Methods and compositions are provided for the diagnosis of allergen hypersensitivity in a patient. Rare, allergen-specific cells are enriched from a complex cell population, e.g. a patient blood sample. The percentage of blood cells that bind to a particular allergen is less than 0.01%. The...http://www.google.com/patents/US5786161?utm_source=gb-gplus-sharePatent US5786161 - Isolation and characterization of allergen-binding cells for diagnosis of hypersensitivity 