The invention provides a method of calibrating an optical analysis system that makes use of multivariate optical signal analysis allowing to realize cost-efficient and robust implementation of a spectral analysis of an optical signal. The calibration method makes use of determining a parameter of a reference...http://www.google.com/patents/US20100042348?utm_source=gb-gplus-sharePatent US20100042348 - CALIBRATION OF OPTICAL ANALYSIS MAKING USE OF MULTIVARIATE OPTICAL ELEMENTS