3QKJ

The PWWP domain of human DNA (CYTOSINE-5-)-METHYLTRANSFERASE 3 BETA in complex with a bis-tris molecule

Summary for 3QKJ

Entry DOI	10.2210/pdb3qkj/pdb
Descriptor	DNA cytosine-5 methyltransferase 3 beta isoform 6 variant, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, SULFATE ION, ... (4 entities in total)
Functional Keywords	dnmt3b, pwwp domain, methyltransferase 3 beta, sgc, s-adenosyl-l-methionine, transferase, zinc-finger, structural genomics, structural genomics consortium
Biological source	Homo sapiens (human)
Total number of polymer chains	4
Total formula weight	68436.92
Authors	Zeng, H.,Amaya, M.F.,Mackenzie, F.,Weigelt, J.,Sundstrom, M.,Arrowsmith, C.H.,Edwards, A.M.,Botchkarev, A.,Min, J.,Wu, H.,Structural Genomics Consortium (SGC) (deposition date: 2011-02-01, release date: 2011-03-09, Last modification date: 2024-02-21)
Primary citation	Wu, H.,Zeng, H.,Lam, R.,Tempel, W.,Amaya, M.F.,Xu, C.,Dombrovski, L.,Qiu, W.,Wang, Y.,Min, J. Structural and Histone Binding Ability Characterizations of Human PWWP Domains. Plos One, 6:e18919-e18919, 2011 Cited by PubMed: 21720545 DOI: 10.1371/journal.pone.0018919 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.04 Å)

Structure validation