Methods and compositions for the screening and isolation of ligand-binding polypeptides, such as antibodies. In some aspects, methods of the invention enable the isolation of intact soluble antibodies comprising a constant domain. Screening methods that employ genetic packages such as bacteria and bacteriophages...http://www.google.com/patents/US20090123921?utm_source=gb-gplus-sharePatent US20090123921 - IMMUNOGLOBULIN LIBRARIES