Various aspects of the present invention generally relate to nanoscale wire devices and methods for use in determining analytes suspected to be present in a sample, and systems and methods of immobilizing entities such as reaction entities relative to nanoscale wires. In one aspect, a nucleic acid, such...http://www.google.com/patents/US20060269927?utm_source=gb-gplus-sharePatent US20060269927 - Nanoscale sensors