(i9) United States
(12) Patent Application Publication oo) Pub. No.: US 2006/0178573 Al
Kermani et al. (43) Pub. Date: Aug. 10,2006
(54) SYSTEM AND METHOD FOR PIERCING DERMAL TISSUE
(76) Inventors: Mahyar Z Kermani, Pleasanton, CA (US); Borzu Sohrab, Los Altos, CA (US)
PHILIP S. JOHNSON
JOHNSON & JOHNSON
ONE JOHNSON & JOHNSON PLAZA
NEW BRUNSWICK, NJ 08933-7003 (US)
(21) Appl. No.: 10/511,495
(22) PCT Filed: Feb. 3, 2004
(86) PCT No.: PCT/US04/03142
Related U.S. Application Data
(60) Provisional application No. 60/452,409, filed on Mar. 6, 2003.
(51) Int. CI.
A61B 5/05 (2006.01)
(52) U.S. CI 600/347
A system for piercing dermal tissue includes a skin-piercing element (e.g., an integrated micro-needle and biosensor medical device), at least one electrical contact (e.g., an electrical skin contact) and a meter configured for measuring an electrical characteristic (e.g., resistance and/or impedance) existent between the skin-piercing element and the electrical contact(s) when the system is in use. The electrical contact(s) can be integrated with a pressure/contact ring of the meter to provide a compact and inexpensive system compatible with integrated micro-needle and biosensor medical devices. Also, a method for piercing dermal tissue that includes contacting dermal tissue (e.g., skin) with at least one electrical contact and inserting a skin-piercing element into the dermal tissue while measuring an electrical characteristic existent between the skin-piercing element and the electrical contact(s).