3.28 (s, 3H), 2.70 (dd, 1H), 2.62 (dd, 1H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.71 (br. D, 1H, NH), 8:49 (d, 1H), 8:09 (d, 1H), 7.97 (m, 2H), 7.64 ( m, 2H), 7:48 (m, 1H), 7:04 (d, 2H), 6.90 (d, 2H), 4:58 (m, 1H), 3.28 (s, 3H), 2.70 (dd, 1H), 2.62 (dd , 1H).

Beispiel No.1.3-1: Example No.1.3-1:

1 H-NMR (400 MHz, CDCI 3 δ, ppm) 8.58 (m, 1 H), 8.45 (m, 1 H), 8.15 (d, 1 H), 7.92 (d, 1H), 7.72-7.78 (m, 2H), 5.00-5.10 (br. t, 1H, NH), 3.96 (d, 2H). 1 H-NMR (400 MHz, CDCl 3 δ, ppm) 8:58 (m, 1 H), 8:45 (m, 1 H), 8.15 (d, 1 H), 7.92 (d, 1H), 7.72-7.78 (m , 2H), 5:00 to 5:10 (br. t, 1H, NH), 3.96 (d, 2H). Beispiel No. Example No. I.3-24: I.3-24:

1 H-NMR (400 MHz, CDCI3 δ, ppm) 8.62 (d, 1 H), 8.42 (d, 1 H), 8.09 (d, 1 H), 7.89 (d, 1H), 7.73-7.77 (m, 2H), 5.28-5.31 (br. t, 1H, NH), 3.21 (m, 2H), 2.55 (m, 2H). 1 H-NMR (400 MHz, CDCl 3 δ, ppm) 8.62 (d, 1 H), 8:42 (d, 1 H), 8:09 (d, 1 H), 7.89 (d, 1H), 7.73-7.77 (m, 2H), 5:28 to 5:31 (br. t, 1H, NH), 3.21 (m, 2H), 2:55 (m, 2H).

Beispiel No. Example No. I.3-26: I.3-26:

1H-NMR(400MHz, CDCI3 δ, ppm) 8.64 (d, 1H), 8.41 (d, 1H), 8.11 (d, 1H), 7.89 (d, 1H), 7.74-7.78 (m, 2H), 4.96 (br. d, 1H, NH), 3.31 (m, 1H), 2.58 (dd, 1H), 2.50 (dd, 1 H), 1.51 (m, 1 H), 1.47 (m, 1 H), 0.58 (t, 3H). 1H-NMR (400MHz, CDCl 3 δ, ppm) 8.64 (d, 1 H), 8:41 (d, 1H), 8.11 (d, 1H), 7.89 (d, 1 H), 7.74-7.78 (m, 2H), 4.96 ( br. d, 1H, NH), 3.31 (m, 1H), 2:58 (dd, 1H), 2:50 (dd, 1 H), 1:51 (m, 1 H), 1:47 (m, 1 H), 0:58 (t , 3H).

Beispiel No. Example No. I.3-28: I.3-28:

1H-NMR (400 MHz, CDCI3 δ, ppm) 8.66 (d, 1 H), 8.38 (d, 1 H), 8.12 (d, 1 H), 7.88 (d, 1H), 7.70 (m, 2H), 5.55 (br. d, 1H, NH), 3.87 (q, 2H), 3.24 (m, 1H), 2.33 (dd, 1H), 2.18 (dd, 1H), 1.78 (m, 1H), 1.12 (t, 3H), 0.73 (d, 3H), 0.70 (d, 3H). 1H-NMR (400 MHz, CDCl 3 δ, ppm) 8.66 (d, 1 H), 8:38 (d, 1 H), 8.12 (d, 1 H), 7.88 (d, 1H), 7.70 (m, 2H), 5:55 (br. d, 1H, NH), 3.87 (q, 2H), 3.24 (m, 1H), 2:33 (dd, 1H), 2.18 (dd, 1H), 1.78 (m, 1H), 1.12 (t, 3H), 0.73 (d, 3H), 0.70 (d, 3H).

Beispiel No. Example No. I.3-34: I.3-34:

1H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.67 (d, 1 H), 8.32 (d, 1 H), 8.27 (br. t, 1 H, NH), 8.07 (d, 1H), 8.02 (d, 1H), 7.82 (m, 2H), 3.82 (q, 2H), 3.03 (m, 2H), 2.35 (t, 2H), 1.03 (t, 3H). 1H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.67 (d, 1 H), 8:32 (d, 1 H), 8.27 (br. T, 1 H, NH), 8:07 (d, 1H); 8:02 (d, 1H), 7.82 (m, 2H), 3.82 (q, 2H), 3:03 (m, 2H), 2:35 (t, 2H), 1:03 (t, 3H).

