[54] PERCUTANEOUS OXYGENATOR FOR
INDUCING A RETROGRADE PERFUSION
OF OXYGENATED BLOOD
[76] Inventor: Brack G. Hattler, 5226 Westminster PL, Pittsburgh, Pa. 15232
[21] Appl. No.: 899,018
[22] Filed: Jul. 23, 1997
[51] Int. CI.6 A61M 37/00; A61M 29/00
[52] U.S. CI 604/26; 604/101
[58] Field of Search 604/23, 93, 96,
604/101, 26; 623/3
[56] References Cited
U.S. PATENT DOCUMENTS
4,686,973 8/1987 Frisch 623/23
4,883,459 11/1989 Calderon 604/28
4,911,689 3/1990 Hattler 604/26
4,986,809 1/1991 Hattler 604/26
5,122,113 6/1992 Hattler 604/26
5,186,713 2/1993 Raible 604/4
5,207,640 5/1993 Hattler et al 604/28
5,219,326 6/1993 Hattler 604/26
5,376,069 12/1994 Hattler 604/26
5,451,207 9/1995 Yock 604/53
5,458,574 10/1995 Machold et al 604/101
5,466,216 11/1995 Brown et al 604/33
5,501,663 3/1996 Hattler et al 604/26
5,558,644 9/1996 Boyd et al 604/96
5,584,803 12/1996 Stevens et al 604/4
Primary Examiner—-Wynn Wood Coggins
Assistant Examiner—Sharon Finkel
Attorney, Agent, or Firm—Dorr, Carson, Sloan & Birney,
PC.
[57] ABSTRACT
A percutaneous oxygenator is used to induce a retrograde perfusion of oxygenated blood in a vein to a compromised organ (e.g., to the brain following a stroke, or to the heart following a heart attack). The oxygenator has an occluding balloon and an oxygenation balloon located upstream from the occluding balloon. A plurality of hollow gas-permeable fibers surround the oxygenation balloon. The oxygenator is inserted into a vein downstream from the compromised organ. An external supply of air/oxygen is connected to create a flow through the fibers and thereby oxygenate blood in the surrounding vein. A retrograde flow of oxygenated blood is induced in the vein to the compromised organ by first inflating the occluding balloon to occlude the vein and then inflating the oxygenation balloon. Both balloons are then deflated to permit the normal antegrade flow of blood through the vein. This process of inflation and deflation is periodically repeated at a rate of about 30 to 60 cycles per minute. The percutaneous oxygenator may be equipped with multiple occluding balloons for blocking several branches of the venous system leading from the compromised organ.
18 Claims, 5 Drawing Sheets
