Search Images Maps Play YouTube News Gmail Drive More »
Advanced Patent Search | Web History | Sign in

Patents

The present invention features a method for inhibiting, reducing, and/or preventing mutagenesis, or inducing antimutagenesis activity, through the prophylactic administration of a naturaceutical formulation comprising at least one of a processed Morinda citrifolia product. The present invention seeks to provide a natural composition, or naturaceutical, for the purpose of inhibiting both naturally occurring or spontaneous mutagenesis, as well as environmentally induced mutagenesis, within the body of a mammal.

Referenced by

Citing PatentFiling dateIssue dateOriginal AssigneeTitle
US8025910May 10, 2007Sep 27, 2011Tahitian Noni International, Inc.Method and composition for administering bioactive compounds derived from Morinda citrifolia

Claims

1. A method for inhibiting and preventing mutagenesis in mammals, said method comprising the steps of:

introducing a naturaceutical composition into the body of said mammal, said naturaceutical composition comprising a processed Morinda citrifolia product present in an amount between about 0.01 and 100 percent by weight, said processed Morinda citrifolia product comprising the active ingredient Quercetin; and
administering a safe, pre-determined amount of said naturaceutical composition for a safe, pre-determined duration of time.

2. The method of claim 1, wherein said Quercetin is present in an amount between about 0.1 and 10 percent by weight.

3. The method of claim 1, wherein said processed Morinda citrifolia product is Morinda citrifolia fruit juice.

4. The method of claim 1, wherein said processed Morinda citrifolia product is Morinda citrifolia oil extract.

5. The method of claim 1, wherein said processed Morinda citrifolia product is Morinda citrifolia dietary fiber.

6. The method of claim 1, wherein said processed Morinda citrifolia product is Morinda citrifolia puree juice.

7. The method of claim 1, wherein said processed Morinda citrifolia product is Morinda citrifolia puree.

8. The method of claim 1, wherein said processed Morinda citrifolia product further comprises Rutin as an additional active ingredient that synergistically works with said Quercetin to inhibit and prevent mutagenesis.

9. The method of claim 8, wherein said Rutin is present in an amount between about 0.1 and 10 percent by weight.

10. The method of claim 1, wherein said composition is administered orally.

11. The method of claim 1, wherein said composition is administered transdermally to said infected area.

12. The method of claim 1, wherein said composition is administered by injection.

13. The method of claim 1, wherein said composition is administered intravenously.

14. The method of claim 1, wherein said composition is administered systemically.

15. The method of claim 1, wherein said processed Morinda citrifolia product comprises processed Morinda citrifolia fruit juice concentrate.

16. The method of claim 1, wherein said processed Morinda citrifolia product comprises processed Morinda citrifolia puree juice concentrate.

17. The method of claim 1, wherein said naturaceutical composition functions to block DNA adduct formation.

18. A method for inducing antimutagenesis activity within mammals and repairing existing DNA damage, said method comprising the steps of:

adding a processed Morinda citrifolia product to an alcohol-based solution;
isolating and extracting an active ingredient of said processed Morinda citrifolia product from said solution;
introducing, internally, said extracted active ingredient into the body of said mammal, said active ingredient of said Morinda citrifolia functions to inhibit and block DNA adduct formation, thus inducing antimutagenesis activity within said mammal.

19. The method of claim 18, wherein said processed Morinda citrifolia product comprises processed Morinda citrifolia fruit juice.

20. The method of claim 18, wherein said processed Morinda citrifolia product comprises processed Morinda citrifolia puree.

21. The method of claim 18, wherein said alcohol-based solution is selected from the group consisting essentially of methanol, ethanol, and ethyl acetate, and other alcohol-based derivatives.

22. The method of claim 18, wherein said active ingredient is Quercetin.

23. The method of claim 22, wherein said active ingredient is Rutin that synergistically works with said Quercetin to inhibit and prevent growth of said cancerous cells in said colon region.

24. The method of claim 18, wherein said step of introducing, internally, said extracted active ingredient into said body of said mammal comprises orally administering two ounces of a food product comprising said active ingredient to said mammal twice daily each day on an empty stomach.

25. The method of claim 18, wherein said step of introducing, internally, said extracted active ingredient into said body of said mammal comprises applying a topical composition comprising said active ingredient to the epidermis of said mammal.

26. A method for inducing antimutagenesis activity within mammals, said method comprising the steps of:

orally administering at least one ounce of a naturaceutical formulation comprising a processed Morinda citrifolia product on an empty stomach in the morning; and
orally administering to said mammal at least one ounce of said naturaceutical formulation on an empty stomach prior to sleeping at night.

27. The method of claim 26, wherein said naturaceutical formulation comprises:

processed Morinda citrifolia fruit juice present in an amount by weight of about 100 percent.

28. The method of claim 26, wherein said naturaceutical formulation comprises:

processed Morinda citrifolia fruit juice present in an amount by weight between about 85-99.99 percent; and
water present in an amount by weight between about 0.1-15 percent.

