A method of enhancing the permeability of the skin or mucosa to an analyte for diagnostic purposed is described utilizing ultrasound or ultrasound plus a chemical enhancer. If desired the ultrasound may be modulated by means of frequency modulation, amplitude modulation, phase modulation and/or combinations...http://www.google.com/patents/US5458140?utm_source=gb-gplus-sharePatent US5458140 - Enhancement of transdermal monitoring applications with ultrasound and chemical enhancers
