APPARATUS AND PROCESS FOR EQUILIBRATING GAS AND LIQUID
 Inventor: Ronald B. Smernoff, Belmont, Calif.
 Assignee: Analytical Products, Inc., Belmont, Calif.
 Appl. No.: 697,269
 Filed: Jun. 17, 1976
 Int. CI.4 G01N 33/50; G01N 1/00;
 U.S. CI 436/174; 55/68;
261/82; 422/50; 422/68; 422/81; 422/99; 422/101; 422/102; 422/104; 436/134; 436/138;
436/11; 436/68; 436/178
 Field of Search 23/259, 253 R, 232 R,
23/254 R, 230 B, 258.5; 55/68; 422/50, 68, 81, 99, 101, 44; 436/11, 68, 174, 178; 261/82
 References Cited
U.S. PATENT DOCUMENTS
3,127,254 3/1964 Astrup et al 55/68
3,973,915 8/1976 Raffaele et al 23/259
Noonan et al, Clinical Chem., vol. 20, No. 6, 1974, pp. 660-665.
Primary Examiner—Michael S. Marcus
Attorney, Agent, or Firm—Fliesler, Dubb, Meyer &
The invention is concerned with apparatus for equilibrating an aqueous solution with gas. The apparatus includes a gas vessel having therewithin a gas of a selectable composition at a pressure above ambient atmospheric pressure. Flow control means receive flow from the vessel and control a flow rate therefrom. A solution tube is provided having an aqueous solution therewithin. Conduit means lead from the flow control means to the tube below a liquid level of the aqueous solution. Means are also provided for causing the gas to be delivered within the aqueous solution below the liquid level as a plurality of bubbles. The process of the present invention is directed at simultaneously equilibrating a plurality of aqueous solutions each with one of a plurality of gas compositions. The process comprises positioning a plurality of solutions tubes, each having an open end and a closed end, in mating fit within a respective one of a plurality of cavities formed within a heat conductive block with the open ends of the tubes upwardly and a respective one of a plurality of aqueous solutions in each of the tubes. The temperature of each of the solutions is adjusted to be substantially equal by controlling the temperature of the block to a desired value. A respective one of the plurality of gas compositions is delivered below a respective liquid level of a respective aqueous solution within each respective one of the tubes in the form of bubbles.
23 Claims, 15 Drawing Figures