The present invention provides methods for systematically identifying genes, proteins and/or related pathways that regulate or indicative of cell phenotypes. The present invention further provides methods for manipulating the identified genes, proteins and/or pathways to engineer improved cell lines...http://www.google.com/patents/US20090186358?utm_source=gb-gplus-sharePatent US20090186358 - Pathway Analysis of Cell Culture Phenotypes and Uses Thereof