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The present invention features methods and formulations or compositions, such as a naturaceutical formulation, for treating and preventing headaches, and particularly migraine headaches, as well as methods and formulations for treating the conditions and symptoms often associated with migraine headaches. The naturaceutical formulations comprise an identified amount of a processed Morinda citrifolia product by weight, and the method comprises the prophylactic administration of the processed Morinda citrifolia product-based naturaceutical formulation in a safe, pre-determined or identified amount for a safe, pre-determined frequency, for a safe, pre-determined duration of time.

Inventors: Stephen Story, Claude Jarakae Jensen, Afa Kehaati Palu
Current U.S. Classification: 424/765; 424/777
International Classification: A61K035/78

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Referenced by

Citing PatentFiling dateIssue dateOriginal AssigneeTitle
US7442395Jan 26, 2006Oct 28, 2008Tahitian Noni International, Inc.Formulation for treating candidiasis using Morinda citrifolia
US8025910May 10, 2007Sep 27, 2011Tahitian Noni International, Inc.Method and composition for administering bioactive compounds derived from Morinda citrifolia

Claims

1. A naturaceutical formulation for treating headaches and its associated symptoms in mammals, said naturaceutical formulation comprising a processed Morinda citrifolia product;

2. The formulation of claim 1, wherein said processed Morinda citrifolia product comprises Morinda citrifolia fruit juice.

3. The formulation of claim 1, wherein said processed Morinda citrifolia product comprises Morinda citrifolia puree juice.

4. The formulation of claim 1, wherein said processed Morinda citrifolia product comprises Morinda citrifolia puree juice concentrate.

5. The formulation of claim 1, wherein said processed Morinda citrifolia product comprises Morinda citrifolia fruit juice concentrate.

6. The formulation of claim 1, wherein said processed Morinda citrifolia product comprises Morinda citrifolia dietary fiber.

7. The formulation of claim 1, wherein said processed Morinda citrifolia product of said naturaceutical formulation further comprises an active ingredient Quercetin present in an amount between about 0.1 and 10 percent by weight.

8. The formulation of claim 1, wherein said processed Morinda citrifolia product is present in an amount between about 0.01 and 100 percent by weight.

9. The formulation of claim 7, wherein said processed Morinda citrifolia product further comprises Rutin as an additional active ingredient that synergistically works with said Quercetin to treat said migraine headaches and its associated symptoms.

10. The formulation of claim 9, wherein said Rutin is present in an amount between about 0.1 and 10 percent by weight.

11. The formulation of claim 1, wherein said naturaceutical is administered orally.

12. The formulation of claim 1, wherein said naturaceutical is administered transdermally to said infected area.

13. The formulation of claim 1, wherein said naturaceutical is administered intravenously.

14. The formulation of claim 1, wherein said naturaceutical is administered systemically.

15. A method of treating headaches and its associated symptoms in mammals, said method comprising the steps of:

obtaining a naturaceutical formulation comprising a processed Morinda citrifolia product; and
orally administering a safe, pre-determined amount of said naturaceutical formulation for safe, pre-determined frequency for a safe, pre-determined duration.

16. The method of claim 15, wherein said processed Morinda citrifolia product comprises Morinda citrifolia fruit juice.

17. The method of claim 15, wherein said processed Morinda citrifolia product comprises Morinda citrifolia puree.

18. The method of claim 15, wherein said processed Morinda citrifolia product comprises Morinda citrifolia puree juice.

19. The method of claim 15, further comprising the step of supplementing said step of orally administering said food product with a prescribed migraine medication formulated for the treatment of migraine headaches, said migraine medicine administered concurrently with said naturaceutical.

20. The method of claim 15, wherein said safe, pre-determined amount is between about one teaspoon and about two ounces.

21. The method of claim 15, wherein said safe, pre-determined frequency comprises at least two times per day on an empty stomach.

22. The method of claim 15, wherein said safe, pre-determined duration of time comprises at least three consecutive days.

23. A method for preventing the onset of a future headache in a mammal, said formulation comprising:

obtaining a naturaceutical formulation comprising a processed Morinda citrifolia product; and
orally administering to said mammal between about 1 teaspoon and 2 ounces of said naturaceutical formulation at least twice daily on an empty stomach each day.

24. A method for treating a migraine headache, said method comprising the steps of:

orally administering at least one ounce of a naturaceutical formulation comprising processed Morinda citrifolia fruit juice on an empty stomach in the morning;
orally administering at least one ounce of said naturaceutical formulation prior to sleeping at night; and
repeating said steps of orally administering for continued consecutive days.

