(54) PACKAGE FOR A PHARMACEUTICAL PRODUCT AND METHOD OF MANUFACTURING AND STERILIZING THE PACKAGE
(75) Inventors: Bernard Leroy, Quintenas (FR);
Christele Gatel, Annonay (FR); Jean
Christophe Hermange, Annonay (FR)
(73) Assignee: Novartis AG, Basel (CH)
( * ) Notice: Subject to any disclaimer, the term of this patent is extended or adjusted under 35 U.S.C. 154(b) by 624 days.
(21) Appl. No.: 10/110,916
(22) PCT Filed: Oct. 16, 2000
(86) PCT No.: PCT/EP00/10159
§ 371 (c)(1),
(2), (4) Date: Nov. 20, 2002
(87) PCT Pub. No.: WO01/28885 PCT Pub. Date: Apr. 26, 2001
(30) Foreign Application Priority Data
Oct. 18, 1999 (EP) 99120609
(51) Int. CI.
B29C 43/22 (2006.01)
B65D 83/04 (2006.01)
C12M1/24 (2006.01)
(52) U.S. CI 264/503; 206/528; 435/243;
435/289.1
(58) Field of Classification Search 264/503;
206/528; 435/243,289.1 See application file for complete search history.
(56) References Cited
U.S. PATENT DOCUMENTS
The invention relates to a plastic package for a pharmaceutical product, particularly a blister package to dispense liquids or strings, and a method of manufacturing and sterilizing said package. The blister package (1) consists of a lower base portion (2) and a cover member (3). The lower portion includes a cavity indicated generally as (4) which is advantageously formed by inclined sidewalls (5) and upstanding side walls (6) and a bottom (7) which has a circular, flat and smooth surface. The cavity (4) is surrounded by outward extending flange (8). Cover member (3) is welded completely to flange (8) around the opening of cavity (4). Cavity (4) is sized to receive a pharmaceutical product, preferably an ophthalmologic product. The inclined side walls (5) preferably have a rounded geometry to avoid sharp edges for safety reasons. The upstanding side walls (6) have preferably no rounded portions in order to stabilize the cavity (4) as in the contact area of the side walls (5, 6) and the cavity (4) is quite rigid.
