The present invention relates to amphiphilic drug-oligomer conjugates capable of traversing the blood-brain barrier (“BBB”) and to methods of making and using such conjugates. An amphiphilic drug-oligomer conjugates comprise a therapeutic compound conjugated to an oligomer, wherein the oligomer comprises...http://www.google.com/patents/US6943148?utm_source=gb-gplus-sharePatent US6943148 - Methods for delivering therapeutics across blood-barrier and for altering receptor binding affinity