29. The method of claim 26, wherein said naturaceutical formulation comprises:

processed Morinda citrifolia fruit juice present in an amount by weight between about 85-99.99 percent; and
non-Morinda citrifolia-based fruit juices present in an amount by weight between about 0.1-15 percent.

30. The method of claim 26, wherein said naturaceutical formulation comprises:

processed Morinda citrifolia fruit juice present in an amount by weight between about 50-90 percent;
water present in an amount by weight between about 0.1-50 percent; and
non-Morinda citrifolia-based fruit juices present in an amount between about 0.1-30 percent.

31. The method of claim 26, wherein said naturaceutical formulation comprises:

processed Morinda citrifolia puree juice present in an amount by weight of about 100 percent.

32. The method of claim 26, wherein said naturaceutical formulation comprises:

processed Morinda citrifolia puree juice present in an amount by weight between about 85-99.99 percent; and
water present in an amount by weight between about 0.1-15 percent.

33. The method of claim 26, wherein said naturaceutical formulation comprises:

processed Morinda citrifolia puree juice present in an amount by weight between about 85-99.99 percent; and
non-Morinda citrifolia-based fruit juices present in an amount by weight between about 0.1-15 percent.

34. The method of claim 26, wherein said naturaceutical formulation comprises:

processed Morinda citrifolia puree juice present in an amount by weight between about 50-90 percent;
water present in an amount by weight between about 0.1-50 percent; and
non-Morinda citrifolia-based fruit juices present in an amount between about 0.1-30 percent.

35. The method of claim 26, wherein said step of orally administering comprises orally administering two ounces of said naturaceutical formulation.

36. A method for inhibiting and preventing mutagenesis in mammals, said method comprising the steps of:

orally administering at least one ounce of a naturaceutical formulation comprising a processed Morinda citrifolia product in the morning on an empty stomach;
orally administering at least one ounce of said naturaceutical formulation prior to sleeping at night;
repeating said steps of orally administering said naturaceutical for a sustained safe, pre-determined duration of time to effectuate antimutagenesis activity within said mammal.

37. The method of claim 36, wherein said naturaceutical formulation comprises:

processed Morinda citrifolia fruit juice present in an amount between about 100 percent by weight.

38. The method of claim 36, wherein said naturaceutical formulation comprises:

processed Morinda citrifolia fruit juice present in an amount between about 85-99.99 percent by weight; and
water present in an amount between about 0.1-15 percent by weight.

39. The method of claim 36, wherein said naturaceutical formulation comprises:

processed Morinda citrifolia fruit juice present in an amount between about 85-99.99 percent by weight; and
non-Morinda citrifolia-based fruit juices present in an amount between about 0.1-15 percent by weight.

40. The method of claim 36, wherein said naturaceutical formulation comprises:

processed Morinda citrifolia fruit juice present in an amount between about 50-90 percent by weight;
water present in an amount between about 0.1-50 percent by weight; and
non-Morinda citrifolia-based fruit juices present in an amount between about 0.1-30 percent by weight.

41. The method of claim 36, wherein said naturaceutical formulation comprises:

processed Morinda citrifolia puree juice present in an amount of about 100 percent by weight.

42. The method of claim 36, wherein said naturaceutical formulation comprises:

processed Morinda citrifolia puree juice present in an amount between about 85-99.99 percent by weight; and
water present in an amount between about 0.1-15 percent by weight.

43. The method of claim 36, wherein said naturaceutical formulation comprises:

processed Morinda citrifolia puree juice present in an amount between about 85-99.99 percent by weight; and
non-Morinda citrifolia-based fruit juices present in an amount between about 0.1-15 percent by weight.

44. The method of claim 36, wherein said naturaceutical formulation comprises:

processed Morinda citrifolia puree juice present in an amount between about 50-90 percent by weight;
water present in an amount between about 0.1-50 percent by weight; and
non-Morinda citrifolia-based fruit juices present in an amount between about 0.1-30 percent by weight.

45. The method of claim 36, wherein said step of orally administering comprises orally administering two ounces of said naturaceutical formulation twice daily each day for a safe, pre-determined duration of time.

46. A method for inhibiting and preventing mutagenesis in mammals, said method comprising the steps of:

administering a naturaceutical composition to a mammal, said naturaceutical composition comprising:
at least one processed Morinda citrifolia product present in an amount between about 0.01 and 100 percent by weight; and
Methyl sulfonyl methane present in an amount between about 0.01 and 100 percent by weight.

47. A method for decreasing oxidative DNA damage, said method comprising the steps of:

administering a naturaceutical composition to a mammal, said naturaceutical composition comprising:
at least one processed Morinda citrifolia product present in an amount between about 0.01 and 100 percent by weight.

