The present invention is directed to compositions and methods of delivery of CoQ-10 and an amino acid solubilized in monoterpenes. Use of monoterpenes as dissolving agents, greatly effects the ability to incorporate greater amounts of bioactive CoQ-10 and the amino acid, such as carnitine, i.e., carnitine tartrate, in formulations, such as soft gel capsules. |
Citations|
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Claims1. A composition, comprising: coenzyme Q-10, carnitine and a sufficient quantity of limonene to solubilize said coenzyme Q-10 and carnitine. 2. The composition of claim 1, wherein said coenzyme Q-10 is selected from the group consisting of coenzyme Q-10, reduced coenzyme Q-10 and semi-reduced coenzyme Q-10. 3. The composition of claim 1, wherein said coenzyme Q-10 is solubilized in said limonene in an amount between about 0.1% and about 45% by weight. 4. The composition of claim 1, wherein said coenzyme Q-10 is solubilized in said limonene in an amount between about 10% and about 40% by weight. 5. The composition of claim 1, wherein said composition further comprises rice bran oil. 6. The composition of claim 1, wherein said composition further comprises beeswax. 7. The composition of claim 1, wherein said composition further comprises an antioxidant. 8. A method of supplementing coenzyme Q-10 in a subject in need thereof, comprising the step of administering an effective amount of a composition comprising coenzyme Q-10, carnitine and a sufficient quantity of limonene to solubilize said coenzyme Q-10 and carnitine. 9. The method of claim 8, wherein said coenzyme Q-10 is selected from the group consisting of coenzyme Q-10, reduced coenzyme Q-10 and semi-reduced coenzyme Q-10. 10. The method of claim 8, wherein said coenzyme Q-10 is solubilized in said limonene in an amount between about 0.1% and about 45% by weight. 11. The method of claim 8, wherein said coenzyme Q-10 is solubilized in said limonene in an amount between about 10% and about 40% by weight. 12. The method of claim 8, wherein said composition further comprises rice bran oil. 13. The method of claim 8, wherein said composition further comprises beeswax. 14. The method of claim 8, wherein said composition further comprises an antioxidant. 15. A method of supplementing coenzyme Q-10 in a subject in need thereof, comprising the step of administering an effective amount of a composition of coenzyme Q-10 encapsulated in a soft gelatin capsule, comprising coenzyme Q-10, carnitine and a sufficient quantity of limonene to solubilize said coenzyme Q-10 and carnitine within said soft gelatin capsule. 16. The method of claim 15, wherein said coenzyme Q-10 is selected from the group consisting of coenzyme Q-10, reduced coenzyme Q-10 and semi-reduced coenzyme Q-10. 17. The method of claim 15, wherein said coenzyme Q-10 is solubilized in said limonene in an amount between about 0.1% and about 45% by weight. 18. The method of claim 15, wherein said coenzyme Q-10 is solubilized in said limonene in an amount between about 10% and about 40% by weight. 19. The method of claim 15, wherein said soft gelatin capsule further comprises rice bran oil. 20. The method of claim 15, wherein said soft gelatin capsule further comprises beeswax. 21. The method of claim 15, wherein said soft gelatin capsule further comprises an antioxidant. |
