A method and apparatus for removing minute particles from a surface of a sample are provided that prevent redeposition of the particles onto the surface. By combining thermophoresis with laser assisted particle removal (LAPR), the methods and apparatus remove minute particles (for example, micrometer...http://www.google.com/patents/US6805751?utm_source=gb-gplus-sharePatent US6805751 - Method and apparatus for removal of minute particles from a surface using thermophoresis to prevent particle redeposition