A method of increasing the synthesis and/or secretion of synaptophysin comprises administering to a patient with a neurological disease or a patient at risk of developing a neurological disease an effective quantity of a purine derivative or analogue, a tetrahydroindolone derivative or analogue, or a...http://www.google.com/patents/US20020040032?utm_source=gb-gplus-sharePatent US20020040032 - Methods for stimulation of synthesis of synaptophysin in the central nervous system