United States Patent   Patent Number: 5,195,521
Melton, Jr, et al.  Date of Patent: Mar. 23, 1993
 TISSUE MEASUREMENTS
 Inventors: Hewlett E. Melton, Jr., Sunnyvale, Calif.; Thomas A. Sboup, Lowell, Mass.
 Assignee: Hewlett-Packard Company, Palo Alto, Calif.
 Appl. No.: 614,780
 Filed: Not. 9, 1990
 Int. C1.5 A61B 8/00
 U.S. CI 128/660.02; 128/661.10;
 Field of Search 128/660.02, 661.04,
 References Cited
U.S. PATENT DOCUMENTS
4,483,345 11/1984 Miwa 128/660.02
4,501,277 2/1985 Hongo 128/661.04
4,733,668 3/1988 Torrence 128/660
4,790,322 12/1988 Iinuma 128/661.10
4,807,636 2/1989 Skidmore et al 128/661.10
4,913,159 4/1990 Gardin et al 128/661.10
Rational Gain Compensation for Attenuation in Cardiac Ultrasonography by Hewlett E. Melton, Jr. & David J. Skorton/Pub.:Ultrasonic Imaging 5,214-228 (1983).
Automatic Real-Time Endocardial Edge Detection in Two-Dimensional Endocardiography by Hewlett E.
A system for deriving signals representing a selected cross sectional area and volume of a region of interest in tissue. In the preferred embodiment, area and volume of a fluid filled cavity contained in tissue on a real time basis are determined by launching pulses of ultrasonic pressure waves along a plurality of scan lines, detecting the locations along each line that are in fluid, deriving a signal representing the incremental area within fluid that is between adjacent scan lines, deriving a signal representing the cross sectional area of a cavity within a region of interest by summing the incremental areas and deriving a signal representing the volume of the cavity within a region of interest by revolving each incremental area about an axis of the cavity so as to form an incremental volume of revolution and summing the volume of revolution. The volume of then entire cavity is also attained by deriving the cross sectional area as just described, raising it to the 3/2 power and multiplying it by a coefficient including a function of the ratio of the long axis cross sectional area and short axis cross sectional area. Determination of the locations in fluid in the above calculations are preferably those at which a majority of an odd number of consecutive scan lines at like ranges are in fluid.
28 Claims, 10 Drawing Sheets