… -DNA glycosylase (TDG) enzymes form a homologous family of DNA glycosylases that initiate
base-excision repair … In crystallographic studies of human UDG complexes with uracil-DNA …

… several protein–DNA complexes in the process of repair and … yeast OGG1, a DNA glycosylase
responsible for repair of 8-… In most of the cases, the complex of DNA with a glycosylase …

… vivo two to eight mitochondrial DNA (mtDNA) molecules are held together in a protein–DNA …
(A) Silver staining analysis of human AAG protein complexes purified from mock or 2 mM …

… which alkyladenine DNA glycosylase (AAG), a human DNA glycosylase responsible for the
… be difficult to detect under these conditions because the residence time of AAG on the DNA is …

… in the genome and initiating base excision DNA repair. Recent … Here, we refer to these as
the UDG, AAG and MutM/Fpg … two different MutM–DNA recognition complexes. A flexible loop …

… affinity chromatography resulted in the formation of a new 55 kDa protein–DNA complex and
… of whether the two OG glycosylase/lyases that give rise to trapped complexes 1 and 2 might …

… DNA glycosylase (AAG) initiates the base excision repair … that AAG uses facilitated diffusion
to efficiently search DNA to … searching complexes. The ability of the mutant proteins to …

… For instance, in the case of alkylpurine–DNA glycosylase (AAG), … These protein–DNA and
protein–protein interactions have … been found to form complexes with DNA glycosylases: XPG (…

… (B) View of the wtUDG/U·A DNA complex depicted similarly to the complex in (A), … DNA
glycosylase damage detection from our UDG–DNA complexes: electrostatic orientation, B-DNA …

… characterize specific protein–DNA interactions in the … spectra of the corresponding protein–DNA
“complexes”. The … coli Fpg·THF–DNA complex, we calculate that the process is driven by …