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US006289235B1
(12) United States Patent ao) Patent No.: us 6,289,235 Bi
Webber et al. (45) Date of Patent: Sep. 11,2001
(54) METHOD AND SYSTEM FOR CREATING
THREE-DIMENSIONAL IMAGES USING
TOMOSYNTHETIC COMPUTED
TOMOGRAPHY
(75) Inventors: Richard L. Webber, Winson-Salem;
Roger A. Horton, Winston-Salem, both ol NC (US)
(73) Assignee: Wake Forest University,
Winston-Salem, NC (US)
( * ) Notice: Subject to any disclaimer, the term of this patent is extended or adjusted under 35 U.S.C. 154(b) by 0 days.
(21) Appl. No.: 09/034,922
(22) Filed: Mar. 5, 1998
(51) Int. CI. A61B 6/02
(52) U.S. CI 600/426; 378/23; 382/131
(58) Field of Search 600/426; 378/38,
378/166, 205-207, 23; 382/128, 131, 285, 287, 289, 295, 298; 356/393, 398, 401,
247, 248
(56) References Cited
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5,051,904 9/1991 Griffith 378/23
5,070,454 12/1991 Griffith .
5.299,254 3/1994 Dancer et al. .
5,319,550 6/1994 Griffith .
5,359,637 10/1994 Webber 378/2
5.642,293 * 6/1997 Manthey et al. .
5.668.844 9/1997 Webber 378/2
5,828,722 * 10/1998 Ploetz et al. .
5,872,828 2/1999 Niklason et al 378/23
5,878,104 * 3/1999 Ploetz .
6,081,577 * 6/2000 Webber .
6.118.845 * 6/2000 Simon et al. . 6.120,180 * 9/2000 Graumann .
FOREIGN PATENT DOCUMENTS
2016855 9/1979 (GB) . WQ9322893 11/1993 (WO) .
OTHER PUBLICATIONS
EVS-125 X-Ray Sheer Catalog, Yunihaito Co., Ltd., Shinjuku-Ku, Tokyo.
Tsuneo Saito et al., "Three-Dimensional Quantitative Coronary Angiography," IEEE Transacations on Biomedical Engineering, vol. 37, No. 8, Aug. 1990, pp. 768-777. "Proceedings of 14th Annual Meeting of the American Association of Physicists." vol. 17, No. 6, 26-29, Jun. 1972. Philadelphia, p. 878, R.Mohan et 1., "A Computer-Assisted Rapid Method for source ocalization in Interstitial Implants," abstract.
Webber et al., "Synthesis of Arbitrary X-Ray Projections From a Finite Number of Existing Projections," SPIE, vol. 535, 1985, p. 84-91.
Grant, D.G., "Tomosynthesis: AThree-Dimensional Radiographic Imaging Technique," IEEE Transactions on BioMedical Engineering, vol. BME-19, No. 1, Jan. 1972, pp. 20-28.
Ruttimann, U.E., et al., "Restoration of Digital Multiplane Tomosynthesis by a Constrained Interation Method," IEEE Transactions on Medical Imaging, vol. ME-3. No. 3, Sep. 1984, pp. 141-148.
Ruttimann, U.E., et al., "An Optimal Synthetic Aperture for Circular Tomosynthesis," Medical Physics, vol. 16, No. 3, May/Jun. 1989, pp. 398^105.
Webber et al., "Tuned-aperture computed tompgraphy (TACTTM). Theory and application for three-dimensional dento-alveolar imaging," Dentomaxillofacial Radiology (1997) 26, pp. 53-62.
* cited by examiner
Primary Examiner—Marvin M. Lateef
Assistant Examiner—Shawna J Shaw
(74) Attorney, Agent, or Firm—Dann, Dorfman, Herrell &
Skillman, PC.
(57) ABSTRACT
A system for constructing image slices through a selected object, the system comprising an identifiable fiducial reference in a fixed position relative to the selected object, wherein the fiducial reference comprises at least two identifiable reference markers. A source of radiation is provided for irradiating the selected object and the fiducial reference to form a projected image of the selected object and the fiducial reference which is recorded by a recording medium.
23 Claims, 25 Drawing Sheets
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