A method of modifying protein solubility employs polyionic polymers. These facilitate the solubilization, formulation, purification and refolding of proteins especially incorrectly folded proteins and aggregated proteins. Compositions are described that are suitable for formulating TFPI. The compositions...http://www.google.com/patents/US7022672?utm_source=gb-gplus-sharePatent US7022672 - Formulation, solubilization, purification, and refolding of tissue factor pathway inhibitor
