The extent of lysis or red blood cells treated with a test solution containing a known or suspected agglutinating factor, and preferably with a lipid, serves for blood typing and cross matching, and, in addition for the detection and semi-quantitation of tumor factors and of viruses including myxoviruses...http://www.google.com/patents/US4130395?utm_source=gb-gplus-sharePatent US4130395 - Process and apparatus for detection of specific biological factors by means of osmotic hemolysis