A method for delivering an isolated polynucleotide to the interior of a cell in a vertebrate, comprising the interstitial introduction of an isolated polynucleotide into a tissue of the vertebrate where the polynucleotide is taken up by the cells of the tissue and exerts a therapeutic effect on the vertebrate....http://www.google.com/patents/US6413942?utm_source=gb-gplus-sharePatent US6413942 - Methods of delivering a physiologically active polypeptide to a mammal