This invention relates to neurotrophic N-glyoxylprolyl ester compounds having an affinity for FKBP-type immunophilins, their preparation and use as inhibitors of the enzyme activity associated with immunophilin proteins, and particularly inhibitors of peptidyl-prolyl isomerase or rotamase enzyme act...http://www.google.com/patents/US6140357?utm_source=gb-gplus-sharePatent US6140357 - Small molecule inhibitors of rotamase enzyme activity
