Novel compounds comprising chemically reactive intermediates which can react with available reactive functionalities on blood components to form covalent linkages, where the resulting covalently-bound conjugates are found to have renin inhibition activity are provided. Specifically, the renin inhibitor...http://www.google.com/patents/US6107489?utm_source=gb-gplus-sharePatent US6107489 - Extended lifetimes in vivo renin inhibitors
