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An anti-aging composition containing: (a) at least one first active ingredient chosen from phloretin and its derivatives; (b) at least one second active ingredient chosen from cinnamic acid, resveratrol, retinol, ascorbic acid, tocopherol, and their derivatives; and (c) at least one non-aqueous organic solvent, with the proviso that if the composition contains ascorbic acid, water is present as a co-solvent.

Inventors: Sheldon R. Pinnell, Jan Zielinski, Isabelle Hansenne
Original Assignee: L'OREAL
Current U.S. Classification: 514/456; 514/458; 514/474; 514/569; 514/725; 514/733

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Claims

1. An anti-aging composition comprising:

(a) at least one first active ingredient chosen from phloretin and its derivatives;

(b) at least one second active ingredient chosen from cinnamic acid, resveratrol, retinol, ascorbic acid, tocopherol, and their derivatives; and

(c) at least one non-aqueous organic solvent; with the proviso that, if the composition contains ascorbic acid, water is present as a co-solvent.

2. The composition of claim 1, wherein (a) is present in the composition in an amount of from about 0.1 to about 10% by weight, based on the total weight of the composition.

3. The composition of claim 1, wherein (a) is present in the composition in an amount of from about 1 to about 5% by weight, based on the total weight of the composition.

4. The composition of claim 1, wherein (a) is present in the composition in an amount of from about 0.5 to about 3% by weight, based on the total weight of the composition.

5. The composition of claim 1, wherein (a) is present in the composition in an amount of from about 1 to about 2% by weight, based on the total weight of the composition.

6. The composition of claim 1, wherein (a) is phloretin.

7. The composition of claim 1, wherein (b) is a cinnamic acid derivative.

8. The composition of claim 1, wherein (b) is ferulic acid.

9. The composition of claim 1, wherein (b) is a mixture of ferulic acid and ascorbic acid.

10. The composition of claim 8, wherein ferulic acid is present in an amount of from about 0.2 to about 5% by weight, and ascorbic acid is present in an amount of from about 5 to about 20% by weight, all weights based on the total weight of the composition.

11. The composition of claim 1, wherein (b) is resveratrol.

12. The composition of claim 1, wherein (b) is present in the composition in an amount of from about 0.1 to about 20% by weight, based on the total weight of the composition.

13. The composition of claim 1, wherein (b) is present in the composition in an amount of from about 0.2 to about 15% by weight, based on the total weight of the composition.

14. The composition of claim 1, wherein (b) is present in the composition in an amount of from about 0.2 to about 10% by weight, based on the total weight of the composition.

15. An anti-aging composition comprising:

(a) about 2% by weight, phloretin;

(b) about 0.5% by weight, ferulic acid;

(c) about 15% by weight, ascorbic acid;

(d) about 30% by weight of a glycol; and
(e) remainder, to 100%, water.

16. A process for treating radical-induced damage to skin comprising contacting the skin with a composition containing:

(a) at least one first active ingredient chosen from phloretin and its derivatives;

(b) at least one second active ingredient chosen from cinnamic acid, resveratrol, retinol, ascorbic acid, tocopherol, and their derivatives;

(c) at least one non-aqueous organic solvent;

with the proviso that if the composition contains ascorbic acid, water is present as a co-solvent.

17. The process of claim 16, wherein (a) is present in the composition in an amount of from about 0.1 to about 10% by weight, based on the total weight of the composition.

18. The process of claim 16, wherein (a) is present in the composition in an amount of from about 1 to about 5% by weight, based on the total weight of the composition.

19. The process of claim 16, wherein (a) is present in the composition in an amount of from about 0.5 to about 3% by weight, based on the total weight of the composition.

20. The process of claim 16, wherein (a) is present in the composition in an amount of from about 1 to about 2% by weight, based on the total weight of the composition.

21. The process of claim 16, wherein (a) is phloretin.

22. The process of claim 16, wherein (b) is a cinnamic acid derivative.

23. The process of claim 16 wherein (b) is ferulic acid.

24. The process of claim 16, wherein (b) is a mixture of ferulic acid and ascorbic acid.

25. The process of claim 24 wherein ferulic acid is present in the composition in an amount of from about 0.2 to about 5% by weight, and ascorbic acid is present in the composition in an amount of from about 5 to about 20% by weight, all weights based on the total weight of the composition.

26. The process of claim 16, wherein (b) is resveratrol.

27. The process of claim 16, wherein (b) is present in the composition in an amount of from about 0.1 to about 20% by weight, based on the total weight of the composition.

28. The process of claim 16, wherein (b) is present in the composition in an amount of from about 0.2 to about 15% by weight, based on the total weight of the composition.

29. The process of claim 16, wherein (b) is present in the composition in an amount of from about 0.2 to about 10% by weight, based on the total weight of the composition.

30. The process of claim 16 wherein the composition comprises: (a) about 2% by weight, phloretin; (b) about 0.5% by weight, ferulic acid; (c) about 15% by weight, ascorbic acid; (d) about 30% by weight of a glycol; and (e) remainder, to 100%, water.