A process is provided for cleaving a polypeptide into at least two polypeptide components comprising treating a reduced, free-cysteine form of the polypeptide with a cleaving agent under conditions for cleaving the polypeptide at a desired junction between the polypeptide cleavage products. More preferably,...http://www.google.com/patents/US5464756?utm_source=gb-gplus-sharePatent US5464756 - Processes and compositions for the isolation of human relaxin