48. A method for decreasing the division rate of tumor cells, said method comprising the steps of:

administering a naturaceutical composition to a mammal, said naturaceutical composition comprising:
at least one processed Morinda citrifolia product present in an amount between about 0.01 and 100 percent by weight.

49. A method for inhibiting and preventing mutagenesis within a mammal, said method comprising the steps of:

introducing an internal composition into the body of said mammal, said internal composition comprising:
at least one processed Morinda citrifolia product present in an amount between about 10-80 percent by weight; and
a carrier medium present in an amount between about 20-90 percent by weight.

50. The method of claim 49, wherein said processed Morinda citrifolia product is selected from the group consisting of processed Morinda citrifolia fruit juice, processed Morinda citrifolia puree juice, processed Morinda citrifolia dietary fiber, and processed Morinda citrifolia oil and oil extract.

51. The method of claim 49, wherein said step of introducing an internal composition comprises a method selected from the group consisting of intravenously, injection, transdermally, orally, and systemically.

52. A method for inhibiting and preventing mutagenesis and repairing existing DNA damage within a mammal, said method comprising the steps of:

introducing an internal composition into the body of said mammal, said internal composition comprising:
at least one processed Morinda citrifolia product present in an amount by weight between about 5-80 percent; and
a carrier medium present in an amount by weight between about 20-95 percent.

53. The method of claim 53, wherein said processed Morinda citrifolia product is selected from the group consisting of processed Morinda citrifolia fruit juice, processed Morinda citrifolia puree juice, processed Morinda citrifolia dietary fiber, processed Morinda citrifolia oil, and processed Morinda citrifolia oil extract.

54. The method of claim 53, wherein said step of introducing an internal composition comprises a method selected from the group consisting of intravenously, injection, transdermally, orally, and systemically.

55. A method for inhibiting and preventing mutagenesis and repairing existing DNA damage within a mammal, said method comprising the steps of:

introducing an internal composition into the body of said mammal, said internal composition comprising the ingredients of:
processed Morinda citrifolia oil present in an amount by weight between about 0.1-20 percent; and
a carrier medium present in an amount by weight between about 80-99.9 percent.

56. A method for inhibiting and preventing mutagenesis and repairing existing DNA damage within a mammal, said method comprising the steps of:

introducing an internal composition into the body of said mammal, said internal composition comprising the ingredients of:
processed Morinda citrifolia product selected from one of a fruit juice product and a puree juice produce, said processed Morinda citrifolia product present in an amount by weight between about 0.1-80 percent;
processed Morinda citrifolia oil present in an amount by weight between about 0.1-20 percent; and
a carrier medium present in an amount by weight between about 20-90 percent.

57. A method for inhibiting the drug breakdown functions of cytochrome enzymes for the purpose of facilitating antimutagenesis activity within a mammal, said method comprising the steps of:

administering an antimutagenesis medication to a patient;
administering a naturaceutical composition to said patient concurrently with said antimutagenesis medication, said naturaceutical comprising a processed Morinda citrifolia product that increases the efficacy of said antimutagenesis medication by inhibiting the medication breakdown and metabolizing functions of said cytochrome enzymes, said processed Morinda citrifolia product present in an amount by weight between 0.1 and 100 percent.

58. A naturaceutical composition for inhibiting and preventing mutagenesis and repairing DNA damage in mammals, said naturaceutical composition comprising:

at least one processed Morinda citrifolia product present in an amount between about 0.01 and 100 percent by weight.

59. The composition of claim 58, wherein said processed Morinda citrifolia product comprises Morinda citrifolia fruit juice.

60. The composition of claim 58, wherein said processed Morinda citrifolia product comprises Morinda citrifolia puree juice.

61. The composition of claim 58, wherein said processed Morinda citrifolia product comprises Morinda citrifolia puree juice concentrate.

62. The composition of claim 58, wherein said processed Morinda citrifolia product comprises Morinda citrifolia fruit juice concentrate.

63. The composition of claim 58, wherein said processed Morinda citrifolia product comprises Morinda citrifolia dietary fiber.

64. The composition of claim 58, wherein said processed Morinda citrifolia product of said naturaceutical composition further comprises an active ingredient Quercetin present in an amount between about 0.1 and 10 percent by weight.

65. The composition of claim 64, wherein said processed Morinda citrifolia product further comprises Rutin as an additional active ingredient that synergistically works with said Quercetin to induce antimutagenesis activity within said mammal.

66. The composition of claim 65, wherein said Rutin is present in an amount between about 0.1 and 10 percent by weight.

67. The composition of claim 58, wherein said naturaceutical composition is administered via a method selected from the group consisting of oral administration, transdermal administration, intravenous administration, systemic administration, and administration by injection.

68. A naturaceutical formulation for effectuating antimutagenesis activity within mammals, said naturaceutical formulation comprising:

at least one processed Morinda citrifolia product present in an amount by weight between about 0.01 and 100 percent; and
Methyl Sulfonyl methane present in an amount by weight between about 0.01 and 100 percent.