Methods and apparatus for controlled grasping and cinching or locking of a tissue anchor are provided. In one variation, a tube is provided having a lumen and a resilient member that obstructs the lumen. A grasper may be advanced coaxially through the lumen, such that it reversibly displaces the resilient...http://www.google.com/patents/US7390329?utm_source=gb-gplus-sharePatent US7390329 - Methods for grasping and cinching tissue anchors