Beispiel No.1.3-41: Example No.1.3-41:

1H-NMR(400MHz, CDCI3 δ, ppm) 8.62 (m, 1H), 8.38 (m, 1H), 8.14 (d, 1H), 7.87 (d, 1H), 7.68-7.74 (m, 2H), 5.50 (br. d, 1H, NH), 3.85-3.98 (m, 2H), 3.62-3.70 (m, 1H), 2.30 (d, 2H), 1.12-1.18 (t, 3H), 1.08-1.10 (d, 3H). 1H-NMR (400MHz, CDCl 3 δ, ppm) 8.62 (m, 1H), 8:38 (m, 1H), 8.14 (d, 1H), 7.87 (d, 1H), 7.68-7.74 (m, 2H), 5.50 ( br. d, 1H, NH), 3.85-3.98 (m, 2H), 3.62-3.70 (m, 1H), 2.30 (d, 2H), 1:12 to 1:18 (t, 3H), 1:08 to 1:10 (d, 3H ). Beispiel No.1.3-42: Example No.1.3-42:

1 H-NMR(400MHz, CDC δ, ppm) 8.60 (m, 1H), 8.36 (m, 1H), 8.14 (d, 1H), 7.86- 7.90 (d, 1H), 7.70 (m, 2H), 5.40-5.45 (br. d, 1H, NH), 3.65-3.72 (m, 1H), 2.45 (d, 2H), 1.10 (d,3H). 1 H-NMR (400MHz, CDC δ, ppm) 8.60 (m, 1H), 8:36 (m, 1H), 8.14 (d, 1H), 7.86- 7.90 (d, 1H), 7.70 (m, 2H), 5:40 -5.45 (br. d, 1H, NH), 3.65-3.72 (m, 1H), 2:45 (d, 2H), 1.10 (d, 3H).

Beispiel No. Example No. I.3-60: I.3-60:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.83 (br. d, 1H, NH), 8.57 (d, 1H), 8.14 (d, 1H), 7.83 (m, 2H), 7.74 (m, 2H), 6.91 (m, 3H), 6.84 (m, 2H), 4.58 (m, 1H), 3.69 (q, 2H), 2.67 (dd, 1H), 2.57 (dd, 1H), 0.96 (t, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.83 (br. D, 1H, NH), 8.57 (d, 1H), 8.14 (d, 1H), 7.83 (m, 2H), 7.74 ( m, 2H), 6.91 (m, 3H), 6.84 (m, 2H), 4.58 (m, 1H), 3.69 (q, 2H), 2.67 (dd, 1H), 2.57 (dd, 1H), 0.96 (t , 3H).

Beispiel No.1.3-61: Example No.1.3-61:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.54 (d, 1H), 8.35 (d, 1H), 8.23 (br. d, 1H, NH), 7.92 (m, 2H), 7.75 (m, 2H), 6.88 (m, 5H), 3.68 (m, 1H), 3.22 (s, 3H), 2.60 (m, 2H), 2.40 (m, 2H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8:54 (d, 1H), 8:35 (d, 1H), 8.23 (br. D, 1H, NH), 7.92 (m, 2H), 7.75 ( m, 2H), 6.88 (m, 5H), 3.68 (m, 1H), 3.22 (s, 3H), 2.60 (m, 2H), 2:40 (m, 2H).

Beispiel No. Example No. I.3-62: I.3-62:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.67 (d, 1H), 8.31 (d, 1H), 8.20 (br. d, 1H, NH), 8.06 (m, 2H), 7.82 (m, 2H), 3.68 (m, 2H), 3.40 (m, 1H), 2.23 (m, 2H), 1.22 (m, 2H), 1.01 (m, 1 H), 0.97 (t, 3H), 0.60 (d, 3H), 0.36 (d, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.67 (d, 1H), 8.31 (d, 1H), 8.20 (br. D, 1H, NH), 8:06 (m, 2H), 7.82 ( m, 2H), 3.68 (m, 2H), 3:40 (m, 1H), 2.23 (m, 2H), 1.22 (m, 2H), 1:01 (m, 1 H), 0.97 (t, 3H), 0.60 ( d, 3H), 0:36 (d, 3H).

