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(12) United States Patent ao) Patent No.: Us 7,819,161 B2
Neel et al. (45) Date of Patent: Oct. 26,2010
(54) SYSTEMS AND METHODS FOR BLOOD GLUCOSE SENSING
(75) Inventors: Gary T. Neel, Weston, FL (US);
Douglas E. Bell, Coral Springs, FL
(US); T. Philip Wong, Coral Springs, FL
(US); Houston F. Voss, Fort Lauderdale,
FL (US); Allan Javier Caban,
Lakeworth, FL (US); David K. Boehm,
Lauderhill, FL (US)
(73) Assignee: Nipro Diagnostics, Inc., Ft. Lauderdale, FL (US)
( * ) Notice: Subject to any disclaimer, the term of this patent is extended or adjusted under 35 U.S.C. 154(b) by 1021 days.
(21) Appl.No.: 11/590,854
(22) Filed: Nov. 1, 2006
(65) Prior Publication Data
US 2007/0089987 Al Apr. 26, 2007
Related U.S. Application Data
(60) Continuation of application No. 10/706,458, filed on Nov. 12, 2003, now abandoned, which is a division of application No. 10/286,648, filedonNov. 1,2002, now Pat. No. 6,743,635.
(60) Provisional application No. 60/375,017, filed on Apr. 25, 2002, provisional application No. 60/375,019, filed on Apr. 25, 2002, provisional application No. 60/375,020, filed on Apr. 25, 2002, provisional application No. 60/375,054, filed on Apr. 25, 2002.
(51) Int. CI.
G01N 27/327 (2006.01)
(52) U.S. CI 156/510; 204/403.01; 204/403.02
(58) Field of Classification Search 204/403 .01,
204/403.02,403.04; 205/777.5,792; 156/510 See application file for complete search history.
(56) References Cited
U.S. PATENT DOCUMENTS
4,714,874 A 12/1987 Morris etal.
FOREIGN PATENT DOCUMENTS
EP 0 170 375 5/1990
Renda et al., "A Practical Look at Self-Monitoring of Blood Glucose," Insulin, vol. 1, No. 4, pp. 141-147, 2006.
Primary Examiner—Kaj K Olsen
(74) Attorney, Agent, or Firm—Finnegan, Henderson, Farabow, Garrett & Dunner, L.L.P.
A system for measuring a glucose level in a blood sample includes a test strip and a meter. The test strip includes a sample chamber, a working electrode, a counter electrode, fill-detect electrodes, and an auto-on conductor. A reagent layer is disposed in the sample chamber. The auto-on conductor causes the meter to wake up and perform a test strip sequence when the test strip is inserted in the meter. The meter uses the working and counter electrodes to initially detect the blood sample in the sample chamber and uses the fill-detect electrodes to check that the blood sample has mixed with the reagent layer. The meter applies an assay voltage between the working and counter electrodes and measures the resulting current. The meter calculates the glucose level based on the measured current and calibration data saved in memory from a removable data storage device associated with the test strip.
35 Claims, 19 Drawing Sheets
International Search Report, PCT/US2008/081533, dated Feb. 9, 2009.
Taiwanese Office Action dated Dec. 30, 2008, for app. 092109735. Japanese Office Action in Japanese Patent Application No. 2004500056 dated Mar. 3, 2009.
Lance S. Kuhn, "Biosensors: Blockbuster or Bomb?, Electrochemical Biosensors for Diabetes Monitoring," The Electrochemical Society Interface, pp. 26-31, Winter 1998.
International Search Report in PCT/US2005/002202, Home Diagnostics, Inc. dated Jan. 25, 2005.
International Search Report in PCT/US04/10952, Home Diagnostics, Inc. dated Apr. 14, 2005.
Supplementary European Search Report issued by the European Patent Office on Jun. 12, 2006, in Application No. 03747325.3-2204 PCT/US0312899.
International Preliminary Report on Patentability (Chapter 1 of the PCT) dated Jul. 27, 2006, for International Application No. PCT/ US2005/002202.
Japanese Office Action in Japanese Patent Application No. 2004500056 dated Jun. 29, 2010.
* cited by examiner