The present invention provides compositions and methods for the transdermal administration of a therapeutically effective amount of a synthetic 19-nor-progesterone (ST-1435) and an estrogen, in combination, together with, optionally, a suitable permeation enhancer....http://www.google.com/patents/US5198223?utm_source=gb-gplus-sharePatent US5198223 - Transdermal formulations, methods and devices