Beispiel No. Example No. I.3-63: I.3-63:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 9.01 (br. d, 1H, NH), 8.63 (d, 1H), 8.32 (d, 1H), 8.07 (d, 1H), 8.02 (d, 1H), 7.82 (m, 2H), 4.13 (m, 1H), 3.24 (s, 3H), 3.22 (s, 3H), 2.68 (dd, 1H), 2.55 (dd, 1H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 9:01 (br. D, 1H, NH), 8.63 (d, 1H), 8:32 (d, 1H), 8:07 (d, 1H), 8:02 ( d, 1H), 7.82 (m, 2H), 4.13 (m, 1H), 3.24 (s, 3H), 3.22 (s, 3H), 2.68 (dd, 1H), 2:55 (dd, 1H).

Beispiel No. Example No. I.3-70: I.3-70:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.69 (d, 1H), 8.31 (m, 1H), 8.10 (br. t, 1H, NH), 8.06 (d, 1H), 7.99 (d, 1H), 7.82 (m, 2H), 2.79 (m, 2H), 2.04 (t, 2H), 1.49 (quint, 2H), 1.29 (s, 9H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.69 (d, 1H), 8.31 (m, 1H), 8.10 (br. T, 1H, NH), 8:06 (d, 1H), 7.99 ( d, 1H), 7.82 (m, 2H), 2.79 (m, 2H), 2:04 (t, 2H), 1:49 (quint, 2H), 1.29 (s, 9H). Beispiel No.1.3-71: Example No.1.3-71:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.73 (d, 1H), 8.69 (br. t, 1H, NH), 8.32 (m, 1H), 8.03 (d, 1H), 8.00 (d, 1H), 7.82 (m, 2H), 3.78 (q, 2H), 3.75 (d, 2H), 0.91 (t, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.73 (d, 1H), 8.69 (br. T, 1H, NH), 8:32 (m, 1H), 8:03 (d, 1H), 8:00 ( d, 1H), 7.82 (m, 2H), 3.78 (q, 2H), 3.75 (d, 2H), 0.91 (t, 3H). Beispiel No. Example No. I.3-72: I.3-72:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.72 (d, 1H), 8.63 (br. s, 1H, NH), 8.32 (m, 1H), 8.05 (d, 1H), 8.00 (d, 1H), 7.83 (m, 2H), 3.37 (s, 3H), 1.27 (s, 2H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.72 (d, 1H), 8.63 (br. S, 1H, NH), 8:32 (m, 1H), 8:05 (d, 1H), 8:00 ( d, 1H), 7.83 (m, 2H), 3:37 (s, 3H), 1.27 (s, 2H).

Beispiel No. Example No. I.3-73: I.3-73:

1H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.79 (br. d, 1H, NH), 8.73 (d, 1H), 8.31 (m, 1H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.79 (br. D, 1H, NH), 8.73 (d, 1H), 8.31 (m,

1H), 8.06 (d, 1H), 8.00 (d, 1H), 7.84 (m, 2H), 3.70 (m, 1H), 3.18 (s, 3H), 1.48 (q, 2H), 1.13 (m, 1H), 1.06 (m, 1H), 0.60 (t, 3H). 1H), 8:06 (d, 1H), 8:00 (d, 1H), 7.84 (m, 2H), 3.70 (m, 1H), 3.18 (s, 3H), 1:48 (q, 2H), 1.13 (m, 1H ), 1:06 (m, 1H), 0.60 (t, 3H).

Beispiel No. Example No. I.3-74: I.3-74:

1H-NMR (400 MHz, d 6 -DMSO δ, ppm) 9.01 (br. d, 1H, NH), 8.93 (d, 1H), 8.53 (s, 1H-NMR (400 MHz, d 6 -DMSO δ, ppm) 9:01 (br. D, 1H, NH), 8.93 (d, 1H), 8:53 (s,

1H), 8.32 (d, 1H), 8.16 (d, 1H), 8.04 (d, 1H), 7.78 (m, 1H), 7.63 (m, 1H), 7.13 (s, 1H), 4.15 (m, 1H), 3.54 (s, 3H), 3.28 (s, 3H), 2.97 (dd, 1H), 2.83 (dd, 1H). 1H), 8:32 (d, 1H), 8.16 (d, 1H), 8:04 (d, 1H), 7.78 (m, 1H), 7.63 (m, 1H), 7.13 (s, 1H), 4.15 (m, 1H ), 3:54 (s, 3H), 3.28 (s, 3H), 2.97 (dd, 1H), 2.83 (dd, 1H).

