Expression of tetanus toxin fragment C is accomplished employing a DNA coding sequence having a (G+C)-content that has been increased in the region from nucleotide 410 to the 3' end of the coding sequence relative to the wild-type DNA sequence. This allows the production of complete mRNA transcripts....http://www.google.com/patents/US5571694?utm_source=gb-gplus-sharePatent US5571694 - Expression of tetanus toxin fragment C in yeast
