Disclosed are systems for and methods of registering (i.e., aligning) a deformable image with a reference image subject to a spatially variant flexibility model and/or a non-Gaussian smoothing model. These systems and methods allow for the consideration of differences between the ways in which structures...http://www.google.com/patents/US20080080788?utm_source=gb-gplus-sharePatent US20080080788 - Spatially variant image deformation
