Methods for substantially improved detection and analysis in nucleic acid hybridization assays are described. The methods provide the reliable estimation of background signal which derives primarily from nonspecific hybridization. The invention is useful in chemical, biological, medical and diagnostic...http://www.google.com/patents/US7122303?utm_source=gb-gplus-sharePatent US7122303 - Arrays comprising background features that provide for a measure of a non-specific binding and methods for using the same
