The present invention is directed to a method/system of monitoring in real time changes in concentration of glucose in tissues. Laser-induced profiles of absorbed optical energy distribution in tissues are determined via measurements of spatial (in-depth) profile of optically-induced acoustic (pressure)...http://www.google.com/patents/US6405069?utm_source=gb-gplus-sharePatent US6405069 - Time-resolved optoacoustic method and system for noninvasive monitoring of glucose