Beispiel No. Example No. I.3-75: I.3-75:

1H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.78 (d, 1H), 8.62 (br. d, 1H, NH), 8.31 (m, 1H), 8.04 (d, 1H), 7.99 (d, 1H), 7.82 (m, 2H), 3.44 (m, 1H), 3.12 (s, 3H), 1.85 (m, 1H), 0.72 (d, 3H), 0.64 (d, 3H). 1H-NMR (400 MHz, d 6 DMSO δ, ppm) 8.78 (d, 1H), 8.62 (br. D, 1H, NH), 8.31 (m, 1H), 8:04 (d, 1H), 7.99 (d , 1H), 7.82 (m, 2H), 3:44 (m, 1H), 3.12 (s, 3H), 1.85 (m, 1H), 0.72 (d, 3H), 0.64 (d, 3H).

Beispiel No. Example No. I.3-76: I.3-76:

1H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.80 (br. d, 1 H, NH), 8.72 (d, 1 H), 8.33 (m, 1H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.80 (br. D, 1 H, NH), 8.72 (d, 1 H), 8:33 (m,

1H), 8.07 (d, 1H), 8.00 (d, 1H), 7.83 (m, 2H), 3.90 (m, 1H), 3.18 (s, 3H), 1.15 (d, 3H). 1H), 8:07 (d, 1H), 8:00 (d, 1H), 7.83 (m, 2H), 3.90 (m, 1H), 3.18 (s, 3H), 1.15 (d, 3H).

Beispiel No. Example No. I.3-77: I.3-77:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.81 (br. d, 1H, NH), 8.71 (d, 1H), 8.32 (m, 1H), 8.06 (d, 1H), 8.00 (d, 1H), 7.84 (m, 2H), 3.69 (m, 1H), 3.15 (s, 3H), 1.42 (m, 2H), 1.29 (m, 1H), 0.70 (d, 3H), 0.46 (d, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.81 (br. D, 1H, NH), 8.71 (d, 1H), 8:32 (m, 1H), 8:06 (d, 1H), 8:00 ( d, 1H), 7.84 (m, 2H), 3.69 (m, 1H), 3.15 (s, 3H), 1:42 (m, 2H), 1.29 (m, 1H), 0.70 (d, 3H), 0:46 (d , 3H). Beispiel No.1.3-79: Example No.1.3-79:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.85 (br. d, 1H, NH), 8.71 (d, 1H), 8.32 (m, 1H), 8.07 (d, 1H), 8.00 (d, 1H), 7.85 (m, 2H), 3.88 (m, 1H), 3.28 (s, 3H), 2.23 (m, 1H), 2.04 (m, 1H), 1.75 (s, 3H), 1.71 (m, 2H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.85 (br. D, 1H, NH), 8.71 (d, 1H), 8:32 (m, 1H), 8:07 (d, 1H), 8:00 ( d, 1H), 7.85 (m, 2H), 3.88 (m, 1H), 3.28 (s, 3H), 2.23 (m, 1H), 2:04 (m, 1H), 1.75 (s, 3H), 1.71 (m , 2H).

Beispiel No. Example No. I.3-80: I.3-80:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.94 (br. d, 1H, NH), 8.61 (d, 1H), 8.24 (d, 1H), 7.91 (d, 1H), 7.79 (d, 1H), 7.75 (m, 2H), 6.95 (m, 5H), 3.94 (m, 1H), 3.68 (q, 2H), 2.91 (dd, 1H), 2.72 (dd, 1H), 0.82 (t, 3H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.94 (br. D, 1H, NH), 8.61 (d, 1H), 8.24 (d, 1H), 7.91 (d, 1H), 7.79 ( d, 1H), 7.75 (m, 2H), 6.95 (m, 5H), 3.94 (m, 1H), 3.68 (q, 2H), 2.91 (dd, 1H), 2.72 (dd, 1H), 0.82 (t , 3H).

