Immunostimulatory oligonucleotides and uses thereof

IMT 021 (SEQ. ID N° 1); IMT023 (SEQ. ID N° 9)

Figure 1

OCT 192 TTTTGXTTTTOTCATTTTOTTTTT

XW 191 TTTTTOTiriTrrTTTl'CXTTTTOT

net ISO ...

Mr 178 ...

XMT 177 TTTTTTTTCATTTTOTTTTTTTTT

HCt 179 TTTTTTCATTTTCWFTTTTTTTTTT

zn 175 lmawnwii A A A j. A A i A A A

ZKT 174 ... A'A'A A A A1 A TT

ZKt 173 CAl'irA'AWrA'ATT ATAT A A A T 'A 'AT

XMt 0S3 ...

IMT 022 TQCTGCAAAAGAGCAAAAGAGCAA

ODN(S) Sequence

IMT022 (SEQ.ID N°8); IMT053 (SEQ ID N°19); IMT 173 (SEQ ID N°20); IMT174 (SEQ. ID N°21); IMT 175 (SEQ ID N°22); IMT 176 (SEQ ID N°23); IMT 177 (SEQ ID N°24); IMT 178 (SEQ ID N°25); IMT 179 (SEQ. ID N°26); IMT 180 (SEQ ID N°27); IMT 181 (SEQ ID N°28); IMT 182 (SEQ ID N°29)

Figure 3a

IMT 022 (SEQ.ID N°8); IMT 053 (SEQ ID N°19); IMT 173 (SEQ ID N°20); IMT174 (SEQ. ID N°21); IMT 175 (SEQ ID N°22); IMT 176 (SEQ ID N°23); IMT 177 (SEQ ID N°24); IMT 178 (SEQ ID N°25); IMT 179 (SEQ. ID N°26); IMT 180 (SEQ ID N°27); IMT 181 (SEQ ID N°28); IMT 182 (SEQ ID N°29)

Figure 3b