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A combination of Eurycoma longifolia and citrus peel extract are provided in a supplement to promote weight loss and help dieters maintain high energy levels by reducing the body's normal shift to a catabolic state during weight loss. The Eurycoma longifolia root extract preferably includes eurypeptides and the citrus peel extract preferably includes tangeretin, nobiletin, and sinensetin. The supplement can be in any suitable form and is preferably administered in conjunction with a weight loss regime that includes a caloric deficiency diet and an exercise program.

Inventor: Shawn M. Talbott
Current U.S. Classification: 424/736; 424/773; 514/4.8; 514/5.5; 514/27; 514/456

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Claims

1. A dietary supplement, comprising:

from about 1 mg to about 1000 mg of a Eurycoma longifolia root extract; and

from about 100 mg to about 500 mg of a citrus peel extract.

2. The dietary supplement of claim 1, wherein the Eurycoma longifolia is obtained by a hot water extraction process yielding 18-28% eurypeptides.

3. The dietary supplement of claim 1, wherein the effective dose comprises from about 20 mg to about 200 mg of a Eurycoma longifolia root extract containing from about 18% to about 28% eurypeptides.

4. The dietary supplement of claim 1, wherein the citrus peel extract comprises at least one of tangeretin, nobiletin, and sinensetin.

5. The dietary supplement of claim 1, wherein the citrus peel extract comprises:

from about 5 mg to about 20 mg tangeretin;

from about 5 mg to about 20 mg nobiletin, and

from about 2 mg to about 10 mg sinensetin.

6. The dietary supplement of matter of claim 1, wherein the citrus peel extract comprises at least about 10 mg polymethoxylated flavones (PMFs).

7. The dietary supplement of claim 1, wherein the citrus peel extract comprises at least about 80 mg PMFs.

8. The dietary supplement of claim 1, further comprising:

a dietary acceptable carrier prepared in a dosage form selected from the group consisting of a liquid, a gel, a tablet, a capsule, a powder, a confectionary, and a supplemented food.

9. The dietary supplement of claim 8, wherein the dietary acceptable carrier comprises an exercise beverage formulated for administration during exercise.

10. The dietary supplement of claim 8, further comprising at least one of whey protein, ginseng, caffeine, guarana, green tea extract, chromium, vanadium, and CLA.

11. A method for promoting weight loss in a human subject, the method comprising:

administering to a human subject participating in a multi-day exercise routine a dietary intake consisting of a caloric intake that is insufficient to maintain the human subject's weight over the course of the multi-day exercise routine; and

administering to the human subject a dietary supplement as defined as in claim 1.

12. A topical supplement, comprising:

from about 1 mg to about 1000 mg of a Eurycoma longifolia root extract;

from about 100 mg to about 500 mg of a citrus peel extract; and

a topical cream configured for facilitating transdermal absorption of the citrus peel extract and Eurycoma longifolia.

13. The supplement of claim 12, wherein the Eurycoma longifolia is obtained by a hot water extraction process yielding 18-28% eurypeptides.

14. A method for promoting weight loss in a human subject, the method comprising:

administering to a human subject participating in a multi-day exercise routine a dietary intake consisting of a caloric intake that is insufficient to maintain the human subject's weight over the course of the multi-day exercise routine; and

administering to the human subject a topical supplement as defined as in claim 12.

15. A method for promoting weight reduction in a human subject, the method comprising administering a supplement to a human subject in need thereof during weight loss, the supplement comprising:

an effective dose of citrus peel extract for inhibiting weight gain or promoting weight loss in a human subject; and

an effective dose of Eurycoma longifolia for promoting weight loss and maintaining energy levels during weight loss in the human subject.

16. The method of claim 15, wherein:

the effective dose of Eurycoma longifolia root extract comprises from about 1 mg to about 1000 mg; and

the effective dose of citrus peel extract comprises from about 100 mg to about 500.

17. The dietary supplement of claim 15, wherein the effective doses are defined as sufficient to reduce salivary cortisol levels by at least 5% relative to cortisol levels that would result in the absence of the administration of the citrus peel extract and Eurycoma.

18. The dietary supplement of claim 15, wherein the effective doses are defined as sufficient to decrease the cortisol:testosterone ratio by at least 5% relative to the cortisol:testosterone ratio that would result in the absence of the administration of the citrus peel extract and Eurycoma.

19. The method of claim 15, further comprising administering the supplement daily in conjunction with an exercise regime and a diet comprising a caloric deficiency.

20. The method of claim 15, wherein the Eurycoma longifolia root extract comprises from about from about 18% to about 28% eurypeptides.

21. The method of claim 15, wherein the Eurycoma longifolia root extract comprises from about 20 mg to about 200 mg of a Eurycoma longifolia root extract containing from about 18% to about 28% eurypeptides.

22. The method of claim 15, wherein the supplement is in a oral form selected from the group consisting of a shake, beverage, a tablet, a capsule, a powder, a confectionary, and a supplemented food.

23. The method of claim 15, wherein the supplement is blended with a topical cream for topical administration and the act of administering the supplement comprises topically administering the supplement.

24. The method of claim 15, wherein the citrus peel extract comprises at least one of tangeretin, nobiletin, and sinensetin.

25. A method for preventing or treating conditions enhanced by the presence of excess glucocorticoids in a mammal, the method comprising:

administering to a mammal having a caloric deficiency a therapeutically effective dose of citrus peel extract and Eurycoma longifolia root extract for reducing excess glucocorticoids in the mammal.

26. The method of claim 25, wherein the therapeutically effective dose of citrus peel extract comprises from about 100 mg to about 500 mg and the therapeutically effective dose of Eurycoma longifolia root extract comprises from about 1 mg to about 1000 mg.

27. The method of claim 26, wherein the Eurycoma longifolia root extract comprises from about from about 18% to about 28% eurypeptides.

28. The method of claim 26, further comprising placing the mammal in said caloric deficiency by administering to the mammal a reduce calorie diet in conjunction with an exercise regime.

29. The method of claim 25, wherein the excess glucocorticoids are cortisol.

30. A method for promoting weight reduction in a human subject, the method comprising administering a supplement to a human subject in need thereof during weight loss, the supplement comprising:

from about 1 mg to about 300 mg eurypeptides; and

at least about 10 mg polymethoxylated flavones.