Beispiel No. Example No. I.3-82: I.3-82:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.98 (br. d, 1H, NH), 8.43 (d, 1H), 8.39 (s, 1H), 8.26 (m, 2H), 7.95 (d, 1H), 7.82 (d, 1H), 7.79 (m, 2H), 7.63 (m, 1H), 7.19 (m, 1H), 4.15 (m, 1H), 3.38 (s, 3H), 3.11 (dd, 1H), 2.73 (dd, 1H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.98 (br. D, 1H, NH), 8:43 (d, 1H), 8:39 (s, 1H), 8.26 (m, 2H), 7.95 ( d, 1H), 7.82 (d, 1H), 7.79 (m, 2H), 7.63 (m, 1H), 7.19 (m, 1H), 4.15 (m, 1H), 3:38 (s, 3H), 3.11 (dd , 1H), 2.73 (dd, 1H).

Beispiel No. Example No. I.3-83: I.3-83:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.68 (d, 1H), 8.30 (d, 1H), 8.22 (br. d, 1H, NH), 8.05 (d, 1H), 8.01 (d, 1H), 7.81 (m, 2H), 3.34 (m, 1H), 3.05 (s, 3H), 2.36 (dd, 1H), 2.09 (dd, 1H), 1.53 (m, 1H), 1.48 (m, 2H), 1.41 (m, 1H), 1.19 (m, 1H), 0.91 (m, 2H), 0.76-0.89 (m, 3H), 0.69 (m, 1 H). 1 H-NMR (400 MHz, d 6 DMSO δ, ppm) 8.68 (d, 1 H) 8.30 (d, 1H), 8.22 (br. D, 1H, NH), 8:05 (d, 1 H), 8:01 ( d, 1H), 7.81 (m, 2H), 3:34 (m, 1H), 3:05 (s, 3H), 2:36 (dd, 1H), 2:09 (dd, 1H), 1:53 (m, 1H), 1:48 (m , 2H), 1:41 (m, 1H), 1.19 (m, 1H), 0.91 (m, 2H), 0.76-0.89 (m, 3H), 0.69 (m, 1 H).

Beispiel No. Example No. I.3-84: I.3-84:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.76 (br. d, 1H, NH), 8.71 (m, 1H), 8.31 (m, 1H), 8.04 (d, 1H), 7.99 (d, 1H), 7.82 (m, 2H), 6.66 (br. t, 1H, NH), 4.07 (m, 1H), 3.74 (m, 1H), 3.10 (s, 3H), 2.72 (m, 2H), 1.52 (m, 2H), 1.34 (s, 9H), 1.19 (m, 1H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.76 (br. D, 1H, NH), 8.71 (m, 1H), 8.31 (m, 1H), 8:04 (d, 1H), 7.99 ( d, 1H), 7.82 (m, 2H), 6.66 (br. t, 1H, NH), 4:07 (m, 1H), 3.74 (m, 1H), 3.10 (s, 3H), 2.72 (m, 2H) , 1:52 (m, 2H), 1:34 (s, 9H), 1.19 (m, 1H).

Beispiel No. Example No. I.3-86: I.3-86:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.99 (br. d, 1H, NH), 8.70 (m, 1H), 8.33 (m, 1H), 8.06 (d, 1H), 8.04 (d, 1H), 7.82 (m, 2H), 3.94 (m, 1H), 3.16 (s, 3H), 2.71 (s, 1H), 2.47 (m, 2H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.99 (br. D, 1H, NH), 8.70 (m, 1H), 8:33 (m, 1H), 8:06 (d, 1H), 8:04 ( d, 1H), 7.82 (m, 2H), 3.94 (m, 1H), 3.16 (s, 3H), 2.71 (s, 1H), 2:47 (m, 2H). Beispiel No.1.3-90: Example No.1.3-90:

1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.92 (br. d, 1H, NH), 8.49 (d, 1H), 8.24 (d, 1H), 7.89 (d, 1H), 7.79 (d, 1H), 7.77 (m, 1H), 7.70 (m, 1H), 6.88 (m, 2H), 6.51 (m, 2H), 3.92 (m, 1H), 3.39 (s, 3H), 2.86 (dd, 1H), 2.63 (dd, 1H). 1 H-NMR (400 MHz, d 6 -DMSO δ, ppm) 8.92 (br. D, 1H, NH), 8.49 (d, 1H), 8.24 (d, 1H), 7.89 (d, 1H), 7.79 ( d, 1H), 7.77 (m, 1H), 7.70 (m, 1H), 6.88 (m, 2H), 6:51 (m, 2H), 3.92 (m, 1H), 3:39 (s, 3H), 2.86 (dd , 1H), 2.63 (dd, 1H).

Beispiel No.1.3-91: Example No.1.3-91: