… We have analyzed the expression of Notch receptors, Notch ligands, and basic helix-loop-helix
(bHLH) genes during dentate gyrus development to determine whether the need to …

… Here, we will address fundamental issues of dentate gyrus development, such as where
granule cells are generated, how they migrate to reach their destination, how the formation of a …

… During dentate gyrus development, from the earliest embryonic stages to adulthood, the
final step is cell type-specific differentiation into neurons of the appropriate phenotype with the …

… The first four steps of dentate gyrus development as we have framed them all occur
predominantly in prenatal or just born rodents. The remaining stages are most prominently postnatal …

… Emx2 is required for normal dentate gyrus development In order to better understand the
role of the Emx2 gene in dentate gyrus development, we have analysed silver-stained sections …

The ERK/MAPK pathway is an important developmental signaling pathway. Mutations in
upstream elements of this pathway result in neuro-cardio-facial cutaneous (NCFC) syndromes, …

The hippocampus is a brain area central for cognition. Mutations in the human SOX2 transcription
factor cause neurodevelopmental defects, leading to intellectual disability and seizures…

Maternal alcohol ingestion during pregnancy adversely affects the developing fetus, often
leading to fetal alcohol syndrome (FAS). One of the most severe consequences of FAS is brain …

Granule neurons in the hippocampal dentate gyrus (DG) receive their primary inputs from
the cortex and are known to be continuously generated throughout adult life. Ongoing …

The dentate gyrus (DG) of the hippocampal formation plays essential roles in learning and
memory. Defective DG development is associated with neurological disorders. Here, we show …