The present invention is a purified cartilage extract that stimulates local cartilage formation when combined with a matrix and implanted into a mammal. This extract can conveniently be produced by a method which includes the steps of: obtaining cartilage tissue; homogenizing the cartilage tissue in...http://www.google.com/patents/US7148036?utm_source=gb-gplus-sharePatent US7148036 - DNA molecules encoding cartilage-derived morphogenetic proteins