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United States Patent [19] [11] Patent Number: 5,068,103

Kawazi et al. [45] Date of Patent: Nov. 26,1991

[54] SALBUTAMOL-CONTAINING PLASTER AND METHOD OF PRODUCING SAME

[75] Inventors: Toshikuni Kawazi; Masahiro Ono;

Nobuko Inoue, all of Kagawa, Japan

[73] Assignees: Teikoku Seiyaku Kabushiki Kaisha, Kagawa, Japan; Chiesi Farmaceutici S.p.A., Parma, Italy

[21] Appl. No.: 241,458

[22] Filed: Sep. 8,1988

[30] Foreign Application Priority Data

Sep. 8, 1987 [JP] Japan 62-224487

[51] Int. CI.' A61K 31/74; A61K 31/78;

A61K 9/70; A61K 31/135

[52] U.S. CI 424/81; 424/78;

424/443; 514/653

[58] Field of Search 514/653; 424/78, 443,

424/81

[56] References Cited

U.S. PATENT DOCUMENTS

4,568,343 2/1986 Leeper et al 514/552

4,755,384 7/1988 Mallasz 424/443

4,755,525 7/1988 Markwell et al 514/394

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