Transcriptomic signatures associated with underlying rapid changes in the early phase brain of bi-directional sex change in Trimma okinawae

K Tamagawa, T Sunobe… - Royal Society Open …, 2023 - royalsocietypublishing.org
Teleost fish exhibit remarkable sexual plasticity and divergent developmental systems,
including sequential hermaphroditism. One of the more fascinating models of sexual plasticity is …

A targeted histone acetyltransferase can create a sizable region of hyperacetylated chromatin and counteract the propagation of transcriptionally silent chromatin

YH Chiu, Q Yu, JJ Sandmeier, X Bi - Genetics, 2003 - academic.oup.com
… This was achieved by Sas2p's positive regulation of histone H4-K16 acetylation, which
counteracted Sir2p's negative regulation of H4-K16 acetylation, although how Sas2p was …

Epigenetic insights into GABAergic development in Dravet Syndrome iPSC and therapeutic implications

J Schuster, X Lu, Y Dang, J Klar, A Wenz, N Dahl… - bioRxiv, 2023 - biorxiv.org
Dravet syndrome (DS) is a devastating early onset refractory epilepsy syndrome caused by
variants in the SCN1A gene. A disturbed GABAergic interneuron function is implicated in the …

[HTML][HTML] Changing expression profiles of long non-coding RNAs, mRNAs and circular RNAs in ethylene glycol-induced kidney calculi rats

Y Cao, X Gao, Y Yang, Z Ye, E Wang, Z Dong - BMC genomics, 2018 - Springer
… Furthermore, those up-regulated mRNAs were obviously enriched in negative regulation of
transforming growth factor-beta secretion, positive regulation of histone H4-K16 acetylation, …