25. The method of claim 24, wherein said naturaceutical formulation comprises:

processed Morinda citrifolia fruit juice present in an amount by weight of about 100 percent.

26. The method of claim 24, wherein said naturaceutical formulation comprises:

processed Morinda citrifolia fruit juice present in an amount by weight between about 85-99.99 percent; and
water present in an amount by weight between about 0.1-15 percent.

27. The method of claim 24, wherein said naturaceutical formulation comprises:

processed Morinda citrifolia fruit juice present in an amount by weight between about 85-99.99 percent; and
non-Morinda citrifolia-based fruit juices present in an amount by weight between about 0.1-15 percent.

28. The method of claim 24, wherein said naturaceutical formulation comprises:

processed Morinda citrifolia fruit juice present in an amount by weight between about 50-90 percent;
water present in an amount by weight between about 0.1-50 percent; and
non-Morinda citrifolia-based fruit juices present in an amount between about 0.1-30 percent.

29. A method for reducing cerebral vasoconstriction and subsequent vasodilatation contributing to a migraine headache, said method comprising the steps of:

administering to a patient a naturaceutical formulation comprising a processed Morinda citrifolia product.

30. The method of claim 29, wherein said step of administering comprises orally ingesting at least one ounce of said naturaceutical formulation twice daily on an empty stomach.

31. The method of claim 29, wherein said step of administering comprises intravenous injection of said naturaceutical formulation.

32. The method of claim 1, wherein said step of administering comprises transdermal delivery of said naturaceutical formulation.

33. The method of claim 29, wherein said processed Morinda citrifolia product comprises Morinda citrifolia fruit juice.

34. The formulation of claim 29, wherein said processed Morinda citrifolia product comprises Morinda citrifolia puree juice.

35. The formulation of claim 29, wherein said processed Morinda citrifolia product comprises Morinda citrifolia puree juice concentrate.

36. The method of claim 29, wherein said processed Morinda citrifolia product comprises Morinda citrifolia fruit juice concentrate.

37. The method of claim 29, wherein said processed Morinda citrifolia product comprises Morinda citrifolia dietary fiber.

38. A method for normalizing or improving the flow of blood within the cerebrum during a migraine attack, said method comprising the steps of:

reducing vasoconstriction in said cerebrum through the prophylactic administration of a naturaceutical composition comprising a processed Morinda citrifolia product present in an amount by weight between 0.1 and 100 percent.

39. The method of claim 38, further comprising the step of reducing vasodilatation through the prophylactic administration of said naturaceutical composition.

40. A method for treating prodromal neurological signs and symptoms associated with a headache comprising the steps of:

orally administering at least one ounce of a naturaceutical formulation comprising a processed Morinda citrifolia product on an empty stomach in the morning;
orally administering at least one ounce of said naturaceutical formulation prior to sleeping at night; and
repeating said steps of orally administering for continued consecutive days.

41. A method of maintaining and enhancing serotonin levels in the body of a mammal for the purpose of treating migraine headaches, said method comprising the steps of:

orally administering at least one ounce of a naturaceutical formulation comprising a processed Morinda citrifolia product on an empty stomach in the morning;
orally administering at least one ounce of said naturaceutical formulation prior to sleeping at night; and
repeating said steps of orally administering for continued consecutive days.

42. A method for inhibiting the drug breakdown functions of cytochrome enzymes for the purpose of treating a migraine headache, said method comprising the steps of:

administering a migraine medication to a patient;
administering a naturaceutical to said patient concurrently with said migraine medication, said naturaceutical comprising a processed Morinda citrifolia product that reduces the breaking down or metabolizing of said migraine medication by inhibiting the medication breakdown functions of said cytochrome enzymes, thus increasing the efficacy of said migraine medication, said processed Morinda citrifolia product present in an amount by weight between 20 and 100 percent.

43. The method of claim 42, wherein said migraine medication is selected from the type consisting of symptomatic, abortive, and preventative.

44. The method of claim 42, wherein said processed Morinda citrifolia product comprises processed Morinda citrifolia fruit juice.

45. The method of claim 42, wherein said processed Morinda citrifolia product comprises processed Morinda citrifolia puree juice.

46. The method of claim 42, wherein said processed Morinda citrifolia product comprises processed Morinda citrifolia dietary fiber.

47. The method of claim 42, wherein said processed Morinda citrifolia product comprises processed Morinda citrifolia fruit juice concentrate.

48. The method of claim 42, wherein said processed Morinda citrifolia product comprises processed Morinda citrifolia puree juice concentrate.