(12) (10) Patent No.: US 7,079,900 B2 Greenburg et al. (45) Date of Patent: Jul. 18, 2006 (54) ELECTRODE ARRAY FOR NEURAL 6,400,989 B1* 6/2002 Eckmiller .................. .. 607/54 STIMULATION 6,458,157 B1* 10/2002 Suaning ................... .. 623/6.63 (75) Inventors: Robert J. Greenburg, Los Angeles, * Cited by examiner CA (U S); Joseph H- Sehulman, Santa Primary Examiner—Carl H. Layno Clarita, CA (US) (74) Attorney, Agent, or Firm—Scott B. Dunbar; Tomas Lendavi (73) Assignee: Second Sight Medical Products, Inc., Sylmar, CA (US) (57) ABSTRACT (*) Netieei Stlbjeet te any di5e1ail1leF,thetel'l11 Ofthis The objective of the current invention is to restore color Patent i5 eXte11ded Of adjusted Under 35 vision, in whole or in part, by electrically stimulating U-S-C 154(1)) by 601 days. undamaged retinal cells, which remain in patients with, lost or degraded visual function. The invention is a retinal color (21) APP1~ Nd? 10/202-1243 prosthesis. Functionally, There are three main parts to this _ invention. One is extemal to the eye. The second part is (22) Flledi Jul‘ 24’ 2002 internal to the eye. The third part is means for communica_ _ _ tion between those two parts. The external part has sub(65) Pnor Pubhcatlon Data systems. These include an extemal imaging means, an US 2002/0193845 A1 Deg 19, 2002 eye-tracker, a head-motion tracker, a data processor, a patient’s controller, a physician’s local controller, a physiRelated U.S. Application Data cian’s remote controller, and a telemetry means. The imag(62) Division of application No. 09/515,373, filed on Feb. igihlgriagfi ?:aygéngi.u‘ti; filggyoers gédsioeifiglllifargiel; 29, 2000, now abandoned. were functional (60) Provisional application No. 60/125,873, filed on Mar. 24, 1999_ Color information is acquired by the imaging means. The color data is processed in the video data processing unit. The (51) Int. Cl. color information is encoded by time sequences of pulses A61N 1/02 (2006.01) separated by varying amounts of time, and also with the A61F 2/14 (2006.01) pulse duration being varied in time. The basis for the color A61F 9/08 (2006.01) encoding is the individual color code reference. Direct color (52) U.S. Cl. ...................................... .. 607/54; 623/6.63 stimulation is another operational hasis for providing eolor (58) Field of Classification Search ............... .. 623/4.1, PereePtien- The eleetredes stimulate the target eells se as te 623/5_11’ 611’ 653, 654; 600/553; 607/54; create a color image for the patient, corresponding to the 123/903 original image as seen by the video camera, or other imaging See application file for complete search history. mean5~ (56) References Cited The physician’s test unit can be used to set up or evaluate
and test the implant during or soon after implantation at the patient’s bedside.
17 Claims, 32 Drawing Sheets
RETINAL E RETINA