A method of aiding detection of breast cancer by computer analysis of a mammogram image includes computing filtered second spatial derivative of intensity values at the pixels of the image, in the form of a Laplacian. The filtering is iterative adaptive smoothing of the first spatial derivative, which...http://www.google.com/patents/US5365429?utm_source=gb-gplus-sharePatent US5365429 - Computer detection of microcalcifications in mammograms
