(12) United States Patent ao) Patent No.: Us 7,598,090 B2
Takahashi et al. (45) Date of Patent: *Oct. 6,2009
(75) Inventors: Mie Takahashi, Niihama (JP);
Masataka Nadaoka, Iyo (JP); Hirotaka
Tanaka, Ehime (JP); Fumihisa
Kitawaki, Kadoma (JP)
(73) Assignee: Matsushita Electric Industrial Co.,
Ltd., Osaka (JP)
( * ) Notice: Subject to any disclaimer, the term of this patent is extended or adjusted under 35 U.S.C. 154(b) by 0 days.
This patent is subject to a terminal disclaimer.
(21) Appl.No.: 11/492,011
(22) Filed: Jul. 24, 2006
(65) Prior Publication Data
US 2006/0275921 Al Dec. 7, 2006
Related U.S. Application Data
(62) Division of application No. 10/069,845, filedon Jun. 5, 2002, now Pat. No. 7,112,451.
(56) References Cited
U.S. PATENT DOCUMENTS
4,477,575 A 10/1984 Vogeletal.
FOREIGN PATENT DOCUMENTS
EP 0 785 430 Al 7/1997
Metzner W., et al: "A Method to Biotinylate and Histochemically Visualize Ibotenic Acid for Pharmacological Inactivation Studies," Journal of Neuroscience Methods, Elsevier Science Publisher B. V, Amsterdam, NL, vol. 76, No. 2, Oct. 3, 1997, pp. 143-150.
Primary Examiner—Bao-Thuy L Nguyen
(7'4) Attorney, Agent, or Firm—Marjama Muldoon Blasiak &
A biosensor is provided with an area in which a reagent having bleaching action is carried in a state where it can be dissolved, at least in a part of a sample application area to which an inspection target solution is applied or the downstream of the sample application area in the direction of the inspection target solution permeating, in a development layer. In the so-constituted biosensor, a colored component in the inspection target solution can be faded by the bleaching reagent, so that the color in parts other than a reactive area is reduced in consequence, whereby a visual judgment is possible and a more accurate measurement result in which a reading error by a measuring device is extremely suppressed can be obtained.
15 Claims, 10 Drawing Sheets