Apparatus and method for non-invasively measuring at least one optical parameter of a sample, particularly a sample of tissue that comprises a plurality of layers. The at least one parameter can be used to determine the presence or concentration of an analyte of interest in the sample of tissue. The...http://www.google.com/patents/US20020084417?utm_source=gb-gplus-sharePatent US20020084417 - Non-invasive sensor capable of determining optical parameters in a sample having multiple layers