A system and method is provided for a continual updating of the optimization of multiple operational control-variables during the operation of a nuclear reactor over a plurality of fuel cycles. A networked computer system includes one or more hosts programmed to execute an optimization process to identify...http://www.google.com/patents/US7555092?utm_source=gb-gplus-sharePatent US7555092 - System and method for continuous optimization of control-variables during operation of a nuclear reactor